Low-temperature transfer instrument

Abstract

The utility model belongs to the technical field of experimental instruments, and particularly relates to an experimental sample low-temperature transfer instrument. The utility model discloses a low-temperature transfer instrument. The low-temperature transfer instrument comprises a sealing part and a storage part, the storage part comprises a shell and a storage bin; the storage bin is arranged in the shell; the sealing part blocks the opening of the shell; an interlayer is arranged in the storage bin; and the interlayer is filled with a liquid heat-conducting medium. When in use, a sample is placed in the storage bin, heat of the sample is transferred outwards through the heat-conducting medium, so that the sample is gradually cooled at a relatively consistent speed, the condition of sudden temperature drop is avoided, and the conditions of ice crystal and tissue damage or damage or degradation of protein, RNA and DNA molecules are prevented.

Description

Technical Field

[0001] The utility model belongs to the technical field of experimental instruments, and particularly relates to a low-temperature transfer instrument for experimental samples. Background Art

[0002] A biobank is a device for standardizing the collection, processing, and storage of biological macromolecules, cells, tissues, organs, etc. of healthy and diseased organisms. Before storage, biological samples need to be cooled down by a programmed cooling method to make them dormant, and then stored in a liquid nitrogen container or a deep low-temperature refrigerator. For certain specific biological samples, their storage process requires full cold-chain protection and needs to be in a deep low-temperature environment throughout the process to protect their biological activity and avoid damage caused by repeated freezing and thawing. In the existing technology of biological sample storage, biological samples need to be stored in a transfer mechanism, the transfer mechanism is transported to the side of a deep low-temperature storage tank, and then the biological samples are taken out from the transfer mechanism and put into the deep low-temperature storage tank.

[0003] The transfer mechanism currently in use cannot achieve gradient cooling. Instead, when a sample is placed in it, the temperature inside the transfer mechanism will drop suddenly, causing ice crystals, tissue damage, or damage or degradation of protein, RNA, and DNA molecules.

[0004] The utility model aims at the above problems and provides a low-temperature transfer instrument. Content of the Utility Model

[0005] In order to overcome the problems raised in the background art, the utility model provides a low-temperature transfer instrument.

[0006] A low-temperature transfer instrument includes a sealing part and a storage part; the storage part includes a housing and a storage bin; the storage bin is arranged inside the housing; the sealing part plugs the opening of the housing; a sandwich layer is arranged inside the storage bin; and the sandwich layer is filled with a liquid heat-conducting medium.

[0007] Furthermore, a placement rack is arranged inside the storage bin; and at least two placement positions are arranged inside the placement rack.

[0008] Furthermore, at least two placement racks are arranged inside the storage bin; and the placement racks are uniformly arranged along the axial direction of the storage bin inside the storage bin.

[0009] Furthermore, a limiting rack is arranged inside the storage bin; and the placement rack is detachably connected to the limiting rack.

[0010] Furthermore, a handle is arranged at one end of the sealing part away from the storage part; and the handle is rotatably connected to the storage part.

[0011] Furthermore, an avoidance groove is arranged on the sealing part; and the handle is stored inside the avoidance groove.

[0012] Furthermore, feet are provided at one end of the outer shell away from the sealing part.

[0013] Furthermore, a limiting groove is provided at one end of the sealing part away from the storage part; the feet are detachably connected to the limiting groove.

[0014] Furthermore, the outer shell is threadedly connected to the sealing part.

[0015] Furthermore, the storage part further includes a support structure; one end of the support structure is connected to the inner wall of the outer shell, and the other end is connected to the outer wall of the storage bin.

[0016] Advantages of the present utility model: A sandwich layer is provided inside the storage bin, and a liquid heat-conducting medium is placed in the sandwich layer, enabling the heat of the sample to be transferred outward through the heat-conducting medium, allowing the sample to gradually cool down at a relatively consistent speed, eliminating the situation of sudden temperature drop, and preventing the occurrence of ice crystals, tissue damage, or damage or degradation of protein, RNA, and DNA molecules. Description of the Drawings

[0017] Figure 1 It is a perspective view of a low-temperature transfer instrument for implementing the present utility model;

[0018] Figure 2 It is a top view of a low-temperature transfer instrument for implementing the present utility model;

[0019] Figure 3 It is Figure 2 a cross-sectional view taken along the A-A direction of

[0020] Figure 4 It is a perspective view of a sealing part for implementing the present utility model;

[0021] Figure 5 It is a top view of a storage part for implementing the present utility model;

[0022] Figure 6 It is a perspective view of a placement rack for implementing the present utility model;

[0023] In the figure, 1, sealing part; 2, storage part; 3, placement rack; 11, limiting groove; 12, handle; 13, avoidance groove; 21, outer shell; 22, storage bin; 23, support structure; 24, feet; 31, convex block; 221, sandwich layer; 222, limiting frame; 223, sealing plug; 224, injection port. Detailed Embodiments

[0024] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all of the embodiments. The present utility model can also be implemented or applied through other different specific implementation manners. Without conflict, the features in the following embodiments and the embodiments can be combined with each other. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without creative efforts belong to the scope of protection of the present utility model.

[0025] In the description of the present utility model, it should be understood that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "front", "rear", "vertical", "inner", "outer", etc. is based on the orientation or positional relationship shown in the accompanying drawings. It is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation to the present utility model.

[0026] In addition, in the description of the present utility model, the meaning of "a plurality" is two or more, unless otherwise specifically defined.

[0027] As Figures 1-6 shown, a low-temperature transfer instrument includes a sealing part 1 and a storage part 2; the storage part 2 includes a housing 21 and a storage bin 22; the storage bin 22 is arranged inside the housing 21; the sealing part 1 plugs the opening of the housing 21; a sandwich layer 221 is arranged inside the storage bin 22; the sandwich layer 221 is filled with a liquid heat-conducting medium.

[0028] During use, the sample is placed inside the storage bin 22, and the heat of the sample is transferred out through the heat-conducting medium, so that the sample gradually cools down at a relatively consistent speed, eliminating the situation of sudden temperature drop, and preventing the occurrence of ice crystals, tissue damage, or the destruction or degradation of protein, RNA, and DNA molecules.

[0029] Specifically, the housing 21 is threadedly connected to the sealing part 1.

[0030] Furthermore, the storage part 2 further includes a support structure 23; one end of the support structure 23 is connected to the inner wall of the housing 21, and the other end is connected to the outer wall of the storage bin 22. The purpose of the support structure 23 is to limit the distance between the storage bin 22 and the housing 21 and prevent the storage bin 22 from contacting the housing 21.

[0031] In a specific example of the present application, isopropanol is placed inside the sandwich layer 221, and dry ice or liquid nitrogen is placed at the position between the storage bin 22 and the housing 21.

[0032] Further, an injection port 224 and a sealing plug 223 are provided on the storage bin 22. The injection port 224 and the sealing plug 223 are detachably connected, and the sealing plug 223 can selectively block the input port. The injection port 224 communicates with the internal space of the interlayer 221. By opening the sealing plug 223, a liquid medium such as isopropyl alcohol can be supplemented into the interlayer 221 through the injection port 224.

[0033] Specifically, the injection port 224 is located near the opening of the storage bin 22 and on the outer side wall of the storage bin 22. This facilitates the replenishment of the liquid medium into the interlayer 221 while preventing the injection port 224 from obstructing the sample from entering and leaving the storage bin 22.

[0034] When the sealing part 1 completely blocks the outer shell 21, the sealing part 1 also completely blocks the storage bin 22.

[0035] Such as Figure 3 、 6 As shown, a placement rack 3 is provided inside the storage bin 22; at least two placement positions are provided inside the placement rack 3. During use, items such as test tubes and storage boxes containing samples are placed inside the placement positions to prevent them from falling off.

[0036] Specifically, the placement rack 3 is provided with a plurality of placement positions of different sizes to meet the usage requirements.

[0037] In some embodiments of the present application, at least two placement racks 3 are provided inside the storage bin 22; the placement racks 3 are arranged uniformly along the axial direction of the storage bin 22 inside the storage bin 22. The purpose is to increase the storage capacity of the storage bin 22.

[0038] Such as Figure 3 、 5 As shown, a limiting rack 222 is provided inside the storage bin 22; the placement rack 3 is detachably connected to the limiting rack 222. The limiting rack 222 is arranged circumferentially around the axis of the storage bin 22 on the inner wall of the storage bin 22.

[0039] Specifically, at least two layers of limiting racks 222 are provided inside the storage bin 22 to install a plurality of placement racks 3. Each layer of the limiting rack 222 is alternately arranged and does not block each other in the vertical direction to facilitate the entry of the placement rack 3.

[0040] Such as Figure 2 、 4 As shown, a handle 12 is provided at one end of the sealing part 1 away from the storage part 2; the handle 12 is rotatably connected to the storage part 2. The function of the handle 12 is to facilitate lifting the entire instrument during transportation.

[0041] In some illustrative embodiments of the present application, an avoidance groove 13 is provided on the sealing part 1; when the handle 12 is not needed, the handle 12 is received inside the avoidance groove 13.

[0042] Specifically, the thickness of the handle 12 is less than or equal to the depth of the avoidance groove 13. When the handle 12 is received inside the avoidance groove 13, the handle 12 is completely sunk into the inside of the avoidance groove 13.

[0043] Furthermore, auxiliary grooves are provided on the side walls of the avoidance groove 13. The function of the auxiliary grooves is to enable the user to insert a finger into the avoidance groove 13 and contact the handle 12, facilitating the removal of the handle 12 from the inside of the avoidance groove 13.

[0044] In some examples of the present application, as Figures 1-6 shown, feet 24 are provided at one end of the outer shell 21 away from the sealing portion 1.

[0045] Furthermore, a limiting groove 11 is provided at one end of the sealing portion 1 away from the storage portion 2; the feet 24 are detachably connected to the limiting groove 11. When stacking cryogenic transfer instruments, the feet 24 are inserted into the limiting groove 11 of the adjacent sealing portion 1, which can prevent the adjacent cryogenic transfer instruments from being displaced and achieve the purpose of preventing tipping.

[0046] As Figures 1-6 shown, both the sealing portion 1 and the storage portion 2 are circular structures. The storage bin 22 and the outer shell 21 are both circular barrel-shaped structures with openings.

[0047] In the description of this specification, the descriptions with reference to terms such as "one embodiment", "some embodiments", "illustrative embodiments", "examples", "specific examples", "some examples", etc. mean that the specific features, structures, materials or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the present utility model. In this specification, the schematic descriptions of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in a suitable manner in any one or more embodiments or examples.

[0048] The embodiments described in the present application are only a part of the embodiments of the present utility model, rather than all embodiments. Those skilled in the art can easily understand other advantages and effects of the present utility model from the content disclosed in this specification. The present utility model can also be implemented or applied through other different specific embodiments. Without conflict, the following embodiments and the features in the embodiments can be combined with each other. Based on the embodiments in the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts fall within the scope of protection of the present utility model.

Claims

1. A low temperature transfer device, comprising a sealing portion and a storage portion, characterized in that: The storage part comprises an outer shell and a storage bin; the storage bin is arranged inside the outer shell; the sealing part blocks the opening of the outer shell; an interlayer is arranged inside the storage bin; and the interlayer is filled with liquid heat-conducting medium.

2. A low temperature transfer device according to claim 1, characterized in that: A placement rack is provided inside the storage bin; and at least two placement positions are provided inside the placement rack.

3. A low temperature transfer device according to claim 2, characterized in that: At least two placement racks are arranged inside the storage bin; the placement racks are evenly arranged inside the storage bin along the axial direction of the storage bin.

4. A low temperature transfer device according to claim 2, characterized in that: A limiting frame is arranged inside the storage bin; the placing frame is detachably connected to the limiting frame.

5. A low temperature transfer device according to claim 1, characterized in that: A handle is provided at one end of the sealing portion away from the storage portion; the handle is rotatably connected to the storage portion.

6. A low temperature transfer device according to claim 5, characterized in that: The sealing portion is provided with an escape groove; the handle is received in the escape groove.

7. A low temperature transfer device according to claim 1, characterized in that: A supporting foot is provided at one end of the housing away from the sealing portion.

8. A low temperature transfer device according to claim 7, characterized in that: A limiting groove is provided at one end of the sealing portion away from the storage portion; and the supporting foot is detachably connected to the limiting groove.

9. A low temperature transfer device according to claim 1, characterized in that: The housing is threadedly connected to the sealing portion.

10. A low temperature transfer device according to claim 1, characterized in that: The storage part also includes a supporting structure; one end of the supporting structure is connected to the inner wall of the shell, and the other end is connected to the outer wall of the storage bin.

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