Multimodal chemical experiment teaching device based on microfluidic chip

Abstract

The utility model belongs to the field of chemical experiments, particularly relates to a multi-mode chemical experiment teaching device based on a microfluid chip, and solves the problems of single function, complex operation and low cleaning efficiency in the prior art. The device comprises a shell, a cleaning bin, a supporting rod, a test plate, a chip substrate and a unit module thereof, an electric cylinder driving system and a rotating plate locking mechanism. Through modular design and automatic control, rapid switching of multiple experiment modes is achieved, and experiment flexibility and efficiency are remarkably improved. The cleaning bin is provided with an ultrasonic generator and a blow-off pipe, so that the experimental assembly is effectively cleaned; the chip substrate is detachably provided with a mixing unit, a reaction unit and a detection unit, so that maintenance is convenient; automatic operation is achieved through an electric cylinder driving and rotating plate locking mechanism. The device is suitable for the field of chemical experiment teaching, and has the characteristics of high efficiency, convenience and low cost.

Description

Technical Field

[0001] The utility model relates to the technical field of chemical experiment, in particular to a multi-modal chemical experiment teaching device based on a microfluidic chip. Background Art

[0002] In the field of chemical experiment teaching, the microfluidic chip technology has gradually become an important tool for research and teaching due to its characteristics of high efficiency, precision and miniaturization. The microfluidic chip can realize the rapid processing and analysis of trace samples, providing a new operation platform for chemical experiments. However, in actual teaching applications, the existing experimental devices based on microfluidic chips still have many deficiencies. First of all, traditional devices usually have a single function and are difficult to meet the needs of multi-modal experiments, restricting students' research and understanding of different reaction paths and experimental conditions. Secondly, the existing equipment is inconvenient for cleaning and maintenance, and it is easy to affect the accuracy of experimental results due to residues, while also increasing the operation complexity. In addition, some devices lack intelligent control means and cannot realize the automatic operation of the experimental process and the real-time collection and visualization of data, resulting in low teaching efficiency and difficult to stimulate students' learning interest.

[0003] More importantly, the experimental devices in the existing technology have obvious defects in modular design. When changing the experimental mode or adjusting the fluid path, it is often necessary to reassemble the entire system, which not only takes time and effort, but also may introduce human errors. At the same time, the treatment of waste liquid generated during the experiment by some devices is not perfect, which is easy to cause environmental pollution or safety hazards. These problems seriously restrict the wide application of microfluidic chip technology in chemical experiment teaching. Therefore, it is of great practical significance and application value to develop a chemical experiment teaching device integrating multi-modal experiments, convenient cleaning, intelligent control and environmental protection waste liquid treatment. Such a device can not only improve the flexibility and efficiency of experimental teaching, but also provide students with a more intuitive and comprehensive learning experience, thus promoting the innovation and development of chemical experiment teaching. Summary of the Utility Model

[0004] Aiming at the problems of single function, complex operation and low cleaning efficiency existing in the existing chemical experiment teaching devices, the utility model provides a multi-modal chemical experiment teaching device based on a microfluidic chip. Through modular design and automatic control, the device realizes the rapid switching of multiple experimental modes, significantly improving the flexibility and efficiency of chemical experiment teaching.

[0005] The utility model provides a multi-modal chemical experiment teaching device based on a microfluidic chip, which includes a housing, a cleaning system, a support and test platform, a chip substrate and its unit modules, an electric cylinder drive system, and a rotating plate locking mechanism. Among them: a cleaning chamber is provided inside the housing for cleaning the experimental components. A drain port is provided on the bottom wall of the cleaning chamber and is connected to a sewage discharge pipe through a flange. The sewage discharge pipe extends to the outside of the housing to discharge sewage; an ultrasonic generator is fixedly installed on one side of the cleaning chamber for efficiently cleaning the experimental components; an inner groove is also provided inside the housing, and part of the sewage discharge pipe is located in the inner groove, which is convenient for maintenance and management.

[0006] Further, symmetrically arranged support rods are fixed to the top of the housing by screws. The top of the support rods is fixedly connected together to a test plate, which is used to place the chip substrate and other experimental components to ensure the stability of the experimental operation.

[0007] The chip substrate is slidably installed in the cleaning chamber through a lifting rod and is detachably installed with a mixing unit, a reaction unit, and a detection unit. Among them, the mixing unit is provided with a sample injection end for the mixing operation of samples, and symmetrically arranged connection holes are provided on both sides for connecting with other modules; the reaction unit includes a reaction carrier on which three array-distributed modal replacement plates are slidably installed. Each modal replacement plate is designed with different fluid paths for students to study; both sides of the modal replacement plate are fixed with connecting plates through buckles, and the module-to-module quick connection and replacement are realized by driving beads with a second spring; the detection unit is installed with sensors, such as a pH fiber optic sensor, for collecting detection results and visualizing them.

[0008] Further, an electric cylinder is fixedly installed on the top of the reaction unit. The output end of the electric cylinder is fixedly connected to a telescopic rod, and the bottom end of the telescopic rod is fixedly connected to the uppermost modal replacement plate for driving the movement of the modal replacement plate to realize the switching of different experimental modes. In particular, a rotating plate is rotatably installed on the top of the reaction unit. A through hole is provided in the middle of the rotating plate for the electric cylinder to pass through; a clamping hole is provided on the rotating plate corresponding to a clamping rod; a fixing block is fixedly installed on the lower surface of the uppermost modal replacement plate by screws. A guide groove is provided inside the fixing block, and the clamping rod is slidably connected inside the guide groove. A limiting plate with an integrally formed structure is provided at the bottom end of the clamping rod, and a first spring is sleeved outside. The two ends are respectively fixed to the fixing block and the limiting plate through buckles, so as to realize the quick locking and unlocking between the rotating plate and the modal replacement plate.

[0009] Further, a control panel and a controller are fixedly installed on the front of the housing for controlling the operation of the entire device; the ultrasonic generator, the control panel, and the electric cylinder are all electrically connected to the controller to form a unified control system.

[0010] The technical solution of the present utility model is achieved in the following manner: S1: The implementation method of the cleaning system is to set an ultrasonic generator in the cleaning chamber. The ultrasonic generator generates a cavitation effect through high-frequency vibration to remove the residues on the surface of the experimental components. The drain outlet at the bottom wall of the cleaning chamber is connected to the sewage discharge pipe through a flange to discharge the cleaned sewage outside the housing, avoiding cross-contamination. Part of the sewage discharge pipe is located in the inner groove of the housing, facilitating maintenance and management. S2: The implementation method of the chip substrate and its unit modules is that the chip substrate is slidably installed in the cleaning chamber through a lifting rod. The lifting rod drives the chip substrate to move up and down, facilitating cleaning and operation. The mixing unit, reaction unit, and detection unit achieve rapid connection and replacement between modules through connection holes and beads, ensuring the convenience of modular design. S3: The implementation method of the electric cylinder drive system is that the output end of the electric cylinder is fixedly connected to a telescopic rod. The bottom end of the telescopic rod is fixedly connected to the uppermost modal replacement plate. By driving the electric cylinder to extend and retract through the controller, the modal replacement plate is driven to move up and down to achieve the switching of different experimental modes. The electric cylinder passes through the through hole in the middle of the rotating plate to ensure the stability of the movement process. S4: The implementation method of the rotating plate locking mechanism is that the card holes on the rotating plate correspond to the card rods. The card rods drive the limiting plate to move through the first spring to achieve rapid locking and unlocking between the rotating plate and the modal replacement plate. The guide groove inside the fixed block restricts the movement trajectory of the card rods to ensure the accuracy of the locking and unlocking actions.

[0011] The beneficial effects of the present utility model are embodied by the following technical means:

[0012] By designing different modal replacement plates, rapid switching of multiple experimental modes is achieved, meeting the diverse needs of chemistry experiment teaching; the chip substrate and the mixing unit, reaction unit, and detection unit thereon adopt a detachable design, facilitating assembly, cleaning, and maintenance; the cleaning chamber is equipped with an ultrasonic generator and a sewage discharge pipe, which can effectively clean the experimental components and reduce cross-contamination; through the electric cylinder drive and the rotating plate locking mechanism, automatic control of the experimental process is achieved, improving the experimental efficiency; the detection unit is equipped with sensors, which can collect experimental data in real time and present it in a visual form, facilitating students to understand and analyze.

[0013] In particular, through modular design and automatic control, the present utility model significantly improves the flexibility and efficiency of chemistry experiment teaching, while reducing the operation difficulty and maintenance cost, and is suitable for wide application in the field of chemistry experiment teaching.

[0014] To make the above and other purposes, features, and advantages of the present utility model more obvious and understandable, the following preferred embodiments are specifically given, and in conjunction with the accompanying drawings, the detailed description is as follows. Description of the Drawings

[0015] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the drawings in the following description are only some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can be obtained based on these drawings.

[0016] Figure 1 Schematic diagram of the overall structure of the present invention;

[0017] Figure 2 Schematic diagram of the structure for opening the inner groove in the present invention;

[0018] Figure 3 Schematic diagram of the structure of the present invention with the rotating plate removed;

[0019] Figure 4 Another perspective schematic diagram of the present invention with the rotating plate removed;

[0020] Figure 5 Enlarged view of the part marked A in the present invention;

[0021] Figure 6 Schematic diagram of the structure of the present invention with the chip substrate retracted;

[0022] Figure 7 Schematic diagram of the structure highlighting the inside of the cleaning chamber in the present invention;

[0023] Figure 8 Schematic diagram of the structure of the microfluidic chip in the present invention;

[0024] Figure 9 Cross-sectional view of the modal replacement plate in the present invention.

[0025] Reference numerals in the figure:

[0026] 1. Housing; 2. Control panel; 3. Controller; 4. Support rod; 5. Test plate; 6. Ultrasonic generator; 7. Cleaning chamber; 71. Drain port; 8. Chip substrate; 81. Mixing unit; 82. Reaction unit; 821. Reaction carrier; 822. Modal replacement plate; 823. Connecting plate; 824. Catching bead; 83. Detection unit; 84. Sampling end; 85. Sensor; 9. Rotating plate; 10. Sewage pipe; 11. Inner groove; 12. Fixed block; 13. First spring; 14. Limiting plate; 15. Clamping rod; 16. Clamping hole; 17. Electric cylinder; 18. Telescopic rod; 19. Lifting rod; 20. Groove; 21. Second spring. Detailed implementation manners

[0027] The utility model provides a multi-modal chemical experiment teaching device based on a microfluidic chip, which realizes the rapid switching of multiple experiment modes through modular design and automatic control, and significantly improves the flexibility and efficiency of chemical experiment teaching. The following will describe in detail the specific implementation manners of the utility model with reference to the accompanying drawings.

[0028] As Figures 1 to 9 shown, the device of the utility model includes a housing 1, a cleaning system, a support and test platform, a chip substrate 8 and its unit modules, an electric cylinder drive system, and a rotating plate locking mechanism. A cleaning chamber 7 is provided inside the housing 1 for cleaning the experimental components to reduce cross-contamination. A drain port 71 is provided on the bottom wall of the cleaning chamber 7 and is connected to a sewage discharge pipe 10 through a flange. The sewage discharge pipe 10 extends to the outside of the housing, facilitating the discharge of the cleaned sewage. Part of the sewage discharge pipe 10 is located in the inner groove 11 of the housing. The design of the inner groove 11 makes the sewage discharge pipe easy to maintain and manage. An ultrasonic generator 6 is fixedly installed on one side of the cleaning chamber 7. The ultrasonic generator 6 generates cavitation effects through high-frequency vibration to remove the residues on the surface of the experimental components, thereby improving the cleaning efficiency. A control panel 2 and a controller 3 are fixedly installed on the front part of the housing 1 for uniformly controlling the operation of the entire device. The ultrasonic generator 6, the control panel 2, and the electric cylinder 17 are all electrically connected to the controller 3 to form a complete control system. The operating principle of the cleaning system is as follows: When the experiment is completed, the chip substrate 8 and the mixing unit 81, reaction unit 82, and detection unit 83 thereon are driven by a lifting rod 19 into the cleaning chamber 7. After the ultrasonic generator 6 is started, it cleans the experimental components through high-frequency vibration. The cleaned sewage is discharged to the outside of the housing through the drain port 71 and the sewage discharge pipe 10.

[0029] At the top of the housing 1, symmetrically arranged support rods 4 are fixed by screws. At the top of the support rods 4, a test plate 5 is fixedly connected together. The test plate 5 is used to place the chip substrate 8 and other experimental components to ensure the stability of experimental operations. The chip substrate 8 is slidably installed in the cleaning chamber 7 through a lifting rod 19. The lifting rod 19 can drive the chip substrate 8 to move up and down, facilitating cleaning and operation. On the chip substrate 8, a mixing unit 81, a reaction unit 82, and a detection unit 83 are sequentially and detachably fixedly installed. The mixing unit 81 is provided with a sample injection end 84 for the mixing operation of samples. Symmetrically arranged connection holes are opened on both sides, facilitating connection with other modules. The detection unit 83 is equipped with a sensor 85, such as a pH fiber optic sensor, for collecting and visualizing detection results, facilitating students to observe experimental data in real time. The reaction unit 82 includes a reaction carrier 821. On the reaction carrier 821, three array-distributed modal replacement plates 822 are slidably installed. Each modal replacement plate 822 is designed with a different fluid path for students to study. On both sides of the modal replacement plate 822, a connecting plate 823 is fixed by a buckle, and a second spring 21 is used to drive a bead 824 to achieve quick connection and replacement between modules. The design of the bead 824 enables the modal replacement plate 822 to be quickly disassembled and replaced when needed, thus meeting the requirements of different experimental modes.

[0030] At the top of the reaction unit 82, a rotating plate 9 is rotatably installed. A through hole is opened in the middle of the rotating plate 9 for the cylinder 17 to pass through. The output end of the cylinder 17 is fixedly connected to a telescopic rod 18. The bottom end of the telescopic rod 18 is fixedly connected to the uppermost modal replacement plate 822, used to drive the movement of the modal replacement plate 822 to achieve the switching of different experimental modes. The cylinder 17 passes through the through hole in the middle of the rotating plate 9 to ensure the stability of the movement process. A clamping hole 16 is opened on the rotating plate 9, corresponding to the clamping rod 15. On the lower surface of the uppermost modal replacement plate 822, a fixing block 12 is fixed by screws. A guide groove is opened inside the fixing block 12, and the clamping rod 15 is slidably connected inside the guide groove. At the bottom end of the clamping rod 15, a limiting plate 14 with an integrally formed structure is provided, and a first spring 13 is sleeved outside. Both ends of the first spring 13 are fixedly connected to the fixing block 12 and the limiting plate 14 by buckles respectively, thus realizing the quick locking and unlocking between the rotating plate 9 and the modal replacement plate 822. The guide groove inside the fixing block 12 restricts the movement track of the clamping rod 15 to ensure the accuracy of the locking and unlocking actions. The operating principle of the rotating plate locking mechanism is as follows: When it is necessary to replace the modal replacement plate 822, the controller 3 drives the cylinder 17 to make the telescopic rod 18 drive the uppermost modal replacement plate 822 to move upward. At the same time, the first spring 13 drives the clamping rod 15 to disengage from the clamping hole 16, and the rotating plate 9 is unlocked. After the modal replacement plate 822 is replaced, the cylinder 17 drives the modal replacement plate 822 to move downward, and the first spring 13 drives the clamping rod 15 to re-insert into the clamping hole 16, and the rotating plate 9 is locked.

[0031] The operating principle of the electric cylinder drive system is as follows: The controller 3 issues instructions according to experimental requirements, driving the telescopic rod 18 inside the electric cylinder 17 to perform telescopic motion. The bottom end of the telescopic rod 18 is fixedly connected to the uppermost modal replacement plate 822, driving the modal replacement plate 822 to move up and down through the telescopic motion, thereby realizing the switching of different experimental modes. For example, in a certain experiment, if it is necessary to study the chemical reaction process under a specific fluid path, the controller 3 drives the electric cylinder 17 to move the corresponding modal replacement plate 822 to the working position and fixes its position through the locking mechanism of the rotating plate 9. After the experiment is completed, the electric cylinder 17 drives the modal replacement plate 822 to move again to replace other modal replacement plates 822 or perform cleaning operations.

[0032] The operation process of the technical solution of the present utility model in practical application is as follows: S1, inject the sample to be tested into the device through the sample injection end 84 of the mixing unit 81, and the sample enters the reaction unit 82 after preliminary mixing in the mixing unit 81. S2, the controller 3 selects an appropriate modal replacement plate 822 according to experimental requirements, drives the electric cylinder 17 to make the telescopic rod 18 drive the corresponding modal replacement plate 822 to move to the working position, and fixes its position through the locking mechanism of the rotating plate 9. S3, after the sample completes the chemical reaction in the selected modal replacement plate 822, it enters the detection unit 83. The sensor 85 in the detection unit 83 collects experimental data and visualizes it, facilitating students to observe the experimental results in real time. S4, after the experiment is completed, the controller 3 drives the lifting rod 19 to bring the chip substrate 8 and the mixing unit 81, reaction unit 82, and detection unit 83 thereon into the cleaning chamber 7. The ultrasonic generator 6 is started to clean the experimental components, and the sewage after cleaning is discharged to the outside of the housing through the drain port 71 through the sewage discharge pipe 10. S5, after the cleaning is completed, the lifting rod 19 brings the chip substrate 8 and the experimental components thereon back to the original position to prepare for the next experiment.

[0033] The present utility model realizes the rapid switching of multiple experimental modes by designing different modal replacement plates 822, meeting the diverse needs of chemistry experiment teaching. The chip substrate 8 and the mixing unit 81, reaction unit 82, and detection unit 83 thereon adopt a detachable design, facilitating assembly, cleaning, and maintenance. The cleaning chamber 7 is equipped with an ultrasonic generator 6 and a sewage discharge pipe 10, which can effectively clean the experimental components and reduce cross-contamination. The electric cylinder drive system and the rotating plate locking mechanism realize the automatic control of the experimental process and improve the experimental efficiency. The detection unit 83 is equipped with a sensor 85, which can collect experimental data in real time and present it in a visual form, facilitating students to understand and analyze. In particular, the present utility model significantly improves the flexibility and efficiency of chemistry experiment teaching through modular design and automatic control, while reducing the operation difficulty and maintenance cost, and is suitable for wide application in the field of chemistry experiment teaching.

[0034] The above are only the embodiments of the present utility model, and thus do not limit the patent scope of the present utility model. Any equivalent structure or equivalent process transformation made by using the content of the specification and drawings of the present utility model, or directly or indirectly applied in other related technical fields, shall be equally included in the patent protection scope of the present utility model.

Claims

1. A multimodal chemical experiment teaching device based on a microfluidic chip, characterized in that: The invention comprises a housing (1), a cleaning system, a support and test platform, a chip substrate (8) and its unit modules, an electric cylinder drive system and a rotating plate locking mechanism; a cleaning chamber (7) is provided inside the housing (1); a drainage port (71) is provided on the bottom wall of the cleaning chamber (7) and is connected to a drainage pipe (10) via a flange; an ultrasonic generator (6) is fixedly installed on one side of the cleaning chamber (7); symmetrically arranged support rods (4) are fixedly installed on the top of the housing (1) via screws; the tops of the support rods (4) are fixedly connected to a test plate (5); the chip substrate (8) is slidably installed in the cleaning chamber (7) via a lifting rod (19) and can be The mixing unit (81), the reaction unit (82) and the detection unit (83) are detachably installed; an electric cylinder (17) is fixedly installed on the top of the reaction unit (82); the output end of the electric cylinder (17) is fixedly connected to the telescopic rod (18); the bottom end of the telescopic rod (18) is fixedly connected to the uppermost mode replacement plate (822); a rotating plate (9) is rotatably installed on the top of the reaction unit (82); a through hole is provided in the middle of the rotating plate (9) for the electric cylinder (17) to pass through; a clamping hole (16) is provided on the rotating plate (9) and corresponds to the clamping rod (15); and a control panel (2) and a controller (3) are fixedly installed on the front of the housing (1).

2. The multimodal chemical experiment teaching device based on a microfluidic chip according to claim 1, characterized in that: The drainage port (71) on the bottom wall of the cleaning bin (7) is connected to a drainage pipe (10) via a flange. The drainage pipe (10) extends to the outside of the shell, and part of the drainage pipe (10) is located in the inner groove (11) of the shell.

3. The multimodal chemical experiment teaching device based on microfluidic chip according to claim 1, characterized in that: An ultrasonic generator (6) is fixedly mounted on one side of the cleaning chamber (7) for cleaning residues on the surface of the experimental components.

4. The multimodal chemical experiment teaching device based on a microfluidic chip according to claim 1, characterized in that: The mixing unit (81) on the chip substrate (8) is provided with an injection end (84) and symmetrically arranged connection holes on both sides. The reaction unit (82) comprises a reaction carrier (821) on which three array-distributed mode replacement plates (822) are slidably mounted.

5. The multimodal chemical experiment teaching device based on microfluidic chip according to claim 1, characterized in that: The two sides of the mode replacement plate (822) are fixed with connecting plates (823) by means of buckles, and the second spring (21) drives the clamping beads (824) to achieve rapid connection and replacement between modules.

6. The multimodal chemical experiment teaching device based on microfluidic chip according to claim 1, characterized in that: A fixing block (12) is fixed to the lower surface of the rotating plate (9) by screws, a guide groove is provided inside the fixing block (12), a clamping rod (15) is slidably connected inside the guide groove, a limiting plate (14) of an integrally formed structure is provided at the bottom end of the clamping rod (15), and a first spring (13) is sleeved on the outside.

7. The multimodal chemical experiment teaching device based on microfluidic chip according to claim 1, characterized in that: The clamping rod (15) drives the limiting plate (14) to move via the first spring (13), thereby achieving rapid locking and unlocking between the rotating plate (9) and the mode changing plate (822).

8. The multimodal chemical experiment teaching device based on microfluidic chip according to claim 1, characterized in that: The detection unit (83) is equipped with a sensor (85) for collecting detection results.

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