Container convenient for quality inspection and storage of eye library cornea graft

Abstract

The utility model describes a container convenient for quality inspection and storage of eye reservoir corneal graft, which comprises a container body and a container cover, the bottom of the container body is provided with a plurality of prisms for supporting corneal sclera disc, and the end faces of the plurality of prisms form a supporting surface matched with the natural curvature of the corneal sclera disc. The plurality of prisms are arranged along the bottom of the container body, the distance between at least one pair of adjacent prisms is suitable for placing a storage device for storing an endothelial graft of a cornea, a boss is formed at the top of the container cover, and when the container cover is connected with the container body, the container cover and the container body form a sealed space; the top face of the boss and the supporting surface form a limiting space used for storing the eye library cornea graft, and the sealed space is communicated with the limiting space and the storage device. Therefore, the stability and the safety of storing the corneal graft of the eye library can be improved, and the corneal graft storage device can be used in cooperation with a storage device to store the endothelial graft of the cornea.

Description

Technical Field

[0001] The utility model relates to the field of medical devices, and particularly relates to a container which is convenient for quality inspection and preservation of corneal grafts in an eye bank. Background Art

[0002] A corneal graft refers to the excised ocular corneal tissue donated after the death of a corneal donor (i.e., the donor). The corneal graft is mainly used in corneal transplantation surgeries to treat various corneal diseases such as keratoconus, corneal ulcer, and corneal perforation. Generally, the corneal graft is not immediately applied clinically after being removed from the donor. Therefore, special preservation treatment is required for the corneal graft to extend its service life. To maintain the activity of corneal cells and the structural integrity of the corneal graft, the corneal graft is usually placed in a preservation solution and stored, transported, and detected under a low-temperature environment.

[0003] In the prior art, a corneal preservation bottle is usually used to preserve the corneal graft. The corneal preservation bottle generally forms a relatively independent accommodation space for storing the corneal graft inside the bottle body by the combination of the bottle cap and the bottle body. This accommodation space can limit the movement of the corneal graft to a certain extent, thereby reducing the risks such as slipping or rolling of the corneal graft during preservation or transportation. In addition, the accommodation space can communicate with the inside of the bottle body. When the preservation solution is filled inside the bottle body, the preservation solution can fill the accommodation space so that the corneal graft is immersed in the preservation solution.

[0004] However, the above-mentioned accommodation space is usually formed by a plurality of prisms for supporting the corneal graft in cooperation with the bottle cap. These prisms are often arranged at intervals around the central axis of the bottle body. The end face (i.e., the supporting end face) of the prism in contact with the corneal graft does not fully consider the natural curvature of the corneal graft, so that the supporting end face does not fit well with the corneal graft, making it difficult for the accommodation space to fix the corneal graft well. When detecting the corneal graft in the preservation bottle, it may be difficult to obtain a clear external image of the corneal graft due to the shaking or jitter of the corneal graft. In addition, since the endothelium of the cornea (i.e., the endothelial graft) is curly and difficult to be supported by a plurality of prisms, the endothelial graft is not suitable for being preserved in the above-mentioned accommodation space. In other words, the corneal preservation bottle in the prior art is not suitable for preserving the endothelial graft. Summary of the Invention

[0005] The present utility model is proposed in view of the above situation, and aims to provide a container which is convenient for quality inspection and preservation of corneal grafts in an eye bank. The container can improve the stability and safety of preserving corneal grafts in the eye bank, and can be used in cooperation with a preservation device for preserving the endothelial graft of the cornea to preserve the endothelial graft of the cornea. The container can improve the stability and safety of preserving corneal grafts in the eye bank and can facilitate the observation or inspection of the preserved corneal grafts in the eye bank.

[0006] To this end, the present utility model provides a container facilitating the quality inspection and preservation of corneal grafts in an eye bank. The corneal graft in the eye bank includes a cornea and a corneoscleral disc. The container includes a container body and a container lid detachably connected to the container body. A plurality of prisms for supporting the corneoscleral disc are provided at the bottom of the container body, and end faces of the plurality of prisms form a supporting surface adapted to the natural curvature of the corneoscleral disc. The plurality of prisms are spaced apart along the periphery of the bottom of the container body, and the distance between at least a pair of adjacent prisms is adapted to insert a preservation device for preserving the endothelial graft of the cornea. A boss is formed at the top of the container lid, and the boss has a top surface opposite to the bottom of the container body. When the container lid is connected to the container body, the container lid and the container body form a sealed space. The top surface of the boss and the supporting surface form a restrictive space for storing the corneal graft in the eye bank and restricting the displacement of the corneal graft in the eye bank. The sealed space communicates with the restrictive space and the preservation device respectively.

[0007] In the present utility model, since the supporting surface supports the entire corneal graft by supporting the corneoscleral disc, the supporting surface does not directly contact the cornea, thereby effectively reducing the risk of damage to the epithelial cells of the cornea caused by physical friction. In addition, since the supporting surface is adapted to the natural curvature of the corneoscleral disc, the fitting degree of the supporting surface and the corneoscleral disc can be improved, thereby improving the stability of the supporting surface in supporting the corneoscleral disc and being beneficial to improving the stability of storing the corneal graft. In addition, the stability of the corneal graft stored in the container can be improved through the restrictive space, so that the corneal graft is stored in the container in a stable posture. When the container is placed in different postures to inspect the corneal graft in the container, the corneal graft can still maintain a stable posture, thereby facilitating accurate and comprehensive observation or inspection of the corneal graft. In addition, since the distance between at least a pair of adjacent prisms is adapted to insert the preservation device, the container can facilitate the fixation of the preservation device, so that the container and the preservation device can be used in cooperation to preserve the endothelial graft of the cornea.

[0008] In addition, in the container for facilitating the quality inspection and preservation of corneal grafts in an eye bank according to the present utility model, optionally, the bottom of the container body has a first observation window, and a plurality of the prisms are arranged at intervals along the periphery of the first observation window. The top of the container lid has a second observation window and the second observation window is located on the top surface of the boss. In this case, by providing the first observation window at the bottom of the container body and arranging a plurality of prisms on the first observation window, the supporting surface is directly opposite to the first observation window. When the supporting surface supports the corneoscleral disc, it is convenient to observe or inspect the epithelial surface of the corneal graft through the first observation window. In addition, by providing the second observation window on the top surface of the boss, it is convenient to observe or inspect the endothelial surface of the corneal graft stored in the container through the second observation window. And since the first observation window and the second observation window are oppositely arranged at both ends of the container, it is convenient to comprehensively observe or inspect both sides of the corneal graft in the container from both ends of the container.

[0009] In addition, in the container for facilitating the quality inspection and preservation of corneal grafts in an eye bank according to the present utility model, optionally, the supporting surface includes a first arc surface and at least one second arc surface, the second arc surface is lower than the first arc surface and the area of the second arc surface is smaller than the area of the first arc surface. Wherein, the second arc surface is formed by steps generated by the end faces of a plurality of the prisms in the direction towards the central axis of the first observation window. In this case, since the diameter of the corneal graft falling on the second arc surface is usually small, when a surgeon takes the corneal graft located on the second arc surface clinically, it is convenient to prompt the surgeon that the corneal graft cannot be fixed in an artificial anterior chamber for further graft processing and other corneal grafts need to be selected.

[0010] In addition, in the container for facilitating the quality inspection and preservation of corneal grafts in an eye bank according to the present utility model, optionally, the end face of the prism includes a top surface and an inclined surface that is higher on the outside and lower on the inside, and the supporting surface is formed by the inclined surfaces of a plurality of the prisms. The top surface of the prism has a preset distance from the second observation window when the container lid and the container body are hermetically connected. In this case, due to the existence of the preset distance, the damage to the container itself caused by extrusion due to hard contact between the prism and the second observation window can be reduced. In addition, when the size of the corneoscleral disc is larger than the supporting surface, the preset distance can provide an extended space for the corneoscleral disc, so that the container is suitable for storing corneal grafts with a relatively large corneoscleral disc.

[0011] In addition, in the container for facilitating the quality inspection and preservation of corneal grafts in an eye bank according to the present utility model, optionally, the bottom of the container body includes a bottom plate and a recess formed in the bottom plate. The recess has a bottom surface opposite to the top surface of the boss, and the first observation window is located on the bottom surface of the recess. Thus, the risk of the first observation window being scratched (or abraded) can be reduced.

[0012] In addition, in the container for facilitating the quality inspection and preservation of corneal grafts in an eye bank according to the present utility model, optionally, the top of the container lid includes a top plate, and the boss is formed on the top plate. Thus, when the second observation window is disposed on the top surface of the boss, the risk of the second observation window being scratched (or abraded) can be reduced.

[0013] In addition, in the container for facilitating the quality inspection and preservation of corneal grafts in an eye bank according to the present utility model, optionally, the container lid and the container body establish a sealed connection by one of magnetic attraction, engagement, snap fit, or screwing. Thus, the flexibility of establishing a sealed connection between the container lid and the container body can be improved.

[0014] In addition, in the container for facilitating the quality inspection and preservation of corneal grafts in an eye bank according to the present utility model, optionally, the outer surface of the first side wall of the container body has a plurality of first inclined stripes, and the outer surface of the second side wall of the container lid has a plurality of second inclined stripes. When the container lid and the container body are sealed and connected by screwing, the plurality of first inclined stripes and the plurality of second inclined stripes form an indication mark to indicate the rotation direction of opening the container lid. In this case, the rotation direction of opening the container lid can be intuitively and conveniently indicated to the user (such as a doctor) through the indication mark. In addition, the plurality of first inclined stripes and the plurality of second inclined stripes can increase the contact friction force, enabling the user to conveniently open the container lid.

[0015] In addition, in the container for facilitating the quality inspection and preservation of corneal grafts in an eye bank according to the present utility model, optionally, an O-ring seal is included. The container lid has a groove for placing the O-ring seal, and the O-ring seal is compressed when the container lid and the container body are sealed and connected. Thus, the liquid-tight sealing performance between the container lid and the container body can be improved through the O-ring seal.

[0016] In addition, in the container for facilitating the quality inspection and preservation of corneal grafts in an eye bank according to the present utility model, optionally, the preservation device is first placed into the fixing device and then placed into the spacing between adjacent prisms. The preservation device includes a glass tube for storing the endothelial graft of the cornea and a rubber stopper detachably connected to the glass tube and having a plurality of through holes. In this case, it is convenient to take out the preservation device from the container through the fixing device. In addition, when the rubber stopper plugs the opening of the glass tube, the inside of the glass tube can communicate with the outside through the plurality of through holes, facilitating the preservation liquid to enter the inside of the glass tube.

[0017] According to the present utility model, it is possible to provide a container that facilitates the quality inspection and preservation of corneal grafts in an eye bank. This container can improve the stability and safety of preserving corneal grafts in the eye bank and can be used in conjunction with a preservation device for preserving the endothelial grafts of the cornea to preserve the endothelial grafts of the cornea. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The present utility model will now be further explained in detail only by way of examples with reference to the accompanying drawings.

[0019] Figure 1 FIG. is a schematic diagram showing the application scenario of the container involved in the example of the present utility model.

[0020] Figure 2 FIG. is a schematic diagram showing the container body involved in the example of the present utility model.

[0021] Figure 3 FIG. is a schematic diagram showing the arrangement of multiple prisms spaced apart from each other involved in the example of the present utility model.

[0022] Figure 4A FIG. is a schematic diagram showing the first embodiment of the spacing between adjacent prisms where the preservation device is inserted involved in the example of the present utility model.

[0023] Figure 4B FIG. is a schematic diagram showing the second embodiment of the spacing between adjacent prisms where the preservation device is inserted involved in the example of the present utility model.

[0024] Figure 4C FIG. is a schematic diagram showing the third embodiment of the spacing between adjacent prisms where the preservation device is inserted involved in the example of the present utility model.

[0025] Figure 5 FIG. is a schematic diagram showing the preservation device and the fixing device involved in the example of the present utility model.

[0026] Figure 6 FIG. is a cross-sectional view of the container involved in the example of the present utility model.

[0027] Figure 7 FIG. is a schematic cross-sectional view of the prism involved in the example of the present utility model.

[0028] Figure 8 FIG. is a cross-sectional view of the container body involved in the example of the present utility model.

[0029] Figure 9 FIG. is a cross-sectional view of the container lid involved in the example of the present utility model.

[0030] Figure 10 FIG. is a side view of the container involved in the example of the present utility model.

[0031] Figure 11 It is a schematic diagram showing the positional relationship between the container lid and the O-ring seal involved in the example of the present utility model.

[0032] Figure 12 It is a bottom view of the container body involved in the example of the present utility model.

[0033] Description of reference numerals:

[0034] 1... Container, 10... Container body, 11... Prism, 110... Step, 112... Top surface of the prism, 114... Inclined surface, 12... First observation window, 13... Bottom, 14... Bottom plate, 16... Recess, 160... Bottom surface, 17... First oblique stripe, 15... First side wall, 152... Inner side wall, 154... Outer side wall, 156... Connecting column, 20... Container lid, 21... Top, 22... Second observation window, 23... Boss, 230... Top surface of the boss, 232... Side surface of the boss, 24... Top plate, 25... Second side wall, 26... Fourth plane, 27... Second oblique stripe, S... Support surface, S1... First arc surface, S2... Second arc surface, A... Sealing space, B... Restricted space, M... Indication mark, L... Central axis, d... Spacing, D... Rotation direction, 3... Corneal graft, 30... Cornea, 32... Corneoscleral disc, 4... Preservation device, 40... Glass tube, 402... Opening, 41... Rubber stopper, 42... Through hole, 5... O-ring seal, 6... Fixing device, 60... First hole, 62... Second hole, 64... Third hole. Detailed implementation manners

[0035] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all of the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present utility model.

[0036] It should be noted that the terms "first", "second", "third", "fourth", etc. in the description, claims and above-mentioned drawings of the present utility model are used to distinguish different objects, rather than to describe a specific order. In addition, the terms "comprising" and "having" and any variations thereof are intended to cover non-exclusive inclusion. For example, a process, method, system, product or device comprising a series of steps or units is not limited to the listed steps or units, but optionally further includes steps or units not listed, or optionally further includes other steps or units inherent to these processes, methods, products or devices. In the following description, the same reference numerals are given to the same components, and repeated descriptions are omitted. Additionally, the drawings are only schematic diagrams, and the proportional sizes between components or the shapes of components, etc. may be different from the actual ones.

[0037] The container for facilitating the quality inspection and preservation of corneal grafts in an eye bank according to the present utility model can be used to preserve corneal grafts in an eye bank and can improve the stability and safety of preserving corneal grafts in an eye bank. In addition, due to the good stability of corneal grafts in an eye bank during the preservation process, it is convenient to accurately and comprehensively observe or inspect the corneal grafts in the container. Additionally, the container can also be used in conjunction with a preservation device for preserving the endothelial grafts of the cornea to preserve the endothelial grafts of the cornea (also referred to as endothelial grafts).

[0038] The container for facilitating the quality inspection and preservation of corneal grafts in an eye bank according to the present utility model can be simply referred to as a container, and sometimes can also be called a preservation container, preservation bottle, etc.

[0039] Hereinafter, the container related to the present utility model will be described with reference to the drawings.

[0040] Figure 1 FIG. is a schematic diagram of the application scenario of the container 1 related to the example of the present utility model.

[0041] In some examples, in the field of corneal transplantation, an eye bank can refer to an institution that specifically preserves and manages corneal grafts 3 used for corneal transplantation. In some examples, corneal grafts in an eye bank can refer to corneal grafts 3 preserved in an eye bank. For the convenience of description, hereinafter, the corneal grafts in an eye bank will be simply referred to as corneal grafts 3.

[0042] In some examples, referring to Figure 1 , the corneal graft 3 can include a cornea 30 and a corneoscleral disc 32. Among them, the corneoscleral disc 32 can refer to the scleral tissue surrounding the periphery of the cornea 30. In some examples, the corneal graft 3 is generally disc-shaped, and the disc-shaped corneal graft 3 can correspond to the natural curvature of the eyeball.

[0043] In some examples, referring to Figure 1, the container 1 involved in the present utility model may include a container body 10 and a container lid 20. The container body 10 can be used to accommodate the corneal graft 3 and the corneal preservation solution (hereinafter simply referred to as the preservation solution).

[0044] In some examples, the container lid 20 can be detachably connected to the container body 10. In some examples, the detachable connection between the container lid 20 and the container body 10 can mean that the container lid 20 and the container body 10 can form a firm connection, and they can be conveniently detached without using tools or performing complex operations. Further, the detachable connection method can also allow the container lid 20 and the container body 10 to be connected and detached multiple times.

[0045] In some examples, when the container lid 20 is connected to the container body 10, the container lid 20 can seal the container body 10.

[0046] Figure 2 is a schematic structural view of the container body 10 involved in the examples of the present utility model. Figure 3 is a schematic view showing the arrangement of multiple prisms at intervals involved in the examples of the present utility model.

[0047] In some examples, referring to Figure 2 , multiple prisms 11 can be provided at the bottom 13 of the container body 10, and the multiple prisms 11 can be used to support the corneoscleral disc 32.

[0048] In some examples, referring to Figure 2 , the end faces of the multiple prisms 11 can form a support surface S, and the support surface S can be adapted to the natural curvature of the corneoscleral disc 32. In this case, since the support surface S is adapted to the natural curvature of the corneoscleral disc 32, the fitting degree between the support surface S and the corneoscleral disc 32 can be improved, thereby improving the stability of the support surface S in supporting the corneoscleral disc 32, which is beneficial to improving the storage stability of the corneal graft 3.

[0049] In some examples, the support surface S can be adapted to the natural curvature of the corneoscleral disc 32 can mean that the curvature of the support surface S is the same as or close to the natural curvature of the corneoscleral disc 32. Additionally, the natural curvature of the corneoscleral disc 32 can refer to the curved shape of the cornea 30 and its surrounding scleral region, and the natural curvature of the corneoscleral disc 32 can characterize the degree of curvature of the cornea 30 and its surrounding scleral region.

[0050] In some examples, the support surface S can support the corneal graft 3 by supporting the corneoscleral disc 32. In this case, since the support surface S supports the entire corneal graft 3 by supporting the corneoscleral disc 32, the support surface S does not directly contact the cornea 30, thereby effectively reducing the risk of damage to the epithelial cells of the cornea 30 caused by physical friction.

[0051] In some examples, the corneal graft 3 can be placed on the support surface S with the epithelial surface of the cornea 30 facing downwards. In other words, for the corneal graft 3 placed on the support surface S, the epithelial surface of the cornea 3 can face the bottom 13 of the container body 10. In this case, the corneal graft 3 can be placed on the support surface S in a natural posture, which is beneficial to improving the stability of the support surface S in supporting the corneal graft 3.

[0052] Figure 4A It is a schematic diagram showing the 1st embodiment of the distance between the preservation devices placed in adjacent prisms related to the examples of the present utility model.

[0053] In some examples, referring to Figure 2 , a plurality of prisms 11 can be arranged at intervals along the periphery of the bottom 13 of the container body 10. That is, a plurality of prisms 11 can be arranged at intervals around the central axis L of the container body 10 on the bottom 13 of the container body 11 (refer to Figure 3 ). Thus, the balance of the plurality of prisms 11 in supporting the corneoscleral disc 32 can be improved.

[0054] In some examples, referring to Figure 3 , the distance d between at least a pair of adjacent prisms 11 can be adapted to insert the preservation device 4, and the preservation device 4 can be used to preserve the endothelial graft.

[0055] In some examples, referring to Figure 4A , the distance d between at least a pair of adjacent prisms 11 can be adapted to insert the preservation device 4 to fix the preservation device 4 to the container body 10. In this case, it is convenient for the container 1 to fix the preservation device 4, so that the container 1 and the preservation device 4 can be used in cooperation to preserve the endothelial graft. For example, in the example shown in Figure 3 , the distance d between the prism 11a and the prism 11b and the distance d between the prism 11c and the prism 11d can be adapted to insert the preservation device 4 to fix the preservation device 4 to the container 1.

[0056] In some examples, referring to Figure 3 , in the direction close to the central axis L of the container body 10, the distance d between adjacent prisms 11 can gradually decrease. The distance d between adjacent prisms 11 being adapted to insert the preservation device 4 can mean that the minimum distance d between adjacent prisms 11 is adapted to insert the preservation device. In some examples, the distance d between adjacent prisms 11 can also refer to the minimum distance between a pair of adjacent prisms 11.

[0057] In some examples, the preservation device 4 can be a syringe (such as a glass syringe for corneal endothelial grafts), and the corneal graft 3 can be pre-loaded in the syringe after the processing of the endothelial graft is completed in the eye bank. That is, the syringe can be used to pre-load the endothelial graft.

[0058] In the present utility model, by using the distance d between at least a pair of adjacent prisms 11, the storage device 4 storing the endothelial graft is fixed to the container 1, enabling the container 1 and the storage device 4 to be used in cooperation to store the endothelial graft in the container 1, thereby avoiding the risk of contamination of the endothelial graft caused by multiple transfers of containers (or instruments).

[0059] In some examples, preferably, referring to Figure 3 , among the multiple prisms 11, the distances d between two pairs of adjacent prisms 11 may be suitable for inserting the storage device 4. And the two pairs of adjacent prisms 11 may be symmetric about the central axis L of the container body 10. In this case, the distances d between the two pairs of adjacent prisms 11 can be on a straight line. When the storage device 4 is inserted into the distance d, the two ends of the storage device 4 can be fixed, thereby improving the stability of fixing the storage device 4.

[0060] Figure 4B FIG. is a schematic diagram of the second embodiment showing the storage device 4 according to the example of the present utility model inserted into the distance d between the adjacent prisms 11. Figure 4C FIG. is a schematic diagram of the third embodiment showing the storage device 4 according to the example of the present utility model inserted into the distance d between the adjacent prisms 11. Figure 5 FIG. is a schematic diagram showing the storage device 4 and the fixing device 6 according to the example of the present utility model.

[0061] In some examples, referring to Figure 4B , the storage device 4 can also be first inserted into the fixing device 6 and then into the distance d between the adjacent prisms 11. That is, the storage device 4 can be first assembled to the fixing device 6 and then the storage device 4 can be stored in the container 1. In this case, it is convenient to take out the storage device 4 from the container 1 through the fixing device 6.

[0062] In some examples, the fixing device 6 can cooperate with medical devices such as tweezers or clips to take out the storage device 4 from the container 1. In some examples, referring to Figure 4B , the fixing device 6 can include a first hole 60 and a second hole 62, and the first hole 60 and the second hole 62 can be oppositely arranged. Medical devices such as tweezers or clips can be inserted into the first hole 60 and the second hole 62 to clamp the fixing device 6 and take out the fixing device 6 from the container 1.

[0063] In some examples, referring to Figure 5 , the fixing device 6 can include a third hole 64. The storage device 4 can be assembled to the fixing device 6 in a manner of being inserted into the third hole 64.

[0064] In some examples, after the storage device 4 is assembled to the fixing device 6 and inserted into the distance d between the adjacent prisms 11, it may not contact the prism 11. For example, referring to Figure 4C, one end of the storage device 4 can have a gap with the prism 11 after being placed in the spacing d between adjacent prisms 11. Thus, damage to the prism 11 or the storage device 4 caused by extrusion due to hard contact between the prism 11 and the storage device 4 can be reduced.

[0065] In some examples, referring to Figure 5 , the storage device 4 can include a glass tube 40 and a rubber stopper 41. The rubber stopper 41 can be detachably connected to the glass tube 40.

[0066] In some examples, the glass tube 40 can be used to store the endothelial graft of the cornea 30, and the rubber stopper 41 can be used to block the glass tube 40. Specifically, the glass tube 40 can have an opening 402, and the endothelial graft can be loaded into the glass tube 40 through the opening 402. The rubber stopper 30 can be detachably connected to the glass tube 40 in a manner of blocking the opening 402 of the glass tube 40.

[0067] In some examples, the rubber stopper 41 can have a plurality of through holes 42. When the rubber stopper 41 blocks the opening 402 of the glass tube 40, the inside of the glass tube 40 can communicate with the outside through the plurality of through holes 42, so as to facilitate the preservation liquid to enter the inside of the glass tube 40.

[0068] Figure 6 is a cross-sectional view showing the container 1 involved in the example of the present invention.

[0069] As described above, the container 1 can include a container lid 20 detachably connected to the container body 10. In some examples, referring to Figure 6 , a boss 23 can be formed on the top 21 of the container lid 20, and the boss 23 can have a top surface 230 opposite to the bottom 13 of the container body 10. In some examples, the top surface 230 of the boss 23 can cooperate with the support surface S to form a space for storing the corneal graft 3.

[0070] In some examples, referring to Figure 6 , when the container lid 20 is connected to the container body 10, the container lid 20 and the container body 10 can form a sealed space A, and the top surface 230 of the boss 23 and the support surface S can form a restricted space B. In some examples, the sealed space A can be used to load the preservation liquid, and the restricted space B can be used to store the corneal graft 3.

[0071] In some examples, the restrictive space B can restrict the displacement (or movement) pair of the corneal graft 3 stored in the restrictive space B. In this case, the stability of the corneal graft 3 stored in the container 1 can be improved through the restrictive space B, so that the corneal graft 3 is stored in the container 1 in a stable posture. When the container 1 is placed in different postures to inspect the corneal graft 3 in the container 1, the corneal graft 3 can still maintain a stable posture, thereby facilitating accurate and comprehensive observation or inspection of the corneal graft 3.

[0072] It should be noted that in the present utility model, the restrictive space B restricting the displacement of the corneal graft 3 does not mean that the corneal graft 3 cannot move at all in the restrictive space B, but means that the corneal graft 3 stored in the restrictive space B can only move within a limited range, and the posture of the corneal graft 3 can be basically maintained stable. And because the corneal graft 3 is immersed in the preservation liquid, the corneal graft 3 will not be damaged due to collision (or friction) during the movement within the limited range.

[0073] In some examples, referring to Figure 6 , when the corneal graft 3 is stored in the restrictive space B, the top surface 230 of the boss 23 can be spaced from the cornea 30. In this case, while ensuring good stability of the corneal graft 3, the risk of damage to the endothelial cells and / or epithelial cells of the cornea 30 caused by physical friction can be further reduced, thereby improving the safety of storing the corneal graft 3.

[0074] In some examples, the restrictive space B can be a relatively independent accommodation space within the sealed space A. In some examples, the sealed space A and the restrictive space B can communicate with each other (for example, the restrictive space B can communicate with the sealed space A through the intervals between multiple prisms 11). In this case, when the container body 10 is loaded with the preservation liquid, the preservation liquid can be made to fill the restrictive space B so that the corneal graft 3 is immersed in the preservation liquid.

[0075] In some examples, the storage device 4 can be a relatively independent storage space within the sealed space A. In some examples, the sealed space A and the storage device 4 can communicate with each other. For example, in Figure 5 the example shown, the rubber stopper 41 of the storage device 4 can be provided with a plurality of through holes 42 ( Figure 5 schematically marking one of the through holes 42), and the glass tube 40 can communicate with the sealed space A through the plurality of through holes 42 (for example, fluid communication). In this case, when the container body 10 is loaded with the preservation liquid, the preservation liquid can be made to enter and fill the inside of the storage device 4 so that the endothelial graft is immersed in the preservation liquid.

[0076] In some examples, referring to Figure 6, the bottom 13 of the container body 10 may have a first observation window 12. In some examples, the first observation window 12 can be used to observe the interior of the container 1 from the bottom of the container body 10. Thus, it is possible to facilitate observing or inspecting the endothelial surface of the corneal graft 3 stored in the container 1 through the first observation window 12.

[0077] In some examples, referring to Figure 6 , the first observation window 12 may be provided with a plurality of prisms 11 ( Figure 6 schematically identifying two of the prisms 11), and the plurality of prisms 11 may be spaced along the periphery of the first observation window 12. That is, the plurality of prisms 11 may be spaced around the central axis L of the first observation window 12 at the periphery of the first observation window 12. In this case, it is possible to improve the balance of the plurality of prisms 11 supporting the corneoscleral disc 32, and since there are intervals between the plurality of prisms 11, it is possible to make the restricted space B and the sealed space A communicate with each other. In addition, by providing the first observation window 12 at the bottom 13 of the container body 10 and the plurality of prisms 11 being provided on the first observation window 12, the support surface S is directly opposite to the first observation window 12. When the support surface S supports the corneoscleral disc 32, it is possible to conveniently observe or inspect the epithelial surface of the corneal graft 3 through the first observation window 12.

[0078] In some examples, the central axis L of the first observation window 12 may refer to the central axis L of the container body 10. Additionally, in some examples, the plurality of prisms 11 may also be evenly arranged around the periphery of the first observation window 12.

[0079] In some examples, referring to Figure 6 , the top 21 of the container lid 20 may have a second observation window 22. In some examples, the second observation window 22 can be used to observe the interior of the container 1 from the top 21 of the container lid 20. Thus, it is possible to facilitate observing or inspecting the corneal graft 3 stored in the container 1 through the second observation window 22.

[0080] In some examples, referring to Figure 6 , the second observation window 22 may be located on the top surface 230 of the boss 23. Thus, by providing the second observation window 22 on the top surface 230 of the boss 23, it is possible to conveniently observe or inspect the corneal graft 3 stored in the container 1 through the second observation window 22.

[0081] In some examples, referring to Figure 6, the second observation window 22 can be arranged opposite to the first observation window 12. Specifically, since the top surface 230 of the boss 23 faces the bottom 13 of the container body 10, when the second observation window 22 is provided on the top surface 230 of the boss 23 and the first observation window 12 is provided on the bottom 13 of the container body 10, the second observation window 22 can be arranged opposite to the first observation window 12. In this case, since the first observation window 12 and the second observation window 22 are arranged opposite to each other at both ends of the container 1, it is convenient to comprehensively observe or inspect both sides of the corneal graft 3 in the container 1 from both ends of the container 1.

[0082] In some examples, observing or inspecting the corneal graft 3 may refer to performing slit lamp microscopy, corneal endothelial cell detection, or anterior segment OCT examination on the corneal graft 3 to obtain the physiological state of the corneal graft 3. In some examples, observing or inspecting the corneal graft 3 may also mean performing a quality inspection on the corneal graft 3.

[0083] In some examples, since the support surface S faces the first observation window 12 and the first observation window 12 faces the second observation window 22, the restricted space B can also be used to observe or inspect the pair of corneal grafts 3 stored in the restricted space B. In some examples, the restricted space B can also be referred to as a corneal graft observation room or a corneal graft inspection room.

[0084] In some examples, the first observation window 12 and the second observation window 22 can be inspection windows formed of transparent glass.

[0085] Figure 7 is a schematic cross-sectional view of the prism 11 involved in the example of the present invention.

[0086] In some examples, the support surface S formed by a plurality of prisms 11 may include a first arc surface S1 and at least one second arc surface S2 ( Figure 3 schematically shows a first arc surface S1 and a second arc surface S2), wherein the second arc surface S2 can be lower than the first arc surface S1 and the area of the second arc surface S2 can be smaller than the area of the first arc surface S1 (see Figure 3 ).

[0087] In some examples, the first arc surface S1 can be used to support the corneal graft 3 with a larger diameter. In addition, the second arc surface S2 can be used to support the corneal graft 3 with a smaller diameter. In this case, since the diameter of the corneal graft 3 falling on the second arc surface S2 is usually smaller, when the surgeon takes the corneal graft 3 located on the second arc surface S2 clinically, it is convenient to prompt the surgeon that the corneal graft 3 cannot be fixed in the artificial anterior chamber for further graft processing and other corneal grafts need to be selected.

[0088] In some examples, the number of the second arcuate surfaces S2 can be multiple, and the multiple second arcuate surfaces S2 can be used to support corneal implants 3 with different diameters.

[0089] In some examples, the second arcuate surface S2 can be formed by end faces of multiple prisms 11. Specifically, the second arcuate surface S2 can be formed by steps 110 generated by end faces of multiple prisms 11 in a direction towards the central axis L of the container body 10 ( Figure 3 schematically identifying the step 110 of one of the prisms 11). Thus, the second arcuate surface S2 formed by multiple steps 110 can improve the stability of the second arcuate surface S2 in supporting the corneal implant 3.

[0090] In some examples, referring to Figure 7 , the end face of the prism 11 can include a top face 112 and an inclined face 114 with a higher outer part and a lower inner part. Among them, the above-mentioned supporting surface S can be formed by inclined faces 114 of multiple prisms 11.

[0091] In some examples, referring to Figure 6 , the top face 112 of the prism 11 can have a preset spacing from the second observation window 22 when the container lid 20 is sealingly connected to the container body 10. In this case, due to the existence of the preset spacing, the damage to the container 1 itself caused by extrusion due to hard contact between the prism 11 and the second observation window 22 can be reduced. In addition, when the size of the corneoscleral disc 32 is larger than the supporting surface S, the preset spacing can provide an extended space for the corneoscleral disc 32, so that the container 1 is suitable for storing corneal implants 3 with a relatively large corneoscleral disc 32.

[0092] However, the present utility model is not limited thereto. In other examples, the top face 112 of the prism 11 can abut against the second observation window 22 to form a restricted space B when the container lid 20 is sealingly connected to the container body 10. Thus, the situation where the corneal implant 3 slides out of the restricted space B can be inhibited.

[0093] Figure 8 is a cross-sectional view showing the container body 10 involved in the example of the present utility model. Figure 9 is a cross-sectional view showing the container lid 20 involved in the example of the present utility model.

[0094] In some examples, referring to Figure 8 , the bottom 13 of the container body 10 can include a bottom plate 14 and a recess 16, and the recess 16 can be formed on the bottom plate 14. In some examples, the recess 16 can be recessed towards the inside of the container body 10. In some examples, the recess 16 can have a bottom face 160, the bottom face 160 can be opposite to the top face 230 of the boss 23, and in addition, the first observation window 12 can be located on the bottom face 160 of the recess 16. Thus, the risk of the first observation window 12 being scratched (or abraded) can be reduced.

[0095] In some examples, referring to Figure 9 , the top 21 of the container lid 20 may include a top plate 24, and a boss 23 may be formed on the top plate 24. In some examples, the boss 23 may be recessed toward the inside of the container lid 20. That is, the boss 23 may be formed by the top plate 24 being recessed toward the inside of the container lid 20. Thus, when the second observation window 22 is disposed on the top surface 230 of the boss 23, the risk of the second observation window 22 being scratched (or scuffed) can be reduced. In some examples, the boss 23 may be cylindrical.

[0096] In some examples, the container lid 20 and the container body 10 may establish a sealed connection by one of magnetic attraction, engagement, snap fit, or screwing. Thus, the flexibility of establishing a sealed connection between the container lid 20 and the container body 10 can be improved.

[0097] In some examples, preferably, the container lid 20 and the container body 10 may establish a sealed connection by screwing. For example, an internal thread may be provided on the inner wall of the container lid 20, and an external thread may be provided on the outer wall of the container body 10. By the cooperation of the internal thread and the external thread, a detachable sealed connection can be established between the container lid 20 and the container body 10.

[0098] Figure 10 is a side view showing the container 1 involved in the example of the present utility model.

[0099] In some examples, referring to Figure 10 , the outer surface of the first side wall 15 of the container body 10 may have a plurality of first inclined stripes 17. The plurality of first inclined stripes 17 may be used for anti-slip. In some examples, the outer surface of the second side wall 25 of the container lid 20 may have a plurality of second inclined stripes 27. The plurality of second inclined stripes 27 may be used for anti-slip.

[0100] In some examples, referring to Figure 10 , the plurality of first inclined stripes 17 may be combined with the plurality of second inclined stripes 27 to form an indication mark M. In some examples, when the container lid 20 and the container body 10 are sealed and connected by screwing, the plurality of first inclined stripes 17 and the plurality of second inclined stripes 27 may form an indication mark M, and the indication mark M may indicate the rotation direction D of opening the container lid 20 (refer to Figure 10 ). In this case, through the indication mark M, the rotation direction D of opening the container lid 20 can be intuitively and conveniently indicated to the user (such as a doctor). In addition, the plurality of first inclined stripes 17 and the plurality of second inclined stripes 27 can increase the contact friction force, enabling the user to conveniently open the container lid 20.

[0101] In some examples, the indicating mark M can also be used to indicate that the container lid 20 is rotated into place. Specifically, during the rotation of the container lid 20 relative to the container body 10, when the plurality of first inclined stripes 17 and the plurality of second inclined stripes 27 form the indicating mark M, it can be confirmed that the container lid 20 has been rotated into place and a sealed connection has been established between the container lid 20 and the container body 10.

[0102] Figure 11 is a schematic diagram showing the positional relationship between the container lid 20 and the O-ring seal 5 involved in the examples of the present utility model.

[0103] In some examples, referring to Figure 11 , the container 1 of the present utility model may further include an O-ring seal 5, and the O-ring seal 5 can be used to seal the connection between the container lid 20 and the container body 10.

[0104] In some examples, the container lid 20 may have a groove, and the groove can be used to place the O-ring seal 5. In some examples, the side surface 232 of the boss 23 may have a groove, and the groove may be an annular groove formed on the side surface 232 of the boss 23, so that the O-ring seal 5 can be disposed on the side surface 232 of the boss 23 (refer to Figure 11 ). In this case, after the container lid 20 is placed on the container body 10, even if the container lid 20 is not tightly connected to the container body 10, the O-ring seal 5 can still play a sealing role. Thus, the flexibility of the O-ring seal 5 to seal the connection between the container lid 20 and the container body 10 can be improved.

[0105] In some examples, when the O-ring seal 5 is placed in the groove 28, the O-ring seal 5 may partially protrude outside the groove 28. In some examples, the O-ring seal 5 may be compressed when the container lid 20 and the container body 10 are in a sealed connection. Thus, the liquid-tight sealing performance between the container lid 20 and the container body 10 can be improved through the O-ring seal 5.

[0106] Figure 12 is a bottom view showing the container body 10 involved in the examples of the present utility model.

[0107] In some examples, the first side wall 15 of the container body 10 may be a double-layer structure. In some examples, referring to Figure 8 or Figure 12, the first side wall 15 of the container body 10 may include an inner side wall 152 and an outer side wall 154 from the inside outwards, and there may be a gap between the inner side wall 152 and the outer side wall 154. In this case, by designing the first side wall 15 of the container body 10 as a double-layer structure, the strength of the first side wall 15 can be enhanced, and the risk of damage (such as rupture) to the first side wall 15 can be reduced. In addition, since the first side wall 15 is a double-layer structure, it is convenient to fix the container 1 to the detection instrument by using the gap between the double-layer structures, so that the container 1 and the detection instrument can be used in a matching manner, thereby facilitating the use of the detection instrument to observe or inspect the corneal graft 3 in the container 1.

[0108] In some examples, referring to Figure 12 , the inner side wall 152 may be connected to the outer side wall 154 through a plurality of connecting columns 156. Thereby, the stability of the overall structure of the container body 10 can be improved. In some examples, the connecting columns 156 may extend along the axial direction of the container body 10.

[0109] In some examples, referring to Figure 12 , the number of the connecting columns 156 may be two, and the two connecting columns 156 may be symmetrically distributed around the central axis L of the container body 10.

[0110] Although the present invention has been specifically described above in combination with the drawings and examples, it can be understood that the above description does not limit the present invention in any form. Those skilled in the art can make deformations and changes to the present invention according to needs without departing from the essence and scope of the present invention, and these deformations and changes all fall within the scope of the present invention.

Claims

1. A container for facilitating quality inspection and storage of corneal grafts in an eye bank, wherein the corneal grafts in the eye bank include a cornea and a corneoscleral disc, characterized in that: The container comprises a container body and a container cover detachably connected to the container body. The bottom of the container body is provided with a plurality of prisms for supporting the cornea-sclera disc, and the end faces of the plurality of prisms form a supporting surface adapted to the natural curvature of the cornea-sclera disc. The plurality of prisms are arranged at intervals along the periphery of the bottom of the container body, and the spacing between at least one pair of adjacent prisms is suitable for placing a storage device for storing corneal endothelial grafts. A boss is formed on the top of the container cover, and the boss has a top surface opposite to the bottom of the container body. When the container cover is connected to the container body, the container cover and the container body form a sealed space, the top surface of the boss and the supporting surface form a restrictive space for storing the eye bank corneal graft and limiting the displacement of the eye bank corneal graft, and the sealed space is respectively communicated with the restrictive space and the storage device.

2. The container for facilitating quality inspection and storage of corneal grafts in an eye bank according to claim 1, characterized in that: The bottom of the container body is provided with a first observation window, a plurality of the prisms are arranged at intervals along the periphery of the first observation window, the top of the container cover is provided with a second observation window and the second observation window is located on the top surface of the boss.

3. The container for facilitating quality inspection and storage of corneal grafts in an eye bank according to claim 2, characterized in that: The support surface includes a first arcuate surface and at least one second arcuate surface, wherein the second arcuate surface is lower than the first arcuate surface and the area of ​​the second arcuate surface is smaller than the area of ​​the first arcuate surface, The second arc-shaped surface is formed by steps generated by the end surfaces of a plurality of the prisms in a direction toward the central axis of the first observation window.

4. The container for facilitating quality inspection and storage of corneal grafts in an eye bank according to claim 2, characterized in that: The end surface of the prism includes a top surface and an inclined surface that is higher outside and lower inside. The supporting surface is formed by a plurality of inclined surfaces of the prism. The top surface of the prism has a preset distance from the second observation window when the container cover is sealed and connected to the container body.

5. The container for facilitating quality inspection and storage of corneal grafts in an eye bank according to claim 2, characterized in that: The bottom of the container body includes a bottom plate and a recessed portion formed on the bottom plate, the recessed portion has a bottom surface opposite to the top surface of the boss, and the first observation window is located on the bottom surface of the recessed portion.

6. The container for facilitating quality inspection and storage of corneal grafts in an eye bank according to claim 2, characterized in that: The top of the container cover comprises a top plate, and the boss is formed on the top plate.

7. The container for facilitating quality inspection and storage of corneal grafts in an eye bank according to claim 1, characterized in that: The container cover and the container body are sealed and connected by magnetic attraction, meshing, snap-fitting or screw connection.

8. The container for facilitating quality inspection and storage of corneal grafts in an eye bank according to claim 7, characterized in that: The outer surface of the first side wall of the container body has a plurality of first oblique stripes, and the outer surface of the second side wall of the container cover has a plurality of second oblique stripes. When the container cover is sealed and connected to the container body by screwing, the plurality of first oblique stripes and the plurality of second oblique stripes form an indicator mark to indicate the rotation direction for opening the container cover.

9. The container for facilitating quality inspection and storage of corneal grafts in an eye bank according to claim 1, characterized in that: An O-ring seal is included. The side surface of the boss has a groove for placing the O-ring seal. The O-ring seal is squeezed when the container cover is sealed and connected to the container body.

10. The container for facilitating quality inspection and storage of corneal grafts in an eye bank according to claim 1, characterized in that: The storage device is first placed in the fixing device and then placed in the spacing between adjacent prisms. The storage device includes a glass tube for storing corneal endothelial grafts and a rubber plug detachably connected to the glass tube and having a plurality of through holes.

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