Ablation catheter

Abstract

The utility model discloses an ablation catheter which comprises a catheter body which comprises a head end electrode section, a transition connection section, a bendable section, a main body section and a handle which are sequentially connected from far to near, and the catheter body is provided with an axially-through guide wire passage; the pull wire system comprises at least two pull wires, the near end of each pull wire is connected with the handle, the far end of each pull wire is connected with the head end electrode section or the transition connection section, and the at least two pull wires can be driven to control the bendable section to bend in different directions; therefore, the ablation catheter can be guided in place in a tissue structure through the guide wire, the operation control difficulty is reduced, the attaching performance can be improved through bending control of the handle, damage to blood vessels is reduced, and the ablation effect is improved.

Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and particularly relates to an ablation catheter that can achieve the placement of a guide wire in place and has controllable bending. Background Art

[0002] Hypertension is one of the main risk factors for cardiovascular diseases. According to statistics, more than 9 million people die from hypertension complications such as myocardial infarction, stroke, and renal failure every year; currently, more than 1 billion people worldwide suffer from hypertension, and 10%-15% of them are refractory hypertension. Although there are currently various safe and effective antihypertensive drugs, for refractory hypertension, it is difficult to control blood pressure within the normal range with antihypertensive drugs. Renal denervation (RDN) is a new interventional treatment technology that has emerged in the past decade. This surgery treats refractory hypertension by blocking the sympathetic afferent and efferent nerve fibers of the renal artery. In clinical trials of refractory hypertension, RDN has shown good application prospects.

[0003] Currently, renal nerve ablation is mostly performed in a "blind" manner, that is, ablation is performed on the entire renal artery. An ideal renal artery ablation should selectively block the renal sympathetic nerves without damaging the innervation of sympathetic nerves to other organs. Therefore, there is an urgent clinical need for an ablation catheter that can accurately mark the distribution of renal nerves on the renal artery and at the same time achieve precise ablation of abnormal renal nerve sites. Stimulating the renal sympathetic nerves can cause increased blood pressure, changes in heart rate, and increased excitability of muscle sympathetic nerves. The RDN procedure can block this overactivation, reduce the activity of the sympathetic nervous system, and achieve the therapeutic effect of reducing blood pressure. By directly stimulating the renal nerves to increase sympathetic nerve tension and thus increase blood pressure and heart rate, it can be expected that renal nerve ablation at this site can more precisely damage renal nerve fibers, thereby improving the clinical efficacy and minimizing unnecessary ablation during the operation to ensure safety.

[0004] Most of the ablation catheters for finding the target point and performing precise ablation are large-head ablation catheters (i.e., using a head electrode at the distal end). Currently, when performing surgery with a large-head ablation catheter, the catheter is placed in place and abutted by controlling the bending through a handle or with the assistance of a sheath. However, this mode is difficult to place in place, especially in tortuous blood vessels, sharp branch angles, and other tissue structures. Currently, although the ablation catheter with an overall exchange design (Over-the-wire, abbreviated as OTW) can rely on a guide wire to be placed in place, when abutting, it basically relies on the elastic rebound of the catheter itself. At this time, the abutting force is uncontrollable. When the abutting force is too large, it is easy to damage the blood vessel, and when the abutting force is too small, the catheter cannot be abutted in place, reducing the ablation effect. Therefore, it is necessary to provide an ablation catheter that can both achieve the placement of a guide wire in place and can be bent by means of a handle, thereby reducing the difficulty of surgical operation and improving the surgical efficiency.

[0005] It should be noted that the information disclosed in the background art section of this application is only intended to deepen the understanding of the general background art of this application, and should not be regarded as an admission or any form of implication that this information constitutes the prior art known to those skilled in the art. Utility Model Content

[0006] The purpose of this application is to provide an ablation catheter that combines the function of wire placement and the function of bending control to solve the problems of difficult placement in tortuous blood vessels and difficult control of the apposition force.

[0007] To achieve the above object, this application provides an ablation catheter, including:

[0008] A catheter body, the catheter body includes a distal electrode section, a transition connection section, a bendable section, a main body section, and a handle that are sequentially connected from far to near, and the catheter body is provided with a wire passage that axially penetrates; and,

[0009] A wire pulling system, the wire pulling system includes at least two wires, the proximal end of each wire is connected to the handle, the distal end of each wire is connected to the distal electrode section or the transition connection section, and at least two wires can be driven to control the bendable section to bend in different directions.

[0010] Optionally, the distal end of the wire passage is flush with the distal end of the distal electrode section; the distal electrode section further includes a perfusion hole, the catheter body is further provided with a fluid passage that axially extends, and the distal end of the fluid passage communicates with the perfusion hole;

[0011] The wire passage is isolated from the fluid passage, or the wire passage is disposed within the fluid passage and forms a gap therebetween, and the proximal end of the gap is sealed.

[0012] Optionally, the wire passage is coaxially disposed within the fluid passage and forms an annular gap therebetween, the proximal end of the annular gap is sealed, and the distal end of the annular gap is sealed or open.

[0013] Optionally, the transition connection section is a single-lumen tube, and the bendable section is a multi-lumen tube;

[0014] The catheter body further includes a fluid tube and a wire tube, and the fluid tube and the wire tube are disposed within the handle, the main body section, and the transition connection section;

[0015] When the guide wire passage is isolated from the fluid passage, a guide wire cavity and an infusion cavity are provided in both the head electrode segment and the bendable segment. The guide wire cavity and the guide wire tube are correspondingly arranged and communicated. The infusion cavity and the fluid tube are correspondingly arranged and communicated. Moreover, the inner cavities of the guide wire cavity and the guide wire tube constitute the guide wire passage, and the inner cavities of the infusion cavity and the fluid tube constitute the fluid passage;

[0016] When the guide wire passage is arranged inside the fluid passage, an infusion cavity is provided in both the head electrode segment and the bendable segment. The infusion cavity and the fluid tube are correspondingly arranged and communicated. The gap between the infusion cavity and the fluid tube and the guide wire tube constitutes the fluid passage, and the inner cavity of the guide wire tube constitutes the guide wire passage.

[0017] Optionally, 4 to 6 cavities are provided in the head electrode segment, and 4 to 5 cavities are provided in the bendable segment.

[0018] Optionally, the ablation catheter further includes: a wire; a wire cavity is provided in the head electrode segment, and the wire cavity houses the wire; when the wire extends from the head electrode segment through the transition connection segment into the bendable segment, it is distributed along the gap between the inner wall of the corresponding cavity in the bendable segment and the outer wall of the fluid tube, and / or along the gap between the inner wall of the corresponding cavity in the bendable segment and the outer wall of the guide wire tube.

[0019] Optionally, when the guide wire passage is arranged inside the fluid passage, the catheter body further includes a guide wire hose, one end of the guide wire hose passes through the proximal side wall of the fluid tube and the gap and is communicated with the inner cavity of the guide wire tube, or the catheter body further includes an infusion hose, one end of the infusion hose is arranged at the proximal end face of the fluid tube and is communicated with the gap.

[0020] Optionally, there are two pull wires, and the distal end of each pull wire is fixed in the proximal pull wire cavity of the head electrode segment, or the distal end of each pull wire is fixed at the distal end of the transition connection segment.

[0021] Optionally, the head electrode segment is linear, annular, claw-shaped or flower-shaped.

[0022] Optionally, the ablation catheter further includes at least one of a temperature sensor and a magnetic positioning sensor; the temperature sensor is installed on the head electrode segment; the magnetic positioning sensor is installed on the head electrode segment or the transition connection segment.

[0023] Compared with the prior art, the ablation catheter of the present application has at least the following advantages:

[0024] In the ablation catheter, a catheter body is included. The catheter body includes a distal electrode section, a transition connection section, a bendable section, a main body section, and a handle that are sequentially connected from far to near. The catheter body is provided with a wire passage that penetrates axially; and a wire pulling system. The wire pulling system includes at least two wires. The proximal end of each wire is connected to the handle, and the distal end of each wire is connected to the distal electrode section or the transition connection section. At least two wires can be driven to control the bendable section to bend in different directions.

[0025] With such a configuration, since the ablation catheter itself reserves a wire passage, during the operation, it is convenient to combine the wire to achieve the placement of the catheter in the tissue structure, thereby reducing the operation difficulty of the operation, improving the operation efficiency, reducing the amount of radiation entering, increasing the safety of the operation. In addition, after the catheter is in place, the bendable section can be bent by means of the handle, improving the catheter's abutting property, reducing the damage to the blood vessel, and improving the ablation effect. Description of the Drawings

[0026] Those of ordinary skill in the art will understand that the provided drawings are used to better understand the present application and do not constitute any limitation to the scope of the present application. Among them:

[0027] Figure 1 is a schematic diagram of the ablation catheter entering the renal artery to perform ablation in the embodiment of the present application;

[0028] Figure 2 is a schematic diagram of the bent shape of the ablation catheter in the embodiment of the present application;

[0029] Figure 3a and Figure 3b are respectively schematic diagrams of guiding the ablation catheter with a wire in the embodiment of the present application; among them, Figure 3a is the state when the ablation catheter is not controlled to bend, Figure 3b is the state when the ablation catheter is controlled to bend;

[0030] Figure 4a is a schematic diagram of inserting a wire into the ablation catheter in vitro in the embodiment of the present application;

[0031] Figure 4b is a schematic diagram of the ablation catheter being inserted into the femoral artery and the wire being sent to the distal end of the renal artery in the embodiment of the present application;

[0032] Figure 4c and Figure 4d are respectively schematic diagrams of the ablation catheter reaching the position along the wire and being controlled to bend and abut by the handle in the embodiment of the present application;

[0033] Figure 5a is the front view of the head electrode in the first embodiment of the present application;

[0034] Figure 5bYes Figure 5a Left view of the head electrode;

[0035] Figure 5c Yes Figure 5a Right view of the head electrode;

[0036] Figure 5d Is the front view of the ablation catheter in Embodiment 1 of the present application when the head electrode section is omitted, where a guide wire hose and a straightener are provided at the proximal end of the handle;

[0037] Figure 5e Is the front view of the ablation catheter in Embodiment 1 of the present application when the head electrode section is omitted, where a perfusion hose and a Luer connector are provided at the proximal end of the handle;

[0038] Figure 6a Is the schematic cross-sectional view of the head electrode in Embodiment 2 of the present application;

[0039] Figure 6b Is the left view of the head electrode in Embodiment 2 of the present application;

[0040] Figure 6c Is the right view of the head electrode in Embodiment 2 of the present application;

[0041] Figure 6d Is the front view of the ablation catheter in Embodiment 2 of the present application when the head electrode section is omitted;

[0042] Figure 7a Is the schematic diagram of the distal end of the ablation catheter in Embodiment 3 of the present application;

[0043] Figure 7b Is the end face view of the bendable section in Embodiment 3 of the present application.

[0044] Among them, the reference numerals in the drawings are explained as follows: 1 - head electrode section; 111 - head electrode; 112 - ring electrode; 2 - transition connection section; 3 - bendable section; 4 - main body section; 5 - handle; 7 - Luer connector; 8 - straightener; 9 - guide wire; 10 - perfusion cavity; 11, 12 - pull wire cavity; 13 - magnetic positioning cavity; 14 - temperature measurement cavity; 15 - wire cavity; 16 - guide wire cavity; 17 - guide wire hose; 18 - perfusion hose; 19 - guide wire tube; 20 - fluid tube; 21 - functional cavity; 1111 - micropore. Detailed implementation manners

[0045] To make the objectives, advantages, and features of the present application clearer, the following further describes the present application in detail with reference to the accompanying drawings and specific embodiments. It should be noted that the drawings are all in a very simplified form and not drawn to scale, and are only used to conveniently and clearly assist in explaining the objectives of the embodiments of the present application. In addition, the structures shown in the drawings are often part of the actual structures. In particular, the emphasis to be shown in each drawing is different, and sometimes different scales are used.

[0046] As used in this application, the singular forms "a", "an", "one" and "the" include plural referents, the term "or" is generally used in the sense of including "and / or", the term "several" is generally used in the sense of including "at least one", the term "at least two" is generally used in the sense of including "two or more", in addition, the terms "first", "second", "third" are for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. Thus, features defined with "first", "second", "third" may explicitly or implicitly include one or at least two of such features, "one end" and "the other end" as well as "proximal end" and "distal end" generally refer to two corresponding parts, which include not only the endpoints. In this article, the distal end refers to the end close to the patient, and the proximal end refers to the end close to the operator. In addition, as used in this application, "mounted", "connected", "coupled", an element "disposed" on another element should be understood in a broad sense, usually only indicating that there is a connection, coupling, cooperation or transmission relationship between the two elements, and the two elements can be directly or indirectly connected, coupled, cooperated or transmitted through an intermediate element, rather than being construed as indicating or implying the spatial position relationship between the two elements, that is, an element can be in any position such as inside, outside, above, below or on one side of another element, unless the content clearly indicates otherwise. For those of ordinary skill in the art, the specific meanings of the above terms in this application can be understood according to specific circumstances. In addition, directional terms such as above, below, up, down, upward, downward, left, right, etc. are used relative to the exemplary embodiments as shown in the figures, the upward or upward direction is towards the top of the corresponding figure, and the downward or downward direction is towards the bottom of the corresponding figure.

[0047] The core idea of this application is to provide an ablation catheter that can achieve both guide wire guidance and multi-directional bending control, so that the ablation catheter can easily enter various vascular tissues, reduce the surgical difficulty, improve the surgical efficiency, and shorten the learning curve. At the same time, the core idea of this application is also to provide a multifunctional catheter manufacturing method that is generally applicable, low-cost, and can be made from locally available materials.

[0048] The ablation catheter of this application can be easily guided by a guide wire to reach the target position in the tissue structure, reducing the surgical manipulation difficulty. It can also improve the apposition by controlling the bending with the handle, reduce the damage to the blood vessel, improve the ablation effect, increase the safety and effectiveness of ablation, especially suitable for reaching the target position in the abnormal tissue structure, and can greatly reduce the surgical manipulation difficulty.

[0049] The ablation catheter of the present application can maintain the outer diameter of the original catheter, minimize changes to the structural layout of the original catheter, and not affect the performance and / or functions of the original catheter. Based on the original structure, the ablation catheter of the present application can integrate a guide wire and bend control, and also take into account electrode stimulation ablation, and even multiple functions such as temperature measurement, magnetic positioning, and perfusion cooling.

[0050] The outer diameter of the ablation catheter of the present application is preferably 4F to 8F (about 1.32 mm to 2.64 mm), and more preferably 6F (about 2.0 mm).

[0051] Moreover, although the innovation of the present application originates from renal ablation, those skilled in the art can understand that the present application can also be applied to ablation in different parts such as cardiac ablation and bronchial ablation, and there is no limitation in this regard.

[0052] The following description is made with reference to the accompanying drawings. Although the stimulation ablation of the renal artery is described below, those skilled in the art should be able to modify the following description and apply the description to the stimulation ablation of non-renal arteries with appropriate modifications in details.

[0053] Figure 1 It is a schematic diagram of the scenario where the ablation catheter in the embodiment of the present application enters the renal artery through the puncture sheath via the femoral artery and then performs electrical stimulation or ablation. Please refer to Figure 1 and in combination with Figures 4a to 4d In this application scenario, the ablation catheter can cross the renal artery orifice and the vascular tortuous part with the help of the guide wire 9 and enter the renal artery for stimulation or ablation.

[0054] Specifically, the ablation catheter includes a catheter body, and the catheter body includes a head electrode segment 1, a transition connection segment 2, a bendable segment 3, a main body segment 4, and a handle 5 that are sequentially connected from far to near. Generally, the transition connection segment 2 is a single-lumen tube, and the bendable segment 3 is a multi-lumen tube, but it is not limited thereto in practice. The number of cavities in the bendable segment 3 can be adjusted according to the actual situation. Optionally, 4 to 5 cavities are provided in the bendable segment 3.

[0055] Among them, the head electrode segment 1 includes electrodes, and the electrodes are used to abut against the target tissue to perform ablation or signal extraction. In this embodiment, the head electrode 111 and the ring electrode 112 are taken as examples. Any one of the electrodes can be used to apply energy for stimulation or ablation. The stimulation types include monopolar stimulation and bipolar stimulation, and the ablation types also include two forms of monopolar ablation and bipolar ablation. The electrodes can be one or more. When the number of electrodes is more than one, the electrodes are connected through an insulating member and electrically isolated. The electrodes can be made of various conductive materials. For example, optionally, conductive materials such as platinum-iridium alloy, stainless steel, and gold can be used. Preferably, at least one electrode is made of a radiopaque material, and the radiopaque material is not limited to platinum-iridium alloy.

[0056] It should be noted that the specific shape of the head electrode segment 1 of the present application is not limited. For example, the head electrode segment 1 can be in various shapes that require in-place operations, such as a straight shape, a circular shape, a claw shape, or a flower shape, etc. In the figure, the head electrode segment 1 in a straight shape or a circular shape is mainly described, but those skilled in the art should know that the following description can be modified and the description can be applied to the head electrode segment 1 of other shapes after appropriate modifications in details.

[0057] Furthermore, to achieve the core idea of the present application, on the one hand, the catheter body is provided with an axially penetrating guide wire passage (not labeled). The guide wire passage extends from the head electrode segment 1, the transition connection segment 2, the bendable segment 3, the main body segment 4, and continues to the handle 5, thus forming an overall exchangeable design. In this way, the guide wire 9 enters the body along the reserved guide wire passage of the ablation catheter, guiding the catheter through tortuous vascular tissue sites and reaching various stimulation and ablation sites. For example, the ablation catheter of the present application can selectively ablate and block renal artery sympathetic afferent and efferent nerve fibers to achieve the purpose of treating hypertension, and can also perform ablation in the electrophysiology field. The ablation catheter of the present application can provide doctors with more surgical operation options. It can either select sheath-assisted placement of the ablation catheter or, without using a sheath, place the ablation catheter through the guidance of the guide wire 9, which increases the flexibility of surgical operations and indirectly reduces the surgical difficulty.

[0058] To achieve the core idea of the present application, on the other hand, the ablation catheter further includes a wire pulling system. The wire pulling system includes at least two wires (not shown). The proximal end of each wire is connected to the handle 5, and the distal end of each wire sequentially passes through the main body segment 4, the bendable segment 3, and the transition connection segment 2 and then is connected to the head electrode segment 1 or the transition connection segment 2.

[0059] It should be noted that the distal end of the wire can be directly connected to the proximal end of the head electrode segment 1, or the distal end of the wire is directly connected to the distal end of the transition connection segment 2. In short, the distal end of the wire needs to be fixed at the proximal end of the head electrode segment 1 and the distal end of the transition connection segment 2, and when arranging the wires in the catheter body, it is necessary to ensure that the wires do not affect each other and do not interfere with each other. If the distal end of the wire is directly connected to the proximal end of the head electrode segment 1, it is preferably to set a wire cavity at the proximal end of the head electrode segment 1 to fix the wire, and the wire cavities are arranged in one-to-one correspondence with the wires.

[0060] Based on this, when bending control is required, at least two of the wires can be driven by the handle 5 to control the bendable segment 3 to drive the head electrode segment 1 to bend in different directions.

[0061] The ablation catheter of the present application can at least achieve two-way bending control, and even achieve bending control in more directions, and can achieve bending control in various shapes, such as abnormal bending in S shape, Z shape, etc., or bending control in relatively regular shapes, such as C shape bending. The specific bending control form and bending angle are not limited.

[0062] Therefore, the ablation catheter of the present application can also utilize the bending control function to precisely control the bending shape of the distal electrode segment 1, improve the apposition performance, increase the apposition efficiency, and reduce the difficulty of apposition control. And in some application scenarios, through bending control, it is also beneficial for the distal end of the ablation catheter to smoothly cross the vascular bifurcation to reach the target position (such as Figure 4c ), further reducing the difficulty of reaching the target position.

[0063] Figure 2 In the typical example given, the ablation catheter of the present application can achieve bidirectional deflection. Specifically, two pull wires are provided. When the operating handle 5 drives one of the pull wires to move, the bendable section 3 can be controlled to bend relative to the main body section 4 in a preset direction. When the operating handle 5 drives the other pull wire to move, the bendable section 3 can be controlled to bend relative to the main body section 4 in the opposite direction. The bending control angle can reach 180°, and it can pass through various vascular orifices and reach the target position smoothly, and even can replace the function of the sheath. It should be noted that the bending control shape and the bending control angle can be changed according to actual needs.

[0064] The present application does not limit the specific installation method of the pull wires. For example, the distal end of each pull wire is crimped or welded to a metal tube, such as a stainless steel tube, etc., and then the distal metal tube of each pull wire is welded or crimped at a suitable position. For example, in some embodiments, the stainless steel tube is directly welded or crimped in the pull wire cavity, or welded or crimped in the transition connection section 2. Each pull wire passes straight through the transition connection section 2, the bendable section 3, and the main body section 4, and finally the proximal end is fixed on the handle 5. Actually, the pull wire can be any linear body with elasticity, certain flexibility and certain strength, and the specific material and shape are not limited. Optionally, a circular pull wire is used. In addition, when the pull wire is connected to the handle 5, a bending control knob can be provided on the handle 5. By rotating the bending control knob, the pull wire can be pulled, and one bending control knob can control two pull wires at the same time, which is convenient for operation.

[0065] Furthermore, for the sake of easy understanding, Figure 3a and Figure 3b the operation schematic diagrams of the ablation catheter combined with the guide wire 9 to reach the target position are also schematically given. As Figure 3a and Figure 3b shown, for abnormal tissue structures with curved shapes and sharp branch angles (specifically tortuous blood vessels and bifurcated blood vessels), since a guide wire passage is reserved in the ablation catheter of the present application, during the operation, the ablation catheter can be conveniently combined with the guide wire 9 to reach the target position in the abnormal tissue structure, effectively reducing the difficulty of the operation, shortening the learning curve, improving the operation efficiency, and at the same time reducing the radiation exposure and increasing the safety of the operation.

[0066] The surgical procedure of transcatheter renal sympathetic denervation is generally as follows: Before placing the ablation catheter, puncture is first performed. Femoral artery puncture is carried out medial to the inferior inguinal ligament. After seeing blood return, the guide wire 9 is quickly sent into the femoral artery from the puncture needle, and the guide wire 9 enters the abdominal aorta through the femoral artery. After the guide wire 9 is in place, the puncture needle is withdrawn, and the puncture sheath with a dilator is inserted into the femoral artery. After the distal end of the puncture sheath enters the abdominal aorta, the dilator and the guide wire 9 are removed, and the puncture sheath remains in place, and abdominal aortic angiography is performed. It should be noted that the above puncture process is carried out according to the normal operation procedure. Whether the guide wire 9 and the sheath are needed for assisting when inserting the ablation catheter after puncture can be determined by the doctor according to the actual situation. After puncture and angiography are completed, the ablation catheter is placed. In the embodiments of the present application, for the placement process of the ablation catheter, please refer to Figures 4a to 4d as shown.

[0067] First, as Figure 4a shown, outside the body, the guide wire 9 is sent into the ablation catheter along the guide wire passage of the ablation catheter, but the distal end of the guide wire 9 does not leak out of the guide wire passage;

[0068] Then, as Figure 4b shown, the ablation catheter is sent into the puncture sheath. At this time, the guide wire 9 is pushed to the distal end of the renal artery;

[0069] Furthermore, as Figure 4c shown, the ablation catheter is made to cross the renal artery ostium and the vascular tortuous part along the guide wire 9 and enter the renal artery;

[0070] After reaching the target position, as Figure 4d shown, after withdrawing the guide wire 9 to the main body section 4 of the ablation catheter, the ablation catheter can be bent to achieve the apposition of the distal electrode section 1, and then stimulation and selective ablation treatment are carried out. For example, stimulation and ablation are carried out from the distal branches of the renal artery to the proximal main trunk, or from the proximal main trunk of the renal artery to the distal branches of the renal artery. For each operation, the above steps of reaching the position, apposition, stimulation, selective ablation, etc. are repeated.

[0071] It can be seen from the above steps that the ablation catheter of the present application can smoothly cross the renal artery ostium and enter the renal artery vessel without the assistance of a sheath, which can better meet the operation and use requirements of electrophysiological catheters.

[0072] On the other hand, for the stimulation and ablation treatment, it is also necessary to reduce the damage of heat to the target tissue. Therefore, the ablation catheter of the present application preferably also has a perfusion and cooling function. Thus, in some embodiments of the present application, the distal electrode section 1 further includes perfusion holes (see Figure 5aThe specific number of the perfusion holes is not limited. At the same time, the catheter body is also provided with an axially extending fluid passage, and the distal end of the fluid passage is connected to the perfusion holes. The proximal end of the fluid passage is used to connect the perfusion device, and then input the cooling medium. The cooling medium is generally selected from physiological saline, but it is not limited to this. The perfusion device injects the cooling medium into the fluid passage, and finally the cooling medium flows out through the perfusion hole at the head end electrode segment 1 to achieve cooling of the target tissue.

[0073] In some embodiments of the present application, the distal end of the fluid passage does not penetrate the head end electrode segment 1, that is, the distal end of the fluid passage is blocked, and only circumferential perfusion cooling is achieved.

[0074] In other embodiments of the present application, the distal end of the fluid passage passes through the head end electrode segment 1, so that the distal end of the fluid passage is in an open state, thereby achieving circumferential perfusion cooling and end surface perfusion cooling.

[0075] From the perspective of the setting method, there are two relative positions of the fluid passage and the guidewire passage: the first method is that the guidewire passage and the fluid passage are isolated from each other, that is, the two are separated; the second method is that the guidewire passage is set in the fluid passage, and a gap is formed between the guidewire passage and the fluid passage, and the proximal end of the gap is sealed, which can be an annular gap or a non-annular gap. The specific setting method can be set according to the use requirements of the treatment scenario. For example, in a treatment scenario where the perfusion flow rate does not need to be too large, the second method can be selected, and in a treatment scenario where the perfusion flow rate needs to be larger, the first method can be selected.

[0076] However, it should be noted that the distal end of the guidewire pathway is preferably flush with the distal end of the head electrode segment 1 and does not protrude forward to avoid damaging the tissue. The guidewire pathway is suitable for guidewires of various specifications, such as optional 0.014-inch guidewires. Since hydrophilic materials are prone to sliding when exposed to water and are not easy to fix at the abutment point, the guidewire tip is preferably made of a non-hydrophilic material, such as PTFE (polytetrafluoroethylene) or other non-hydrophilic materials to make the guidewire tip, or the guidewire tip is coated with a non-hydrophilic coating. The inner wall of the guidewire pathway can also be provided with a material with good lubricity to reduce the friction between the guidewire pathway and the guidewire 9, which helps to put the guidewire in place.

[0077] Preferably, the guide wire passage is coaxially disposed within the fluid passage, and an annular gap is formed between the guide wire passage and the fluid passage. The proximal end of the annular gap is hermetically sealed, and the distal end of the annular gap is hermetically sealed or open. Such a setting is conducive to forming a guide wire passage with good smoothness, avoiding jamming and blockage at each joint when the guide wire 9 is retracted or pushed. In addition, there is almost no blocked area in the annular gap, avoiding problems such as affecting perfusion and excessive back pressure. More appropriately, the distal end of the annular gap is hermetically sealed, so that the cooling medium can only flow out through the perfusion holes to achieve circumferential perfusion cooling, and the safety is better.

[0078] It should also be noted that both the guide wire passage and the fluid passage in the catheter body are divided into two parts. One part is a cavity, and the other part is an inner cavity passage built by a polymer tube. Cavities are directly provided in both the head electrode section 1 and the bendable section 3, while polymer tubes are provided in the transition connection section 2, the main body section 4, and the handle 5 to construct the guide wire passage and the fluid passage. Specifically, both the guide wire passage and the fluid passage are formed by sequentially connecting multiple parts, rather than being integrally formed.

[0079] Return to reference Figure 1 In some embodiments of the present application, the catheter body further includes a guide wire tube 19 and a fluid tube 20. Both the guide wire tube 19 and the fluid tube 20 are polymer tubes, and the specific material is not limited. Thus, both the guide wire tube 19 and the fluid tube 20 are provided in the handle 5, the main body section 4, and the transition connection section 2. Specifically, both the guide wire tube 19 and the fluid tube 20 sequentially pass through the handle 5 and the main body section 4 from the proximal end of the handle 5 and extend to the bendable section 3, and are correspondingly disposed with the cavities in the bendable section 3. In addition, another part of the guide wire tube 19 and the fluid tube 20 are continuously provided in the transition connection section 2, and the guide wire tube 19 and the fluid tube 20 in the transition connection section 2 further extend into the head electrode section 1 and are correspondingly disposed with the cavities in the head electrode section 1.

[0080] Specifically, when the guide wire passageway is isolated from the fluid passageway, the guide wire cavity 16 and the perfusion cavity 10 which are isolated from each other are arranged in both the distal electrode segment 1 and the flexible segment 3. The guide wire cavity 16 and the guide wire tube 19 are correspondingly arranged and communicated. The perfusion cavity 10 and the fluid tube 20 are correspondingly arranged and communicated. Moreover, the inner cavities of the guide wire cavity 16 and the guide wire tube 19 constitute the guide wire passageway, and the inner cavities of the perfusion cavity 10 and the fluid tube 20 constitute the fluid passageway. In this embodiment, the guide wire cavity 16 needs to penetrate through the distal electrode segment 1. Thus, for the guide wire passageway, the first part is the self-cavity of the distal electrode segment 1, the second part is a polymer tube which passes through the proximal end of the distal electrode segment 1, through the transition connection segment 2, and reaches the distal end of the flexible segment 3, the third part is the self-cavity of the flexible segment 3, and the fourth part is also a polymer tube which extends from the proximal end of the flexible segment 3 along the main body segment 4 to the handle 5. The setting mode of the fluid passageway is similar to that of the guide wire passageway. In a further improvement, to ensure the smoothness and unobstructedness of the guide wire 9 in the guide wire passageway, the distal end of the polymer tube forming the guide wire passageway is subjected to a tapered stretching process, and an appropriate amount of lubricant is applied when gluing and fixing at the joints of each part to achieve a smooth transition at the joint positions.

[0081] On the contrary, when the guide wire passageway is arranged inside the fluid passageway, only the perfusion cavity 10 needs to be arranged in both the distal electrode segment 1 and the flexible segment 3. The perfusion cavity 10 and the fluid tube 20 are correspondingly arranged and communicated. The gap between the perfusion cavity 10 and the fluid tube 20 and the guide wire tube 19 constitutes the fluid passageway, and the inner cavity of the guide wire tube 19 directly constitutes the guide wire passageway. At this time, the perfusion cavity 10 needs to penetrate through the distal electrode segment 1 so that the guide wire tube 19 can smoothly penetrate through the entire distal electrode segment 1.

[0082] Optionally, a Luer connector 7 is arranged on the proximal end of the fluid tube 20 to facilitate external connection of a perfusion device. Optionally, a straightener 8 is arranged on the proximal end of the guide wire tube 19, and the inner diameter of the straightener 8 is larger than the outer diameter of the guide wire tube 19. The function of the straightener 8 is to facilitate the doctor to quickly and accurately insert the guide wire 9 into the guide wire tube 19. In other embodiments, the straightener 8 can also be replaced with a valve, and this is not limited.

[0083] Optionally, the ablation catheter further includes a temperature sensor which is installed on the distal electrode segment 1. The temperature sensor is mainly used to measure the temperature during electrode ablation to avoid burning tissues due to excessive temperature. The temperature sensor is usually fixed inside the distal electrode segment 1 and mainly adopts the form of a thermocouple.

[0084] Optionally, the ablation catheter further includes a magnetic positioning sensor which is installed on the distal electrode segment 1 or the transition connection segment 2.

[0085] In a preferred embodiment of the present application, the ablation catheter of the present application integrates wire placement, stimulation, ablation, and three-dimensional positioning, enabling immediate ablation of the calibrated nerve target, reducing the operation difficulty of catheter placement, improving accuracy, and shortening the learning curve of the operator. On this basis, the ablation catheter of the present application can also take into account temperature measurement and perfusion cooling functions.

[0086] Furthermore, the ablation catheter described in the present application further includes various wires, at least including electrode wires, and further may include wires of a temperature sensor. The electrode wires and the wires of the temperature sensor both extend from the head end electrode section 1 to the handle 5 and are electrically connected to the corresponding interfaces at the handle 5, thereby realizing electrical stimulation and radiofrequency energy ablation, as well as temperature monitoring. Correspondingly, the head end electrode section 1 is provided with a wire cavity 15 (see Figure 5c , Figure 6b , Figure 6c , Figure 7b ), and the wire cavity 15 houses the wires.

[0087] Optionally, when the wire extends from the head end electrode section 1 through the transition connection section 2 to the bendable section 3, the wire is distributed along the gap between the inner wall of the corresponding cavity in the bendable section 3 and the outer wall of the fluid tube 20, or the wire is distributed along the gap between the inner wall of the corresponding cavity in the bendable section 3 and the outer wall of the wire guide tube 19. In other words, there is no need to provide a dedicated wire cavity in the bendable section 3, saving space.

[0088] Preferably, 4 to 6 cavities are provided in the head end electrode section 1, and 4 to 5 cavities are provided in the bendable section 3. The following is a demonstration.

[0089] In some exemplary embodiments, 6 cavities are provided in the head end electrode section 1, including 2 mutually isolated wire pulling cavities 11, 12, 1 temperature measurement cavity 14, 1 wire cavity 15, 1 magnetic positioning cavity 13, and 1 perfusion cavity 10. This part of the content will be introduced in detail in Embodiment 1 below. For details, please refer to Figure 5b and Figure 5c .

[0090] In some other exemplary embodiments, 6 cavities are provided in the head end electrode section 1, including 2 mutually isolated wire pulling cavities 11, 12, 1 temperature measurement cavity 14, 1 wire cavity 15, 1 perfusion cavity 10, and 1 wire guide cavity 16. This part of the content will be further described in Embodiment 2 below. For details, please refer to Figures 6a to 6c .

[0091] In other exemplary embodiments, 4 cavities are provided in the head end electrode section 1, including 1 mutually isolated perfusion cavity 10, 1 wire guide cavity 16, 1 wire cavity 15, and 1 functional cavity 21. This part of the content will be further described in Embodiment 3 below. For details, see Figures 7a to 7b .

[0092] It should be understood that the wire drawing cavities 11 and 12 are used to fix the wire, the temperature measuring cavity 14 is used to accommodate the temperature sensor and its wire, the magnetic positioning cavity 13 is used to accommodate the magnetic positioning sensor, and the function cavity 21 is mainly used to place accessories such as shaping wires and wire control loops for adjusting the shape and size of the head electrode section 1.

[0093] Generally speaking, when manufacturing the head electrode section 1 of this application, the original structural design of the head electrode section 1 can be basically maintained unchanged, and only appropriate adjustments are required, thereby reducing the development cost.

[0094] In addition, there are no special limitations on the structure of the main body section 4. The main body section 4 is a slender tube body for docking the bendable section 3 and the handle 5. The main body section 4 should have the functions of supporting the tube body, preventing deformation, and enabling the catheter torque to be transmitted proportionally. Optionally, the main body section 4 includes braided wires, which are beneficial to enhancing the strength of the main body section 4. The braided wires can be selected as stainless steel (such as SS304 stainless steel) or materials with similar effects or functions. The braided wires can be circular braided wires or braided wires of other shapes. More preferably, double-strand braiding is adopted.

[0095] For better understanding, the following further describes the structure of the ablation catheter proposed in this application in conjunction with several specific embodiments.

[0096]

Embodiment 1

[0097] Please refer to Figures 5a to 5e , in the ablation catheter provided by the first embodiment of this application, the head electrode section 1 is in a straight shape and includes a head electrode 111 and a ring electrode 112 (see Figure 1 ).

[0098] Please refer to Figure 5a , a large number of micropores 1111 are provided on the surface of the head electrode 111. The micropores 1111 are perfusion holes, such as micropore designs of 6 holes, 55 holes, or 66 holes, etc. In this embodiment, 55 micropores are taken as an example. These micropores 1111 have an appropriate pore size, such as a pore size of about 0.1 mm. The numerous micropores 1111 on the surface of the head electrode 111 can achieve uniform coverage of the water film, while achieving good cooling, the saline perfusion volume can be reduced, and the physical burden on the patient can be alleviated.

[0099] Another reference Figure 5b and Figure 5c , there are also 6 cavities isolated from each other in the head electrode 111, specifically as follows:

[0100] (1) Two symmetrically distributed wire drawing cavities 11 and 12, and the two wire drawing cavities 11 and 12 are connected to two wires in a one-to-one correspondence to achieve two-way bending control;

[0101] (2) One magnetic positioning cavity 13 that houses a magnetic positioning sensor to achieve three-dimensional magnetic positioning, thereby tracking the position of the distal end of the catheter;

[0102] (3) One temperature measurement cavity 14 that houses a temperature sensor and its wires to monitor the temperature of the electrode and tissue;

[0103] (4) One wire cavity 15 that houses the electrode wire;

[0104] (6) One perfusion cavity 10, with a guide wire cavity 16 placed inside the perfusion cavity 10. Taking saline perfusion as an example, the saline flows between the inner wall of the perfusion cavity 10 and the outer wall of the guide wire cavity 16.

[0105] In this way, there is no need to re-develop the head electrode 111, reducing the manufacturing cost. Thus, in the first embodiment of the present application, the head electrode 111 integrates many functions such as two-way bending control, guide wire positioning, magnetic positioning, perfusion cooling, and temperature measurement, and can more conveniently pass through the abnormal tissue structure to reach the ablation target position, reducing the difficulty of surgical operation.

[0106] During specific assembly, electrical isolation is achieved by connecting the head electrode 111 and the ring electrode 112 through an insulating part. It can be understood that the head electrode 111, the insulating part, the ring electrode 112, the transition connection section 2, and the bendable section 3 are connected in sequence from far to near. The proximal end of the transition connection section 2 is connected to the distal end of the bendable section 3, and the connection method can be bonding with glue, such as epoxy glue or glue with similar equivalent efficacy. The ring electrode 112 can only have the function of conducting electricity, or can also have functions such as temperature measurement, perfusion, and magnetic and electrical positioning, depending on requirements. For this, the present application does not describe it in detail.

[0107] In the first embodiment of the present application, the guide wire cavity 16 can be integrally formed during the processing of the head electrode 111, or the guide wire cavity 16 can be separately provided. Specifically: directly form the guide wire cavity 16 in the perfusion cavity 10 by overlapping a polymer tube. The polymer tube extends from the head electrode 111 to the distal end of the bendable section 3, and the polymer tube is fixed with glue at the transition connection section 2. In addition, functional components such as the temperature sensor, magnetic positioning sensor, and wires are assembled in the corresponding cavities of the head electrode 111 by welding or bonding, and finally extend to the handle 5.

[0108] Then, referring again to Figure 4d , when the ablation catheter of the present application enters the mouth of the renal artery from the abdominal aorta, Figure 2The shown bend helps to find the entrance and reduces the difficulty of inserting the ablation catheter. In addition, when advancing the ablation catheter from the proximal end to the distal end of the renal artery, due to the presence of curved structures such as S-shaped in the blood vessel, it is difficult to advance the ablation catheter only by controlling the bend. Therefore, a guide wire lumen 16 is provided in the perfusion lumen 10. The guide wire lumen 16 allows the guide wire 9 to pass through, so that the ablation catheter can travel along the guide wire 9. Through the guidance of the guide wire 9, the ablation catheter can be easily positioned in such tortuous blood vessels, reducing the manipulation difficulty.

[0109] Further, as Figure 5d shown, in this embodiment, the catheter body further includes a guide wire hose 17. One end of the guide wire hose 17 passes through the proximal side wall of the fluid tube 20 (with a hole punched) and the gap between the fluid tube 20 and the guide wire tube 19 and communicates with the inner cavity of the guide wire tube 19. Accordingly, the guide wire 9 can be directly inserted from the port of the straightener 8. Through the guiding action of the guide wire 9, the ablation catheter is extended along the path of the guide wire 9 to the target point. At the same time, saline is injected into the gap between the fluid tube 20 and the guide wire tube 19 from the port of the Luer connector 7, reaches the head electrode section 1 along the gap, and then flows out from numerous micropores 1111.

[0110] As Figure 5e shown, in another embodiment, the catheter body further includes a perfusion hose 18. Instead of the guide wire hose 17, one end of the perfusion hose 18 is directly arranged at the proximal end face of the fluid tube 20 and communicates with the gap between the fluid tube 20 and the guide wire tube 19, that is, the perfusion hose 18 is installed between the fluid tube 20 and the guide wire tube 19. Specifically, the perfusion hose 18 is arranged at the proximal end face of the guide wire tube 19 and the fluid tube 20, and the gap between the guide wire tube 19 and the fluid tube 20 at the proximal end face is sealed with glue to prevent the backflow of saline. In this way, the straightener 8 is directly glued to the proximal end of the guide wire tube 19 to insert the guide wire 9, and the saline is directly injected into the gap between the fluid tube 20 and the guide wire tube 19 from the port of the Luer connector 7.

[0111]

Embodiment Two

[0112] Please refer to Figures 6a to 6d , in the ablation catheter provided in the second embodiment of the present application, the structure of the head electrode 111 is basically the same as that of the head electrode 111 in the first embodiment. The difference is that in the second embodiment of the present application, the perfusion lumen 10 and the guide wire lumen 16 are separated.

[0113] More specifically, the head electrode 111 is provided with 6 mutually isolated cavities, as follows: (1) 2 wire pulling cavities 11 and 12; (2) 1 temperature measuring cavity 14; (3) 1 wire guiding cavity 15; (4) 1 perfusion cavity 10; (5) 1 guide wire cavity 16. Among them, the perfusion cavity 10 does not penetrate the head electrode 111, so Figure 6bThe distal end of the perfusion cavity 10 is blocked as indicated by a dashed line, and the guide wire cavity 16 penetrates through the head electrode 111. With this arrangement, there is no need to re-develop the head electrode 111, reducing the development cost.

[0114] In this embodiment, since the guide wire cavity 16 and the perfusion cavity 10 are separated, saline does not flow out from the distal end of the guide wire cavity 16 during perfusion, which does not affect the perfusion and cooling function of the small holes on the surface of the head electrode 111. It is beneficial to control the perfusion flow within a safe range, without increasing the patient's physical burden, ensuring safety.

[0115] Another difference from Embodiment 1 is that in the ablation catheter of Embodiment 2, the magnetic positioning sensor needs to be moved backward to the transition connection section 2 to avoid setting a magnetic positioning cavity 13 on the head electrode 111, without increasing the size of the original structure at the distal end of the catheter and without affecting the function of the original catheter. Then, there is a difference in the installation distance between the position of the magnetic positioning sensor and the position of the head electrode 111 in the axial direction (Z coordinate direction), and the position of the head electrode 111 can be calculated by compensating in the positioning algorithm at the device end.

[0116] Here, the assembly method of the head electrode section 1, the transition connection section 2, the bendable section 3, the main body section 4, and the handle 5 is the same as that described in the above embodiment, and will not be elaborated.

[0117] Finally, referring to Figure 6d As shown, in Embodiment 2 of the present application, the guide wire tube 19 and the fluid tube 20 extending from the proximal end of the handle 5 are separated from each other. The guide wire 9 can be directly fed into the port of the straightener 8, and saline is directly injected into the fluid tube 20 from the port of the Luer connector 7. In this case, there is no need to add a hose, which can further reduce the development cost.

[0118]

Embodiment 3

[0119] Please refer to Figures 7a to 7b , in the ablation catheter provided in Embodiment 3 of the present application, the head electrode section 1 is in a ring shape (i.e., a ring). Specifically, the ablation catheter is sequentially provided with a head electrode section 1, a transition connection section 2, a bendable section 3, a main body section 4, and a handle (not shown) from far to near. When the head electrode section 1 is a ring, it includes one or more electrodes, and the electrodes are loaded on the tube body of the head electrode section 1, and the tube body is a polymer tube material, such as polymer materials like pebax. Among them, the transition connection section 2 is a single-lumen tube, and the bendable section 3 is a multi-lumen tube. In this embodiment, the head electrode section 1 is provided with 4 cavities, and the bendable section 3 is provided with 5 cavities.

[0120] In the ring 23, the 4 cavities are respectively 1 guide wire cavity 16, 1 perfusion cavity 10, 1 wire cavity 15, and 1 function cavity 21, and the function cavity 21 accommodates a shaping wire and a coil control wire.

[0121] Now taking the bendable section 3 as an example, asFigure 7b As shown, the bendable section 3 is provided with 5 cavities, specifically:

[0122] (1) Two wire-drawing cavities 11 and 12, symmetrically distributed, to achieve two-way bending control;

[0123] (2) One perfusion cavity 10;

[0124] (3) One guide wire cavity 16;

[0125] (4) One functional cavity 21, in which a wire for controlling the loop is arranged. At this time, wires are arranged along the gap between the inner wall of the perfusion cavity 10 and the outer wall of the fluid tube 20, and wires are arranged along the gap between the inner wall of the guide wire cavity 16 and the outer wall of the guide wire tube 19.

[0126] Another difference is that two wire-drawing wires are fixed in the transition connection section 2, and then the two wire-drawing wires respectively extend along the wire-drawing cavities 11 and 12 in the bendable section 3 to the handle 5, while the wire for controlling the loop extends along the functional cavity 21 in the bendable section 3 to the handle 5. Thus, two sets of control systems are integrated on the handle 5. One set is for rotating the control wire-drawing wire to achieve bending control, and the other set is for pushing and controlling the wire for controlling the loop to achieve control of the loop. In addition, the magnetic positioning sensor can also be arranged in the transition connection section 2.

[0127] As can be understood by those skilled in the art, the head end electrode section 1 needs to be shaped into a ring shape. Therefore, a shaping wire is arranged inside the head end electrode section 1. The material of the shaping wire is usually a shape memory material such as nitinol alloy. The shaping wire is pre-shaped into a ring shape, which can constrain the head end electrode section 1 into a ring shape. In addition, the wire for controlling the loop can adjust the size of the ring shape, so that the diameter of the ring shape can be changed to be suitable for blood vessels of different sizes at the distal end.

[0128] Finally, it should be noted that the design concepts of other shapes of the head end electrode section 1 are similar to the above-mentioned linear and ring shapes, and will not be elaborated here.

[0129] In summary, in the ablation catheter of the present application, it includes a catheter body. The catheter body includes a distal electrode section, a transition connection section, a bendable section, a main body section, and a handle that are sequentially connected from far to near. And the catheter body is provided with a wire passage that penetrates axially; and a wire pulling system. The wire pulling system includes at least two wires. The proximal end of each wire is connected to the handle, and the distal end of each wire is connected to the distal electrode section or the transition connection section. At least two wires can be driven to control the bendable section to bend in different directions. Since the ablation catheter itself reserves a wire passage, during the operation, it is convenient to combine the wire to achieve the placement of the catheter in the tissue structure, thereby reducing the operation difficulty of the operation, improving the operation efficiency, reducing the amount of radiation injection, increasing the safety of the operation. In addition, after the catheter is in place, the bendable section can be bent by means of the handle to improve the abutting performance of the catheter, reduce the damage to the blood vessel, and improve the ablation effect.

[0130] It should be noted that the above-mentioned several embodiments can be combined with each other. The above description is only a description of the preferred embodiments of the present application, and does not limit the scope of the present application in any way. Any changes and modifications made by those of ordinary skill in the art of the present application according to the above disclosure are within the protection scope of the present application.

Claims

1. An ablation catheter, characterized in that: include: A catheter body, the catheter body comprising a head end electrode segment, a transition connection segment, a bendable segment, a main body segment and a handle connected in sequence from distal to proximal, and the catheter body is provided with an axially penetrating guidewire passage; and, A pull wire system, the pull wire system includes at least two pull wires, the proximal end of each pull wire is connected to the handle, the distal end of each pull wire is connected to the head end electrode segment or the transition connection segment, and at least two of the pull wires can be driven to control the bendable segment to bend in different directions.

2. The ablation catheter according to claim 1, characterized in that: The distal end of the guidewire passage is flush with the distal end of the head end electrode segment; the head end electrode segment further includes an infusion hole, and the catheter body is further provided with an axially extending fluid passage, and the distal end of the fluid passage is connected to the infusion hole; The guidewire passage is isolated from the fluid passage, or the guidewire passage is arranged in the fluid passage and forms a gap with the fluid passage, and the proximal end of the gap is sealed.

3. The ablation catheter according to claim 2, characterized in that: The guide wire passage is coaxially arranged in the fluid passage and forms an annular gap with the fluid passage. The proximal end of the annular gap is sealed and blocked, and the distal end of the annular gap is sealed and blocked or opened.

4. The ablation catheter according to claim 2, characterized in that: The transition connecting section is a single-lumen tube, and the bendable section is a multi-lumen tube; The catheter body also includes a fluid tube and a guide wire tube, and the fluid tube and the guide wire tube are arranged in the handle, the main body section and the transition connection section; When the guidewire passage and the fluid passage are isolated from each other, a guidewire cavity and a perfusion cavity are provided in both the head end electrode segment and the bendable segment, the guidewire cavity and the guidewire tube are provided correspondingly and communicated, the perfusion cavity and the fluid tube are provided correspondingly and communicated, and the guidewire cavity and the inner cavity of the guidewire tube constitute the guidewire passage, and the perfusion cavity and the inner cavity of the fluid tube constitute the fluid passage; When the guidewire passage is arranged in the fluid passage, perfusion cavities are arranged in the head end electrode segment and the flexible segment, the perfusion cavities are arranged corresponding to and connected with the fluid tube, the perfusion cavities and the gap between the fluid tube and the guidewire tube constitute the fluid passage, and the inner cavity of the guidewire tube constitutes the guidewire passage.

5. The ablation catheter according to claim 4, characterized in that: 4 to 6 cavities are arranged in the head end electrode segment, and 4 to 5 cavities are arranged in the bendable segment.

6. The ablation catheter according to claim 4, characterized in that: Also includes: wire; The head end electrode segment is provided with a wire cavity, and the wire cavity accommodates the wire; when the wire extends from the head end electrode segment via the transition connection segment to the bendable segment, it is distributed along the gap between the inner wall of the corresponding cavity in the bendable segment and the outer wall of the fluid tube, and / or, distributed along the gap between the inner wall of the corresponding cavity in the bendable segment and the outer wall of the guide wire tube.

7. The ablation catheter according to claim 4, characterized in that: When the guide wire passage is arranged in the fluid passage, the catheter body also includes a guide wire hose, one end of which passes through the proximal side wall of the fluid tube and the gap and is connected to the inner cavity of the guide wire tube. Alternatively, the catheter body also includes an irrigation hose, one end of which is arranged at the proximal end face of the fluid tube and is connected to the gap.

8. The ablation catheter according to claim 1 or 2, characterized in that: There are two pull wires, and the distal end of each pull wire is fixed in the proximal pull wire cavity of the head end electrode segment, or the distal end of each pull wire is fixed at the distal end of the transition connection segment.

9. The ablation catheter according to claim 1 or 2, characterized in that: The head end electrode segment is in a straight line, ring, claw or flower shape.

10. The ablation catheter according to claim 1 or 2, characterized in that: Also includes: At least one of a temperature sensor and a magnetic positioning sensor; the temperature sensor is mounted on the head end electrode segment; the magnetic positioning sensor is mounted on the head end electrode segment or the transition connection segment.

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