Bidirectional dialysis device and bidirectional dialysis system

Abstract

The utility model discloses a bidirectional dialysis device and a bidirectional dialysis system, comprising: a dialyzer comprising a blood inlet, a blood outlet, a first dialysate inlet, a first dialysate outlet, a second dialysate inlet and a second dialysate outlet; the second dialysate inlet is used for being connected with a first dialysate pipeline of a dialysis machine, and the first dialysate outlet is used for being connected with a second dialysate pipeline of the dialysis machine; the third dialysate pipeline is connected with the first dialysate inlet; the fourth dialysate pipeline is connected with the second dialysate outlet; the first pump is connected with the third dialyzate pipeline and the fourth dialyzate pipeline and used for conveying dialyzate at a constant speed without being influenced by pressure, so that the flow speed of the dialyzate at two ports of the first pump is the same as that of the first dialyzate pipeline; the second pump is a reciprocating pump, is connected with the first pump in parallel and is used for periodically sucking or discharging the dialysate, and the dialysate at two ports of the second pump has the same flow speed. The pipeline is simple, high transmembrane pressure of the dialyzer caused by protein adsorption is reduced, and the cleaning effect of the dialyzer is high.

Description

Technical Field

[0001] The utility model relates to the technical field of medical devices, and more specifically, to a two-way dialysis device. In addition, the utility model also relates to a two-way dialysis system comprising the two-way dialysis device. Background Art

[0002] In clinical medicine, hemodialysis is often used as an effective maintenance treatment for patients with renal failure. Hemodialysis is a process in which blood is drawn out of the patient's body through a dialysis machine, purified by the dialyzer, and then returned to the patient's body.

[0003] The hemodialysis system includes blood lines, dialyzers and dialysis machines. The blood lines are pipes through which blood flows outside the body, and their function is similar to that of blood vessels. The dialyzer is used to exchange fluids between blood and dialysate inside the dialyzer to remove waste from the blood. The dialysis machine is used to produce dialysate, control the blood pump to provide power for the blood to flow outside the body, and monitor various parameters during the dialysis process.

[0004] At present, there are several treatment modes of hemodialysis in the prior art. The first is conventional hemodialysis. The specific pipeline connection is as follows: Figure 1 For ease of understanding, the letters Q in the figure represent flow rate; B: blood, represents blood; D: dialysis, represents dialysate; I: in, represents the inflow side; O: out, represents the outflow side. The meanings of these letters in other figures in this article are the same and will not be repeated in the following text. Figure 1 As shown, blood flows into the dialyzer 10 from top to bottom through a blood pump, and after liquid exchange with the dialysate flowing from bottom to top in the dialyzer 10, wastes in the body are discharged and finally returned to the patient's body. The dialysis machine 20 is controlled by a pump so that QDI=QDO. The pipeline connection of this hemodialysis treatment is simple, but the removal efficiency is low.

[0005] The second is pre-replacement therapy or post-replacement therapy, the principle of which is: on the basis of conventional hemodialysis, by adding replacement fluid before or after the dialyzer 10, and removing liquid equivalent to the amount of replacement fluid in the dialyzer 10, the removal effect is increased. Figure 2 The figure shows the specific pipeline connection for pre-exchange treatment. Figure 3 For the specific tubing connection of post-replacement therapy, Figure 2 and Figure 3 The dotted frame in the figure is the internal pipeline of the dialysis machine 20, which will not be described in detail here, and those skilled in the art may refer to the relevant technology; Figure 2 and Figure 3The two S points are connected by pipelines inside the dialyzer 20, and the replacement fluid is powered by the replacement fluid pump to input the blood circuit tube. In the pre-replacement mode and post-replacement mode, QDI1=QDI2+QS. For the portion flowing through the dialyzer 10, the flow rate of QDI2 flowing through the dialyzer 10 becomes QDO, so the liquid on the blood side 50 needs to be removed to the liquid with a flow rate of QS on the dialysate side 60, and the liquid with the corresponding QS flow rate is replenished into the blood circuit through the replacement fluid pump. It can be seen that for pre-replacement treatment, the replacement fluid is first added to the blood circuit before the dialyzer 10, and then removed from the dialyzer 10; for post-replacement treatment, the replacement fluid is first removed from the dialyzer 10, and then the replacement fluid is replenished after the dialyzer 10.

[0006] Another treatment method is to replace the front and back at the same time. The specific pipe connection is as follows Figure 4 As shown, the principle is the same as the above-mentioned anterior and posterior replacement treatments, except that the anterior and posterior replacements can be performed simultaneously to achieve better toxin removal effects.

[0007] Compared with the first type of hemodialysis, pre-exchange therapy, post-exchange therapy and pre- and post-exchange therapy can increase the toxin removal effect, but it also increases the complexity of the equipment and the complexity of connecting the pipelines for medical staff. The complex system increases the possibility of errors, thereby increasing the monitoring costs of medical staff. For hemodialysis, once an error occurs, the pump will stop, and stopping the pump will stop the blood from flowing outside the body, thereby increasing the risk of extracorporeal coagulation.

[0008] Furthermore, regardless of the above treatment method, as hemodialysis proceeds, the macromolecular protein 70 will be adsorbed on the inner side of the membrane filaments of the dialyzer 10 due to the effect of pressure, resulting in an increase in the transmembrane resistance of the liquid. The blockage of the membrane pores will also reduce the toxin removal effect in the blood.

[0009] The principle of the pressure inside the dialyzer 10 membrane is: when there is no dehydration, due to the effect of the semipermeable membrane, the pressure inside and outside the membrane is balanced, the pressure on the blood side 50 decreases from top to bottom, and the pressure on the dialysate side 60 increases from top to bottom. The pressure inside and outside the dialyzer 10 membrane is as follows Figure 5 As shown. At this time, the value of the pressure on the blood side 50 minus the pressure on the dialysate side 60 is 0. The amount of liquid flowing in opposite directions is equal. For ease of understanding, the center point of the pressure on the blood side 50 is marked with a small circle. Figure 6 As shown, the pressure on the blood side 50 is higher than the pressure on the dialysate side 60, and the liquid enters the dialysate side 60 from the blood side 50; Figure 7 As shown, the pressure on the blood side 50 is lower than the pressure on the dialysate side 60 , and liquid enters the blood side 50 from the dialysate side 60 .

[0010] When there is dehydration, the pressure on the dialysate side 60 will be slightly lower than that on the blood side 50, resulting in a transmembrane pressure difference, that is, the pressure on the blood side 50 minus the pressure on the dialysate side 60>0, resulting in dehydration. The magnitude of the dehydration is proportional to the transmembrane pressure difference divided by the transmembrane resistance. At this time, the pressure change on the blood side 50 remains basically unchanged, because the dialysis machine 20 adjusts the dehydration by adjusting the pressure on the dialysate side 60, such as Figure 8 As shown in FIG. 1 , the pressure change when the dialyzer 10 has dehydration. When the macromolecular protein 70 is adsorbed on the inner surface of the membrane filament, the transmembrane resistance increases. For transmembrane transport, the transport speed is proportional to the transmembrane pressure divided by the transmembrane resistance. Therefore, in order to ensure that the transport speed remains unchanged, the transmembrane pressure will inevitably increase. Fig. 9 , which is a diagram showing pressure changes when the transmembrane resistance in the dialyzer 10 increases.

[0011] For the dialyzer 10 membrane filaments, the protein 70 (e.g. Fig.10 As shown in the figure, the phenomenon of increased transmembrane pressure due to protein 70 adsorption is very common. The gradually accumulated increase in transmembrane pressure will cause the transmembrane pressure alarm of the dialysis machine 20 to be too high. Excessive transmembrane pressure can easily damage the membrane fibers of the dialyzer 10.

[0012] In summary, how to improve the blood toxin removal effect without increasing the complexity of the connecting pipelines, reduce the increase in transmembrane pressure of the dialyzer 10 caused by protein 70 adsorption, and improve the removal effect of protein 70 in the dialyzer 10 is an urgent problem to be solved by technical personnel in this field. Utility Model Content

[0013] In view of this, the purpose of the utility model is to provide a bidirectional dialysis device, which can improve the blood toxin removal effect without increasing the complexity of the connecting pipelines, reduce the increase in the dialyzer transmembrane pressure caused by protein adsorption, and improve the protein removal effect in the dialyzer.

[0014] The purpose of the utility model is to provide a bidirectional dialysis system including the above-mentioned bidirectional dialysis device, which can improve the blood toxin removal effect without increasing the complexity of the connecting pipelines, reduce the increase in the dialyzer transmembrane pressure caused by protein adsorption, and improve the protein removal effect in the dialyzer.

[0015] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0016] A two-way dialysis device, comprising:

[0017] A dialyzer, comprising a blood inlet, a blood outlet, a first dialysate inlet, a first dialysate outlet, a second dialysate inlet and a second dialysate outlet, wherein the blood inlet is arranged at the top of the dialyzer, the blood outlet is arranged at the bottom of the dialyzer, the blood inlet and the blood outlet are connected, and both are used to connect a blood pipeline, and along the direction from the top to the bottom of the dialyzer, the first dialysate outlet, the first dialysate inlet, the second dialysate outlet and the second dialysate inlet are arranged in sequence, and the first dialysate inlet is connected to the first dialysate outlet, and the second dialysate inlet is connected to the second dialysate outlet;

[0018] The second dialysate inlet is used to connect to a first dialysate pipeline of a dialyzer, and the first dialysate outlet is used to connect to a second dialysate pipeline of the dialyzer, and the dialyzer is used to control the flow rate of the dialysate transported by the first dialysate pipeline and the second dialysate pipeline to be the same through a pump;

[0019] a third dialysate pipeline connected to the first dialysate inlet;

[0020] a fourth dialysate pipeline connected to the second dialysate outlet;

[0021] a first pump, connected to the third dialysate pipeline and the fourth dialysate pipeline, respectively, for conveying the dialysate at a uniform speed without being affected by pressure, and making the dialysate flow rate at the two ports of the first pump the same as the flow rate of the dialysate conveyed by the first dialysate pipeline and the second dialysate pipeline;

[0022] The second pump is a reciprocating pump connected in parallel with the first pump and respectively connected to the third dialysate pipeline and the fourth dialysate pipeline for periodically inhaling or discharging dialysate, and the dialysate flow rates at the two ports of the second pump are the same.

[0023] Optionally, the dialyzer comprises a first dialyzer and a second dialyzer connected in series, wherein the first dialyzer comprises the blood inlet, the first dialysate inlet and the first dialysate outlet;

[0024] The second dialyzer includes the blood outlet, the second dialysate inlet, and the second dialysate outlet.

[0025] Optionally, a blood outflow through hole is provided at the bottom of the first dialyzer, a blood inflow through hole is provided at the top of the second dialyzer, and the bottom end of the first dialyzer is fixedly connected to the top end of the second dialyzer so that the blood outflow through hole is connected to the blood inflow through hole.

[0026] Optionally, the first dialyzer includes a blood connection outlet, and the second dialyzer includes a blood connection inlet, and the blood connection outlet is connected to the blood connection inlet via a connecting pipe.

[0027] A two-way dialysis system, comprising:

[0028] Any of the above two-way dialysis devices;

[0029] The dialysis machine comprises a first dialysate pipeline and a second dialysate pipeline, which are used to control, through a pump, the flow rates of the dialysate transported by the first dialysate pipeline and the second dialysate pipeline to be the same, wherein the first dialysate pipeline is connected to the second dialysate inlet of the bidirectional dialysis device, and the second dialysate pipeline is connected to the first dialysate outlet of the bidirectional dialysis device.

[0030] Optionally, a portion of the third dialysate line, a portion of the fourth dialysate line, the first pump and the second pump are integrated inside the dialysis machine.

[0031] Optionally, the first dialysate pipeline, the second dialysate pipeline, the third dialysate pipeline and the fourth dialysate pipeline are hard silicone pipelines respectively.

[0032] Optionally, the two ports of the first pump are respectively provided with a first flow rate detection device for detecting the flow rate of the two ports of the first pump to perform feedback control on the flow rate of the first pump.

[0033] Optionally, the two ports of the second pump are respectively provided with second flow rate detection devices for detecting the flow rates of the two ports of the second pump so as to perform feedback control on the flow rate of the second pump.

[0034] Optionally, the first dialysate pipeline is provided with a third flow velocity detection device for detecting the flow velocity of the first dialysate pipeline so that the dialysis machine can perform feedback control on the flow velocity of the first dialysate pipeline; the second dialysate pipeline is provided with a fourth flow velocity detection device for detecting the flow velocity of the second dialysate pipeline so that the dialysis machine can perform feedback control on the flow velocity of the second dialysate pipeline.

[0035] The bidirectional dialysis device provided by the utility model can make the flow rate of the dialysate entering the first dialysate inlet periodically greater than or less than the flow rate of the dialysate flowing out of the first dialysate outlet under the joint action of the first pump and the second pump, and make the flow rate of the dialysate entering the second dialysate inlet periodically less than or greater than the flow rate of the dialysate flowing out of the second dialysate outlet. In this way, during the dialysis process, the bidirectional dialysis device includes two processes, the first process is: the flow rate of the dialysate flowing through the second pump is positive, the dialysate pressure in the lower half of the dialyzer is reduced, and the liquid enters the dialysate side from the blood side at a speed of the dialysate flowing out of the second dialysate outlet minus the flow rate of the dialysate entering the second dialysate inlet; the dialysate pressure in the upper half of the dialyzer rises, and the liquid enters the blood side from the dialysate side at a speed of the dialysate entering the first dialysate inlet minus the flow rate of the dialysate flowing out of the first dialysate outlet. In the second process, the flow rate of the dialysate flowing through the second pump is negative, the dialysate pressure in the lower half of the dialyzer rises, and the liquid enters the blood side from the dialysate side at a speed of the flow rate of the dialysate flowing out of the second dialysate outlet minus the flow rate of the dialysate entering the second dialysate inlet; the dialysate pressure in the upper half of the dialyzer decreases, and the liquid enters the dialysate side from the blood side at a speed of the flow rate of the dialysate entering the first dialysate inlet minus the flow rate of the dialysate flowing out of the first dialysate outlet. As the second pump periodically switches, the pressure in the dialyzer changes periodically, and the above two processes are continuously cycled, that is, the first process and the second process are periodically switched, so that the dialysate alternately enters and exits the dialyzer, so that the protein adsorbed on the inner surface of the dialyzer membrane filaments can be washed away, thereby ensuring the stable performance of the dialyzer during the entire dialysis process and avoiding the performance of the dialyzer being reduced due to protein adsorption.

[0036] That is, the bidirectional dialysis device, by periodically changing the pressure on the dialysate side, enhances the flushing effect of the dialysate side liquid on the inner surface of the dialyzer membrane filaments when entering the blood side, reduces protein adsorption on the inner surface of the membrane filaments, improves the removal effect of the dialyzer membrane filaments, and increases the service life of the dialyzer, thereby avoiding a continuous increase in transmembrane pressure during dialysis.

[0037] In addition, for the first process mentioned above, the blood in the dialyzer is first diluted and then concentrated, and the effect is equivalent to the pre-exchange therapy. For the second process mentioned above, the blood in the dialyzer is first concentrated and then diluted, and the effect is equivalent to the post-exchange therapy. The first process and the second process are switched periodically, so that the dialysate alternately enters the dialyzer, which is equivalent to the dialyzer periodically performing pre-exchange therapy and post-exchange therapy, which has an effect similar to the front and back simultaneous exchange therapy, and improves the toxin removal effect of the patient. For medical staff, the pipeline connection is similar to the pipeline connection of the hemodialysis treatment mode. It is only necessary to connect two dialysate connectors on the basis of the hemodialysis pipeline connection. The pipeline connection method is simple and convenient, avoiding the complex pipeline connection of pre-exchange therapy, post-exchange therapy, and front and back simultaneous exchange therapy, reducing the processing time of medical staff and reducing treatment accidents caused by connection errors.

[0038] Further, for equipment, it is only necessary to add the third dialysate pipeline, the fourth dialysate pipeline, the first pump and the second pump, thereby avoiding complicated equipment design for the dialyzer and reducing manufacturing costs. On the basis of improving the removal effect of the dialyzer membrane filaments and avoiding the continuous increase in transmembrane pressure during the dialysis process, the effect of simultaneous replacement of the front and back can also be achieved. In addition, if traditional hemodialysis treatment is desired, only a traditional dialyzer is needed, and the dialyzer is only connected to two dialysate connectors of the first dialysate pipeline and the second dialysate pipeline, so as to achieve the effect of traditional hemodialysis treatment.

[0039] The bidirectional dialysis system provided by the utility model comprises the above-mentioned bidirectional dialysis device and has the above-mentioned beneficial effects. BRIEF DESCRIPTION OF THE DRAWINGS

[0040] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on the provided drawings without paying creative work.

[0041] Figure 1 This is a schematic diagram of the pipe connection of conventional hemodialysis in the prior art;

[0042] Figure 2 It is a schematic diagram of the pipeline connection of anterior replacement therapy in the prior art;

[0043] Figure 3 It is a schematic diagram of pipeline connection for post-replacement treatment in the prior art;

[0044] Figure 4 This is a schematic diagram of the pipeline connection for simultaneous front and back replacement therapy in the prior art;

[0045] Figure 5 It is a schematic diagram of the pressure change inside and outside the dialyzer membrane when there is no dehydration in the prior art;

[0046] Figure 6 It is a schematic diagram of liquid entering the dialysate side from the blood side in the prior art;

[0047] Figure 7 It is a schematic diagram of liquid entering the blood side from the dialysate side in the prior art;

[0048] Figure 8 It is a schematic diagram of the pressure change inside and outside the dialyzer membrane when there is dehydration in the prior art;

[0049] Fig. 9 It is a pressure change diagram when the transmembrane resistance in the dialyzer increases in the prior art;

[0050] Fig.10 It is a schematic diagram of the inner side of the dialyzer membrane fiber adsorbing protein in the prior art;

[0051] Fig.11 A schematic diagram of a bidirectional dialysis device provided in a specific embodiment of the utility model;

[0052] Fig.12 is a schematic diagram of a bidirectional dialysis device during dialysis when the flow direction of the dialysate flowing through the second pump is the same as the flow direction of the dialysate flowing through the first pump;

[0053] Fig.13 is a schematic diagram of a bidirectional dialysis device during dialysis when the flow direction of the dialysate flowing through the second pump is opposite to the flow direction of the dialysate flowing through the first pump;

[0054] Fig.14 is a schematic diagram of pressure change of the dialyzer when the flow direction of the dialysate flowing through the second pump is the same as the flow direction of the dialysate flowing through the first pump;

[0055] Fig.15 is a schematic diagram of pressure change of the dialyzer when the flow direction of the dialysate flowing through the second pump is opposite to the flow direction of the dialysate flowing through the first pump;

[0056] Fig.16 It is a schematic diagram of the protein flushing when the liquid in the dialyzer enters the blood side from the dialysate side;

[0057] Fig.17 It is a schematic diagram of the protein being washed away when the liquid in the dialyzer enters the blood side from the dialysate side;

[0058] Fig.18 A schematic structural diagram of an implementation method of connecting a first dialyzer and a second dialyzer in series;

[0059] Fig.19This is a schematic structural diagram of another implementation method of connecting the first dialyzer and the second dialyzer in series.

[0060] Figures 1 to 10 The reference numerals in the drawings are:

[0061] 10-dialyzer; 20-dialysis machine; 30-blood pressure line; 40-dialysis fluid pressure line; 50-blood side; 60-dialysis fluid side; 70-protein; A0-blood inlet position point; B0-blood outlet position point;

[0062] Figures 11 to 19 The reference numerals in the drawings are:

[0063] 1-dialyzer; 11-first dialyzer; 111-blood inlet; 112-first dialysate inlet; 113-first dialysate outlet; 114-blood connection outlet; 12-second dialyzer; 121-blood outlet; 122-second dialysate inlet; 123-second dialysate outlet; 124-blood connection inlet; 13-connecting pipeline; 2-dialysis machine; 21-first dialysate pipeline; 22-second dialysate pipeline; 3-dialyzer; 3-dialyzer; 4-dialyzer; 5-dialyzer; 6-dialyzer; 7-dialyzer; 8-dialyzer; 9-dialyzer; 10-dialyzer; 11-dialysate pipeline; 12-dialysate pipeline; 13-dialysate pipeline; 14-dialysate pipeline; 15 -The third dialysate pipeline; 4-the fourth dialysate pipeline; 5-the first pump; 6-the second pump; 61-the push column; 71-the blood pressure line; 72-the dialysate pressure line in the first dialyzer; 73-the dialysate pressure line in the second dialyzer; 81-the blood side; 82-the dialysate side; 9-the protein; A-the blood inlet position point; B-the blood outlet position point of the first dialyzer; C-the blood inlet position point of the second dialyzer; D-the blood outlet position point. DETAILED DESCRIPTION

[0064] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0065] The core of the utility model is to provide a bidirectional dialysis device, which can improve the blood toxin removal effect without increasing the complexity of the connecting pipelines, can reduce the increase in the dialyzer transmembrane pressure caused by protein adsorption, and improve the protein removal effect in the dialyzer. Another core of the utility model is to provide a bidirectional dialysis system including the above-mentioned bidirectional dialysis device, which can improve the blood toxin removal effect without increasing the complexity of the connecting pipelines, can reduce the increase in the dialyzer transmembrane pressure caused by protein adsorption, and improve the protein removal effect in the dialyzer.

[0066] Please refer to Fig.11An embodiment of the utility model provides a bidirectional dialysis device, including a dialyzer 1, a third dialysis fluid pipeline 3, a fourth dialysis fluid pipeline 4, a first pump 5 and a second pump 6. The dialyzer 1 includes a blood inlet 111, a blood outlet 121, a first dialysate inlet 112, a first dialysate outlet 113, a second dialysate inlet 122 and a second dialysate outlet 123. The blood inlet 111 is arranged at the top of the dialyzer 1, and the blood outlet 121 is arranged at the bottom of the dialyzer 1. The blood inlet 111 and the blood outlet 121 are connected, and both are used to connect the blood pipeline respectively. Along the direction from the top to the bottom of the dialyzer 1, the first dialysate outlet 113, the first dialysate inlet 112, the second dialysate outlet 123 and the second dialysate inlet 122 are arranged in sequence. The first dialysate inlet 112 is connected to the first dialysate outlet 113, and the second dialysate inlet 122 is connected to the second dialysate outlet 123; the second dialysate inlet 122 is used to connect the first dialysate pipeline 21 of the dialysis machine 2. The first dialysate outlet 11 3 is used to connect the second dialysate pipeline 22 of the dialyzer 2, and the dialyzer 2 is used to control the flow rate of the dialysate transported by the first dialysate pipeline 21 and the second dialysate pipeline 22 to be the same through the pump control; the third dialysate pipeline 3 is connected to the first dialysate inlet 112; the fourth dialysate pipeline 4 is connected to the second dialysate outlet 123; the first pump 5 is connected to the third dialysate pipeline 3 and the fourth dialysate pipeline 4 respectively, and the first pump 5 is used to transport the dialysate at a uniform speed without being affected by the pressure, and the dialysate flow rate of the two ports of the first pump 5 is the same as the flow rate of the dialysate transported by the first dialysate pipeline 21 and the second dialysate pipeline 22; the second pump 6 is a reciprocating pump, which is connected in parallel with the first pump 5, and is connected to the third dialysate pipeline 3 and the fourth dialysate pipeline 4 respectively, and is used to periodically inhale or spit out the dialysate, and the dialysate flow rate of the two ports of the second pump 6 is the same.

[0067] When dialysis is needed, the blood line is connected to the blood inlet 111 and the blood outlet 121 respectively, the first dialysate line 21 is connected to the second dialysate inlet 122, the second dialysate line 22 is connected to the first dialysate outlet 113, the third dialysate line 3 is connected to the first dialysate inlet 112, the fourth dialysate line 4 is connected to the second dialysate outlet 123, and then the dialysis machine 2, the first pump 5 and the second pump 6 are started.

[0068] During the dialysis treatment, in the dialyzer 1, the blood flows in the opposite direction to the dialysate flow, the blood flows from top to bottom, and the dialysate flows from bottom to top. In addition, the blood flows inside the membrane filaments of the dialyzer 1 composed of semipermeable membranes, the membrane filaments can be cylindrical membrane filaments, and the dialysate flows outside the membrane filaments of the dialyzer 1. The blood and the dialysate do not directly contact each other when they flow, but due to the change of pressure inside and outside the membrane filaments, there will be mutual exchange between the liquid inside and outside the membrane filaments, that is, when the pressure on the blood side 81 is greater than the pressure on the dialysate side 82, the liquid on the blood side 81 will continue to flow into the dialysate side 82; conversely, when the pressure on the blood side 81 is less than the pressure on the dialysate side 82, the liquid on the dialysate side 82 will continue to flow into the blood.

[0069] For ease of understanding, ignoring the amount of dehydration, during the dialysis process, the blood flow rate entering the blood inlet 111 is equal to the blood flow rate flowing out of the blood outlet 121, that is, QBI=QBO. If the amount of dehydration is taken into account, QBO will actually be slightly smaller than QBI. At the same time, during the dialysis process, the dialysate flow rates of the first dialysate pipeline 21 and the second dialysate pipeline 22 can be made the same by controlling the pump through the dialyzer 2, that is, the flow rate of the dialysate entering the second dialysate inlet 122 is equal to the flow rate of the dialysate coming out of the first dialysate outlet 113, that is, QDI=QDO. This can be achieved through the existing functions of the existing dialysis machine 2, which will not be repeated here, and those skilled in the art can refer to the relevant technology.

[0070] In addition, the first pump 5 is used to transport the dialysate at a uniform speed without being affected by pressure, that is, the first pump 5 can control the dialysate passing through the first pump 5 to flow at a constant speed, and make the flow rate of the dialysate passing through the first pump 5 equal to the flow rate of the dialysate entering the second dialysate inlet 122 and the flow rate of the dialysate coming out of the first dialysate outlet 113, that is, Q3=Q4=QDI=QDO.

[0071] In addition, the second pump 6 is a reciprocating pump, and the driving column 61 of the second pump 6 can reciprocate at a uniform speed in the pump body at a certain frequency, so that the dialysate in the third dialysate pipeline 3 or the fourth dialysate pipeline 4 is uniformly sucked into the second pump 6 or discharged from the second pump 6, and the flow rate of the dialysate at the inlet and outlet of the second pump 6 is the same, that is, Q5=Q6.

[0072] Since the first pump 5 and the second pump 6 are connected in parallel between the third dialysate pipeline 3 and the fourth dialysate pipeline 4, the flow rate of the dialysate transported by the third dialysate pipeline 3 and the fourth dialysate pipeline 4 respectively is equal to the sum of the flow rates of the dialysate passing through the first pump 5 and the second pump 6, that is, Q1=Q3+Q5, Q2=Q4+Q6.

[0073] Furthermore, since the push column 61 of the second pump 6 reciprocates, during this process, the dialysate flowing through the second pump 6 periodically reverses direction, that is, during the reciprocating movement of the push column 61 of the second pump 6, the flow direction of the dialysate flowing through the second pump 6 can be periodically made the same as or opposite to the flow direction of the dialysate flowing through the first pump 5. If the flow rate of the dialysate flowing through the first pump 5 is positive, then when the flow direction of the dialysate flowing through the second pump 6 is the same as the flow direction of the dialysate flowing through the first pump 5, the flow rate of the dialysate flowing through the second pump 6 is positive, and when the flow direction of the dialysate flowing through the second pump 6 is opposite to the flow direction of the dialysate flowing through the first pump 5, the flow rate of the dialysate flowing through the second pump 6 is negative.

[0074] For example, the dialysis conditions are set as: QBI=QBO=200ml / min, QDI=Q3=Q4=QDO=500ml / min. Fig.12 As shown in FIG. 1 , when the flow direction of the dialysate flowing through the second pump 6 is the same as the flow direction of the dialysate flowing through the first pump 5, Q5=Q6=100 ml / min. At this time, Q1=Q3+Q5, Q1=600 ml / min, Q2=Q4+Q6, Q2=600 ml / min; Fig.13 As shown, when the flow direction of the dialysate flowing through the second pump 6 is opposite to the flow direction of the dialysate flowing through the first pump 5, Q5=Q6=-100ml / min. At this time, Q1=Q3+Q5, Q1=400ml / min, Q2=Q4+Q6, Q2=400ml / min.

[0075] When the flow direction of the dialysate flowing through the second pump 6 is the same as that of the dialysate flowing through the first pump 5, during the process of the push column 61 of the second pump 6 moving upward at a uniform speed of 100 ml / min, the dialysate pressure in the lower half of the dialyzer 1 decreases, and the liquid enters the dialysate side 82 from the blood side 81 at a speed of 100 ml / min; the liquid pressure in the upper half of the dialyzer 1 increases, and the liquid enters the blood side 81 from the dialysate side 82 at a speed of 100 ml / min. When the flow direction of the dialysate flowing through the second pump 6 is opposite to that of the dialysate flowing through the first pump 5, during the process of the push column 61 of the second pump 6 moving downward at a uniform speed of 100 ml / min, the dialysate pressure in the lower half of the dialyzer 1 increases, and the liquid enters the blood side 81 from the dialysate side 82 at a speed of 100 ml / min; the liquid pressure in the upper half of the dialyzer 1 decreases, and the liquid enters the dialysate side 82 from the blood side 81 at a speed of 100 ml / min. In the process that the push column 61 of the second pump 6 moves up and down periodically, the pressure of the dialyzer 1 changes periodically, and the above process is continuously repeated.

[0076] It can be seen that, under the joint action of the first pump 5 and the second pump 6, the flow rate Q2 of the dialysate entering the first dialysate inlet 112 can be periodically greater than or less than the flow rate QDO of the dialysate flowing out of the first dialysate outlet 113, and the flow rate QDI of the dialysate entering the second dialysate inlet 122 can be periodically less than or greater than the flow rate Q1 of the dialysate flowing out of the second dialysate outlet 123. In this way, the bidirectional dialysis device provided in this embodiment includes two processes during the dialysis process, please refer to Fig.14 , the first process is: the flow rate of the dialysate flowing through the second pump 6 is positive, the dialysate pressure in the lower half of the dialyzer 1 decreases, and the liquid enters the dialysate side 82 from the blood side 81 at a speed of Q1-QDI; the dialysate pressure in the upper half of the dialyzer 1 increases, and the liquid enters the blood side 81 from the dialysate side 82 at a speed of Q2-QDO. Please refer to Fig.15 In the second process, the flow rate of the dialysate flowing through the second pump 6 is negative, the dialysate pressure in the lower half of the dialyzer 1 rises, and the liquid enters the blood side 81 from the dialysate side 82 at a speed of QDI-Q1; the dialysate pressure in the upper half of the dialyzer 1 decreases, and the liquid enters the dialysate side 82 from the blood side 81 at a speed of QDO-Q2. As the second pump 6 periodically switches, the pressure in the dialyzer 1 changes periodically, and the above two processes are continuously cycled, that is, the first process and the second process are periodically switched, so that the dialysate alternately enters and exits the dialyzer 1, so that the protein 9 adsorbed on the inner surface of the inner membrane filament of the dialyzer 1 can be washed away, as shown in FIG. Fig.16 and Fig.17 As shown, the performance of the dialyzer 1 is ensured to be stable during the entire dialysis process, thereby avoiding the performance degradation of the dialyzer 1 due to protein 9 adsorption.

[0077] That is, the bidirectional dialysis device, by periodically changing the pressure on the dialysate side 82, strengthens the flushing effect of the dialysate side 82 liquid on the inner surface of the membrane filaments of the dialyzer 1 when entering the blood side 81, reduces the adsorption of protein 9 on the inner surface of the membrane filaments, improves the removal effect of the membrane filaments of the dialyzer 1, and increases the service life of the dialyzer 1, thereby avoiding a continuous increase in transmembrane pressure during the dialysis process.

[0078] In addition, for the first process mentioned above, the blood in the dialyzer 1 is diluted first and then concentrated, and the effect is equivalent to the pre-exchange therapy. For the second process mentioned above, the blood in the dialyzer 1 is concentrated first and then diluted, and the effect is equivalent to the post-exchange therapy. The first process and the second process are switched periodically, so that the dialysate alternately enters the dialyzer 1, which is equivalent to the dialyzer 1 periodically performing the pre-exchange therapy and the post-exchange therapy, which has an effect similar to the front and back simultaneous exchange therapy, and improves the toxin removal effect of the patient. For medical staff, the pipeline connection is similar to the pipeline connection of the hemodialysis treatment mode. It is only necessary to connect two dialysate connectors on the basis of the hemodialysis pipeline connection. The pipeline connection method is simple and convenient, avoiding the complex pipeline connection of the pre-exchange therapy, the post-exchange therapy, and the front and back simultaneous exchange therapy, reducing the processing time of medical staff and reducing treatment accidents caused by connection errors.

[0079] Further, for equipment, it is only necessary to add the third dialysate pipeline 3, the fourth dialysate pipeline 4, the first pump 5 and the second pump 6, so as to avoid complicated equipment design for the dialyzer 2 and reduce manufacturing costs. On the basis of improving the removal effect of the membrane filaments of the dialyzer 1 and avoiding the continuous increase in transmembrane pressure during the dialysis process, the effect of simultaneous replacement of the front and back can also be achieved. In addition, if traditional hemodialysis treatment is desired, it is only necessary to use a traditional dialyzer 1, so that the dialyzer 1 is only connected to two dialysate connectors of the first dialysate pipeline 21 and the second dialysate pipeline 22, so as to achieve the effect of traditional hemodialysis treatment.

[0080] It should be noted that the present embodiment does not specifically limit the specific structure of the first pump 5, and the first pump 5 may be a plunger pump or a peristaltic pump, as long as it can accurately control the flow rate without being affected by pressure changes. In addition, the present embodiment does not limit the specific structure of the second pump 6, and the second pump 6 may be a reciprocating pump, as long as it can periodically inhale or spit out liquid, and make the liquid volume and liquid flow rate at both ends of the inlet and outlet of the second pump 6 the same.

[0081] In addition, this embodiment does not limit the specific structure of the dialyzer 1, as long as it can meet the settings of the blood inlet 111, the blood outlet 121, the first dialysate inlet 112, the first dialysate outlet 113, the second dialysate inlet 122 and the second dialysate outlet 123, and realize the functions related to hemodialysis.

[0082] Considering the convenience of forming the structure of the dialyzer 1, in some embodiments, the dialyzer 1 includes a first dialyzer 11 and a second dialyzer 12 connected in series, the first dialyzer 11 includes a blood inlet 111, a first dialysate inlet 112 and a first dialysate outlet 113; the second dialyzer 12 includes a blood outlet 121, a second dialysate inlet 122 and a second dialysate outlet 123. It should be noted that the first dialyzer 11 and the second dialyzer 12 can be conventional dialyzers 1 in the prior art, which include four pipe openings, namely, a blood inlet 111, a blood outlet 121, a dialysate inlet and a dialysate outlet. In this embodiment, the first dialyzer 11 and the second dialyzer 12 are connected in series, so that the blood outlet 121 of the first dialyzer 11 is connected to the blood inlet 111 of the second dialyzer 12, so that the blood inlet 111 of the first dialyzer 11 serves as the blood inlet 111 of the overall dialyzer 1, and the blood outlet 121 of the second dialyzer 12 serves as the blood outlet 121 of the second dialyzer 12. The first dialyzer 11 and the second dialyzer 12 are connected in series so that the blood inlet 111 of the whole dialyzer 1 is connected to the blood outlet 121. In addition, the dialysate inlet and the dialysate outlet of the first dialyzer 11 are used as the first dialysate inlet 112 and the first dialysate outlet 113 of the whole dialyzer 1, and the dialysate inlet and the dialysate outlet of the second dialyzer 12 are used as the second dialysate inlet 122 and the second dialysate outlet 123 of the whole dialyzer 1. It can be seen that this scheme has little improvement on the conventional dialyzer 1 in the prior art, and the dialyzer 1 of the present application can be formed by connecting two conventional dialyzers 1 in series, so that the method of the present utility model can be quickly popularized.

[0083] It should be noted that the present embodiment does not limit the implementation method of the series connection of the first dialyzer 11 and the second dialyzer 12, as long as the series connection of the first dialyzer 11 and the second dialyzer 12 can be achieved.

[0084] Please refer to Fig.18In some embodiments, the bottom of the first dialyzer 11 is provided with a blood outflow through hole, and the top of the second dialyzer 12 is provided with a blood inflow through hole, and the bottom of the first dialyzer 11 is fixedly connected to the top of the second dialyzer 12 so that the blood outflow through hole is connected to the blood inflow through hole. That is to say, the present embodiment realizes the series connection of the first dialyzer 11 and the second dialyzer 12 by docking the blood outflow through hole with the blood inflow through hole, without a pipe mouth structure, and directly uses the through hole for blood to pass through to align and communicate, and the way to realize the series connection is simple, and only needs to align and abut the blood outflow through hole with the blood inflow through hole to make the first dialyzer 11 and the second dialyzer 12 fixedly connected. It is equivalent to removing an end cap from two conventional dialyzers 1 in the prior art, and then connecting the two conventional dialyzers 1 end to end to realize the series connection of the first dialyzer 11 and the second dialyzer 12, and the first dialyzer 11 and the second dialyzer 12 can be fixed by threaded connection, welding or other methods. This structure makes the structure of the overall dialyzer 1 compact.

[0085] Please refer to Fig.19 In other embodiments, the first dialyzer 11 includes a blood connection outlet 114, and the second dialyzer 12 includes a blood connection inlet 124, and the blood connection outlet 114 is connected to the blood connection inlet 124 through a connecting pipe. In other words, the first dialyzer 11 and the second dialyzer 12 in this embodiment are respectively provided with a nozzle structure (i.e., the blood connection outlet 114 and the blood connection inlet 124), and the two nozzle structures (i.e., the blood connection outlet 114 and the blood connection inlet 124) are connected through a connecting pipe, and the connection is convenient. It is equivalent to directly connecting the two conventional dialyzers 1 in the prior art by using a connecting pipe.

[0086] In addition to the above-mentioned bidirectional dialysis device, the embodiment of the utility model also provides a bidirectional dialysis system, which includes the bidirectional dialysis device and the dialysis machine 2 disclosed in any one of the above-mentioned embodiments, the dialysis machine 2 includes a first dialysis fluid pipeline 21 and a second dialysis fluid pipeline 22, and the dialysis machine 2 is used to control through a pump so that the flow rate of the dialysis fluid transported by the first dialysis fluid pipeline 21 and the second dialysis fluid pipeline 22 is the same, the first dialysis fluid pipeline 21 is connected to the second dialysis fluid inlet 122 of the bidirectional dialysis device, and the second dialysis fluid pipeline 22 is connected to the first dialysis fluid outlet 113 of the bidirectional dialysis device. For the structures and functions of other parts of the dialysis machine 2, please refer to the prior art, which will not be repeated herein.

[0087] The key point of this embodiment is to adopt the bidirectional dialysis device disclosed in any of the above embodiments, and utilize the first dialysate pipeline 21 and the second dialysate pipeline 22 of the dialysis machine to be connected to the second dialysate inlet 122 and the first dialysate outlet 113 of the bidirectional dialysis device respectively, so that the flow rate of the dialysate entering the second dialysate inlet 122 is the same as the flow rate of the dialysate coming out of the first dialysate outlet 113, thereby having the same beneficial effects as the above bidirectional dialysis device.

[0088] In addition, for ease of use, in some embodiments, a portion of the third dialysate line 3, a portion of the fourth dialysate line 4, the first pump 5 and the second pump 6 are integrated into the dialyzer 2. That is, in this embodiment, the first pump 5 and the second pump 6 are integrated into the dialyzer 2, so that the first pump 5 and the second pump 6 become a part of the dialyzer 2, so as to facilitate the overall control of the dialyzer 2, and to facilitate use. At the same time, the housing of the dialyzer 2 is used to support and protect the first pump 5 and the second pump 6. It can be understood that the third dialysate line 3 and the fourth dialysate line 4 play a role in connecting the first pump 5, the second pump 6 and the dialyzer 1. Therefore, a portion of the third dialysate line 3 and the fourth dialysate line 4 is located inside the dialyzer 2, and the other portion extends outside the dialyzer 2 to facilitate connection with the dialyzer 1. The first dialysate line 21 and the second dialysate line 22 can belong to the conventional structure of the conventional dialyzer 2 in the prior art, and are used to connect the dialyzer 1. That is to say, except for the third dialysate pipeline 3, the fourth dialysate pipeline 4, the first pump 5 and the second pump 6, the structures and functions of other parts of the dialyzer 2 can be the structures of the conventional dialyzer 2 in the prior art. In this way, the improvement of the dialyzer 2 is relatively small, and it is also convenient for rapid promotion and use.

[0089] In addition, it should be noted that the present embodiment does not limit the specific materials of the first dialysate pipeline 21 , the second dialysate pipeline 22 , the third dialysate pipeline 3 , and the fourth dialysate pipeline 4 .

[0090] In some embodiments, the first dialysate pipeline 21, the second dialysate pipeline 22, the third dialysate pipeline 3 and the fourth dialysate pipeline 4 are hard silicone pipelines, respectively. Hard silicone pipelines have good biocompatibility.

[0091] In addition, in some embodiments, the two ports of the first pump 5 are respectively provided with first flow rate detection devices, which are used to detect the flow rates of the two ports of the first pump 5, so as to feedback control the flow rate of the first pump 5. That is to say, in this embodiment, by respectively providing the first flow rate detection devices at the two ports of the first pump 5, the first flow rate detection devices are used to monitor the flow rate of the liquid at both ends of the first pump 5 in real time, so as to feedback control the flow rate of the first pump 5 when the flow rates at both ends of the first pump 5 are different, so as to ensure that the flow rates at the two ports of the first pump 5 are always the same.

[0092] In some embodiments, the two ports of the second pump 6 are respectively provided with second flow rate detection devices, which are used to detect the flow rate of the two ports of the second pump 6, so as to feedback control the flow rate of the second pump 6. That is to say, in this embodiment, by respectively providing the second flow rate detection devices at the two ports of the second pump 6, the second flow rate detection devices are used to monitor the liquid flow rate at both ends of the second pump 6 in real time, so as to feedback control the flow rate of the second pump 6 when the flow rates at both ends of the second pump 6 are different, so as to ensure that the flow rates at the two ports of the second pump 6 are always the same.

[0093] In some embodiments, the first dialysate pipeline 21 is provided with a third flow rate detection device, which is used to detect the flow rate of the first dialysate pipeline 21, so that the dialyzer 2 performs feedback control on the flow rate of the first dialysate pipeline 21. That is, in this embodiment, by providing the third flow rate detection device in the first dialysate pipeline 21, the third flow rate detection device is used to monitor the liquid flow rate of the first dialysate pipeline 21 in real time, so that when the flow rate of the first dialysate pipeline 21 does not meet the requirements, the flow rate of the first dialysate pipeline 21 is feedback controlled to ensure that the flow rate of the first dialysate pipeline 21 meets the requirements.

[0094] In some embodiments, the second dialysate pipeline 22 is provided with a fourth flow rate detection device, which is used to detect the flow rate of the second dialysate pipeline 22, so that the dialyzer 2 performs feedback control on the flow rate of the second dialysate pipeline 22. That is, in this embodiment, by providing the fourth flow rate detection device in the second dialysate pipeline 22, the fourth flow rate detection device is used to monitor the liquid flow rate of the second dialysate pipeline 22 in real time, so that when the flow rate of the second dialysate pipeline 22 does not meet the requirements, the flow rate of the second dialysate pipeline 22 is feedback controlled to ensure that the flow rate of the second dialysate pipeline 22 meets the requirements.

[0095] Furthermore, in some embodiments, pressure monitoring devices are respectively provided on the first dialysate line 21, the second dialysate line 22, the third dialysate line 3 and the fourth dialysate line 4 to monitor the transmembrane pressure of the dialyzer 1 to avoid damage to the dialyzer 1 due to excessive transmembrane pressure.

[0096] It should also be noted that, in this specification, relational terms such as first and second, etc. are merely used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations.

[0097] The various embodiments in this specification are described in a progressive manner, and each embodiment focuses on the differences from other embodiments. The same or similar parts between the various embodiments can be referenced to each other.

[0098] The bidirectional dialysis device and bidirectional dialysis system provided by the utility model are introduced in detail above. The principle and implementation mode of the utility model are described in detail using specific examples herein, and the description of the above embodiments is only used to help understand the method and core idea of ​​the utility model. It should be pointed out that for ordinary technicians in this technical field, without departing from the principle of the utility model, the utility model can also be improved and modified, and these improvements and modifications also fall within the scope of protection of the utility model.

Claims

1. A two-way dialysis device, characterized in that: include: A dialyzer (1), comprising a blood inlet (111), a blood outlet (121), a first dialysate inlet (112), a first dialysate outlet (113), a second dialysate inlet (122) and a second dialysate outlet (123), wherein the blood inlet (111) is arranged at the top of the dialyzer (1), and the blood outlet (121) is arranged at the bottom of the dialyzer (1), the blood inlet (111) and the blood outlet (121) are connected, and both are used to connect blood pipelines, and along the direction from the top to the bottom of the dialyzer (1), the first dialysate outlet (113), the first dialysate inlet (112), the second dialysate outlet (123) and the second dialysate inlet (122) are arranged in sequence, and the first dialysate inlet (112) is connected to the first dialysate outlet (113), and the second dialysate inlet (122) is connected to the second dialysate outlet (123); The second dialysate inlet (122) is used to connect to the first dialysate pipeline (21) of the dialyzer (2), and the first dialysate outlet (113) is used to connect to the second dialysate pipeline (22) of the dialyzer (2), and the dialyzer (2) is used to control the flow rate of the dialysate transported by the first dialysate pipeline (21) and the second dialysate pipeline (22) by means of a pump so that the flow rate of the dialysate transported by the first dialysate pipeline (21) and the second dialysate pipeline (22) are the same; A third dialysate pipeline (3) connected to the first dialysate inlet (112); a fourth dialysate pipeline (4), connected to the second dialysate outlet (123); a first pump (5), connected to the third dialysate pipeline (3) and the fourth dialysate pipeline (4), respectively, for conveying the dialysate at a uniform speed without being affected by pressure, and making the dialysate flow rate at the two ports of the first pump (5) the same as the flow rate of the dialysate conveyed by the first dialysate pipeline (21) and the second dialysate pipeline (22); The second pump (6) is a reciprocating pump, connected in parallel with the first pump (5), and connected to the third dialysate pipeline (3) and the fourth dialysate pipeline (4) respectively, for periodically inhaling or discharging the dialysate, and the dialysate flow rate at the two ports of the second pump (6) is the same.

2. The two-way dialysis device according to claim 1, characterized in that: The dialyzer (1) comprises a first dialyzer (11) and a second dialyzer (12) connected in series, wherein the first dialyzer (11) comprises the blood inlet (111), the first dialysate inlet (112) and the first dialysate outlet (113); The second dialyzer (12) comprises the blood outlet (121), the second dialysate inlet (122) and the second dialysate outlet (123).

3. The two-way dialysis device according to claim 2, characterized in that: A blood outflow through hole is provided at the bottom of the first dialyzer (11), and a blood inflow through hole is provided at the top of the second dialyzer (12). The bottom end of the first dialyzer (11) is fixedly connected to the top end of the second dialyzer (12) so that the blood outflow through hole is connected to the blood inflow through hole.

4. The two-way dialysis device according to claim 2, characterized in that: The first dialyzer (11) comprises a blood connection outlet (114), and the second dialyzer (12) comprises a blood connection inlet (124), and the blood connection outlet (114) is connected to the blood connection inlet (124) via a connecting pipe (13).

5. A two-way dialysis system, characterized in that: include: The bidirectional dialysis device according to any one of claims 1 to 4; The dialysis machine comprises a first dialysate pipeline (21) and a second dialysate pipeline (22), which are used to control the flow rate of the dialysate transported by the first dialysate pipeline (21) and the second dialysate pipeline (22) to be the same through pump control, wherein the first dialysate pipeline (21) is connected to the second dialysate inlet (122) of the bidirectional dialysis device, and the second dialysate pipeline (22) is connected to the first dialysate outlet (113) of the bidirectional dialysis device.

6. The two-way dialysis system according to claim 5, characterized in that: A portion of the third dialysate pipeline (3), a portion of the fourth dialysate pipeline (4), the first pump (5) and the second pump (6) are integrated inside the dialysis machine (2).

7. The two-way dialysis system according to claim 5, characterized in that: The first dialysate pipeline (21), the second dialysate pipeline (22), the third dialysate pipeline (3) and the fourth dialysate pipeline (4) are respectively hard silicone pipelines.

8. The two-way dialysis system according to any one of claims 5 to 7, characterized in that: The two ports of the first pump (5) are respectively provided with first flow rate detection devices for detecting the flow rates of the two ports of the first pump (5) so as to perform feedback control on the flow rate of the first pump (5).

9. The two-way dialysis system according to any one of claims 5 to 7, characterized in that: The two ports of the second pump (6) are respectively provided with second flow rate detection devices for detecting the flow rates of the two ports of the second pump (6) so as to perform feedback control on the flow rate of the second pump (6).

10. The two-way dialysis system according to any one of claims 5 to 7, characterized in that: The first dialysate pipeline (21) is provided with a third flow rate detection device, which is used to detect the flow rate of the first dialysate pipeline (21), so that the dialysis machine (2) can perform feedback control on the flow rate of the first dialysate pipeline (21); The second dialysate pipeline (22) is provided with a fourth flow rate detection device, which is used to detect the flow rate of the second dialysate pipeline (22), so that the dialysis machine (2) can perform feedback control on the flow rate of the second dialysate pipeline (22).

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