Intelligent liquid-based cell dyeing machine

Abstract

The utility model discloses an intelligent liquid-based cell dyeing machine. The intelligent liquid-based cell dyeing machine comprises a box body, the number of the clamping plates is two, the two clamping plates are arranged in the box body, and the two clamping plates are respectively used for loading a glass slide and a cover glass; and the number of the bidirectional electric rods is two, the two bidirectional electric rods are arranged on the top wall in the box body, the telescopic end of each bidirectional electric rod is fixedly connected with one clamping plate, and the bidirectional electric rods are used for driving the clamping plates to be opened and closed. By using the clamping plate, the bidirectional electric rod, the sample pump, the discharging nozzle, the conveying assembly, the control panel and the disinfecting and heating module, glass slides and cover glass which need to be used when samples are dyed can be automatically stacked, meanwhile, the samples can be automatically dropwise added, and the samples can be driven to automatically move to add different dyeing agents; and the used supporting plate can be automatically cleaned and dried, so that the accuracy of an observation result after cell staining is ensured.

Description

Technical Field

[0001] The utility model relates to the technical field of medical equipment, in particular to an intelligent liquid-based cell staining machine. Background Art

[0002] The staining machine is an analytical instrument used in the fields of biology, basic medicine, pharmacy, traditional Chinese medicine and Chinese herbal medicine. It is used in routine pathology and cytology experiments. It is mainly suitable for the staining of cells, body fluids and blood components before pathological analysis. In the past, the preparation of specimen slides was mainly completed manually, but with the rapid increase in population and the development of medical technology, the status of the medical and health industry in today's society has been further enhanced. The shortage of medical staff has become an increasingly obvious obstacle to the development of the medical industry. When the amount of sample inspection is huge, due to the complexity of the preparation of cytological specimen slides and the high requirements on the quality and ability of operators for manual staining, the manual preparation of specimen slides is inefficient and costly. At the same time, some staining reagents are highly corrosive and volatile. Working in the staining room for a long time will have a certain impact on the health of the operator.

[0003] At present, automation technology has been gradually introduced into the medical industry, and has spawned a series of medical automation products. Especially in the field of medical testing, testing equipment based on mechanical automation has achieved phased results in helping medical test personnel complete some repetitive and highly standardized tasks. Hospitals and testing institutions at all levels in my country have purchased a large number of advanced testing equipment. Whether it is the laboratory department of provincial and municipal hospitals or the laboratory department of township and town health centers, they are gradually realizing the upgrade from manual testing to semi-automated or even fully automated testing. The efficiency of medical testing has been greatly improved, and the labor intensity of relevant staff has been greatly reduced, gradually realizing the improvement of my country's testing level and testing capabilities.

[0004] In response to the above situation, we have launched a fully automatic intelligent cell staining machine. The staining machine is fully controlled by a computer and the staining program can be set independently according to the staining requirements. It can achieve more efficient automatic stacking of slides, adding samples, stacking of cover slips, adding different stains and drying. It is safer and more efficient when used. It can greatly reduce the waste rate of staining, and to a certain extent improve the staining quality stability and convenience of existing staining machines. Utility Model Content

[0005] The purpose of the utility model is to provide an intelligent liquid-based cell staining machine, which solves the problems that the slides and cover slips needed for sample staining cannot be automatically stacked, the samples cannot be dripped, and the samples cannot be automatically moved to add different stains, and the support plates after use cannot be automatically cleaned and dried, and the accuracy of the observation results after cell staining cannot be guaranteed.

[0006] The present utility model solves the above technical problems through the following technical solutions. The present utility model includes:

[0007] A box body;

[0008] Clamping plates. The number of the clamping plates is two, and both of the clamping plates are installed in the box body. The two clamping plates are respectively used for loading glass slides and cover glasses;

[0009] Two-way electric rods. The number of the two-way electric rods is two, and both of the two-way electric rods are installed on the inner top wall of the box body. The telescopic end of each two-way electric rod is fixedly connected to a clamping plate respectively. The two-way electric rod is used to drive the clamping plate to open and close;

[0010] A sample box. The sample box is installed in the box body. The sample box is used for loading samples. A sample pump is fixedly installed at the bottom of the sample box, and a discharge nozzle is fixedly installed on the water outlet of the sample pump;

[0011] A conveying component. The conveying component is installed in the box body. The conveying component is used for stacking and conveying samples. The conveying component includes a first motor and a push rod. The push rod is fixedly connected to the output shaft of the first motor, and a tray is fixedly installed at the telescopic end of the push rod;

[0012] A control panel. The control panel is fixedly installed outside the box body. The control panel is used to control the start and stop of each component in the staining machine.

[0013] Preferably, the conveying component includes a gear and a second motor. The output shaft of the second motor is fixedly connected to the gear. A telescopic rod is fixedly installed on the second motor, and the telescopic end of the telescopic rod is fixedly connected to the first motor.

[0014] Preferably, the box body is equipped with a disinfection and heating module. The disinfection and heating module is used to disinfect the tray and dry the samples.

[0015] Preferably, the disinfection and heating module includes a disinfection and heating box. A disinfection pump is fixedly installed on the side wall of the disinfection and heating box. A disinfection water tank is fixedly installed on the disinfection pump. An air outlet plate, a fan and a heating wire are fixedly installed inside the disinfection and heating box.

[0016] Preferably, a staining agent box is fixedly installed inside the box body.

[0017] Preferably, a chute is opened on the inner top wall of the box body, and both of the two-way electric rods are slidably connected to the chute.

[0018] Preferably, a sliding rod is fixedly installed on the side wall of the sample box, and the fixed end of the sliding rod is fixedly installed on the inner side wall of the box body.

[0019] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0020] 1. By using the clamping plate, bidirectional electric rod, sample pump, discharge nozzle, conveying component and control panel, the present utility model can achieve the effects of automatically stacking the glass slides and cover glasses required for sample staining and automatically dropping the samples, can drive the samples to move automatically to add the required staining agents, and through the control of each component by the control panel, can achieve the effect of full-automatic staining process, making the staining process more flexible and efficient, improving the accuracy, and greatly reducing the waste film rate;

[0021] 2. By the combined use of the conveying component and the disinfection and heating module, the present utility model can achieve the effects of automatically cleaning and drying the used pallet, can prevent the mixing of different cells, prevent cross-infection, and ensure the accuracy of the observation results after cell staining. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 is the right view structural schematic diagram of the present utility model;

[0023] Figure 2 is the bottom view structural schematic diagram of the present utility model;

[0024] Figure 3 is the bottom view structural schematic diagram of the box body and the chute of the present utility model;

[0025] Figure 4 is the rear view structural schematic diagram of the sample box and the slide bar of the present utility model;

[0026] Figure 5 is the split structural schematic diagram of the conveying component of the present utility model;

[0027] Figure 6 is the top view structural schematic diagram of the disinfection and heating module of the present utility model.

[0028] The numbers in the figures represent:

[0029] 1 - box body; 2 - clamping plate; 3 - bidirectional electric rod; 4 - sample box; 401 - sample pump; 402 - discharge nozzle; 5 - conveying component; 501 - motor 1; 502 - push rod; 503 - pallet; 504 - gear; 505 - motor 2; 506 - telescopic rod; 6 - control panel; 7 - disinfection and heating module; 701 - disinfection and heating box; 702 - disinfection pump; 703 - disinfection water tank; 704 - air outlet plate; 705 - fan; 706 - heating wire; 8 - staining agent box; 9 - chute; 10 - slide bar. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0030] The following further elaborates on the above and additional technical features and advantages of the present utility model in conjunction with the accompanying drawings.

[0031] Embodiment 1

[0032] This embodiment provides a technical solution: an intelligent liquid-based cell staining machine, as Figures 1-6 shown, comprising: a box body 1, clamping plates 2, bidirectional electric rods 3, a sample box 4, a conveying assembly 5, and a control panel 6;

[0033] As Figures 1-5 shown, the number of clamping plates 2 is two, and both clamping plates 2 are installed in the box body 1. The two clamping plates 2 are respectively used for loading glass slides and cover glasses; the glass slides and cover glasses can be stacked and placed in the two clamping plates 2 respectively, which is convenient for stacking glass slides and cover glasses on the support plate 503. The number of bidirectional electric rods 3 is two, and both bidirectional electric rods 3 are installed on the inner top wall of the box body 1. The telescopic end of each bidirectional electric rod 3 is fixedly connected to a clamping plate 2, and the bidirectional electric rod 3 is used to drive the clamping plate 2 to open and close; the sample box 4 is installed inside the box body 1, and the sample box 4 is used for loading samples. A sample pump 401 is fixedly installed at the bottom of the sample box 4, and a discharge nozzle 402 is fixedly installed at the water outlet of the sample pump 401; the start of the sample pump 401 can be controlled through the control panel 6. The conveying assembly 5 is installed inside the box body 1, and the conveying assembly 5 is used to facilitate the automatic stacking and conveying of samples. The conveying assembly 5 includes a motor 501 and a push rod 502. The push rod 502 is fixedly connected to the output shaft of the motor 501. A support plate 503 is fixedly installed at the telescopic end of the push rod 502. The motor 501 can drive the push rod 502 to rotate, and the push rod 502 drives the support plate 503 to rotate, enabling the support plate 503 to face different components; the control panel 6 is fixedly installed outside the box body 1, and the control panel 6 is used to control the start and stop of each component in the staining machine. The conveying assembly 5 includes a gear 504 and a motor 505. The output shaft of the motor 505 is fixedly connected to the gear 504. The motor 505 can drive the gear 504 to rotate, and the gear 504 can drive the motor 505 to move in the reverse direction. A telescopic rod 506 is fixedly installed on the motor 505, and the telescopic end of the telescopic rod 506 is fixedly connected to the motor 501. The telescopic rod 506 can adjust the height of the motor 501. A staining agent box 8 is fixedly installed inside the box body 1, and different staining agents can be loaded in the staining agent box 8.

[0034] The control panel 6 is used to control the start of the first motor 501 to drive the push rod 502 to rotate. The push rod 502 drives the support plate 503 to rotate, so that the support plate 503 rotates close to the side of the sample box 4 to the position below the clamping plate 2 adjacent to the sample box 4. The distance between the support plate 503 and the bottom of the clamping plate 2 is the thickness of a glass slide. The control panel 6 is used to control the start of the bidirectional electric rod 3. The bidirectional electric rod 3 drives the clamping plate 2 to expand. The bottommost glass slide falls from the clamping plate 2 to the first position in the first row on the support plate 503. The control panel 6 controls the contraction of the bidirectional electric rod 3. The bidirectional electric rod 3 drives the clamping plate 2 to close, and the clamping plate 2 clamps the remaining glass slides. By starting the telescopic rod 506 to extend, the first motor 501 is driven to descend. The first motor 501 drives the push rod 502 to descend, and the push rod 502 drives the support plate 503 to descend. By starting the push rod 502 to drive the support plate 503 to move away from the first motor 501, the push rod 502 stops when a glass slide on the support plate 503 moves out from below the clamping plate 2. By starting the telescopic rod 506 to contract, the first motor 501 is driven to rise. The first motor 501 drives the push rod 502 to rise, and the push rod 502 drives the support plate 503 to rise. The distance between the support plate 503 and the bottom of the clamping plate 2 is the thickness of a glass slide. Repeating the above step of starting the bidirectional electric rod 3, a glass slide can be placed at the first position in the second row on the support plate 503. Six rows of glass slides can be placed on the support plate 503. Repeating the above steps, a glass slide can be placed at the first position on the support plate 503.

[0035] Starting the step of extending the telescopic rod 506 drives the support plate 503 to descend. Then, by starting the second motor 505 to drive the gear 504 to rotate, the second motor 505 is limited by the box body 1, the gear 504 meshes with the box body 1. While the gear 504 rotates, it drives the second motor 505 to move. The second motor 505 drives the telescopic rod 506 to move, the telescopic rod 506 drives the first motor 501 to move, the first motor 501 drives the push rod 502 to move, and the push rod 502 drives the support plate 503 to move towards the sample box 4. When the bottommost glass slide in the first position of the sixth row on the support plate 503 moves out from below the clamping plate 2, the second motor 505 stops. Starting the step of contracting the telescopic rod 506 drives the support plate 503 to rise. By starting the bidirectional electric rod 3, a glass slide can be placed at the second position in the sixth row on the support plate 503. According to the steps of extending and contracting the telescopic rod 506, and then driving the support plate 503 to move by contracting the push rod 502, the support plate 503 drives the second glass slide in the sixth row to move out from below the clamping plate 2. Repeating the above steps of starting the bidirectional electric rod 3, the push rod 502, the second motor 505 and the telescopic rod 506, thirty glass slides in six rows and five columns can be placed on the support plate 503.

[0036] According to the starting steps of the second motor 505, it can drive the pallet 503 to move below the discharge nozzle 402. The pallet 503 drives the glass slide to move below the discharge nozzle 402. According to the starting steps of the cooperation among the above-mentioned bidirectional electric rod 3, the first motor 501, the push rod 502, the second motor 505 and the telescopic rod 506, then by starting the sample pump 401, the sample in the sample box 4 can be driven into the discharge nozzle 402, and the sample in the discharge nozzle 402 can be dropped onto each glass slide. Again, according to the starting steps of the cooperation among the above-mentioned bidirectional electric rod 3, the first motor 501, the push rod 502, the second motor 505 and the telescopic rod 506, the glass slide with the sample can be conveyed below the clamping plate 2 with the cover glass, and the cover glass can be covered on each glass slide with the sample on the pallet 503. Again, according to the starting steps of the cooperation among the above-mentioned bidirectional electric rod 3, the first motor 501, the push rod 502, the second motor 505 and the telescopic rod 506, it can drive the glass slide with the sample and the cover glass to move below the staining agent box 8 with the required staining agent. By controlling the staining agent box 8 to start through the control panel 6, the appropriate staining agent can be dropped into each sample, and the sample can be stained. According to the starting steps of the cooperation among the above-mentioned bidirectional electric rod 3, the first motor 501, the push rod 502, the second motor 505 and the telescopic rod 506, the sample on the pallet 503 can be conveyed into the disinfection and heating module 7, and the disinfection and heating module 7 can dry the sample and the staining agent on the glass slide to increase the color of the cells.

[0037] Embodiment 2

[0038] As Figure 6 shown, the box body 1 is provided with a disinfection and heating module 7. The disinfection and heating module 7 is used for disinfecting the pallet 503 and drying the sample. The disinfection and heating module 7 includes a disinfection and heating box 701. A disinfection pump 702 is fixedly installed on the side wall of the disinfection and heating box 701. A disinfection water tank 703 is fixedly installed on the disinfection pump 702. An air outlet plate 704, a fan 705 and a heating wire 706 are fixedly installed inside the disinfection and heating box 701.

[0039] After the sample is stained, the sample is removed. According to the above steps of the cooperation start among the bidirectional electric rod 3, the first motor 501, the push rod 502, the second motor 505 and the telescopic rod 506, the used pallet 503 can be moved into the disinfection and heating box 701. By controlling the disinfection pump 702 to start through the control panel 6, the disinfection pump 702 drives the disinfection water in the disinfection water tank 703 into the disinfection and heating box 701. The inner side wall of the disinfection and heating box 701 is provided with water spraying holes, and the disinfection water is sprayed out from the water spraying ports onto the surface of the pallet 503. The disinfection water can wash the surface of the pallet 503, prevent the sample from remaining on the pallet 503, and prevent the observation result from being inaccurate. Then, by starting the heating wire 706 to heat the top of the disinfection and heating box 701, and at the same time starting the blower 705, the blower 705 drives the hot air to blow from the air outlet plate 704 onto the surface of the pallet 503 and the inner bottom surface of the disinfection and heating box 701. The hot air can dry the disinfection water on the surface of the pallet 503 and the inner bottom surface of the disinfection and heating box 701. At the same time, the disinfection and heating module 7 can dry the sample to which the staining agent is added. The control panel 6 can not only control the bidirectional electric rod 3, the sample pump 401, the first motor 501, the push rod 502, the second motor 505, the telescopic rod 506, the disinfection pump 702, the blower 705, the heating wire 706 and the staining agent box 8, but also control each electrically controllable component in the staining machine.

[0040] As Figures 2-4 shown, a chute 9 is provided on the inner top wall of the box body 1. Both bidirectional electric rods 3 are slidably connected to the chute 9. By pulling the clamping plate 2 to move the bidirectional electric rod 3, the bidirectional electric rod 3 moves in the chute 9, which can make the clamping plate 2 close to the staff, facilitating the addition of glass slides and coverslips into the clamping plate 2. A sliding rod 10 is fixedly installed on the side wall of the sample box 4. The fixed end of the sliding rod 10 is fixedly installed on the inner side wall of the box body 1. By pulling the sample box 4, the sample box 4 drives the sliding rod 10 to extend, which can pull the sample box 4 out of the box body 1, facilitating the addition of samples into the sample box 4.

[0041] The above is only the preferred embodiment of the present utility model, which is illustrative rather than restrictive to the present utility model. Those skilled in the art understand that many changes, modifications, and even equivalents can be made within the spirit and scope defined by the claims of the present utility model, but all will fall within the protection scope of the present utility model.

Claims

1. An intelligent liquid-based cell staining machine, characterized in that: include: Box body (1); A clamping plate (2), wherein two clamping plates (2) are installed, and both clamping plates (2) are installed in the box body (1), and the two clamping plates (2) are used to load a slide glass and a cover glass respectively; Two bidirectional electric rods (3) are installed, and the two bidirectional electric rods (3) are installed on the inner top wall of the box body (1). The telescopic end of each bidirectional electric rod (3) is fixedly connected to one of the clamping plates (2), and the bidirectional electric rod (3) is used to drive the clamping plates (2) to open and close; A sample box (4), the sample box (4) is installed inside the box body (1), the sample box (4) is used to load the sample, a sample pump (401) is fixedly installed at the bottom of the sample box (4), and a discharge nozzle (402) is fixedly installed on the water outlet of the sample pump (401); A conveying assembly (5), the conveying assembly (5) is installed inside the box (1), the conveying assembly (5) is used to facilitate automatic stacking and transportation of samples, the conveying assembly (5) comprises a motor (501) and a push rod (502), the push rod (502) is fixedly connected to the output shaft of the motor (501), and a support plate (503) is fixedly installed at the telescopic end of the push rod (502); A control panel (6), wherein the control panel (6) is fixedly mounted on the outside of the box (1), and the control panel (6) is used to control the start and stop of various components in the dyeing machine.

2. An intelligent liquid-based cell staining machine as claimed in claim 1, characterized in that: The conveying assembly (5) comprises a gear (504) and a second motor (505), wherein the output shaft of the second motor (505) is fixedly connected to the gear (504), a telescopic rod (506) is fixedly mounted on the second motor (505), and the telescopic end of the telescopic rod (506) is fixedly connected to the first motor (501).

3. An intelligent liquid-based cell staining machine as claimed in claim 1, characterized in that: The box body (1) is equipped with a disinfection and heating module (7), and the disinfection and heating module (7) is used to disinfect the support plate (503) and dry the sample.

4. An intelligent liquid-based cell staining machine as claimed in claim 3, characterized in that: The disinfection and heating module (7) comprises a disinfection and heating box (701), a disinfection pump (702) is fixedly mounted on the side wall of the disinfection and heating box (701), a disinfection water tank (703) is fixedly mounted on the disinfection pump (702), and an air outlet plate (704), a fan (705) and a heating wire (706) are fixedly mounted inside the disinfection and heating box (701).

5. The intelligent liquid-based cell staining machine according to claim 1, characterized in that: A dye box (8) is fixedly mounted in the box body (1).

6. An intelligent liquid-based cell staining machine as claimed in claim 5, characterized in that: The inner top wall of the box body (1) is provided with a slide groove (9), and the two bidirectional electric rods (3) are both slidably connected to the slide groove (9).

7. The intelligent liquid-based cell staining machine according to claim 1, characterized in that: A sliding rod (10) is fixedly mounted on the side wall of the sample box (4), and a fixed end of the sliding rod (10) is fixedly mounted on the inner side wall of the box body (1).

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