Centrifugal tube for manufacturing cell wax block and centrifugal tube kit
By designing a removable connected centrifuge tube and a disposable extraction spoon, the problems of cell loss and agglomerate fragmentation during the precipitate extraction process in cell wax block production are solved, and the extraction efficiency and accuracy of slices are improved.
Patent Information
- Application Number
- CN202421585953.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-05
- Publication Date
- 2025-05-06
- Estimated Expiration
- 2034-07-05
AI Technical Summary
In the prior art, when making cell wax blocks, the height of the centrifuge tube causes cell loss and waste, and the cell aggregation is prone to breaking under the action of fixative, affecting the accuracy of subsequent sections.
A removable connected centrifugal tube is designed, and the tube body is composed of multiple second tube sections. The staff can adjust the tube body height according to the height of the sediment to reduce the distance of extracting the sediment. In addition, a disposable extraction spoon is provided instead of tweezers to reduce the risk of crushing of aggregates during the acquisition process.
Through the adjustable centrifuge tube design, cell loss and waste are reduced and the efficiency of pellet extraction is improved. The use of a disposable extraction spoon avoids agglomerate breakage, ensuring the integrity and accuracy of subsequent sections.
Smart Images

Figure CN222829677U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the field of medical instruments, in particular to a centrifuge tube and a centrifuge tube kit for making cell wax blocks. Background Art
[0002] Cytological wax blocks made of cell agglutinates have the advantages of long-term storage and repeated sectioning. Cell wax blocks can be used for comparison of cell smears, immunohistochemistry and molecular testing, which is beneficial for cytopathological diagnosis. High-quality cell agglutinates can completely preserve the basic information of cell substances, which determines the accuracy of cytological diagnosis.
[0003] At present, the centrifugal sedimentation method is the most commonly used and simplest method for making cell wax blocks. The body fluid specimens are centrifuged at medium speed after standing, and the supernatant is discarded. Chemical reagents are then added and centrifuged to obtain clumped cell precipitates, which are then clamped with tweezers onto embedding paper for subsequent processing. However, for specimens with very little sediment, because the centrifuge tube has a certain height, the process of clamping the sediment from the centrifuge tube to the embedding paper with tweezers often causes cell loss and waste. In addition, because the cells are agglutinated at the bottom of the tube under the action of the fixative and the substance formed will harden, the cell agglutinates are easily broken during clamping, which may result in the diseased cells not being shown on the subsequent sections. Utility Model Content
[0004] The purpose of the utility model is to provide a centrifuge tube and a centrifuge tube kit for making cell wax blocks, which can solve the technical problems mentioned in the above background technology.
[0005] In order to solve the above technical problems, the technical solution adopted by the utility model is:
[0006] A centrifuge tube for making cell wax blocks comprises a first tube section, a plurality of second tube sections and a tube cover, wherein the plurality of second tube sections are detachably connected in sequence to form a tube body, and the first tube section and the tube cover are detachably mounted at both ends of the tube body;
[0007] One end of the first pipe section connected to the pipe body is open, and the other end is closed, and both ends of the second pipe section are open;
[0008] A sealing member is arranged between the first pipe section and the second pipe section, between two adjacent second pipe sections, and between the pipe cover and the second pipe section.
[0009] Furthermore, a first threaded hole is formed on the inner hole wall of the open end of the first pipe section;
[0010] The second pipe section includes a first pipe wall and a first tubular connecting piece arranged at one end of the first pipe wall, and the first tubular connecting piece is matched with the first threaded hole.
[0011] Furthermore, a first threaded hole is also formed on the inner hole wall of the first tube wall at one end away from the first tubular connecting piece, and two adjacent second tube sections are connected through the first tubular connecting piece and the first threaded hole.
[0012] Furthermore, the sealing member is a sealing ring, and the sealing member is sleeved on the first tubular connecting member.
[0013] Furthermore, an outer peripheral wall of one of the second pipe sections is provided with an external thread, and an inner hole wall of the pipe cover is provided with an internal thread matching the external thread;
[0014] The seal is installed inside the tube cover.
[0015] Furthermore, the first pipe section includes a second pipe wall and a pipe tail piece, a second tubular connecting piece is provided at one end of the pipe tail piece close to the second pipe wall, a sealing piece is also sleeved on the second tubular connecting piece, and a second threaded hole for installing the second tubular connecting piece is opened on the inner hole wall of one end of the second pipe wall close to the pipe tail piece.
[0016] A centrifuge tube kit, comprising:
[0017] Any of the above centrifuge tubes;
[0018] The disposable extraction spoon is used to pick up cell aggregates in a centrifuge tube, and comprises a spoon head and a spoon handle, wherein the spoon head and the spoon handle are fixedly connected, and an end of the spoon head away from the spoon handle is in contact with the inner wall of the closed section of the first tube section.
[0019] Compared with the prior art, the embodiments of the present invention have at least the following advantages or beneficial effects:
[0020] 1. The utility model provides a centrifuge tube for making cell wax blocks, wherein the tube body is composed of a plurality of second tube sections that are detachably connected. The staff can remove the second tube section above the sediment according to the height of the sediment, thereby reducing the blind spot of vision when extracting the sediment and shortening the distance for extracting the sediment, thereby facilitating the staff to take the sediment out of the centrifuge tube.
[0021] 2. The disposable extraction spoon provided by the utility model replaces tweezers to obtain the agglutinate in the centrifuge tube, thereby avoiding the agglutinate from being broken by force during the acquisition process; the disposable extraction spoon can fit the bottom of the centrifuge tube, greatly reducing the loss of the agglutinate. BRIEF DESCRIPTION OF THE DRAWINGS
[0022] In order to more clearly illustrate the technical solutions of the embodiments of the utility model, the drawings required for use in the embodiments will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the utility model and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other relevant drawings can be obtained based on these drawings without paying creative work.
[0023] Figure 1 A schematic diagram of the structure of a centrifuge tube for making cell wax blocks provided by the utility model;
[0024] Figure 2 A schematic diagram of the explosion structure of a centrifuge tube for making cell wax blocks provided by the utility model;
[0025] Figure 3 A schematic diagram of the structure of the second pipe section provided by the utility model;
[0026] Figure 4 A schematic diagram of the structure of the first pipe section provided by the utility model;
[0027] Figure 5 This is a structural schematic diagram of the disposable extraction spoon provided by the utility model.
[0028] Icon: 100-first tube section; 101-first threaded hole; 103-second tube wall; 105-tube tail piece; 107-second tubular connector; 109-second threaded hole; 110-second tube section; 111-tube body; 113-first tubular connector; 115-first tube wall; 130-tube cover; 150-seal; 200-disposable extraction spoon; 201-spoon head; 203-spoon handle. DETAILED DESCRIPTION
[0029] In order to make the purpose, technical scheme and advantages of the embodiments of the utility model clearer, the technical scheme in the embodiments of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are part of the embodiments of the utility model, not all of the embodiments. Generally, the components of the embodiments of the utility model described and shown in the drawings here can be arranged and designed in various different configurations.
[0030] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the present invention to be protected, but merely represents selected embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0031] Please refer to Figures 1 to 3As shown, a centrifuge tube for making cell wax blocks includes a first tube section 100, a plurality of second tube sections 110 and a tube cover 130. Both ends of the second tube section 110 are open, and the plurality of second tube sections 110 are detachably connected in sequence to form a tube body 111. One end of the first tube section 100 connected to the tube body 111 is open, and the other end is closed. The internal space of the tube body 111 is connected to the internal space of the first tube section 100 to form a centrifuge chamber for holding body fluid specimens. The tube cover 130 is detachably mounted on one end of the tube body 111 away from the first tube section 100, and is used to close the centrifuge chamber.
[0032] In addition, a seal 150 is provided between the first tube section 100 and the second tube section 110, between two adjacent second tube sections 110, and between the tube cover 130 and the second tube section 110. When the centrifuge tube is installed, the first tube section 100 and the second tube section 110 squeeze the seal 150 therebetween, the two adjacent second tube sections 110 squeeze the seal 150 therebetween, and the tube cover 130 and the second tube section 110 squeeze the seal 150 therebetween, so that multiple joints are in a sealed state. At this time, the centrifuge tube is in a sealed state to prevent the body fluid specimen in the centrifuge tube from leaking out.
[0033] After the staff completes the centrifugation work using the centrifuge tube provided in the present application, they can remove the corresponding second tube section 110 according to the height of the agglomerate in the centrifuge tube, thereby lowering the height of the centrifuge tube and reducing the blind spot of vision when extracting the precipitate, making it easier for the staff to remove the precipitate from the centrifuge tube.
[0034] Please refer to Figure 2 As shown, the first pipe section 100 and the second pipe section 110 are connected by threads. Specifically, the first pipe section 100 is provided with a first threaded hole 101 on the inner hole wall of the open end. The second pipe section 110 includes a first pipe wall 115 and a first tubular connector 113 disposed at one end of the first pipe wall 115. The outer peripheral wall of the first tubular connector 113 is provided with threads, and is adapted to the first threaded hole 101. The first pipe section 100 and the second pipe section 110 can be connected by screwing the first tubular connector 113 into the first threaded hole 101.
[0035] Furthermore, a first threaded hole 101 is also opened on the inner hole wall of the first tube wall 115 away from the first tubular connecting piece 113. When two adjacent second tube sections 110 are connected to each other, the first tubular connecting piece 113 on one of the second tube sections 110 extends into the first threaded hole 101 of the other second tube section 110.
[0036] It should be noted that the body 111 of the centrifuge tube is cylindrical in shape, so the outer diameter of the first tubular connector 113 is smaller than the outer diameter of the body 111. In addition, in this embodiment, the inner diameter of the first tube section 100, the inner diameter of the first tubular connector 113 and the inner diameter of the first tube wall are all the same.
[0037] In addition, an outer peripheral wall of one of the second pipe sections 110 is provided with an external thread, and an inner hole wall of the pipe cover 130 is provided with an internal thread matching the external thread, that is, the pipe cover 130 is threadedly connected to the second pipe section 110 .
[0038] Please refer to Figure 2 and Figure 3 As shown, the seal 150 is a sealing ring, and the seal 150 for sealing between the two second pipe sections 110 is sleeved on the first tubular connector 113. The seal 150 for sealing between the second pipe section 110 and the pipe cover 130 is fixed inside the pipe cover 130.
[0039] Preferably, the first pipe section 100 includes a second pipe wall 103 and a pipe tail piece 105, and a second tubular connector 107 is provided at one end of the pipe tail piece 105 close to the second pipe wall 103, and a sealing member 150 is also sleeved on the second tubular connector 107. A second threaded hole 109 for installing the second tubular connector 107 is provided on the inner hole wall of the second pipe wall 103 close to the pipe tail piece 105. When the condensate is only located in the pipe tail piece 105, the staff can directly separate the second pipe wall 103 from the pipe tail piece 105 to facilitate the acquisition of the condensate.
[0040] It should be noted that for all parts of the device that are threaded, the tightening direction of the threads is opposite to the rotation direction of the centrifuge to avoid loose connections during centrifugation that may cause liquid leakage.
[0041] Preferably, the first tube segment 100 and the plurality of second tube segments 110 are made of transparent or translucent materials, so that the staff can observe the position of the agglutinate in the centrifuge tube easily.
[0042] Preferably, the outer wall of the centrifuge tube is provided with scale lines, which is convenient for the staff to observe the volume of the body fluid specimen.
[0043] In another embodiment, the second tube segment 110 threadedly connected to the tube cover 130 may also have one end connected to the tube cover 130 changed from an external thread to a first threaded hole 101 on the inner hole wall. In this case, the tube cover 130 should be provided with a first tubular connector 113, and a seal 150 for sealing between the second tube segment 110 and the tube cover 130 is sleeved on the first tubular connector 113 connected to the tube cover 130. With the above design, when assembling the centrifuge tube, it is no longer necessary to determine the installation order of the plurality of second tube segments 110.
[0044] The utility model also provides a centrifuge tube kit, including the above-mentioned centrifuge tube, and also includes a disposable extraction spoon 200, and the disposable extraction spoon 200 is used to pick up the cell agglutinate in the centrifuge tube. The disposable extraction spoon 200 includes a spoon head 201 and a spoon handle 203, and the spoon head 201 and the spoon handle 203 are fixedly connected. The end of the spoon head 201 away from the spoon handle 203 is in contact with the inner wall of the closed section of the first tube section 100, and the end of the spoon head 201 close to the spoon handle 203 is embedded with the cylindrical body of the centrifuge tube, and the edge of the spoon head 201 is thinner, forming a thickness difference with other parts of the spoon head 201, so that the staff can collect the agglutinate at the bottom of the centrifuge tube.
[0045] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. For those skilled in the art, the present invention may be subject to various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.
Claims
1. A centrifuge tube for making cell wax blocks, characterized in that: It comprises a first pipe section, a plurality of second pipe sections and a pipe cover, wherein the plurality of second pipe sections are detachably connected in sequence to form a pipe body, and the first pipe section and the pipe cover are detachably installed at both ends of the pipe body; One end of the first pipe section connected to the pipe body is open, and the other end is closed, and both ends of the second pipe section are open; A sealing member is disposed between the first pipe segment and the second pipe segment, between two adjacent second pipe segments, and between the pipe cover and the second pipe segment.
2. A centrifuge tube for making cell wax blocks according to claim 1, characterized in that: The first pipe section is provided with a first threaded hole on the inner hole wall of the open end; The second pipe section includes a first pipe wall and a first tubular connecting member arranged at one end of the first pipe wall, and the first tubular connecting member is adapted to the first threaded hole.
3. A centrifuge tube for making cell wax blocks according to claim 2, characterized in that: A first threaded hole is also formed on the inner hole wall of the first tube wall at one end away from the first tubular connecting piece, and two adjacent second tube sections are connected through the first tubular connecting piece and the first threaded hole.
4. A centrifuge tube for making cell wax blocks according to claim 3, characterized in that: The sealing member is a sealing ring, and the sealing member is sleeved on the first tubular connecting member.
5. A centrifuge tube for making cell wax blocks according to claim 1, characterized in that: An external thread is provided on the outer peripheral wall of one of the second pipe sections, and an internal thread matching the external thread is provided on the inner hole wall of the pipe cover; The sealing member is installed inside the tube cover.
6. A centrifuge tube for making cell wax blocks according to claim 1, characterized in that: The first pipe section includes a second pipe wall and a pipe tail piece, and a second tubular connecting piece is provided at one end of the pipe tail piece close to the second pipe wall, and the sealing piece is also sleeved on the second tubular connecting piece. A second threaded hole for installing the second tubular connecting piece is opened on the inner hole wall of the second pipe wall at one end close to the pipe tail piece.
7. A centrifuge tube kit, characterized in that: include: A centrifuge tube as claimed in any one of claims 1 to 6; A disposable extraction spoon is used to pick up the cell aggregates in the centrifuge tube, comprising a spoon head and a spoon handle, wherein the spoon head and the spoon handle are fixedly connected, and one end of the spoon head away from the spoon handle is in contact with the inner wall of the closed section of the first tube section.