Multi-directional movement mixer for biological agents

Abstract

The utility model discloses a biological agent multidirectional movement mixer which comprises a fixed plate, a mixing tank arranged at the bottom of the fixed plate, four agent barrels arranged on the fixed plate, reciprocating electric push rods arranged on the agent barrels, piston pieces connected with the reciprocating electric push rods, material guide pipes communicated with the bottoms of the agent barrels, four butt joint pipes arranged on the mixing tank, and a plurality of butt joint pipes arranged on the butt joint pipes. And a rotating rod is arranged in the material mixing tank, a plurality of mixing plates are arranged on the rotating rod, and a plurality of mixing grooves are formed in the mixing plates. The reciprocating electric push rod drives the piston piece to reciprocate up and down in the medicament cylinder, so that the biological medicament is driven to be repeatedly filled into the mixing tank, the mixing plate rotates under the pushing action of the biological medicament to drive the biological medicament to be mixed, and the liquid level of the biological medicament is positioned in the medicament cylinder, so that the biological medicament can be uniformly mixed. Therefore, the biological agent in the mixing tank does not generate bubbles in the mixing process, so that acceleration of oxidation of the biological agent is avoided, and the use effect of the biological agent is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of liquid mixing, in particular to a multi-directional movement mixer for biological agents. Background Art

[0002] Biological agents are biological activation preparations prepared from microorganisms as starting materials. In the field of biopharmaceuticals, it is often necessary to mix and stir multiple biological agents. However, most of the existing biological agent mixing devices use an electric motor to drive a stirring device to rotate at a high speed in a container to mix and stir biological agents. Since there is still air in the container, a large number of bubbles will be generated under the action of high-speed rotation of the biological agents. The generated bubbles are mixed in the biological agents, which easily leads to accelerated oxidation of the biological agents and affects the use effect of the biological agents. Content of the Utility Model

[0003] The purpose of the utility model is to provide a multi-directional movement mixer for biological agents aiming at the deficiencies of the prior art, so as to solve the problems raised in the background art.

[0004] To achieve this purpose, the utility model adopts the following technical solutions:

[0005] A multi-directional movement mixer for biological agents includes a fixed plate. A mixing tank is arranged at the bottom of the fixed plate. Four vertically downward medicine cylinders are fixedly arranged at the central positions of the outer walls of the four sides of the fixed plate. A reciprocating electric push rod is arranged at the top of the medicine cylinder. The output shaft of the reciprocating electric push rod is fixedly provided with a piston sheet through a coupling. The outer wall of the piston sheet is slidably connected with the inner wall of the medicine cylinder. One end of the bottom of the medicine cylinder is communicated with a guide pipe. A first valve is installed on the guide pipe. The outer wall of the mixing tank is communicated with four equally spaced connecting pipes through openings. A pipe joint is fixedly arranged on the outer wall of one end of the connecting pipe. The connecting pipe is communicated with the guide pipe through the pipe joint. A vertical rotating rod is arranged at the central position of the mixing tank. Bearings are fixedly arranged on the outer walls of the top and bottom of the rotating rod. The central positions of the top and bottom of the mixing tank are movably connected with the outer walls of the bearings through openings. Equally spaced mixing plates are fixedly arranged on the outer wall of the rotating rod. Equally spaced mixing grooves are arranged on the outer wall of the mixing plate.

[0006] As a preferred scheme of the multi-directional movement mixer for biological agents, first fixing rings are fixedly arranged on the outer walls of the top of the medicine cylinder and the bottom of the reciprocating electric push rod respectively. The first fixing rings are fixedly connected through a bracket. The reciprocating electric push rod is conveniently fixed at the top of the medicine cylinder through the first fixing rings.

[0007] As a preferred scheme of the multi-directional movement mixer for biological agents, a feed pipe is communicated with one side of the bottom of the medicine cylinder. A feed valve is installed on the outer wall of the feed pipe. The biological agent is conveniently added into the medicine cylinder through the feed pipe.

[0008] As a preferred embodiment of the multi-directional motion mixer for biopharmaceuticals, a storage tank is provided at the bottom of the mixing tank. A connecting pipe is connected through an opening at the central position of the bottom of the mixing tank. One end of the bottom of the connecting pipe is connected to the top of the storage tank, and a second valve is installed on the outer wall of the connecting pipe.

[0009] As a preferred embodiment of the multi-directional motion mixer for biopharmaceuticals, a discharge pipe is connected to the central position of the outer wall at the bottom of the storage tank, and a discharge valve is installed on the outer wall of the discharge pipe. The storage tank facilitates the storage of the mixed biopharmaceuticals.

[0010] As a preferred embodiment of the multi-directional motion mixer for biopharmaceuticals, vertically downward support legs are fixedly provided at the four corners of the bottom of the fixed plate at equal intervals. The support legs facilitate placing the present invention in a designated position. A second fixing ring is fixedly provided on the outer wall at the bottom of the storage tank, and the outer wall of the second fixing ring is fixedly connected to the outer wall of the support legs through a bracket. The second fixing ring facilitates fixing the storage tank in a designated position.

[0011] Advantages of the present invention:

[0012] In the present invention, the output shaft of the reciprocating electric push rod drives the piston plate to reciprocate up and down on the inner wall of the medicine cylinder. The liquid level of the biopharmaceutical fluctuates up and down on the inner wall of the medicine cylinder, and at the same time drives the biopharmaceutical to be repeatedly filled into the mixing tank. Under the pushing action of the biopharmaceutical, the mixing plate will rotate, thereby driving the biopharmaceutical in the mixing tank to be mixed. Since the liquid level of the biopharmaceutical is inside the medicine cylinder, no bubbles will be generated during the mixing process of the biopharmaceutical in the mixing tank, thus avoiding accelerating the oxidation of the biopharmaceutical and being beneficial to improving the use effect of the biopharmaceutical. Description of the drawings

[0013] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required to be used in the embodiments of the present invention will be briefly introduced below. Obviously, the following described drawings are only some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0014] Figure 1 is the overall structural schematic diagram of the multi-directional motion mixer for biopharmaceuticals described in the present invention.

[0015] Figure 2 is the structural schematic diagram of the medicine cylinder described in the present invention.

[0016] Figure 3 is the partial sectional structural schematic diagram of the medicine cylinder described in the present invention.

[0017] Figure 4 It is a schematic structural diagram of the mixing tank described in the present utility model.

[0018] Figure 5 It is a schematic partial sectional structure diagram of the mixing tank described in the present utility model.

[0019] In the figure:

[0020] 1. Fixed plate; 2. Mixing tank; 3. Reagent cylinder; 4. Reciprocating electric push rod; 5. Piston piece; 6. First fixing ring; 7. Feed pipe; 8. Feed valve; 9. Guide pipe; 10. First valve; 11. Docking pipe; 12. Pipe joint; 13. Rotating rod; 14. Bearing; 15. Mixing plate; 16. Mixing tank; 17. Connecting pipe; 18. Second valve; 19. Storage tank; 20. Discharge pipe; 21. Discharge valve; 22. Support leg; 23. Second fixing ring. Specific embodiments

[0021] The technical solution of the present utility model will be further described below in conjunction with the accompanying drawings and through specific embodiments.

[0022] Among them, the accompanying drawings are only for illustrative purposes, showing only schematic diagrams, not physical diagrams, and should not be construed as a limitation of this patent; in order to better illustrate the embodiments of the present utility model, some components in the accompanying drawings will be omitted, enlarged or reduced, and do not represent the dimensions of the actual product; for those skilled in the art, it is understandable that some well-known structures and their descriptions in the accompanying drawings may be omitted.

[0023] In the accompanying drawings of the embodiments of the present utility model, the same or similar reference numerals correspond to the same or similar components; in the description of the present utility model, it should be understood that if terms such as "upper", "lower", "left", "right", "inner", "outer", etc. are used to indicate the orientation or positional relationship, it is based on the orientation or positional relationship shown in the accompanying drawings. It is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, the terms describing the positional relationship in the accompanying drawings are only for illustrative purposes and should not be construed as a limitation of this patent. For those of ordinary skill in the art, the specific meanings of the above terms can be understood according to specific circumstances.

[0024] In the description of the present utility model, unless otherwise clearly defined and limited, if terms such as "connection" are used to indicate the connection relationship between components, such terms shall be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral body; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two components or the interaction relationship between two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific circumstances.

[0025] Embodiment 1

[0026] As Figures 1 to 5 shown, this embodiment provides a multi-directional movement mixer for biological agents, including a fixed plate 1. A mixing tank 2 is provided at the bottom of the fixed plate 1. Four vertically downward medicine cylinders 3 are fixedly provided at the central positions of the outer walls of the four sides of the fixed plate 1. A reciprocating electric push rod 4 is provided at the top of the medicine cylinder 3. The output shaft of the reciprocating electric push rod 4 is fixedly provided with a piston piece 5 through a coupling. The outer wall of the piston piece 5 is slidably connected to the inner wall of the medicine cylinder 3. One end of the bottom of the medicine cylinder 3 is communicated with a guide pipe 9. A first valve 10 is installed on the guide pipe 9. The outer wall of the mixing tank 2 is communicated through an opening with four equally spaced docking pipes 11. A pipe joint 12 is fixedly provided on the outer wall of one end of the docking pipe 11. The docking pipe 11 is communicated with the guide pipe 9 through the pipe joint 12. A vertical rotating rod 13 is provided at the central position of the mixing tank 2. Bearings 14 are fixedly provided on the outer walls of the top and bottom of the rotating rod 13. The central positions of the top and bottom of the mixing tank 2 are movably connected to the outer walls of the bearings 14 through openings. Equally spaced mixing plates 15 are fixedly provided on the outer wall of the rotating rod 13. Equally spaced mixing grooves 16 are provided on the outer wall of the mixing plate 15.

[0027] Embodiment 2

[0028] Based on Embodiment 1, one side of the bottom of the medicine cylinder 3 in this embodiment is communicated with a feed pipe 7. A feed valve 8 is installed on the outer wall of the feed pipe 7. Through the feed pipe 7, it is convenient to add biological agents into the medicine cylinder 3. A storage tank 19 is provided at the bottom of the mixing tank 2. The central position of the bottom of the mixing tank 2 is communicated with a connecting pipe 17 through an opening. One end of the bottom of the connecting pipe 17 is communicated with the top of the storage tank 19. A second valve 18 is installed on the outer wall of the connecting pipe 17. A discharge pipe 20 is communicated with the central position of the outer wall of the bottom of the storage tank 19. A discharge valve 21 is installed on the outer wall of the discharge pipe 20. Through the storage tank 19, it is convenient to store the mixed biological agents.

[0029] Embodiment 3

[0030] Based on Embodiment 1, on the outer wall of the top of the medicine cylinder 3 and the outer wall of the bottom of the reciprocating electric push rod 4 in this embodiment, first fixing rings 6 are fixedly provided. The first fixing rings 6 are fixedly connected through a bracket. The reciprocating electric push rod 4 is fixed to the top of the medicine cylinder 3 through the first fixing rings 6. Vertically downward support legs 22 are fixedly provided at the four corners of the bottom of the fixing plate 1 at equal intervals. The support legs 22 facilitate placing the present utility model at a designated position. A second fixing ring 23 is fixedly provided on the outer wall of the bottom of the storage tank 19. The outer wall of the second fixing ring 23 is fixedly connected to the outer wall of the support legs 22 through a bracket. The second fixing ring 23 facilitates fixing the storage tank 19 at a designated position.

[0031] The working principle of the present utility model:

[0032] Referring to the attached drawings of the specification Figures 1-5 When the present utility model is used, first open the feed valve 8. By driving the output shaft of the reciprocating electric push rod 4 to contract, the piston piece 5 is driven to rise on the inner wall of the medicine cylinder 3, and the biological medicine will be sucked into the medicine cylinder 3 under the action of negative pressure. Then open the first valve 10 provided on the guide pipe 9, and the biological medicine flows into the mixing tank 2 through the docking pipe 11, thus filling the mixing tank 2. The unmixed medicine and air are located in the medicine cylinder 3. At this time, the output shaft of the reciprocating electric push rod 4 drives the piston piece 5 to reciprocate up and down on the inner wall of the medicine cylinder 3, and the liquid level of the biological medicine fluctuates up and down on the inner wall of the medicine cylinder 3, and at the same time drives the biological medicine to be repeatedly filled into the mixing tank 2. Under the pushing action of the biological medicine, the mixing plate 15 will rotate, thus driving the biological medicine in the mixing tank 2 to be mixed. Since the liquid level of the biological medicine is located in the medicine cylinder 3, no bubbles will be generated during the mixing process of the biological medicine in the mixing tank 2, thus avoiding accelerating the oxidation of the biological medicine and being beneficial to improving the use effect of the biological medicine. After the biological medicine is mixed, open the second valve 18, and the mixed biological medicine in the mixing tank 2 is input into the storage tank 19 through the connecting pipe 17 for storage. When the biological medicine needs to be used, open the discharge valve 21, and the biological medicine stored in the storage tank 19 is discharged through the discharge pipe 20 and input into a designated container for storage and use.

[0033] It should be noted that the above specific implementation manners are only the preferred embodiments of the present utility model and the applied technical principles. Those skilled in the art should understand that various modifications, equivalent replacements, changes, etc. can be made to the present utility model. However, as long as these transformations do not deviate from the spirit of the present utility model, they should be within the protection scope of the present utility model. In addition, some terms used in the description and claims of this application are not restrictive, but are only for the convenience of description.

Claims

1. A multi-directional motion mixer for biological agents, characterized in that: The invention comprises a fixed plate (1), a mixing tank (2) is arranged at the bottom of the fixed plate (1), four medicine barrels (3) are fixedly arranged vertically downward at the central positions of the outer walls of the four sides of the fixed plate (1), a reciprocating electric push rod (4) is arranged at the top of the medicine barrel (3), a piston plate (5) is fixedly arranged on the output shaft of the reciprocating electric push rod (4) through a coupling, the outer wall of the piston plate (5) and the inner wall of the medicine barrel (3) are slidably connected, one end of the bottom of the medicine barrel (3) is connected to a material guide pipe (9), a first valve (10) is installed on the material guide pipe (9), and the outer wall of the mixing tank (2) is connected to four equidistantly spaced valves (11) through an opening. A butt joint (11) is provided on the outer wall of one end of the butt joint (11), and the butt joint (12) is fixedly provided with the material guide pipe (9) through the pipe joint (12). A vertical rotating rod (13) is provided at the central position of the mixing tank (2), and bearings (14) are fixedly provided at the top and bottom outer walls of the rotating rod (13). The top and bottom central positions of the mixing tank (2) are movably connected to the outer wall of the bearing (14) through openings. Mixing plates (15) distributed at equal distances are fixedly provided on the outer wall of the rotating rod (13), and mixing grooves (16) distributed at equal distances are opened on the outer wall of the mixing plate (15).

2. The biopharmaceutical multi-directional mixer according to claim 1, characterized in that: The top outer wall of the medicine barrel (3) and the bottom outer wall of the reciprocating electric push rod (4) are both fixedly provided with a first fixing ring (6), and the first fixing rings (6) are fixedly connected via a bracket.

3. The biopharmaceutical multi-directional mixer according to claim 1, characterized in that: One side of the bottom of the medicine barrel (3) is connected to a feed pipe (7), and a feed valve (8) is installed on the outer wall of the feed pipe (7).

4. The biopharmaceutical multi-directional mixer according to claim 1, characterized in that: A material storage tank (19) is provided at the bottom of the mixing tank (2); a connecting pipe (17) is connected to the central position of the bottom of the mixing tank (2) through an opening; one end of the bottom of the connecting pipe (17) is connected to the top of the material storage tank (19); and a second valve (18) is installed on the outer wall of the connecting pipe (17).

5. The biopharmaceutical multi-directional mixer according to claim 4, characterized in that: A discharge pipe (20) is connected to the center of the bottom outer wall of the storage tank (19), and a discharge valve (21) is installed on the outer wall of the discharge pipe (20).

6. The biopharmaceutical multi-directional mixer according to claim 4, characterized in that: The four corners of the bottom of the fixed plate (1) are fixedly provided with support legs (22) which are evenly spaced and vertically downward, and the bottom outer wall of the storage tank (19) is fixedly provided with a second fixing ring (23), and the outer wall of the second fixing ring (23) is fixedly connected to the outer wall of the support leg (22) through a bracket.

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