Sample analyzer
By designing a heat dissipation module in the sample analyzer that is in direct contact with the excitation light source, the temperature of the excitation light source is maintained stable, and the problem of reducing detection accuracy caused by fluctuations in the excitation beam intensity is solved, and the purpose of improving detection accuracy is achieved.
Patent Information
- Application Number
- CN202421263714.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-04
- Publication Date
- 2025-06-03
- Estimated Expiration
- 2034-06-04
AI Technical Summary
In PCR detection, fluctuations in the intensity of the excitation beam will affect the generation of fluorescence signals, resulting in abnormalities in the detection results and a decrease in accuracy.
Design a sample analyzer, including an optical detection module and a heat dissipation module, which is in direct contact with the excitation light source, and keeps the temperature of the excitation light source stable through the cooling liquid circulation and fan heat dissipation.
By keeping the temperature of the excitation light source stable, the fluctuations in the excitation beam intensity are reduced, the stability of the fluorescence signal is improved, and the accuracy of detection is improved.
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Figure CN222938965U_ABST
Abstract
Description
Technical Field
[0001] This application relates to the technical field of medical devices, and particularly to a sample analyzer. Background Art
[0002] Nucleic acid detection is a commonly used molecular biology technique, which is currently widely used in fields such as clinical diagnosis, agricultural monitoring, and food safety. Especially when large-scale infectious diseases occur, nucleic acid detection can be used as the gold standard for disease diagnosis.
[0003] Currently, the commonly used nucleic acid detection method is PCR detection. The general principle of PCR (Polymerase Chain Reaction) detection is a process in which, under the catalysis of DNA polymerase, using the mother strand DNA as a template and a specific primer as the extension starting point, daughter strand DNA complementary to the mother strand DNA is replicated in vitro. PCR detection can be used to detect and diagnose the presence and quantity of pathogens or specific gene sequences.
[0004] In PCR detection, the excitation light beam emitted by the excitation light source in the optical detection module is irradiated into the reaction vessel, so that the reaction mixture inside the reaction vessel emits a fluorescence signal, and then the sample is detected and judged through the fluorescence signal.
[0005] The fluctuation of the excitation light beam intensity will affect the generation of the fluorescence signal, thereby causing the result of obtaining the fluorescence signal to be in an abnormal state and reducing the detection accuracy. Therefore, how to maintain the stability of the excitation light beam intensity is crucial for improving the detection accuracy. Summary of the Utility Model
[0006] Based on this, it is necessary to provide a sample analyzer that can reduce fluctuations and maintain the stability of the excitation light beam intensity in view of the above problems.
[0007] A sample analyzer, the sample analyzer has a detection station, and the sample analyzer includes:
[0008] An optical detection module, including an excitation light source, the excitation light source is used to emit an excitation light beam into the reaction vessel located at the detection station, and the excitation light beam can excite the reaction mixture in the reaction vessel to emit a fluorescence signal;
[0009] A heat dissipation module, which is in direct contact with the excitation light source and is used to dissipate heat from the excitation light source.
[0010] In some of these embodiments, the heat dissipation module includes a liquid storage member, a power pump, a cooling member, a heat dissipation member, and a blower. The liquid storage member, the power pump, the cooling member, and the heat dissipation member are sequentially connected and form a flow channel for the coolant to circulate. The cooling member is in direct contact with the excitation light source and is used to dissipate heat from the excitation light source. The blower is installed on the heat dissipation member and is used to blow air to the heat dissipation member and dissipate heat.
[0011] In some of these embodiments, the heat dissipation member is a cold plate.
[0012] In some of these embodiments, the sample analyzer includes a detection station group, and the detection station group has a plurality of the detection stations;
[0013] There are a plurality of the optical detection modules, the cooling members, and the detection station groups, and all the detection station groups and all the cooling members correspond to all the optical detection modules one by one; all the cooling members are connected in parallel between the power pump and the liquid storage member.
[0014] In some of these embodiments, the heat dissipation module further includes a temperature detection member, and the temperature detection member is arranged on one of the cooling members and is used to detect the actual temperature of the cooling member where it is located;
[0015] The optical detection module further includes a controller. Both the blower and the temperature detection member are electrically connected to the controller, and the controller is used to control the blower to increase the rotation speed when the actual temperature is equal to or greater than a set temperature threshold.
[0016] In some of these embodiments, the cooling member is arranged on one side of the excitation light source and is in surface contact with the excitation light source.
[0017] In some of these embodiments, the heat dissipation module further includes a thermal conductive coating coated on the surface of at least one of the excitation light source and the cooling member in contact with the other.
[0018] In some of these embodiments, the heat dissipation module further includes a connecting member, and the excitation light source and the cooling member are detachably connected to the cooling member through the connecting member.
[0019] In some of these embodiments, the excitation light source and the cooling member are screwed to the cooling member through the connecting member.
[0020] In some of these embodiments, there are a plurality of the connecting members, and all the connecting members are arranged circumferentially around the excitation light source, or all the connecting members are distributed on opposite sides of the excitation light source.
[0021] The above sample analyzer is designed such that the heat dissipation module is in direct contact with the excitation light source and is used to dissipate heat from the excitation light source, which can maintain the temperature stability during the operation of the excitation light source. As a result, it is beneficial to reduce the intensity fluctuation of the excitation light beam emitted by the excitation light source and maintain the stability of the intensity of the excitation light beam. In this case, the reaction mixture inside the reaction vessel can be stably excited to emit fluorescence signals, ultimately achieving the purpose of improving the detection accuracy. Description of the Drawings
[0022] Figure 1 It is a schematic structural diagram of the connection between the excitation light source and the cooling component in the sample analyzer according to an embodiment of the present application.
[0023] Figure 2 It is a schematic structural diagram of the heat dissipation module in the sample analyzer according to an embodiment of the present application.
[0024] Figure 3 It is a schematic structural diagram of the cooperation between the heat dissipation component and the fan in the heat dissipation module of the sample analyzer according to an embodiment of the present application.
[0025] Figure 4 is Figure 3 A schematic structural diagram of another perspective after the cooperation between the heat dissipation component and the fan shown.
[0026] Reference Numerals in the Drawings:
[0027] 1. Sample Analyzer;
[0028] 10. Optical Detection Module; 20. Heat Dissipation Module;
[0029] 11. Excitation Light Source;
[0030] 21. Liquid Storage Component; 22. Power Pump; 23. Cooling Component; 24. Heat Dissipation Component; 25. Connecting Component; 26. Fan. Detailed Embodiments
[0031] To make the above objects, features, and advantages of the present application more apparent and understandable, the following detailed description of the specific embodiments of the present application is provided in conjunction with the accompanying drawings. Many specific details are set forth in the following description to facilitate a thorough understanding of the present application. However, the present application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without departing from the connotation of the present application. Therefore, the present application is not limited by the specific embodiments disclosed below.
[0032] In the description of the present application, it should be understood that the orientation or positional relationship indicated by the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation to the present application.
[0033] In addition, the terms "first" and "second" are only used for descriptive purposes and should not be construed as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include at least one of such features. In the description of the present application, the meaning of "a plurality of" is at least two, such as two, three, etc., unless otherwise specifically and clearly defined.
[0034] In the present application, unless otherwise clearly defined and limited, the terms such as "mounted", "connected", "connected to", "fixed" should be understood in a broad sense. For example, it may be a fixed connection, a detachable connection, or integrated; it may be a mechanical connection or an electrical connection; it may be directly connected or indirectly connected through an intermediate medium, and it may be the communication inside two elements or the interaction relationship between two elements, unless otherwise clearly limited. For those of ordinary skill in the art, the specific meanings of the above terms in the present application can be understood according to specific circumstances.
[0035] In the present application, unless otherwise clearly defined and limited, the first feature being "on" or "under" the second feature may be that the first and second features are in direct contact, or the first and second features are indirectly in contact through an intermediate medium. Moreover, the first feature being "above", "over" and "on top of" the second feature may be that the first feature is directly above or obliquely above the second feature, or merely indicates that the first feature has a higher horizontal height than the second feature. The first feature being "under", "beneath" and "underneath" the second feature may be that the first feature is directly below or obliquely below the second feature, or merely indicates that the first feature has a lower horizontal height than the second feature.
[0036] It should be noted that when an element is referred to as "fixed to" or "disposed on" another element, it can be directly on the other element or there may also be an intermediate element. When an element is considered to be "connected" to another element, it can be directly connected to the other element or there may be an intermediate element at the same time. The terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used in this article are only for illustrative purposes and do not represent the only implementation.
[0037] Nucleic acid detection is a commonly used molecular biology technique, which is currently widely used in clinical diagnosis, agricultural monitoring, food safety and other fields. Especially when large-scale infectious diseases occur, nucleic acid detection can be used as the gold standard for disease diagnosis.
[0038] Please refer to Figure 1 , the commonly used nucleic acid detection method is PCR detection. In PCR detection, the excitation beam emitted by the excitation light source 11 irradiates the reaction vessel located at the detection station, causing the reaction mixture inside the reaction vessel to emit a fluorescence signal. Then, the optical detection module 10 detects and judges the sample through the fluorescence signal.
[0039] During the actual detection process, the intensity of the excitation beam is prone to fluctuate, which will affect the generation of the fluorescence signal, resulting in an abnormal state in the result of obtaining the fluorescence signal and reducing the detection accuracy.
[0040] The applicant found through careful research that one of the reasons affecting the intensity fluctuation of the excitation beam is the temperature of the excitation light source 11. Specifically, the intensity of the excitation beam is easily affected by the temperature of the excitation light source 11. When the temperature of the excitation light source 11 fluctuates, it will affect the stability of the excitation light source 11 to emit light, resulting in the intensity fluctuation of the excitation light source 11, and then affecting the generation of the fluorescence signal.
[0041] Please refer to again Figure 1 and at the same time refer to Figure 2, in order to alleviate the problems caused by the intensity fluctuation of the excitation light source 11 due to temperature fluctuation, the applicant has designed a sample analyzer 1 through in-depth research. The sample analyzer 1 is used for nucleic acid detection. Among them, the sample analyzer 1 has a detection station, and the sample analyzer 1 includes an optical detection module 10 and a heat dissipation module 20. The optical detection module 10 includes an excitation light source 11, a receiver, and a controller. The excitation light source 11 and the receiver are both electrically connected to the controller. The excitation light source 11 is used to emit an excitation beam into the reaction vessel located at the detection station. The excitation beam can excite the reaction mixture in the reaction vessel to emit a fluorescence signal. The receiver is used to receive the fluorescence signal and feedback it to the controller. The controller makes a judgment on the detection result according to the strength of the fluorescence signal fed back by the receiver. The heat dissipation module 20 is in direct contact with the excitation light source 11 and is used to dissipate heat from the excitation light source 11.
[0042] Specifically, during the operation of the excitation light source 11, heat will be released. If the heat cannot be dissipated in time, it will cause heat accumulation and temperature fluctuation of the excitation light source 11. Therefore, in this application, by designing the heat dissipation module 20 to be in direct contact with the excitation light source 11 and used to dissipate heat from the excitation light source 11, the temperature stability during the operation of the excitation light source 11 can be maintained, which is beneficial to reducing the intensity fluctuation of the excitation beam emitted by the excitation light source 11 and maintaining the stability of the intensity of the excitation beam. In this case, the reaction mixture inside the reaction vessel can be stably excited to emit a fluorescence signal, and finally the purpose of improving the detection accuracy is achieved.
[0043] Combined with Figure 1 and Figure 2 , and referring to Figure 3 and Figure 4 , in some optional embodiments of this application, the heat dissipation module 20 includes a liquid storage member 21, a power pump 22, a cooling member 23, a heat dissipation member 24, and a fan 26. The liquid storage member 21, the power pump 22, the cooling member 23, and the heat dissipation member 24 are sequentially connected and form a flow channel for the coolant to circulate. The power pump 22 is used to drive the coolant to circulate between the cooling member 23, the heat dissipation member 24, and the liquid storage member 21. The cooling member 23 is in direct contact with the excitation light source 11 and is used to dissipate heat from the excitation light source 11. The fan 26 is installed on the heat dissipation member 24 and is used to blow air to the heat dissipation member 24 and dissipate heat.
[0044] The liquid storage member 21 has a hollow structure, such as a liquid storage barrel. The liquid storage member 21 is used to store the coolant, such as water, alcohol, etc. For example, water is used. Water is convenient to obtain as a coolant, has a low price, and is convenient for reducing costs.
[0045] The cooling member 23 is in direct contact with the excitation light source 11, and a cooling flow channel for the coolant to flow through is provided inside the cooling member 23. The cooling member 23 is in contact with the excitation light source 11, so that the heat of the excitation light source 11 can be transferred to the coolant inside the cooling member 23 through the cooling member 23 and absorbed by the coolant. Then, during the process of the coolant circulating and flowing, the heat is carried away by the coolant to achieve heat dissipation of the excitation light source 11.
[0046] As an example, the cooling member 23 can be a water-cooling block.
[0047] A heat dissipation flow channel for the coolant to flow through is provided inside the heat dissipation member 24. The heat dissipation member 24 has a relatively large contact surface with the outside. During the process of the coolant flowing through the heat dissipation flow channel, under the action of the fan 26, the heat absorbed by the coolant is quickly diffused to the outside through the contact surface between the heat dissipation member 24 and the outside to achieve heat dissipation of the coolant.
[0048] As an example, the heat dissipation member 24 is a radiator. There is a relatively large contact area between the radiator and the outside, so that the coolant can achieve rapid heat dissipation when passing through the radiator.
[0049] Specifically, the heat dissipation principle of the cooperation between the radiator and the fan 26 is as follows: The radiator includes a plurality of flat pipes arranged in parallel, and wavy heat dissipation fins are welded between every two adjacent flat pipes. During the process of the coolant flowing through each flat pipe, the heat of the coolant will be transferred to the heat dissipation fins adjacent to and connected to the flat pipe through the flat pipe. Under the blowing action of the fan 26, the heat of the flat pipe and the heat dissipation fins can be quickly diffused to the outside and dissipate heat.
[0050] The power pump 22 is used to drive the coolant to circulate between the cooling member 23, the heat dissipation member 24 and the liquid storage member 21 to achieve heat dissipation of the excitation light source 11 and can recycle the coolant.
[0051] During actual operation, the coolant in the liquid storage member 21 flows out under the action of the power pump 22, and successively flows through the cooling flow channel of the cooling member 23 and the heat dissipation flow channel of the heat dissipation member 24 and then returns to the liquid storage member 21. During the process of the coolant flowing through the cooling flow channel, since the temperature of the coolant is lower than that of the excitation light source 11, the heat of the excitation light source 11 can be transferred to the coolant through the cooling member 23 and carried away by the coolant to achieve heat dissipation of the excitation light source 11. The coolant absorbs the heat of the excitation light source 11 and the temperature rises. During the process of flowing through the heat dissipation flow channel of the heat dissipation member 24, under the action of the fan 26, the heat is diffused to the outside through the contact surface between the heat dissipation member 24 and the outside to achieve cooling of the coolant. Then, the cooled coolant returns to the liquid storage member 21 and undergoes the next cycle.
[0052] It can be seen that by designing the liquid storage member 21, the power pump 22, the cooling member 23, the heat dissipation member 24 and the fan 26, the coolant can flow within the circulation path formed by the liquid storage member 21, the power pump 22, the cooling member 23 and the heat dissipation member 24, and can repeatedly dissipate heat from the excitation light source 11, with good heat dissipation effect.
[0053] In some alternative embodiments of the present application, the sample analyzer 1 includes a detection station group having a plurality of detection stations; there are a plurality of optical detection modules 10, cooling members 23 and detection station groups, and all the detection station groups and all the cooling members 23 correspond to all the optical detection modules 10 one by one; all the cooling members 23 are connected in parallel between the power pump 22 and the liquid storage member 21.
[0054] The excitation light sources 11 of each optical detection module 10 respectively emit excitation beams to all the detection stations of the detection station group corresponding to it, and a reaction vessel is provided at each detection station. In this way, the sample analyzer 1 can simultaneously detect the reaction vessels at the detection stations of multiple detection station groups, with high detection efficiency. Each cooling member 23 respectively dissipates heat from the excitation light source 11 of the optical detection module 10 corresponding to it.
[0055] By designing that there are a plurality of optical detection modules 10 and cooling members 23, and all the cooling members 23 cooperate, heat dissipation and temperature control can be performed on the excitation light sources 11 of all the optical detection modules 10, with a better temperature control effect. And compared with setting a plurality of heat dissipation modules 20 to perform temperature control on the excitation light sources 11 of a plurality of optical detection modules 10 one by one, only by setting one heat dissipation module 20, temperature control of the excitation light sources 11 of a plurality of optical detection modules 10 can be achieved, which simplifies the structure and occupies less space.
[0056] Next, taking the case where there are three optical detection modules 10, cooling members 23 and detection station groups respectively, the heat dissipation process of the heat dissipation component will be described in detail.
[0057] Among them, the liquid storage barrel, the power pump 22 and the heat dissipation member 24 are all located on the main path through which the coolant flows, and the three cooling members 23 respectively form three branches through which the coolant flows. The coolant flowing out of the power pump 22 is branched into three branches on the main path, flows through the three branches and then returns to the main path, and then flows through the heat dissipation member 24 and the liquid storage member 21 in sequence and then reflows into the power pump 22.
[0058] Among them, the coolant is output from the liquid storage member 21, and the path of flowing through one of the branches and then returning to the liquid storage member 21 is as shown by the arrow x→a→b→c→d→e→f→u→v→w. The coolant is output from the power pump 22, and the path of flowing through the other branch and then returning to the power pump 22 is as shown by the arrow x→a→b→g→h→i→j→k→t→u→v→w. The coolant is output from the power pump 22, and the path of flowing through the last branch and then returning to the power pump 22 is as shown by the arrow x→a→b→g→m→n→p→q→r→s→t→u→v→w.
[0059] In some alternative embodiments of the present application, the heat dissipation module 20 further includes a temperature detection member, which is disposed on one of the cooling members 23 and is used to detect the actual temperature of the cooling member 23 where it is located; both the fan 26 and the temperature detection member are electrically connected to the controller of the optical detection module 10, and the controller is used to control the fan 26 to increase the rotation speed when the actual temperature is equal to or greater than the set temperature threshold.
[0060] During the actual working process, all the excitation light sources 11 of the optical detection module 10 are started synchronously, and each cooling member 23 dissipates heat from the excitation light source 11 corresponding to it synchronously. Therefore, the heat dissipation conditions of each cooling member 23 are roughly the same. Therefore, by designing a temperature detection member disposed on one of the cooling members 23 and used to detect the actual temperature of the cooling member 23 where it is located, the approximate heat dissipation conditions of all the cooling members 23 can be known, and the controller can adjust the output power of the fan 26 according to this situation.
[0061] It can be understood that when the actual temperature of the cooling member 23 is equal to or greater than the set temperature threshold, it indicates that the heat dissipation effect of the cooling member 23 is not good. At this time, the controller controls the fan 26 to increase the output power to increase the heat exchange between the coolant flowing through the heat dissipation member 24 and the outside world, and then form a coolant with a further reduced temperature. When the coolant with a lower temperature flows through the cooling member 23, it can absorb more heat and the temperature will not rise too high, having a better heat dissipation effect.
[0062] When the actual temperature of the cooling member 23 is less than the set temperature threshold, it indicates that the heat dissipation effect of the cooling member 23 is relatively good. At this time, the controller controls the fan 26 to maintain the current output power, and the excitation light source 11 can be effectively cooled. In this case, both a better heat dissipation effect can be ensured and the energy consumption can be reduced.
[0063] Please refer to again Figure 1, in some alternative embodiments of the present application, the cooling member 23 is disposed on one side of the excitation light source 11 and is in surface contact with the excitation light source 11. The design of disposing the cooling member 23 on one side of the excitation light source 11 facilitates the installation of both the cooling member 23 and the excitation light source 11. Compared with the way that the cooling member 23 and the excitation light source 11 are in point contact or line contact, the design of the cooling member 23 being in surface contact with the excitation light source 11 has a larger contact area, and the heat on the excitation light source 11 can be quickly and largely directly transferred to the cooling member 23 through the contact surface between the two, resulting in good heat dissipation effect.
[0064] In some alternative embodiments of the present application, the heat dissipation module 20 further includes a thermal conductive coating coated on the surface of at least one of the excitation light source 11 and the cooling member 23 in contact with the other.
[0065] For example, the thermal conductive coating is coated on the excitation light source 11 and is located on the surface of the excitation light source 11 in contact with the cooling member 23, or the thermal conductive coating is coated on the cooling member 23 and is located on the surface of the cooling member 23 in contact with the excitation light source 11, or the thermal conductive coating can also be coated on both the excitation light source 11 and the cooling member 23 and is located on the surface where the excitation light source 11 and the cooling member 23 are in contact with each other.
[0066] The thermal conductive coating has a high thermal conductivity coefficient, which can quickly transfer the heat on the excitation light source 11 to the cooling member 23 to improve the heat conduction speed and has good heat conduction effect, thereby further optimizing the heat dissipation effect.
[0067] In some alternative embodiments of the present application, the heat dissipation module 20 further includes a connecting member 25, and the excitation light source 11 and the cooling member 23 are detachably connected to the cooling member 23 through the connecting member 25.
[0068] For example, the connecting member 25 can be a pin shaft, a screw or other structures, which can be specifically set according to requirements.
[0069] By providing the connecting member 25 to detachably connect the excitation light source 11 and the heat dissipation member 24, on the one hand, the simplicity of assembly and disassembly of both the excitation light source 11 and the heat dissipation member 24 can be improved. On the other hand, when the excitation light source 11 and the heat dissipation member 24 are assembled and connected through the connecting member 25, the reliability of the contact between the excitation light source 11 and the cooling member 23 is ensured, so that the heat on the excitation light source 11 can be stably transferred to the cooling member 23.
[0070] In some alternative embodiments of the present application, the excitation light source 11 and the cooling member 23 are screwed to the cooling member 23 through the connecting member 25. That is to say, the connecting member 25 is a connecting component with a thread such as a screw or a bolt. By providing the connecting member 25 as a connecting component with a thread, it is beneficial to improve the simplicity of the connection between the excitation light source 11 and the cooling member 23.
[0071] In some alternative embodiments of the present application, there are multiple connecting members 25, and all the connecting members 25 are arranged circumferentially around the excitation light source 11. Alternatively, all the connecting members 25 are distributed on two opposite sides of the excitation light source 11, and all the connecting members 25 are used to connect the excitation light source 11 and the cooling member 23. By providing multiple connecting members 25, the connection strength between the excitation light source 11 and the cooling member 23 is enhanced to a certain extent, making the contact between the excitation light source 11 and the cooling member 23 closer and more reliable.
[0072] For the above sample analyzer 1, by designing the heat dissipation module 20 to be in direct contact with the excitation light source 11 and used for dissipating heat from the excitation light source 11, the temperature stability during the operation of the excitation light source 11 can be maintained. Thereby, it is beneficial to reduce the intensity fluctuation of the excitation beam emitted by the excitation light source 11 and maintain the intensity stability of the excitation beam. In this case, the reaction mixture inside the reaction vessel can be stably excited to emit fluorescence signals, ultimately achieving the purpose of improving the detection accuracy.
[0073] The technical features of the above-described embodiments can be combined arbitrarily. For the sake of brevity of description, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, it should be considered as within the scope described in this specification.
[0074] The above-described embodiments only represent several implementation manners of the present application. The description is relatively specific and detailed, but it should not be construed as a limitation on the scope of the patent application. It should be noted that for those of ordinary skill in the art, without departing from the concept of the present application, several modifications and improvements can still be made, and these all belong to the protection scope of the present application. Therefore, the protection scope of the patent of the present application shall be subject to the appended claims.
Claims
1. A sample analyzer, characterized in that: The sample analyzer has a detection station, and the sample analyzer includes: An optical detection module (10) comprises an excitation light source (11), wherein the excitation light source (11) is used to emit an excitation light beam into a reaction container located at the detection station, wherein the excitation light beam can excite a reaction mixture in the reaction container to emit a fluorescent signal; A heat dissipation module (20), comprising a cooling element (23), wherein the cooling element (23) is in direct contact with the excitation light source (11) and is used to dissipate heat from the excitation light source (11); Wherein, the cooling element (23) has a cooling channel for the flow of cooling liquid.
2. The sample analyzer according to claim 1, characterized in that: The heat dissipation module (20) comprises a liquid storage component (21), a power pump (22), a heat dissipation component (24) and a fan (26); the liquid storage component (21), the power pump (22), the cooling component (23) and the heat dissipation component (24) are sequentially connected to form a flow channel for circulating coolant; the fan (26) is installed on the heat dissipation component (24) and is used to blow air to the heat dissipation component (24) and dissipate heat.
3. The sample analyzer according to claim 2, characterized in that: The heat sink (24) is a cold row.
4. The sample analyzer according to claim 2, characterized in that: The sample analyzer comprises a detection station group, and the detection station group has a plurality of detection stations; The optical detection module (10), the cooling element (23) and the detection station group are all multiple, and all the detection station groups and all the cooling elements (23) correspond one-to-one to all the optical detection modules (10); all the cooling elements (23) are connected in parallel between the power pump (22) and the liquid storage element (21).
5. The sample analyzer according to claim 4, characterized in that: The heat dissipation module (20) further comprises a temperature detection element, which is arranged on one of the cooling elements (23) and is used to detect the actual temperature of the cooling element (23) on which it is located; The optical detection module (10) also includes a controller, the fan (26) and the temperature detection element are both electrically connected to the controller, and the controller is used to control the fan (26) to increase the rotation speed when the actual temperature is equal to or greater than a set temperature threshold.
6. The sample analyzer according to claim 2, characterized in that: The cooling element (23) is arranged on one side of the excitation light source (11) and is in surface contact with the excitation light source (11).
7. The sample analyzer according to claim 6, characterized in that: The heat dissipation module (20) further comprises a heat conductive coating coated on a surface of at least one of the excitation light source (11) and the cooling element (23) that contacts the other.
8. The sample analyzer according to claim 2, characterized in that: The heat dissipation module (20) further comprises a connecting member (25), and the excitation light source (11) and the cooling member (23) are detachably connected to the cooling member (23) via the connecting member (25).
9. The sample analyzer according to claim 8, characterized in that: The excitation light source (11) and the cooling member (23) are screwed to the cooling member (23) via the connecting member (25).
10. The sample analyzer according to claim 8, characterized in that: There are a plurality of connecting members (25), and all of the connecting members (25) are arranged around the circumference of the excitation light source (11), or all of the connecting members (25) are distributed on two opposite sides of the excitation light source (11).