Rotary freeze drying equipment

Abstract

The utility model relates to the field of biological medicine, and discloses rotary freeze drying equipment which comprises a shell, two mounting plates are fixedly arranged on the front side and the rear side of the inner bottom end of the shell, and rotating shafts are rotationally arranged at the opposite ends of every two mounting plates. Two of the four rotating shafts penetrate through the mounting plate and are communicated to the rear end of the mounting plate to be fixedly sleeved with a second gear, the outer ends of the four rotating shafts are fixedly sleeved with slotting fixing rings, rotating rings are rotationally arranged at the ends, opposite in pairs, of the four slotting fixing rings, and fixing columns are fixedly arranged at the front ends of the rotating rings; a storage plate is rotationally arranged between every two opposite fixing columns in a sleeving mode, fixing blocks are fixedly arranged at the ends, between every two opposite rotating shafts, of the four rotating shafts, and a plurality of connecting columns are fixedly arranged at the outer ends of the four fixing blocks. According to the vacuum freeze-drying device, the problem of non-uniform local drying is avoided through vacuum freeze-drying.

Description

Technical Field

[0001] The utility model relates to the field of biomedicine, in particular to a rotary freeze-drying device. Background Art

[0002] Medicine refers to the general term for drugs and medical devices, including the production, research, development, and sales of drugs. Freeze-drying equipment is needed in the process of drug production. During the freeze-drying process, the drug is in a frozen state, which is conducive to slowing down the rate of chemical reactions, prolonging the stability of the drug, and maintaining the effectiveness of the drug in long-term storage.

[0003] Conventional freeze-drying methods include spray freeze drying and microwave freeze drying. Spray freeze drying is prone to clogging during long-term use, which affects the spray uniformity and drying effect. In addition, due to the generation of dust, there is a risk of dust explosion, which requires additional safety measures. Microwave freeze drying will cause uneven drying inside the sample due to the limited penetration depth of microwaves. In addition, microwave freeze drying equipment is relatively complex, requiring precise control of microwave power and frequency, and the operation is relatively technically complex.

[0004] Therefore, those skilled in the art provide a rotary freeze-drying device to solve the problems raised in the above background technology. Utility Model Content

[0005] The purpose of the utility model is to solve the shortcomings of the prior art and to propose a rotary freeze-drying device. Through vacuum freeze drying, the moisture will directly sublime from the solid state, making the drying process more uniform and avoiding the problems of local overheating or uneven drying. In addition, during the vacuum freeze drying process, due to the sublimation of moisture under low temperature conditions, it is helpful to maintain the activity and stability of the drug and reduce the damage of heat-sensitive substances.

[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a rotary freeze-drying device, comprising a shell, a motor is fixedly arranged on one side of the inner end of the shell, a first gear is rotatably sleeved on the output end of the motor, two mounting plates are fixedly arranged on the front and rear sides of the inner bottom end of the shell, a rotating shaft is rotatably arranged on one end of four mounting plates opposite to each other, two of the four rotating shafts penetrate the mounting plate and pass to the rear end of the mounting plate and are fixedly sleeved with a second gear, a slotted fixing ring is fixedly arranged on the outer end of the four rotating shafts, a rotating ring is rotatably arranged on one end of the four slotted fixing rings opposite to each other, and the rotating ring A fixing column is fixedly arranged at the front end, and a plurality of the fixing columns are rotatably sleeved with a storage plate between two of them, and storage grooves are provided at the upper ends of the plurality of storage plates, and a fixing block is fixedly arranged at one end between two of the four rotating shafts, and a plurality of connecting columns are fixedly arranged at the outer ends of the four fixing blocks, a partition is fixedly arranged at the upper end of the inner end of the shell, a vacuum pump is fixedly arranged at the edge of one side of the upper end of the partition, an exhaust pipe is penetrated through the inner end of the shell, a filter box is fixedly arranged at the rear end of the exhaust pipe, an activated carbon filter layer is movably arranged at the inner end of the filter box, and a heater is fixedly arranged at the middle position of the upper end of the partition;

[0007] Through the above technical solution, first open the refrigeration plate, then turn on the motor, gear No. 1 drives gear No. 2 to rotate, so that the rotating shaft will drive the fixed block to rotate. Since the fixed block and the fixed column are connected by the connecting column, and the fixed column and the rotating ring are fixedly connected, the fixed column will also rotate after the fixed block rotates. Since there is liquid medicine in the storage tank, and the fixed column and the storage plate are rotatably arranged, the liquid medicine will not invert in the opposite direction. After rotating for a period of time, turn on the vacuum pump to suck away the air inside the shell, and finally turn on the heater. The filter box will filter the air before entering the shell, so that the liquid medicine can be freeze-dried.

[0008] Furthermore, two cooling plates are fixedly arranged at the bottom end of the shell, and the two cooling plates are fixedly arranged at the lower ends of the plurality of storage plates;

[0009] Through the above technical solution, the two refrigeration plates can ensure that the temperature distribution at the bottom of the shell is more uniform, thereby accelerating the freeze-drying speed of the medicine solution.

[0010] Furthermore, the two refrigeration plates are fixedly arranged in the groove of the slotted fixing ring, and the two refrigeration plates are fixedly arranged between two of the four mounting plates;

[0011] Through the above technical solution, the refrigeration plate is fixedly arranged in the groove of the slotted fixing ring, which can provide a stable support structure, ensure that the refrigeration plate will not shake or shift during operation, and ensure the stability of the refrigeration effect. By being arranged between the mounting plates, the refrigeration plate can conduct refrigeration energy more effectively, improve refrigeration efficiency, and accelerate the freeze-drying speed of the liquid medicine.

[0012] Furthermore, a plurality of the connecting posts are fixedly arranged at the outer ends of the fixing posts, and a plurality of the connecting posts are fixedly arranged at both ends of a plurality of storage plates;

[0013] Through the above technical solution, the connecting column is fixedly arranged at the outer end of the fixing column and the two ends of the storage board to provide a stable supporting structure, ensuring that the storage board will not shake or tilt during operation, thereby ensuring the stability of the operation.

[0014] Further, the first gear is meshed with the second gear, and the first gear is rotatably arranged at the inner end of the housing;

[0015] Through the above technical solution, since the No. 1 gear is rotated at the inner end of the housing, it can be ensured that vibration and noise can be reduced after the No. 1 gear is meshed with the No. 2 gear, making the mechanical transmission more stable and reducing instability during operation.

[0016] Furthermore, the vacuum pump input end passes through the housing and leads to the outer end of the housing;

[0017] Through the above technical solution, the input end of the vacuum pump passes through the shell, which can reduce the risk of leakage at the pipe connection and ensure that the vacuum pump can stably and reliably extract the vacuum and then discharge it to the outside of the shell.

[0018] Furthermore, the filter box is fixedly connected to the heater, and the output end of the heater passes through the partition and leads to the inner side of the shell near the upper end;

[0019] Through the above technical solution, the fixed connection between the filter box and the heater can ensure that the air from the heater air inlet pipe first passes through the filter box, effectively filtering out impurities and pollutants in the air, and providing cleaner air for the inner end of the device.

[0020] The utility model has the following beneficial effects:

[0021] 1. The utility model proposes a rotary freeze-drying device. Through vacuum freeze-drying, the water will sublime directly from the solid state, avoiding the problem of local overheating or uneven drying. In addition, during the vacuum freeze-drying process, due to the sublimation of water under low temperature conditions, it helps to maintain the activity and stability of the drug and reduce the damage of heat-sensitive substances.

[0022] 2. The utility model proposes a rotary freeze-drying device. Through rotary vacuum freeze-drying, the sample can be evenly heated during the drying process, and the speed of water sublimation can be accelerated, thereby improving the drying efficiency. The rotary design helps to evenly heat and sublimate the sample, which can shorten the time of the entire drying process and improve production efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 It is an axonometric drawing of the utility model;

[0024] Figure 2 It is an axonometric drawing of the partition of the utility model;

[0025] Figure 3 It is a cross-sectional view of the utility model;

[0026] Figure 4 This is the axonometric view of the first gear of the utility model;

[0027] Figure 5 It is an axonometric drawing of the connecting column of the utility model.

[0028] Legend:

[0029] 1. Casing; 2. Motor; 3. Gear No. 1; 4. Mounting plate; 5. Rotating shaft; 6. Slotted fixing ring; 7. Rotating ring; 8. Storage plate; 9. Fixed block; 10. Connecting column; 11. Vacuum pump; 12. Heater; 13. Exhaust pipe; 14. Filter box; 15. Activated carbon filter layer; 16. Partition; 17. Refrigeration plate; 18. Storage slot; 19. Gear No. 2; 20. Fixed column. DETAILED DESCRIPTION

[0030] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0031] Reference Figure 1-5 , an embodiment provided by the utility model:

[0032] A rotary freeze-drying device comprises a shell 1, a motor 2 is fixedly arranged on one side of the inner end of the shell 1, a first gear 3 is rotatably sleeved on the output end of the motor 2, two mounting plates 4 are fixedly arranged on the front and rear sides of the inner bottom end of the shell 1, a rotating shaft 5 is rotatably arranged on one end opposite to each other of the four mounting plates 4, two of the four rotating shafts 5 penetrate the mounting plates 4 and pass to the rear end of the mounting plates 4 and are fixedly sleeved with a second gear 19, a slotted fixing ring 6 is fixedly sleeved on the outer ends of the four rotating shafts 5, a rotating ring 7 is rotatably arranged on one end opposite to each other of the four slotted fixing rings 6, a fixing column 20 is fixedly arranged on the front end of the rotating ring 7, a plurality of fixing columns 20 are rotatably sleeved with a placement plate 8 between two opposite to each other, a plurality of placement plates 8 are provided with placement grooves 18 on the upper ends, a fixing block 9 is fixedly arranged on one end opposite to each other of the four rotating shafts 5, a plurality of connecting columns 10 are fixedly arranged on the outer ends of the four fixing blocks 9, a partition 16 is fixedly arranged on the upper end of the inner end of the shell 1, and one side of the upper end of the partition 16 is close to the edge A vacuum pump 11 is fixedly arranged at the housing 1, an exhaust pipe 13 is penetrated at the upper end of the inner end of the housing 1, a filter box 14 is fixedly arranged at the rear end of the exhaust pipe 13, an activated carbon filter layer 15 is movably arranged at the inner end of the filter box 14, and a heater 12 is fixedly arranged at the middle position of the upper end of the partition 16. First, the refrigeration plate 17 is turned on, and then the motor 2 is turned on. The first gear 3 drives the second gear 19 to rotate, so that the rotating shaft 5 will drive the fixed block 9 to rotate. Since the fixed block 9 and the fixed column 20 are connected by the connecting column 10, and the fixed column 20 is fixedly connected to the rotating ring 7, the fixed column 20 will rotate after the fixed block 9 rotates. Since there is liquid medicine in the storage groove 18, and the fixed column 20 and the storage plate 8 are rotatably arranged, the liquid medicine will not be inverted in the opposite direction. After rotating for a period of time, the vacuum pump 11 is turned on to suck away the air inside the housing 1, and finally the heater 12 is turned on. The filter box 14 will filter the air before entering the interior of the housing 1, so that the liquid medicine can be freeze-dried.

[0033] The motor 2 drives the gear to rotate, and then transmits the rotation to the fixed block 9 and the fixed column 20 through the connecting column 10, ensuring that the rotation of the entire system is stable and uniform, thereby ensuring the uniformity and stability of the liquid medicine in the storage tank 18. Since the fixed column 20 and the rotating ring 7 are rotating, when the fixed block 9 rotates, the fixed column 20 will also rotate accordingly, which can ensure that the liquid medicine will not be inverted in the opposite direction, and maintain the correct position of the liquid medicine in the storage tank 18.

[0034] Two refrigeration plates 17 are fixedly arranged at the bottom end of the housing 1, and the two refrigeration plates 17 are fixedly arranged at the lower ends of the plurality of storage plates 8. The two refrigeration plates 17 can ensure that the temperature distribution at the bottom end of the housing 1 is more uniform, and the speed of freeze-drying of the liquid medicine is accelerated. The two refrigeration plates 17 are fixedly arranged in the groove of the slotted fixing ring 6, and the two refrigeration plates 17 are fixedly arranged between the four mounting plates 4, and are fixedly arranged in the groove of the slotted fixing ring 6, which can provide a stable support structure, ensure that the refrigeration plates 17 will not shake or shift during operation, and ensure the stability of the refrigeration effect. By being arranged between the mounting plates 4, the refrigeration plates 17 can conduct refrigeration energy more effectively, improve refrigeration efficiency, and accelerate the speed of freeze-drying of the liquid medicine. Multiple connecting columns 10 are fixedly arranged at the outer ends of the fixing columns 20, and multiple connecting columns 10 are fixedly arranged at both ends of the plurality of storage plates 8. The connecting columns 10 are fixedly arranged at the outer ends of the fixing columns 20 and the two ends of the storage plates 8, which can provide a stable support structure, ensure that the storage plates 8 will not shake or tilt during operation, and ensure the stability of the work. The first gear 3 is meshed with the second gear 19, and the first gear 3 is rotatably arranged at the inner end of the housing 1. Due to the rotatable arrangement of the first gear 3 at the inner end of the housing 1, it can be ensured that the first gear 3 can reduce vibration and noise after meshing with the second gear 19, making the mechanical transmission more stable and reducing the instability during operation. The input end of the vacuum pump 11 passes through the housing 1 and is connected to the outer end of the housing 1. The input end of the vacuum pump 11 passes through the housing 1, which can reduce the risk of leakage at the pipe connection and ensure that the vacuum pump 11 stably and reliably extracts vacuum and then discharges it from the outer end of the housing 1. The filter box 14 is fixedly connected to the heater 12, and the output end of the heater 12 passes through the partition 16 and is connected to the inner side of the housing 1. The filter box 14 is fixedly connected to the heater 12 to ensure that the air passes through the filter box 14 from the intake pipe of the heater 12 first, effectively filtering out impurities and pollutants in the air, and providing cleaner air for the inner end of the equipment.

[0035] The rotary freeze-drying method adopted in the present invention is similar to the rotation of a Ferris wheel. When the rotating ring 7 drives the internal fixed column 20 to rotate, the fixed column 20 will also rotate at both ends of the storage plate 8, so that the medicine in the storage groove 18 will not be poured out, which is conducive to the uniform drying of the medicine, and improves the drying effect and the quality of the medicine.

[0036] Working principle: first turn on the refrigeration plate 17, then turn on the motor 2, the No. 1 gear 3 drives the No. 2 gear 19 to rotate, so that the rotating shaft 5 will drive the fixed block 9 to rotate. Since the fixed block 9 and the fixed column 20 are connected by the connecting column 10, and the fixed column 20 and the rotating ring 7 are fixedly connected, the fixed column 20 will also rotate after the fixed block 9 rotates. Since there is liquid medicine in the storage tank, and the fixed column 20 and the storage plate 8 are rotatably arranged, the liquid medicine will not be inverted in the opposite direction. After rotating for a period of time, turn on the vacuum pump 11 to suck away the air inside the shell 1, and finally turn on the heater 12. The filter box 14 will filter the air before entering the shell 1, so that the liquid medicine can be freeze-dried.

[0037] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A rotary freeze drying device, comprising a housing (1), characterized in that: A motor (2) is fixedly arranged at one side of the inner end of the housing (1), and a first gear (3) is rotatably sleeved at the output end of the motor (2). Two mounting plates (4) are fixedly arranged at the front and rear sides of the inner bottom end of the housing (1), and rotating shafts (5) are rotatably arranged at opposite ends of the four mounting plates (4). Two of the four rotating shafts (5) penetrate the mounting plates (4) and pass to the rear end of the mounting plates (4) where a second gear (19) is fixedly sleeved. The outer ends of the four rotating shafts (5) are fixedly sleeved with slotted fixing rings (6); one end of the four slotted fixing rings (6) facing each other is rotatably provided with a rotating ring (7); a front end of the rotating ring (7) is fixedly provided with a fixing column (20); a plurality of the fixing columns (20) are rotatably sleeved with a storage plate (8) facing each other; a plurality of the storage plates (8) are provided with storage grooves (18) at their upper ends; a fixing block (9) is fixedly provided at one end of the four rotating shafts (5) facing each other; and a plurality of connecting columns (10) are fixedly provided at the outer ends of the four fixing blocks (9); A partition (16) is fixedly arranged at the upper end of the inner end of the shell (1), a vacuum pump (11) is fixedly arranged at the edge of one side of the upper end of the partition (16), an exhaust pipe (13) is arranged through the upper end of the inner end of the shell (1), a filter box (14) is fixedly arranged at the rear end of the exhaust pipe (13), an activated carbon filter layer (15) is movably arranged at the inner end of the filter box (14), and a heater (12) is fixedly arranged at the middle position of the upper end of the partition (16).

2. A rotary freeze-drying device according to claim 1, characterized in that: Two refrigeration plates (17) are fixedly arranged at the inner bottom end of the outer shell (1), and the two refrigeration plates (17) are fixedly arranged at the lower ends of the plurality of storage plates (8).

3. A rotary freeze drying device according to claim 2, characterized in that: The two refrigeration plates (17) are fixedly arranged in the groove of the slotted fixing ring (6), and the two refrigeration plates (17) are fixedly arranged between two of the four mounting plates (4).

4. A rotary freeze drying device according to claim 1, characterized in that: The plurality of connecting columns (10) are fixedly arranged at the outer ends of the fixing columns (20), and the plurality of connecting columns (10) are fixedly arranged at the two ends of the plurality of storage plates (8).

5. A rotary freeze drying device according to claim 1, characterized in that: The first gear (3) is meshed with the second gear (19), and the first gear (3) is rotatably arranged at the inner end of the housing (1).

6. A rotary freeze drying device according to claim 1, characterized in that: The input end of the vacuum pump (11) passes through the outer shell (1) and leads to the outer end of the outer shell (1).

7. A rotary freeze drying device according to claim 1, characterized in that: The filter box (14) is fixedly connected to the air heater (12), and the output end of the air heater (12) passes through the partition (16) and leads to the upper end of the inner side of the outer shell (1).

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