Position movement device for biological sample imaging

Abstract

The utility model relates to a position movement device, in particular to a position movement device for biological sample imaging. The utility model discloses a position movement device for biological sample imaging. The position movement device comprises an equipment box body, a guide supporting assembly arranged in the equipment box body and a sample placement adjusting assembly arranged on the guide supporting assembly. The utility model aims to provide the position movement device for biological sample imaging, which is simple in structure, convenient to adjust and more stable.

Description

Technical Field

[0001] The utility model relates to a position movement device, in particular to a position movement device for biological sample imaging. Background Art

[0002] Biological optical imaging refers to a method of obtaining biological information by using optical detection means in combination with optical detection molecules to image cells, tissues or even organisms. If biological optical imaging is limited to the range of visible light and near-infrared light, according to different detection methods, biological optical imaging can be divided into fluorescence imaging, bioluminescence imaging, photoacoustic imaging, optical tomography imaging, etc.

[0003] At present, the cameras used for biological sample gel imaging are generally large-aperture fixed-focus lenses. Such lenses can generally only perform fixed-focus imaging and need to adjust the object distance by placing partitions at different positions. Therefore, different partitions need to be replaced when photographing different samples, which is extremely inconvenient to use and the whole process is not stable enough, easily causing the position of the biological sample to slip. Content of the Utility Model

[0004] In view of this, the utility model provides a position movement device for biological sample imaging. The purpose is to provide a position movement device for biological sample imaging with a simple structure, convenient adjustment and more stability.

[0005] To achieve the above object, the utility model adopts the following technical solutions:

[0006] A position movement device for imaging biological samples, comprising an equipment box body, a guiding and supporting component arranged in the equipment box body, and a sample placement and adjustment component arranged on the guiding and supporting component; the guiding and supporting component includes a bottom support plate horizontally arranged in the middle of the equipment box body, guiding rods are correspondingly and vertically arranged upward at four ends of the bottom support plate, a top support plate is horizontally spanned above the four guiding rods correspondingly, a camera tray is spanned above the top support plate through four vertically arranged support rods, a lens fixing hole is vertically penetrated through the camera tray, and a perspective through hole is vertically penetrated through the top support plate corresponding to the lens fixing hole; the sample placement and adjustment component includes a fixed cylinder body, the middle periphery of the fixed cylinder body is fixedly embedded in the middle of the bottom support plate, a first sliding groove is formed on the inner wall of the fixed cylinder body, a first adjusting cylinder body is slidably arranged in the first sliding groove through a first sliding block correspondingly, a second sliding groove is formed on the inner wall of the first adjusting cylinder body, a second adjusting cylinder body is slidably arranged in the second sliding groove through a second sliding block correspondingly, the fixed end of an electric lifting rod is fixedly connected to the bottom inner wall of the fixed cylinder body, the moving end of the electric lifting rod is fixedly arranged on the top inner wall of the second adjusting cylinder body, a buffer connecting plate, a sample placement table and a biological sample are correspondingly arranged above the second adjusting cylinder body from bottom to top in sequence, wherein four ends of the sample placement table are slidably sleeved on the peripheries of the four guiding rods.

[0007] Preferably, a control console is arranged at the bottom inside the equipment box body, a controller is arranged inside the control console, a keyboard is arranged outside the equipment box body corresponding to the control console, and the keyboard is electrically connected to the controller.

[0008] Preferably, a wire guiding hole is formed at the bottom of the fixed cylinder body corresponding to the electric lifting rod, and the electric lifting rod is electrically connected to the controller through a wire in the wire guiding hole.

[0009] Preferably, an observation window is arranged on the front side of the equipment box body, and a grasping handle is correspondingly arranged on the observation window.

[0010] Preferably, a rubber ring plate is arranged above the fixed cylinder body corresponding to the outer edge of its top.

[0011] Preferably, both the buffer connecting plate and the sample placement table are horizontally arranged.

[0012] Preferably, the length of the first sliding groove is greater than the length of the second sliding groove.

[0013] The beneficial effects of the present utility model are as follows:

[0014] 1. The utility model includes an equipment box body, a guiding and supporting component arranged in the equipment box body, and a sample placing and adjusting component arranged on the guiding and supporting component. This setting provides a space for placing and installing the guiding and supporting component through the equipment box body, and provides a space for the movement and adjustment of the sample placing and adjusting component. The setting of the guiding and supporting component lays a foundation for the installation of the sample placing and adjusting component and the guiding during movement. The sample placing and adjusting component is used to place the biological sample and adjust the height of the biological sample. Generally speaking, compared with the previous position movement device for biological sample imaging, this position movement device for biological sample imaging can adjust the sample placing and adjusting component through a simple principle to meet the needs of different object distances during fixed-focus imaging, with a simple structure, easy to adjust, and more stable. The guiding and supporting component includes a bottom support plate horizontally arranged in the middle of the equipment box body. Four end parts of the bottom support plate are correspondingly and vertically provided with guiding rods. Above the four guiding rods, a top support plate is horizontally spanned correspondingly. Above the top support plate, a camera tray is spanned through four vertically arranged support rods. A lens fixing hole is vertically penetrated through the camera tray. A perspective through hole is vertically penetrated through the top support plate corresponding to the lens fixing hole. This setting has a simple structure and provides sufficient support and good guiding for the sample placing and adjusting component. The sample placing and adjusting component includes a fixed cylinder body. The middle periphery of the fixed cylinder body is fixedly embedded in the middle of the bottom support plate. A first sliding groove is opened on the inner wall of the fixed cylinder body. A first adjusting cylinder body is slidably arranged in the first sliding groove through a first sliding block correspondingly. A second sliding groove is opened on the inner wall of the first adjusting cylinder body. A second adjusting cylinder body is slidably arranged in the second sliding groove through a second sliding block correspondingly. The fixed end of an electric lifting rod is fixedly connected to the bottom inner wall of the fixed cylinder body. The moving end of the electric lifting rod is fixedly arranged on the top inner wall of the second adjusting cylinder body. Above the second adjusting cylinder body, a buffer connecting plate, a sample placing table, and a biological sample are correspondingly arranged from bottom to top in sequence. Four end parts of the sample placing table are correspondingly and slidably sleeved on the peripheries of the four guiding rods. This setting controls the electric lifting rod to rise (fall). As the rising (falling) height increases, it gradually drives the second adjusting cylinder body to slide upward (downward) in the second sliding groove through the second sliding block, and the first adjusting cylinder body to slide upward (downward) in the first sliding groove through the first sliding block, thereby sequentially driving the buffer connecting plate, the sample placing table, and the biological sample to rise (fall) synchronously, realizing the adjustment of the object distance between the biological sample and the camera lens. The whole process has a simple principle and is easy to adjust. The electric lifting rod drives the second adjusting cylinder body and the first adjusting cylinder body to vertically rise and fall, and combined with the guiding effect of the four guiding rods, the whole adjustment process is more stable.

[0015] 2. There is a control console at the bottom inside the equipment box of the present utility model. A controller is arranged inside the control console. There is a keypad corresponding to the control console outside the equipment box. The keypad is electrically connected to the controller. The controller can adopt a controller of the small-sized controller PNOZmulti2 model. This controller can be applicable to common communication networks and can also connect, control, and monitor multiple components simultaneously. This setting enables the normal operation of the entire device.

[0016] 3. A wire hole is provided at the bottom of the fixed cylinder body of the present utility model corresponding to the electric lifting rod. The electric lifting rod is electrically connected to the controller through the wire inside the wire hole. This setting enables the normal lifting of the electric lifting rod to realize the adjustment of the object distance between the biological sample and the camera lens.

[0017] 4. An observation window is provided on the front side of the equipment box of the present utility model. A grasping handle is correspondingly arranged on the observation window. This setting facilitates the real-time observation during the adjustment of the sample object distance and is also convenient for the regular maintenance of the components inside the equipment box.

[0018] 5. A rubber ring plate is provided above the fixed cylinder body of the present utility model corresponding to the outer edge of its top. This setting can make the upper end surface of the buffer connecting plate flush with the upper end surface of the rubber ring plate when the sample placement table descends to above the fixed cylinder body along with the buffer connecting plate. The buffer connecting plate and the rubber ring plate together play a buffering role when the descent of the sample placement table is completed.

[0019] 6. Both the buffer connecting plate and the sample placement table of the present utility model are horizontally arranged. This setting ensures that the sample placement table can always remain horizontal during the position movement adjustment process, effectively avoiding the slippage of the biological sample due to the inclination of the sample placement table during the position movement adjustment process, which may affect the subsequent imaging, and at the same time making the sample placement table more stable when it descends to the bottommost position.

[0020] 7. The length of the first sliding groove of the present utility model is greater than the length of the second sliding groove. This setting ensures that both the first adjusting cylinder body and the second adjusting cylinder body can be retracted into the fixed cylinder body. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 It is a front view structural schematic diagram of the present utility model;

[0022] Figure 2 It is an internal front view structural schematic diagram when the sample placement adjustment assembly of the present utility model is unfolded;

[0023] Figure 3 It is an internal front view structural schematic diagram when the sample placement adjustment assembly of the present utility model is folded;

[0024] Figure 4 It is a front view sectional structural schematic diagram when the sample placement adjustment assembly of the present utility model is unfolded;

[0025] Figure 5 This is a right - view cross - sectional structural schematic diagram when the sample placement adjustment assembly of the present utility model is folded;

[0026] Figure 6 This is a cross - sectional structural schematic diagram when the sample placement adjustment assembly of the present utility model is unfolded;

[0027] Figure 7 This is a cross - sectional structural schematic diagram when the sample placement adjustment assembly of the present utility model is folded.

[0028] Reference numerals: 1: equipment box body, 2: guiding and supporting assembly, 3: sample placement adjustment assembly, 4: bottom support plate, 5: guiding rod, 6: top support plate, 7: support rod, 8: camera tray, 9: lens fixing hole, 10: perspective through - hole, 11: fixed cylinder body, 12: first sliding groove, 13: first sliding block, 14: first adjustment cylinder body, 15: second sliding groove, 16: second sliding block, 17: second adjustment cylinder body, 18: electric lifting rod, 19: buffer connecting plate, 20: sample placement table, 21: biological sample, 22: control console, 23: controller, 24: keyboard, 25: wire hole, 26: wire, 27: observation window, 28: gripping handle, 29: rubber ring plate. Detailed implementation manners

[0029] Next, the technical solutions of the present utility model will be described clearly and completely in conjunction with the accompanying drawings. Obviously, the described embodiments are some, rather than all, of the embodiments of the present utility model. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without creative efforts shall fall within the protection scope of the present utility model.

[0030] In the description of the present utility model, it should be noted that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. is based on the orientation or positional relationship shown in the accompanying drawings. It is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus cannot be understood as a limitation to the present utility model. In addition, the terms "first", "second", "third" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance.

[0031] In the description of the present utility model, it should be noted that unless otherwise clearly specified and defined, the terms "installation", "connection", "linkage", and "setting" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, and it can be the communication inside two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific situations.

[0032] Such as Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 and Figure 7As shown in the figure, it includes an equipment box body 1, a guiding and supporting component 2 arranged inside the equipment box body 1, and a sample placement and adjustment component 3 arranged on the guiding and supporting component 2. This setting provides a space for placing and installing the guiding and supporting component 2 through the equipment box body 1, and provides a space for the movement and adjustment of the sample placement and adjustment component 3. The setting of the guiding and supporting component 2 lays a foundation for the installation of the sample placement and adjustment component 3 and the guiding during movement. The sample placement and adjustment component 3 is used to place the biological sample 21 and adjust the height of the biological sample 21. Generally speaking, compared with the previous position movement device for imaging biological samples 21, this position movement device for imaging biological samples 21 can adjust the sample placement and adjustment component 3 through a simple principle to meet the needs of different object distances during fixed-focus imaging, with a simple structure, easy to adjust, and more stable; The guiding and supporting component 2 includes a bottom support plate 4 horizontally arranged in the middle of the equipment box body 1. Four end parts of the bottom support plate 4 are correspondingly provided with guiding rods 5 vertically upward. Above the four guiding rods 5, a top support plate 6 is horizontally arranged correspondingly. Above the top support plate 6, a camera tray 8 is arranged through four vertically arranged support rods 7. A lens fixing hole 9 is opened through the camera tray 8 from top to bottom. A perspective through hole 10 is opened through the top support plate 6 correspondingly for the lens fixing hole 9 from top to bottom. This setting has a simple structure and provides sufficient support and good guidance for the sample placement and adjustment component 3; The sample placement and adjustment component 3 includes a fixed cylinder 11. The middle periphery of the fixed cylinder 11 is fixedly embedded in the middle of the bottom support plate 4. A first sliding groove 12 is opened on the inner wall of the fixed cylinder 11. A first adjusting cylinder 14 is slidably arranged in the first sliding groove 12 through a first sliding block 13 correspondingly. A second sliding groove 15 is opened on the inner wall of the first adjusting cylinder 14. A second adjusting cylinder 17 is slidably arranged in the second sliding groove 15 through a second sliding block 16 correspondingly. The fixed end of an electric lifting rod 18 is fixedly connected to the bottom inner wall of the fixed cylinder 11. The moving end of the electric lifting rod 18 is fixedly arranged on the top inner wall of the second adjusting cylinder 17. Above the second adjusting cylinder 17, a buffer connecting plate 19, a sample placement table 20, and a biological sample 21 are correspondingly arranged from bottom to top in sequence. Among them, four end parts of the sample placement table 20 are correspondingly sleeved on the outer periphery of the four guiding rods 5. This setting controls the electric lifting rod 18 to rise (fall). As the rising (falling) height increases, it gradually drives the second adjusting cylinder 17 to slide upward (downward) in the second sliding groove 15 through the second sliding block 16, and the first adjusting cylinder 14 to slide upward (downward) in the first sliding groove 12 through the first sliding block 13, and then drives the buffer connecting plate 19, the sample placement table 20, and the biological sample 21 to rise (fall) synchronously, realizing the adjustment of the object distance between the biological sample 21 and the camera lens. The whole process has a simple principle and is easy to adjust. The electric lifting rod 18 drives the second adjusting cylinder 17 and the first adjusting cylinder 14 to vertically rise and fall, and combined with the guiding effect of the four guiding rods 5, makes the whole adjustment process more stable.

[0033] As Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5 shown, a control console 22 is provided at the inner bottom of the equipment box body 1. A controller 23 is provided inside the control console 22. An operation panel 24 is provided outside the equipment box body 1 corresponding to the control console 22. The operation panel 24 is electrically connected to the controller 23. The controller 23 can adopt a controller 23 of the PNOZmu l t i2 model of a small controller 23. This controller 23 can be applied to common communication networks and can also connect, control, and monitor multiple components at the same time. This setting enables the entire device to operate normally.

[0034] As Figure 2 , Figure 3 , Figure 4 and Figure 5 shown, a wire hole 25 is provided at the bottom of the fixed cylinder body 11 corresponding to the electric lifting rod 18. The electric lifting rod 18 is electrically connected to the controller 23 through a wire 26 inside the wire hole 25. This setting enables the electric lifting rod 18 to lift and lower normally to adjust the object distance between the biological sample 21 and the camera lens.

[0035] As Figure 1 shown, an observation window 27 is provided on the front side of the equipment box body 1. A grip handle 28 is provided corresponding to the observation window 27. This setting facilitates the real-time observation during the adjustment of the sample object distance and is convenient for the regular maintenance of the components inside the equipment box body 1.

[0036] As Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 and Figure 7 shown, a rubber ring plate 29 is provided above the fixed cylinder body 11 corresponding to the outer edge of its top. This setting can make the upper end surface of the buffer connection plate 19 flush with the upper end surface of the rubber ring plate 29 when the sample placement table 20 descends to above the fixed cylinder body 11 along with the buffer connection plate 19. The buffer connection plate 19 and the rubber ring plate 29 together play a buffering role when the sample placement table 20 finishes descending.

[0037] As Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 and Figure 7As shown, the buffer connection plate 19 and the sample placement table 20 are both horizontally arranged. This arrangement ensures that the sample placement table 20 can always remain horizontal during the position movement adjustment process, effectively avoiding the slippage of the biological sample 21 due to the inclination of the sample placement table 20 during the position movement adjustment, which may affect subsequent imaging. At the same time, it can make the sample placement table 20 more stable when it descends to the bottommost position.

[0038] As Figure 4 , Figure 5 , Figure 6 and Figure 7 As shown, the length of the first sliding groove 12 is greater than the length of the second sliding groove 15. This arrangement ensures that both the first adjusting cylinder 14 and the second adjusting cylinder 17 can be retracted into the fixed cylinder 11.

[0039] The specific operation principle is as follows:

[0040] When using this biological sample imaging position movement device, first, it needs to be connected to an external power supply to make the electrical components on this device all in an operating state or a standby state. Grasp the grasping handle and pull the observation window outward to open it. Put the lens of the camera into the lens fixing hole and fix the camera to the camera tray. Fix the biological sample on the sample placement table and align it with the camera lens. Then grasp the grasping handle and push the observation window inward to close it. Click the keyboard, and through the controller, control the electric lifting rod to rise (descend). As the rising (descending) height increases, gradually drive the second adjusting cylinder to slide upward (downward) in the second sliding groove through the second slider, and drive the first adjusting cylinder to slide upward (downward) in the first sliding groove through the first slider. Furthermore, drive the buffer connection plate to rise (descend) vertically, and the sample placement table synchronously rises (descends) vertically under the guiding action of the four guiding rods, thereby driving the biological sample to synchronously rise (descend) vertically, realizing the adjustment of the object distance between the biological sample and the camera lens.

[0041] The electrical components mentioned in this article can all be electrically connected to the external main controller and 220V mains through a transformer. And the main controller can be a conventional known device such as a computer that plays a control role. A conventional known device such as a computer that plays a control role can receive various data signals monitored by this device in real time. The electrical components provided by the present invention are only used according to the structural characteristics of the technical solution. Its products will be adjusted and modified after purchase to make them more matching and conforming to the technical solution of the present invention. It is an optimal application technical solution of this technical solution. The model of its products can be replaced and modified according to the required technical parameters. It is well-known to those skilled in the art. Therefore, those skilled in the art can clearly obtain the corresponding use effects through the technical solution provided by the present invention.

[0042] The control mode of the present utility model is automatically controlled by a controller. The control circuit of the controller can be realized by simple programming of those skilled in the art. The provision of power also belongs to the common general knowledge in the art. And the present utility model is mainly used to protect mechanical devices. Therefore, the control mode and circuit connection of the present utility model will not be explained in detail.

[0043] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present utility model, rather than to limit them; although the present utility model has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that they can still modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements on some or all of the technical features; and these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present utility model.

Claims

1. A position motion device for biological sample imaging, characterized in that: It comprises an equipment box, a guide support component arranged in the equipment box, and a sample placement adjustment component arranged on the guide support component; The guide support assembly comprises a bottom support plate horizontally arranged in the middle of the equipment box, four ends of the bottom support plate are vertically arranged with guide rods, a top support plate is horizontally arranged above the four guide rods, a camera tray is arranged above the top support plate through four vertically arranged support rods, a lens fixing hole is opened through the camera tray from top to bottom, and a perspective through hole is opened on the top support plate from top to bottom corresponding to the lens fixing hole; The sample placement and adjustment assembly includes a fixed cylinder, the middle periphery of the fixed cylinder is fixedly embedded in the middle of the bottom support plate, a first slide groove is opened on the inner wall of the fixed cylinder, a first adjustment cylinder is slidably arranged in the first slide groove through the first sliding block, a second slide groove is opened on the inner wall of the first adjustment cylinder, a second adjustment cylinder is slidably arranged in the second slide groove through the second sliding block, the bottom inner wall of the fixed cylinder is fixedly connected to the fixed end of the electric lifting rod, the movable end of the electric lifting rod is fixedly arranged on the top inner wall of the second adjustment cylinder, and a buffer connecting plate, a sample placement table and a biological sample are correspondingly arranged above the second adjustment cylinder from bottom to top, wherein the four ends of the sample placement table are correspondingly slidably sleeved on the periphery of the four guide rods.

2. A position movement device for biological sample imaging according to claim 1, characterized in that: A control console is arranged at the bottom of the equipment box, a controller is arranged in the control console, and a keyboard is arranged outside the equipment box corresponding to the control console, and the keyboard is electrically connected to the controller.

3. A position movement device for biological sample imaging according to claim 2, characterized in that: A wire hole is provided at the bottom of the fixed cylinder corresponding to the electric lifting rod, and the electric lifting rod is electrically connected to the controller through a wire in the wire hole.

4. A position movement device for biological sample imaging according to claim 1, characterized in that: An observation window is arranged on the front side of the equipment box, and a gripping handle is arranged correspondingly on the observation window.

5. The position movement device for biological sample imaging according to claim 1, characterized in that: A rubber ring plate is arranged above the fixed cylinder corresponding to the top outer edge thereof.

6. The position movement device for biological sample imaging according to claim 1, characterized in that: The buffer connection plate and the sample placement table are both arranged horizontally.

7. The position movement device for biological sample imaging according to claim 1, characterized in that: The length of the first slide groove is greater than the length of the second slide groove.

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