Inverted microscope capable of rapidly switching samples

By designing an automated slider and edge-pressing drive structure, the rapid switching and fixing of inverted microscope slides are achieved, which solves the problem of slow switching of samples in the prior art, improves observation efficiency and protects samples.

CN222913959UActive Publication Date: 2025-05-27YIZHENG (SHANGHAI) BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202422051113.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-23
Publication Date
2025-05-27
Estimated Expiration
2034-08-23

AI Technical Summary

Technical Problem

Existing inverted microscopes require manual removal and placing of slides when switching samples, resulting in slow switching speed and low efficiency, especially when large numbers of samples are observed, which may lead to adverse consequences in cellular or biological samples.

Method used

An inverted microscope including a microscope body, a slide chute, a switching rack and a fixing unit was designed. The switching frame is equipped with an inclined lifting slide and a pressing member, which realizes an automated slide fixing and de-fixing process through the driving structure, reducing manual operation.

Benefits of technology

The rapid switching and fixation of the slides are achieved, the observation efficiency is improved, the observation time is reduced, and the adverse consequences of the sample due to long-term observation are avoided.

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Abstract

The utility model relates to an inverted microscope capable of rapidly switching samples, which comprises a microscope main body, a sliding chute arranged on the microscope main body, a switching frame sliding in and out of the sliding chute, and at least two groups of fixing units arranged on the switching frame and used for fixing glass slides, the fixing unit comprises a sliding piece which is arranged in the switching frame and slides upwards in an inclined mode, an edge pressing piece is hinged to the upper end of the sliding piece, and the hinged position is located in the middle of the edge pressing piece. In the fixing process, the sliding part is pushed by the driving structure to realize the process of firstly lifting and then pressing, on the contrary, when the glass slides are not fixed, the sliding part and the edge pressing part are contracted in the switching frame, shielding cannot be formed to affect replacement of the glass slides, when one glass slide is observed, the other glass slide can be prepared in advance, and the time of observing the other glass slide is shortened. And the observation efficiency is greatly improved.
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Description

Technical Field

[0001] The utility model belongs to the field of microscopes, and particularly relates to an inverted microscope capable of quickly switching samples. Background Technique

[0002] An inverted microscope is a special microscope, and the positions of its objective lens and illumination system are inverted relative to those of a traditional upright microscope. The objective lens of the inverted microscope is located below the stage, while the illumination system is located above the stage. This design makes the inverted microscope particularly suitable for observing cultured living cells or other unfixed biological samples, because the samples can be directly placed on the stage without the need for peeling or sectioning.

[0003] When switching samples on the existing inverted microscope, it is necessary to remove the original slide from the pressure clip, place a new slide, and then continue to fix it through the pressure clip. The switching process wastes time. Especially when a large number of samples need to be observed one by one, the speed of switching samples is too slow, which not only has low efficiency but also leads to too long total observation time, and there may be adverse consequences for cells and biological samples. Content of the Utility Model

[0004] The purpose of the utility model is to provide an inverted microscope capable of quickly switching samples to solve the above problems.

[0005] The utility model realizes the above purpose through the following technical solutions:

[0006] An inverted microscope capable of quickly switching samples includes a microscope main body, a sliding groove arranged on the microscope main body, and a switching rack that slides in and out of the sliding groove. At least two groups of fixing units for fixing slides are arranged on the switching rack;

[0007] Among them, the fixing unit includes a sliding member that slides obliquely upward in the switching rack. The upper end of the sliding member is hinged with a pressing edge member, and the hinged position is located in the middle part of the pressing edge member. Among them, a sliding part is also slidably arranged inside the sliding member. The sliding part is hinged with the end of the pressing edge member through a first connecting rod. A first spring is also arranged between the sliding part and the sliding member. A driving structure for pushing and pulling the sliding part is also arranged in the switching rack and is hinged with the sliding part.

[0008] As a further optimized scheme of the utility model, the microscope main body further includes an eyepiece, an objective lens located below the switching rack, and a light source assembly suspended above the switching rack. The eyepiece, the objective lens, and the light source assembly are existing structures of an inverted microscope.

[0009] As a further optimized scheme of the utility model, a light-transmitting part is arranged on the switching rack for aligning and placing a slide for light-transmitting observation. The light-transmitting part can be made of optical glass or can be provided with a hollow.

[0010] As a further optimization solution of the present utility model, an upwardly inclined receiving groove is provided in the switching frame for the sliding member to slide. Wherein, a convex block is provided on the outer surface of the sliding member, and a corresponding rail groove is provided on the side wall of the receiving groove to limit the sliding direction and sliding amplitude of the sliding member. By the convex block and the rail groove, the sliding direction and sliding amplitude of the sliding member are restricted. When the sliding member reaches the highest point and the sliding part continues to slide, the pressing member will be pushed upward by the first connecting rod, so that the other side of the pressing member is pressed downward.

[0011] As a further optimization solution of the present utility model, telescopic grooves communicating with the receiving groove are provided on both sides of the switching frame. The driving structure includes a second connecting rod hinged on the surface of the sliding part and a sliding rod slidably arranged in the receiving groove. Wherein, the sliding rod is hinged to the end of the second connecting rod far from the sliding part, and a triangular slider is provided at the end of the sliding rod, which is used to push the sliding rod when the switching frame enters the sliding groove. A second spring for pushing the triangular slider outwards is also provided in the telescopic groove. This solution further sets a driving structure, which is automatically realized during the process of pushing the switching frame for switching, without the need for an electrically controlled driving structure or manual operation.

[0012] As a further optimization solution of the present utility model, a rubber pad is provided at the part where the pressing member contacts the glass slide, which has a certain buffering effect to prevent the glass slide from being broken.

[0013] As a further optimization solution of the present utility model, a gear position is provided on the sliding surface between the switching frame and the sliding groove, which is used to determine the position of the switching frame so that the glass slide is aligned with the objective lens. By setting the sliding gear position, it is easier for the switching frame to be aligned and positioned during the sliding process, without the need to actively observe the sliding amplitude of the switching frame.

[0014] The beneficial effects of the present utility model are as follows:

[0015] By setting an inclined lifting sliding member in the present utility model, when fixation is required, by pushing the sliding part and further pushing the sliding member obliquely upward by the first spring, the pressing member reaches the upper end of the edge of the glass slide. The sliding member has reached the highest point and does not move upward anymore, but when the sliding part continues to move upward, the first spring is compressed, and at the same time, the pressing member is pushed to rotate by the first connecting rod, so that one end of the pressing member is pressed downward to fix the glass slide. This fixing process can be realized by pushing the sliding part by the driving structure to first rise and then press downward. Conversely, when the glass slide is not fixed, the sliding member and the pressing member are retracted into the switching frame and will not form an obstruction to affect the replacement of the glass slide. When observing one glass slide, the other glass slide can be prepared in advance, greatly improving the observation efficiency. Description of the Drawings

[0016] Figure 1It is a schematic diagram of the overall structure of the present utility model.

[0017] Figure 2 is of the present utility model Figure 1 View A-A in it.

[0018] Figure 3 It is a schematic diagram of the switching frame and the fixing unit of the present utility model.

[0019] Figure 4 is of the present utility model Figure 3 Enlarged view of part B in it.

[0020] Figure 5 It is an external view of the sliding member and the edge pressing member of the present utility model.

[0021] In the figure: 1. Microscope main body; 11. Objective lens; 12. Light source assembly; 13. Slide groove; 2. Switching frame; 21. Telescopic groove; 22. Accommodating groove; 23. Light-transmitting part; 3. Fixing unit; 31. Sliding member; 32. Sliding part; 33. First spring; 34. Edge pressing member; 35. First connecting rod; 36. Second connecting rod; 37. Sliding rod; 38. Triangular slider; 39. Second spring; 310. Protrusion; 4. Slide glass. Specific embodiments

[0022] The following further describes the present application in detail with reference to the accompanying drawings. It is necessary to point out here that the following specific embodiments are only used to further illustrate the present application and cannot be understood as limiting the protection scope of the present application. Those skilled in the art can make some non-essential improvements and adjustments to the present application according to the above application content.

[0023] Embodiment 1

[0024] As Figures 1-5 shown, an inverted microscope capable of quickly switching samples includes a microscope main body 1, a slide groove 13 provided on the microscope main body 1, and a switching frame 2 that slides in and out of the slide groove 13. At least two groups of fixing units 3 for fixing the slide glass 4 are provided on the switching frame 2;

[0025] Among them, the fixing unit 3 includes a sliding member 31 that slides obliquely upward in the switching frame 2. The upper end of the sliding member 31 is hinged with an edge pressing member 34, and the hinged position is located in the middle part of the edge pressing member 34. Among them, a sliding part 32 is also slidably provided inside the sliding member 31. The sliding part 32 is hinged with the end of the edge pressing member 34 through a first connecting rod 35. A first spring 33 is also provided between the sliding part 32 and the sliding member 31. A driving structure for pushing and pulling the sliding part 32 is also provided in the switching frame 2 and is hinged with the sliding part 32.

[0026] In this solution, by setting the sliding member 31 that tilts and lifts, when fixation is required, the sliding portion 32 is pushed, and further the first spring 33 is used to push the sliding member 31 to rise obliquely upward, so that the edge pressing member 34 reaches the upper end of the edge of the glass slide 4. When the sliding member 31 reaches the highest position and no longer moves upward, but the sliding portion 32 continues to move upward, the first spring 33 is compressed, and at the same time, the edge pressing member 34 is pushed to rotate through the first connecting rod 35, so that one end of the edge pressing member 34 presses downward to fix the glass slide 4. This fixation process can be realized by the driving structure pushing the sliding portion 32 to first rise and then press downward. Conversely, when the glass slide 4 is not fixed, the sliding member 31 and the edge pressing member 34 are retracted into the switching frame 2, and no occlusion will be formed to affect the replacement of the glass slide 4. When observing one glass slide 4, the other glass slide 4 can be prepared in advance, greatly improving the observation efficiency.

[0027] The microscope main body 1 further includes an eyepiece, an objective lens 11 located below the switching frame 2, and a light source assembly 12 suspended above the switching frame 2. The eyepiece, the objective lens 11, and the light source assembly 12 are existing structures of an inverted microscope. The switching frame 2 is provided with a light-transmitting portion 23 for aligning and placing the glass slide 4 for light-transmitting observation. The light-transmitting portion can be made of optical glass or can be provided with a hollow.

[0028] An inclined upward receiving groove 22 is provided in the switching frame 2 for the sliding member 31 to slide. Among them, a convex block 310 is provided on the outer surface of the sliding member 31, and a corresponding rail groove is provided on the side wall of the receiving groove 22 to limit the sliding direction and sliding amplitude of the sliding member 31. When the sliding member 31 reaches the highest point, if the sliding portion 32 continues to slide, the edge pressing member 34 will be pushed upward by the first connecting rod 35, so that the other side of the edge pressing member 34 presses downward.

[0029] The two sides of the switching frame 2 are provided with telescopic grooves 21 communicating with the receiving groove 22. The driving structure includes a second connecting rod 36 hinged on the surface of the sliding portion 32 and a sliding rod 37 slidably arranged in the receiving groove 22. Among them, the sliding rod 37 is hinged to the end of the second connecting rod 36 far from the sliding portion 32, and a triangular slider 38 is provided at the end of the sliding rod 37 for pushing the sliding rod 37 when the switching frame 2 enters the sliding groove 13. A second spring 39 for pushing the triangular slider 38 outwards is further provided in the telescopic groove 21. In this solution, a driving structure is further provided, which is automatically realized during the process of pushing the switching frame 2 to switch, without the need for an electrically controlled driving structure or manual operation. Both sides of the triangular slider 38 have bevel edges. When the switching frame 2 slides along the sliding groove 13, the triangular slider 38 enters the sliding groove 13 and is pushed inward, driving the sliding rod 37 to push the second connecting rod 36. Conversely, when the triangular slider 38 loses the restriction of the sliding groove 13, it is pushed out by the second spring 39.

[0030] A rubber pad is provided at the contact part between the edge pressing member 34 and the glass slide 4, which has a certain buffering effect to prevent the glass slide from being broken. A gear position (not shown in the figure) is provided on the sliding surface between the switching rack 2 and the sliding groove 13, which is used to determine the position of the switching rack 2 so that the glass slide 4 is aligned with the objective lens 11. By setting the sliding gear position, it is easier for the switching rack 2 to be aligned and positioned during sliding, without the need to actively observe the sliding amplitude of the switching rack 2.

[0031] The specific implementation method is as follows: When in use, taking Figure 2 a perspective view as an example (the orientation words used in this paragraph to describe up and down are only for Figure 2 this perspective view for the convenience of description, rather than the orientation in actual use), the glass slide 4 below is in a pressed state and is being observed. Since the triangular slider 38 above is not pressed in, the sliding member 31 is in a retracted state. Another operator replaces the glass slide 4 above. When the observation of the glass slide 4 below is completed, the switching rack 2 is pushed downward, then the triangular slider 38 above is pressed back, and the corresponding fixing unit 3 fixes the glass slide 4, while the triangular slider 38 below extends, and the corresponding fixing unit 3 retracts into the switching rack 2. The fixing is automatically released during the switching process, and another glass slide 4 can be prepared while observing one glass slide 4 to improve the observation efficiency.

[0032] The above embodiments only represent several implementation modes of the present invention. The description is relatively specific and detailed, but it should not be construed as a limitation on the scope of the patent of the present invention. It should be noted that for those of ordinary skill in the art, without departing from the concept of the present invention, several modifications and improvements can still be made, and these all belong to the protection scope of the present invention.

Claims

1. An inverted microscope capable of rapidly switching samples, characterized in that: The invention comprises a microscope body (1), a slide groove (13) arranged on the microscope body (1), and a switching frame (2) that slides in and out of the slide groove (13), wherein the switching frame (2) is provided with at least two groups of fixing units (3) for fixing a slide glass (4); The fixing unit (3) comprises a sliding member (31) which is arranged in the switching frame (2) and slides obliquely upward. The upper end of the sliding member (31) is hingedly provided with a pressure member (34), and the hinge position is located at the middle part of the pressure member (34). A sliding part (32) is also slidably provided inside the sliding member (31). The sliding part (32) is hinged to the end of the pressure member (34) through a first connecting rod (35). A first spring (33) is also arranged between the sliding part (32) and the sliding member (31). A driving structure which is hinged to the sliding part (32) to push and pull the sliding part (32) is also arranged in the switching frame (2).

2. An inverted microscope capable of rapidly switching samples according to claim 1, characterized in that: The microscope body (1) also comprises an eyepiece, an objective lens (11) located below the switching frame (2), and a light source assembly (12) suspended above the switching frame (2).

3. The inverted microscope capable of rapidly switching samples according to claim 1, characterized in that: The switching frame (2) is provided with a light-transmitting portion (23) for aligning and placing a glass slide (4) for light-transmitting observation.

4. The inverted microscope capable of rapidly switching samples according to claim 1, characterized in that: The switching frame (2) is provided with an upwardly inclined receiving groove (22) for the sliding member (31) to slide, wherein a protrusion (310) is provided on the outer surface of the sliding member (31), and a corresponding rail groove is provided on the side wall of the receiving groove (22) to limit the sliding direction and sliding amplitude of the sliding member (31).

5. The inverted microscope capable of rapidly switching samples according to claim 4, characterized in that: Telescopic grooves (21) connected to the accommodating groove (22) are provided on both sides of the switching frame (2); the driving structure includes a second connecting rod (36) hinged on the surface of the sliding portion (32), and a sliding rod (37) slidably arranged in the accommodating groove (22); wherein the sliding rod (37) is hinged on the end of the second connecting rod (36) away from the sliding portion (32); a triangular sliding block (38) is provided at the end of the sliding rod (37) for pushing the sliding rod (37) when the switching frame (2) enters the sliding groove (13); and a second spring (39) for pushing the triangular sliding block (38) outward is also provided in the telescopic groove (21).

6. The inverted microscope capable of rapidly switching samples according to claim 5, characterized in that: A rubber pad is provided at the position where the edge pressing piece (34) contacts the glass slide (4).

7. The inverted microscope capable of rapidly switching samples according to claim 1, characterized in that: The sliding surface between the switching frame (2) and the sliding groove (13) is provided with a gear position for determining the position of the switching frame (2) so that the slide glass (4) is aligned with the objective lens (11).