Bovine serum multi-stage filtering device

By using a conical drainage member and an inverse conical structure in the multi-stage filtration device of the bovine serum, the problem of filter membrane blockage is solved, and the filtration efficiency and serum purity are improved.

CN223009960UActive Publication Date: 2025-06-24GLOBAL KANG PHARMACEUTICAL (QINHUANGDAO) CO LTD
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Patent Information

Application Number
CN202422059110.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-23
Publication Date
2025-06-24
Estimated Expiration
2034-08-23

AI Technical Summary

Technical Problem

During use, existing bovine serum filtration devices are prone to clogging of the filter membrane due to the accumulation of particulate matter and impurities in the serum, reducing the filtration efficiency.

Method used

A multi-stage filtration device for bovine serum is designed, using a conical drainage member and a support frame of an inverse conical structure. Through the U-shaped groove of the drainage member and the outlet opening, the serum flows through the edge of the filter screen, gathering impurities in the center to avoid blockage.

Benefits of technology

It effectively improves filtration efficiency, extends the service life of the filter, and ensures high purity and quality of the serum.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of serum multi-stage filtering devices, and provides a bovine serum multi-stage filtering device which comprises a top cover, a liquid inlet pipe is arranged on the top cover, a filtering structure is arranged at one end, far away from the liquid inlet pipe, of the lower end of the top cover, the filtering structure comprises a drainage cylinder and a filtering cylinder, and a liquid outlet pipe is arranged at the tail end of the filtering cylinder of the filtering structure farthest away from the top cover. A supporting framework is arranged in the filter cartridge and is of an inverted cone structure, a drainage piece is arranged in the drainage cartridge and is of a cone structure, a U-shaped groove surrounds the edge of the drainage piece, the U-shaped groove is provided with a plurality of liquid outlets, and the liquid outlets are circumferentially arranged around the U-shaped groove. According to the technical scheme, the problems that in the prior art, due to the fact that a large number of particles and impurities are contained in serum, the impurities can be gradually accumulated on the surface and in pores of a filter membrane, the filter membrane is blocked, and then the filtering efficiency is reduced are solved.
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Description

Technical Field

[0001] The utility model relates to the technical field of serum multi-stage filtration devices, and specifically, to a bovine serum multi-stage filtration device. Background Art

[0002] Bovine serum is an important biological product extracted from bovine blood, mainly used in biomedical research, cell culture, vaccine production, and the preparation of diagnostic reagents. Due to its important role in life science research and biopharmaceutical fields, the quality and purity of bovine serum directly affect the results of experiments and production. Therefore, high requirements are put forward for the extraction and purification process of bovine serum.

[0003] In the extraction and purification process of bovine serum, filtration is a key step, aiming to remove particulate matters, bacteria, and other impurities in the serum to ensure the purity and quality of the final product. Bovine serum filtration devices usually adopt a multi-stage filtration system, gradually reducing the filtration pore size to remove impurities of different sizes step by step, and finally obtaining high-purity serum.

[0004] Although the existing bovine serum filtration devices are relatively mature in design and function, there are still some problems in actual applications. Since the serum contains a large amount of particulate matters and impurities, these impurities will gradually accumulate on the surface and within the pores of the filter membrane, resulting in filter membrane blockage. The blockage phenomenon not only reduces the filtration efficiency but also may cause an increase in the pressure of the filtration device, affecting the stability and effectiveness of the entire filtration process. Summary of the Utility Model

[0005] The utility model provides a bovine serum multi-stage filtration device, which solves the problem in the related art that due to the large amount of particulate matters and impurities in the serum, the impurities will gradually accumulate on the surface and within the pores of the filter membrane, resulting in filter membrane blockage and thus reducing the filtration efficiency.

[0006] The technical solution of the utility model is as follows:

[0007] A bovine serum multi-stage filtering device comprises a top cover, the top cover is provided with a liquid inlet pipe, the lower end of the top cover is detachably connected to a plurality of groups of filter structures at one end away from the liquid inlet pipe, the plurality of groups of filter structures are detachably connected to each other, the plurality of groups of filter structures are linearly arranged along the top cover, the filter structure comprises a drainage tube and a filter tube, the drainage tube is detachably connected to the filter tube, a liquid outlet pipe is provided at the end of the filter tube of a group of filter structures farthest from the top cover, a support frame is provided in the filter tube, different support frames are fixedly connected with filter nets of different apertures, the filter nets of different apertures are arranged in order from large aperture to small aperture, the support frame is in an inverted cone structure, the middle part of the support frame comprises a first tip, the first tip faces the liquid outlet pipe, a drainage piece is provided in the drainage tube, the drainage piece is in a cone structure, the middle part of the drainage piece comprises a second tip, the second tip faces the liquid inlet pipe, the edge of the drainage piece is surrounded by a U-shaped groove, the U-shaped groove is provided with a plurality of liquid outlet openings, and the liquid outlet openings are circumferentially arranged around the U-shaped groove.

[0008] Furthermore, the drainage cylinder and the filter cylinder are each provided with a support plate at one end facing the top cover, the support plate is fixedly connected to the inner wall of the drainage cylinder or the filter cylinder, the support plate extends to the middle of the drainage cylinder or the filter cylinder, the drainage cylinder and the filter cylinder are each provided with a fixing plate at one end away from the top cover, the top cover is also provided with a fixing plate at one end away from the liquid inlet pipe, the fixing plate is fixedly connected to the inner wall of the drainage cylinder or the filter cylinder or the top cover, the fixing plate extends to the middle of the drainage cylinder or the filter cylinder or the top cover, the drainage member and the support frame are clamped and fixed to each other by the fixing plate of the drainage cylinder and the support plate of the filter cylinder, or the fixing plate of the filter cylinder and the support plate of the drainage cylinder, or the fixing plate of the top cover and the support plate of the drainage cylinder.

[0009] Furthermore, except for a group of filter structures closest to the top cover, the drainage cylinders of the remaining groups of filter structures are threadedly connected to the filter cylinders of the previous group of filter structures, the drainage cylinder of the group of filter structures closest to the top cover is threadedly connected to the top cover, the drainage cylinder is threadedly connected to the filter cylinder, and the outer surfaces of the top cover, drainage cylinder and filter cylinder are fixedly connected with handle rods, and the handle rods of the top cover, drainage cylinder and filter cylinder are arranged linearly.

[0010] Furthermore, a cleaning plug is threadedly connected to the tip of the support frame, and the cleaning plug extends from a side of the support frame away from the top cover to a side of the support frame toward the top cover, and extends out of the support frame.

[0011] Furthermore, a stirring structure for stirring the serum on the filter screen is provided on a side of the top cover facing the drainage member, and a driving motor for driving the stirring structure is fixedly connected to a side of the top cover facing away from the drainage member.

[0012] Furthermore, the stirring structure includes a rotating rod and a number of stirring plates. The number of the stirring plates are snap-connected to the rotating rod. One end of the rotating rod is fixedly connected to the rotating shaft of the driving motor. The end of the rotating rod away from the driving motor extends towards the support frame that is farthest from the top cover. The stirring plates are located between the drainage member and the support frame.

[0013] The working principle and beneficial effects of the present utility model are as follows:

[0014] The present utility model uses a drainage member with a conical structure to guide the flow of serum, and makes the second tip of the drainage member face the liquid inlet pipe. Thus, the serum will flow towards the edge of the drainage member. Then, a U-shaped groove is provided at the edge of the drainage member, and a liquid outlet opening is provided in the U-shaped groove. Therefore, the serum drops onto the edge of the filter screen through the liquid outlet opening; then, the filter screen is supported by a support frame with an inverted conical structure, and the first tip of the support frame faces the liquid outlet pipe. Thus, the serum that drops onto the edge of the filter screen flows towards the middle of the support frame, so that the particulate matter or impurities in the serum accumulate towards the middle of the support frame, preventing them from blocking the edge of the filter screen, keeping the edge of the filter screen always having a fast filtering effect, improving the filtering efficiency of the filter screen, and solving the problem in the related art that due to a large amount of particulate matter and impurities in the serum, the impurities will gradually accumulate on the surface and in the pores of the filter membrane, resulting in the blockage of the filter membrane and thus reducing the filtering efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] The following further describes the present utility model in detail with reference to the drawings and specific embodiments.

[0016] Figure 1 is a schematic structural diagram of Embodiment 1;

[0017] Figure 2 is an exploded view of Embodiment 1;

[0018] Figure 3 is an internal cross-sectional view of Embodiment 1;

[0019] Figure 4 is Figure 3 an enlarged view of part A of

[0020] Figure 5 is a schematic structural diagram of Embodiment 2;

[0021] Figure 6 is Figure 5 a cross-sectional view taken along line A-A of

[0022] In the figure: 1. Top cover; 2. Drainage tube; 3. Filter tube; 4. Support skeleton; 5. Drainage part; 6. Handle rod; 7. Liquid outlet pipe; 11. Liquid inlet pipe; 12. Driving motor; 13. Rotating rod; 14. Stirring plate; 21. Support plate; 22. Fixed plate; 41. Filter screen; 42. Cleaning plug; 51. U-shaped groove; 52. Liquid outlet opening; 71. Sealing cover. Detailed implementation manners

[0023] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0024] Embodiment 1

[0025] As Figures 1 to 4 shown, Embodiment 1 proposes a multi-stage filtration device for bovine serum, including a top cover 1. The top cover 1 is provided with a liquid inlet pipe 11. One end of the lower end of the top cover 1 away from the liquid inlet pipe 11 is detachably connected with several groups of filtration structures. The several groups of filtration structures are detachably connected to each other and are linearly arranged along the top cover 1. The filtration structure includes a drainage tube 2 and a filter tube 3. The drainage tube 2 is detachably connected to the filter tube 3. The end of the filter tube 3 of the group of filtration structures farthest from the top cover 1 is provided with a liquid outlet pipe 7. A support skeleton 4 is arranged in the filter tube 3. Different support skeletons 4 are fixedly connected with filter screens 41 with different pore sizes, and the filter screens 41 with different pore sizes are arranged in the order from large pore size to small pore size. The support skeleton 4 is in an inverted cone structure, and the middle of the support skeleton 4 includes a first tip, and the first tip faces the liquid outlet pipe 7. A drainage part 5 is arranged in the drainage tube 2. The drainage part 5 is in a cone structure, and the middle of the drainage part 5 includes a second tip, and the second tip faces the liquid inlet pipe 11. The edge of the drainage part 5 is surrounded by a U-shaped groove 51, and several liquid outlet openings 52 are arranged in the U-shaped groove 51. The liquid outlet openings 52 are arranged circumferentially around the U-shaped groove 51.

[0026] The top cover 1 is used to prevent external contamination from entering the device and provides a stable structural foundation to ensure that liquid flows into the device through the liquid inlet pipe 11. The liquid inlet pipe 11 is used to ensure the smooth entry of liquid into the device. The filtering structure includes multiple independent filtering units, and each filtering structure performs filtering at different levels. Through multi-stage filtering, impurities and particles of different sizes are removed step by step, improving the filtering efficiency and the purity of the final serum. The connections between each group of filtering structures, the drainage cylinder 2, and the filtering cylinder 3 are designed to be detachable, facilitating maintenance, cleaning, and replacement of different filtering components, extending the service life of the device and reducing maintenance costs. The drainage cylinder 2 is used to support the drainage member 5, enabling the drainage member 5 to guide the liquid into the filtering cylinder 3. The drainage member 5 is used to guide the serum to the edge of the filter mesh 41, and then cause the serum to move from the edge of the filter mesh 41 towards the middle thereof. The conical drainage member 5 can achieve the function of moving the serum towards the edge of the filter mesh 41. Through the conical structure, the serum flows towards the edge of the drainage member 5, then enters the U-shaped groove 51, and flows out through the liquid outlet opening 52, dropping to the edge of the filter mesh 41.

[0027] The filtering cylinder 3 is used to support the support framework 4, and then enable the support framework 4 to support the filter mesh 41, so that the filter mesh 41 can stably filter. The support framework 4 is used to support and fix the filter mesh 41, ensuring that the filter mesh 41 remains stable and effective during the filtering process, and avoiding deformation or damage of the filter mesh 41 due to changes in pressure or flow rate; the inverted conical support framework 4 can ensure that the serum flows downward under the action of gravity and at the same time gathers at the center of the filter mesh 41, causing the objects filtered on the filter mesh 41 to gather at the center of the filter mesh 41, so that the edge of the filter mesh 41 maintains a fast filtering effect. Through the cooperation with the drainage member 5, the serum always flows from the edge of the filter mesh 41 towards the middle of the filter mesh 41, so that the serum always first passes through the fast-filtering part for filtering, and then the filter substances gather towards the middle of the filter mesh 41, thereby reducing the clogging phenomenon of the filter mesh 41, extending the service life of the filter mesh 41, and improving the filtering efficiency. Filter meshes 41 with different pore sizes are used for step-by-step filtering, removing impurities of different sizes in sequence from large pore sizes to small pore sizes, improving the filtering accuracy, ensuring the purity and quality of the final serum, and such a setting can prevent the filter mesh 41 from being clogged to a certain extent. Filtering in sequence from large pore sizes to small pore sizes can avoid rapid clogging of a single filter mesh 41 by particles of different diameters, thereby extending the service life of the filter mesh 41. The liquid outlet pipe 7 is used to discharge the filtered serum from the filtering device. A sealing cover 71 can be provided at the end of the liquid outlet pipe 7 to prevent the discharge of serum in special cases and prevent contaminants from entering the device through the liquid outlet pipe 7 when the device is not in use.

[0028] In Embodiment 1, support plates 21 are provided at one ends of the drainage cylinder 2 and the filter cylinder 3 facing the top cover 1. The support plates 21 are fixedly connected to the inner walls of the drainage cylinder 2 or the filter cylinder 3, and the support plates 21 extend towards the middle of the drainage cylinder 2 or the filter cylinder 3. Fixed plates 22 are provided at one ends of the drainage cylinder 2 and the filter cylinder 3 away from the top cover 1, and a fixed plate 22 is also provided at one end of the top cover 1 away from the liquid inlet pipe 11. The fixed plates 22 are fixedly connected to the inner walls of the drainage cylinder 2 or the filter cylinder 3 or the top cover 1, and the fixed plates 22 extend towards the middle of the drainage cylinder 2 or the filter cylinder 3 or the top cover 1. The drainage member 5 and the support skeleton 4 are clamped and fixed to each other through the fixed plate 22 of the drainage cylinder 2 and the support plate 21 of the filter cylinder 3, or the fixed plate 22 of the filter cylinder 3 and the support plate 21 of the drainage cylinder 2, or the fixed plate 22 of the top cover 1 and the support plate 21 of the drainage cylinder 2. The support plate 21 is used to support the drainage member 5 or the support skeleton 4, and cooperate with the fixing member to clamp the drainage member 5 or the support skeleton 4, so that it will not move or shake during use, ensuring its stable operation. And by clamping with the fixing members and support members on different parts, after the drainage cylinder 2 and the filter cylinder 3 or the drainage cylinder 2 and the top cover 1 in the device are disassembled, the drainage member 5 or the support skeleton 4 clamped by them can be quickly disassembled, thus facilitating the cleaning personnel to clean the device, thereby improving the cleaning efficiency and reducing the disassembly and installation time of the device.

[0029] In Embodiment 1, except for the set of filter structures closest to the top cover 1, the drainage cylinders 2 of the remaining sets of filter structures are threadedly connected to the filter cylinders 3 of the previous set of filter structures, and the drainage cylinder 2 of the set of filter structures closest to the top cover 1 is threadedly connected to the top cover 1. The drainage cylinder 2 is threadedly connected to the filter cylinder 3, and handle rods 6 are fixedly connected to the outer surfaces of the top cover 1, the drainage cylinder 2, and the filter cylinder 3. The handle rods 6 of the top cover 1, the drainage cylinder 2, and the filter cylinder 3 are arranged linearly. The threaded connection between the drainage cylinder 2 and the top cover 1, and the drainage cylinder 2 and the filter cylinder 3 is convenient for disassembly and installation, and the connection part can withstand greater tensile force and shear force. The handle rods 6 are used to facilitate the operator to install the drainage cylinder 2 and the filter cylinder 3. At the same time, the handle rods 6 on different parts can also be used to facilitate the operator to check whether the threads of the drainage cylinder 2 and the filter cylinder 3 are tightened by whether the handle rods 6 are aligned, ensuring that the drainage cylinder 2 and the filter cylinder 3 can be stably connected during use.

[0030] In Embodiment 1, a cleaning plug 42 is threadedly connected to the tip of the support skeleton 4. The cleaning plug 42 extends from the side of the support skeleton 4 facing away from the top cover 1 towards the side of the support skeleton 4 facing the top cover 1 and extends out of the support skeleton 4. The cleaning plug 42 is used to facilitate the cleaning personnel to clean the waste accumulated in the middle of the filter net 41. A cleaning opening with the same diameter as the cleaning plug 42 should be provided in the middle of the filter net 41. Then, after the cleaning plug 42 is disassembled, the waste accumulated in the middle of the filter net 41 can fall from the opening, thus achieving the effect of rapid cleaning.

[0031] Embodiment 2

[0032] As Figures 5 to 6 shown, the difference between Embodiment 2 and Embodiment 1 is that a stirring structure for stirring the serum on the filter screen 41 is provided on the side of the top cover 1 facing the drainage member 5, and a driving motor 12 for driving the stirring structure is fixedly connected to the side of the top cover 1 facing away from the drainage member 5.

[0033] In Embodiment 2, the stirring structure includes a rotating rod 13 and a plurality of stirring plates 14. The plurality of stirring plates 14 are snap-connected to the rotating rod 13. One end of the rotating rod 13 is fixedly connected to the rotating shaft of the driving motor 12. The end of the rotating rod 13 far from the driving motor 12 extends towards the support frame 4 farthest from the top cover 1. The stirring plates 14 are located between the drainage member 5 and the support frame 4. The rotating rod 13 connects the driving motor 12 and the stirring plates 14 to transmit the rotational power of the driving motor 12. The stirring plates 14 are used to rotate and stir the serum to maintain the fluidity of the serum, prevent particulate matter from depositing on the filter screen 41, thereby reducing the blockage phenomenon and prolonging the service life of the filter screen 41. The stirring plates 14 are snap-connected to the rotating rod 13, which facilitates the operator to disassemble the stirring plates 14 and further facilitates the operator to disassemble the device. In Embodiment 2, except for the support frame 4 closest to the liquid outlet pipe 7, the cleaning plugs 42 are not provided on the remaining support frames 4. The middle is for the insertion of the rotating rod 13, and the rotating rod 13 can also achieve the same effect as the cleaning plug 42. The diameter of the rotating rod 13 should be the same as the diameter of the cleaning plug 42.

[0034] The above are only the preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A bovine serum multi-stage filtration device, comprising a top cover (1), wherein the top cover (1) is provided with a liquid inlet pipe (11), characterized in that: A plurality of groups of filter structures are detachably connected to one end of the lower end of the top cover (1) away from the liquid inlet pipe (11), and the plurality of groups of filter structures are detachably connected to each other. The plurality of groups of filter structures are linearly arranged along the top cover (1), and the filter structure comprises a drainage cylinder (2) and a filter cylinder (3). The drainage cylinder (2) and the filter cylinder (3) are detachably connected. A liquid outlet pipe (7) is provided at the end of the filter cylinder (3) of the group of filter structures farthest from the top cover (1). A support frame (4) is provided inside the filter cylinder (3), and different filter screens (41) with different apertures are fixedly connected to different support frames (4). Filter screens (41) with different apertures are fixedly connected to the filter screens (41) of different apertures. The nets (41) are arranged in order from large aperture to small aperture, the support frame (4) is in an inverted cone structure, the middle of the support frame (4) includes a first tip, the first tip faces the liquid outlet pipe (7), a drainage piece (5) is provided in the drainage tube (2), the drainage piece (5) is in a cone structure, the middle of the drainage piece (5) includes a second tip, the second tip faces the liquid inlet pipe (11), the edge of the drainage piece (5) is surrounded by a U-shaped groove (51), the U-shaped groove (51) is provided with a plurality of liquid outlet openings (52), and the liquid outlet openings (52) are arranged circumferentially around the U-shaped groove (51).

2. A bovine serum multi-stage filtration device according to claim 1, characterized in that: The drainage cylinder (2) and the filter cylinder (3) are each provided with a support plate (21) at one end facing the top cover (1); the support plate (21) is fixedly connected to the inner wall of the drainage cylinder (2) or the filter cylinder (3); the support plate (21) extends toward the middle of the drainage cylinder (2) or the filter cylinder (3); the drainage cylinder (2) and the filter cylinder (3) are each provided with a fixing plate (22) at one end away from the top cover (1); the top cover (1) is also provided with a fixing plate (22) at one end away from the liquid inlet pipe (11); the fixing plate (22) is connected to the drainage cylinder (2) and the filter cylinder (3) at one end away from the liquid inlet pipe (11); The drainage tube (2) or the filter tube (3) or the inner wall of the top cover (1) is fixedly connected, the fixing plate (22) extends toward the middle of the drainage tube (2) or the filter tube (3) or the top cover (1), and the drainage member (5) and the supporting frame (4) are mutually clamped and fixed by the fixing plate (22) of the drainage tube (2) and the supporting plate (21) of the filter tube (3), or the fixing plate (22) of the filter tube (3) and the supporting plate (21) of the drainage tube (2), or the fixing plate (22) of the top cover (1) and the supporting plate (21) of the drainage tube (2).

3. A bovine serum multi-stage filtration device according to claim 1, characterized in that: Except for a group of filter structures closest to the top cover (1), the drainage tubes (2) of the other groups of filter structures are all threadedly connected to the filter tubes (3) of the previous group of filter structures; the drainage tube (2) of the group of filter structures closest to the top cover (1) is threadedly connected to the top cover (1); the drainage tube (2) is threadedly connected to the filter tube (3); the outer surfaces of the top cover (1), the drainage tube (2) and the filter tube (3) are all fixedly connected with handle bars (6); and the handle bars (6) of the top cover (1), the drainage tube (2) and the filter tube (3) are arranged linearly.

4. The bovine serum multi-stage filtration device according to claim 1, characterized in that: The tip of the support frame (4) is threadedly connected with a cleaning plug (42), and the cleaning plug (42) extends from a side of the support frame (4) away from the top cover (1) to a side of the support frame (4) facing the top cover (1), and extends out of the support frame (4).

5. The bovine serum multi-stage filtration device according to claim 1, characterized in that: A stirring structure for stirring the serum on the filter screen (41) is provided on the side of the top cover (1) facing the drainage member (5), and a driving motor (12) for driving the stirring structure is fixedly connected to the side of the top cover (1) facing away from the drainage member (5).

6. A bovine serum multi-stage filtration device according to claim 5, characterized in that: The stirring structure comprises a rotating rod (13) and a plurality of stirring plates (14); the plurality of stirring plates (14) are clamped with the rotating rod (13); one end of the rotating rod (13) is fixedly connected to the rotating shaft of the driving motor (12); the end of the rotating rod (13) away from the driving motor (12) extends toward the supporting frame (4) farthest from the top cover (1); and the stirring plates (14) are located between the drainage member (5) and the supporting frame (4).