Oral mucosa cell sampling tool
By designing an oral mucosal cell material extraction tool including outer sleeves, restraint rods and multiple extraction parts, the problem of easy mixing of samples during sampling is solved, and the precise distinction and efficient preservation of samples are achieved.
Patent Information
- Application Number
- CN202520713794.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-04-16
- Publication Date
- 2025-06-06
- Estimated Expiration
- 2035-04-16
AI Technical Summary
During the oral mucosal cell sampling process, due to the large number of materials, the mucosal cell samples on each cotton swab are prone to mix up, making it difficult to distinguish the oral part of each sample during the preservation process, affecting cell culture and disease detection in the pathology department.
A oral mucosal cell material extraction tool is designed, including outer sleeves, restraint rods and multiple material extraction parts. Each material extraction part consists of a material extraction part and a push rod. Through the cooperation of the slide chute and the limiting groove, the precise control and distinction of the material extraction part can be achieved.
Through this tool, medical staff can clearly distinguish the oral parts corresponding to each material, avoid mixing mucosal cell samples, and improve the sample preservation and detection efficiency.
Smart Images
Figure CN222942366U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of oral sampling instruments, and in particular relates to an oral mucosal cell sampling tool. Background Art
[0002] At present, the gold standard for clinical diagnosis of oral cancer or OPMD is histopathological examination, but biopsy is traumatic and subjective, and its clinical application has certain limitations. Therefore, oral mucosal liquid-based thin layer cytology is of great significance for early clinical diagnosis. Oral mucosal liquid-based thin layer cytology (TCT) is a technology that preserves exfoliated cells in liquid and uses special equipment to evenly disperse the cells and attach them to a glass slide to make a smear. Through the principles of mechanical, pneumatic and fluid mechanics, the cells are smeared into a uniform thin layer specimen using fully automatic equipment.
[0003] In obtaining oral mucosal cells, currently in clinical practice, doctors usually use multiple cotton swabs to scrape the mucosa of various parts of the patient's mouth, such as the inner side of the left and right cheeks, hard palate, etc., and then mix the cotton swabs with mucosal cells in a protective solution to obtain mucosal cell samples from various parts of the patient's mouth. However, during the sampling process, due to the large number of sampling sites, the mucosal cell samples on each cotton swab are prone to confusion, resulting in medical staff not being clear about the oral site corresponding to each mucosal cell sample during the storage process, which makes it inconvenient for the pathology department to perform cell culture doubling to detect disease genes.
[0004] In view of the above problems, the utility model provides a tool for collecting oral mucosal cells. Utility Model Content
[0005] In order to overcome the problems raised in the background technology, the utility model adopts the following technical solutions: an oral mucosal cell sampling tool, comprising: an outer sleeve, the outer sleeve having a first end and a second end, wherein a accommodating cavity is opened from the first end to the second end; a constraint rod, arranged in the accommodating cavity, wherein a plurality of slide grooves are opened on the outer surface of the constraint rod; a plurality of sampling members, each of the sampling members comprising: a sampling portion and a pushing rod, the sampling portion is arranged at one end of the pushing rod, wherein the pushing rod is arranged in the slide groove, the sampling portion is located outside the accommodating cavity, and when the pushing rod moves relative to the constraint rod along the slide groove toward the first end, the sampling portion moves away from the first end of the outer sleeve.
[0006] In some embodiments of the present application, a receiving piece is further included, which is configured at the first end of the outer sleeve, and the receiving piece has a chamber, which is communicated with the accommodating chamber, wherein the material collecting portion is located in the chamber, and when the pushing rod moves along the sliding groove toward the first end relative to the restraining rod, the material collecting portion extends out from the chamber.
[0007] In some embodiments of the present application, a plurality of limiting grooves are opened from the outer wall of the outer sleeve toward the accommodating cavity, wherein each limiting groove corresponds to a sliding groove, and the push rod portion extends out from the limiting groove.
[0008] Furthermore, a plurality of the limiting grooves are distributed in a circular array on the outer wall of the outer sleeve.
[0009] Furthermore, the pushing rod includes: a connecting end and a pushing end, wherein the connecting end extends from the accommodating cavity, the material collecting portion is connected to the connecting end, the pushing end extends from the limiting groove, and the pushing end can move linearly in the limiting groove toward the first end and the second end, so that the material collecting portion moves away from the first end and approaches the first end.
[0010] Furthermore, a breaking line is arranged around the outer wall of the pushing rod, wherein the breaking line is closer to the connecting end than to the pushing end.
[0011] Furthermore, the outer wall of each of the push rods also has an identification groove, wherein the cross-sectional shape of each of the identification grooves is different.
[0012] In some embodiments of the present application, the sampling portion includes: a connecting piece, which is connected to the connecting end; and a sampling piece, which is used to collect oral mucosal cells, wherein the sampling piece is connected to the connecting piece.
[0013] Furthermore, the sampling component includes: a water-soluble shell and a sponge, wherein the water-soluble shell is bonded to the connecting component, and the sponge is arranged in the water-soluble shell.
[0014] Beneficial effects of the utility model:
[0015] 1. By setting an outer sleeve, a restraining rod and a plurality of sampling pieces, when in use, for example, to sample mucosal cells on the right side of the patient's oral cavity (inner side of the right cheek), the push rod is driven to move relative to the restraining rod along the slide groove toward the first end. At this time, the sampling portion is away from the first end of the outer sleeve, and is then used by medical personnel to collect samples. Then, the sampling portion with mucosal cells obtained from the right side of the patient's oral cavity is placed in a corresponding storage container for storage. Then, the remaining sampling pieces are used to sample other parts of the patient's oral cavity in turn, and the samples are placed in corresponding storage containers. This makes it easy for medical personnel to distinguish the oral mucosal cells corresponding to each sampling piece, thereby avoiding the problem of confusion among mucosal cell samples.
[0016] 2. By setting a breaking line on the outer wall of the pushing rod, when in use, after the sampling is completed, the sampling part of the sampling piece can be immediately separated from the pushing rod and placed in a corresponding storage container. Under this setting, it is beneficial for medical personnel to distinguish oral mucosal cells in time and avoid contamination of oral mucosal cell samples. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] Figure 1 The overall structural diagram of the name of the utility model;
[0018] Figure 2 A schematic diagram of the structure of the material-drawing part for the name of the utility model;
[0019] Figure 3 A schematic diagram of the structure of the material taking part and the restraining rod of the utility model;
[0020] Figure 4 A schematic cross-sectional view of the outer sleeve of the utility model;
[0021] Figure 5 A schematic diagram of the structure of the material-taking part of the name of the utility model;
[0022] Figure 6 A schematic diagram of the push rod structure of the utility model;
[0023] Figure 7 A schematic diagram of the structure of the sampling piece of the name of the utility model;
[0024] Figure 8 A schematic cross-sectional view of a sampling piece for the name of the utility model;
[0025] Fig. 9 A schematic diagram of the main structure of the container with the name of the utility model;
[0026] In the figure, 1, outer sleeve; 11, limit groove; 12, receiving piece; 121, chamber; 2, restraining rod; 21, slide groove; 3, material collection piece; 31, pushing rod; 32, material collection part; 321, connecting piece; 322, sampling piece; 3221, water-soluble shell; 3222, sponge; 4, container body; 41, sealing cover. DETAILED DESCRIPTION
[0027] The technical solutions in the embodiments of the utility model are clearly and completely described below through specific embodiments. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Those skilled in the art can easily understand other advantages and functions of the utility model from the contents disclosed in this specification. The utility model can also be implemented or applied through other different specific implementation methods. In the absence of conflict, the following embodiments and features in the embodiments can be combined with each other. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0028] Figure 1 —4 shows the main technical content of the present embodiment. The present specific embodiment provides an oral mucosal cell sampling tool, which includes: an outer sleeve 1, the outer sleeve 1 has a first end and a second end, wherein a accommodating cavity is opened from the first end to the second end; a constraint rod 2, arranged in the accommodating cavity, wherein four slide grooves 21 are opened on the outer surface of the constraint rod 2; four sampling components 3, each of which includes: a sampling portion 32 and a pushing rod 31, the sampling portion 32 is arranged at one end of the pushing rod 31, wherein the pushing rod 31 is arranged in the slide groove 21, and the sampling portion 32 is located outside the accommodating cavity, when the pushing rod 31 moves along the slide groove 21 toward the first end relative to the constraint rod 2, the sampling portion 32 moves away from the first end of the outer sleeve 1; as can be understood by those skilled in the art, the number of slide grooves 21 corresponds to the number of sampling components 3, and the number of the two is not limited to 4, and can be adaptively adjusted according to actual needs.
[0029] When in use, for example, to take a sample of mucosal cells from the right side of the patient's oral cavity (inner side of the right cheek), the pushing rod 31 of a sampling piece 3 is driven to move relative to the restraining rod 2 along the slide groove 21 toward the first end. At this time, the sampling portion 32 is away from the first end of the outer sleeve 1, and is then provided for medical personnel to use for sampling. The medical personnel holds the outer sleeve 1 to perform the sampling operation. After the sampling is completed, the sampling portion 32 is folded off the pushing rod 31 to place the sampling portion 32 with mucosal cells into a corresponding storage container for storage. Then, the remaining sampling pieces 3 are used to sample other parts of the patient's oral cavity in turn, and the samples are placed in corresponding storage containers.
[0030] refer to Figure 2 —5, in this embodiment, it also includes a receiving member 12, which is arranged at the first end of the outer sleeve 1, and has a chamber 121, which is connected to the accommodating chamber, wherein the material collecting portion 32 is located in the chamber 121, and when the push rod 31 moves relative to the constraint rod 2 along the slide groove 21 toward the first end, the material collecting portion 32 extends out from the chamber 121, Figure 2 —5. It can be seen that the sampling portion 32 of each sampling piece 3 is located in the cavity 121 when not in use. When in use, the sampling portion 32 of one sampling piece 3 is pushed out of the cavity 121 by the pushing rod 31. At this time, the sampling portion can be used to sample the oral mucosal cells of the patient. At the same time, the sampling portions of the remaining sampling pieces 3 are all in the cavity 121, thereby preventing the remaining sampling portions 32 from contacting the patient's oral cavity, thereby preventing the remaining sampling pieces 3 from being contaminated.
[0031] Specifically, the receiving member 12 and the outer sleeve 1 are integrally formed.
[0032] refer to Figure 2 —7, in the present embodiment, four limiting grooves 11 are provided from the outer wall of the outer sleeve 1 to the accommodating cavity, wherein each limiting groove 11 corresponds to a slide groove 21, and a portion of the push rod 31 extends out of the limiting groove 11. When in use, the medical staff applies force to a portion of the push rod 31 extending out of the limiting groove 11, for example, to move the push rod 31 toward the first end direction. At this time, the material collection portion 32 on the push rod 31 is pushed out of the cavity 121. On the contrary, when the push rod 31 is moved toward the second end direction, the material collection portion 32 on the push rod 31 is pushed out of the cavity 121. 2 will enter the chamber 121. Under this setting mode, it is convenient for medical personnel to use each sampling piece 322 to perform sampling operations on different positions in the patient's oral cavity in turn, and then the medical personnel can distinguish the sampling area corresponding to each sampling piece 3. Therefore, during the storage process, the medical personnel can clearly know the oral part corresponding to the mucosal cell sample on each sampling piece 3; as can be understood by those skilled in the art, the number of limiting grooves 11 corresponds to the number of sliding grooves 21, and the number of the two is not limited to 4, and can be adaptively adjusted according to actual needs.
[0033] More specifically, the limiting grooves 11 are distributed in a circular array on the outer wall of the outer sleeve 1 .
[0034] refer to Figure 5—6. In the present embodiment, the pushing rod 31 comprises: a connecting end and a pushing end, wherein the connecting end extends out from the accommodating cavity, the material collecting portion 32 is connected to the connecting end, the pushing end extends out from the limiting groove 11, and the pushing end can move linearly in the limiting groove 11 toward the first end and the second end, so as to make the material collecting portion 32 move away from the first end and approach the first end. More specifically, the pushing end comprises a push button. When in use, the medical staff applies force to the pushing rod 31 as a whole through the push button to facilitate pushing the pushing rod 31.
[0035] refer to Figure 6 Specifically, a break line is provided around the outer wall of the push rod 31, wherein the break line is closer to the connection end than the push end. When in use, after the medical staff completes sampling a part in the patient's oral cavity, the sample part can be separated from the push rod 31 through the break line, which facilitates the placement of the sample part containing oral mucosal cells into a storage container. As can be understood by those skilled in the art, since the break line does not coincide with the connection end, after the push rod 31 is broken, a part of the push rod still falls into the storage container with the sample part.
[0036] Specifically, the outer wall of each push rod 31 also has an identification groove, and the cross-sectional shape of each identification groove is different. After separating the sampling part from the push rod 31, medical personnel can identify the shape of the cross-sectional shape of the identification groove through the storage container to know the oral position corresponding to the sampling part.
[0037] Alternatively, each push rod has a different color. After the sampling portion is separated from the push rod 31, medical personnel can identify the color of the push rod 31 through the storage container to determine the location in the patient's oral cavity from which the mucosal cells in the storage container are taken, thereby avoiding confusion of the mucosal cell samples.
[0038] Alternatively, the pushing end of each pushing rod is engraved with letters or numbers.
[0039] refer to Figure 6 —7. In the present embodiment, the sampling portion 32 comprises: a connecting piece 321 and a sampling piece 322, the connecting piece 321 is connected to the connecting end, the sampling piece 322 is used for sampling oral mucosal cells, wherein the sampling piece 322 is connected to the connecting piece 321; specifically, the connecting piece 321 is in the shape of an arc plate, the sampling piece 322 is in the shape of a capsule, and the sampling piece 322 is arranged on one side of the connecting piece 321 by bonding. Specifically, when in use, when the medical staff pushes a pushing rod 31, the connecting piece 321 and the sampling piece 322 move synchronously with the pushing rod 31 until the connecting piece 321 reaches a suitable position relative to the outer sleeve 1.
[0040] refer to Figure 7—8. More specifically, the sampling piece 322 includes: a water-soluble shell 3221 and a sponge 3222; the water-soluble shell 3221 is made of a material selected from the group consisting of polyvinyl alcohol, hydroxypropyl methylcellulose, polyethylene glycol, and starch-based materials. Under this configuration, the water-soluble shell 3221 can be completely or partially dissolved after contacting with the patient's body fluids.
[0041] Sponge 3222 is a polyurethane sponge 3222, which is loaded in a water-soluble shell 3221 by compression. When in use, when the water-soluble shell 3221 is in full contact with the patient's oral secretions, it partially dissolves. At this time, the sponge 3222 bulges out from the dissolved position of the water-soluble shell 3221, and then allows medical personnel to collect tissue cells on the patient's oral mucosa. In addition, due to the strong adsorption and soft properties of the polyurethane sponge 3222, it can strongly adsorb the collected tissue cells during the collection process, while also improving the patient's comfort and avoiding damage to the patient's oral mucosa.
[0042] In addition, reference Fig. 9 , a sample storage container is also provided, which includes: a container body 4 and a sealing cover 41, the container body 4 and the sealing cover 41 are connected by a flexible plastic section, and when in use, the sealing cover 41 can seal the container body 4; more specifically, the container body 4 has four chambers, and when in use, mucosal cells obtained from different positions in the oral cavity can be stored in each chamber respectively, so as to facilitate medical personnel to further distinguish mucosal cells in different positions in the oral cavity; more specifically, the outer wall of the container body 4 is also provided with a mark corresponding to the chamber, for example, different letters or different digital marks are engraved on the outer wall of the container body 4, and each letter or number corresponds to a chamber. Preferably, the outer wall of the container body 4 is engraved with different letter marks, and accordingly, the pushing end of each push rod is also engraved with different letter marks. When in use, the material collection part 32 of the push rod with the same letter mark as the chamber is stored in the corresponding chamber.
[0043] The use of the utility model:
[0044] 1. The medical staff holds the outer sleeve and then drives a push rod of a material collection member to move along the slide groove toward the first end relative to the restraining rod until the material collection part moves to a suitable position.
[0045] 2. Hold the outer sleeve so that the water-soluble shell fully contacts and dissolves the patient's oral mucosa. At this time, the sponge bulges out from the position where the water-soluble shell dissolves, allowing medical personnel to collect tissue cells on the patient's oral mucosa. After the collection of samples from one part of the oral cavity is completed, the collection part is folded off the push rod through the breaking line and placed in a storage container, thereby completing the collection of mucosal cells from one part of the oral cavity.
[0046] 3. Repeat the above operations in sequence, use the remaining sampling pieces to sample other parts of the patient's oral cavity in sequence, and place them into the corresponding chambers of the accommodating body, thereby completing the sampling operation.
[0047] The above embodiments are only used to understand the present invention. It should be noted that, for those skilled in the art, several improvements can be made to the present invention without departing from the principle of the present invention, and these improvements will also fall within the scope of protection of the claims of the present invention.
Claims
1. A tool for collecting oral mucosal cells, characterized in that: It comprises an outer sleeve, the outer sleeve having a first end and a second end, wherein a receiving cavity is opened from the first end to the second end; A restraining rod is disposed in the accommodating cavity, wherein a plurality of sliding grooves are provided on the outer surface of the restraining rod; A plurality of material collecting members, each of which comprises: a material collecting portion and a pushing rod, wherein the material collecting portion is arranged at one end of the pushing rod, wherein the pushing rod is arranged in the sliding groove, and the material collecting portion is located outside the accommodating cavity, and when the pushing rod moves along the sliding groove toward the first end relative to the restraining rod, the material collecting portion is away from the first end of the outer sleeve.
2. The oral mucosal cell sampling tool according to claim 1, characterized in that: It also includes a receiving piece, which is configured at the first end of the outer sleeve, and the receiving piece has a chamber, which is communicated with the accommodating chamber, wherein the material collecting part is located in the chamber, and when the pushing rod moves along the sliding groove toward the first end relative to the restraining rod, the material collecting part extends out from the chamber.
3. The oral mucosal cell sampling tool according to claim 1, characterized in that: A plurality of limiting grooves are provided from the outer wall of the outer sleeve toward the accommodating cavity, wherein each limiting groove corresponds to one sliding groove, and a portion of the push rod extends out from the limiting groove.
4. The oral mucosal cell sampling tool according to claim 3, characterized in that: A plurality of the limiting grooves are distributed in a circular array on the outer wall of the outer sleeve.
5. The oral mucosal cell sampling tool according to claim 3, characterized in that: The pushing rod includes: a connecting end and a pushing end, wherein the connecting end extends out from the accommodating cavity, the material collecting portion is connected to the connecting end, the pushing end extends out from the limiting groove, and the pushing end can move linearly in the limiting groove toward the first end direction and the second end direction, so that the material collecting portion moves away from the first end and approaches the first end.
6. The oral mucosal cell sampling tool according to claim 5, characterized in that: A breaking line is arranged around the outer wall of the pushing rod, wherein the breaking line is closer to the connecting end than to the pushing end.
7. The oral mucosal cell sampling tool according to claim 1, characterized in that: The outer wall of each push rod also has an identification groove, wherein the cross-sectional shape of each identification groove is different.
8. The oral mucosal cell sampling tool according to claim 5, characterized in that: The material collection unit comprises: A connecting piece connected to the connecting end; The sampling piece is used for collecting oral mucosal cells, wherein the sampling piece is connected to the connecting piece.
9. The oral mucosal cell sampling tool according to claim 8, characterized in that: The sampling component includes: a water-soluble shell and a sponge, wherein the water-soluble shell is bonded to the connecting component, and the sponge is arranged in the water-soluble shell.
10. The oral mucosal cell sampling tool according to claim 3, characterized in that: The number of the sliding grooves, the material taking members and the limiting grooves is the same.