Anti-precipitation reagent temporary storage device

By designing a temporary storage device for anti-precipitation reagents and using a driving mechanism to drive the reagent tube to rotate, the problem of magnetic beads/microspheres in the reagent tube is solved, ensuring the consistency of the concentration of the reagent tube and the accuracy of the detection results.

CN222998825UActive Publication Date: 2025-06-20SHENZHEN RUIJING ZHIZAO LIFE TECH CO LTD
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Patent Information

Application Number
CN202422212160.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-10
Publication Date
2025-06-20
Estimated Expiration
2034-09-10

AI Technical Summary

Technical Problem

In chemiluminescence immunoassay, the magnetic beads/microspheres in the reagent tube are prone to precipitation under the action of gravity, resulting in a higher concentration at the bottom of the reagent tube than in the middle, affecting the accuracy of the detection results.

Method used

A temporary storage device for anti-precipitation reagents is designed, including a temporary storage box, a detachable temporary storage rack, a driving assembly and a transmission structure. The beads/microspheres are prevented from precipitation by inserting the reagent tube into the rotation position and driving the reagent tube to rotate using a driving mechanism.

Benefits of technology

It effectively prevents the precipitation of magnetic beads/microspheres in the reagent tube, so that the concentration at the bottom and middle part of the reagent tube is consistent, and improves the accuracy of the detection results.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of medical diagnosis and analysis, in particular to an anti-precipitation reagent temporary storage device which comprises a temporary storage box, a plurality of temporary storage frames, a driving assembly installed on one side of the temporary storage box and a transmission structure installed at the bottom of the temporary storage box. The rotating position and the fixed position are both used for inserting reagent tubes, and the driving mechanism drives the reagent tubes on the rotating position to rotate through the transmission structure; during use, reagent tubes which do not need to be prevented from precipitation are inserted into the fixed positions, reagent tubes which need to be prevented from precipitation are inserted into the rotating positions, and the driving mechanism drives the reagent tubes on the rotating positions to rotate through the transmission structure, so that magnetic beads / microspheres in the reagent tubes are prevented from precipitating at the bottoms of the reagent tubes; magnetic beads / microspheres in a reagent can be effectively prevented from precipitating at the bottom of the reagent tube, so that the concentration of the bottom of the reagent tube is consistent with the concentration of the middle part of the reagent tube, and the accuracy of a detection result after extraction by the extraction head of the detector is ensured.
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Description

Technical Field

[0001] The utility model relates to the technical field of medical diagnosis and analysis, in particular to a reagent temporary storage device for preventing precipitation. Background Technique

[0002] In the immune reaction, a variety of biological reagents such as antigens and antibodies need to be mixed with samples, and then heated and incubated to enable the combination of antigens and antibodies. In chemiluminescence immunoassay, the magnetic particle complex formed by the combination of antigens, antibodies, and magnetic particles is a carrier of the signal to be measured; in the process of such chemiluminescence immunoassay, reagent pipetting or temporary storage of reagents is often required according to different stages or detection requirements. For example, a Chinese patent with the authorized announcement number CN220549490U discloses a reagent temporary storage component for a detector; it includes a temporary storage rack board, a temporary storage upper cover, a light-shielding pull plate, a reagent rack body, a refrigeration module, and a pull plate motor; auxiliary vertical bars are arranged on the inner wall of the temporary storage rack board; the temporary storage upper cover is covered and fixed above the auxiliary vertical bars; the reagent rack body is assembled below the temporary storage upper cover through the auxiliary vertical bars; the refrigeration module is arranged below the reagent rack body; one end of the light-shielding pull plate is inserted into the temporary storage upper cover, and the other end is connected to a traction spring piece; the pull plate motor is fixed on the inner wall of the temporary storage rack board, and its output end is connected to and drives the light-shielding pull plate; by adopting the utility model, the protection and shielding of the reagent tube are realized through the pullable and movable light-shielding pull plate, ensuring that the reagent is not contaminated by light sources and other impurities during the temporary storage process in the reagent tube, improving the accuracy of the overall detection or reading; and a refrigeration module is additionally configured to protect the activity of the reagent, ensuring the quality of the reagent and improving the detection efficiency and accuracy.

[0003] However, in practical applications, the above reagent temporary storage component still has the following deficiencies: Since the components of the reagent are relatively complex, some reagents contain magnetic beads / microspheres. Under the action of gravity, the magnetic beads / microspheres will precipitate at the bottom of the reagent tube, resulting in a situation where the concentration at the bottom of the reagent tube is higher than that in the middle of the reagent tube, affecting the accuracy of the detection result after the extraction head of the detector extracts. Summary of the Utility Model

[0004] The purpose of the utility model is to provide a reagent temporary storage device for preventing precipitation in view of the above deficiencies, which can effectively prevent the magnetic beads / microspheres in the reagent from precipitating at the bottom of the reagent tube, making the concentration at the bottom of the reagent tube the same as that in the middle of the reagent tube, and ensuring the accuracy of the detection result after the extraction head of the detector extracts.

[0005] In order to achieve the above purpose, the utility model adopts the following technical scheme:

[0006] A temporary storage device for anti-precipitation reagent, comprising a temporary storage box, a plurality of temporary storage racks detachably connected in the temporary storage box, a driving component installed on one side of the temporary storage box, and a transmission structure installed at the bottom of the temporary storage box. A rotating position and a plurality of fixed positions are arranged on the temporary storage rack, and both the rotating position and the fixed positions are used for inserting reagent tubes. The driving mechanism drives the reagent tube on the rotating position to rotate through the transmission structure.

[0007] Further, a connecting ring is coaxially connected to the bottom of the reagent tube, and a plurality of convex strips connecting the reagent tube are radially arranged on the connecting ring; the transmission structure includes a plurality of driven gears rotatably connected to the bottom of the temporary storage box, adjacent driven gears are meshed with each other, a cylindrical connecting seat is arranged on the driven gear, and an insertion hole is arranged on the connecting seat opposite to the connecting ring. The insertion hole is connected to the outer side wall of the connecting seat through a plurality of slot holes, and the driving component is used to drive the rightmost driven gear to rotate.

[0008] Further, an opening is arranged on one side of the temporary storage box; the driving component includes a motor installed on one side of the temporary storage box, a driving gear arranged on the output shaft of the motor, and the driving gear is meshed with the rightmost driven gear through the opening.

[0009] Further, a plurality of cushion blocks are arranged at the bottom of the temporary storage box, and the cushion blocks are arranged directly below the fixed positions.

[0010] Further, one side of the temporary storage rack is an arc surface, the other side of the temporary storage rack is a plane, and the arc surface is arranged close to the rotating position.

[0011] The beneficial effects of the present utility model are:

[0012] In practical applications, during use, the reagent tubes that do not need to prevent precipitation are inserted into the fixed positions, and the reagent tubes that need to prevent precipitation are inserted into the rotating positions. The driving mechanism drives the reagent tubes on the rotating positions to rotate through the transmission structure, preventing the magnetic beads / microspheres in the reagent tubes from precipitating at the bottom of the reagent tubes; the present utility model can effectively prevent the magnetic beads / microspheres in the reagent from precipitating at the bottom of the reagent tubes, making the concentration at the bottom of the reagent tube consistent with the concentration in the middle of the reagent tube, ensuring the accuracy of the detection results after the extraction head of the detector extracts. Description of the Drawings

[0013] Figure 1 is the overall structural schematic diagram of the present utility model;

[0014] Figure 2 is the structural schematic diagram inside the temporary storage box of the present utility model;

[0015] Figure 3 is the top view inside the temporary storage box of the present utility model;

[0016] Figure 4 It is a schematic structural diagram of the driven gear in the present utility model;

[0017] Figure 5 It is a schematic structural diagram of the reagent tube in the present utility model;

[0018] Reference numerals: temporary storage box 1; cushion block 11; temporary storage rack 2; rotation position 21; fixed position 22; arc surface 23; flat surface 24; reagent tube 3; connecting ring 31; convex strip 32; driven gear 41; connecting seat 42; jack 43; slot 44; motor 51; driving gear 52. Detailed implementation manners

[0019] As Figure 1 、 Figure 2 、 Figure 3 、 Figure 4 and Figure 5 shown, an anti-precipitation reagent temporary storage device includes a temporary storage box 1, a plurality of temporary storage racks 2 detachably connected in the temporary storage box 1, a driving assembly installed on one side of the temporary storage box 1, and a transmission structure installed at the bottom of the temporary storage box 1. A rotation position 21 and a plurality of fixed positions 22 are provided on the temporary storage rack 2. Both the rotation position 21 and the fixed positions 22 are used for inserting the reagent tube 3, and the driving mechanism drives the reagent tube 3 on the rotation position 21 to rotate through the transmission structure.

[0020] During use, insert the reagent tubes 3 that do not need to prevent precipitation into the fixed positions 22, and insert the reagent tubes 3 that need to prevent precipitation into the rotation position 21. The driving mechanism drives the reagent tubes 3 on the rotation position 21 to rotate through the transmission structure, preventing the magnetic beads / microspheres in the reagent tubes 3 from precipitating at the bottom of the reagent tubes 3. The present utility model can effectively prevent the magnetic beads / microspheres in the reagent from precipitating at the bottom of the reagent tube 3, making the concentration at the bottom of the reagent tube 3 the same as the concentration in the middle of the reagent tube 3, and ensuring the accuracy of the detection result after the extraction head of the detector extracts.

[0021] As Figure 1 、 Figure 2 、 Figure 3 、 Figure 4 and Figure 5As shown, a connecting ring 31 is coaxially connected to the bottom of the reagent tube 3, and a plurality of ribs 32 connecting the reagent tube 3 are radially arranged on the connecting ring 31; the transmission structure includes a plurality of driven gears 41 rotatably connected to the bottom of the temporary storage box 1, and adjacent driven gears 41 are meshed with each other. A cylindrical connecting seat 42 is arranged on the driven gear 41, and a jack 43 is arranged on the connecting seat 42 opposite to the connecting ring 31. The jack 43 is connected to the outer side wall of the connecting seat 42 through a plurality of slots 44. The driving component is used to drive the rightmost driven gear 41 to rotate; in this embodiment, when the reagent tube 3 is inserted into the rotating position 21, the connecting ring 31 is inserted into the jack 43, and the rib 32 is inserted into the slot 44. During the process of the driving component driving the driven gear 41 to rotate, the driven gear 41 drives the connecting ring 31 and the reagent tube 3 on the connecting seat 42 to rotate.

[0022] As Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5 As shown, an opening is arranged on one side of the temporary storage box 1; the driving component includes a motor 51 installed on one side of the temporary storage box 1, and a driving gear 52 arranged on the output shaft of the motor 51. The driving gear 52 is meshed with the rightmost driven gear 41 through the opening; in this embodiment, the motor 51 drives the driving gear 52 to drive the driven gear 41 to rotate.

[0023] As Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5 As shown, a plurality of cushion blocks 11 are arranged at the bottom of the temporary storage box 1, and the cushion blocks 11 are arranged directly below the fixing position 22; in this embodiment, when the reagent tube 3 is inserted into the fixing position 22, the bottom end of the reagent tube 3 abuts against the cushion block 11.

[0024] As Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5 As shown, one side of the temporary storage rack 2 is an arc surface 23, and the other side of the temporary storage rack 2 is a flat surface 24. The arc surface 23 is arranged close to the rotating position 21; in this embodiment, by respectively arranging the two sides of the temporary storage rack 2 as the arc surface 23 and the flat surface 24, it is used to prevent the temporary storage rack 2 from being installed in the wrong direction in the temporary storage box 1.

[0025] The specific embodiments described herein are merely illustrative of the present invention. Those skilled in the art of the present invention can make various modifications or supplements to the described specific embodiments or use similar methods to replace them, but will not deviate from the scope defined by the present invention.

Claims

1. A temporary storage device for anti-precipitation reagents, characterized in that: The invention comprises a temporary storage box (1), a plurality of temporary storage racks (2) detachably connected to the temporary storage box (1), a driving component installed on one side of the temporary storage box (1), and a transmission structure installed on the bottom of the temporary storage box (1); the temporary storage rack (2) is provided with a rotating position (21) and a plurality of fixed positions (22); the rotating position (21) and the fixed positions (22) are both used for inserting reagent tubes (3); the driving component drives the reagent tubes (3) on the rotating position (21) to rotate through the transmission structure.

2. The anti-precipitation reagent temporary storage device according to claim 1, characterized in that: The bottom of the reagent tube (3) is coaxially connected to a connecting ring (31), and the connecting ring (31) is radially provided with a plurality of convex strips (32) connected to the reagent tube (3); the transmission structure comprises a plurality of driven gears (41) rotatably connected to the bottom of the temporary storage box (1), and adjacent driven gears (41) are meshed with each other, and a cylindrical connecting seat (42) is provided on the driven gear (41), and a plug hole (43) is provided on the connecting seat (42) facing the connecting ring (31), and the plug hole (43) is connected to the outer wall of the connecting seat (42) through a plurality of slots (44), and the driving assembly is used to drive the rightmost driven gear (41) to rotate.

3. The temporary storage device for anti-precipitation reagent according to claim 2, characterized in that: An opening is provided on one side of the temporary storage box (1); the driving assembly comprises a motor (51) mounted on one side of the temporary storage box (1), and a driving gear (52) arranged on an output shaft of the motor (51); the driving gear (52) meshes with the rightmost driven gear (41) through the opening.

4. The anti-precipitation reagent temporary storage device according to claim 1, characterized in that: A plurality of cushion blocks (11) are arranged at the bottom of the temporary storage box (1), and the cushion blocks (11) are arranged directly below the fixing position (22).

5. The anti-precipitation reagent temporary storage device according to claim 1, characterized in that: One side of the temporary storage rack (2) is a circular arc surface (23), and the other side of the temporary storage rack (2) is a flat surface (24). The circular arc surface (23) is arranged close to the rotation position (21).

Citation Information

Patent Citations

  • Detector reagent temporary storage assembly

    CN220549490U