Two-channel liquid automatic sample injector

Abstract

The utility model relates to the technical field of chromatographic analysis equipment, and discloses a double-channel liquid automatic sample injector which comprises a sample injector body, and an injector, a Y-shaped three-way valve, a first high-pressure valve, a second high-pressure valve, a sampling needle and a sample tray are arranged in the sample injector body. The injector, the Y-shaped three-way valve, the first high-pressure valve, the second high-pressure valve and the sampling needle are sequentially communicated through a connecting pipeline, and the sample tray is positioned below the sampling needle. The device disclosed by the utility model can be used for directly performing sample injection on two sets of chromatograms without repeatedly replacing pipelines and reconnecting, so that potential hidden dangers caused in the replacement process, such as liquid leakage, equipment damage and the like, are avoided. The workload of replacing equipment by a user can be directly reduced, and the working time is obviously reduced.

Description

Technical Field

[0001] The utility model relates to the technical field of chromatographic analysis equipment, in particular to a dual-channel liquid automatic sampler. Background Technique

[0002] Chromatographic analysis is an analytical technique used to separate, identify, and quantify the components in a mixture. It is based on the distribution differences of different components in the sample between the stationary phase and the mobile phase. Chromatographic analysis is widely used in the fields of chemistry, pharmacy, biology, environmental science, etc., and can analyze complex sample mixtures.

[0003] When injecting samples into a chromatograph, the current existing technology mainly uses a single-channel automatic sampler. Its main structure is that a syringe passes through a low-pressure valve (selector valve) to a high-pressure valve (switching valve) and then to a sample bottle, and after being connected by a pipeline, a certain amount of sample liquid is extracted. After being quantified by a quantitative loop connected to the high-pressure valve, it is switched to the mobile phase for sample injection. Its injection modes can be roughly divided into full quantification (filling the quantitative loop), semi-quantification (any value less than half of the capacity of the quantitative loop, and the accuracy is generally one decimal place), and lossless (filling the pipeline with the mobile phase to achieve the purpose of not wasting samples).

[0004] Its disadvantage is that it cannot inject samples into two liquid chromatographs or ion chromatographs simultaneously. If it is necessary to inject samples into another chromatograph, only by stopping the machine, removing the pipeline and reinstalling it on another chromatograph can it be done, and the same is true when switching back, which will seriously affect the sample analysis efficiency.

[0005] Therefore, we propose a dual-channel liquid automatic sampler to solve the problems raised above. Content of the Utility Model

[0006] (I) Technical Problems to be Solved

[0007] Aiming at the deficiencies of the existing technology in the above background technique, the purpose of the present utility model is to provide a dual-channel liquid automatic sampler to solve the problems raised in the above background technique.

[0008] (II) Technical Solutions

[0009] To achieve the above purposes, the present utility model is realized through the following technical solutions:

[0010] A dual-channel liquid automatic sampler includes a sampler, and a syringe, a Y-shaped three-way valve, a first high-pressure valve, a second high-pressure valve, a sampling needle, and a sample tray are arranged inside the sampler. The syringe, the Y-shaped three-way valve, the first high-pressure valve, the second high-pressure valve, and the sampling needle are sequentially connected through connecting pipelines, and the sample tray is located below the sampling needle;

[0011] Both the first high-pressure valve and the second high-pressure valve are multi-way valves. Quantitative loops are connected to two of the valve ports of the first high-pressure valve and the second high-pressure valve through pipelines, and one of the valve ports on the first high-pressure valve and the second high-pressure valve is respectively connected to the first chromatograph and the second chromatograph.

[0012] Further, the valve ports of the first high-pressure valve include a first valve port a, a first valve port b, a first valve port c, a first valve port d, a first valve port e, and a first valve port f. The valve ports of the second high-pressure valve include a second valve port a, a second valve port b, a second valve port c, a second valve port d, a second valve port e, and a second valve port f. The syringe is connected to the first valve port d, the first valve port c is connected to the second valve port d, and the second valve port c is connected to the sampling needle.

[0013] Further, the first valve port b and the first valve port e are respectively connected to both ends of one of the quantitative loops. The first valve port a is connected to a first liquid phase pump, and the first valve port f is connected to the first chromatograph.

[0014] Further, the second valve port b and the second valve port e are respectively connected to both ends of the other quantitative loop. The second valve port a is connected to a second liquid phase pump, and the second valve port f is connected to the second chromatograph.

[0015] Preferably, a pressure sensor is provided on the pipeline between the syringe and the Y-shaped three-way valve.

[0016] Preferably, the pipeline between the pressure sensor and the first valve port d is a buffer tube.

[0017] (III) Beneficial effects

[0018] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0019] This device can directly inject samples into two sets of chromatographs without repeatedly replacing the pipelines and reconnecting them, avoiding potential hidden dangers caused during the replacement process, such as liquid leakage and equipment damage. It can directly reduce the workload of users in replacing equipment and significantly reduce the working time. For example, if there are originally two sets of chromatographs and 100 samples need to be detected separately, 100 samples need to be detected with two sets of chromatographs respectively. If this structure is used, two sets of chromatographs can simultaneously detect 100 samples, which is more conducive to comparing the detection results, doubling the efficiency, and achieving the purpose of cost reduction and efficiency improvement. Description of the drawings

[0020] Figure 1 is a schematic structural diagram of the dual-channel liquid automatic sampler of the present utility model;

[0021] Figure 2 is a schematic structural diagram of the connection method of the dual-channel liquid automatic sampler of the present utility model.

[0022] In the figure: sampler 1, syringe 2, Y-shaped three-way valve 3, pressure sensor 4, first high-pressure valve, first valve port a51, first valve port b52, first valve port c53, first valve port d54, first valve port e55, first valve port f56, second high-pressure valve 6, second valve port a61, second valve port b62, second valve port c63, second valve port d64, second valve port e65, second valve port f66, quantitative loop 7, sampling needle 8, sample tray 9. Specific embodiments

[0023] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. It should be noted that the terms "front", "rear", "left", "right", "upper" and "lower" used in the following description refer to the directions in the drawings, and the terms "bottom surface" and "top surface", "inner" and "outer" respectively refer to the directions facing or away from the geometric center of a specific component. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts belong to the scope of protection of the present invention.

[0024] Please refer to Figure 1-2 As shown, the present invention provides a dual-channel liquid auto-sampler, including a sampler 1. Inside the sampler 1, there are a syringe 2, a Y-shaped three-way valve 3, a first high-pressure valve 5, a second high-pressure valve 6, a sampling needle 8, and a sample tray 9. The syringe 2, the Y-shaped three-way valve 3, the first high-pressure valve 5, the second high-pressure valve 6, and the sampling needle 8 are all connected in sequence through connecting pipes. The sample tray 9 is located below the sampling needle 8. Both the first high-pressure valve 5 and the second high-pressure valve 6 are multi-way valves, preferably six-way valves.

[0025] The valve ports of the first high-pressure valve 5 include a first valve port a51, a first valve port b52, a first valve port c53, a first valve port d54, a first valve port e55, and a first valve port f56. The valve ports of the second high-pressure valve 6 include a second valve port a61, a second valve port b62, a second valve port c63, a second valve port d64, a second valve port e65, and a second valve port f66. The syringe 2 is connected to the first valve port d54. The first valve port c53 is connected to the second valve port d64. The first valve port b52 and the first valve port e55 are respectively connected to both ends of one of the quantitative loops 7. The first valve port a51 is connected to a first liquid phase pump. The first valve port f56 is connected to a first chromatograph. The second valve port b62 and the second valve port e65 are respectively connected to both ends of the other quantitative loop 7. The second valve port a61 is connected to a second liquid phase pump. The second valve port f66 is connected to a second chromatograph. The second valve port c63 is connected to the sampling needle 8.

[0026] As a preferred technical solution of the present utility model: a pressure sensor 4 is provided on the pipeline between the syringe 2 and the Y-shaped three-way valve 3, and a buffer tube can be used for the pipeline between the pressure sensor 4 and the first valve port d54.

[0027] As a preferred technical solution of the present utility model: one of the valve ports of the Y-shaped three-way valve 3 is connected to an external cleaning solvent pipeline to clean the connecting pipeline and the valve body.

[0028] Through this connection, the two high-pressure valves, namely the first high-pressure valve 5 and the second high-pressure valve 6, can be connected to two sets of chromatographic equipment at the same time to achieve dual-channel automatic injection. The injection operation process is as follows: the second high-pressure valve 6 is switched to the 12-way position, the first high-pressure valve 5 is switched to the 12-way position, and the Y-shaped three-way valve 3 is switched to the cleaning solvent mobile phase position → the syringe 1 draws the cleaning solvent mobile phase → the Y-shaped three-way valve 3 is switched to the high-pressure valve position → the syringe 1 pushes out the cleaning solvent mobile phase to remove air bubbles and clean the pipeline. Repeat this cycle until the set value is reached → the two high-pressure valves are switched to the 16-way position → the syringe 1 is switched to the high-pressure valve position → the syringe 1 draws the set injection volume → the two high-pressure valves are switched to the 12-way position to complete the injection.

[0029] For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific circumstances; for those skilled in the art, they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements on some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present utility model shall be included within the protection scope of the present utility model.

Claims

1. A dual-channel liquid automatic sampler, comprising a sampler (1), characterized in that: The sample injector (1) is provided with a syringe (2), a Y-shaped three-way valve (3), a first high-pressure valve (5), a second high-pressure valve (6), a sampling needle (8) and a sample tray (9); the syringe (2), the Y-shaped three-way valve (3), the first high-pressure valve (5), the second high-pressure valve (6) and the sampling needle (8) are all connected in sequence through a connecting pipe; the sample tray (9) is located below the sampling needle (8); The first high-pressure valve (5) and the second high-pressure valve (6) are both multi-way valves, two valve ports of the first high-pressure valve (5) and the second high-pressure valve (6) are connected to a quantitative ring (7) via a pipeline, and one valve port on the first high-pressure valve (5) and the second high-pressure valve (6) is connected to the first chromatograph and the second chromatograph respectively.

2. A dual-channel liquid automatic sample injector according to claim 1, characterized in that: The valve ports of the first high-pressure valve (5) include a first valve port a (51), a first valve port b (52), a first valve port c (53), a first valve port d (54), a first valve port e (55) and a first valve port f (56); the valve ports of the second high-pressure valve (6) include a second valve port a (61), a second valve port b (62), a second valve port c (63), a second valve port d (64), a second valve port e (65) and a second valve port f (66); the syringe (2) is connected to the first valve port d (54), the first valve port c (53) is connected to the second valve port d (64), and the second valve port c (63) is connected to the sampling needle (8).

3. A dual-channel liquid automatic sample injector according to claim 2, characterized in that: The first valve port b (52) and the first valve port e (55) are respectively connected to two ends of one of the quantitative rings (7), the first valve port a (51) is connected to a first liquid phase pump, and the first valve port f (56) is connected to a first chromatograph.

4. A dual-channel liquid automatic sample injector according to claim 3, characterized in that: The second valve port b (62) and the second valve port e (65) are respectively connected to two ends of another quantitative loop (7), the second valve port a (61) is connected to a second liquid phase pump, and the second valve port f (66) is connected to a second chromatograph.

5. A dual-channel liquid automatic sample injector according to claim 1, characterized in that: A pressure sensor (4) is provided on the pipeline between the syringe (2) and the Y-shaped three-way valve (3).

6. A dual-channel liquid automatic sample injector according to claim 5, characterized in that: The pipeline between the pressure sensor (4) and the first valve port d (54) is a buffer tube.

7. A dual-channel liquid automatic sample injector according to claim 1, characterized in that: One of the valve ports of the Y-shaped three-way valve (3) is connected to an external cleaning solvent pipeline.

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