Adipose-derived stem cell exosome incubator

Abstract

The utility model relates to the technical field of cell culture, and discloses an adipose-derived stem cell exosome incubator which comprises a base, the top surface of the base is fixedly connected with an incubator body, one surface of the incubator body is provided with four culture bins, grooves of the four culture bins are internally connected with drawing boxes in a sliding mode, and the drawing boxes are connected with the culture bins in a sliding mode. Handles are fixedly connected to one faces of the four drawing boxes, a fixing plate is fixedly connected to the interior of one face of one drawing box, four T-shaped sliding grooves are formed in the top face of the fixing plate, and two T-shaped clamping plates are slidably connected to the interior of each T-shaped sliding groove. A culture dish is placed on the top face of the fixing plate and the opposite sides of the two T-shaped clamping plates, then the distance between the two T-shaped clamping plates is adjusted by twisting a twisting block, the culture dish is fixedly clamped by the two T-shaped clamping plates, the internal structures of the four drawing boxes are the same, and therefore convenience and practicability of the device are embodied.

Description

Technical Field

[0001] The utility model relates to the technical field of cell culture, and more specifically to an adipose stem cell exosome culture box. Background Art

[0002] Adipose stem cells are a type of stem cells with multidirectional differentiation potential that have been separated from adipose tissue in recent years. They mainly restore the repair function of tissue cells. In order to improve the quality of cell culture, a culture device is used to assist in the culture. In order to improve the quality of cell culture, a culture device is used to assist in the culture. In the prior art, application number CN213113363U discloses an adipose stem cell exosome culture box comprising an outer frame and three supporting plates located in the inner cavity of the outer frame, wherein the supporting plates are respectively located on the upper, middle and lower sides of the inner cavity of the outer frame, and the upper, middle and lower sides of the inner cavity of the outer frame are fixedly installed with horizontal plates respectively located under each supporting plate, and two limit blocks are fixedly installed on both sides of the three horizontal plates, and two first vertical rods are fixedly installed on both sides of the bottom surface of each supporting plate. The novel adipose stem cell exosome culture device places the culture dish between the two clamps by moving the clamps to both sides, so that the first magnet is magnetically connected to the second magnet, and then the two clamps are released. Under the action of the spring, the two clamps clamp the left and right sides of the culture dish, and the culture dish is located between the two cross bars, so that the novel adipose stem cell exosome culture device achieves the beneficial effect of effectively fixing the culture dish.

[0003] In the above technology, two clamps are moved to fix the culture device, which requires both hands to move, and the clamps are released after the culture dish is placed. It is difficult to achieve single-person operation, and the fixing method of the culture dish is inconvenient to use. Utility Model Content

[0004] In order to overcome the above-mentioned defects of the prior art, the utility model provides an adipose stem cell exosome culture box to solve the problems existing in the above-mentioned background technology.

[0005] The utility model provides the following technical solutions: an adipose stem cell exosome culture box, comprising a base, the top surface of the base is fixedly connected to the culture box, one side of the culture box is provided with four culture bins, the grooves of the four culture bins are all slidably connected with pull-out boxes, one side of the four pull-out boxes is fixedly connected with handles, one side of one pull-out box is fixedly connected with a fixed plate, the top surface of the fixed plate is provided with four T-shaped grooves, the grooves of the four T-shaped grooves are all slidably connected with two T-shaped clamping plates, the middle parts of the opposite surfaces of the eight T-shaped clamping plates are threadedly sleeved with four positive and negative threaded rods, and the top surface of the fixed plate is provided with two notches near both sides;

[0006] Preferably, both sides of the eight T-shaped clamps are fixedly connected with sliders, the sixteen sliders are slidably connected to the two sides of the four T-shaped slots, one end of the four forward and reverse threaded rods is fixedly connected with a first bevel gear, and one side of the outer wall of the four first bevel gears is meshedly connected with a second bevel gear.

[0007] Preferably, a connecting column is fixedly connected to the middle part of the top surface of the four second bevel gears, and a clamping block is movably connected to the outer walls of the four connecting columns. A plurality of clamping grooves are opened on the outer walls of the four connecting columns, and the grooves of the plurality of clamping grooves are arranged with inclined surfaces. The four connecting columns are movably connected to the inclined surfaces of the four clamping grooves through the inclined surfaces of the four clamping blocks, and a torsion block is fixedly connected to the top surfaces of the four connecting columns.

[0008] Preferably, a pushing block is fixedly connected to the middle of the top surface of the four clamping blocks, the outer walls of the four pushing blocks are slidably connected to the grooves of the four notches, and one end of the four clamping blocks is fixedly connected to a spring telescopic rod.

[0009] Preferably, outer walls of the four twisting blocks penetrate the top surface of the fixing plate, and the four twisting blocks are rotatably connected to the top surface of the fixing plate.

[0010] Preferably, a handrail is fixedly connected to one side of the incubator, sleeves are fixedly connected to the four corners of the bottom surface of the base, and the outer walls of the four sleeves are provided with two arc grooves. The inner tops of the four sleeves are fixedly connected to threaded sleeves, the four threaded sleeves are threadedly sleeved with threaded rods, the outer walls of the four threaded rods are fixedly sleeved with torsion blocks, the bottom ends of the four threaded rods are fixedly connected to anti-sliding blocks, and the four threaded rods are located inside the four sleeves.

[0011] Technical effects and advantages of the utility model:

[0012] 1. The utility model provides a pull-out box. After the staff pulls out the pull-out box, they place the culture dish on the top surface of the fixed plate and the opposite sides of the two T-shaped clamps. Then, the distance between the two T-shaped clamps is adjusted by twisting the twisting block, and the two T-shaped clamps fix the culture dish. The internal structures of the four pull-out boxes are the same, which reflects the convenience and practicality of the equipment.

[0013] 2. The utility model sets forward and reverse threaded rods, and two T-shaped clamps are threadedly sleeved on the outer walls of the forward and reverse threaded rods near both ends. The forward and reverse threaded rods are driven to rotate by rotating the twisting block, so that the two T-shaped clamps are moved in the same direction, thereby reflecting the convenience of the equipment. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 It is a schematic diagram of the overall structure of the utility model.

[0015] Figure 2 It is a schematic diagram of the fixing plate structure of the utility model.

[0016] Figure 3 This is a cross-sectional view of the T-shaped slide structure of the utility model.

[0017] Figure 4 It is a schematic diagram of the structure of the positive and negative threaded rod of the utility model.

[0018] Figure 5 It is an exploded view of the card block structure of the utility model.

[0019] Figure 6 It is an exploded view of the sleeve structure of the utility model.

[0020] The accompanying drawings are marked as follows: 1. base; 2. incubator; 3. incubator chamber; 4. pull-out box; 5. handle; 6. fixing plate; 7. T-shaped slide groove; 8. positive and negative threaded rod; 9. T-shaped clamp; 10. slider; 11. first bevel gear; 12. second bevel gear; 13. connecting column; 14. slot; 15. twist block; 16. clamp block; 17. push block; 18. spring telescopic rod; 19. notch; 20. sleeve; 21. handrail; 22. arc groove; 23. threaded sleeve; 24. threaded rod; 25. twist block; 26. anti-sliding block. DETAILED DESCRIPTION

[0021] The technical solution of the present invention will be clearly and completely described below in conjunction with the drawings in the present invention. In addition, the forms of the various structures recorded in the following embodiments are merely illustrative. The adipose stem cell exosome culture box involved in the present invention is not limited to the various structures recorded in the following embodiments. All other embodiments obtained by ordinary technicians in this field without making creative work belong to the scope of protection of the present invention.

[0022] The utility model provides an adipose stem cell exosome culture box, comprising a base 1, a culture box 2 is fixedly connected to the top surface of the base 1, four culture chambers 3 are provided on one side of the culture box 2, drawer boxes 4 are slidably connected in grooves of the four culture chambers 3, handles 5 are fixedly connected to one side of the four drawer boxes 4, a fixed plate 6 is fixedly connected to one side of a drawer box 4, four T-shaped grooves 7 are provided on the top surface of the fixed plate 6, two T-shaped clamps 9 are slidably connected in the grooves of the four T-shaped grooves 7, four positive and negative threaded rods 8 are threadedly sleeved in the middle of the opposite surfaces of the eight T-shaped clamps 9, and two notches 19 are provided on the top surface of the fixed plate 6 near both sides.

[0023] By setting up the pull-out box 4, after the staff pulls out the pull-out box 4, the culture dish is placed on the top surface of the fixed plate 6 and on the opposite sides of the two T-shaped clamps 9, and then the distance between the two T-shaped clamps 9 is adjusted by twisting the twisting block 15, and the two T-shaped clamps 9 fix the culture dish. The internal structure of the four pull-out boxes 4 is the same, which reflects the convenience and practicality of the equipment.

[0024] Furthermore, sliders 10 are fixedly connected to both sides of the eight T-shaped clamps 9, sixteen sliders 10 are slidably connected to both sides of the four T-shaped slots 7, one end of the four forward and reverse threaded rods 8 is fixedly connected to the first bevel gear 11, and one side of the outer wall of the four first bevel gears 11 is meshedly connected to the second bevel gear 12.

[0025] By setting the forward and reverse threaded rod 8, two T-shaped clamps 9 are threadedly sleeved on the outer wall of the forward and reverse threaded rod 8 near both ends. The forward and reverse threaded rod 8 is driven to rotate by rotating the twisting block 15, so that the two T-shaped clamps 9 are moved in the same direction, thereby reflecting the convenience of the equipment.

[0026] Furthermore, a connecting column 13 is fixedly connected to the middle part of the top surface of the four second bevel gears 12, and a clamping block 16 is movably connected to the outer wall of the four connecting columns 13. A plurality of clamping grooves 14 are opened on the outer wall of the four connecting columns 13, and the grooves of the plurality of clamping grooves 14 are arranged as inclined surfaces. The four connecting columns 13 are movably connected to the inclined surfaces of the four clamping grooves 14 through the inclined surfaces of the four clamping blocks 16, and the top surfaces of the four connecting columns 13 are fixedly connected to a torsion block 15.

[0027] By providing the T-shaped clamping plate 9, the T-shaped clamping plate 9 slides in the groove of the T-shaped slide groove 7 through the sliders 10 on both sides, so that the stability of the T-shaped clamping plate 9 when moving is improved, and the culture dish can be clamped more firmly.

[0028] Furthermore, a push block 17 is fixedly connected to the middle of the top surface of the four blocks 16 , the outer walls of the four push blocks 17 are slidably connected to the grooves of the four notches 19 , and one end of the four blocks 16 is fixedly connected to a spring telescopic rod 18 .

[0029] By setting the first bevel gear 11, the four first bevel gears 11 are fixedly connected to one end of the four forward and reverse threaded rods 8, and the outer walls of the four first bevel gears 11 are meshed and connected with the four second bevel gears 12 to drive, so that the staff can twist a twisting block 15 to control the two T-shaped clamps 9 to move in the same direction, thereby reflecting the convenience and practicality of the equipment.

[0030] Furthermore, the outer walls of the four twisting blocks 15 penetrate the top surface of the fixing plate 6 , and the four twisting blocks 15 are rotatably connected to the top surface of the fixing plate 6 .

[0031] By setting a twisting block 15, when one of the four twisting blocks 15 is twisted by a staff member, the bottom end of the twisting block 15 is connected to the second bevel gear 12, and the rotation of the second bevel gear 12 drives the first bevel gear 11 to rotate, thereby rotating the forward and reverse threaded rods 8. When the forward and reverse threaded rods 8 rotate, the two T-shaped clamps 9 are moved inward or outward at the same time.

[0032] Furthermore, a handrail 21 is fixedly connected to one side of the incubator 2, and sleeves 20 are fixedly connected to the four corners of the bottom surface of the base 1, and the outer walls of the four sleeves 20 are provided with two arc grooves 22. The inner tops of the four sleeves 20 are fixedly connected to threaded sleeves 23, and the four threaded sleeves 23 are threadedly sleeved with threaded rods 24, and the outer walls of the four threaded rods 24 are fixedly sleeved with torsion blocks 25, and the bottom ends of the four threaded rods 24 are fixedly connected to anti-sliding blocks 26, and the four threaded rods 24 are located inside the four sleeves 20.

[0033] By setting the clamping block 16, when the twisting block 15 is twisted clockwise, the positive and negative threaded rod 8 drives the two T-shaped clamping plates 9 connected by the outer wall thread sleeve to move toward the middle part of the positive and negative threaded rod 8. When the twisting block 15 rotates counterclockwise, it is necessary to push the pushing block 17 to make one end of the inclined surface of the clamping block 16 away from the clamping groove 14, thereby unlocking the counterclockwise rotation of the twisting block 15. At this time, twisting the twisting block 15 counterclockwise makes the two T-shaped clamping plates 9 move toward the two ends of the positive and negative threaded rod 8 at the same time, so that the two T-shaped clamping plates 9 are away from the clamped culture dish. When the pushing block 17 is released, the clamping block 16 is reset by the spring telescopic rod 18 fixedly connected at one end and clamps the clamping groove 14 again, thereby locking the twisting block 15. The staff can move the anti-sliding block 26 out of the sleeve 20 and contact the bottom surface by rotating the twisting block 25, thereby adjusting the height of the equipment, thereby reflecting the convenience and practicality of the equipment.

[0034] The working principle of the utility model is as follows: after the staff member pulls out the pull-out box 4, the culture dish is placed on the top surface of the fixed plate 6 and on the opposite side of the two T-shaped clamps 9, and then the spacing between the two T-shaped clamps 9 is adjusted by twisting the twisting block 15, so that the two T-shaped clamps 9 can fix the culture dish. The internal structure of the four pull-out boxes 4 is the same, and the two T-shaped clamps 9 are threadedly sleeved on the outer wall of the positive and negative threaded rods 8 near both ends. By rotating the twisting block 15, the positive and negative threaded rods 8 are driven to rotate, so that the two T-shaped clamps 9 are moved in the same direction, and the T-shaped The clamping plate 9 slides in the groove of the T-shaped slide groove 7 through the sliders 10 on both sides, so that the stability of the T-shaped clamping plate 9 when moving is improved. The four first bevel gears 11 are fixedly connected to one end of the four positive and negative threaded rods 8, and the outer walls of the four first bevel gears 11 are meshed and connected with the four second bevel gears 12 to drive, so that the staff twists a twisting block 15 to control the two T-shaped clamping plates 9 to move in the same direction. When the staff twists one of the four twisting blocks 15, the bottom end of the twisting block 15 is connected to the second bevel gear The second bevel gear 12 rotates to drive the first bevel gear 11 to rotate, thereby rotating the positive and negative threaded rod 8. When the positive and negative threaded rod 8 rotates, the two T-shaped clamps 9 are moved inward or outward at the same time. When the twisting block 15 is twisted clockwise, the positive and negative threaded rod 8 drives the two T-shaped clamps 9 with the outer wall thread sleeve to move toward the middle of the positive and negative threaded rod 8. When the twisting block 15 rotates counterclockwise, it is necessary to push the pushing block 17 to make one end of the inclined surface of the clamping block 16 away from the clamping slot 14, thereby unlocking the twisting block 15 from rotating counterclockwise. When the pushing block 17 is released, the clamping block 16 is reset through the spring telescopic rod 18 fixed at one end and clamps the clamping groove 14 again, thereby locking the twisting block 15. The staff can move the anti-sliding block 26 out of the sleeve 20 and contact the bottom surface by rotating the twisting block 25, thereby adjusting the height of the equipment, thereby reflecting the convenience and practicality of the equipment.

[0035] Finally, a few points should be explained: First, in the description of this application, it should be noted that, unless otherwise specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, which may refer to mechanical connection or electrical connection, or internal communication between two components, or direct connection. "upper", "lower", "left", "right", etc. are only used to indicate relative positional relationships. When the absolute position of the object being described changes, the relative positional relationship may change;

[0036] Secondly: In the drawings of the embodiments disclosed in the present utility model, only the structures related to the embodiments disclosed in the present utility model are involved, and other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of the present utility model can be combined with each other;

[0037] Finally: The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present utility model should be included in the protection scope of the present utility model.

Claims

1. An adipose stem cell exosome culture box, comprising a base (1), characterized in that: The top surface of the base (1) is fixedly connected to a culture box (2), one side of the culture box (2) is provided with four culture chambers (3), the grooves of the four culture chambers (3) are slidably connected to pull-out boxes (4), one side of the four pull-out boxes (4) is fixedly connected to a handle (5), one side of one pull-out box (4) is fixedly connected to a fixed plate (6), the top surface of the fixed plate (6) is provided with four T-shaped grooves (7), the grooves of the four T-shaped grooves (7) are slidably connected to two T-shaped clamping plates (9), the middle parts of the opposite surfaces of the eight T-shaped clamping plates (9) are threadedly sleeved with four positive and negative threaded rods (8), and the top surface of the fixed plate (6) is provided with two notches (19) near both sides.

2. The adipose stem cell exosome culture box according to claim 1, characterized in that: Both sides of the eight T-shaped clamping plates (9) are fixedly connected with sliders (10), and the sixteen sliders (10) are slidably connected to both sides of the grooves of the four T-shaped slide grooves (7). One end of the four forward and reverse threaded rods (8) is fixedly connected with a first bevel gear (11), and one side of the outer wall of the four first bevel gears (11) is meshedly connected with a second bevel gear (12).

3. The adipose stem cell exosome culture box according to claim 2, characterized in that: A connecting column (13) is fixedly connected to the middle of the top surface of the four second bevel gears (12); a clamping block (16) is movably clamped on the outer wall of the four connecting columns (13); a plurality of clamping grooves (14) are opened on the outer wall of the four connecting columns (13); the grooves of the plurality of clamping grooves (14) are arranged with inclined surfaces; the four connecting columns (13) are movably clamped to the inclined surfaces of the four clamping grooves (14) through the inclined surfaces of the four clamping blocks (16); and a torsion block (15) is fixedly connected to the top surface of the four connecting columns (13).

4. The adipose stem cell exosome culture box according to claim 3, characterized in that: A push block (17) is fixedly connected to the middle of the top surface of the four clamping blocks (16), the outer walls of the four push blocks (17) are slidably connected to the grooves of the four notches (19), and one end of the four clamping blocks (16) is fixedly connected to a spring telescopic rod (18).

5. The adipose stem cell exosome culture box according to claim 4, characterized in that: The outer walls of the four twisting blocks (15) penetrate the top surface of the fixing plate (6), and the four twisting blocks (15) are rotatably connected to the top surface of the fixing plate (6).

6. The adipose stem cell exosome culture box according to claim 2, characterized in that: A handrail (21) is fixedly connected to one side of the incubator (2); sleeves (20) are fixedly connected to the four corners of the bottom surface of the base (1); the outer walls of the four sleeves (20) are each provided with two arc-shaped grooves (22); the inner top ends of the four sleeves (20) are fixedly connected to threaded sleeves (23); the four threaded sleeves (23) are threadedly sleeved with threaded rods (24); the outer walls of the four threaded rods (24) are fixedly sleeved with torsion blocks (25); the bottom ends of the four threaded rods (24) are fixedly connected to anti-sliding blocks (26); and the four threaded rods (24) are located inside the four sleeves (20).

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