Hot melt adhesive patch production line

Abstract

The hot melt adhesive patch production line comprises a coating machine, a film cutting machine, a patch weighing machine, a stacking machine and a four-edge sealing packaging machine, the coating machine is arranged on the upstream of the film cutting machine, and the film cutting machine, the patch weighing machine, the stacking machine and the four-edge sealing packaging machine are sequentially connected. According to the hot melt adhesive patch production line disclosed by the utility model, stirred liquid medicine is coated by the coating machine, is transversely cut and longitudinally cut into slices by the film cutting machine, and then is subjected to weighing detection, stacking and four-edge sealing packaging to form a packaging product with one or more medicine patches in one bag. According to the utility model, a whole-line solution can be provided for clients, whole-line linkage control is realized, the product manufacturing process is optimized and simplified, the equipment development cost is saved, and the production efficiency is improved.

Description

Technical Field

[0001] The utility model relates to the field of food and drug packaging machinery, in particular to a hot melt adhesive patch production line. Background Art

[0002] At present, the intake methods of injection and oral drugs may not meet the needs of some patients. Therefore, with the advancement of research, a third drug intake method has gradually emerged, that is, transdermal patch administration. This method is to evenly coat the drug on a coil, and then package it through corresponding technological processes. When a patient needs to use it, they only need to apply it on the skin surface. The drug is in close contact with the skin and is absorbed by the skin and then ingested by the patient to treat various diseases. The new transdermal preparations include types such as orally dissolving films, transdermal patches, hydrogel patches, and hot melt patches. Compared with traditional rubber patches, they have advantages such as better drug release properties, less side effects, and convenient use.

[0003] To meet the market demand for hot melt adhesive patch drugs, in the process of producing hot melt patches, the coating machine, film cutting machine, and four-side sealing packaging machine are provided by different equipment manufacturers respectively. It is very difficult for the equipment of different equipment manufacturers to be compatible with each other, let alone achieve whole-line linkage control. This makes it very difficult to meet the production requirements of mass-produced patch products for pharmaceutical companies, not only increasing costs and affecting production efficiency, but also unable to meet market demand and create more value for pharmaceutical companies. Content of the Utility Model

[0004] The technical problem to be solved by the utility model is to overcome the deficiencies of the prior art and provide a hot melt adhesive patch production line that can provide a whole-line solution for customers, streamline the product manufacturing process, save equipment development costs, and improve production efficiency.

[0005] To solve the above technical problem, the utility model adopts the following technical solutions:

[0006] A hot melt adhesive patch production line includes a coating machine, a film cutting machine, a patch weighing machine, a stacking machine, and a four-side sealing packaging machine. The coating machine is arranged upstream of the film cutting machine, and the film cutting machine, patch weighing machine, stacking machine, and four-side sealing packaging machine are connected in sequence.

[0007] As a further improvement of the above technical solution: the coating machine includes a coating die head, a coating thickness detection device, and a thickness non-conforming spraying marking device arranged in sequence; the film cutting machine includes a visual detection device for marking non-conforming film thickness.

[0008] As a further improvement of the above technical solution: at least one set of laminating roller assemblies is arranged between the coating thickness detection device and the thickness non-conforming spraying marking device. The laminating roller assembly includes two laminating rollers arranged oppositely up and down and capable of rotating independently.

[0009] As a further improvement of the above technical solution: downstream of the thickness non - compliant spraying marking device, there are successively arranged a first cooling roller for cooling the front side of the patch and a second cooling roller for cooling the back side of the patch.

[0010] As a further improvement of the above technical solution: the hot melt adhesive patch production line further includes a curing room, and the curing room is arranged between the coater and the film cutting machine.

[0011] As a further improvement of the above technical solution: the film cutting machine includes a unwind roller, a tension control device, a deviation rectifying device, a defect vision detection device, a first cutting device and a second cutting device arranged in sequence, and the cutting directions of the first cutting device and the second cutting device are opposite.

[0012] As a further improvement of the above technical solution: the coater includes two winding rollers, and the unwind roller is equipped with a spare unwind roller.

[0013] As a further improvement of the above technical solution: the stacking machine includes a stacking robot, a feeding conveyor track docked with the discharge port of the film cutting machine, and a discharging conveyor track docked with the feeding port of the four - side sealing packaging machine; the patch weighing machine is arranged below the feeding conveyor track.

[0014] As a further improvement of the above technical solution: the four - side sealing packaging machine includes a pre - bonding film device, a heat - sealing device, a material clamping detection device, a third cutting device and a fourth cutting device arranged in sequence, and the cutting directions of the third cutting device and the fourth cutting device are opposite.

[0015] As a further improvement of the above technical solution: there is a concave - convex buckle pressing device between the heat - sealing device and the material clamping detection device;

[0016] And / or, there is a tear - notch punching device between the material clamping detection device and the third cutting device.

[0017] Compared with the prior art, the advantages of the present utility model are as follows: the hot melt adhesive patch production line disclosed by the present utility model mainly includes equipment such as a coater for coating hot melt adhesive, a film cutting machine, a patch weighing machine, a stacking machine and a four - side sealing packaging machine. After the stirred liquid medicine is coated by the coater and then transversely and longitudinally cut into pieces by the film cutting machine, it is then subjected to weighing detection, stacking, and four - side sealing packaging to form a packaged product with one or more patches in one package. The present utility model can provide a whole - line solution for customers, realize whole - line linkage control, optimize and streamline the product manufacturing process, save the equipment development cost, and improve the production efficiency.

[0018] Other features and advantages of the present utility model will be described in detail in the subsequent specific implementation part. Description of the Drawings

[0019] Figure 1 It is a top - view structural schematic diagram of the hot - melt adhesive patch production line of the present utility model.

[0020] Figure 2 It is a front - view structural schematic diagram of the hot - melt adhesive patch production line of the present utility model.

[0021] Figure 3 It is an enlarged view of the coater and the curing room in the present utility model.

[0022] Figure 4 It is an enlarged view of the die - cutting machine in the present utility model.

[0023] Figure 5 It is an enlarged view of the stacker in the present utility model.

[0024] Figure 6 It is an enlarged view of the four - side sealing packaging machine in the present utility model.

[0025] Figure 7 It is a structural schematic diagram of the coating process of the present utility model.

[0026] Figure 8 It is a structural schematic diagram of the film - covering and laminating processes of the present utility model.

[0027] Figure 9 It is a structural schematic diagram of the die - cutting process of the present utility model.

[0028] Figure 10 It is a structural schematic diagram of the stacking process of the present utility model.

[0029] Figure 11 It is a structural schematic diagram of the process of feeding the packaging bag film material of the present utility model.

[0030] Figure 12 It is a structural schematic diagram of the pre - laminating film process of the present utility model.

[0031] Figure 13 It is a structural schematic diagram of the heat - sealing process of the present utility model.

[0032] Figure 14 It is a structural schematic diagram of the die - cutting process of the packaging bag of the present utility model.

[0033] Figure 15 It is a structural schematic diagram of the product obtained by the present utility model.

[0034] Each label in the figure represents:

[0035] 1. Coating machine; 11. Coating die head; 12. Coating thickness detection device; 13. Spraying marking device for unqualified thickness; 14. Laminating roller; 15. First cooling roller; 16. Second cooling roller; 17. Rewinding roller; 2. Film cutting machine; 21. Visual detection device for marking unqualified sheet thickness; 22. Unwinding roller; 23. Tension control device; 24. Deviation rectification device; 25. Defect visual detection device; 26. First cutting device; 27. Second cutting device; 28. Spare unwinding roller; 3. Chip weighing machine; 4. Stacking machine; 41. Stacking robot; 42. Infeed conveying track; 43. Outfeed conveying track; 5. Four-side sealing packaging machine; 51. Pre-laminating film device; 52. Heat sealing device; 53. Clamping detection device; 54. Third cutting device; 55. Fourth cutting device; 56. Concave-convex buckle pressing device; 57. Easy-tear opening punching device; 58. Corner machine; 6. Aging room. Detailed implementation mode

[0036] In the description of the present invention, it should be understood that the orientation or positional relationship indicated by the terms "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation to the present invention.

[0037] In addition, the terms "first" and "second" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include one or more of such features. In the description of the present invention, "a plurality" means two or more unless otherwise specifically defined.

[0038] In the present invention, unless otherwise clearly specified and limited, the terms "assembly", "connected", "connected", "fixed", etc. should be understood in a broad sense. For example, it may be a fixed connection, a detachable connection, or an integral body; it may be a mechanical connection or an electrical connection; it may be directly connected or indirectly connected through an intermediate medium, and it may be the internal communication of two elements or the interaction relationship between two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0039] The present invention will be further described in detail below with reference to the accompanying drawings of the specification and specific embodiments.

[0040] Figures 1 to 15An embodiment of the hot melt adhesive patch production line of the present utility model is shown. The hot melt adhesive patch production line of this embodiment includes a coating machine 1, a die cutting machine 2, a patch weighing machine 3, a stacking machine 4, and a four-side sealing packaging machine 5. The coating machine 1 is arranged upstream of the die cutting machine 2, and the die cutting machine 2, the patch weighing machine 3, the stacking machine 4, and the four-side sealing packaging machine 5 are connected in sequence (the coating machine 1 is an independent device, and it is not limited that it must be connected to the die cutting machine 2).

[0041] The hot melt adhesive patch production line of this embodiment mainly includes devices such as a coating machine 1 for coating hot melt adhesive, a die cutting machine 2, a patch weighing machine 3, a stacking machine 4, and a four-side sealing packaging machine 5. After the stirred liquid medicine is coated by the coating machine 1 and then transversely and longitudinally cut into pieces by the die cutting machine 2, it is then subjected to weighing detection, stacking, and four-side sealing packaging to form a packaged product with one or more patches in one package. The present utility model can provide a whole-line solution for customers, realize whole-line linkage control, optimize and streamline the product manufacturing process, save equipment development costs, and improve production efficiency. For details, see Figure 3 , for the liquid medicine that still needs to undergo precipitation and gelatinization reactions after partial coating, a ripening room 6 can also be set up. The film roll after coating and winding is placed in the ripening room 6, and then transferred to the die cutting machine 2 after reaching the set time. Preferably, the ripening room 6 can be arranged between the coating machine 1 and the die cutting machine 2 to reduce the transfer distance of the film roll (similar to the coating machine 1, the ripening room 6 is also an independent device, and it is not limited that it must be connected to the die cutting machine 2).

[0042] Furthermore, in this embodiment, the coating machine 1 includes a coating die head 11, a coating thickness detection device 12, and a thickness non-conforming spraying marking device 13 arranged in sequence. The stirred liquid medicine is coated on the base film through the coating die head 11, the coating thickness detection device 12 detects the thickness of the coating, and the thickness non-conforming parts are sprayed and marked by the thickness non-conforming spraying marking device 13, such as non-conforming text marks or pattern marks, etc. Subsequently, the corresponding patches are removed after being cut into pieces by the die cutting machine 2, which is beneficial to improving the uniformity of drug quality and the accuracy of drug administration. Correspondingly, in this embodiment, the die cutting machine 2 includes a visual detection device 21 for detecting marks of non-conforming sheet thickness. The die cutting machine 2 detects whether there are non-conforming marks through the visual detection device 21 for detecting marks of non-conforming sheet thickness, and the patches with non-conforming marks are removed, for example, the non-conforming patches are taken away from the conveyor belt by a liftable negative pressure suction cup.

[0043] As a preferred embodiment, there are two sets of laminating roller assemblies between the coating thickness detection device 12 and the thickness unqualified spraying marking device 13. The laminating roller assembly includes two laminating rollers 14 arranged opposite to each other up and down and capable of independent rotation. The laminating roller assembly is used to laminate the base film (mostly release film) and the coated film (mostly non-woven fabric). The two upper and lower laminating rollers 14 can rotate independently, which is beneficial to ensure smooth lamination of the non-woven fabric without wrinkles. Of course, in other embodiments, one or three sets of laminating roller assemblies can also be provided.

[0044] Further, in this embodiment, downstream of the thickness unqualified spraying marking device 13, there are successively arranged a first cooling roller 15 for cooling the front side of the patch and a second cooling roller 16 for cooling the back side of the patch. That is, the front side of the laminated strip after lamination contacts the first cooling roller 15, and the back side contacts the second cooling roller 16. After lamination, the first cooling roller 15 and the second cooling roller 16 are used to cool the front and back sides of the laminated patch, so that the patch is cooled to room temperature. The cooling effect is uniform, and the structure is simple and effective.

[0045] Specifically, the stirred liquid medicine is transported to the release film at the coating die head 11 of the coater 1. The release film passes through devices such as unwinding, tension control, tension detection, and deviation correction and reaches the coating die head 11. After coating, it passes through the coating thickness detection device 12 and reaches the primary lamination station, where it is laminated with the non-woven fabric that has passed through devices such as unwinding, static elimination, deviation correction, and tension detection; after secondary lamination, the front and back sides of the liquid medicine are cooled, and finally, it passes through devices such as a tension swing arm, tension detection, deviation correction, and traction mechanism and reaches the winding place for winding.

[0046] Further, in this embodiment, the film cutting machine 2 includes a unwind roller 22, a tension control device 23 (such as a tension control swing arm, etc.), a deviation correction device 24, a defect vision detection device 25, a first cutting device 26, and a second cutting device 27 arranged in sequence. The cutting directions of the first cutting device 26 and the second cutting device 27 are opposite. The film roll after coating on the coater 1 is loaded on the unwind roller 22 of the film cutting machine 2. After transverse and longitudinal cutting by the tension control device 23, the deviation correction device 24, the defect vision detection device 25, the first cutting device 26, and the second cutting device 27, multiple columns of medicine patches of a certain size specification are formed, and then they are transported to the next station by a conveyor mesh belt. During the process, the waste edges generated at the edges of the film roll reach the waste collection roller through the tension swing arm and the traction system for centralized waste collection. The high-precision film cutting process combined with functions such as deviation correction and thickness detection can ensure the product size and quality, improve the raw material utilization rate, and reduce the waste caused by excess waste edges. Preferably, the defect vision detection device 25 and the film thickness unqualified marking vision detection device 21 can be integrated into one, that is, the vision detection device simultaneously detects the film thickness unqualified marking and the patch defect, which is beneficial to simplifying the structure, making the equipment size more compact, and also beneficial to reducing costs.

[0047] Further, the coater 1 includes two winding rollers 17. During use, the two winding rollers 17 wind alternately. The unwinding roller 22 of the film cutting machine 2 is provided with a spare unwinding roller 28. The film rolls on the two winding rollers 17 can be removed and loaded onto the unwinding roller 22 and the spare unwinding roller 28 respectively. The unwinding roller 22 unwinds first, and the spare unwinding roller 28 is ready at any time, which is beneficial to improving the production efficiency and reliability of the production line.

[0048] Further, in this embodiment, the stacking machine 4 includes a stacking robot 41, a feeding conveyor track 42 docked with the discharge port of the film cutting machine 2, and a discharge conveyor track 43 docked with the feeding port of the four-side sealing packaging machine 5. The feeding conveyor track 42 and the discharge conveyor track 43 are preferably conveyor belts. Of course, in other embodiments, they can also be in other forms. In this embodiment, the patch weighing machine 3 is arranged below the feeding conveyor track 42 for on-line weighing of each patch to realize weighing detection for each patch. Multiple rows of cut medicine patches are conveyed by the conveyor belt to the patch weighing machine 3 for on-line weighing detection, and then conveyed by the feeding conveyor belt to the stacking machine 4. The stacking machine 4 stacks one or more medicine patches together and converts them into 2 rows and places them on the 2-row discharge conveyor belts below the stacking machine 4, and is conveyed by the 2-row discharge conveyor belts to the four-side sealing packaging machine 5.

[0049] Preferably, the stacked medicine patches enter the four-side sealing packaging machine 5 from left to right, and the film roll (or the packaging bag film roll) for packaging the medicine patches enters the four-side sealing packaging machine 5 in the front-back direction, that is, the medicine patch feeding direction and the film roll feeding direction are perpendicular, which is beneficial to making full use of the plant area and shortening the length of the production line. For this reason, the four-side sealing packaging machine 5 needs to be provided with a corner machine 59 to first convert the packaging bag film roll by 90°, and then perform operations such as pre-closing the film and heat sealing. For details, please refer to Figure 11 .

[0050] Further, the four-side sealing packaging machine 5 includes a pre-closing film device 51, a heat sealing device 52, a clamping detection device 53, a third cutting device 54, and a fourth cutting device 55 arranged in sequence. The cutting directions of the third cutting device 54 and the fourth cutting device 55 are opposite (that is, vertical cutting and horizontal cutting are respectively completed to obtain products distributed in a rectangular array). An uneven buckle pressing device 56 (wherein, the uneven buckle is also called a plastic zipper) is arranged between the heat sealing device 52 and the clamping detection device 53; or an easy tear opening punching device 57 is arranged between the clamping detection device 53 and the third cutting device 54.

[0051] The medicated patches conveyed by the two-column feeding conveyor belt reach the four-side sealing packaging machine 5. After being pre-laminated by the pre-laminating film device 51 together with the concave-convex buttons and the upper and lower packaging films, the four-side sealing treatment is carried out by the heat-sealing device 52. After the four-side sealing is completed, the clamping and inspection device 53 is used to detect whether there is poor sealing during the heat-sealing of the heat-sealing device 52. The strip reaches the third cutting device 54 and the fourth cutting device 55 for cutting and producing the finished packaging. The above process can also be changed according to different situations to perform the heat-sealing treatment by the heat-sealing device 52, then detected by the clamping and inspection device 53, and the longitudinal cutting and transverse cutting processes are respectively completed by the traction mechanism, the easy-tear opening punching device 57, the third cutting device 54 and the fourth cutting device 55 to produce the finished packaging. Then the packaging bag will enter the waste removal station, and the waste removal station will accurately remove the unqualified products recorded by the front-end devices such as coating thickness detection, weighing detection, vision detection, and / or clamping detection. The qualified products are conveyed by the conveyor belt to other back-end devices for product boxing, packing, palletizing, etc.

[0052] Although the present utility model has been disclosed above with preferred embodiments, it is not intended to limit the present utility model. Any person skilled in the art can make many possible changes and modifications to the technical solution of the present utility model, or modify it into an equivalent embodiment with equivalent changes, without departing from the scope of the technical solution of the present utility model. Therefore, any simple modification, equivalent change and modification made to the above embodiments according to the technical essence of the present utility model without departing from the content of the technical solution of the present utility model shall fall within the scope of protection of the technical solution of the present utility model.

Claims

1. A hot melt adhesive patch production line, characterized in that: The invention comprises a coating machine (1), a film cutting machine (2), a patch weighing machine (3), a stacking machine (4) and a four-side sealing packaging machine (5), wherein the coating machine (1) is arranged upstream of the film cutting machine (2), and the film cutting machine (2), the patch weighing machine (3), the stacking machine (4) and the four-side sealing packaging machine (5) are connected in sequence.

2. The hot melt adhesive patch production line according to claim 1, characterized in that: The coating machine (1) comprises a coating die head (11), a coating thickness detection device (12) and a thickness unqualified spray marking device (13) which are arranged in sequence; the film cutting machine (2) comprises a film thickness unqualified marking visual detection device (21).

3. The hot melt adhesive patch production line according to claim 2, characterized in that: At least one set of laminating roller components is provided between the coating thickness detection device (12) and the unqualified thickness spray marking device (13), and the laminating roller component comprises two laminating rollers (14) which are arranged opposite to each other up and down and can rotate independently.

4. The hot melt adhesive patch production line according to claim 2, characterized in that: A first cooling roller (15) for cooling the front side of the patch and a second cooling roller (16) for cooling the back side of the patch are sequentially arranged downstream of the unqualified thickness spray marking device (13).

5. The hot melt adhesive patch production line according to claim 1, characterized in that: It also includes a aging room (6), which is arranged between the coating machine (1) and the film cutting machine (2).

6. The hot melt adhesive patch production line according to claim 1, characterized in that: The film cutting machine (2) comprises an unwinding roller (22), a tension control device (23), a deviation correction device (24), a defect visual detection device (25), a first cutting device (26) and a second cutting device (27) which are arranged in sequence, and the cutting directions of the first cutting device (26) and the second cutting device (27) are opposite.

7. The hot melt adhesive patch production line according to claim 6, characterized in that: The coating machine (1) comprises two winding rollers (17), and the unwinding roller (22) is provided with a spare unwinding roller (28).

8. The hot melt adhesive patch production line according to any one of claims 1 to 7, characterized in that: The stacking machine (4) comprises a stacking robot (41), a feed conveying track (42) connected to the discharge port of the film cutting machine (2), and a discharge conveying track (43) connected to the feed port of the four-side sealing packaging machine (5); the patch weighing machine (3) is arranged below the feed conveying track (42).

9. The hot melt adhesive patch production line according to any one of claims 1 to 6, characterized in that: The four-side sealing packaging machine (5) comprises a pre-filming device (51), a heat sealing device (52), a material clamping detection device (53), a third cutting device (54) and a fourth cutting device (55) which are arranged in sequence, and the cutting directions of the third cutting device (54) and the fourth cutting device (55) are opposite.

10. The hot melt adhesive patch production line according to claim 9, characterized in that: A concave-convex buckle pressing device (56) is provided between the heat sealing device (52) and the material clamping detection device (53); And / or, an easy-tear punching device (57) is provided between the material clamping detection device (53) and the third cutting device (54).

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