Shake-up equipment for cell culture

By designing a cell culture shake device that includes supporting frame, rotating rod, driving component and other components, the problem that existing equipment cannot achieve synchronous rotation of multiple culture test tubes is solved, and the synchronous shake treatment of multiple test tubes is realized, which improves the efficiency of cell culture.

CN222846700UActive Publication Date: 2025-05-09SHANXI DINGKUN HEALTH IND CO LTD
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Patent Information

Application Number
CN202421582028.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-07-05
Publication Date
2025-05-09
Estimated Expiration
2034-07-05

AI Technical Summary

Technical Problem

The existing cell culture shaker equipment cannot achieve the synchronous rotation of multiple culture test tubes, which affects the smoothing treatment of cells.

Method used

A cell culture shaker device is designed. Through supporting frames, rotating rods, driving components, connecting frames, cams and connecting springs, the synchronous rotation and reciprocating swing of the culture test tubes are realized, ensuring the synchronous shaker of multiple test tubes.

Benefits of technology

The synchronous shaking and even treatment of multiple culture test tubes is realized, which facilitates the shaking and even treatment of cells and improves the efficiency of cell culture.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the field of cell culture, in particular to cell culture shaking-up equipment which comprises a supporting bottom plate and a rolling assembly at the bottom of the supporting bottom plate. A supporting frame is arranged at the top of the supporting bottom plate, a rotating rod is rotationally mounted on the supporting frame, and a driving assembly used for driving the rotating rod to rotate is mounted in the supporting frame; a connecting frame is fixedly arranged at the end of the rotating rod, a first connecting notch is formed in one end of the connecting frame, a second motor is fixedly installed on the outer wall, located on one side of the first connecting notch, of the connecting frame, a rotating shaft is arranged on an output shaft of the second motor, and a cam is installed on the rotating shaft; one end of the connecting frame is connected with a cam, the other end of the connecting frame is connected with a placing groove through a connecting spring, the bottom of the placing groove is in contact connection with the surface of the cam, a plurality of second connecting notches are formed in the bottom of the placing groove at equal intervals, and placing cylinders are arranged at the bottoms of the second connecting notches. Therefore, the culture equipment can be conveniently used.
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Description

Technical Field

[0001] The utility model relates to the field of cell culture, in particular to a cell culture shaking device. Background Art

[0002] Cell culture is a technique for growing and propagating cells in an artificial environment, usually in a culture dish or flask. This technique provides a well-controlled environment, including appropriate temperature, pH, nutrients and humidity, to promote cell growth, division and maintenance. Cell culture has a wide range of applications in biological research, biomedical fields and biopharmaceuticals, such as disease model research, drug screening, bioengineering, etc.

[0003] Cell culture technology can transform a single cell into a simple single cell or minimally differentiated multi-cells through large-scale culture. This is an indispensable part of cloning technology, and cell culture itself is a cell clone.

[0004] During the cell culture process, a shaking device is needed to shake the cells and the nutrient solution. However, the current shaking device cannot achieve synchronous rotation of multiple culture tubes during use, which affects the use of the shaking device. Utility Model Content

[0005] The purpose of the utility model is to provide a cell culture shaking device to solve the problems raised in the above background technology.

[0006] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0007] A cell culture shaking device comprises a supporting base plate, wherein the four bottom corners of the supporting base plate are provided with rolling components for facilitating the movement of the device; a supporting frame is fixedly provided at the top center of the supporting base plate, a rotating rod is rotatably installed on the supporting frame, and a driving component for driving the rotating rod to rotate is installed inside the supporting frame; a connecting frame is fixedly provided at the end of the rotating rod located outside the top of the supporting frame, a first connecting recess is provided at one end of the connecting frame, a second motor is fixedly installed on the outer wall of the connecting frame located on one side of the first connecting recess, a rotating shaft is provided on the output shaft of the second motor, and a cam is installed on the rotating shaft; the other end of the connecting frame is connected to a placement groove through a connecting spring, and the bottom of the placement groove is contact-connected with the cam surface, a plurality of second connecting recesses are provided at equal intervals at the bottom of the placement groove, and a placement cylinder is provided at the bottom of the second connecting recess.

[0008] Preferably, the rolling assembly includes a supporting leg fixedly connected to the bottom of the supporting base plate, a roller is provided at the bottom of the supporting leg, and a brake is provided at the outer end of the roller, which can facilitate the control of the movement of the device.

[0009] Preferably, the bottom of the rotating rod is connected to the support frame via a bearing seat to ensure smooth rotation of the rotating rod.

[0010] Preferably, the driving assembly includes a first motor fixedly connected to the supporting frame, a driving gear is provided on the output shaft of the first motor, a driven gear is meshedly connected to the driving gear, and the driven gear is connected to the rotating rod for driving the rotating rod to rotate.

[0011] Preferably, an observation groove is provided at the center of the placement groove to facilitate observation and processing of the cultured cells.

[0012] Compared with the prior art, the beneficial effects of the utility model are as follows: the utility model inserts and places the culture test tubes into each second connecting recess and the inside of the placement cylinder in sequence, drives the rotating rod to rotate through the driving component, and the rotating rod drives the connecting frame to rotate. The connecting frame drives the placement slot to rotate through the cam and the connecting spring, and the placement slot can realize the synchronous rotation and shaking of the culture test tube, and then can realize the synchronous shaking of multiple culture test tubes, so as to facilitate the shaking of cells; the utility model drives the cam to rotate through the second motor drive, and the cam drives the placement slot to move, and can drive the placement slot to swing back and forth through the connecting spring, so as to realize the rapid shaking of the culture test tube, and then can facilitate the shaking of cell culture. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 The utility model is a schematic diagram of the overall structure of a cell culture shaking device.

[0014] Figure 2 This is a front view of a cell culture shaking device of the utility model.

[0015] Figure 3 This is a front sectional view of a cell culture shaking device of the utility model.

[0016] Figure 4 The utility model is a top view of a cell culture shaking device.

[0017] 1. Support base plate; 2. Support legs; 3. Rollers; 4. Brakes; 5. Support frame; 6. Rotating rod; 7. Bearing seat; 8. First motor; 9. Driving gear; 10. Driven gear; 11. Connecting frame; 12. First connecting recess; 13. Second motor; 14. Rotating shaft; 15. Cam; 16. Connecting spring; 17. Placement slot; 18. Second connecting recess; 19. Placement tube; 20. Observation slot. DETAILED DESCRIPTION

[0018] It should be noted that, in the absence of conflict, the embodiments of the present invention and the features in the embodiments can be combined with each other.

[0019] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate directions or positional relationships based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation on the present invention. In addition, the terms "first", "second", etc. are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first", "second", etc. may explicitly or implicitly include one or more of the features. In the description of the present invention, unless otherwise specified, "multiple" means two or more.

[0020] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, or it can be the internal connection of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood by specific circumstances.

[0021] The present invention will be described in detail below with reference to the accompanying drawings and in combination with embodiments.

[0022] See also Figure 1-4In an embodiment of the utility model, a cell culture shaking device comprises a supporting base plate 1, and the bottom four corners of the supporting base plate 1 are provided with rolling components for facilitating the movement of the device; a supporting frame 5 is fixedly provided at the top center of the supporting base plate 1, and a rotating rod 6 is rotatably installed on the supporting frame 5, and a driving component for driving the rotating rod 6 to rotate is installed inside the supporting frame 5; a connecting frame 11 is fixedly provided at the end of the rotating rod 6 located outside the top of the supporting frame 5, and a first connecting recess 12 is opened at one end of the connecting frame 11, and a second motor 13 is fixedly installed on the outer wall of the connecting frame 11 located on one side of the first connecting recess 12, and a rotating shaft 14 is arranged on the output shaft of the second motor 13, and a cam 15 is installed on the rotating shaft 14; the other end of the connecting frame 11 is connected to a placement groove 17 through a connecting spring 16, and the bottom of the placement groove 17 is in contact with the surface of the cam 15, and a plurality of second connecting recesses 18 are opened at equal intervals at the bottom of the placement groove 17, and a placement cylinder 19 is arranged at the bottom of the second connecting recess 18.

[0023] The utility model places the cell culture tubes in each second connection recess 18 and the placement cylinder 19 in sequence, and drives the rotating rod 6 to rotate through the driving component, and the rotating rod 6 drives the connection frame 11 to rotate and adjust the orientation. During the rotation of the connection frame 11, the second motor 13 drives the rotating shaft 14 to rotate, and the rotating shaft 14 drives the cam 15 to rotate. The cam 15 pushes the placement slot 17 and the connecting spring 16 to drive the rotating placement slot 17 and the placed culture tube to swing back and forth during the rotation, thereby facilitating the shaking of the cells.

[0024] See also Figure 1 In one embodiment of the utility model, the rolling assembly includes a support leg 2 fixedly connected to the bottom of the support base plate 1, a roller 3 is arranged at the bottom of the support leg 2, and a brake 4 is arranged at the outer end of the roller 3. The setting of the roller 3 can facilitate the adjustment of the moving direction of the equipment, and the setting of the brake 4 can realize the braking of the roller 3, thereby ensuring the safe movement of the equipment.

[0025] See also Figure 2 In one embodiment of the utility model, the bottom of the rotating rod 6 is connected to the supporting frame 5 through a bearing seat 7. The setting of the bearing seat 7 can realize the limiting processing of the rotating rod 6, thereby ensuring the smooth movement of the rotating rod 6.

[0026] See also Figure 2In one embodiment of the utility model, the driving assembly includes a first motor 8 fixedly connected to the supporting frame 5, a driving gear 9 is arranged on the output shaft of the first motor 8, a driven gear 10 is meshedly connected to the driving gear 9, and the driven gear 10 is connected to the rotating rod 6. When the first motor 8 works, the first motor 8 drives the driving gear 9 to drive the meshed driven gear 10 to rotate, and the driven gear 10 can drive the rotating rod 6 to adjust the rotational position, thereby facilitating the rotational synchronous shaking of the culture tube placed on the placement slot 17.

[0027] See also Figure 1 In one embodiment of the utility model, an observation groove 20 is provided at the center of the placement groove 17. The setting of the observation groove 20 can facilitate the observation and processing of the cultured and shaken cells, thereby facilitating the use of the device.

[0028] Working principle: The utility model places the culture test tubes into the second connecting recess 18 and the placement cylinder 19, so that the culture test tubes can be stored and processed in sequence. The first motor 8 works, the first motor 8 drives the driving gear 9 to rotate, and the driving gear 9 drives the meshing driven gear 10 to rotate. The driven gear 10 can drive the rotating rod 6 to rotate, and the rotating rod 6 can drive the connecting frame 11 to rotate. The connecting frame 11 drives the placement slot 17 to rotate synchronously through the cam 15 and the connecting spring 16, and the placement slot 17 drives the placed culture test tubes to rotate synchronously and shake them evenly. During the rotation of the placement slot 17, the second motor 13 works, and the second motor 13 drives the rotating shaft 14 to drive the cam 15 to rotate. The cam 15 can push the placement slot 17 to swing back and forth in cooperation with the connecting spring 16, so that the culture test tubes can be quickly shaken evenly, which facilitates the culture and processing of cells.

[0029] It is obvious to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above, and that the present invention can be implemented in other specific forms without departing from the spirit or essential features of the present invention. Therefore, the embodiments should be regarded as exemplary and non-restrictive from any point of view, and the scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims be included in the present invention. Any reference numeral in a claim should not be regarded as limiting the claim to which it relates.

Claims

1. A cell culture shaking device, comprising a supporting bottom plate, characterized in that: The four corners of the bottom of the supporting base plate are provided with rolling components to facilitate the movement of the equipment; A support frame is fixedly provided at the top center of the support bottom plate, a rotating rod is rotatably mounted on the support frame, and a driving component for driving the rotating rod to rotate is installed inside the support frame; A connecting frame is fixedly arranged at the end of the rotating rod located outside the top of the supporting frame, a first connecting notch is opened at one end of the connecting frame, a second motor is fixedly installed on the outer wall of the connecting frame located on one side of the first connecting notch, a rotating shaft is arranged on the output shaft of the second motor, and a cam is installed on the rotating shaft; The other end of the connection frame is connected to the placement groove through a connection spring, and the bottom of the placement groove is in contact with the cam surface. A plurality of second connection recesses are evenly spaced at the bottom of the placement groove, and a placement tube is provided at the bottom of the second connection recess.

2. A cell culture shaking device according to claim 1, characterized in that: The rolling assembly comprises a support leg fixedly connected to the bottom of the support base plate, a roller is arranged at the bottom of the support leg, and a brake is arranged at the outer end of the roller.

3. A cell culture shaking device according to claim 1, characterized in that: The bottom of the rotating rod is connected to the supporting frame through a bearing seat.

4. A cell culture shaking device according to claim 1, characterized in that: The driving assembly comprises a first motor fixedly connected to the supporting frame, a driving gear is arranged on the output shaft of the first motor, a driven gear is meshedly connected to the driving gear, and the driven gear is connected to the rotating rod.

5. The cell culture shaking device according to claim 1, characterized in that: An observation slot is arranged at the center of the placement slot.