Rapid extraction and separation detection tube for urine sample

By designing a rapid extraction and separation detection tube for urine sample, using liquid-liquid extraction method and filter element technology, the problems of cumbersome traditional urine detection technology and require laboratory conditions are solved, and the effects of portability, real-time detection and convenient operation are achieved.

CN222850616UActive Publication Date: 2025-05-09ZHEJIANG BIOREAR BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202421190718.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-28
Publication Date
2025-05-09
Estimated Expiration
2034-05-28

AI Technical Summary

Technical Problem

Traditional urine detection technology is cumbersome and requires the use of corresponding instruments in a fixed laboratory. The lack of convenient devices for collection and testing, resulting in wasting time and energy of the personnel to be tested during testing.

Method used

A urine sample rapid extraction and separation detection tube is designed, including a first detection tube and a second detection tube. The liquid-liquid extraction method and filter element technology are used to achieve rapid extraction-separation-purification-detection through shaking and dropping operations.

Benefits of technology

It realizes portable testing, can be tested in real time on site, and results are obtained through visual windows. It is convenient and fast to operate, and can be tested at home without laboratory, making it safer.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of urine detection, in particular to a urine sample rapid extraction and separation detection tube which comprises a first detection tube and a second detection tube, the first detection tube and the second detection tube respectively comprise a storage tube and a mixing tube, a storage cavity is formed in the storage tube, and a sealing aluminum film is arranged at the tail end of the storage tube; a mixing cavity is formed in the mixing pipe, through holes are formed in the two ends of the mixing pipe, an assembly end is arranged on the side, close to the storage pipe, of the mixing pipe, first hydrophilic filter elements are arranged in the through holes in the two sides of the mixing pipe in the first detection pipe, and a hydrophobic filter element is arranged in the through hole in the side, close to the storage pipe, of the mixing pipe in the second detection pipe. A second hydrophilic filter element is arranged in a through hole in one side, far away from the storage pipe, of the mixing pipe in the second detection pipe. The device is portable and efficient, a result can be obtained through a visual window in a field real-time test, rapid extraction-separation-purification-detection is realized, and the device is more convenient and faster to operate, can be separated from a laboratory for household detection, and is safer.
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Description

Technical Field

[0001] The utility model relates to the technical field of urine detection, in particular to a urine sample rapid extraction and separation detection tube. Background Art

[0002] Urine test is one of the most direct methods to detect whether there are banned drugs in the human body. When it is necessary to detect whether there are drugs in urine, the urine sample must first be pre-treated to remove endogenous interfering substances in the urine sample. Most drugs are lipophilic, and most endogenous interfering substances in urine are highly polar water-soluble substances. Organic solvent extraction can remove most of the interfering substances. This method of extracting substances from the aqueous phase from the organic phase is liquid-liquid extraction, which is a common method for purifying biological samples.

[0003] The testing of traditional technical solutions is cumbersome and requires the use of corresponding instruments in a fixed laboratory. The detection lacks convenient devices for collection and detection. During the detection, professional personnel are still required to hold a sample gun for testing, which still wastes the time and energy of the personnel to be tested. Utility Model Content

[0004] The utility model solves the problems of the prior art and provides a urine sample rapid extraction and separation detection tube.

[0005] The purpose of the utility model can be achieved through the following technical solutions: a urine sample rapid extraction and separation test tube, comprising: a first test tube and a second test tube, the first test tube and the second test tube both comprising a storage tube and a mixing tube, the storage tube is provided with a storage cavity inside and a sealing aluminum film is provided at the end, the mixing tube is provided with a mixing cavity inside and through holes are provided at both ends, an assembly end is provided on the side of the mixing tube close to the storage tube, a first hydrophilic filter element is provided in the through holes on both sides of the mixing tube in the first test tube, a hydrophobic filter element is provided in the through hole on the side of the mixing tube close to the storage tube in the second test tube, and a second hydrophilic filter element is provided in the through hole on the side of the mixing tube in the second test tube away from the storage tube.

[0006] As a further improvement, a mating end is provided on one side of the storage tube close to the mixing tube, a first convex ring is provided inside the mating end, a second convex ring is provided outside the assembly end of the mixing tube, and the first convex ring and the second convex ring are provided correspondingly.

[0007] As a further improvement, there are multiple groups of the first convex rings.

[0008] As a further improvement, waste liquid tanks are provided on both sides of the assembly end of the mixing tube.

[0009] As a further improvement, the inner diameter of the mixing chamber on the side close to the storage tube is a, and the inner diameter of the mixing chamber on the side away from the storage tube is b, satisfying the quantitative relationship: a>b.

[0010] Compared with the prior art, the utility model has the following beneficial effects: compared with the traditional technical solution, the test is cumbersome and requires the use of corresponding instruments in a fixed laboratory, the utility model is portable and efficient, and can be tested in real time on site to obtain results through a visual window, thereby realizing rapid extraction-separation-purification-detection, making the operation more convenient and faster, and can be tested at home without being in the laboratory, which is safer. BRIEF DESCRIPTION OF THE DRAWINGS

[0011] Figure 1 It is a structural schematic diagram of the utility model;

[0012] Figure 2 It is a cross-sectional view of the first detection tube of the utility model;

[0013] Figure 3 It is a cross-sectional view of the second detection tube of the utility model;

[0014] Figure 4 For this utility model Figure 3 Enlarged view of part A in the figure.

[0015] In the figure, 1, first detection tube; 2, second detection tube; 31, storage tube; 311, storage chamber; 312, sealing aluminum film; 313, matching end; 3131, first convex ring; 32, mixing tube; 321, mixing chamber; 3211, through hole; 322, assembly end; 3221, second convex ring; 323, waste liquid tank; 41, first hydrophilic filter element; 51, hydrophobic filter element; 52, second hydrophilic filter element. DETAILED DESCRIPTION

[0016] In the description of the present invention, it should be noted that the terms "center", "up", "down", "left", "right", "vertical", "horizontal", "inside", "outside", etc. indicate directions or positional relationships based on the directions or positional relationships shown in the accompanying drawings. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction. Therefore, they cannot be understood as limitations on the present invention.

[0017] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0018] Below is a combination of the embodiments and the attached Figures 1 to 4 , the technical solution of the utility model is further elaborated.

[0019] Example 1

[0020] A urine sample rapid extraction and separation test tube, comprising: a first test tube 1 and a second test tube 2, wherein the first test tube 1 and the second test tube 2 both comprise a storage tube 31 and a mixing tube 32, wherein the storage tube 31 is provided with a storage cavity 311 inside and a sealing aluminum film 312 at the end, wherein the mixing tube 32 is provided with a mixing cavity 321 inside and through holes 3211 at both ends, wherein an assembly end 322 is provided at one side of the mixing tube 32 close to the storage tube 31, and waste liquid tanks 323 are provided at both sides of the assembly end 322 of the mixing tube 32, wherein first hydrophilic filter elements 41 are provided in the through holes 3211 at both sides of the mixing tube 32 in the first test tube 1, wherein a hydrophobic filter element 51 is provided in the through hole 3211 at one side of the mixing tube 32 close to the storage tube 31 in the second test tube 2, and wherein a second hydrophilic filter element 52 is provided in the through hole 3211 at the side of the mixing tube 32 away from the storage tube 31 in the second test tube 2.

[0021] like Figures 1 to 4 As shown, during the use of the utility model, firstly, a dichloromethane reagent is injected into the storage tube 31 of the first detection tube 1, anhydrous sodium sulfate in a freeze-dried powder state is injected into the mixing tube 32 of the first detection tube 1, and an aqueous phase reagent is injected into the storage tube 31 of the second detection tube 2. The specific use steps are as follows:

[0022] S1: Open the sealed aluminum film 312 of the storage tube 31 in the first detection tube 1, add the urine sample and insert it into the mixing tube 32 of the first detection tube 1, hold the outer wall of the mixing tube 32 of the first detection tube 1, and shake it left and right to mix it, with an arc of about 90°, for more than 10 cycles;

[0023] S2: Invert the first detection tube 1 for more than 10 seconds to allow the liquid in the storage tube 31 to be fully mixed and liquefied with the dry powder anhydrous sodium sulfate in the mixing tube 32, then open the sealing aluminum film 312 of the storage tube 31 in the second detection tube 2, press the end of the storage tube 31 in the first detection tube 1, so that the mixed and liquefied reagent in the first detection tube 1 is dripped into the storage cavity 311 of the storage tube 31 in the second detection tube 2 for mixing (3 to 4 drops are sufficient);

[0024] S3: insert the storage tube 31 in the second detection tube 2 into the mixing tube 32 of the second detection tube 2, grasp the outer wall of the mixing tube 32 of the second detection tube 2, and shake it left and right to mix it, with an arc of about 90°, for more than 10 cycles;

[0025] S4: After shaking, the liquid in the storage tube 31 of the second detection tube 2 is in a stratified state due to the action of the aqueous phase reagent. The target detection sample is in the upper layer due to its light density. The storage tube assembly is inverted to allow the non-target sample to precipitate in the waste liquid tank 323. During the precipitation process, the hydrophobic filter element can prevent the non-target reagent from flowing through the filter element. The precipitation time is more than 10 seconds. Then, the outer wall of the storage tube 31 in the second detection tube 2 is gently pinched to allow the target sample to pass through the filter element and drip into the tube to be detected. 3-4 drops are enough. Optical detection or antigen detection is performed to achieve the purpose of detection.

[0026] Compared with the traditional technical solution, the test is complicated and needs to use corresponding instruments in a fixed laboratory. The advantage of the present invention lies in portability and efficiency, and the results can be obtained through a visual window in real time on site.

[0027] As a further preferred embodiment, a mating end 313 is provided on the side of the storage tube 31 close to the mixing tube 32, a first convex ring 3131 is provided inside the mating end 313, a second convex ring 3221 is provided outside the assembly end 322 of the mixing tube 32, and the first convex ring 3131 and the second convex ring 3221 are provided correspondingly.

[0028] As a further preferred embodiment, the first convex rings 3131 are provided in multiple groups.

[0029] Specifically, when the storage tube 31 and the mixing tube 32 are being assembled, the first convex ring 3131 and the second convex ring 3221 can form a double sealing structure to improve the sealing performance of the equipment. At the same time, the first convex ring 3131 can play a role in straightening during assembly to prevent the test tube from tilting and affecting the sealing during the assembly process.

[0030] As a further preferred embodiment, the inner diameter of the mixing chamber 321 close to the storage tube 31 is a, and the inner diameter of the mixing chamber 321 away from the storage tube 31 is b, satisfying the quantitative relationship: a>b.

[0031] The preferred specific embodiments of the utility model are described in detail above. It should be understood that ordinary technicians in this field can make many modifications and changes based on the concept of the utility model without creative work. Therefore, all technical solutions that can be obtained by technicians in this technical field based on the concept of the utility model through logical analysis, reasoning or limited experiments on the basis of the existing technology should be within the scope of protection determined by the claims.

Claims

1. A urine sample rapid extraction and separation test tube, characterized in that: include: The first detection tube (1) and the second detection tube (2) each comprise a storage tube (31) and a mixing tube (32); the storage tube (31) is provided with a storage cavity (311) inside and a sealing aluminum film (312) is provided at the end; the mixing tube (32) is provided with a mixing cavity (321) inside and through holes (3211) are provided at both ends; and the mixing tube (32) is provided with an assembly on one side close to the storage tube (31). The first detection tube (1) has a through hole (3211) on both sides of the mixing tube (32) provided with a first hydrophilic filter core (41), the second detection tube (2) has a through hole (3211) on one side of the mixing tube (32) close to the storage tube (31) provided with a hydrophobic filter core (51), and the second detection tube (2) has a through hole (3211) on one side of the mixing tube (32) away from the storage tube (31) provided with a second hydrophilic filter core (52).

2. A urine sample rapid extraction and separation test tube according to claim 1, characterized in that: A mating end (313) is provided on one side of the storage tube (31) close to the mixing tube (32), a first convex ring (3131) is provided inside the mating end (313), a second convex ring (3221) is provided outside the assembly end (322) of the mixing tube (32), and the first convex ring (3131) and the second convex ring (3221) are provided correspondingly.

3. A urine sample rapid extraction and separation test tube according to claim 2, characterized in that: The first convex rings (3131) are provided in multiple groups.

4. A urine sample rapid extraction and separation test tube according to claim 1, characterized in that: Waste liquid tanks (323) are provided on both sides of the assembly end (322) of the mixing tube (32).

5. A urine sample rapid extraction and separation test tube according to claim 1, characterized in that: The inner diameter of the mixing chamber (321) on the side close to the storage tube (31) is a, and the inner diameter of the mixing chamber (321) on the side away from the storage tube (31) is b, satisfying the quantitative relationship: a>b.