Filter plate cleaning device for nucleic acid synthesis

Abstract

The utility model discloses a filter plate cleaning device for nucleic acid synthesis, which comprises an outer shell, a porous filter plate is horizontally mounted in the middle of the inside of the outer shell, and a plurality of vertically through filter holes are formed on the surface of the porous filter plate in an array manner; a base body is horizontally installed on the upper portion in the outer shell, an air chamber is formed in the base body, a plurality of air blowing pipes are arranged at the bottom end of the base body in a downward protruding mode, and air blowing channels penetrating up and down are formed in the air blowing pipes. A lifting air cylinder and an air pump part are arranged at the top end of the outer shell, the output end of the lifting air cylinder downwards penetrates through the surface of the outer shell and then is connected to the upper end of the base body, and the air pump part is connected with the air chamber of the base body through an air pipe. The air blowing device is simple in structure and reasonable in design, the air blowing pipes correspond to the filtering holes in the surface of the porous filtering plate, the air pump part is started to inject compressed air into the air chamber, the compressed air blows the filtering holes through the air blowing channels, therefore, the purpose of cleaning blockages in the filtering holes is achieved, and the cleaning effect is good.

Description

Technical Field

[0001] The utility model relates to the technical field of nucleic acid synthesis, in particular to a filter plate cleaning device used for nucleic acid synthesis. Background Art

[0002] In biochemical and pharmaceutical experiments such as protein purification, nucleic acid preparation, and new drug screening, microporous filter plates are often used for filtration cleaning or filtration recovery, especially in the processes of solid phase extraction, component purification, magnetic bead analysis, or product recovery.

[0003] For example, the prior art CN207012654U discloses a porous filter plate, including a fixing frame, on which a plurality of sample holes are provided, and the bottom of the sample holes are connected to a plurality of filter parts through a detachable structure, and the filter parts include a plurality of strip filter holes that penetrate the thickness direction of the filter part and are distributed along the circumferential direction, and a guide hole that is an integral structure with the filter part is provided below the strip filter holes, and telescopic handles are movably connected on both sides of the fixing frame.

[0004] When the above-mentioned prior art is applied, the inside of the filter hole may be clogged due to excessive use of the filter plate, affecting the subsequent filtration cleaning or filtration recovery work. The filter holes on the above-mentioned filter part are strip-shaped and have a certain depth, which makes it impossible to complete the cleaning of the filter holes during the preliminary preparation of the filter plate, making cleaning difficult and affecting subsequent use. Utility Model Content

[0005] The purpose of the utility model is to provide a filter plate cleaning device for nucleic acid synthesis to solve the problems mentioned in the above background technology.

[0006] To achieve the above purpose, the utility model adopts the following contents:

[0007] The utility model provides a filter plate cleaning device for nucleic acid synthesis, which comprises an outer shell, the interior of the outer shell is hollow, a porous filter plate is horizontally installed in the middle of the inner part of the outer shell, and a surface array of the porous filter plate is formed with a plurality of filter holes that pass through from top to bottom; a base is horizontally installed in the upper inner part of the outer shell, an air chamber is formed in the inner part of the base, a plurality of air blowing pipes are protruding downward from the bottom end of the base, the number and position of the plurality of air blowing pipes correspond to the number and position of the plurality of filter holes, an air blowing channel that passes through from top to bottom is formed in the air blowing pipe, and the top end of the air blowing channel is communicated with the air chamber; a lifting cylinder and an air pump component are arranged at the top end of the outer shell, the output end of the lifting cylinder passes through the outer shell surface downward and is connected to the upper end of the base, the lifting cylinder realizes the up and down movement of the base, and the air pump component is connected to the air chamber of the base through an air pipe.

[0008] According to a filter plate cleaning device for nucleic acid synthesis provided by the utility model, a positioning plate is also horizontally arranged inside the outer shell, and the positioning plate is located between the plurality of air blowing tubes and the porous filter plate. The surface of the positioning plate is formed with a plurality of guide holes, and the number and position of the plurality of guide holes correspond to the number and position of the plurality of air blowing tubes. By designing the positioning plate and providing a plurality of guide holes on the positioning plate, it is ensured that during the process of the lifting cylinder driving the base to move up and down, the plurality of air blowing tubes can smoothly move up and down in a straight line, thereby ensuring that the plurality of air blowing tubes can correspond one by one to the filter holes on the porous filter plate, thereby achieving the air blowing cleaning work of the filter holes.

[0009] Furthermore, in the initial state, the ends of the plurality of air blowing tubes are inserted into the plurality of guide holes, so that the situation that the plurality of air blowing tubes cannot be aligned with the plurality of guide holes at the beginning can be avoided, and the time for alignment can be reduced.

[0010] Furthermore, the positioning plate is movably mounted inside the outer shell; both sides of the positioning plate are formed with a lower edge extending downward, the outer wall of the lower edge can abut against the inner wall of the outer shell, a mounting seat is arranged on the outer wall of the outer shell, a nut seat is arranged on the surface of the mounting seat, a horizontal fastening screw is threadedly connected to the nut seat, and the head end of the fastening screw passes through the side wall of the outer shell inward and acts on the surface of the lower edge. Designing the positioning plate to be movably mounted inside the outer shell is not only convenient for installation, but also conducive to the subsequent disassembly and replacement of the positioning plate.

[0011] According to the filter plate cleaning device for nucleic acid synthesis provided by the utility model, a groove is formed inwardly on the inner side of the bottom end of the air blowing tube. Through the design of the concave groove, it is ensured that after the end of the air blowing tube contacts the surface of the porous filter plate, the filter holes are covered by the groove, which can improve the sealing effect between the air blowing channel and the filter holes, thereby ensuring a good air blowing effect.

[0012] According to the filter plate cleaning device for nucleic acid synthesis provided by the utility model, a feed pipe opening is arranged on one side outer wall of the outer shell, and a discharge pipe opening is arranged on the other side outer wall of the outer shell, the feed pipe opening and the discharge pipe opening are both communicated with the interior of the outer shell, and the feed pipe opening is arranged at a position higher than the position of the porous filter plate, and the discharge pipe opening is arranged near the bottom end of the outer shell. In this way, the product can be fed into the outer shell through the feed pipe opening, filtered by the porous filter plate, and then flow out from the discharge pipe opening, which is very convenient to use.

[0013] According to the filter plate cleaning device for nucleic acid synthesis provided by the utility model, an openable door is provided on the upper back of the outer shell, which is convenient for installing the internal components of the outer shell and also convenient for operators to understand the situation inside the outer shell from this position when necessary.

[0014] Compared with the prior art, the utility model has the following technical effects: the utility model has a simple structure and a reasonable design; the filtering effect on the product is achieved by the porous filter plate inside the outer shell, and after the filtering is completed, the base can be driven downward by the lifting cylinder, thereby driving a number of blowing pipes on the base to move downward until the number of blowing pipes correspond to the filter holes on the surface of the porous filter plate. At this time, the air pump is started to inject compressed gas into the air chamber, and the compressed gas then blows the filter holes through the blowing channel, thereby achieving the purpose of cleaning the blockages inside the filter holes, and the cleaning effect is good. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] The specific implementation of the utility model is further described in detail below with reference to the accompanying drawings.

[0016] Figure 1 It is a rear view schematic diagram of a filter plate cleaning device for nucleic acid synthesis according to an embodiment of the utility model;

[0017] Figure 2 This is a schematic diagram of the related structures of a base, an air blowing tube, a positioning plate and a porous filter plate in a filter plate cleaning device for nucleic acid synthesis according to an embodiment of the utility model;

[0018] Figure 3 It is a cross-sectional structural schematic diagram of a base body, an air blowing tube, a positioning plate and a porous filter plate in a filter plate cleaning device for nucleic acid synthesis according to an embodiment of the utility model;

[0019] 1-outer shell, 2-porous filter plate, 3-base, 4-blowing pipe, 5-lifting cylinder, 6-air pump part, 7-positioning plate, 8-mounting seat, 11-feed pipe opening, 12-discharge pipe opening, 13-door, 21-filter hole, 31-air chamber, 41-blowing channel, 42-groove, 71-guide hole, 72-lower edge, 81-nut seat, 82-fastening screw. DETAILED DESCRIPTION

[0020] In order to explain the present invention more clearly, the present invention is further described below in conjunction with preferred embodiments. Those skilled in the art should understand that the following specific description is illustrative rather than restrictive, and should not be used to limit the scope of protection of the present invention.

[0021] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or an indirect connection through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to the specific circumstances.

[0022] See also Figures 1 to 3 As shown. The embodiment of the utility model proposes a filter plate cleaning device for nucleic acid synthesis, comprising an outer shell 1, the interior of the outer shell is hollow, a porous filter plate 2 is horizontally installed in the middle of the inner part of the outer shell 1, and a plurality of filter holes 21 are formed in the surface array of the porous filter plate 2 and are connected vertically; a base 3 is horizontally installed in the upper part of the inner part of the outer shell 1, and an air chamber 31 is formed in the inner part of the base 3, and a plurality of air blowing pipes 4 are protruding downward from the bottom end of the base 3, and the number and position of the plurality of air blowing pipes 4 correspond to the number and position of the plurality of filter holes 21, and an air blowing channel 41 is formed in the inner part of the air blowing pipe 4 and is connected to the air chamber 31 at the top of the air blowing channel 41; a lifting cylinder 5 and an air pump 6 are arranged at the top of the outer shell 1, and the output end of the lifting cylinder 5 penetrates the surface of the outer shell 1 downward and is connected to the upper end of the base 3, and the lifting cylinder 5 realizes the up and down movement of the base 3, and the air pump 6 is connected to the air chamber 31 of the base 3 through a soft air pipe (not specifically shown, but does not affect other technical personnel to understand this solution).

[0023] When the above-mentioned filtering device is in use: the base 3 is driven to move downward by lifting the cylinder 5, thereby driving the multiple blowing pipes 4 on the base 3 to move downward synchronously, until the multiple blowing pipes 4 correspond to the filter holes 21 on the surface of the porous filter plate 2 one by one, and then the air pump part 6 is started to inject compressed gas into the air chamber 31, and the compressed gas is then blown downward to the filter holes 21 through the blowing channel 41 in the blowing pipe 4, so as to achieve the purpose of cleaning the blockage inside the filter hole, and the cleaning effect is good.

[0024] In other embodiments, a positioning plate 7 is also horizontally arranged inside the outer shell 1, and the positioning plate 7 is located between the plurality of air blowing pipes 4 and the porous filter plate 2. A plurality of guide holes 71 are formed on the surface of the positioning plate 7, and the number and position of the plurality of guide holes 71 correspond to the number and position of the plurality of air blowing pipes 4. By designing the positioning plate and providing a plurality of guide holes on the positioning plate, the guide holes are used to limit the lateral deviation of the air blowing pipes, so as to ensure that when the lifting cylinder drives the base to move up and down, the plurality of air blowing pipes can smoothly move up and down in a straight line, thereby ensuring that the plurality of air blowing pipes can correspond to the filter holes on the porous filter plate one by one, thereby achieving the air blowing cleaning work of the filter holes.

[0025] It should be noted that, in the initial state, the ends of the plurality of air blowing tubes 4 are inserted into the plurality of guide holes 71. This can avoid the situation that the plurality of air blowing tubes cannot be aligned with the plurality of guide holes at the beginning, thereby reducing the time for alignment.

[0026] Among them, the positioning plate 7 is movably installed inside the outer shell 1; the two sides of the positioning plate 7 are formed with a lower edge 72 extending downward, and the outer wall of the lower edge 72 can abut against the inner wall of the outer shell 1. A mounting seat 8 is arranged on the outer wall of the outer shell 1, and a nut seat 81 is arranged on the surface of the mounting seat 8. A horizontal fastening screw 82 is threadedly connected to the nut seat 81. The head end of the fastening screw 82 passes through the side wall of the outer shell 1 inward and acts on the surface of the lower edge 72. In this way, the fastening screws 82 on both sides are used to fix the positioning plate 7, so that the positioning plate is fixed at a certain height inside the outer shell. Designing the positioning plate to be movably installed inside the outer shell is not only convenient for installation, but also conducive to the subsequent disassembly and replacement of the positioning plate.

[0027] In other embodiments, a groove 42 is formed inwardly on the inner side of the bottom end of the air blowing pipe 4. The recessed groove design ensures that after the end of the air blowing pipe contacts the surface of the porous filter plate, the filter holes are covered by the groove, which can improve the sealing effect between the air blowing channel and the filter holes, thereby ensuring a good air blowing effect.

[0028] In other embodiments, a feed pipe opening 11 is provided on one side outer wall of the outer shell 1, and a discharge pipe opening 12 is provided on the other side outer wall of the outer shell 1, and both the feed pipe opening 11 and the discharge pipe opening 12 are communicated with the interior of the outer shell 1, and the feed pipe opening 11 is arranged at a position higher than the position of the porous filter plate 2, and the discharge pipe opening 12 is arranged near the bottom end of the outer shell 1. In this way, the product can be fed into the outer shell through the feed pipe opening, and then flow out from the discharge pipe opening after being filtered by the porous filter plate, which is very convenient to use.

[0029] In other embodiments, an openable door 13 may be provided on the upper back of the outer shell 1. The door is a conventional hinged opening and closing design. The opening and closing door is convenient for installing the internal components of the outer shell and, when necessary, it is convenient for the operator to understand the situation inside the outer shell from this position.

[0030] Obviously, the above embodiments of the present invention are merely examples for clearly illustrating the present invention, and are not limitations on the implementation methods of the present invention. For ordinary technicians in the relevant field, other different forms of changes or modifications can be made based on the above description. It is impossible to list all the implementation methods here. All obvious changes or modifications derived from the technical solution of the present invention are still within the scope of protection of the present invention.

Claims

1. A filter plate cleaning device for nucleic acid synthesis, characterized in that: It comprises an outer shell, the interior of which is hollow, a porous filter plate is horizontally installed in the middle of the interior of the outer shell, a surface array of the porous filter plate is formed with a number of filter holes that pass through from top to bottom; a base is horizontally installed in the upper interior of the outer shell, an air chamber is formed inside the base, a number of blowing pipes are protruding downward from the bottom end of the base, the number and position of the blowing pipes correspond to the number and position of the filter holes, a blowing channel that passes through from top to bottom is formed inside the blowing pipe, and the top of the blowing channel is communicated with the air chamber; a lifting cylinder and an air pump component are arranged at the top of the outer shell, the output end of the lifting cylinder passes downward through the surface of the outer shell and is connected to the upper end of the base, the up and down movement of the base is realized by the lifting cylinder, and the air pump component is connected to the air chamber of the base through an air pipe.

2. A filter plate cleaning device for nucleic acid synthesis according to claim 1, characterized in that: A positioning plate is also horizontally arranged inside the outer shell, and the positioning plate is located between the plurality of air blowing pipes and the porous filter plate. A plurality of guide holes are formed on the surface of the positioning plate, and the number and positions of the plurality of guide holes correspond to the number and positions of the plurality of air blowing pipes.

3. A filter plate cleaning device for nucleic acid synthesis according to claim 2, characterized in that: In an initial state, the ends of the plurality of air blowing pipes are inserted into the plurality of guide holes.

4. A filter plate cleaning device for nucleic acid synthesis according to claim 2, characterized in that: The positioning plate is movably installed inside the outer shell; downwardly extending lower edges are formed on both sides of the positioning plate, and the outer wall of the lower edge can abut against the inner wall of the outer shell; a mounting seat is arranged on the outer side wall of the outer shell, and a nut seat is arranged on the surface of the mounting seat, and a horizontal fastening screw is threadedly connected to the nut seat, and the head end of the fastening screw passes inward through the side wall of the outer shell and acts on the surface of the lower edge.

5. A filter plate cleaning device for nucleic acid synthesis according to claim 1, characterized in that: A groove is formed inwardly on the inner side of the bottom end of the air blowing pipe.

6. A filter plate cleaning device for nucleic acid synthesis according to claim 1, characterized in that: A feed pipe opening is arranged on one side outer wall of the outer shell, and a discharge pipe opening is arranged on the other side outer wall of the outer shell. Both the feed pipe opening and the discharge pipe opening are communicated with the interior of the outer shell, and the feed pipe opening is arranged at a position higher than the position of the porous filter plate, and the discharge pipe opening is arranged close to the bottom end of the outer shell.

7. A filter plate cleaning device for nucleic acid synthesis according to claim 1, characterized in that: An openable door is arranged on the upper back side of the outer shell.

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