Automatic lifting magnetic frame device

Abstract

The utility model discloses an automatic lifting magnetic frame device which comprises a box body, a step part for placing consumables is arranged at the top of the box body, a lifting panel is arranged in the box body, a magnetic ring is arranged on the lifting panel, a lifting assembly is arranged on a bottom panel of the box body, and the lifting assembly is connected with the lifting panel. The lifting assembly is connected with the lifting panel and drives the lifting panel to move, blocking pieces are arranged on the two opposite side walls of the box body, and the blocking pieces are used for pressing consumables on the step parts. Manual operation is replaced by automatic lifting, manual operation is reduced, experiment efficiency is improved, and the problem of poor contact between consumables and magnetic rings is solved.

Description

Technical Field

[0001] The utility model relates to the technical field of biological separation, in particular to an automatic lifting magnetic frame device. Background Art

[0002] The magnetic stand is an experimental device used to separate and purify small molecules. It can separate the target object by adsorbing magnetic beads in the solution to the wall of the consumable tube through a magnet.

[0003] At present, magnetic rack-related products mainly rely on manual operation. The consumables are manually placed on the corresponding magnetic rack and removed after waiting for a certain period of time. The consumables are generally PCR plates. During this operation, since the PCR plate is an integrated structure and the upper plate is thin and has a certain degree of flexibility, it often deforms slightly, resulting in poor contact of some single-tube magnetic rings, so that the magnetic ring panel cannot contact the bottom of the single tube at all the consumable holes at the same time, and the consumables need to be pressed manually. However, this approach cannot guarantee the overall magnetic suction effect, and increases the overall operation complexity and low efficiency. Summary of the invention

[0004] The technical problem to be solved by the utility model is to provide an automatic lifting magnetic frame device, which adopts automatic lifting instead of manual lifting, reduces manual operation and improves experimental efficiency, and solves the problem of poor contact between consumables and magnetic rings.

[0005] In order to solve the above technical problems, the utility model provides an automatic lifting magnetic frame device, including a box body, a step portion for placing consumables on the top of the box body, a lifting panel is provided in the box body, a magnetic ring is provided on the lifting panel, a lifting assembly is provided on the bottom panel of the box body, the lifting assembly is connected to the lifting panel and drives the lifting panel to move, and baffles are provided on two opposite side walls of the box body, and the baffles are used to press the consumables onto the step portion.

[0006] Furthermore, a base plate is provided at the bottom of the lifting panel, an elastic guide component is provided between the base plate and the lifting panel, and the base plate is provided at the bottom of the lifting component.

[0007] Furthermore, the elastic guide assembly includes a guide column, a guide sleeve and a spring, one end of the guide column is fixedly connected to the lifting panel, the guide sleeve is arranged on the base plate, the other end of the guide column passes through the guide sleeve to the other side of the base plate and is provided with a limiting protrusion, and the spring sleeve is arranged on the surface of the guide column between the lifting panel and the base plate.

[0008] Furthermore, the lifting assembly includes a columnar guide assembly and a drive motor, the columnar guide assembly is arranged between the base plate and the bottom panel, the drive motor is fixed on the bottom panel, and a gear and a rack for matching transmission are also arranged between the drive motor and the base plate.

[0009] Furthermore, an installation avoidance opening is provided on the side wall of the box body corresponding to the baffle, a flip shaft is provided in the installation avoidance opening, a rotating hole is provided in the middle of the baffle and the baffle is sleeved on the flip shaft through the rotating hole, and the baffle is also connected to the flip power mechanism.

[0010] Furthermore, the flipping power mechanism connection includes a torsion spring and a tilted lift block, the torsion spring is arranged on the flipping axis, and a limit block is also arranged on the outside of the side wall of the box body. The torsion spring provides a flipping force for the upper part of the baffle to abut against the limit block, and the tilted lift block is arranged on the lifting assembly, and the tilted lift block is used to abut against the bottom of the baffle and drive the baffle to flip.

[0011] Furthermore, a pressing convex portion is arranged at the top of the baffle, and a transmission convex portion abutting against the inclined ejector block is arranged at the bottom of the baffle.

[0012] Furthermore, a positioning plate is provided on the step portion, and an oblique guiding surface is provided on the surface of the positioning plate located inside the box body.

[0013] Furthermore, an oil pressure buffer is arranged on the bottom panel.

[0014] Furthermore, a shielding shell is provided at the bottom of the box.

[0015] Beneficial effects of the utility model:

[0016] By adding a baffle to fix the consumables on the step portion, and then cooperating with the lifting assembly, the lifting panel with the magnetic ring can exert a certain force on the bottom of the single tube of the consumables. The consumables are fixed and will not be lifted up, ensuring effective contact between the magnetic ring and the bottom of the single tube. The lifting panel is automatically raised and lowered by the lifting assembly, reducing manual operations and saving experimental time. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0018] Figure 2 This utility model Figure 1 Schematic diagram of the explosion structure;

[0019] Figure 3 This is a schematic diagram of the bottom structure of the box body of the utility model;

[0020] Figure 4 It is a schematic diagram of the connection structure between the lifting panel and the base plate of the utility model;

[0021] Figure 5 It is a structural schematic diagram of the baffle installation part of the utility model. DETAILED DESCRIPTION

[0022] The present invention will be further described below in conjunction with the accompanying drawings and specific embodiments so that those skilled in the art can better understand the present invention and implement it, but the embodiments are not intended to limit the present invention.

[0023] Reference Figures 1 to 5 As shown, an embodiment of the automatic lifting magnetic frame device of the utility model includes a box body 1, a step portion 2 for placing consumables is arranged on the top of the box body, a lifting panel 3 is arranged in the box body, a magnetic ring 4 is arranged on the lifting panel, a lifting assembly is arranged on the bottom panel of the box body, the lifting assembly is connected to the lifting panel and drives the lifting panel to move, and baffles 6 are arranged on two opposite side walls of the box body, and the baffles are used to press the consumables onto the step portion.

[0024] When in use, the consumables (multi-well PCR plate) are directly placed on the step portion at the top of the box, and the two sides of the consumable plate are pressed against the step portion by two baffles, that is, the baffles and the step portion cooperate to clamp the consumables and fix them in the lifting direction of the lifting component. Then the lifting component is actuated to drive the lifting panel to rise and abut against the bottom of multiple single tubes on the consumables, that is, the magnetic ring abuts against the bottom of the single tube, and continues to rise a short distance after abutment. Since the consumables are fixed, the magnetic ring can be pressed against the bottom of the single tube through the control of the rising distance, so that the consumables are in a taut state to offset their own deformation, so that each magnetic ring can effectively contact the bottom of the corresponding single tube, so that there is a better fitting effect when contacting the consumables. After the magnetic ring abuts against the bottom of the single tube, the magnetic beads in the internal solution can be adsorbed to the tube wall, thereby realizing the separation of the target object. After the separation is completed, the lifting component drives the lifting panel to move downward, and the magnetic beads gather to the bottom along the tube wall.

[0025] When the lifting panel is driven up by the lifting assembly and contacts the consumables, its force will continue to increase. The continuous increase in force will cause the consumables to be pushed off, so its rising distance is difficult to control. In order to solve this problem, a substrate 7 is provided at the bottom of the lifting panel, and an elastic guide assembly is provided between the substrate and the lifting panel. The substrate is provided at the bottom of the lifting assembly, and there is a lifting and moving space between the lifting panel and the substrate. After the lifting panel contacts the consumables, the lifting assembly continues to move upward, and its force will not act directly on the consumables through the lifting panel, but will compress the elastic guide assembly. The force released by the deformation of the elastic guide assembly will contact the lifting panel against the consumables. The elastic guide assembly can adopt a constant force structure to ensure that the applied pressure will not push the consumables off and can meet a good fitting effect.

[0026] Specifically, refer to Figure 4 As shown, the elastic guide assembly includes a guide column 8, a guide sleeve 9 and a spring 10. One end of the guide column is fixedly connected to the lifting panel, the guide sleeve is arranged on the base plate, the other end of the guide column passes through the guide sleeve to the other side of the base plate and is provided with a limiting protrusion 11. The limiting protrusion can be a screw. By locking it at the end of the guide column, the guide column cannot fall out of the guide sleeve, thereby achieving an overall non-separation effect. The spring sleeve is arranged on the surface of the guide column between the lifting panel and the base plate. The spring can adopt a constant force spring structure to ensure that the abutting force is constant.

[0027] Reference Figure 3 As shown, the above-mentioned lifting assembly includes a columnar guide assembly 12 and a driving motor 13. The columnar guide assembly is arranged between the base plate and the bottom panel. The driving motor is fixed on the bottom panel. A gear 14 and a rack 15 for matching transmission are also arranged between the driving motor and the base plate. The gear is driven to rotate by the motor, and the gear can drive the rack to move up and down, thereby driving the lifting panel to move up and down. The structure is simple and easy to repair and maintain.

[0028] Reference Figure 1 , Figure 2 and Figure 5 As shown, since the baffle needs to press the consumables onto the step portion, and in order to improve the automation effect, an installation avoidance opening 16 is provided on the side wall of the box corresponding to the baffle, and a flip shaft 17 is provided in the installation avoidance opening. A rotating hole is provided in the middle of the baffle and the baffle is sleeved on the flip shaft through the rotating hole. The baffle is also connected to a flip power mechanism, which can provide the baffle with rotational power along the flip shaft, so that the baffle can be pressed onto the side surface of the consumables. When the separation is completed, the flip power mechanism releases the force on the baffle, that is, the pressing force applied by the baffle to the consumables is also released, and the consumables can be easily taken away.

[0029] Specifically, the flipping power mechanism connection includes a torsion spring 18 and a tilted lift block 19. The torsion spring is arranged on the flipping axis. A limit block 20 is also arranged on the outside of the side wall of the box. The torsion spring provides a flipping force for the upper part of the baffle to abut against the limit block. The tilted lift block is arranged on the lifting assembly.

[0030] When the lifting assembly rises, the lift block can abut against the bottom of the baffle. The upper end of the lift block is the small end, and the lower end is the large end. The small end first contacts the baffle, and then gradually moves along the inclined surface to abut and apply pressure. The torsion spring is compressed and accumulates reaction force, forcing the baffle to rotate along the flip axis. The lift block is located on the inner side of the baffle, that is, the top of the baffle can rotate into the box until it is pressed against the consumable. When the lifting assembly descends, the lift block gradually releases the pressure on the baffle. At this time, the torsion spring resets and releases the action, resetting the baffle, that is, driving the baffle to rotate along the flip axis, and the upper part of the baffle rotates outside the box. Thereby, the automatic fixing effect of the baffle clamping and resetting the consumable is achieved during the movement of the lifting assembly. Specifically, the lift block can be fixed on the side of the substrate without affecting the movement of the lifting panel, and the fixing effect of the baffle is guaranteed.

[0031] In order to cooperate with the above-mentioned automated action, an extrusion protrusion 21 is provided on the top of the baffle so that the baffle can better press the consumables, and a transmission protrusion 22 abutting against the inclined top block is provided at the bottom of the baffle so that the baffle can better contact and transmit force with the inclined top block. The transmission protrusion can adopt a roller to change the friction force into rolling force, thereby reducing movement wear.

[0032] When placing consumables, they need to have an accurate placement position so that the magnetic ring can be aligned with the bottom of each single tube. Therefore, a positioning plate 23 is provided on the step portion. Multiple positioning plates cooperate to determine the placement position of the consumables. The positioning plate is located on the surface inside the box and is provided with an oblique guide surface to facilitate manual placement and placement with a robot. An oil pressure buffer 24 is provided on the bottom panel to reduce the vibration generated when the lifting assembly descends to the lowest position. A shielding shell 25 is provided at the bottom of the box. The motor can be set at the bottom of the bottom panel to facilitate heat dissipation. The shielding shell improves the aesthetics of the overall equipment.

[0033] The above embodiments are only preferred embodiments for fully illustrating the present invention, and the protection scope of the present invention is not limited thereto. Any equivalent substitution or modification made by a person skilled in the art based on the present invention is within the protection scope of the present invention.

Claims

1. An automatic lifting magnetic frame device, characterized in that: It includes a box body, a step portion for placing consumables on the top of the box body, a lifting panel is arranged in the box body, a magnetic ring is arranged on the lifting panel, a lifting component is arranged on the bottom panel of the box body, the lifting component is connected to the lifting panel and drives the lifting panel to move, and baffles are arranged on two opposite side walls of the box body, and the baffles are used to press the consumables onto the step portion.

2. The automatic lifting magnetic frame device according to claim 1, characterized in that: A base plate is arranged at the bottom of the lifting panel, an elastic guide component is arranged between the base plate and the lifting panel, and the base plate is arranged at the bottom of the lifting component.

3. The automatic lifting magnetic frame device according to claim 2, characterized in that: The elastic guide assembly includes a guide column, a guide sleeve and a spring. One end of the guide column is fixedly connected to the lifting panel. The guide sleeve is arranged on the base plate. The other end of the guide column passes through the guide sleeve to the other side of the base plate and is provided with a limited position protrusion. The spring sleeve is arranged on the surface of the guide column between the lifting panel and the base plate.

4. The automatic lifting magnetic frame device according to claim 2, characterized in that: The lifting assembly includes a columnar guide assembly and a driving motor. The columnar guide assembly is arranged between the base plate and the bottom panel. The driving motor is fixed on the bottom panel. A gear and a rack for matching transmission are also arranged between the driving motor and the base plate.

5. The automatic lifting magnetic frame device according to claim 1, characterized in that: The side wall of the box body corresponding to the baffle is provided with an installation avoidance opening, a flip shaft is provided in the installation avoidance opening, a rotating hole is provided in the middle of the baffle and the baffle is sleeved on the flip shaft through the rotating hole, and the baffle is also connected to the flip power mechanism.

6. The automatic lifting magnetic frame device according to claim 5, characterized in that: The flipping power mechanism connection includes a torsion spring and a tilted lift block, the torsion spring is arranged on the flipping shaft, and a limit block is also arranged on the outside of the side wall of the box body. The torsion spring provides a flipping force for the upper part of the baffle to abut against the limit block, and the tilted lift block is arranged on the lifting assembly. The tilted lift block is used to abut against the bottom of the baffle and drive the baffle to flip.

7. The automatic lifting magnetic frame device according to claim 6, characterized in that: The top of the baffle is provided with an extrusion convex portion, and the bottom of the baffle is provided with a transmission convex portion abutting against the inclined ejection block.

8. The automatic lifting magnetic frame device according to claim 1, characterized in that: A positioning plate is arranged on the step portion, and an oblique guiding surface is arranged on the surface of the positioning plate located inside the box body.

9. The automatic lifting magnetic frame device according to claim 1, characterized in that: An oil pressure buffer is arranged on the bottom panel.

10. The automatic lifting magnetic frame device according to claim 1, characterized in that: A shielding shell is arranged at the bottom of the box body.

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