Multilayer assembled stem cell culture plate

By using the combination of springs, sleeves, sleeve rods and through holes in the multi-layer assembled stem cell culture plate, the sliding speed of the connecting block is controlled, and combined with the design of fixed keys and pressing keys, the problem of operation is solved and the problem of inconvenient connection is achieved, and the effect of easy and efficient operation and extended service life is achieved.

CN222975197UActive Publication Date: 2025-06-13HENAN INTECEL BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202421830730.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-07-31
Publication Date
2025-06-13
Estimated Expiration
2034-07-31

AI Technical Summary

Technical Problem

The existing multi-layer assembled stem cell culture plates Due to the complexity of the multi-layer structure, operators need to exert greater force when separating or extracting the underlying culture plates, resulting in laborious operation, inefficient efficiency and may affect cell growth and development.

Method used

A multi-layer assembled stem cell culture plate is designed, which adopts the cooperation of springs, sleeves, sleeve rods and through holes. The elastic potential energy of the spring promotes the sliding of the connecting block, controls the sliding speed, reduces the force needs of the operator, and achieves convenient connection and separation through the cooperation of fixed keys and pressing keys.

Benefits of technology

It realizes the reduction of the force demand for operators when sliding manually, reduces the risk of damage to the culture plate due to excessive force or improper operation, extends the service life of the culture plate, and improves the convenience and accuracy of operation.

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Abstract

The utility model provides a multi-layer assembled stem cell culture plate and belongs to the technical field of culture plates. Comprising at least two culture plate bodies which are used for culturing stem cells; the number of the connecting blocks is at least four, the connecting blocks are detachably and stably connected with the culture plate body, and the connecting blocks are evenly distributed on the two sides of the culture plate body; the number of the side plates is two, the side plates are located on the two sides of the culture plate body, the side plates are connected with the culture plate body through connecting blocks, and the side plates are connected with the connecting blocks in a sliding mode. Through cooperation of the spring, the sleeve, the sleeve rod and the through hole, the effects of providing auxiliary power and controlling the sliding speed when the culture plate is operated are achieved, and meanwhile through cooperation of structures such as the fixing key and the pressing key, the effects of convenient and stable connection and rapid unlocking of the side plate and the connecting block are achieved.
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Description

Technical Field

[0001] The utility model relates to the technical field of culture plates, and particularly relates to a multi-layer assembled stem cell culture plate. Background Art

[0002] Stem cell research plays an extremely important role in the field of modern biomedicine; stem cells have the ability of self-renewal and differentiation into multiple cell types, bringing great hope for disease treatment, tissue repair and regenerative medicine; in the process of culturing stem cells, culture plates are indispensable tools; with the continuous in-depth research and expanding application scope of stem cells, the requirements for stem cell culture plates are also increasing day by day; traditional single-layer culture plates have limitations such as low space utilization rate and low culture efficiency when dealing with the culture needs of a large number of stem cells; in order to meet the needs of large-scale and efficient stem cell culture, multi-layer assembled stem cell culture plates have emerged.

[0003] However, in the actual application of existing multi-layer assembled stem cell culture plates, due to the complexity of the multi-layer structure, the friction between layers and the mutual extrusion effect, operators need to apply a large amount of force when separating or pulling out the lower culture plate; this laborious operation not only increases the work intensity and reduces the operation efficiency, but also easily causes the culture plate to be suddenly pulled out or stuck due to uneven force application, which has an adverse impact on the internal cell culture environment and may even affect the growth and development of cells; especially in the case of frequent operations or dealing with multiple culture plates, this problem is more prominent, seriously restricting the smooth progress of stem cell culture work. Content of the Utility Model

[0004] The technical problem to be solved by the utility model is to provide a multi-layer assembled stem cell culture plate to solve the technical problems of laborious manual operation; as well as the inconvenient connection and operation between the side plate and the connecting block.

[0005] Technical solution: To achieve the above objectives, the present utility model is realized through the following technical solutions: A multi-layer assembled stem cell culture plate, comprising: a culture plate body, with at least two provided, and the culture plate body is used for culturing stem cells; connection blocks, with at least four provided, and the connection blocks are detachably and stably connected to the culture plate body, and the connection blocks are evenly distributed on both sides of the culture plate body; side plates, with two provided, and the side plates are located on both sides of the culture plate body, and the side plates are connected to the culture plate body through the connection blocks, and the side plates are slidably connected to the connection blocks; sleeves, with multiple provided, and the sleeves are stably connected within the connection blocks; sleeve rods, with multiple provided, and one ends of the multiple sleeve rods are respectively located within the sleeves, and the other ends penetrate through the sleeves and are stably connected to the side plates; springs, with multiple provided, and the springs are located within the connection blocks, the springs are stably connected to the periphery of the sleeves, one end of the spring contacts the connection block, and the other end contacts the side plate, and the spring is used to push the connection block; piston blocks, located within the sleeves, and the piston blocks are adapted to the sleeves, and the piston blocks are stably connected to one ends of the sleeve rods; through holes, with multiple provided, and the through holes are opened within the sleeves, the through holes are located at one end of the sleeve away from the other side of the sleeve rod, and the through holes are used to limit the air flow rate entering the sleeves to slow down the sliding speed of the connection blocks, wherein the connection blocks are made of high-strength and corrosion-resistant materials to ensure the stability and reliability during long-term use; the material of the side plates should have good rigidity and wear resistance to ensure the accuracy and stability after multiple sliding operations; the connection between the sleeves and the connection blocks adopts a precise fixing method to ensure that there will be no loosening or displacement during use; the size parameters such as the inner diameter, outer diameter, and length of the sleeves should be precisely set according to the overall design requirements; the springs are selected as high-elasticity coefficient and fatigue-resistant high-quality springs to ensure the stable performance after long-term use; the elastic coefficient and pre-compression amount of the springs should be precisely calculated and adjusted according to actual needs; the piston blocks are made of materials with good sealing performance and have a high matching precision with the sleeves to effectively control the gas flow rate; the aperture and number of the through holes are carefully designed to achieve precise control of the air flow rate, thereby achieving an ideal sliding speed adjustment effect.

[0006] In a further embodiment, multiple chutes are provided, and the chutes are opened within the connection blocks, and the chutes are used to provide spring installation positions; multiple sliders are provided, and the sliders are stably connected to the side plates, the sliders are located within the chutes, the sliders are adapted to the chutes, and the sliders are used to provide the connection positions of the sleeve rods and the side plates, wherein the contact surfaces of the chutes and the sliders are specially treated to reduce friction and wear and improve the service life; the fit tolerance between the chutes and the sliders should be strictly controlled to ensure the sliding accuracy and stability.

[0007] In a further embodiment, a plurality of fixing pins are provided, and the plurality of fixing pins are respectively stably connected to the plurality of connecting blocks. The fixing pins are used to fix the culture plate body. The material of the fixing pins has high strength and good toughness, and is not easily deformed or damaged during installation and disassembly. The distribution position and number of the fixing pins should be reasonably arranged according to the size and weight of the culture plate body to ensure uniform and reliable fixing effect.

[0008] In a further embodiment, a plurality of fixing keys are provided, and the fixing keys are elastically connected to the connecting blocks. The fixing keys are used for connecting and fixing the connecting blocks and the side plates. A plurality of pressing keys are provided, and the pressing keys are slidably connected to the side plates. One end of the pressing key contacts the fixing key, and the pressing key is used to press the fixing key. The operations of the fixing keys and the pressing keys should be light, flexible, and have obvious tactile feedback to facilitate the operator to judge whether the operation is in place. The elastic components of the fixing keys and the pressing keys should pass fatigue tests to ensure good performance under frequent operations.

[0009] In a further embodiment, a limiting groove is further formed in the connecting block. The limiting groove communicates with the sliding groove. A limiting block is stably connected to the sliding block. The limiting block is located in the limiting groove, and the limiting block is adapted to the limiting groove. The design of the limiting groove and the limiting block should consider dust prevention and prevention of foreign objects from entering to ensure smooth sliding. An appropriate margin should be left for the movement space of the limiting block in the limiting groove to avoid jamming caused by manufacturing errors or thermal expansion and contraction.

[0010] In a further embodiment, the contact end of the fixing key and the pressing key is set to be arc-shaped, and the end of the pressing key away from the fixing key is set to be arc-shaped. The arc-shaped design can reduce stress concentration during contact and improve the service life of the components. The curvature radius of the arc should be optimized according to the actual operating force and tactile requirements.

[0011] In a further embodiment, the connecting block is set to be L-shaped to provide an installation position for the culture plate body. The corner of the L-shaped connecting block should be rounded to avoid stress concentration and accidental injury to the operator. The size and angle of the L-shaped connecting block should be reasonably designed according to the shape and weight of the culture plate body to ensure the stability and convenience of installation.

[0012] Beneficial effects: 1. Through the cooperation of the spring, sleeve, sleeve rod and through hole, the effect of providing auxiliary power and controlling the sliding speed during the operation of the culture plate is achieved; the elastic potential energy of the spring provides the driving force for the relative sliding of the side plate and the connecting block, greatly reducing the force required for the operator to manually slide; and the through hole in the sleeve restricts the air flow entering, enabling the movement speed of the piston block to be controlled, thereby slowing down the sliding speed of the connecting block, and at the same time reducing the impact and damage to the structure of the culture plate caused by sudden or uneven force, and extending the service life of the culture plate.

[0013] 2. Through the cooperation between structures such as the fixing key and the pressing key, the effect of convenient, stable connection and quick unlocking between the side plate and the connecting block is achieved; when it is necessary to fix the side plate and the connecting block, the fixing key can reliably maintain the connection state of the two, ensuring that there will be no accidental loosening during use; and when separation is required, the operator only needs to gently press the pressing key to easily release the lock of the fixing key, achieving the purpose of convenient operation and improving work efficiency; in actual use, the cumbersome connection and unlocking steps are avoided, saving operation time. Brief description of the drawings

[0014] In order to more clearly illustrate the technical solutions in the embodiments of the present utility model or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the following drawings are only some embodiments of the present utility model. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0015] Figure 1 It is a schematic structural diagram of the present utility model.

[0016] Figure 2 It is Figure 1 the main sectional structural diagram of

[0017] Figure 3 It is Figure 1 the left sectional structural diagram of

[0018] Figure 4 It is Figure 1 the right sectional structural diagram of

[0019] Figure 5 It is Figure 1 the top sectional structural diagram of

[0020] Figure 6 It is Figure 2 the structural diagram at position A of

[0021] Figure 7 It is Figure 3 the structural diagram at position B of

[0022] Figure 8 is Figure 5 Schematic structural diagram at position C of

[0023] The reference numerals in the figure are: 1, culture plate body; 2, connecting block; 201, chute; 3, side plate; 301, slider; 3011, fixing pin; 4, sleeve; 401, through hole; 5, sleeve rod; 501, piston block; 6, spring; 7, fixing key; 8, pressing key. Detailed implementation manners

[0024] To make the objectives, technical solutions and advantages of the embodiments of the present utility model clearer, the technical solutions in the embodiments of the present utility model will be clearly and completely described. Apparently, the described embodiments are some but not all of the embodiments of the present utility model. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without creative efforts shall fall within the protection scope of the present utility model.

[0025] The embodiments of the present application provide a multi-layer assembled stem cell culture plate, which solves the technical problems of laborious manual operation; and inconvenient connection and operation between the side plate and the connecting block. In actual use, the risk of damage to the culture plate caused by excessive force or improper operation by the operator is reduced, the service life of the culture plate is extended, and the connection operation between the side plate and the connecting block is facilitated.

[0026] To better understand the above technical solutions, the above technical solutions will be described in detail below in conjunction with the accompanying drawings of the specification and specific implementation manners.

[0027] Refer to Figures 1 - 8, A multi-layer assembled stem cell culture plate, comprising: a culture plate body 1, with at least two provided, and the culture plate body 1 is used for culturing stem cells; connecting blocks 2, with at least four provided, and the connecting blocks 2 are detachably and stably connected to the culture plate body 1, and the connecting blocks 2 are evenly distributed on both sides of the culture plate body 1; side plates 3, with two provided, and the side plates 3 are on both sides of the culture plate body 1, and the side plates 3 are connected to the culture plate body 1 through the connecting blocks 2, and the side plates 3 are slidably connected to the connecting blocks 2; sleeves 4, with multiple provided, and the sleeves 4 are stably connected to the connecting blocks 2; sleeve rods 5, with multiple provided, and one ends of the multiple sleeve rods 5 are respectively inside the sleeves 4, and the other ends penetrate through the sleeves 4 and are stably connected to the side plates 3; springs 6, with multiple provided, and the springs 6 are inside the connecting blocks 2, the springs 6 are stably connected to the periphery of the sleeves 4, one end of the springs 6 contacts the connecting blocks 2, and the other end contacts the side plates 3, and the springs 6 are used to push the connecting blocks 2; piston blocks 501, inside the sleeves 4, and the piston blocks 501 are adapted to the sleeves 4, and the piston blocks 501 are stably connected to one ends of the sleeve rods 5; through holes 401, with multiple provided, and the through holes 401 are opened in the sleeves 4, the through holes 401 are at one end of the sleeves 4 away from the other side of the sleeve rods 5, and the through holes 401 are used to limit the air flow entering the sleeves 4 to slow down the sliding speed of the connecting blocks 2.

[0028] Through the cooperation of the culture plate body 1, the connecting blocks 2, the side plates 3, the sleeves 4, the sleeve rods 5, the springs 6, the piston blocks 501 and the through holes 401, the multi-layer assembly and sliding control of the culture plate are realized, and at the same time, the sliding speed of the connecting blocks 2 is slowed down, achieving the purpose of stable and adjustable sliding.

[0029] Chute grooves 201, with multiple provided, and the chute grooves 201 are opened in the connecting blocks 2, and the chute grooves 201 are used to provide the installation positions of the springs 6; sliders 301, with multiple provided, and the sliders 301 are stably connected to the side plates 3, the sliders 301 are inside the chute grooves 201, the sliders 301 are adapted to the chute grooves 201, and the sliders 301 are used to provide the connection positions of the sleeve rods 5 and the side plates 3.

[0030] Through the cooperation of the chute grooves 201 opened in the connecting blocks 2 and the sliders 301 stably connected to the side plates 3 and inside the chute grooves 201, the installation positions of the springs 6 are provided and the connection positions of the sleeve rods 5 and the side plates 3 are determined, ensuring the rationality and stability of the structure.

[0031] Fixed pins 3011, with multiple provided, and the multiple fixed pins 3011 are respectively stably connected to the multiple connecting blocks 2, and the fixed pins 3011 are used to fix the culture plate body 1.

[0032] Through the cooperation of being stably connected to the connecting block 2 by a plurality of fixing pins 3011 respectively, the purpose of firmly fixing the culture plate body 1 is achieved, ensuring safety during use.

[0033] There are a plurality of fixing keys 7, and the fixing keys 7 are elastically connected to the connecting block 2 for connecting and fixing the connecting block 2 and the side plate 3; there are a plurality of pressing keys 8, and the pressing keys 8 are slidably connected to the side plate 3. One end of the pressing key 8 contacts the fixing key 7, and the pressing key 8 is used to press the fixing key 7.

[0034] Through the cooperation of the fixing key 7 being elastically connected to the connecting block 2, the pressing key 8 being slidably connected to the side plate 3 and contacting the fixing key 7, the fixing and separation of the connecting block 2 and the side plate 3 are realized, achieving the effect of convenient operation.

[0035] A limiting groove is further opened in the connecting block 2. The limiting groove communicates with the sliding groove 201. A limiting block is stably connected to the slider 301. The limiting block is located in the limiting groove, and the limiting block is adapted to the limiting groove.

[0036] Through the cooperation of opening a limiting groove communicating with the sliding groove 201 in the connecting block 2 and connecting a limiting block located in the limiting groove on the slider 301, the movement range of the slider 301 is restricted, preventing it from being displaced, and ensuring the accuracy and safety of sliding.

[0037] The contact end of the fixing key 7 and the pressing key 8 is set to be arc-shaped, and the end of the pressing key 8 away from the fixing key 7 is set to be arc-shaped.

[0038] Through the cooperation of setting the contact end of the fixing key 7 and the pressing key 8 and the end of the pressing key 8 away from the fixing key 7 to be arc-shaped, the resistance and wear during contact are reduced, improving the operation feel and the service life of the components.

[0039] The connecting block 2 is set to be L-shaped to provide an installation position for the culture plate body.

[0040] By setting the connecting block 2 to be L-shaped, a suitable installation position is provided for the culture plate body, enhancing the stability of the overall structure.

[0041] During use, first, the culture plate body 1 is installed on the connecting block 2 through the fixing pin 3011 to ensure its stable placement. When it is necessary to extract the culture plate body at the lower part, first press the pressing key 8, which squeezes the fixing key 7, thus releasing the fixation of the fixing key 7 on the side plate 3 and the connecting block 2. At this time, the elastic force of the spring 6 will push the connecting block 2 to slide relative to the side plate 3. During the sliding process, air slowly enters the inside of the sleeve 4 through the through hole 401 on the sleeve 4, thereby slowing down the sliding speed of the connecting block 2, making the sliding of the connecting block 2 stable and controllable, and preventing the slider 301 from disengaging through the cooperation of the limiting block and the limiting groove, ensuring the accuracy of the sliding.

[0042] The required sealing structure, buffer structure, identification structure, etc. mentioned above all belong to the prior art and are non-essential technical features in this application. Therefore, they are not elaborated and drawn in the documents and drawings of this application.

[0043] In summary, compared with the prior art, it has the following beneficial effects: First, through the synergistic effect of the spring, sleeve, sleeve rod, and through hole, the laborious degree of manual operation is greatly reduced, making the operation easier and more efficient. At the same time, it also reduces the risk of damage to the culture plate caused by excessive force or improper operation, and extends the service life of the culture plate. Second, the unique connection and sliding design between the side plate and the connecting block, combined with the ingenious cooperation of the fixing key and the pressing key, solves the problems of inconvenient connection and operation between the side plate and the connecting block in the past, realizes convenient and stable connection and separation, and improves the convenience and accuracy of the operation. Third, the setting of the chute, slider, limiting groove, and limiting block further ensures the accuracy and safety of the sliding. In addition, the design of the L-shaped connecting block provides a stable installation position for the culture plate body.

[0044] The present utility model covers any substitutions, modifications, equivalent methods, and solutions made within the essence and scope of the present utility model. In order to enable the public to have a thorough understanding of the present utility model, specific details are described in detail in the above preferred embodiments of the present utility model. However, those skilled in the art can fully understand the present utility model without these detailed descriptions. In addition, in order to avoid unnecessary confusion to the essence of the present utility model, well-known methods, processes, procedures, components, and circuits, etc. are not described in detail.

[0045] The above description is only a preferred embodiment of the present utility model. It should be noted that for those of ordinary skill in the art, without departing from the principle of the present utility model, several improvements and refinements can be made, and these improvements and refinements should also be regarded as the protection scope of the present utility model.

Claims

1. A multi-layered stem cell culture plate, characterized in that: include: At least two culture plate bodies (1) are provided, and the culture plate bodies (1) are used for culturing stem cells; At least four connecting blocks (2) are provided, and the connecting blocks (2) are detachably and stably connected to the culture plate body (1), and the connecting blocks (2) are evenly distributed on both sides of the culture plate body (1); Two side panels (3) are provided, and the side panels (3) are located on both sides of the culture plate body (1). The side panels (3) are connected to the culture plate body (1) via a connecting block (2), and the side panels (3) are slidably connected to the connecting block (2); A plurality of sleeves (4) are provided, and the sleeves (4) are stably connected to the connection block (2); A plurality of sleeve rods (5) are provided, and one end of each of the sleeve rods (5) is located in the sleeve (4), and the other end passes through the sleeve (4) to be stably connected to the side plate (3); A plurality of springs (6) are provided, and the springs (6) are located in the connection block (2). The springs (6) are stably connected to the periphery of the sleeve (4). One end of the spring (6) contacts the connection block (2), and the other end contacts the side plate (3). The springs (6) are used to push the connection block (2); A piston block (501) is located in the sleeve (4), and the piston block (501) is adapted to the sleeve (4), and the piston block (501) is stably connected to one end of the sleeve rod (5); A plurality of through holes (401) are provided, and the through holes (401) are opened in the sleeve (4). The through holes (401) are located at one end of the sleeve (4) away from the other side of the sleeve rod (5). The through holes (401) are used to limit the air flow entering the sleeve (4) to slow down the sliding speed of the connection block (2).

2. A multi-layer assembled stem cell culture plate according to claim 1, characterized in that: Also includes: A plurality of slide grooves (201) are provided, and the slide grooves (201) are opened in the connecting block (2), and the slide grooves (201) are used to provide installation positions for the springs (6); A plurality of sliders (301) are provided, and the sliders (301) are stably connected to the side panels (3). The sliders (301) are located in the slide grooves (201), and the sliders (301) are adapted to the slide grooves (201). The sliders (301) are used to provide a connection position between the sleeve rod (5) and the side panels (3).

3. The multi-layer assembled stem cell culture plate according to claim 1, characterized in that: Also includes: A plurality of fixing pins (3011) are provided, and the plurality of fixing pins (3011) are respectively and stably connected to the plurality of connecting blocks (2), and the fixing pins (3011) are used to fix the culture plate body (1).

4. The multi-layer assembled stem cell culture plate according to claim 1, characterized in that: Also includes: A plurality of fixing keys (7) are provided, and the fixing keys (7) are elastically connected to the connecting block (2), and the fixing keys (7) are used to connect and fix the connecting block (2) and the side plate (3); A plurality of push keys (8) are provided, and the push keys (8) are slidably connected to the side plate (3), one end of the push key (8) is in contact with the fixed key (7), and the push key (8) is used to press the fixed key (7).

5. The multi-layer assembled stem cell culture plate according to claim 2, characterized in that: A limiting groove is also provided in the connection block (2), the limiting groove is communicated with the slide groove (201), the limiting block is stably connected to the slide block (301), the limiting block is located in the limiting groove, and the limiting block is adapted to the limiting groove.

6. The multi-layer assembled stem cell culture plate according to claim 4, characterized in that: The contact end between the fixed key (7) and the pressing key (8) is arranged in an arc shape, and the end of the pressing key (8) away from the fixed key (7) is arranged in an arc shape.

7. The multi-layer assembled stem cell culture plate according to claim 1, characterized in that: The connection block (2) is configured to be L-shaped to provide a mounting position for the culture plate body.