Combined detection card for disease markers

Abstract

The utility model discloses a disease marker joint detection card which comprises an antigen detection card, a sample adding hole is formed in one end of the upper surface of the antigen detection card, and a display observation hole is formed in the other end, located at the sample adding hole, of the upper surface of the antigen detection card. A colloidal gold test card is arranged on the inner side of the antigen detection card at the sample adding hole and the display observation hole, a detection line T and a quality control line C are sequentially arranged on the colloidal gold test card, and a protective sliding cover is further mounted at the top of the antigen detection card; when the device is used for detection and the antigen detection card is taken out, the protective sliding cover can cover right above the sample adding hole and the display observation hole in a sliding manner, and when the device is used for detection, the protective sliding cover is ripped open, a test solution is dropped in, and then the protective sliding cover covers the surface of the antigen detection card again; the possibility that dust, viruses and the like in the air fall on the colloidal gold test card during detection is reduced, and the practicability of the test card is improved.

Description

Technical Field

[0001] The utility model belongs to the technical field of detection cards, and particularly relates to a combined detection card for disease markers. Background Art

[0002] A combined detection card for disease markers is a tool for simultaneously detecting multiple biomarkers related to a specific disease. The design of this detection card enables doctors to diagnose diseases more quickly and accurately, and monitor the progression and treatment effect of diseases. It usually includes multiple detection card slots, and each slot is embedded with a different detection card for detecting different disease markers. By simultaneously detecting multiple markers, doctors can obtain more comprehensive disease information and improve the accuracy and efficiency of diagnosis.

[0003] In the patent with the application number 201621385116.2, a combined detection card for markers in the acute exacerbation period of chronic obstructive pulmonary disease is disclosed. This application can simultaneously detect three items: total C-reactive protein (CRP), procalcitonin (PCT), and N-terminal pro-brain natriuretic peptide (NT-proBNP) to help doctors quickly and conveniently diagnose and treat patients in the acute exacerbation period of chronic obstructive pulmonary disease (COPD). Combining the above application with the existing detection cards, when using the existing combined detection card for detection, during the use process, when the test solution is dropped into the detection card, both the liquid hole and the display observation hole on the detection card are exposed. During the reaction process, it is possible for dust and viruses in the air to fall on the colloidal gold test card, affecting the detection accuracy and thus the practicality of the detection card. For this reason, we propose a combined detection card for disease markers. Summary of the Utility Model

[0004] The purpose of the utility model is to provide a combined detection card for disease markers to solve the problem proposed in the above background art that when using the existing combined detection card for detection, during the use process, when the test solution is dropped into the detection card, both the liquid hole and the display observation hole on the detection card are exposed. During the reaction process, it is possible for dust and viruses in the air to fall on the colloidal gold test card, affecting the detection accuracy and thus the practicality of the detection card.

[0005] To achieve the above object, the present utility model provides the following technical solution: A combined detection card for disease markers, including an antigen detection card. One end of the upper surface of the antigen detection card is provided with a sample addition hole, and the other end of the upper surface of the antigen detection card, located at the other end of the sample addition hole, is provided with a display observation hole. Inside the antigen detection card, at the positions of the sample addition hole and the display observation hole, a colloidal gold test card is provided. On the colloidal gold test card, a detection line T and a quality control line C are sequentially arranged. At the top of the antigen detection card, a protective sliding cover is further installed. At the bottom of the protective sliding cover, a rubber sealing strip is provided. At both sides of the bottom of the protective sliding cover, sliding blocks are provided. On both sides of the antigen detection card, sliding grooves are opened. At the end of the sliding groove, a limiting card slot is provided. At the bottom of the antigen detection card, a preheating groove is provided.

[0006] Preferably, a plurality of colloidal gold test cards are equidistantly arranged inside the antigen detection card, and each colloidal gold test card is provided with a corresponding sample addition hole and display observation hole.

[0007] Preferably, the protective sliding cover and the antigen detection card are slidably installed through the sliding blocks and the sliding grooves, and between the antigen detection card and the protective sliding cover, they are also limited and clamped through the limiting card slots and the sliding blocks.

[0008] Preferably, a breathable non-woven fabric is provided inside the preheating groove, and on one side of the breathable non-woven fabric inside the preheating groove, an iron powder activated carbon filler is filled.

[0009] Preferably, at the bottom of the antigen detection card, directly below the preheating groove, a sealing patch is provided, and on one side of the sealing patch, an easy-to-tear opening is provided.

[0010] Preferably, the preheating groove is located directly below a plurality of the colloidal gold test cards.

[0011] Compared with the prior art, the beneficial effects of the present utility model are:

[0012] (1) Through the structure of the protective sliding cover with sliding opening and closing, when using this device for detection, when the antigen detection card is taken out, the protective sliding cover can be slid and closed directly above the sample addition hole and the display observation hole. When using for detection, the protective sliding cover is slid open, after dropping the test solution, the protective sliding cover is covered on the surface of the antigen detection card again, reducing the possibility of dust and viruses in the air falling on the colloidal gold test card during use, reducing the interference of external factors, improving the accuracy of detection, and at the same time, the structure is simple and easy to use, thus improving the practicality of this detection card;

[0013] (2) During the use of the test card, by setting a constant temperature preheating method at the bottom of the antigen test card directly below the colloidal gold test card, during the use of the test card, the sealing patch at the bottom of the preheating tank can be torn off to make the iron powder activated carbon filler in the preheating tank contact with air, thereby generating a certain amount of heat. The activity of the test solution on the colloidal gold test card can be improved through the generated heat, better manifested, and the detection sensitivity and detection efficiency of the reagent card can be improved, so as to better detect and use. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 is a schematic structural diagram of the present invention;

[0015] Figure 2 is a schematic bottom structural diagram of the protective sliding cover of the present invention;

[0016] Figure 3 is a schematic cross-sectional structural diagram of the antigen test card of the present invention;

[0017] In the figure: 100, antigen test card; 101, sample addition hole; 102, display and observation hole; 103, colloidal gold test card; 104, control line C; 105, test line T; 200, protective sliding cover; 201, slideway; 202, limit card slot; 203, rubber sealing strip; 204, sliding block; 300, preheating tank; 301, iron powder activated carbon filler; 302, breathable non-woven fabric; 303, sealing patch; 304, easy tear opening. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0018] The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0019] Embodiment 1

[0020] Please refer to Figure 1 、 Figure 2 and Figure 3, the present utility model provides a technical solution: The main detection methods adopted by the disease biomarker combined detection card include fluorescence immunochromatography, mass spectrometry analysis technology, two-dimensional gel electrophoresis technology, etc. These methods have the advantages of high sensitivity, high specificity, and rapidity, and can accurately detect disease biomarkers in biological samples. A disease biomarker combined detection card includes an antigen detection card 100. One end of the upper surface of the antigen detection card 100 is provided with a sample addition hole 101, and the other end of the upper surface of the antigen detection card 100 located at the other end of the sample addition hole 101 is provided with a corresponding display observation hole 102. Inside the antigen detection card 100, a colloidal gold test card 103 is arranged at the positions of the sample addition hole 101 and the display observation hole 102. A detection line T105 and a quality control line C104 are sequentially arranged on the colloidal gold test card 103. A protective sliding cover 200 is further installed on the top of the antigen detection card 100. A rubber sealing strip 203 is arranged at the bottom of the protective sliding cover 200. Sliding blocks 204 are arranged on both sides of the bottom of the protective sliding cover 200. Slideways 201 are opened on both sides of the antigen detection card 100, and limit card slots 202 are arranged at the ends of the slideways 201. When using the disease biomarker combined detection card in this application, before use, the protective sliding cover 200 is covered directly above the antigen detection card 100. By covering the protective sliding cover 200, dust, viruses, etc. are prevented from falling into the sample addition hole 101 and the display observation hole 102. When detecting, slide the protective sliding cover 200. The protective sliding cover 200 slides in the slideways 201 on both sides of the antigen detection card 100 through the sliding blocks 204, and when the sliding blocks 204 slide into the limit card slots 202 at the ends of the slideways 201, they are locked in position, thereby ensuring the stability of the protective sliding cover 200. After the test solution is dropped into the sample addition hole 101, slide the protective sliding cover 200 again to cover the surface of the antigen detection card 100 for protection. And the protective sliding cover 200 is made of transparent acrylic material, which is convenient for observation, and can avoid the influence of dust and viruses in the air before and after use, reduce the influence of external factors, and improve the accuracy of detection.

[0021] Specifically, a plurality of colloidal gold test cards 103 are equidistantly arranged inside the antigen detection card 100, and each colloidal gold test card 103 is provided with a corresponding sample addition hole 101 and display observation hole 102. Through the action of multiple antigen detection cards 100, multiple diseases can be detected simultaneously, which is better for detection and comparison. The protective sliding cover 200 and the antigen detection card 100 are slidably installed through the sliding blocks 204 and the slideways 201, and the antigen detection card 100 and the protective sliding cover 200 are also limited and locked through the limit card slots 202 and the sliding blocks 204. While facilitating the sliding adjustment of the protective sliding cover 200, the slid protective sliding cover 200 can also be fixed.

[0022] Embodiment 2

[0023] Please refer toFigure 1 and Figure 3 , the present utility model provides a technical solution: a combined detection card for disease markers. An air-permeable non-woven fabric 302 is fixedly arranged inside the preheating tank 300, and an iron powder activated carbon filler 301 is filled on one side of the air-permeable non-woven fabric 302 in the preheating tank 300. The air-permeable non-woven fabric 302 prevents the iron powder activated carbon filler 301 from spilling. Before using the detection card, the sealing patch 303 at the bottom of the antigen detection card 100 can be torn open through the easy tear opening 304, so that the air-permeable non-woven fabric 302 at the bottom of the preheating tank 300 is exposed to the air. When the air passes through the air-permeable non-woven fabric 302 and contacts the iron powder activated carbon filler 301 filled inside the preheating tank 300, the iron powder activated carbon filler 301 undergoes oxygen absorption corrosion, converting chemical energy into heat energy, thereby providing a certain amount of heat. The heat is conducted to the colloidal gold test card 103, improving the activity of the test solution, accelerating the color development effect, improving the detection efficiency, and thus better detecting and using, improving the practicability of the detection card.

[0024] Specifically, a sealing patch 303 is arranged directly below the preheating tank 300 at the bottom of the antigen detection card 100. An easy tear opening 304 is arranged on one side of the sealing patch 303. The bottom of the preheating tank 300 is hermetically bonded through the sealing patch 303 to prevent the iron powder activated carbon filler 301 in the preheating tank 300 from contacting the air when not in use. The preheating tank 300 is located directly below a plurality of colloidal gold test cards 103, and when the iron powder activated carbon filler 301 in the preheating tank 300 generates heat, it can be better conducted to the colloidal gold test card 103.

[0025] Although the embodiments of the present utility model have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principle and spirit of the present utility model. The scope of the present utility model is defined by the appended claims and their equivalents.

Claims

1. A disease marker combined detection card, comprising an antigen detection card (100), wherein a sample addition hole (101) is provided at one end of the upper surface of the antigen detection card (100), and a display observation hole (102) is provided at the other end of the upper surface of the antigen detection card (100) located at the sample addition hole (101), wherein: A colloidal gold test card (103) is arranged on the inner side of the antigen detection card (100) at the sample addition hole (101) and the display observation hole (102); a detection line T (105) and a quality control line C (104) are arranged in sequence on the colloidal gold test card (103); a protective sliding cover (200) is also installed on the top of the antigen detection card (100); a rubber sealing strip (203) is arranged at the bottom of the protective sliding cover (200); sliding blocks (204) are arranged on both sides of the bottom of the protective sliding cover (200); slideways (201) are opened on both sides of the antigen detection card (100); a limit slot (202) is arranged at the end of the slideway (201); and a preheating slot (300) is arranged at the bottom of the antigen detection card (100).

2. A disease marker combined detection card according to claim 1, characterized in that: A plurality of colloidal gold test cards (103) are equidistantly arranged on the inner side of the antigen detection card (100), and each of the colloidal gold test cards (103) is provided with a corresponding sample addition hole (101) and a display observation hole (102).

3. A disease marker combined detection card according to claim 1, characterized in that: The protective sliding cover (200) and the antigen detection card (100) are slidably mounted via a sliding clamping block (204) and a slideway (201), and the antigen detection card (100) and the protective sliding cover (200) are also limitedly mounted via a limiting clamping groove (202) and a sliding clamping block (204).

4. A disease marker combined detection card according to claim 1, characterized in that: An air-permeable non-woven fabric (302) is arranged inside the preheating tank (300), and an iron powder activated carbon filler (301) is filled on one side of the air-permeable non-woven fabric (302) in the preheating tank (300).

5. A disease marker combined detection card according to claim 4, characterized in that: A sealing patch (303) is provided at the bottom of the antigen detection card (100) directly below the preheating tank (300), and an easy-to-tear opening (304) is provided on one side of the sealing patch (303).

6. A disease marker combined detection card according to claim 4, characterized in that: The preheating tank (300) is located directly below the plurality of colloidal gold test cards (103).

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