Efficient ergothioneine biosynthesis reactor

By designing an Ergothionine biosynthesis reactor with integrated stirring and temperature control system and dynamic electrical connection solutions, the problems of uneven stirring, temperature control hysteresis and electrical connection in traditional reactors are solved, and the production efficiency and product quality are significantly improved.

CN222861501UActive Publication Date: 2025-05-13谢春锋
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Patent Information

Application Number
CN202421697142.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-07-18
Publication Date
2025-05-13
Estimated Expiration
2034-07-18

AI Technical Summary

Technical Problem

Traditional ergothio is difficult to meet the high requirements of modern biopharmaceutical industry for production efficiency and product quality due to the uneven stirring, hysteresis of temperature control, and unstable electrical connections.

Method used

A highly efficient ergothionine biosynthesis reactor was designed. Through an integrated stirring and temperature control system, the same stirring shaft was used to achieve uniform stirring and precise control of raw materials, and the reliability design of dynamic electrical connection solutions and elastic connectors ensured the continuity and accuracy of temperature control.

Benefits of technology

It significantly improves the production efficiency and product quality of ergothionein, solves the problems of uneven stirring, temperature control hysteresis and unstable electrical connections, and meets the needs of the modern biopharmaceutical industry.

✦ Generated by Eureka AI based on patent content.

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Abstract

The efficient ergothioneine biosynthesis reactor comprises a reaction kettle, a plurality of supporting legs are fixedly connected to the outer side of the lower end of the reaction kettle, a discharging pipe is communicated with the center of the lower end of the reaction kettle, and feeding pipes are communicated with the left side and the right side of the upper end of the reaction kettle; a stirring motor is fixedly connected to the center of the upper end of the reaction kettle through a supporting frame, a connecting rotating shaft is rotatably connected to the center of the lower end of the stirring motor through a rotating shaft, and the connecting rotating shaft is rotatably connected to the interior of the center of the upper end of the reaction kettle. Uniform stirring of raw materials and accurate temperature control are achieved through the same stirring rotating shaft, the fermentation efficiency and the production efficiency are improved, a connecting rotating groove, a connecting electrode plate, a connecting rotating ring, a connecting electrode column and other components are designed according to the dynamic power supply requirement of a temperature control pipe in the stirring process, it is ensured that power can still be stably supplied in the rotating motion, and the production efficiency is improved. And continuity and accuracy of temperature control are guaranteed.
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Description

Technical Field

[0001] The utility model belongs to the technical field related to ergothioneine biosynthesis, and specifically relates to a high-efficiency ergothioneine biosynthesis reactor. Background Art

[0002] In the field of biopharmaceuticals, ergothioneine is an important bioactive substance, and its biosynthesis process has always been the focus of research and production. Traditional ergothioneine synthesis reactors usually use independent stirring systems and temperature control systems, which often have problems such as uneven stirring, lagging temperature control, and unstable electrical connections.

[0003] With the development of biotechnology, higher requirements are put forward for the production efficiency and product quality of ergothioneine. However, the existing technology has limitations in stirring efficiency, temperature control accuracy, electrical connection stability and operation convenience, and a new reactor design is urgently needed to overcome these problems.

[0004] The high-efficiency thioneine biosynthesis reactor of the present invention aims to solve the above-mentioned technical problems, and through technological innovation, the production efficiency and product quality of thioneine can be significantly improved, thus meeting the needs of the modern biopharmaceutical industry. Utility Model Content

[0005] The utility model aims to provide a high-efficiency thioneine biosynthesis reactor, to solve the problems of uneven stirring, delayed temperature control and unstable electrical connection in the traditional thioneine synthesis reactor proposed in the above-mentioned background technology.

[0006] To achieve the above object, the utility model provides the following technical scheme: a kind of efficient thioneine biosynthesis reactor, including a reactor, a plurality of supporting legs are fixedly connected to the outside of the lower end of the reactor, and a discharge pipe is connected to the center of the lower end of the reactor, and a feed pipe is connected to both the left and right sides of the upper end of the reactor, and a stirring motor is fixedly connected to the center of the upper end of the reactor through a support frame, and a connecting shaft is rotatably connected to the center of the lower end of the stirring motor through a rotating shaft, and the connecting shaft is rotatably connected to the inside of the center of the upper end of the reactor, and a stirring shaft is fixedly connected to the lower end of the connecting shaft, and the stirring shaft is rotatably connected to the inside of the reactor, a plurality of stirring blades are fixedly connected to the lower side of the outer wall of the stirring shaft cylinder, a plurality of connecting rods are fixedly connected to the upper side of the outer wall of the stirring shaft cylinder, and a plurality of temperature control tubes are connected to the lower ends of the plurality of connecting rods.

[0007] Preferably, the temperature control tube is connected to the interior of the connecting shaft through a wiring harness, and the wiring harness is connected to the interior of the connecting shaft through a connecting support rod and the interior of the stirring shaft, and a plurality of heat dissipation rods are fixedly connected to the cylindrical outer wall of the temperature control tube.

[0008] Preferably, a connecting groove is opened inside the outer wall of the connecting shaft cylinder, and connecting electrode sheets are sleeved on the upper and lower sides of the inner wall of one end of the connecting groove close to the central axis of the connecting shaft, and the two connecting electrode sheets are connected to multiple temperature control tubes through wiring harnesses.

[0009] Preferably, a connecting swivel is clamped inside the connecting rotating groove, and the connecting swivel is rotatably connected inside the connecting rotating groove, and connecting electrode columns are inserted inside the upper and lower sides of the left end of the connecting swivel.

[0010] Preferably, the left end of the connecting electrode column is connected to the inner wall of the support frame arranged at the center of the upper end of the reactor, and the left end of the connecting electrode column is connected to a power harness, and the power harness runs through the inside of the support frame.

[0011] Preferably, an elastic connector is provided on the right side of the connecting electrode column, a telescopic rod is fixedly connected to the center of the left end of the elastic connector, a telescopic hole is opened inside the center of the right end of the connecting electrode column, and the telescopic rod is slidably connected inside the telescopic hole.

[0012] Preferably, a compression spring is provided at the left end of the telescopic rod, and the compression spring is located inside the telescopic hole, the elastic connector is elastically connected to the right end of the connecting electrode column through the telescopic rod and the compression spring, and the right end of the elastic connector is tightly fitted on the outer wall of the connecting electrode sheet.

[0013] Compared with the prior art, the utility model provides a high-efficiency ergothioneine biosynthesis reactor, which has the following beneficial effects:

[0014] 1. Integrated stirring and temperature control system: The stirring function and temperature control function are innovatively integrated into one, and the uniform stirring of raw materials and precise temperature control are achieved through the same stirring shaft, which improves fermentation efficiency and production efficiency.

[0015] 2. Dynamic electrical connection solution: In view of the dynamic power supply requirements of the temperature control tube during the stirring process, components such as the connecting trough, connecting electrode sheet, connecting swivel and connecting electrode column are designed to ensure stable power supply during the rotation movement and guarantee the continuity and accuracy of temperature control.

[0016] 3. Reliability design of elastic connector: The elastic connector and telescopic rod mechanism are introduced to achieve close contact with the connecting electrode sheet by squeezing the spring, which can maintain the reliability of electrical connection even under long-term operation and friction, reducing the risk of failure caused by poor contact.

[0017] 4. Heat dissipation rods enhance temperature control effect: Multiple heat dissipation rods are fixedly connected to the outer wall of the temperature control tube, which increases the contact area with the raw materials, allowing the temperature control tube to control the fermentation temperature more evenly and quickly, thereby improving the efficiency and effect of temperature regulation. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 The utility model is a schematic diagram of the three-dimensional structure of an ergothioneine reactor.

[0019] Figure 2 The utility model is a schematic diagram of the three-dimensional cross-sectional structure of an ergothioneine reactor.

[0020] Figure 3 It is a schematic diagram of the stirring shaft connection structure of the utility model.

[0021] Figure 4 It is a schematic diagram of the connecting shaft connection structure of the utility model.

[0022] Figure 5 For the utility model Figure 4 Enlarged schematic diagram at point A in the middle.

[0023] In the figure: 1. Reactor; 2. Support legs; 3. Feed pipe; 4. Stirring motor; 5. Connecting shaft; 6. Stirring shaft; 7. Stirring blades; 8. Connecting support rod; 9. Temperature control tube; 10. Heat dissipation rod; 11. Connecting trough; 12. Connecting electrode sheet; 13. Connecting swivel; 14. Connecting electrode column; 15. Elastic connector; 16. Telescopic rod; 17. Telescopic hole; 18. Extrusion spring. DETAILED DESCRIPTION

[0024] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0025] The utility model provides Figure 1-Figure 5A kind of efficient ergothioneine biosynthesis reactor shown, comprises a reactor 1, a plurality of supporting legs 2 are fixedly connected to the outside of the lower end of the reactor 1, and a discharge pipe is connected to the center of the lower end of the reactor 1, and a feed pipe 3 is connected to both sides of the upper left and right sides of the reactor 1, and a stirring motor 4 is fixedly connected to the center of the upper end of the reactor 1 through a support frame, and a connecting shaft 5 is rotatably connected to the center of the lower end of the stirring motor 4 through a rotating shaft, and the connecting shaft 5 is rotatably connected to the inside of the center of the upper end of the reactor 1, and a stirring shaft 6 is fixedly connected to the lower end of the connecting shaft 5, and the stirring shaft 6 is rotatably connected to the inside of the reactor 1, and a plurality of stirring blades 7 are fixedly connected to the lower side of the outer wall of the cylinder of the stirring shaft 6, and a plurality of connecting rods 8 are fixedly connected to the upper side of the outer wall of the cylinder of the stirring shaft 6, and a plurality of temperature control tubes 9 are connected to the lower ends of the plurality of connecting rods 8, and the synthetic raw materials are passed through both sides. The feed pipe 3 is added to the inside of the reactor 1, and fermentation synthesis is carried out inside the reactor 1, the reactor 1 is supported and stood by multiple supporting legs 2 arranged at the lower end, and the synthesized thioneine is exported by the discharge port at the lower end of the reactor 1, and in the building-up process, the stirring motor 4 drives the stirring shaft 6 arranged inside the reactor 1 by the connecting shaft 5 of the rotating shaft and the lower end to rotate, the stirring shaft 6 stirs the raw material by multiple stirring blades 7 arranged outside, and temperature is controlled by multiple temperature control tubes 9 arranged outside the stirring shaft 6, multiple temperature control tubes 9 are connected with the stirring shaft 6 by multiple connecting rods 8, and are connected with the connecting shaft 5 inside by a wiring harness, so that thioneine can be fermented in a suitable environment, and can be evenly fermented, thereby improving the fermentation efficiency of thioneine, and improving production efficiency.

[0026] Preferably, the temperature control tube 9 is connected to the interior of the connecting shaft 5 through a wiring harness, and the wiring harness is connected to the interior of the connecting shaft 5 through the connecting support rod 8 and the interior of the stirring shaft 6. A plurality of heat dissipation rods 10 are fixedly connected to the cylindrical outer wall of the temperature control tube 9. In the process of the plurality of temperature control tubes 9 controlling the fermentation temperature inside the reactor 1, the temperature control tube 9 can increase the contact area with the raw materials through the plurality of heat dissipation rods 10 arranged externally, so that the temperature control tube 9 can control the fermentation temperature evenly and quickly through the plurality of heat dissipation rods 10.

[0027] Preferably, a connecting groove 11 is provided inside the cylindrical outer wall of the connecting shaft 5, and connecting electrode sheets 12 are sleeved on both upper and lower sides of the inner wall of one end of the connecting groove 11 close to the central axis of the connecting shaft 5, and the two connecting electrode sheets 12 are connected to multiple temperature control tubes 9 through a wiring harness, and a connecting ring 13 is clamped inside the connecting groove 11, and the connecting ring 13 is rotatably connected inside the connecting groove 11, and connecting electrode columns 14 are inserted inside the upper and lower sides of the left end of the connecting ring 13, and the left end of the connecting electrode column 14 is connected to the inner wall of the support frame set at the center of the upper end of the reactor 1 A power harness is connected to the left end of the connecting electrode column 14, and the power harness runs through the inside of the support frame. Multiple temperature control tubes 9 can be connected to the two connecting electrode sheets 12 inside the connecting rotating groove 11 through the harness, and can be connected to an external power source through the two connecting electrode columns 14 inside the connecting rotating ring 13. The connecting rotating ring 13 can rotate outside the connecting shaft 5 through the connecting rotating groove 11, and enable the two connecting electrode columns 14 to be rotatably connected to the outside of the two connecting electrode sheets 12, so that multiple temperature control tubes 9 can be stably connected to an external power source during the rotation process.

[0028] Preferably, an elastic connector 15 is provided on the right side of the connecting electrode column 14, a telescopic rod 16 is fixedly connected at the center of the left end of the elastic connector 15, a telescopic hole 17 is opened inside the center of the right end of the connecting electrode column 14, and the telescopic rod 16 is slidably connected inside the telescopic hole 17, an extrusion spring 18 is provided at the left end of the telescopic rod 16, and the extrusion spring 18 is located inside the telescopic hole 17, the elastic connector 15 is elastically connected to the right end of the connecting electrode column 14 through the telescopic rod 16 and the extrusion spring 18, and the right end of the elastic connector 15 is tightly fitted on the outer wall of the connecting electrode sheet 12, so that the connecting electrode column 14 can be connected to the connecting electrode sheet 12 through the elastic connector 15 at the right end, and the elastic connector 15 can be elastically connected to the right end of the connecting electrode column 14 through the telescopic rod 16 and the extrusion spring 18, so that the elastic connector 15 can always be connected to the connecting electrode sheet 12 under the action of the extrusion spring 18, preventing the elastic connector 15 from poor contact with the connecting electrode sheet 12 due to wear or bouncing, and further ensuring the connection stability of multiple temperature control tubes 9.

[0029] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. An efficient thioneine biosynthesis reactor, characterized in that, The invention comprises a reactor (1), wherein a plurality of support legs (2) are fixedly connected to the outer side of the lower end of the reactor (1), and a discharge pipe is connected to the center of the lower end of the reactor (1), and a feed pipe (3) is connected to the left and right sides of the upper end of the reactor (1), and a stirring motor (4) is fixedly connected to the center of the upper end of the reactor (1) through a support frame, and a connecting shaft (5) is rotatably connected to the center of the lower end of the stirring motor (4) through a rotating shaft, and the connecting shaft (5) is rotatably connected to the inside of the center of the upper end of the reactor (1), and a stirring shaft (6) is fixedly connected to the lower end of the connecting shaft (5), and the stirring shaft (6) is rotatably connected to the inside of the reactor (1), and a plurality of stirring blades (7) are fixedly connected to the lower side of the cylindrical outer wall of the stirring shaft (6), and a plurality of connecting rods (8) are fixedly connected to the upper side of the cylindrical outer wall of the stirring shaft (6), and a plurality of temperature control tubes (9) are connected to the lower ends of the plurality of connecting rods (8).

2. a kind of efficient thioneine biosynthesis reactor according to claim 1, is characterized in that: The temperature control tube (9) is connected to the interior of the connecting shaft (5) via a wiring harness, and the wiring harness is connected to the interior of the connecting shaft (5) via a connecting support rod (8) and the interior of the stirring shaft (6). A plurality of heat dissipation rods (10) are fixedly connected to the cylindrical outer wall of the temperature control tube (9).

3. a kind of efficient thioneine biosynthesis reactor according to claim 1, is characterized in that: A connecting groove (11) is provided inside the cylindrical outer wall of the connecting rotating shaft (5), and connecting electrode sheets (12) are sleeved on both upper and lower sides of the inner wall of one end of the connecting rotating shaft (11) close to the central axis of the connecting rotating shaft (5), and the two connecting electrode sheets (12) are connected to the plurality of temperature control tubes (9) via a wiring harness.

4. a kind of efficient thioneine biosynthesis reactor according to claim 3, is characterized in that: A connecting rotating ring (13) is clamped inside the connecting rotating groove (11), and the connecting rotating ring (13) is rotatably connected inside the connecting rotating groove (11), and connecting electrode columns (14) are inserted inside the upper and lower sides of the left end of the connecting rotating ring (13).

5. a kind of efficient thioneine biosynthesis reactor according to claim 4, is characterized in that: The left end of the connecting electrode column (14) is connected to the inner wall of a support frame arranged at the center of the upper end of the reactor (1), and the left end of the connecting electrode column (14) is connected to a power harness, which runs through the interior of the support frame.

6. a kind of efficient thioneine biosynthesis reactor according to claim 5, is characterized in that: An elastic connector (15) is arranged on the right side of the connecting electrode column (14); a telescopic rod (16) is fixedly connected to the center of the left end of the elastic connector (15); a telescopic hole (17) is opened inside the center of the right end of the connecting electrode column (14), and the telescopic rod (16) is slidably connected inside the telescopic hole (17).

7. A highly efficient thioneine biosynthesis reactor according to claim 6, characterized in that: The left end of the telescopic rod (16) is provided with a squeezing spring (18), and the squeezing spring (18) is located inside the telescopic hole (17); the elastic connector (15) is elastically connected to the right end of the connecting electrode column (14) through the telescopic rod (16) and the squeezing spring (18), and the right end of the elastic connector (15) is tightly fitted on the outer wall of the connecting electrode sheet (12).