UV flow cell

By designing disposable, sterile and easy-to-install UV circulation cells, the problem of not being able to ensure a sterile environment and high material costs in the prior art are solved, and the convenient installation and corrosion resistance of the circulation cells are achieved.

CN222979430UActive Publication Date: 2025-06-13TOFFLON HAIWEI (SHANGHAI) BIOSCIENCE CO LTD
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Patent Information

Application Number
CN202421553610.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-07-02
Publication Date
2025-06-13
Estimated Expiration
2034-07-02

AI Technical Summary

Technical Problem

The existing UV circulation cells cannot ensure sterile environmental integrity in single-use production equipment, and the connection structure is not suitable for replacing abandoned flow path components, and the material cost is high.

Method used

A UV circulation cell is designed, adopting a disposable product design, the flow channel is connected to the circulation cell cavity, the lens is fixedly connected through a clamping structure, and the outer periphery of the flow channel is equipped with an anti-slip structure, and the entire circulation cell is not made of metal.

Benefits of technology

Enables sterility in single-use equipment, simplifies installation and replacement of flow path components, reduces material costs and improves corrosion resistance.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model belongs to the field of flow cells, and discloses a UV flow cell. The flow cell comprises a flow cell body, a flow cell cavity and flow channels allowing feed liquid to flow are formed in the flow cell body, the flow channels comprise the first feed liquid flow channel serving as a feed liquid inlet and the second feed liquid flow channel serving as a feed liquid outlet, and the first feed liquid flow channel and the second feed liquid flow channel are coaxially arranged and both communicate with the flow cell cavity; a lens positioning hole for mounting a lens is also formed in the flow cell body; one end of the lens positioning hole is communicated with the flow cell cavity; and the lens is fixedly connected with the lens positioning hole through a clamping structure. And the lens is fixedly connected with the lens positioning hole through a clamping structure, so that the lens is quickly mounted and fixed.
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Description

Technical Field

[0001] The utility model relates to the field of flow cells, and specifically to a UV flow cell. Background Art

[0002] In the field of biopharmaceuticals, the measurement of UV (ultraviolet light) values is involved in many process stages such as purification, fermentation, and inspection of the liquid material to monitor the corresponding properties of the material. The detection instrument for monitoring UV needs to be connected to the production equipment. The working principle of the UV detector is that the ultraviolet light (or ultraviolet light and visible light) emitted from a specific light source (for example, a deuterium lamp) enters the flow cell in the form of a parallel light beam of a single wavelength after passing through a condenser lens, a filter, and a slit. After passing through the detection area, it is irradiated on a photosensitive sensor after passing through another condenser lens. By using the difference in the sample concentration in the mobile phase, the change in light intensity is converted into a change in photocurrent, and after amplification, it is input into a logarithmic converter or a recorder to obtain the spectrum of the change in sample concentration or optical density.

[0003] The following problems exist in the prior art: 1. In a disposable production equipment, it is necessary to ensure the sterility of the components in contact with the liquid material. However, the existing UV flow cells can be disassembled and reused, and the integrity of the sterile environment of the equipment cannot be ensured; 2. The existing UV flow cells, optical fibers, and optical path gaskets are mostly connected by threaded structures, which cannot meet the requirements of replacing and discarding the flow path components; 3. The materials of the existing UV flow cells are basically metals, and the material usage cost is relatively high, which needs to be optimized. Therefore, there is an urgent need in this technical field for a UV flow cell that is suitable for disposable use, easy to install, and conforms to the disposable flow path components. Summary of the Utility Model

[0004] The purpose of the utility model is to solve at least one of the above problems, and provide a UV flow cell, which can be discarded after being used once as a disposable product to ensure the sterility of the components in contact with the liquid material.

[0005] To achieve the above purpose, the utility model provides the following technical solution: A UV flow cell includes a flow cell body. A flow cell cavity and a flow path for the liquid material to flow through are formed inside the flow cell body. The flow path includes a first liquid material flow path as the liquid material inlet and a second liquid material flow path as the liquid material outlet. The first liquid material flow path and the second liquid material flow path are coaxially arranged and are both communicated with the flow cell cavity;

[0006] A lens positioning hole for installing a lens is further provided inside the flow cell body, and one end of the lens positioning hole is communicated with the flow cell cavity;

[0007] The lens is fixedly connected to the lens positioning hole through a clamping structure.

[0008] According to the present utility model, further, the clamping structure includes a snap ring matching the aperture of the lens positioning hole, and the snap ring fixes the lens inside the lens positioning hole; a limiting groove is formed on the inner wall of the lens positioning hole, and an elastic protrusion matching the limiting groove is provided on the outer periphery of the snap ring, and the elastic protrusion is cooperatively fixed with the limiting groove to realize the clamping and fixing of the snap ring and the lens positioning hole.

[0009] According to the present utility model, further, an anti-slip structure is formed on the outer peripheries of the first liquid flow channel and the second liquid flow channel to increase the friction between the flow channel and the external pipeline connected thereto.

[0010] According to the present utility model, further, the limiting groove is a stepped limiting groove.

[0011] According to the present utility model, further, both the flow cell body and the clamping structure are made of non-metallic materials.

[0012] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0013] 1. The lens is fixedly connected to the lens positioning hole through the clamping structure, realizing the quick installation and fixing of the lens.

[0014] 2. The anti-slip structure is provided on the outer periphery of the flow channel, facilitating the connection with the pipeline of the flow path component, reducing the installation fittings, and improving the installation speed.

[0015] 3. The entire flow cell does not contain metal materials, improving its own corrosion resistance. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 is a schematic structural diagram of a UV flow cell of the present utility model;

[0017] Figure 2 is Figure 1 the A-A cross-sectional structural diagram of

[0018] Figure 3 is an exploded view of a UV flow cell of the present utility model;

[0019] Figure 4 is a schematic structural diagram of the snap ring of the present utility model;

[0020] Figure 5 is a schematic diagram of the stepped limiting groove of the present utility model.

[0021] In the figure: 100 - flow cell body, 110 - flow cell cavity, 120 - lens positioning hole, 121 - limiting groove, 200 - first liquid flow channel, 300 - second liquid flow channel, 400 - lens, 500 - snap ring, 510 - elastic protrusion, 600 - toothed anti-slip structure, 700 - sealing ring. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0022] The technical solutions in the embodiments of the present utility model will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without creative efforts shall fall within the protection scope of the present utility model.

[0023] As Figures 1-3 shown, a UV flow cell in an embodiment of the present utility model includes a flow cell body 100. The flow cell body 100 has a top surface facing upward, a bottom surface opposite to the top surface, and opposite left and right side surfaces. A flow cell cavity 110 is formed inside the flow cell body 100. The flow cell cavity 110 communicates with a first liquid flow channel 200 and a second liquid flow channel 300 pointing in opposite directions. The first liquid flow channel 200 penetrates the bottom surface of the flow cell body 100 and serves as an inlet channel for the liquid, and the second liquid flow channel 300 penetrates the top surface of the flow cell body 100 and serves as an outlet channel for the liquid. The liquid enters from the inlet of the first liquid flow channel 200, passes through the flow cell cavity 110, and then is discharged from the outlet of the second liquid flow channel 300 on the other side.

[0024] Lens positioning holes 120 are provided on both the left and right side surfaces of the flow cell body 100. One end of each lens positioning hole 120 communicates with the flow cell cavity 110. A coaxially arranged lens 400 is embedded in the lens positioning hole 120. A snap ring 500 is clamped with the lens positioning hole 120 to limit the position of the lens 400. The external ultraviolet light source irradiates the liquid flowing through the flow cell cavity 110 through the lens 400, and the liquid that has been irradiated and absorbed by the ultraviolet light is then discharged through the second liquid flow channel 200. Preferably, a sealing ring 700 is sleeved on the outer periphery of the lens 400 to improve the installation sealing performance between the lens 400 and the lens positioning hole 120.

[0025] In this embodiment, as Figure 4 and Figure 5As shown, the inner surface of the lens positioning hole 120 has a limiting groove 121. An elastic protrusion 510 is provided on the outer periphery of the snap ring 500 that is snap-fitted with the lens positioning hole 120. The elastic protrusion 510 is engaged with the limiting groove 121 to achieve the snap-fitting and fixation of the snap ring 500 and the lens positioning hole 120. When the snap ring 500 just contacts the lens positioning hole 120, the elastic protrusion 510 is squeezed. As the contact area between the snap ring 500 and the lens positioning hole 120 increases, until the elastic protrusion 510 reaches the limiting groove 121 and loses the external squeezing force, the elastic protrusion 510 is snap-fitted in the limiting groove 121 to achieve the snap connection between the two. Preferably, the elastic protrusion 510 is wedge-shaped, and the limiting groove 121 that cooperates with it is also wedge-shaped. The inclined surface of the wedge-shaped elastic protrusion 510 can play a transitional role, improving the smoothness before its snap connection with the limiting groove 121 and also reducing the resistance. In this embodiment, as Figure 3 shown, a toothed anti-slip structure 600 is formed on the outer peripheries of the first liquid flow channel 200 and the second liquid flow channel 300. The external pipeline is sleeved on the outer periphery of the serrated anti-slip structure 600 to achieve the connection between the pipeline and the corresponding liquid flow channel, and also play a role in preventing the pipeline from slipping. Preferably, the toothed anti-slip structure 600 can be a serrated structure or a toothed structure with smooth intermittent protrusions. It is also possible to set the outer peripheral surfaces of the first liquid flow channel 200 and the second liquid flow channel 300 as surfaces with convex points for anti-friction.

[0026] Among them, the flow cell body 100 and the snap ring 500 are made of non-metallic materials, preferably PPSU or PEEK; the sealing ring 700 is made of silica gel, and the lens 400 is made of quartz. The entire flow cell does not contain metal materials, improving its own corrosion resistance.

[0027] Although the embodiments of the present invention have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principle and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A UV flow cell, comprising a flow cell body, wherein a flow cell cavity and a flow channel for a feed liquid to flow are formed inside the flow cell body, characterized in that: The flow channel includes a first liquid flow channel as a liquid inlet and a second liquid flow channel as a liquid outlet, the first liquid flow channel and the second liquid flow channel are coaxially arranged, and both are connected to the flow cell cavity; A lens positioning hole for installing a lens is also provided inside the circulation cell body, and one end of the lens positioning hole is connected to the circulation cell cavity; The lens is fixedly connected to the lens positioning hole through a clamping structure.

2. A UV flow cell as claimed in claim 1, characterized in that: The clamping structure includes a clamping ring that matches the aperture of the lens positioning hole, and the clamping ring fixes the lens inside the lens positioning hole; a limiting groove is formed on the inner wall of the lens positioning hole, and an elastic protrusion matching the limiting groove is provided on the outer periphery of the clamping ring. The elastic protrusion is fixed with the limiting groove to realize the clamping fixation of the clamping ring and the lens positioning hole.

3. A UV flow cell as claimed in claim 1, characterized in that: The outer peripheries of the first liquid flow channel and the second liquid flow channel are formed with toothed anti-skid structures to increase the friction between the flow channels and external pipelines connected thereto.

4. A UV flow cell as claimed in claim 2, characterized in that: The limiting groove is a stepped limiting groove.

5. A UV flow cell as claimed in claim 1, characterized in that: The circulation pool body and the clamping structure are both made of non-metallic materials.