Integrated nucleic acid detection card box and nucleic acid detection equipment

By setting limiting components and closing components inside the waste liquid chamber of the nucleic acid detection card box, the problem of the waste liquid box slipping out is solved, and the efficiency of waste liquid collection and treatment is improved.

CN222893172UActive Publication Date: 2025-05-23QINGDAO AGRI UNIV +1
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Patent Information

Application Number
CN202421728748.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-07-22
Publication Date
2025-05-23
Estimated Expiration
2034-07-22

AI Technical Summary

Technical Problem

During the nucleic acid testing process of existing nucleic acid testing cartridges, the waste liquid box is prone to slide out from the inside of the waste liquid chamber due to the tilt of the main body of the cartridge, affecting the collection of waste liquid.

Method used

An integrated nucleic acid detection card box is designed. By setting limit components inside the waste liquid chamber, the stability of the connection between the waste liquid chamber and the waste liquid chamber is increased, and the waste liquid chamber is prevented from slipping out. At the same time, the connecting pipe is closed and sealed using a closed component to facilitate the transfer and treatment of waste liquid inside the waste liquid box.

Benefits of technology

It effectively prevents the waste liquid box from sliding out when the main body of the card box is tilted, improves the waste liquid collection efficiency, and simplifies the operation process of waste liquid treatment through the design of the closed components.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of nucleic acid detection equipment, in particular to an integrated nucleic acid detection card box and nucleic acid detection equipment, which comprise a card box main body, a connecting shell is arranged on the outer side of the card box main body, a waste liquid bin is arranged in the connecting shell, and a waste liquid box is arranged in the waste liquid bin. Limiting assemblies are arranged at the two ends in the waste liquid bin, the waste liquid box is connected with the waste liquid bin through the limiting assemblies, a connecting pipe is arranged at the end, close to the waste liquid bin, of the waste liquid box, and a closing assembly is arranged in the connecting pipe; the limiting assembly is used for improving the connection stability of the waste liquid box and the waste liquid bin; compared with the existing detection card box, the detection card box disclosed by the utility model has the advantage that the overall practicability of the detection card box can be improved through the design.
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Description

Technical Field

[0001] The utility model relates to the technical field of nucleic acid detection equipment, and in particular to an integrated nucleic acid detection card box and nucleic acid detection equipment. Background Art

[0002] Currently, most tests for molecular diagnosis, morphology, immunology, etc. are carried out in professional laboratories. The traditional detection process generally includes the following steps: first, nucleic acid amplification is performed in large and medium-sized detection equipment; then the amplified nucleic acid is manually transferred to the electrophoresis detection equipment for electrophoresis detection; finally, the electrophoresis detection results are manually transferred to a dedicated fluorescence analyzer for result analysis.

[0003] After searching, announcement number CN218290922U discloses an integrated nucleic acid detection card box and nucleic acid detection equipment, which relates to the technical field of nucleic acid detection equipment, including a nucleic acid detection card box body and a waste liquid bin, a waste liquid box, a second pipe, a first pipe, a first sealing rubber, and a sealing mechanism. The utility model sets a sealing mechanism and an auxiliary mechanism. When the waste liquid box is fully installed inside the waste liquid bin, the fixation between the rotating shaft and the connecting seat is released by the auxiliary mechanism, and the torsion spring drives the cover plate to rotate through the rotating shaft, so that the cover plate is pressed against the outer wall of the first pipe, and the waste liquid box is pulled out of the waste liquid bin. When the first pipe is separated from the second pipe, the torsion spring drives the cover plate to reset through the rotating shaft, so that the cover plate rotates to one end of the second pipe, so that the second sealing rubber is inserted into the second pipe, and the rotating shaft and the connecting seat are fixed by the auxiliary mechanism, so as to facilitate the staff to directly put the waste liquid into the waste liquid bin. The function of transferring the waste liquid inside the liquid box to a designated location for treatment makes it convenient for the staff to operate; its defect is that when the waste liquid box in this scheme is connected to the waste liquid bin, the waste liquid box is limited only by the outer side of the waste liquid box fitting with the inner side of the waste liquid bin. When the main body of the nucleic acid detection card box is tilted, the waste liquid box is easy to slide out from the inside of the waste liquid bin, affecting the collection of the waste liquid. Therefore, it is particularly important to improve the existing detection card box and design a new integrated nucleic acid detection card box and nucleic acid detection equipment to solve the above-mentioned technical defects and improve the practicability of the overall detection card box. Utility Model Content

[0004] The purpose of the utility model is to provide an integrated nucleic acid detection card box and a nucleic acid detection device. When the waste liquid box is connected to the waste liquid bin, the stability of the connection between the waste liquid box and the waste liquid bin can be increased by a limiting component. When the card box body is tilted, the waste liquid box is prevented from sliding from the inside of the waste liquid bin and affecting the collection of the waste liquid, so as to solve the problems raised in the above-mentioned background technology.

[0005] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0006] An integrated nucleic acid detection cartridge comprises a cartridge body, a connecting shell is arranged on the outside of the cartridge body, a waste liquid bin is provided inside the connecting shell, a waste liquid box is provided inside the waste liquid bin, and both ends of the waste liquid bin are provided with limit assemblies, the waste liquid box is connected to the waste liquid bin through the limit assemblies, and a connecting tube is provided at one end of the waste liquid box close to the waste liquid bin, and a closing assembly is provided inside the connecting tube;

[0007] The limiting assembly is used to increase the stability of the connection between the waste liquid box and the waste liquid bin;

[0008] The closing assembly is used to close the connecting pipe.

[0009] As a preferred solution of the utility model, the limit assembly consists of a fixed frame, a limit rod, a moving block, an arc groove, a rotating rod, a sliding block and a connecting rod. The fixed frame is located inside the waste liquid bin and on the outside of the waste liquid box. Two groups of limit rods are located inside the fixed frame and close to one end of the waste liquid box. The moving block is slidably connected to the inside of the fixed frame and is located between the two groups of limit rods. Multiple groups of arc grooves are opened on the outside of the fixed frame. The two groups of rotating rods are rotatably connected to one end of the moving block away from the limit rod. The sliding block is rotatably connected to one end of the rotating rod away from the moving block, and the connecting rod is located inside the two groups of sliding blocks.

[0010] As a preferred solution of the utility model, a guide groove is opened on the outer side of the arc groove, and the limiting rod extends to the arc groove and the guide groove and is provided with a guide block inside. The internal structure size of the guide block is designed to correspond to the internal structure size of the guide groove and the arc groove.

[0011] As a preferred solution of the utility model, grooves are provided at both ends of the moving block, and a protrusion is provided at the end of the limiting rod close to the moving block. The external structure size of the protrusion is designed to correspond to the internal structure size of the groove, and the limiting rod is connected to the groove through the protrusion.

[0012] As a preferred solution of the utility model, the sliding block is slidably connected to the connecting rod, and compression springs are provided at both ends of the connecting rod and located outside the two groups of sliding blocks. The compression springs are connected to the sliding block through the connecting rod.

[0013] As a preferred solution of the utility model, two sets of limit grooves are opened at one end of the waste liquid box close to the waste liquid bin, the internal structure size of the limit grooves is designed to correspond to the external structure size of the limit rod, and the waste liquid box is connected to the limit rod through the limit grooves.

[0014] As a preferred solution of the utility model, the closing assembly consists of a rotating disk, a driving rod, an engaging groove, a closing plate and an engaging strip, the rotating disk is rotatably connected to the top of the connecting tube, the driving rod is rotatably connected to the top of the connecting tube and is located on the outside of the rotating disk, the engaging groove is opened at the end of the driving rod away from the rotating disk, the closing plate is fixedly connected to the bottom of the rotating disk and is located inside the connecting tube, and the engaging strip is fixedly connected to the inside of the waste liquid bin and close to one end of the driving rod.

[0015] As a preferred solution of the utility model, a driving groove is opened at one end of the driving rod close to the rotating disk, and the rotating disk extends to the inside of the driving groove and is fixedly connected with a fixing rod, and the rotating disk is connected to the driving groove through the fixing rod, and the meshing groove is meshingly connected to the meshing strip.

[0016] A second aspect of the present invention provides a nucleic acid detection device, comprising the integrated nucleic acid detection card box as described in the above embodiment.

[0017] Compared with the prior art, the beneficial effects of the utility model are:

[0018] 1. In the utility model, through the design of the limit component, when the waste liquid box is connected to the waste liquid bin, the limit component can increase the stability of the connection between the waste liquid box and the waste liquid bin. When the card box body is tilted, the waste liquid box is prevented from sliding from the inside of the waste liquid bin to affect the collection of waste liquid.

[0019] 2. In the utility model, through the design of the closing component, when the waste liquid box is moved out from the inner position of the waste liquid bin, the connecting pipe can be closed and sealed through the closing component, so that the waste liquid inside the waste liquid box can be easily transferred to the designated location for treatment, which is convenient for the staff to operate. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0021] Figure 2 This is a schematic diagram of the internal structure of the waste liquid bin of the utility model;

[0022] Figure 3 This is a schematic diagram of the structure of the limit assembly of the utility model;

[0023] Figure 4 This is a schematic diagram of the structure of the mobile block of the utility model;

[0024] Figure 5 This is a schematic diagram of the structure of the waste liquid box of the utility model;

[0025] Figure 6 This is a schematic diagram of the structure of the closed component of the utility model.

[0026] In the figure: 1. Card box body; 2. Connecting shell; 3. Waste liquid bin; 4. Waste liquid box; 5. Limiting assembly; 6. Connecting pipe; 7. Closing assembly; 8. Fixed frame; 9. Limiting rod; 10. Moving block; 11. Arc groove; 12. Rotating rod; 13. Sliding block; 14. Connecting rod; 15. Guide groove; 16. Guide block; 17. Compression spring; 18. Limiting groove; 19. Rotating disk; 20. Driving rod; 21. Engaging groove; 22. Closing plate; 23. Engaging strip; 24. Driving groove; 25. Fixed rod. DETAILED DESCRIPTION

[0027] The technical solutions in the embodiments of the utility model will be clearly and completely described below in conjunction with the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the utility model.

[0028] Example:

[0029] See also Figure 1-Figure 6 , the utility model provides a technical solution:

[0030] An integrated nucleic acid detection cartridge comprises a cartridge body 1, a connecting shell 2 is provided on the outside of the cartridge body 1, a waste liquid bin 3 is provided inside the connecting shell 2, a waste liquid box 4 is provided inside the waste liquid bin 3, and both ends of the waste liquid bin 3 are provided with limit assemblies 5, the waste liquid box 4 is connected to the waste liquid bin 3 through the limit assemblies 5, and a connecting tube 6 is provided at one end of the waste liquid box 4 close to the waste liquid bin 3, and a closing assembly 7 is provided inside the connecting tube 6;

[0031] The limiting component 5 is used to increase the stability of the connection between the waste liquid box 4 and the waste liquid bin 3;

[0032] Furthermore, the limiting assembly 5 is composed of a fixed frame 8, a limiting rod 9, a moving block 10, an arc groove 11, a rotating rod 12, a sliding block 13 and a connecting rod 14. The fixed frame 8 is located inside the waste liquid bin 3 and outside the waste liquid box 4. Two groups of limiting rods 9 are both located inside the fixed frame 8 and close to one end of the waste liquid box 4. The moving block 10 is slidably connected to the inside of the fixed frame 8 and is located between the two groups of limiting rods 9. Multiple groups of arc grooves 11 are all opened on the outside of the fixed frame 8. Two groups of rotating rods 12 are rotatably connected to one end of the moving block 10 away from the limiting rod 9. The sliding block 13 is rotatably connected to one end of the rotating rod 12 away from the moving block 10. The connecting rod 14 is located inside the two groups of sliding blocks 13. When the waste liquid box 4 is connected to the waste liquid bin 3, the limiting assembly 5 can increase the stability of the connection between the waste liquid box 4 and the waste liquid bin 3. When the card box body 1 is tilted, the waste liquid box 4 is prevented from slipping from the inside of the waste liquid bin 3, affecting the collection of waste liquid.

[0033] Among them, a guide groove 15 is opened on the outer side of the arc groove 11, and the limit rod 9 extends to the arc groove 11 and the guide groove 15. A guide block 16 is provided inside the guide block 16. The internal structure size of the guide block 16 is designed to correspond to the internal structure size of the guide groove 15 and the arc groove 11. Multiple groups of guide blocks 16 are slidingly connected to the arc groove 11 and the guide groove 15 respectively, so that the limit rod 9 can be slidingly connected to the arc groove 11 and the guide groove 15. When the limit rod 9 is displaced, the limit rod 9 can be displaced and rotated through the arc groove 11. At the same time, when the limit rod 9 is displaced, it can be guided by the guide groove 15 to prevent the limit rod 9 from being offset.

[0034] Secondly, grooves are provided at both ends of the moving block 10, and a protrusion is provided at the end of the limiting rod 9 close to the moving block 10. The external structure size of the protrusion is designed to correspond to the internal structure size of the groove. The limiting rod 9 is connected to the groove through the protrusion, and the groove is connected to the protrusion. When the moving block 10 is displaced, the protrusion can be displaced through the groove, driving the limiting rod 9 to be displaced.

[0035] Furthermore, the sliding block 13 and the connecting rod 14 are slidably connected. Compression springs 17 are provided at both ends of the connecting rod 14 and on the outside of the two groups of sliding blocks 13. The compression spring 17 is connected to the sliding block 13 through the connecting rod 14. The sliding block 13 and the connecting rod 14 are slidably connected, so that the sliding block 13 can be connected to the compression spring 17. The compression spring 17 drives the sliding block 13 to move, so that the rotating rod 12 can move, driving the moving block 10 to move.

[0036] Furthermore, two sets of limiting grooves 18 are provided at one end of the waste liquid box 4 close to the waste liquid bin 3. The internal structure size of the limiting grooves 18 is designed to correspond to the external structure size of the limiting rod 9. The waste liquid box 4 is connected to the limiting rod 9 through the limiting grooves 18, and the limiting rod 9 is limitedly connected to the limiting grooves 18, so that the limiting rod 9 can be limitedly connected to the waste liquid box 4, thereby limiting the waste liquid box 4 inside the waste liquid bin 3.

[0037] The closing component 7 is used to close the connecting pipe 6;

[0038] Furthermore, the closing component 7 is composed of a rotating disk 19, a driving rod 20, an engaging groove 21, a closing plate 22 and an engaging strip 23. The rotating disk 19 is rotatably connected to the top of the connecting tube 6, the driving rod 20 is rotatably connected to the top of the connecting tube 6 and is located on the outside of the rotating disk 19, the engaging groove 21 is opened at the end of the driving rod 20 away from the rotating disk 19, the closing plate 22 is fixedly connected to the bottom of the rotating disk 19 and is located inside the connecting tube 6, the engaging strip 23 is fixedly connected to the inside of the waste liquid bin 3 and close to one end of the driving rod 20. When the waste liquid box 4 is moved out from the inner position of the waste liquid bin 3, the connecting tube 6 can be closed and sealed by the closing component 7, so that the waste liquid in the waste liquid box 4 can be transferred to the designated position for treatment, which is convenient for the staff to operate.

[0039] Furthermore, a driving groove 24 is opened at one end of the driving rod 20 close to the rotating disk 19, and the rotating disk 19 extends to the inside of the driving groove 24 and is fixedly connected with a fixing rod 25, and the rotating disk 19 is connected to the driving groove 24 through the fixing rod 25, and the meshing groove 21 and the meshing bar 23 are meshingly connected. When the waste liquid box 4 moves out of the interior of the waste liquid bin 3, the connecting tube 6 is driven to move, so that the driving rod 20 can be moved. The meshing connection between the meshing groove 21 and the meshing bar 23 enables the driving rod 20 to rotate through the meshing bar 23, and cooperates with the fixing rod 25 extending to the inside of the driving groove 24 to drive the rotating disk 19 to rotate, so that the closing plate 22 can rotate, and the interior of the connecting tube 6 is closed and sealed.

[0040] When the hopper 10 is in a state of being moved, the hopper 10 is moved in a direction of rotation to move the hopper 10 in a direction of rotation, so that the hopper 10 can move freely, and the hopper 10 can move freely. When the waste liquid box 4 needs to be taken out from the interior of the waste liquid bin 3, the waste liquid box 4 is slightly displaced, the limiting rod 9 is squeezed, and the sliding block 13 is driven to displace by the compression spring 17, so that the rotating rod 12 can be displaced, and the moving block 10 is driven to be displaced, and the moving block 10 is reset so that the limiting rod 9 can be opened and closed, thereby the waste liquid box 4 can be moved out of the interior of the waste liquid bin 3. When the waste liquid box 4 is moved out of the interior of the waste liquid bin 3, the connecting tube 6 is driven to be displaced, so that the driving rod 20 can be displaced, and the meshing groove 21 is meshed with the meshing strip 23. The driving rod 20 can be rotated through the meshing strip 23, and the fixed rod 25 extending to the inside of the driving groove 24 drives the rotating disk 19 to rotate, so that the closing plate 22 can rotate, and the interior of the connecting tube 6 is closed and sealed. Compared with the existing detection cartridge, the utility model can improve the overall practicality of the detection cartridge through design.

[0041] The utility model also provides a nucleic acid detection device, including the integrated nucleic acid detection card box as described in the above embodiment. The content of the integrated nucleic acid detection card box can be found in the above description and will not be repeated here.

[0042] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An integrated nucleic acid detection cartridge, comprising a cartridge body (1), characterized in that: A connecting shell (2) is provided on the outside of the card box body (1), a waste liquid bin (3) is provided inside the connecting shell (2), a waste liquid box (4) is provided inside the waste liquid bin (3), and both ends of the waste liquid bin (3) are provided with limit assemblies (5), the waste liquid box (4) is connected to the waste liquid bin (3) through the limit assemblies (5), and a connecting pipe (6) is provided at one end of the waste liquid box (4) close to the waste liquid bin (3), and a closing assembly (7) is provided inside the connecting pipe (6); The limiting component (5) is used to increase the stability of the connection between the waste liquid box (4) and the waste liquid bin (3); The closing component (7) is used to close the connecting pipe (6).

2. An integrated nucleic acid detection cartridge according to claim 1, characterized in that: The limiting assembly (5) is composed of a fixed frame (8), a limiting rod (9), a moving block (10), an arc groove (11), a rotating rod (12), a sliding block (13) and a connecting rod (14); the fixed frame (8) is located inside the waste liquid bin (3) and outside the waste liquid box (4); the two groups of limiting rods (9) are both located inside the fixed frame (8) and close to one end of the waste liquid box (4); the moving block (10) is slidably connected to the inside of the fixed frame (8) and is located between the two groups of limiting rods (9); a plurality of groups of arc grooves (11) are all opened on the outside of the fixed frame (8); the two groups of rotating rods (12) are both rotatably connected to one end of the moving block (10) away from the limiting rod (9); the sliding block (13) is rotatably connected to one end of the rotating rod (12) away from the moving block (10); and the connecting rod (14) is located inside the two groups of sliding blocks (13).

3. An integrated nucleic acid detection cartridge according to claim 2, characterized in that: A guide groove (15) is provided on the outer side of the arc groove (11), and a guide block (16) is provided inside the limit rod (9) extending to the arc groove (11) and the guide groove (15), and the internal structure size of the guide block (16) is designed to correspond to the internal structure size of the guide groove (15) and the arc groove (11).

4. The integrated nucleic acid detection cartridge according to claim 2, characterized in that: Both ends of the moving block (10) are provided with grooves, and the end of the limiting rod (9) close to the moving block (10) is provided with a protrusion, the external structure size of the protrusion is designed to correspond to the internal structure size of the groove, and the limiting rod (9) is connected to the groove through the protrusion.

5. The integrated nucleic acid detection cartridge according to claim 2, characterized in that: The sliding block (13) and the connecting rod (14) are slidably connected, and compression springs (17) are provided at both ends of the connecting rod (14) and located outside the two groups of sliding blocks (13). The compression springs (17) are connected to the sliding block (13) through the connecting rod (14).

6. The integrated nucleic acid detection cartridge according to claim 2, characterized in that: Two groups of limiting grooves (18) are provided at one end of the waste liquid box (4) close to the waste liquid bin (3); the internal structure size of the limiting grooves (18) is designed to correspond to the external structure size of the limiting rod (9); and the waste liquid box (4) is connected to the limiting rod (9) via the limiting grooves (18).

7. The integrated nucleic acid detection cartridge according to claim 1, characterized in that: The closing assembly (7) is composed of a rotating disk (19), a driving rod (20), an engaging groove (21), a closing plate (22) and an engaging strip (23); the rotating disk (19) is rotatably connected to the top of the connecting tube (6); the driving rod (20) is rotatably connected to the top of the connecting tube (6) and is located on the outside of the rotating disk (19); the engaging groove (21) is opened at one end of the driving rod (20) away from the rotating disk (19); the closing plate (22) is fixedly connected to the bottom of the rotating disk (19) and is located inside the connecting tube (6); the engaging strip (23) is fixedly connected to the inside of the waste liquid bin (3) and close to one end of the driving rod (20).

8. The integrated nucleic acid detection cartridge according to claim 6, characterized in that: A driving groove (24) is formed at one end of the driving rod (20) close to the rotating disk (19); a fixing rod (25) is fixedly connected to the interior of the driving groove (24) extending from the rotating disk (19); the rotating disk (19) is connected to the driving groove (24) via the fixing rod (25); and the meshing groove (21) is meshingly connected to the meshing bar (23).

9. A nucleic acid detection device, characterized in that: Comprising an integrated nucleic acid detection card box as described in any one of claims 1-8.

Citation Information

Patent Citations

  • Integrated nucleic acid detection card box and nucleic acid detection equipment

    CN218290922U