Spraying device for spraying spray to skin

Abstract

The utility model relates to a spraying device for spraying a spray to skin, which comprises an ink-jet device and a nozzle arranged at an outlet of the ink-jet device. The ink spraying equipment is used for extruding a material of the spraying agent; and the nozzle is used for spraying the extruded material onto the skin in a spraying manner. According to the utility model, spray delivery can be combined with the hydrogel stent, the hydrogel stent has the advantages of particle delivery uniformity, hydrogel fixation and cell protection, has good biocompatibility, and can spray and quickly form gel in situ.

Description

Technical Field

[0001] The utility model relates to the technical field of spraying devices, in particular to a spraying device for spraying spray onto skin. Background Art

[0002] The skin is in direct contact with the outside world, blocking external stimuli and the invasion of foreign bodies, and plays an important role in maintaining human health. At present, the healing of chronic skin wounds is still a problem to be solved clinically. For skin injuries caused by trauma, burns, chronic ulcers, and surgical trauma, the most commonly used method of clinical treatment is skin transplantation. However, skin transplantation has problems such as limited autologous tissue, insufficient donors, and damage to the grafted area. Therefore, how to quickly and high-quality repair chronic and difficult-to-heal wounds is still a major challenge.

[0003] Wound dressings are materials that cover wounds, protect wound surfaces, and reduce infection and other injuries. They are very common in wound care. To date, wound dressings can be divided into different types to promote wound healing. Traditional dressings such as sterile gauze can act as a simple physical barrier for wounds, but they cannot effectively promote wound healing and are prone to secondary damage when changing dressings. In contrast, hydrogel dressings have a high water content, which can maintain a moist environment at the wound site. Their swelling properties allow them to absorb exudate, reducing damage to the wound when changing dressings. And according to the material properties of the hydrogel, it can be modified to load drugs or functional groups to promote wound healing.

[0004] The development of regenerative medicine has provided a potential strategy for skin injury repair. Natural polymer materials such as collagen, gelatin, and fibrin and synthetic polymer materials such as polyethanol and polylactic acid have been widely used to prepare functional skin or dressings; however, wound healing is a complex process that requires the coordination and integration of biological and molecular events such as cell migration and proliferation, extracellular matrix (ECM) deposition and remodeling, wound contraction, angiogenesis, and immune regulation, which is difficult to achieve with materials and drugs alone. With the continuous deepening of stem cell research, people have found that stem cells can play a very important role in chronic wound healing, among which mesenchymal stem cells (MSC) have attracted the most attention. When introduced into the wound bed, MSCs have been shown to promote fibroblast migration, stimulate ECM deposition, promote wound closure, and initiate epithelial re-formation; in preclinical animal models, MSCs have shown the ability to enhance angiogenesis and reduce inflammation, and clinical studies involving human subjects have also confirmed that MSCs are effective and safe in promoting chronic wound healing.

[0005] However, it is still unclear which technology is the safest and most effective for delivering MSCs to wound beds. Currently, there are several methods for delivering MSCs: first, intravenous injection and local intradermal injection in the wound area are performed using an injection device. This method cannot guarantee the time for the cells to be effective in situ in the wound. In order to improve the delivery efficiency of MSCs in the wound site, a spray device is used to spray fibrin to achieve local MSC delivery, but this method cannot evenly coat the cells in the wound. Utility Model Content

[0006] In view of the above problems, the purpose of the utility model is to provide a portable spray device for spraying sprays onto the skin, which has an integrated gas source generating system, an independent human-computer interaction interface, multiple adjustable and precisely controlled parameters, and replaceable nozzles to adapt to the spraying of various biological materials; in addition, the device can combine spray delivery with a hydrogel scaffold, has the advantages of uniformity of particle delivery and hydrogel fixation and cell protection, has good biocompatibility, can be sprayed, and can quickly gel in situ.

[0007] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0008] The utility model discloses a spraying device for spraying a spray onto the skin, comprising an inkjet device and a nozzle, wherein the nozzle is arranged at the outlet of the inkjet device; the inkjet device is used to extrude the spray material; and the nozzle is used to spray the extruded material onto the skin in a spraying manner.

[0009] The nozzle is a second internal mixing nozzle or a second external mixing nozzle;

[0010] The second external mixing nozzle comprises a third nozzle body, wherein a first reagent channel for reagent circulation is provided at the center of the third nozzle body, a third gas channel for gas circulation is provided at the periphery of the first reagent channel, and the first reagent channel and the third gas channel respectively penetrate the third nozzle body, so that the gas and the reagent are mixed outside the third nozzle body;

[0011] The second internal mixing nozzle includes a fourth nozzle body, a second reagent channel for reagent circulation is arranged at the center of the fourth nozzle body, a fourth gas channel for gas circulation is arranged on the periphery of the second reagent channel, and the second reagent channel is connected with the fourth gas channel inside the fourth nozzle body to mix the gas and the reagent inside the fourth nozzle body.

[0012] The inkjet device is an air pump type inkjet device;

[0013] The air pump type inkjet device comprises:

[0014] The second shell is in the shape of two halves of a gun;

[0015] A second extruding mechanism, horizontally and fixedly disposed in the second housing;

[0016] A second front cover assembly, openably disposed at the front end of the second housing;

[0017] a second syringe, threadedly connected to the second front cover assembly;

[0018] An air pump is fixedly arranged at the handle position of the second housing;

[0019] A gas storage tank, disposed below the front portion of the second shell and fixedly connected to the second shell;

[0020] A front cover release mechanism, inserted into the second housing and sliding in the second housing to lock and release the second front cover assembly;

[0021] A second trigger assembly is rotatably disposed on the second housing and is used to trigger the air pump and / or the second extrusion mechanism;

[0022] The second display screen is connected to the rear end of the second shell and is used to set the parameters of the extrusion program and air pressure.

[0023] In the spraying device, preferably, the second extrusion mechanism comprises:

[0024] A second extrusion base;

[0025] A second micro-stepping screw motor is fixedly arranged on the second extrusion base;

[0026] The second slider is threadedly connected to the screw of the second micro-stepping screw motor and can slide under the drive of the screw of the second micro-stepping screw motor; the second slider is provided with a light hole;

[0027] The extrusion optical axis is arranged parallel to the screw of the second micro-stepping screw motor and is fixedly mounted on the second extrusion base; the extrusion optical axis passes through the optical hole of the second slider;

[0028] A second driving circuit board is fixedly arranged at the bottom of the second extrusion base, and a touch switch is arranged on the second driving circuit board, and the touch switch is used to trigger the second extrusion mechanism to work;

[0029] A cover plate, fixedly arranged on the top of the second extrusion base, two sides of the cover plate are connected to the second shell, and the cover plate is provided with slots;

[0030] The second sample needle seat is fixedly connected to the second slider, and is used to lock the piston rod of the second syringe and drive the piston rod of the second syringe to reciprocate under the action of the second micro-stepping screw motor and the second slider.

[0031] The spraying device, preferably, the second driving circuit board is also provided with a second photoelectric sensor and an air pressure sensor;

[0032] The second photoelectric sensor is used to detect the home position and maximum stroke of the second slider;

[0033] The air pressure sensor is used to communicate with the inner cavity of the air storage tank through the second air storage tank joint to detect the air pressure in the air storage tank.

[0034] The spraying device, preferably, the second front cover assembly comprises a second front cover, a mixing block, a second front cover joint and a second front cover rotating shaft;

[0035] The mixing block is arranged on the second front cover, and a Y-shaped channel is arranged in the mixing block;

[0036] One end of the second front cover joint is respectively connected to an interface of a channel at the lower end of the mixing block, and the other end of the second front cover joint is used to connect to the third air tank joint through an air pipe to connect compressed air to the mixing block;

[0037] The second front cover is connected to the second housing via a second front cover rotation shaft, so that the second front cover can rotate around the second front cover rotation shaft.

[0038] The spraying device, preferably, the gas tank comprises a gas tank housing, a battery assembly, a power management board, a first gas tank connector, a second gas tank connector, a third gas tank connector, a one-way solenoid valve and a connector;

[0039] The gas storage tank shell is a shell structure with a built-in hollow sealed cavity;

[0040] One end of the first gas storage tank joint is connected to the sealed cavity, and the other end thereof is connected to the air pump through an air pipe to form an inflation circuit;

[0041] One end of the second gas storage tank connector is connected to the sealed cavity, and the other end thereof is connected to the air pressure sensor through an air pipe to form an air pressure detection circuit;

[0042] One end of the third gas tank joint is connected to the sealed cavity, and the other end thereof is connected to the inlet of the one-way solenoid valve through an air pipe, and the outlet of the one-way solenoid valve is connected to the second front cover joint;

[0043] The battery assembly is fixedly arranged at the bottom of the gas storage tank shell to supply power to the electrical components of the whole machine;

[0044] The power management board is fixedly arranged at the bottom of the gas tank housing to provide power management for the whole machine;

[0045] The connector is electrically connected to the power management board, and the connector is electrically connected to the electrical components of the second extrusion mechanism and the air pump to supply power for the electrical connection between the second extrusion mechanism and the air pump.

[0046] In the spraying device, preferably, the front cover release mechanism comprises: a front cover release lever, a release optical axis and a compression spring;

[0047] The bottom of the mixing block has at least two protrusions, and the protrusions have inverted slopes;

[0048] The front cover release lever has at least two hook-shaped structures, and the inner side of the hook-shaped structure has an inverted slope corresponding to the protrusion;

[0049] One end of the release optical axis passes through the bottom of the front cover release rod and is fixed to the front cover release rod;

[0050] The other end of the release optical axis is fixed to the second housing;

[0051] The compression spring is sleeved on the release optical axis.

[0052] In the spraying device, preferably, the second sample needle seat comprises a second sample needle seat base, a second sample needle cover and a second sample needle seat rotating shaft;

[0053] The second sample needle cover is connected to the second sample needle seat base via a second sample needle seat rotating shaft so that the second sample needle cover can be openably arranged on the second sample needle seat base. When the second sample needle cover is closed, the piston rod of the second syringe is locked by the second sample needle cover and the second sample needle seat base.

[0054] The spraying device, preferably, the second trigger assembly includes a second trigger, a firing pin, a second trigger optical axis and a second torsion spring;

[0055] One end of the second trigger optical axis is fixed to the second housing, and the other end passes through the second trigger, so that the second trigger can rotate around the second trigger optical axis;

[0056] The firing pin is arranged on the top of the second trigger and is used to strike the touch switch on the second driving circuit board;

[0057] The second torsion spring is sleeved on the second trigger optical axis, one end of the second torsion spring is fixed to the second housing, and the other end is fixed to the second trigger to provide power for resetting the second trigger.

[0058] The utility model adopts the above technical solution, which has the following advantages:

[0059] (1) By designing the inkjet device and nozzle parameters, multi-material cell-carrying inkjet can be achieved. The device is simple and portable, the nozzle is replaceable, and the parameters are adjustable, which is suitable for clinical operation.

[0060] (2) The utility model supports independent control and coordinated extrusion of one, two or more materials, and can achieve automatic adjustment of material concentration.

[0061] (3) The design of various parameters of the spray gun can better ensure the high activity of cells. BRIEF DESCRIPTION OF THE DRAWINGS

[0062] By reading the detailed description of the preferred embodiment below, various other advantages and benefits will become clear to those of ordinary skill in the art. The accompanying drawings are only used for the purpose of illustrating the preferred embodiment and are not considered to be limiting of the present invention. The same reference numerals are used throughout the accompanying drawings to represent the same components. In the accompanying drawings:

[0063] Figure 1 It is a schematic diagram of the external structure of the fan-type inkjet device described in the utility model;

[0064] Figure 2 It is a schematic diagram of the internal structure of the fan-type inkjet device described in the utility model;

[0065] Figure 3 It is a three-dimensional structural schematic diagram of the first extrusion mechanism of the fan-type inkjet device described in the utility model;

[0066] Figure 4 It is a schematic diagram of the main structure of the first extrusion mechanism of the fan-type inkjet device of the utility model;

[0067] Figure 5 It is a structural schematic diagram of the first front cover assembly of the fan-type inkjet device described in the utility model;

[0068] Figure 6 yes Figure 5 A schematic diagram of the structure of the connection block in FIG.

[0069] Figure 7 It is a three-dimensional structural schematic diagram of the gas generating assembly of the fan-type inkjet device described in the utility model;

[0070] Figure 8It is a cross-sectional structural schematic diagram of the gas generating assembly of the fan-type inkjet device described in the utility model;

[0071] Fig. 9 It is a structural schematic diagram of the first sample needle seat of the fan-type inkjet device of the utility model, wherein the first sample needle cover is in an open state;

[0072] Fig.10 It is a structural schematic diagram of the first sample needle seat of the fan-type inkjet device of the utility model, wherein the first sample needle cover is in a closed state;

[0073] Fig.11 It is a three-dimensional structural schematic diagram of the first trigger assembly of the fan-type inkjet device described in the utility model;

[0074] Fig.12 It is a schematic diagram of the main structure of the first trigger assembly of the fan-type inkjet device of the utility model;

[0075] Fig.13 It is a structural schematic diagram of a power supply assembly of a fan-type inkjet device according to the utility model;

[0076] Fig.14 It is a schematic diagram of the external structure of the air pump type inkjet device described in the utility model;

[0077] Fig.15 It is a schematic diagram of the internal structure of the air pump type inkjet device described in the utility model;

[0078] Fig.16 It is a three-dimensional structural schematic diagram of the second extrusion mechanism of the air pump type inkjet device described in the utility model;

[0079] Fig.17 yes Fig.16 A schematic diagram of the structure of the second driving circuit board in FIG.

[0080] Fig.18 It is a structural schematic diagram of the air storage tank of the air pump type inkjet device described in the utility model;

[0081] Fig.19 It is a three-dimensional structural schematic diagram of the cooperation between the front cover release mechanism and the second front cover assembly of the air pump type inkjet device of the utility model;

[0082] Fig. 20 yes Fig.19 Schematic diagram of the structure of the mixing block in ;

[0083] Fig.21 It is a cross-sectional structural diagram of the cooperation between the front cover release mechanism and the second front cover assembly of the air pump type inkjet device of the utility model, wherein the front cover release mechanism is in a locked state;

[0084] Fig. 22 It is a cross-sectional structural diagram of the cooperation between the front cover release mechanism and the second front cover assembly of the air pump type inkjet device of the utility model, wherein the front cover release mechanism is in an unlocked state;

[0085] Fig.23 It is a structural schematic diagram of the second sample needle seat of the air pump type inkjet device of the utility model, wherein the second sample needle cover is in an open state;

[0086] Fig.24 It is a structural schematic diagram of the second sample needle seat of the air pump type inkjet device of the utility model, wherein the second sample needle cover is in a closed state;

[0087] Fig.25 It is a structural schematic diagram of the second trigger assembly of the air pump type inkjet device of the utility model;

[0088] Fig.26 It is a structural schematic diagram of the external mixing nozzle corresponding to the fan-type inkjet device in the utility model;

[0089] Fig. 27 This is a schematic diagram of the structure of the internal mixing nozzle corresponding to the fan-type inkjet device in the utility model.

[0090] Fig.28 It is a structural schematic diagram of the external mixing nozzle corresponding to the air pump type inkjet device in the utility model;

[0091] Fig.29 It is a structural schematic diagram of the internal mixing nozzle corresponding to the air pump type inkjet device in the utility model.

[0092] Fig.30 This is a result diagram of the utility model's test on the inkjet device;

[0093] Fig.31 It is a schematic diagram of the single-barrel and three-barrel extrusion mechanism of the air pump type inkjet device of the present invention.

[0094] The symbols in the accompanying drawings are as follows:

[0095] 1-fan-type inkjet device; 1-1-first housing; 1-2-first extrusion mechanism; 1-201-first extrusion base; 1-202-first micro-stepping screw motor; 1-203-linear guide; 1-204-first slider; 1-205-first drive circuit board; 1-2051-first photoelectric sensor; 1-206-first needle seat; 1-2061-first needle seat base; 1-2062-first needle cover; 1-2063-first needle seat shaft; 1-3-first syringe; 1-4-first front cover assembly; 1-401-connecting block; 1-402-first front cover; 1-403-front cover buckle; 1-404-first front cover shaft; 1-4 05-first front cover connector; 1-5-gas generating assembly; 1-501-air duct; 1-502-ducted fan; 1-504-fan driving plate; 1-505-liquid connecting joint; 1-6-wind force regulating device; 1-601-wind force regulator; 1-602 wind force regulating lever; 1-7-first trigger assembly; 1-701-first trigger; 1-702-micro switch; 1-703-first trigger optical axis; 1-704-first torsion spring; 1-8-first display screen; 1-9-power supply assembly; 1-901-battery tray; 1-902-battery; 1-903-battery shrapnel; 1-904-battery buckle; 1-10-nozzle for fan-type inkjet device;

[0096] 2-air pump inkjet device; 2-1-second housing; 2-2-second extrusion mechanism; 2-201-second extrusion base; 2-202-second micro-stepping screw motor; 2-203-extrusion optical axis; 2-204-second slider; 2-205-second drive circuit board; 2-2051-second photoelectric sensor; 2-2052-air pressure sensor; 2-2053-touch switch; 2-206-cover plate; 2-207-second sample needle seat; 2-2071-second sample needle seat base; 2-2072-second sample needle cover; 2-2073-second sample needle seat shaft; 2-3-second syringe; 2-4-air pump; 2-5-gas tank; 2-501-gas tank housing; 2-502-battery assembly; 2-503-power management board; 2-5031-power switch; 2-5032-charging interface; 2-5033-charging indicator light; 2-504 first gas tank connector; 2-505-second gas tank connector; 2-506-third gas tank connector; 2-507-one-way solenoid valve; 2-508-connector; 2-6-second front cover assembly; 2-601-second front cover; 2-602-mixing block; 2-603-second front cover connector; 2-604 second front cover shaft; 2-7-front cover release mechanism; 2-701-front cover release lever; 2-702-release optical axis; 2-703-compression spring; 2-8-second trigger assembly; 2-801-second trigger; 2-802-firing pin; 2-803-second trigger optical axis; 2-804-second torsion spring; 2-9-second display screen; 2-10-nozzle for air pump inkjet device. DETAILED DESCRIPTION

[0097] The exemplary embodiments of the present invention will be described in more detail below with reference to the accompanying drawings. Although the exemplary embodiments of the present invention are shown in the accompanying drawings, it should be understood that the present invention can be implemented in various forms and should not be limited by the embodiments described herein. On the contrary, these embodiments are provided to enable a more thorough understanding of the present invention and to fully convey the scope of the present invention to those skilled in the art.

[0098] The utility model provides a spraying device for spraying a spray onto the skin, an inkjet device and a nozzle, wherein the nozzle is arranged at the outlet of the inkjet device; the spray delivery is combined with a hydrogel scaffold through the inkjet device, and has the advantages of uniform particle delivery and hydrogel fixation and cell protection, good biocompatibility, sprayability, and rapid in-situ gelation.

[0099] The utility model provides a spraying device for spraying spray onto skin, comprising an inkjet device and a nozzle, wherein the nozzle is arranged at the outlet of the inkjet device; the inkjet device is used for extruding the spray material; and the nozzle is used for spraying the extruded material onto the skin in a spraying manner.

[0100] In the above embodiments, preferably, the inkjet device is a fan-type inkjet device 1 or an air pump-type inkjet device 2; the nozzles are nozzles 1-10 for fan-type inkjet devices or nozzles 2-10 for air pump-type inkjet devices.

[0101] In the above embodiment, preferably, Figure 1 and Figure 2 As shown, the fan-type inkjet device includes: a first shell 1-1, which is a two-half structure in the shape of a gun; a first extrusion mechanism 1-2, which is vertically fixed in the first shell 1-1; a first front cover assembly 1-4, which is clamped on the front end of the first shell 1-1; a first syringe 1-3, which is threadedly connected to the first front cover assembly 1-4; a gas generating assembly 1-5, which is horizontally fixed in the first shell 1-1; a wind force regulating device 1-6, which is fixedly arranged in the first shell 1-1 and is located below the gas generating assembly 1-5; a first trigger assembly 1-7, which is rotatably arranged on the first shell 1-1, and is used to start the gas generating assembly 1-5 and the first extrusion mechanism 1-2; a first display screen 1-8, which is clamped on the rear end of the first shell 1-1, and is used to set the extrusion program and / or wind force regulation parameters; a power supply assembly 1-9, which is arranged at the handle position of the first shell 1-1, and is used to power the entire machine.

[0102] Among them, the nozzle 1-10 for the fan-type inkjet device is arranged at the outlet end of the first shell 1-1.

[0103] In the above embodiment, preferably, Figure 3 and Figure 4 As shown, the first extrusion mechanism 1-2 includes: a first extrusion base 1-201; a first micro-stepping screw motor 1-202, which is fixedly arranged on the first extrusion base 1-201; a first slider 1-204, which is threadedly connected to the screw of the first micro-stepping screw motor 1-202 and can slide under the drive of the screw of the first micro-stepping screw motor 1-202; a linear guide rail 1-203, which is arranged parallel to the screw of the first micro-stepping screw motor 1-202 and is fixedly installed on the first extrusion base 1-201, and the first slider 1-204 slides on the linear guide rail 1-203; the first The driving circuit board 1-205 is fixedly arranged at the bottom of the first extrusion base 1-201. The first driving circuit board 1-205 is provided with a first photoelectric sensor 1-2051, and the first photoelectric sensor 1-2051 is used to detect the original position and the maximum stroke position of the first slider 1-204; the first needle seat 1-206 is fixedly connected to the first slider 1-204. The first needle seat 1-206 is used to lock the piston rod of the first syringe 1-3, and drive the piston rod of the first syringe 1-3 to reciprocate under the action of the first micro stepping screw motor 1-202 and the first slider 1-204.

[0104] In the above embodiment, preferably, Figure 5 and Figure 6 As shown, the first front cover assembly 1-4 includes a connecting block 1-401, a first front cover 1-402, a front cover buckle 1-403, a first front cover shaft 1-404 and a first front cover joint 1-405; the connecting block 1-401 is fixedly arranged on the first front cover 1-402, and a mixing chamber is provided in the connecting block 1-401; one end of the first front cover joint 1-405 is connected to the connecting block 1-401, and the other end thereof is used to connect to the gas generating assembly 1-5 The liquid connecting joint 1-505 is connected to form a reagent transport channel; the first front cover 1-402 is connected to the first shell 1-1 through the first front cover shaft 1-404, so that the first front cover 1-402 can rotate around the first front cover shaft 1-404; the front cover buckle 1-403 is fixedly set on the first front cover 1-402, and the first front cover 1-402 is connected to the first shell 1-1 through the front cover buckle 1-403 to achieve snap-in and loosening.

[0105] In the above embodiment, preferably, Figure 7 and Figure 8 As shown, the gas generating assembly 1-5 includes an air duct 1-501, a ducted fan 1-502, a fan drive plate 1-504 and a liquid connecting joint 1-505; the front end of the air duct 1-501 is designed with a tapered end; the ducted fan 1-502 is fixedly arranged at the rear of the air duct 1-501 to provide high-speed airflow; the fan drive plate 1-504 is fixed at the bottom of the air duct 1-501 to drive the ducted fan 1-502; one end of the liquid connecting joint 1-505 is used to connect to the first pipe of the first external mixing nozzle or the second pipe of the first internal mixing nozzle, and the other end is connected to the first front cover joint 1-405.

[0106] In the above embodiment, preferably, Figure 7 As shown, the wind force regulating device 1-6 includes a wind force regulator 1-601 and a wind force regulating lever 1-602; the wind force regulator 1-601 is fixed to the first housing 1-1 and is electrically connected to the fan driving plate 1-504; the wind force regulating lever 1-602 is connected to the wind force regulator 1-601, so that when the wind force regulating lever 1-602 is turned, the wind force can be adjusted. Alternatively, the wind force regulator 1-601 is electrically connected to the first display screen 1-8, and the wind force is displayed and controlled through the first display screen 1-8.

[0107] In the above embodiment, preferably, Fig. 9 and Fig.10As shown, the first needle seat 1-206 includes a first needle seat base 1-2061, a first needle cover 1-2062 and a first needle seat rotating shaft 1-2063; the first needle cover 1-2062 is connected to the first needle seat base 1-2061 through the first needle seat rotating shaft 1-2063, so that the first needle cover 1-2062 can be openably arranged on the first needle seat base 1-2061, and when the first needle cover 1-2062 is closed, the piston rod of the first syringe 1-3 is locked by the first needle cover 1-2062 and the first needle seat base 1-2061.

[0108] In the above embodiment, preferably, Fig.11 and Fig.12 As shown, the first trigger assembly 1-7 includes a first trigger 1-701, a micro switch 1-702, a first trigger optical axis 1-703 and a first torsion spring 1-704; one end of the first trigger optical axis 1-703 is fixed to the first housing 1-1, and the other end passes through the first trigger 1-701, so that the first trigger 1-701 can rotate around the first trigger optical axis 1-703; the micro switch 1-702 is arranged at the rear end of the first trigger 1-701, and the micro switch 1 -702 has a spring trigger sheet, and the micro switch 1-702 is electrically connected to the first micro stepping screw motor 1-202 and the fan drive plate 1-504; the first trigger 1-701 is pulled to hit the spring trigger sheet, thereby triggering the inkjet signal; the first torsion spring 1-704 is mounted on the first trigger optical axis 1-703, one end of which is fixed to the first housing 1-1, and the other end is fixed to the first trigger 1-701, so as to provide power for resetting the first trigger 1-701.

[0109] In the above embodiment, preferably, Fig.13 As shown, the power supply assembly 1-9 includes a battery tray 1-901, a battery 1-902, a battery spring 1-903 and a battery clip 1-904; the battery tray 1-901 has a cavity for accommodating the battery 1-902; the battery spring 1-903 is fixedly arranged inside the battery tray 1-901, and is used to connect several batteries 1-902 in series; the battery 1-902 is detachably arranged in the battery tray 1-901; the battery tray 1-901 is connected to the first shell 1-1 through the battery clip 1-904 to achieve snap-on and loosening.

[0110] When the fan-type inkjet device is working, the extrusion parameters are set through the first display screen 1-8, and the wind force is set through the wind force adjustment device 1-6. After the setting is completed, the first trigger 1-701 is pulled, the duct fan 1-502 is started, and a high-speed airflow is formed by the shrinkage of the air duct 1-501. At the same time, the first extrusion mechanism 1-2 starts to work. According to the parameters set on the display screen 1-8, driven by the first micro-stepping screw motor 1-202, the first needle seat 1-206 starts to move from right to left, driving the piston rod of the first syringe 1-3 to move, thereby completing the extrusion action. The liquid squeezed out of the first syringe 1-3 passes through the connecting block 1-401 and is connected to the air duct 1-501 through the liquid connecting joint 1-505. The liquid is mixed through the channel inside the air duct 1-501, atomized under the action of the high-speed airflow, and sprayed out from the left side of the instrument.

[0111] In the above embodiment, preferably, Fig.14 and Fig.15 As shown, the air pump inkjet device 2 includes: a second shell 2-1, which is a two-half structure in the shape of a gun; a second extrusion mechanism 2-2, which is horizontally fixedly arranged in the second shell 2-1; a second front cover assembly 2-6, which is openably arranged at the front end of the second shell 2-1; a second syringe 2-3, which is threadedly connected to the second front cover assembly 2-6; an air pump 2-4, which is fixedly arranged at the handle position of the second shell 2-1; an air storage tank 2-5, which is arranged at the lower part of the front part of the second shell 2-1 and is fixedly connected to the second shell 2-1; a front cover release mechanism 2-7, which is inserted into the second shell 2-1 and slides in the second shell 2-1 to lock and release the second front cover assembly 2-6; a second trigger assembly 2-8, which is rotatably arranged on the second shell 2-1, and is used to trigger the air pump 2-4 and / or the second extrusion mechanism 2-2; a second display screen 2-9, which is clamped on the rear end of the second shell 2-1, and is used to set the parameters of the extrusion program and air pressure.

[0112] Among them, the nozzle 2-10 for the air pump type inkjet device is arranged at the outlet end of the second shell 2-1.

[0113] In the above embodiment, preferably, Fig.16 and Fig.17As shown, the second extrusion mechanism 2-2 includes: a second extrusion base 2-201; a second micro-stepping screw motor 2-202, fixedly arranged on the second extrusion base 2-201; a second slider 2-204, threadedly connected to the screw of the second micro-stepping screw motor 2-202, and capable of sliding under the drive of the screw of the second micro-stepping screw motor 2-202; a light hole is arranged on the second slider 2-204; an extrusion optical axis 2-203, arranged parallel to the screw of the second micro-stepping screw motor 2-202, and fixedly installed on the second extrusion base 2-201; the extrusion optical axis 2-203 passes through the light hole of the second slider 2-204; a second driving circuit board 2-205, fixedly arranged on the At the bottom of the second extrusion base 2-201, a touch switch 2-2053 is arranged on the second driving circuit board 2-205, and the touch switch 2-2053 is used to trigger the second extrusion mechanism 202 to work; the cover plate 2-206 is fixedly arranged on the top of the second extrusion base 2-201, and the two sides of the cover plate 2-206 are connected to the second shell 2-1, and the cover plate 2-206 is provided with a slot; the second sample needle seat 2-207 is fixedly connected to the second slider 2-204, and the second sample needle seat 2-207 is used to lock the piston rod of the second syringe 2-3, and drive the piston rod of the second syringe 2-3 to reciprocate under the action of the second micro stepping screw motor 2-202 and the second slider 2-204.

[0114] In the above embodiment, preferably, a second photoelectric sensor 2-2051 and an air pressure sensor 2-2052 are also provided on the second driving circuit board 2-205; the second photoelectric sensor 2-2051 is used to detect the original position and maximum stroke of the second slider 2-204; the air pressure sensor 2-2052 is used to connect with the inner cavity of the air tank 2-5 through the second air tank connector 2-505 to detect the air pressure in the air tank 2-5.

[0115] In the above embodiment, preferably, Fig.19 and Fig. 20As shown, the second front cover assembly 2-6 includes a second front cover 2-601, a mixing block 2-602, a second front cover joint 2-603 and a second front cover rotating shaft 2-604; the mixing block 2-602 is arranged on the second front cover 2-601, and a Y-shaped channel is arranged in the mixing block 2-602; one end of the second front cover joint 2-603 is respectively connected to the interface of a channel at the lower end of the mixing block 2-602, and the other end of the second front cover joint 2-603 is used to connect with the third air tank joint 2-506 through an air pipe to connect compressed air to the mixing block 2-602; the second front cover 2-601 is connected to the second shell 2-1 through the second front cover rotating shaft 2-604, so that the second front cover 2-601 can rotate around the second front cover rotating shaft 2-604.

[0116] In the above embodiment, preferably, Fig.18 As shown, the gas tank 2-5 includes a gas tank shell 2-501, a battery assembly 2-502, a power management board 2-503, a first gas tank connector 2-504, a second gas tank connector 2-505, a third gas tank connector 2-506, a one-way solenoid valve 2-507 and a connector 2-508; the gas tank shell 2-501 is a shell structure with a built-in hollow sealed cavity; one end of the first gas tank connector 2-504 is connected to the sealed cavity, and the other end thereof is connected to the air pump 2-4 through an air pipe to form an inflation circuit; one end of the second gas tank connector 2-505 is connected to the sealed cavity, and the other end thereof is connected to the air pressure sensor 2-2052 through an air pipe to form an air pressure detection circuit; the third gas tank connector 2-506 One end is connected to the sealed cavity, and the other end is connected to the inlet of the one-way solenoid valve 2-507 through the air pipe, and the outlet of the one-way solenoid valve 2-507 is connected to the second front cover joint 2-603; the battery assembly 2-502 is fixedly arranged at the bottom of the gas tank shell 2-501 to power the electrical components of the spraying device; the power management board 2-503 is fixedly arranged at the bottom of the gas tank shell 2-501 to provide power management for the spraying device; the connector 2-508 is electrically connected to the power management board 2-503, and the connector 2-508 is electrically connected to the electrical components of the second extrusion mechanism 2-2 and the air pump 2-4 to power the electrical components of the second extrusion mechanism 2-2 and the air pump 2-4;

[0117] The power management board 2-503 is provided with a power switch 2-5031, a charging interface 2-5032 and a charging indicator light 2-5033. The power switch 2-5031 is used to control the on and off of the power of the whole machine, the charging interface 2-5032 is used to charge the battery assembly, and the charging indicator light 2-5033 is used to display the charging status.

[0118] In the above embodiment, preferably, Fig.19 , Fig.21 and Fig. 22 As shown, the front cover release mechanism 2-7 includes: a front cover release lever 2-701, a release optical axis 2-702 and a compression spring 2-703; the bottom of the mixing block 2-602 has at least two protrusions, and the protrusions have an inverted slope;

[0119] The front cover release rod 2-701 has at least two hook-shaped structures, and the inner side of the hook-shaped structure has an inverted inclined surface corresponding to the protrusion; one end of the release optical axis 2-702 passes through the bottom of the front cover release rod 2-701 and is fixed to the front cover release rod 2-701; the other end of the release optical axis 2-702 is fixed to the second shell 2-1; the compression spring 2-703 is sleeved on the release optical axis 2-702.

[0120] It should be noted that when the compression spring is extended, the hook-shaped structure of the front cover release lever abuts against the protrusion of the mixing block to lock the mixing block. When unlocking is required, the front cover release lever is pressed to compress the spring and disengage the hook-shaped structure from the protrusion.

[0121] In the above embodiment, preferably, Fig.23 and Fig.24 As shown, the second sample needle seat 2-207 includes a second sample needle seat base 2-2071, a second sample needle cover 2-2072 and a second sample needle seat rotating shaft 2-2073; the second sample needle cover 2-2072 is connected to the second sample needle seat base 2-2071 through the second sample needle seat rotating shaft 2-2073, so that the second sample needle cover 2-2072 can be openably arranged on the second sample needle seat base 2-2071, and when the second sample needle cover 2-2072 is closed, the piston rod of the second syringe 2-3 is locked by the second sample needle cover 2-2072 and the second sample needle seat base 2-2071.

[0122] In the above embodiment, preferably, the second trigger assembly 2-8 includes a second trigger 2-801, a firing pin 2-802, a second trigger optical axis 2-803 and a second torsion spring 2-804; one end of the second trigger optical axis 2-803 is fixed to the second housing 2-1, and the other end passes through the second trigger 2-801, so that the second trigger 2-801 can rotate around the second trigger optical axis 2-803; the firing pin 2-802 is arranged on the top of the second trigger 2-801, and is used to strike the touch switch 2-2053 on the second driving circuit board 2-205; the second torsion spring 2-804 is mounted on the second trigger optical axis 2-803, one end of which is fixed to the second housing 2-1, and the other end is fixed to the second trigger 2-801, so as to provide power for resetting the second trigger 2-801.

[0123] In the above embodiment, preferably, the nozzle for the fan-type inkjet device includes a first internal mixing nozzle and a first external mixing nozzle; the nozzle for the air pump-type inkjet device includes a second internal mixing nozzle and a second external mixing nozzle.

[0124] In the above embodiment, preferably, Fig.26 As shown, the first external mixing nozzle includes a first nozzle body and a first pipe for reagent circulation, the first nozzle body is provided with a first gas channel that tapers from the back to the front; the first pipe is used to be plugged or integrally formed at the front end of the gas generating assembly, and the first pipe is used to be connected to the liquid connecting joint; the first pipe passes through the first gas channel and extends out of the front end face of the first gas channel by a preset distance;

[0125] like Fig. 27 As shown, the first internal mixing nozzle includes a second nozzle body and a second pipe for reagent circulation, and a second gas channel that tapers from back to front is provided in the second nozzle body; the second pipe is used to be plugged into or integrally formed at the front end of the gas generating assembly, and the second pipe is used to be connected to the liquid connecting joint; the second pipe extends into the second gas channel and is at a preset distance from the front end surface of the second gas channel; Fig.28 As shown, the second external mixing nozzle includes a third nozzle body, a first reagent channel for reagent circulation is provided at the center of the third nozzle body, a third gas channel for gas circulation is provided at the periphery of the first reagent channel, and the first reagent channel and the third gas channel respectively penetrate the third nozzle body, so that the gas and the reagent are mixed outside the third nozzle body;

[0126] like Fig.29As shown, the second internal mixing blower includes a fourth nozzle body, a second reagent channel for reagent circulation is arranged at the center of the fourth nozzle body, a fourth gas channel for gas circulation is arranged at the periphery of the second reagent channel, and the second reagent channel is connected with the fourth gas channel inside the fourth nozzle body to mix the gas and the reagent inside the fourth nozzle body.

[0127] In addition, the nozzle parameters can be set using the following formula:

[0128] External-mix nozzles for air-pump inkjet equipment:

[0129]

[0130] D mm is the average droplet diameter; M L is the liquid mass flow rate; M a is the gas mass flow rate; μ a is the gas viscosity; G a is the gas mass flow rate; d 1 is the outer diameter of the liquid nozzle.

[0131] Internal mixing nozzles for air pump inkjet equipment:

[0132]

[0133] D mm is the average droplet diameter; V r is the relative velocity between air and liquid; σ is the surface tension of liquid; ρ 1 is the liquid density; η is the liquid dynamic viscosity; Q 1 is the liquid volume flow rate; Q a is the gas volume flow rate.

[0134] Nozzles for blower inkjet equipment:

[0135]

[0136] Dmm is the average droplet diameter; C1, C2 are fitting coefficients; Vr is the relative velocity between air and liquid; σ is the surface tension of the liquid; ρ1 is the liquid density; ν1 is the kinematic viscosity of the liquid; Q1 is the liquid mass flow rate; ρa is the gas density; Qa is the liquid mass flow rate.

[0137] Among them, the air pump nozzle size examples are as follows:

[0138]

[0139] In addition, it should be noted that the fan nozzle: gas outlet diameter 3-8mm, liquid pipe diameter: outer diameter 1.5-3mm, inner diameter 0.5-2mm, pipe thickness less than or equal to 0.5mm;

[0140] Air pump nozzle: The outer diameter of the liquid in the air pump nozzle can be 1-6mm, the outer diameter of the gas can be 3-8mm, and the wall thickness is less than or equal to 0.5mm.

[0141] When the air pump inkjet device is working, key parameters such as extrusion and air pressure are set through the second display screen 2-9. After the setting is completed, the air pump 2-4 starts to work and inflates the sealed cavity of the air tank 2-5 through the air pipe. The air tank 2-5 is provided with an air pressure detection circuit. When the pressure in the air tank 2-5 reaches the set value, the extrusion function will be allowed. At this time, the second trigger 2-801 is pulled, and the one-way solenoid valve in the air tank 2-5 is opened. The air tank 2-5 outputs compressed gas to the outside. At the same time, the second extrusion mechanism 2-2 starts to work. According to the parameters set on the second display screen 2-9, driven by the second micro-stepping screw motor 2-202, the second sample needle seat 2-207 starts to move from right to left, driving the piston rod of the second syringe 2-3 to move, thereby completing the extrusion action. The liquid squeezed out of the second syringe 2-3 and the compressed gas output by the air tank 2-5 converge in the mixing block 2-602, and are finally sprayed out through the external mixing nozzle 2-10.

[0142] In addition, it should be noted that Fig.31 As shown, the number of the first syringe and the second syringe of the utility model can be one or more, and the number of the corresponding first extrusion mechanism and the second extrusion mechanism can also be one or more.

[0143] Embodiment 1:

[0144] like Fig.30 As shown, the spray pressure, extrusion speed, and nozzle size of the air pump inkjet device were tested respectively. The results showed that at the same extrusion speed and spray pressure, the smaller the nozzle diameter, the smaller the spray droplet size. At the same nozzle diameter and spray pressure, the greater the extrusion speed, the smaller the droplet size. At the same nozzle diameter and extrusion speed, the greater the spray pressure, the smaller the droplet size. The viscosity range of the material that the device can spray was tested. The results showed that materials with a viscosity of 1-10000mPa·s can be sprayed through this device. The cell viability after spraying was tested. The results showed that the cells still maintained a high viability of more than 90% after spraying, and the cell distribution after spraying was more uniform compared to injection.

[0145] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the utility model, rather than to limit it. Although the utility model has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the various embodiments of the utility model.

Claims

1. A spraying device for spraying a spray onto the skin, characterized in that: It comprises an inkjet device and a nozzle, wherein the nozzle is arranged at the outlet of the inkjet device; The inkjet device is used to extrude the material of the spray; The nozzle is used to spray the extruded material onto the skin in the form of a spray; The nozzle is a second internal mixing nozzle or a second external mixing nozzle; The second external mixing nozzle comprises a third nozzle body, wherein a first reagent channel for reagent circulation is provided at the center of the third nozzle body, a third gas channel for gas circulation is provided at the periphery of the first reagent channel, and the first reagent channel and the third gas channel respectively penetrate the third nozzle body, so that the gas and the reagent are mixed outside the third nozzle body; The second internal mixing nozzle includes a fourth nozzle body, a second reagent channel for reagent circulation is arranged at the center of the fourth nozzle body, a fourth gas channel for gas circulation is arranged on the periphery of the second reagent channel, and the second reagent channel is connected with the fourth gas channel inside the fourth nozzle body to mix the gas and the reagent inside the fourth nozzle body.

2. The spraying device according to claim 1, characterized in that The inkjet device is an air pump type inkjet device; The air pump type inkjet device comprises: The second shell is in the shape of two halves of a gun; A second extruding mechanism, horizontally and fixedly disposed in the second housing; A second front cover assembly, openably disposed at the front end of the second housing; a second syringe, threadedly connected to the second front cover assembly; An air pump is fixedly arranged at the handle position of the second housing; A gas storage tank, disposed below the front portion of the second shell and fixedly connected to the second shell; A front cover release mechanism, inserted into the second housing and sliding in the second housing to lock and release the second front cover assembly; A second trigger assembly is rotatably disposed on the second housing and is used to trigger the air pump and / or the second extrusion mechanism; The second display screen is connected to the rear end of the second shell and is used to set the parameters of the extrusion program and air pressure.

3. The spraying device according to claim 2, characterized in that: The second extrusion mechanism comprises: A second extrusion base; A second micro-stepping screw motor is fixedly arranged on the second extrusion base; The second slider is threadedly connected to the screw of the second micro-stepping screw motor and can slide under the drive of the screw of the second micro-stepping screw motor; the second slider is provided with a light hole; The extrusion optical axis is arranged parallel to the screw of the second micro-stepping screw motor and is fixedly mounted on the second extrusion base; the extrusion optical axis passes through the optical hole of the second slider; A second driving circuit board is fixedly arranged at the bottom of the second extrusion base, and a touch switch is arranged on the second driving circuit board, and the touch switch is used to trigger the second extrusion mechanism to work; A cover plate, fixedly arranged on the top of the second extrusion base, two sides of the cover plate are connected to the second shell, and the cover plate is provided with slots; The second sample needle seat is fixedly connected to the second slider, and is used to lock the piston rod of the second syringe and drive the piston rod of the second syringe to reciprocate under the action of the second micro-stepping screw motor and the second slider.

4. The spraying device according to claim 3, characterized in that: The second driving circuit board is also provided with a second photoelectric sensor and an air pressure sensor; The second photoelectric sensor is used to detect the home position and maximum stroke of the second slider; The air pressure sensor is used to communicate with the inner cavity of the air storage tank through the second air storage tank joint to detect the air pressure in the air storage tank.

5. The spraying device according to claim 4, characterized in that The second front cover assembly includes a second front cover, a flow mixing block, a second front cover joint and a second front cover rotating shaft; The mixing block is arranged on the second front cover, and a Y-shaped channel is arranged in the mixing block; One end of the second front cover joint is respectively connected to an interface of a channel at the lower end of the mixing block, and the other end of the second front cover joint is used to connect to the third air tank joint through an air pipe to connect compressed air to the mixing block; The second front cover is connected to the second housing via a second front cover rotation shaft, so that the second front cover can rotate around the second front cover rotation shaft.

6. The spraying device according to claim 5, characterized in that The gas tank comprises a gas tank shell, a battery assembly, a power management board, a first gas tank connector, a second gas tank connector, a third gas tank connector, a one-way solenoid valve and a connector; The gas storage tank shell is a shell structure with a built-in hollow sealed cavity; One end of the first gas storage tank joint is connected to the sealed cavity, and the other end thereof is connected to the air pump through an air pipe to form an inflation circuit; One end of the second gas storage tank connector is connected to the sealed cavity, and the other end thereof is connected to the air pressure sensor through an air pipe to form an air pressure detection circuit; One end of the third gas tank connector is connected to the sealed cavity, and the other end is connected to the inlet of the one-way solenoid valve through an air pipe, and the outlet of the one-way solenoid valve is connected to the second front cover connector; The battery assembly is fixedly arranged at the bottom of the gas storage tank shell to supply power to the electrical components of the whole machine; The power management board is fixedly arranged at the bottom of the gas storage tank shell to provide power management for the whole machine; The connector is electrically connected to the power management board, and the connector is electrically connected to the electrical components of the second extrusion mechanism and the air pump to supply power for the electrical connection between the second extrusion mechanism and the air pump.

7. The spraying device according to claim 5, characterized in that The front cover release mechanism comprises: a front cover release lever, a release optical axis and a compression spring; The bottom of the mixing block has at least two protrusions, and the protrusions have inverted slopes; The front cover release lever has at least two hook-shaped structures, and the inner side of the hook-shaped structure has an inverted slope corresponding to the protrusion; One end of the release optical axis passes through the bottom of the front cover release rod and is fixed to the front cover release rod; The other end of the release optical axis is fixed to the second housing; The compression spring is sleeved on the release optical axis.

8. The spraying device according to claim 3, characterized in that: The second sample needle seat comprises a second sample needle seat base, a second sample needle cover, and a second sample needle seat rotating shaft; The second sample needle cover is connected to the second sample needle seat base via a second sample needle seat rotating shaft so that the second sample needle cover can be openably arranged on the second sample needle seat base. When the second sample needle cover is closed, the piston rod of the second syringe is locked by the second sample needle cover and the second sample needle seat base.

9. The spraying device according to claim 3, characterized in that: The second trigger assembly includes a second trigger, a firing pin, a second trigger optical axis and a second torsion spring; One end of the second trigger optical axis is fixed to the second housing, and the other end passes through the second trigger, so that the second trigger can rotate around the second trigger optical axis; The firing pin is arranged on the top of the second trigger and is used to strike the touch switch on the second driving circuit board; The second torsion spring is sleeved on the second trigger optical axis, one end of the second torsion spring is fixed to the second housing, and the other end is fixed to the second trigger to provide power for resetting the second trigger.

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