Hemoglobin and helicobacter pylori antigen combined detection kit

Abstract

The utility model discloses a joint detection kit for hemoglobin and helicobacter pylori antigen, which comprises a dilution assembly filled with diluent, a sampling assembly used for collecting samples is arranged in the dilution assembly, a sealing assembly used for sealing connection is arranged between the dilution assembly and the sampling assembly, and the dilution assembly is connected with the sampling assembly. A detection assembly for detecting the concentration of hemoglobin and helicobacter pylori in a sample is arranged on the dilution assembly, and a limiting assembly capable of blocking the sealing assembly is further arranged on the dilution assembly; the limiting assembly is additionally arranged on the dilution assembly, so that when the sampling assembly samples and is placed in the inner cavity of the dilution assembly for dilution, the limiting assembly can stop the sealing assembly, and the situation that the bottom end of the sampling assembly penetrates into the inner cavity of the detection assembly in advance due to excessive rotation of the sealing assembly is effectively avoided; the sample dilution effect of the dilution assembly can be guaranteed, and the concentration detection effect of the detection assembly on hemoglobin and helicobacter pylori can also be guaranteed.

Description

Technical Field

[0001] The utility model relates to the technical field of digestive tract bleeding assessment, in particular to a hemoglobin and gastric Helicobacter pylori antigen combined detection kit. Background Art

[0002] Hemoglobin is an important marker for upper and lower gastrointestinal bleeding diseases and an important indicator for early screening of gastrointestinal malignancies. Helicobacter pylori is a major risk factor for gastric cancer. Therefore, the combined detection of Helicobacter pylori, hemoglobin and transferrin can help clinicians detect the patient's condition in time and intervene in treatment, which can greatly save medical resources and reduce the patient's pain and economic burden.

[0003] The existing patent document with announcement number CN107328927B discloses a combined detection kit for Helicobacter pylori and gastrointestinal bleeding and a method of use. The kit completes sample collection, dilution and detection in one step in a closed device. After sampling, a sample is fully diluted by the diluent in the device. In one step, the diluted sample enters the reaction area to complete the sample detection. The device has the characteristics of simple, safe, and fast operation, and is suitable for on-site use in homes, hospitals, etc., which greatly reduces work intensity and reduces potential infection risks.

[0004] Although the above-mentioned Helicobacter pylori and gastrointestinal bleeding combined detection kit and use method can solve the corresponding technical problems, the sampling cover and the dilution chamber are directly connected through two sections of threads of the connecting part. However, when the sampling cover is connected to the first section of the connecting part for sample dilution, the second section of the thread is not restricted, resulting in the sampling cover being easily rotated excessively, causing the end of the sampling tube to directly penetrate the diaphragm in advance, thereby causing a certain impact on the detection effect of the sample. For this reason, we propose a hemoglobin and Helicobacter pylori antigen combined detection kit. Utility Model Content

[0005] The utility model aims to provide a hemoglobin and gastric Helicobacter pylori antigen combined detection kit for solving the problems raised by the above-mentioned background technology.

[0006] In order to achieve the above-mentioned purpose, the main technical solutions adopted by the utility model include:

[0007] A combined detection kit for hemoglobin and gastric Helicobacter pylori antigen, comprising:

[0008] A dilution component filled with a diluent, wherein a sampling component for collecting samples is provided, a sealing component for sealing connection is provided between the dilution component and the sampling component, a detection component for detecting the concentration of hemoglobin and Helicobacter pylori in the sample is provided on the dilution component, and a limiting component capable of blocking the sealing component is also provided on the dilution component, and the limiting component is located at the bottom of the sealing component;

[0009] Among them, the limiting component includes a buckle that is movably mounted on the surface of the dilution component and has an arc-shaped structure. Both ends of the buckle are integrally formed with an inclined plate, an opening for taking and placing is formed between the two inclined plates, and a convex column is integrally formed on the side of the inclined plate away from the buckle.

[0010] As a preferred technical solution, a second handle is integrally formed on the outer surface of the buckle and at the center of the corresponding opening, and the two protruding columns are symmetrically arranged with respect to the second handle.

[0011] As a preferred technical solution, the dilution component includes a connecting tube movably penetrating the inner cavity of the buckle, the bottom of the connecting tube is connected to the dilution tube, the top and bottom of the connecting tube and the dilution tube are open, the diameter of the top of the inner cavity of the dilution tube is larger than the diameter of the bottom, a dilution cavity for containing diluent is formed between the connecting tube and the inner cavity of the dilution tube, and a diaphragm is fixedly connected to the bottom of the inner cavity of the dilution tube.

[0012] As a preferred technical solution, a convex ring is integrally formed on the lower portion of the outer surface of the connecting pipe.

[0013] As a preferred technical solution, the sampling assembly includes a sampling rod vertically placed in the dilution chamber, the bottom of the sampling rod is fixedly connected to a puncture cone, the puncture cone is located above the diaphragm, and the distance between the puncture cone and the diaphragm is smaller than the height of the buckle.

[0014] As a preferred technical solution, the sealing assembly includes a sealing cover threadedly connected to the upper surface of the connecting tube, the top of the inner cavity of the sealing cover is fixedly connected to the top of the sampling rod, and the first handles are fixedly connected to both sides of the outer surface of the sealing cover.

[0015] As a preferred technical solution, the detection assembly includes a detection tube threadedly connected to the lower part of the surface of the connecting tube, the inner cavity of the detection tube is vertically detachably connected with a plurality of equidistantly distributed test strips, and the bottom of the dilution tube penetrates to the lower part of the inner cavity of the detection tube;

[0016] Wherein, the test strips include hemoglobin test strips and Helicobacter pylori test strips.

[0017] As a preferred technical solution, a dovetail tenon is fixedly connected to the PVC bottom plate of the test strip, and a dovetail groove matching the dovetail tenon is provided on the inner wall surface of the detection tube.

[0018] As a preferred technical solution, a pressure ring is integrally formed at the bottom of the connecting tube, the outer surface of the pressure ring contacts the inner wall surface of the detection tube, and the bottom end of the pressure ring contacts the top of the dovetail tenon.

[0019] The utility model has at least the following beneficial effects:

[0020] The beneficial effect of the utility model of the present application is that by adding a limiting component to the dilution component, when the sampling component takes a sample and is placed in the inner cavity of the dilution component for dilution, the limiting component can block the sealing component, effectively preventing the bottom end of the sampling component from prematurely penetrating into the inner cavity of the detection component due to excessive rotation of the sealing component, which can not only ensure the dilution effect of the dilution component on the sample, but also ensure the detection effect of the detection component on the concentration of hemoglobin and Helicobacter pylori; during detection, it is only necessary to remove the limiting component from the dilution component and continue to rotate the sealing component to perform hemoglobin and Helicobacter pylori concentration detection, which is very convenient. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 This is a schematic diagram of the structure of a hemoglobin and gastric Helicobacter pylori antigen combined detection kit of the utility model;

[0022] Figure 2 It is a schematic diagram of the structure of a hemoglobin and gastric Helicobacter pylori antigen combined detection kit of the utility model;

[0023] Figure 3 It is a schematic diagram of the three-dimensional cutaway structure of the dilution component and the detection component of a combined detection kit for hemoglobin and gastric Helicobacter pylori antigen of the utility model;

[0024] Figure 4 The utility model is a schematic diagram of a three-dimensional exploded structure of a detection component of a hemoglobin and gastric Helicobacter pylori antigen combined detection kit.

[0025] In the figure: 1. dilution assembly; 11. connecting tube; 111. convex ring; 112. pressure ring; 12. dilution tube; 13. dilution chamber; 14. diaphragm; 2. sampling assembly; 21. sampling rod; 22. puncture cone; 3. sealing assembly; 31. sealing cover; 32. first handle; 4. detection assembly; 41. detection tube; 411. dovetail groove; 42. test strip; 421. dovetail tenon; 5. limit assembly; 51. buckle; 52. inclined plate; 53. convex column; 54. second handle. DETAILED DESCRIPTION

[0026] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0027] See also Figure 1-Figure 4 The embodiment of the utility model provides a hemoglobin and gastric Helicobacter pylori antigen combined detection kit, comprising: a dilution component 1 filled with a diluent, a sampling component 2 for collecting a sample, a sealing component 3 for sealing connection, a detection component 4 for detecting the concentration of hemoglobin and gastric Helicobacter pylori in the sample, and a limit component 5 that can block the sealing component 3; the sampling component 2 is arranged in the inner cavity of the dilution component 1, the sealing component 3 is arranged between the dilution component 1 and the sampling component 2, the detection component 4 and the limit component 5 are both arranged on the dilution component 1, and the limit component 5 is located at the bottom of the sealing component 3; the limit component 5 includes a buckle 51 that is movably sleeved on the surface of the dilution component 1 and has an arc-shaped structure, both ends of the buckle 51 are integrally formed with an inclined plate 52, an opening for taking and placing is formed between the two inclined plates 52, and a convex column 53 is integrally formed on the side of the inclined plate 52 away from the buckle 51, and the spacing between the two convex columns 53 is smaller than the spacing between the two ends of the buckle 51. The convex column 53 can avoid the phenomenon of stress concentration on the inclined plate 52.

[0028] Among them, a second handle 54 is integrally formed on the outer surface of the buckle 51 and at the center of the corresponding opening, and the two protrusions 53 are symmetrically arranged about the second handle 54. The second handle 54 can increase the contact area with the buckle 51, making it convenient to take and place the buckle 51.

[0029] Among them, the dilution component 1 includes a connecting tube 11 movably penetrating the inner cavity of the buckle 51, the bottom of the connecting tube 11 is connected to the dilution tube 12, the top and bottom of the connecting tube 11 and the dilution tube 12 are open, the diameter of the top of the inner cavity of the dilution tube 12 is larger than the diameter of the bottom, and a dilution cavity 13 for containing a diluent is formed between the connecting tube 11 and the inner cavity of the dilution tube 12, and a diaphragm 14 is fixedly connected to the bottom of the inner cavity of the dilution tube 12.

[0030] A convex ring 111 is integrally formed at the lower portion of the outer surface of the connecting tube 11 , and the convex ring 111 can be used to facilitate handholding of the connecting tube 11 .

[0031] Among them, the sampling component 2 includes a sampling rod 21 placed vertically in the inner cavity of the dilution chamber 13, and a puncture cone 22 is fixedly connected to the bottom of the sampling rod 21. The puncture cone 22 is located above the diaphragm 14, and the distance between the puncture cone 22 and the diaphragm 14 is smaller than the height of the buckle 51, so that after the buckle 51 is removed, the rotating sealing component 3 can drive the puncture cone 22 to move downward and puncture the diaphragm 14, so that the diluent can flow to the inner cavity of the detection component 4 for detection operation.

[0032] Among them, the sealing assembly 3 includes a sealing cover 31 threadedly connected to the upper surface of the connecting tube 11. The sealing cover 31 can seal the dilution chamber 13 to reduce or eliminate the risk of leakage. The top of the inner cavity of the sealing cover 31 is fixedly connected to the top of the sampling rod 21. Both sides of the outer surface of the sealing cover 31 are fixedly connected with a first handle 32. The first handle 32 can play an anti-slip role to facilitate the rotation of the sealing cover 31.

[0033] The detection assembly 4 includes a detection tube 41 threadedly connected to the lower part of the surface of the connecting tube 11. The detection tube is made of a transparent plastic material so that the situation inside the detection tube 41 can be observed. The inner cavity of the detection tube 41 is vertically detachably connected with a plurality of equidistantly distributed test strips 42. The bottom of the dilution tube 12 penetrates to the lower part of the inner cavity of the detection tube 41. The diaphragm 14 can reduce the falling height of the diluent, effectively avoiding the phenomenon that splashing of the diluent when it flows into the inner cavity of the detection tube 41 affects the detection effect of the test strips 42.

[0034] The test strips 42 include a hemoglobin test strip and a Helicobacter pylori test strip.

[0035] Among them, a dovetail tenon 421 is fixedly connected to the PVC bottom plate of the test strip 42, and a dovetail groove 411 compatible with the dovetail tenon 421 is opened on the inner wall surface of the detection tube 41. Through the coordinated use of the dovetail groove 411 and the dovetail tenon 421, a detachable connection between the detection tube 41 and the test strip 42 can be achieved, which is convenient for placing the test strip 42 in the corresponding inner cavity of the detection tube 41 according to actual use requirements.

[0036] Among them, a pressure ring 112 is integrally formed at the bottom of the connecting tube 11, the outer surface of the pressure ring 112 contacts the inner wall surface of the detection tube 41, and the bottom end of the pressure ring 112 contacts the top of the dovetail tenon 421. The pressure ring 112 can block the dovetail tenon 421, which helps to improve the stability of the dovetail tenon 421 when it is placed in the inner cavity of the dovetail groove 411.

[0037] The working principle of the utility model is:

[0038] S1. Sampling: The sealing cover 31 is rotated by the first handle 32 to separate the sealing cover 31 from the connecting tube 11, and the sealing cover 31 drives the sampling assembly 2 to move synchronously until the sampling assembly 2 moves out of the inner cavity of the dilution chamber 13, and sufficient samples are collected by the puncture cone 22;

[0039] S2. Dilute the sample: insert the sampling assembly 2 with the sample taken into the inner cavity of the dilution chamber 13, screw the sealing cover 31 onto the connecting tube 11, and shake the dilution assembly 1 to dilute the sample taken with the diluent in the dilution chamber 13;

[0040] S3. Detecting samples: Pull the buckle 51 with force through the second handle 54, so that the buckle 51 drives the inclined plate 52 and the protruding column 53 to move synchronously, and the inner wall surface of the buckle 51 is squeezed and deformed by the surface of the connecting tube 11, so that the opening gradually becomes larger, until the buckle 51 is separated from the connecting tube 11. At this time, the sealing cover 31 can be rotated continuously, so that the sealing cover 31 drives the sampling rod 21 and the puncture cone 22 to move downward and puncture the diaphragm 14, so that the diluted sample in the dilution chamber 13 flows into the inner cavity of the detection tube 41, and the sampling end of the test strip 42 absorbs the sample for detection, and finally the detection result of the test strip 42 can be observed.

[0041] Parts not involved in the present invention are the same as the prior art or can be implemented by the prior art. Although the embodiments of the present invention have been shown and described, it is understood by those skilled in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the present invention, and the scope of the present invention is defined by the attached claims and their equivalents.

Claims

1. A combined detection kit for hemoglobin and gastric Helicobacter pylori antigen, characterized in that: include: A dilution component (1) containing a diluent, wherein a sampling component (2) for collecting a sample is provided therein, a sealing component (3) for sealingly connecting the dilution component (1) and the sampling component (2), a detection component (4) for detecting the concentration of hemoglobin and Helicobacter pylori in the sample is provided on the dilution component (1), and a limiting component (5) capable of blocking the sealing component (3) is also provided on the dilution component (1), wherein the limiting component (5) is located at the bottom of the sealing component (3); The limiting component (5) comprises a buckle (51) movably sleeved on the surface of the dilution component (1) and having an arc-shaped structure, an inclined plate (52) is integrally formed at both ends of the buckle (51), an opening for taking and placing is formed between the two inclined plates (52), and a convex column (53) is integrally formed on a side of the inclined plate (52) away from the buckle (51).

2. A hemoglobin and gastric Helicobacter pylori antigen combined detection kit according to claim 1, characterized in that: A second handle (54) is integrally formed on the outer surface of the buckle (51) and at the center of the corresponding opening, and the two protruding columns (53) are symmetrically arranged with respect to the second handle (54).

3. A hemoglobin and gastric Helicobacter pylori antigen combined detection kit according to claim 1, characterized in that: The dilution assembly (1) comprises a connecting tube (11) movably penetrating the inner cavity of a buckle (51); the bottom of the connecting tube (11) is connected to a dilution tube (12); the top and bottom of the connecting tube (11) and the dilution tube (12) are both open; the diameter of the top of the inner cavity of the dilution tube (12) is greater than the diameter of the bottom; a dilution cavity (13) for containing a diluent is formed between the connecting tube (11) and the inner cavity of the dilution tube (12); and a diaphragm (14) is fixedly connected to the bottom of the inner cavity of the dilution tube (12).

4. A combined detection kit for hemoglobin and Helicobacter pylori antigen according to claim 3, characterized in that: A convex ring (111) is integrally formed at the lower portion of the outer surface of the connecting pipe (11).

5. A combined detection kit for hemoglobin and Helicobacter pylori antigen according to claim 3, characterized in that: The sampling assembly (2) comprises a sampling rod (21) vertically placed in the inner cavity of the dilution chamber (13), the bottom of the sampling rod (21) is fixedly connected with a puncture cone (22), the puncture cone (22) is located above the diaphragm (14), and the distance between the puncture cone (22) and the diaphragm (14) is less than the height of the buckle (51).

6. A hemoglobin and gastric Helicobacter pylori antigen combined detection kit according to claim 3, characterized in that: The sealing assembly (3) comprises a sealing cover (31) threadedly connected to the upper surface of the connecting tube (11), the top of the inner cavity of the sealing cover (31) is fixedly connected to the top end of the sampling rod (21), and the first handles (32) are fixedly connected to both sides of the outer surface of the sealing cover (31).

7. A combined detection kit for hemoglobin and Helicobacter pylori antigen according to claim 3, characterized in that: The detection assembly (4) comprises a detection tube (41) threadedly connected to the lower part of the surface of the connecting tube (11); the inner cavity of the detection tube (41) is vertically detachably connected to a plurality of equidistantly distributed test strips (42); and the bottom of the dilution tube (12) penetrates to the lower part of the inner cavity of the detection tube (41); Wherein, the test strips (42) include hemoglobin test strips and Helicobacter pylori test strips.

8. A hemoglobin and gastric Helicobacter pylori antigen combined detection kit according to claim 7, characterized in that: A dovetail tenon (421) is fixedly connected to the PVC bottom plate of the test strip (42), and a dovetail groove (411) matching the dovetail tenon (421) is formed on the inner wall surface of the detection tube (41).

9. A combined detection kit for hemoglobin and Helicobacter pylori antigen according to claim 8, characterized in that: A pressure ring (112) is integrally formed at the bottom of the connecting tube (11), the outer surface of the pressure ring (112) contacts the inner wall surface of the detection tube (41), and the bottom end of the pressure ring (112) contacts the top of the dovetail tenon (421).

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