Column oven of liquid chromatograph column

Abstract

The utility model discloses a column oven for a liquid chromatograph column. The column oven comprises an oven body and a protective sleeve arranged in the oven body, a plurality of protective sleeves are arranged, mounting grooves for mounting chromatographic instrument columns are formed in the protective sleeves, the protective sleeves are detachably connected to the inner side of a rear back plate of the box body, and each protective sleeve comprises a heat conduction layer and a heat preservation layer which are arranged inside and outside; a temperature adjusting module is arranged at the bottom of the box body, and the temperature adjusting module is correspondingly arranged at the bottom of the protective sleeve; the bottom of the protective sleeve is connected with the temperature adjusting module. According to the column oven for the liquid chromatograph columns, the protective jackets matched with the liquid chromatograph columns in number are arranged in the column oven, and the protective jackets are correspondingly connected with the temperature adjusting modules respectively, so that the temperature of the liquid chromatograph columns in the respective mounting grooves is kept in an independent space; the temperature of each liquid chromatograph column is determined by the temperature of each protective sleeve and is not influenced by a column oven.

Description

Technical Field

[0001] The present application relates to a column oven for a liquid chromatograph, belonging to the technical field of liquid chromatographs. Background Art

[0002] At present, a column oven of a chromatograph is a device for controlling the temperature of a chromatographic column, and is usually used for gas chromatography and liquid chromatography analysis. The column oven of a chromatograph can stably control the temperature of the chromatographic column to ensure the accuracy and repeatability of the analysis results. It usually has a temperature adjustment function and can perform analysis at different temperatures to meet different analysis requirements. The existing liquid column oven usually adjusts the temperature of the chromatographic column installed in the column oven by adjusting the temperature of the space inside the column oven. The defect of this temperature adjustment method is that for a column oven equipped with multiple chromatographic columns, when using one of them, it is necessary to open the door of the column oven, and the temperature inside the column oven is easily affected by the outside world, resulting in the inability of another temporarily unnecessary chromatographic column to maintain the required temperature. Content of the Utility Model

[0003] In view of this, the present application provides a column oven for a liquid chromatograph column to solve the problem in the above-mentioned prior art that for a column oven equipped with multiple chromatograph columns, the temperature of the chromatograph column is easily affected by the temperature inside the column oven, resulting in the inability to always maintain a constant temperature. The specific solution is as follows:

[0004] A column oven for a liquid chromatograph column includes: a box body and a protective sleeve arranged inside the box body;

[0005] A plurality of the protective sleeves are provided, and an installation groove for installing a chromatograph column is arranged inside the protective sleeve. The protective sleeve is detachably connected to the inner side of the rear panel of the box body. The protective sleeve includes a heat-conducting layer and a heat-insulating layer arranged inside and outside;

[0006] A temperature adjustment module is arranged at the bottom of the box body, and the temperature adjustment module is correspondingly arranged at the bottom of the protective sleeve;

[0007] The bottom of the protective sleeve is connected to the temperature adjustment module.

[0008] Preferably, the protective sleeve includes two semi-cylindrical bodies arranged in a mirror image, a base and a cylinder cover;

[0009] The base is connected to the temperature adjustment module;

[0010] The two semi-cylindrical bodies are arranged with their openings facing each other and are detachably connected to form a complete cylindrical structure. The bottoms of the two semi-cylindrical bodies are inserted into the base, and the side of the semi-cylindrical body close to the rear panel of the box body facing away from the opening is detachably connected to the rear panel of the box body;

[0011] The cylinder cover is threadedly connected to the top of the cylinder.

[0012] Preferably, a plurality of connecting parts are arranged along the axial direction of the semi-cylindrical body on one side where the openings of the two semi-cylindrical bodies face each other;

[0013] The connecting part includes an insertion block located on one of the semi-cylindrical bodies and a slot correspondingly arranged at the opening of the other semi-cylindrical body;

[0014] One side of the insertion block is fixedly connected to the semi-cylindrical body, and the other side of the insertion block is inserted into the slot to realize the connection of the two semi-cylindrical bodies.

[0015] Preferably, fixing holes are correspondingly arranged on the insertion block and the slot, and fixing columns are arranged on the fixing holes;

[0016] The fixing column is located on the semi-cylindrical body on the side where the slot is arranged. The fixing column is perpendicular to the semi-cylindrical body and is movably connected to the semi-cylindrical body to realize the fixation of the slot and the insertion block.

[0017] Preferably, the fixing column is in a cross shape. One end of the horizontal rod on the fixing column is vertically inserted into the outer wall of the slot, the other end of the horizontal rod of the fixing column faces the inner wall of the slot, and the vertical rod of the fixing column is located inside the outer wall of the slot;

[0018] A spring is arranged between the vertical rod of the fixing column and the outer wall of the slot;

[0019] Both ends of the spring are respectively connected to the vertical rod of the fixing column and the outer wall of the slot;

[0020] One end of the horizontal rod of the fixing column facing the inner wall of the slot is respectively inserted into the fixing hole to realize the fixation of the slot and the insertion block.

[0021] Preferably, external threads are correspondingly arranged at the tops of the two semi-cylindrical bodies;

[0022] Internal threads matching the external threads are arranged inside the cylinder cover.

[0023] Preferably, the two semi-cylindrical bodies are transparent cylinders.

[0024] Preferably, the temperature adjustment modules are controlled separately.

[0025] The beneficial effects that can be produced by this application include:

[0026] The column oven of the liquid chromatograph provided by this application is internally provided with protective sleeves that match the number of liquid chromatograph columns. Each of the protective sleeves is respectively connected to a temperature adjustment module, so as to ensure that the temperature of the liquid chromatograph column in each installation slot is in a separate space. The temperature of each liquid chromatograph column is determined by the temperature of each protective sleeve and is not affected by the column oven. Moreover, the temperature adjustment module is controlled separately to achieve flexible adjustment of the temperature of each liquid chromatograph column. Description of the Drawings

[0027] Figure 1 It is a three-dimensional schematic diagram of a column oven of a liquid chromatograph column of this application;

[0028] Figure 2 It is a side view of a column oven of a liquid chromatograph column of this application;

[0029] Figure 3 For Figure 2 It is an enlarged cross-sectional schematic diagram at position A in

[0030] Figure 4 It is a connection schematic diagram of the fixed column in a column oven of a liquid chromatograph column of this application.

[0031] List of components and reference numerals:

[0032] 1. Rear panel of the box body; 2. Base of the box body; 3. Protective sleeve; 4. Temperature adjustment module; 5. Hanging hole; 6. Hanging rack; 7. Cylinder cover; 31. First semi-cylindrical body; 32. Insert block; 33. Second semi-cylindrical body; 34. Fixed column; 35. Spring. Detailed Description of the Invention

[0033] The following describes this application in detail with reference to the embodiments, but this application is not limited to these embodiments.

[0034] According to Figures 1-4 A column oven of a liquid chromatograph column as shown, including: a box body and a protective sleeve arranged inside the box body;

[0035] A plurality of the protective sleeves are provided. An installation slot for installing a chromatograph column is arranged inside the protective sleeve 3. The protective sleeve is detachably connected to the inner side of the rear panel 1 of the box body. The protective sleeve includes a heat-conducting layer and a heat-insulating layer arranged inside and outside;

[0036] A temperature adjustment module 4 is arranged at the bottom of the box body. The temperature adjustment module 4 is correspondingly arranged at the bottom of the protective sleeve 3;

[0037] The bottom of the protective sleeve is connected to the temperature adjustment module.

[0038] Furthermore, the protective sleeve includes two semi-cylindrical bodies, a base and a cylinder cover that are arranged in a mirror image;

[0039] The base is connected to the temperature regulation module;

[0040] The two semi-cylindrical bodies are arranged with their openings facing each other and are detachably connected to form a complete cylindrical structure. The bottoms of the two semi-cylindrical bodies are inserted into the base 2 of the box body, and the side of the semi-cylindrical body (i.e., the second semi-cylindrical body 33) close to the back panel of the box body is detachably connected to the back panel of the box body;

[0041] Among them, the detachable connection between the second semi-cylindrical body 33 and the back panel of the box body is realized through an L-shaped hanger 6 with an opening downward and an elongated hanging hole 5. The elongated hanging hole 5 is arranged on the back panel of the box body, and the positions of the hanger 6 and the elongated hanging hole 5 correspond to each other. One end of the hanger 6 is fixedly connected to the second semi-cylindrical body 33, and the other end of the hanger 6 is hung on the elongated hanging hole 5;

[0042] The cylinder cover 7 is threadedly connected to the top of the cylinder.

[0043] Furthermore, a plurality of connecting parts are arranged along the axial direction of the semi-cylindrical bodies on the side where the openings of the two semi-cylindrical bodies face each other;

[0044] The connecting part includes an insertion block 32 located on one of the semi-cylindrical bodies (i.e., the first semi-cylindrical body 31) and a slot correspondingly arranged at the opening of the other semi-cylindrical body (i.e., the second semi-cylindrical body 33); the insertion block 32 and the slot are respectively arranged along the axial direction of the semi-cylindrical body;

[0045] One side of the insertion block 32 is fixedly connected to the semi-cylindrical body, and the other side of the insertion block 32 is inserted into the slot to realize the connection of the two semi-cylindrical bodies.

[0046] Furthermore, fixing holes are correspondingly arranged on the insertion block 32 and the slot, and fixing columns 34 are arranged on the fixing holes;

[0047] The fixing column 34 is located on the semi-cylindrical body on the side where the slot is arranged. The fixing column is perpendicular to the semi-cylindrical body and is movably connected to the semi-cylindrical body to realize the fixation of the slot and the insertion block 32.

[0048] Furthermore, the fixing column 34 is in a cross shape. One end of the horizontal rod on the fixing column 34 is vertically inserted into the outer wall of the slot, the other end of the horizontal rod of the fixing column 34 faces the inner wall of the slot, and the vertical rod of the fixing column 34 is located inside the outer wall of the slot;

[0049] A spring 35 is arranged between the vertical rod of the fixing column 34 and the outer wall of the slot;

[0050] Both ends of the spring 35 are respectively connected to the vertical rod of the fixing column and the outer wall of the slot;

[0051] One end of the horizontal rod of the fixed column 34 facing the inner wall of the slot is inserted into the fixing hole respectively, so as to fix the slot and the plug block.

[0052] Furthermore, external threads are respectively arranged corresponding to the tops of the two semi-cylindrical bodies.

[0053] Internal threads matching the external threads are arranged in the cylinder cover 7.

[0054] Furthermore, the two semi-cylindrical bodies are respectively transparent cylindrical bodies.

[0055] Furthermore, the temperature regulation modules are controlled separately.

[0056] When placing the liquid chromatography column, first, place the liquid chromatography column on the inner wall of the second semi-cylindrical body 33, then buckle the first semi-cylindrical body 31 on the opening of the second semi-cylindrical body 33, pull out the fixed column 34 outwards. At this time, the spring 35 is in a compressed state. After the plug block 32 is completely inserted into the slot, release the fixed column 34, and the spring 35 releases, so that the plug block 32 is fixed in the slot. When taking out the liquid chromatography column, the operation is just the opposite.

[0057] It should be noted that:

[0058] In this application, the box body is composed of a bottom plate, the wall plates on both sides of the back plate, a top plate and a box door in front of the box body. The back plate includes a load-bearing plate and a connecting plate provided with long hanging holes 5 on both sides. The connecting plate and the load-bearing plate are arranged with a gap and are respectively fixedly connected to the side plate, the wall plate, the top plate and the cover plate; the protective sleeve is hung on the connecting plate through a hanging bracket 6;

[0059] An installation cavity is arranged on the bottom plate. The temperature regulation module includes a temperature sensor arranged on one side of the heat conduction plate facing the liquid chromatography column, a heating plate embedded with a heating coil, and a temperature controller installed in the installation cavity;

[0060] The heating plate is located above the temperature regulation module. The heating plate contacts the bottom of the protective sleeve. The heating coil and the temperature sensor in the heating plate are respectively connected to the temperature controller; among them, the model of the temperature controller is: OHR-A303C-02-K4 / X-A; the model of the temperature sensor is: RKC physical and chemical thermocouple ST-50.

[0061] The protective sleeve includes a heat conduction layer and a heat insulation layer which are fixedly connected. The heat conduction layer is a heat conduction plate to achieve uniform heating, and the heat insulation layer is a heat insulation plate.

[0062] As described above, these are only several embodiments of the present application and do not impose any form of limitation on the present application. Although the present application is disclosed with preferred embodiments as above, it is not intended to limit the present application. Any person skilled in the relevant art can make some changes or modifications within the scope of the technical solution of the present application by using the disclosed technical content, and these are all equivalent to equivalent embodiments and fall within the scope of the technical solution.

Claims

1. A liquid chromatograph column oven, characterized in that: include: A box body and a protective cover arranged in the box body; There are several protective covers, each of which has an installation slot for installing a chromatograph column. The protective cover is detachably connected to the inner side of the back plate of the box, and the protective cover includes a heat-conducting layer and a heat-insulating layer arranged inside and outside. A temperature regulating module is disposed at the bottom of the box body, and the temperature regulating module is correspondingly disposed at the bottom of the protective cover; The bottom of the protective cover is connected to the temperature regulating module.

2. A liquid chromatograph column oven according to claim 1, characterized in that: The protective cover comprises two semi-cylinders arranged in mirror image, a base and a cylinder cover; The base is connected to the temperature adjustment module; The openings of the two semi-cylinders are arranged opposite to each other and are detachably connected to form a complete cylinder structure. The bottoms of the two semi-cylinders are plugged into the base, and the side of the semi-cylinder close to the back plate of the box body facing away from the opening is detachably connected to the back plate of the box body. The cylinder cover is threadedly connected to the top of the cylinder body.

3. A liquid chromatograph column oven according to claim 2, characterized in that: A connecting portion is provided on one side of the openings of the two semi-cylinders opposite to each other along the axial direction of the semi-cylinders; The connecting part includes an insert block located on one of the semi-cylindrical bodies, and a slot correspondingly arranged at the opening of the other semi-cylindrical body; The slots and the inserts are respectively arranged along the axial direction of the semi-cylinder; One side of the insert block is fixedly connected to the semi-cylinder, and the other side of the insert block is inserted into the slot to achieve the connection between the two semi-cylinders.

4. A liquid chromatograph column oven according to claim 3, characterized in that: The plug block and the slot are respectively provided with fixing holes, and the fixing holes are provided with fixing columns; The fixing column is located on a semi-cylindrical body at one side of the slot, and the fixing column is perpendicular to the semi-cylindrical body and movably connected to the semi-cylindrical body to fix the slot and the insert block.

5. A liquid chromatograph column oven according to claim 4, characterized in that: The fixing column is cross-mounted, one end of the horizontal rod on the fixing column is vertically inserted into the slot wall outside the slot, the other end of the horizontal rod of the fixing column faces the slot wall inside the slot, and the vertical rod of the fixing column is located on the inner side of the slot wall outside the slot; A spring is provided between the vertical rod of the fixing column and the slot wall outside the slot; The two ends of the spring are respectively connected to the vertical rod of the fixing column and the slot wall outside the slot; One end of the horizontal rod of the fixing column facing the slot wall inside the slot is respectively inserted into the fixing hole to fix the slot and the insert block.

6. A liquid chromatograph column oven according to claim 2, characterized in that: The tops of the two semi-cylindrical bodies are respectively provided with external threads; The cylinder cover is provided with an internal thread matching the external thread.

7. A liquid chromatograph column oven according to claim 2, characterized in that: The two semi-cylindrical bodies are respectively transparent cylinders.

8. The liquid chromatograph column oven according to claim 1, characterized in that: The temperature regulating modules are controlled separately.

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