Demolding device and embedding machine

Abstract

The utility model belongs to the technical field of medical equipment, and relates to a demolding device and an embedding machine, the demolding device comprises a mold base, an embedding bottom mold and a pressing piece, the mold base is provided with a demolding area, and at least one ejection piece is convexly arranged in the demolding area; the embedding bottom die is provided with an embedding cavity and an avoiding hole, the embedding cavity is used for embedding a tissue sample, and the avoiding hole is located in the periphery of the embedding cavity; the pressing piece is used for pressing the embedding bottom die, so that the embedding bottom die moves in the depth direction of the embedding cavity; when the embedding bottom mold is contained in the demolding area, the bottom of the embedding box faces the embedding cavity and is arranged on the embedding bottom mold and covers the embedding cavity, the ejection piece is in butt joint with the avoiding hole, and when the embedding bottom mold moves in the depth direction of the embedding cavity, the top end of the ejection piece stretches out of the avoiding hole and abuts against the bottom of the embedding box arranged on the embedding bottom mold; the extending part continuously abuts against the bottom of the embedding box along with the increasing length of the extending part, and finally the embedding box and the embedding part embedded with the tissue sample are separated from the embedding bottom die. The demolding efficiency is high, hands are not prone to being hurt, and embedding automation can be achieved easily.

Description

Technical Field

[0001] This application relates to the technical field of medical devices, and particularly to a demolding device and an embedding machine. Background Art

[0002] Pathological diagnosis is the gold standard for clinical disease diagnosis such as disease diagnosis, prognosis judgment, and detection of treatment targets. The general operation process is as follows: During clinical surgery, a doctor obtains a tissue sample from the corresponding position of a patient. After a series of treatments, the tissue sample is finally prepared into a tissue section. A pathologist observes the tissue structure and cell morphology on the tissue section under a microscope to diagnose the disease, classify it, and use it for further detection of treatment targets and prognosis judgment indicators. Among them, the processing procedures of the tissue sample at least include: dehydration, clearing, infiltration with wax, embedding, sectioning, mounting, staining, and coverslipping.

[0003] For example, the embedding process of a tissue sample generally at least includes a hot stage treatment and a cold stage treatment. Among them, the hot stage treatment process refers to embedding the tissue sample into a hot-melt embedding agent such as paraffin. Exemplarily, the hot-melt embedding agent such as paraffin can be first filled into an embedding bottom mold, then the tissue sample is added to the embedding bottom mold, and then the embedding agent is continuously filled into the embedding bottom mold. Then, the bottom of the embedding cassette is pressed onto the embedding bottom mold, so that the embedding agent such as paraffin penetrates into the hollow embedding cassette to embed the tissue sample on the outer bottom wall of the embedding cassette.

[0004] The cold stage treatment process refers to, after the hot stage treatment, freezing and solidifying, sorting, demolding, and wax trimming the wax block with the tissue sample, in preparation for the next sectioning process. Exemplarily, in the embedding process, the process from the cold stage treatment to the microtome generally at least includes the following:

[0005] 1. After the hot stage treatment, it is manually placed on a freezing table for freezing;

[0006] 2. Then it is transferred from the freezing table to a water cooling area for water cooling to accelerate the complete condensation of the wax block and facilitate demolding;

[0007] 3. Manually separate the embedding bottom mold and the wax block;

[0008] 4. Then scrape off the excess wax around the separated wax block and the embedding cassette;

[0009] 5. Arrange the wax blocks neatly in order and then move them to the microtome for sectioning.

[0010] With the continuous development of science and technology, automated equipment such as automated dehydrators, stainers, and coverslipping machines have emerged in succession in clinical practice, making the efficiency of case diagnosis increase by leaps and bounds. However, the efficiency of many processes in pathological tissue sample processing is still low. For example, in the demolding step of cold table processing, manual operation is still required at present. The traditional method is to hold the embedding bottom mold with fingers and use a sharp tool to pry open the gap between the embedding cassette and the embedding bottom mold to loosen the tissue wax block, and finally facilitate the removal of the tissue wax block and the embedding cassette together. Obviously, such a manual demolding operation method is time-consuming and laborious, and it is very easy to injure the operator's hand. Summary of the Utility Model

[0011] The purpose of the embodiment of the present application is to solve the technical problems that the demolding operation in the existing embedding process is time-consuming and laborious and easy to hurt people.

[0012] To solve the above technical problems, the embodiment of the present application provides a demolding device, which adopts the following technical solutions:

[0013] The demolding device includes:

[0014] A mold base, provided with a demolding area; at least one ejector is convexly provided in the demolding area;

[0015] An embedding bottom mold, provided with an embedding cavity and an avoidance hole, the embedding cavity is used for embedding tissue samples, and the avoidance hole is located outside the embedding cavity;

[0016] A pressing member, used to press the embedding bottom mold so that the embedding bottom mold moves along the depth direction of the embedding cavity;

[0017] When the embedding bottom mold is placed in the demolding area, the ejector is docked with the avoidance hole; when the embedding bottom mold moves along the depth direction of the embedding cavity, the top end of the ejector extends out of the avoidance hole and abuts against the bottom of the embedding cassette placed on the embedding bottom mold, so that the embedding cassette together with the wax block is separated from the embedding bottom mold.

[0018] In some embodiments of the present application, opposite sides of the embedding bottom mold protrude away from the embedding cavity to form a support platform for the pressing member to press;

[0019] When a wax block is connected between the embedding bottom mold and the embedding cassette, in the depth direction of the embedding cavity, the top surface of the support platform is higher than the top surface of the embedding cassette placed on the embedding bottom mold, so as to form an avoidance cavity between the pressing member and the embedding cassette.

[0020] In some embodiments of the present application, when the embedding cassette together with the wax block is separated from the embedding bottom mold, the top surface of the support platform moving along the depth direction of the embedding cavity is flush with the top surface of the embedding cassette;

[0021] And / or, in the depth direction of the embedding cavity, the top surface of the support table is higher than the top surface of the embedding box.

[0022] In some embodiments of the present application, on the opening side of the embedding cavity and at a position corresponding to the embedding cavity, the embedding bottom mold is provided with a receiving cavity for placing the embedding box;

[0023] The receiving cavity communicates with the embedding cavity and is larger than the embedding cavity in size.

[0024] In some embodiments of the present application, the avoidance hole is located at the bottom of the receiving cavity.

[0025] In some embodiments of the present application, the avoidance holes correspond to the top members one by one;

[0026] There are 4 avoidance holes and 4 top members, and the central connection line of the 4 avoidance holes forms a quadrilateral;

[0027] And / or, the inner diameter of the avoidance hole is 1 mm to 3 mm larger than that of the top member;

[0028] And / or, the cross-sectional size of the top member is larger than the size of the grid holes at the bottom of the embedding box.

[0029] In some embodiments of the present application, the mold base is convexly provided with a limiting frame, and the limiting frame encloses a limiting cavity in the corresponding demolding area; the limiting cavity is adapted to the embedding bottom mold.

[0030] In some embodiments of the present application, the mold base is provided with a plurality of the limiting cavities, and the limiting cavities are arranged in a row;

[0031] And / or, the mold base is provided with avoidance holes on opposite sides of the limiting frame, and the avoidance holes communicate with the limiting cavity.

[0032] In some embodiments of the present application, the demolding device further includes a manipulator, and the manipulator is used to automatically grasp the pressing member and move the embedding bottom mold by pressing the pressing member;

[0033] And / or, the manipulator is used to grasp the embedding box connected to the wax block after it is separated from the embedding bottom mold.

[0034] To solve the above technical problems, the embodiments of the present application also provide an embedding machine, adopting the following technical solutions: the embedding machine includes a machine body and the above-mentioned demolding device, and the demolding device is arranged on the machine body.

[0035] Compared with the prior art, the demolding device and the embedding machine provided by the embodiments of the present application mainly have the following beneficial effects:

[0036] The demolding device projects at least one ejector in the demolding area of the mold base, and a embedding cavity for embedding tissue samples and an avoidance hole corresponding to the ejector are provided in the embedding bottom mold, and the avoidance hole is located on the periphery of the embedding cavity. When the embedding bottom mold is placed in the demolding area, the ejector is inserted into the avoidance hole and passes through the embedding bottom mold to abut against the bottom of the embedding box placed on the embedding bottom mold. In this way, when the pressing member presses on the embedding bottom mold and makes the embedding bottom mold move along the ejector towards the mold base, the top end of the ejector can continuously push the bottom of the embedding box as the extended part becomes longer and longer, so that the embedding box together with the wax block is separated from the embedding bottom mold. Therefore, by the opposite-direction actions of the pressing member and the ejector on the embedding bottom mold and the embedding box respectively, the pulling and separating action of the embedding bottom mold and the embedding assembly by the hand is imitated, so as to automatically realize the demolding action of the embedding assembly. Overall, the demolding efficiency is high, there is no need for manual separation, and the hand will not be damaged. Description of the Drawings

[0037] In order to more clearly illustrate the solutions in the present application, the drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the drawings in the following description are some embodiments of the present application or the corresponding prior art. For those of ordinary skill in the art, other drawings can be obtained according to these drawings without creative efforts. Among them:

[0038] Figure 1 is a schematic diagram of the working principle of the demolding device in an example of the present application;

[0039] Figure 2 is a three-dimensional structural diagram of a single mold base and an embedding bottom mold assembled in the demolding device in an example of the present application;

[0040] Figure 3 is a three-dimensional structural diagram of a single mold base, an embedding bottom mold and an embedding box assembled in the demolding device in an example of the present application;

[0041] Figure 4 is a three-dimensional structural diagram of a single mold base in the demolding device in an example of the present application;

[0042] Figure 5 is a three-dimensional structural diagram of the embedding bottom mold in the demolding device in an example of the present application;

[0043] Figure 6 is a three-dimensional structural diagram of the cooperation between the embedding bottom mold and the embedding assembly in the demolding device in an example of the present application;

[0044] Figure 7 is Figure 6 a three-dimensional structural diagram of the separation between the embedding assembly and the embedding bottom mold;

[0045] Figure 8It is a schematic three-dimensional structure diagram of an embedding box of an embedding component in an example of this application;

[0046] Figure 9 It is a schematic three-dimensional structure diagram of a plurality of mold bases arranged side by side in a demolding device in an example of this application;

[0047] Figure 10 It is a schematic three-dimensional structure diagram of a plurality of mold bases in a demolding device, each of which is provided with an embedding bottom mold and an embedding component, in an example of this application;

[0048] Figure 11 It is Figure 10 a schematic three-dimensional structure diagram of the demolding areas corresponding to the respective mold bases in the demolding device when in different states;

[0049] Figure 12 It is a schematic three-dimensional structure diagram of a demolding device or an embedding machine in a certain state in an example of this application;

[0050] Figure 13 It is Figure 12 a schematic three-dimensional structure diagram of the demolding device or the embedding machine in another state.

[0051] The reference numerals in the drawings are as follows:

[0052] 1000, embedding machine; 100, demolding device; 200, machine body; 300, embedding component; 310, embedding box; 311, grid hole; 320, embedding part;

[0053] 1, mold base; 11, demolding area; 12, ejector part / ejector pin; 13, limiting frame; 131, limiting cavity; 14, avoidance hole;

[0054] 2, embedding bottom mold; 21, embedding cavity; 22, avoidance hole; 23, support table; 24, avoidance cavity; 25, accommodating cavity;

[0055] 3, pressing part / pressing block; 4, manipulator. Detailed implementation manners

[0056] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those of ordinary skill in the technical field to which this application belongs; the terms used herein in the specification are only for the purpose of describing specific embodiments and are not intended to limit this application. For example, the terms "length", "width", "upper", "lower", "left", "right", "front", "rear", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. indicate the orientation or position based on the orientation or position shown in the drawings, and are only for convenience of description and cannot be construed as a limitation to the technical solution of this application.

[0057] In the description, claims, and the above accompanying drawing descriptions of this application, the terms "comprising" and "having" and any variations thereof are intended to cover non-exclusive inclusion; the terms "first", "second", etc. in the description, claims, or the above accompanying drawings of this application are used to distinguish different objects, rather than to describe a specific order. The meaning of "a plurality" is two or more, unless otherwise specifically defined.

[0058] In the description, claims, and the above accompanying drawing descriptions of this application, when an element is referred to as being "fixed to", "mounted on", "disposed on", or "connected to" another element, it can be directly or indirectly located on that other element. For example, when an element is referred to as being "connected to" another element, it can be directly or indirectly connected to that other element.

[0059] In addition, as used herein, reference to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of this application. The phrase appears in various places in the description and does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment mutually exclusive with other embodiments. Those skilled in the art will explicitly and implicitly understand that the embodiments described herein can be combined with other embodiments.

[0060] An embodiment of this application provides a demolding device 100, which is applicable to separating an embedding assembly 300 composed of an embedding cassette 310 and an embedding piece 320 from an embedding bottom mold 2 to achieve the demolding action of the embedding assembly 300 (specifically, the embedding cassette 310 together with the wax block 320). It should be noted that a tissue sample (not shown in the figure) can be embedded between the embedding bottom mold 2 and the embedding cassette 310 through an embedding agent (see Figure 6 ), and the cured embedding agent and the tissue sample embedded therein are jointly referred to as the embedding piece 320 (see Figure 7 ), specifically, it can be a wax block 320. Among them, during demolding, the wax block 320 is located at the bottom of the embedding cassette 310, and the wax block 320 embedded with the tissue sample is separated from the embedding bottom mold 2 together with the embedding cassette 310 (see Figure 7 ). In addition, the demolding action described herein can refer to the demolding action during the cold table treatment process of the embedding process.

[0061] It should be noted that the embedding agent described herein includes but is not limited to paraffin. For the convenience of description, the embedding piece 320 in this article is described by taking the wax block 320 as an example.

[0062] In the embodiment of this application, as Figure 1As shown, the demolding device 100 includes a mold base 1, an embedding bottom mold 2, and a pressing member 3. The mold base 1 is provided with a demolding area 11, and the demolding area 11 mentioned here refers to the area where demolding operations can be performed. It should be noted that in the demolding area 11, only one embedding assembly 300 can be separated from the embedding bottom mold 2, or multiple embedding assemblies 300 can be separated from the corresponding embedding bottom molds 2. For the convenience of description, hereinafter, the case where a single embedding assembly 300 is separated from the embedding bottom mold 2 will be mainly used as an example for illustration.

[0063] In the embodiments of the present application, as Figure 2 and Figure 4 shown, at least one ejector 12 protrudes in the demolding area 11 of the mold base 1. As Figures 1 to 3 、 Figure 5 and Figure 7 shown, the embedding bottom mold 2 is provided with an embedding cavity 21 and a relief hole 22. Among them, the embedding cavity 21 can be used for embedding tissue samples. Exemplarily, in the hot stage treatment operation, an embedding agent such as paraffin can be injected into the embedding cavity 21 of the embedding bottom mold 2, then the tissue sample is placed in the embedding cavity 21, and then more embedding agent such as paraffin is continuously injected into the embedding cavity 21. After the embedding agent cools and solidifies, the above-mentioned embedding member 320, such as a wax block 320, can be formed in the embedding cavity 21. It can be understood that the size and shape of the wax block 320 respectively match the size and shape of the embedding cavity 21.

[0064] To not affect the wax block 320 in the embedding cavity 21 and facilitate the support and abutment of the ejector 12 against the embedding box 310, as Figure 2 and Figure 7 shown, the relief hole 22 is located outside the embedding cavity 21. Exemplarily, the number of relief holes 22 is the same as that of the ejectors 12 and they correspond one by one.

[0065] In the embodiments of the present application, the pressing member 3 can be used to press the embedding bottom mold 2 so that the embedding bottom mold 2 moves along the depth direction of the embedding cavity 21. Among them, as Figures 1 to 3 shown, when the embedding bottom mold 2 is placed in the demolding area 11, the ejector 12 of the mold base 1 abuts against the relief hole 22. Among them, after the embedding agent between the embedding bottom mold 2 and the embedding box 310 is completely condensed into a wax block 320, and when the embedding bottom mold 2 moves along the depth direction of the embedding cavity 21, the top end of the ejector 12 extends out of the relief hole 22 (see Figure 2 ) and abuts against the bottom of the embedding box 310 placed on the embedding bottom mold 2, so as to continuously abut against the bottom of the embedding box 310 through the top end of the ejector 12, and finally the embedding box 310 together with the wax block 320 (referred to as the above-mentioned embedding assembly 300) can be separated from the embedding bottom mold 2 (see Figure 7 ).

[0066] It can be understood that before the embedding bottom mold 2 moves along the depth direction of the embedding cavity 21, the top end of the top piece 12 can be located in the avoidance hole 22. In this way, during the movement of the embedding bottom mold 2, the top end of the top piece 12 can first be gradually exposed from the avoidance hole 22, and then the part exposed from the avoidance hole 22 becomes longer and longer, thereby increasing the resistance force on the bottom of the embedding box 310; or, before the embedding bottom mold 2 moves along the depth direction of the embedding cavity 21, the top end of the top piece 12 can already extend out of a part of the avoidance hole 22. In this way, during the movement of the embedding bottom mold 2, the extended part of the top end of the top piece 12 will become longer and longer, thereby increasing the resistance force on the bottom of the embedding box 310, and finally separating the embedding box 310 together with the wax block 320 from the embedding bottom mold 2.

[0067] For example, Figures 1 to 3 , Figure 6 As shown, in the initial state, the embedding bottom mold 2 is placed in the demolding area 11 of the mold base 1, and the avoidance hole 22 of the embedding bottom mold 2 is correspondingly plugged into the top piece 12 of the embedding bottom mold 2, so that the embedding bottom mold 2 can move along the axial direction of the top piece 12 (corresponding to the depth direction of the embedding cavity 21); in addition, in order to facilitate better and faster formation of the wax block 320 between the embedding bottom mold 2 and the embedding box 310 and reduce the residual wax, the embedding box 310 is placed on the embedding bottom mold 2, with the bottom facing the embedding cavity 21 and covering the embedding cavity 21, and the wax block 320 is in the embedding cavity 21, between the embedding box 310 and the embedding bottom mold 2, and is fixedly connected to the embedding box 310 and the embedding bottom mold 2 through the solidified embedding agent.

[0068] For example Figure 1 As shown, during the demoulding process, after it is determined that the embedding agent is completely cooled and solidified, the pressing piece 3 can be placed on the embedding bottom mold 2, and the pressing piece 3 can be pressed down with force to make the embedding bottom mold 2 move toward the mold base 1 along the top piece 12 of the mold base 1 (corresponding to the depth direction of the embedding cavity 21). During the sinking and moving process of the embedding bottom mold 2, on the one hand, on the side facing the embedding cavity 21, it can be equivalent to simulating a hand grabbing the embedding bottom mold 2 and moving it away from the embedding component 300. On the other hand, because the top piece 12 is exposed from the embedding bottom mold 2, the top piece 12 can be moved to the side facing away from the embedding component 300. The part of the mold 2 is getting longer and longer, and the ejected ejector 12 can continuously push the embedding box 310 to the side facing away from the embedding cavity 21, which is equivalent to simulating that another hand grasps the embedding box 310 and moves it to the other side facing away from the embedding component 300, that is, the pressing piece 3 and the ejector 12 respectively act in opposite directions on the embedding bottom mold 2 and the embedding box 310, so as to simulate the action of pulling the embedding bottom mold 2 and the embedding component 300 apart by the hand, until the embedding component 300 is separated from the embedding bottom mold 2, and demoulding is completed.

[0069] In summary, compared with the prior art, the demoulding device 100 has at least the following beneficial effects:

[0070] The demolding device 100 projects at least one ejector 12 in the demolding area 11 of the mold base 1, and a embedding cavity 21 for embedding tissue samples and an avoidance hole 22 corresponding to the ejector 12 for insertion are provided on the embedding bottom mold 2, and the avoidance hole 22 is located on the periphery of the embedding cavity 21. When the embedding bottom mold 2 is placed in the demolding area 11, the ejector 12 is inserted into the avoidance hole 22 and passes through the embedding bottom mold 2 to abut against the bottom of the embedding box 310 placed on the embedding bottom mold 2. In this way, when the pressing member 3 is pressed on the embedding bottom mold 2 to move the embedding bottom mold 2 along the ejector 12 towards the mold base 1, the ejector 12 can continuously push the bottom of the embedding box 310, so that the embedding box 310 together with the wax block 320 is separated from the embedding bottom mold 2. Therefore, by the opposite-direction actions of the pressing member 3 and the ejector 12 on the embedding bottom mold 2 and the embedding box 310 respectively, the pulling and separating action of the embedding bottom mold 2 and the embedding assembly 300 by the hand is imitated, so as to automatically realize the demolding action of the embedding assembly 300. Overall, the demolding efficiency is high, there is no need for manual separation, and the hand will not be damaged.

[0071] To enable those skilled in the art to better understand the solution of this application, the following will be combined with the attached Figures 1 to 13 , and the technical solutions in the embodiments of this application will be described clearly and completely.

[0072] In some embodiments of this application, as Figures 1 to 3 shown, to simplify the overall structure and improve the demolding efficiency, the opposite sides of the embedding bottom mold 2 (specifically, the left and right sides of the embedding bottom mold 2) project outwards with a support platform 23 for the pressing member 3 to press. When a wax block 320 is connected between the embedding bottom mold 2 and the embedding box 310, in the depth direction of the embedding cavity 21 (corresponding to the length direction of the ejector 12), the top surface of the support platform 23 is higher than the top surface of the embedding box 310 placed on the embedding bottom mold 2, so as to form an avoidance cavity 24 between the pressing member 3 and the embedding box 310 (see Figure 1 ), so that the pressing member 3 only presses the embedding bottom mold 2 and will not press the embedding bottom mold 2 and the embedding box 310 at the same time, so as to realize the relative movement between the embedding bottom mold 2 and the embedding box 310, thus facilitating the completion of the demolding action as soon as possible.

[0073] Exemplarily, as Figure 2 and Figure 3 shown, two support platforms 23 with gaps are provided on the left side of the embedding bottom mold 2, and two support platforms 23 with gaps are provided on the right side of the embedding bottom mold 2. Among them, the top surfaces of the four support platforms 23 are on the same horizontal plane, and the four support platforms 23 are arranged in a rectangle, and the pressing member 3 is placed on the four support platforms 23 to facilitate ensuring the stability when the pressing member 3 presses the embedding bottom mold 2. Of course, in other specific embodiments, the support platform 23 can also be provided with other numbers and arranged in different shapes.

[0074] Optionally, as Figure 1As shown, when a wax block 320 is connected between the embedding bottom mold 2 and the embedding box 310, the top surface of the supporting platform 23 of the embedding bottom mold 2 is higher than the top surface of the embedding box 310, and there is a height difference h between the two. Among them, in order to improve the demolding efficiency, h can be 3 mm to 7 mm.

[0075] It should be noted that the specific value of h can be specifically determined according to the depth and / or size of the embedding cavity 21 of the embedding bottom mold 2, and no special limitation is made here. Of course, in other embodiments, the range of h can also be determined according to actual needs, not limited to the range of 3 mm to 7 mm.

[0076] In some embodiments of the present application, when the embedding box 310 together with the wax block 320 (abbreviated as the embedding assembly 300) is separated from the embedding bottom mold 2, the top surface of the supporting platform 23 moving along the depth direction of the embedding cavity 21 is flush with the top surface of the embedding box 310.

[0077] Exemplarily, during the process of the pressing member 3 pressing the supporting platform 23 to make the embedding bottom mold 2 sink along the top member 12, when the top surface of the supporting platform 23 is exactly flush with the top surface of the embedding box 310, the top member 12 can push the embedding box 310 to completely separate the embedding assembly 300 from the embedding bottom mold 2. Obviously, taking the top surface of the supporting platform 23 being flush with the top surface of the embedding box 310 as a signal is conducive to quickly judging the completion of demolding, thereby facilitating the improvement of demolding efficiency.

[0078] In some embodiments of the present application, as Figures 2 to 4 shown, in order to make the structure of the demolding device 100 relatively compact and the installation stability of the embedding box 310, the embedding bottom mold 2 is provided with a receiving cavity 25. It should be noted that the embedding cavity 21 has an opening (not shown in the figure) for injecting the embedding agent, and the tissue sample is also placed in the embedding cavity 21 through this opening. Among them, the receiving cavity 25 is located on the opening side of the embedding cavity 21 and at a position corresponding to the embedding cavity 21, and the receiving cavity 25 communicates with the embedding cavity 21. The size of the receiving cavity 25 is larger than the size of the embedding cavity 21, so that a stepped cavity structure can be jointly formed between the receiving cavity 25 and the embedding cavity 21.

[0079] It can be understood that after placing the tissue sample in the embedding cavity 21 and injecting the embedding agent, the bottom of the embedding box 310 can be directly placed in the receiving cavity 25 with the bottom facing the embedding cavity 21. That is to say, the receiving cavity 25 can be used for placing the embedding box 310.

[0080] Exemplarily, the size and shape of the receiving cavity 25 can be respectively adapted to the embedding box 310, so as to limit the embedding box 310 through the receiving cavity 25 and ensure that there is a displacement between the embedding box 310 and the wax block 320 before the embedding agent is completely cooled and solidified.

[0081] Optionally, as Figure 2 、 Figure 5 andFigure 7 As shown, the avoidance hole 22 of the embedding bottom mold 2 is located at the bottom of the accommodating cavity 25, so as to ensure that the avoidance hole 22 is located outside the embedding cavity 21, and the overall structure of the demolding device 100 is more compact.

[0082] In some embodiments of the present application, as Figure 2 , Figure 4 and Figure 5 shown, to simplify the overall structure of the demolding device 100, the avoidance holes 22 of the embedding bottom mold 2 correspond one-to-one with the ejecting members 12 of the mold base 1.

[0083] Optionally, in a specific embodiment, as Figure 4 and Figure 5 shown, there are 4 avoidance holes 22 and 4 ejecting members 12. Among them, the central connection line of the 4 avoidance holes 22 is in a quadrilateral shape, specifically, preferably a rectangle or a square. In this way, while realizing the stable support of the embedding box 310 by the ejecting member 12, when the embedding box 310 is placed in the accommodating cavity 25, there is no need to distinguish the front and back directions of the embedding box 310, which is beneficial to improving the efficiency of the embedding process. Of course, in other specific embodiments, the number of the avoidance holes 22 and the ejecting members 12 can also be 3 or more, which can be determined according to actual needs and will not be specifically limited here.

[0084] And / or, in a specific embodiment, the inner diameter of the avoidance hole 22 of the embedding bottom mold 2 is 1 mm to 3 mm larger than that of the ejecting member 12 of the mold base 1, so as to allow the installation and placement error of the embedding bottom mold 2, which is beneficial to ensuring the movable insertion and smooth movement of the embedding bottom mold 2.

[0085] Exemplarily, the ejecting member 12 can be selected as a ejector pin, and the avoidance hole 22 can be selected as a round hole, that is, the aperture of the avoidance hole 22 is 1 mm to 3 mm larger than the diameter of the ejector pin.

[0086] And / or, in a specific embodiment, the cross-sectional size of the ejecting member 12 is larger than the size of the bottom grid hole 311 of the embedding box 310 (see Figure 1 or Figure 8 ), so as to prevent the ejecting member 12 from penetrating through the grid hole 311 of the embedding box 310 when abutting against the bottom of the embedding box 310.

[0087] Exemplarily, the ejecting member 12 can be selected as a ejector pin, and the grid hole 311 can be selected as a quadrilateral hole. Among them, the diameter of the ejector pin can be 1 mm to 3 mm larger than the gap of the grid hole 311. It should be noted that in this case, the cross-sectional size of the ejecting member 12 does not necessarily have to be larger than the size of the bottom grid hole 311 of the embedding box 310, but it can also ensure that the ejecting member 12 does not pass through the grid hole 311 of the embedding box 310.

[0088] That is to say, the cross-sectional size of the top piece 12 is larger than the size of the bottom grid holes 311 of the embedding cassette 310, which can ensure that the top piece 12 will definitely not penetrate through the grid holes 311 of the embedding cassette 310. However, in other cases, it is also possible to achieve that the top piece 12 does not penetrate through the grid holes 311.

[0089] In some embodiments of the present application, to facilitate the positioning of the embedding bottom mold 2 and ensure the installation stability of the embedding bottom mold 2, as Figures 2 to 4 shown, the mold base 1 is provided with a protruding limiting frame 13. Among them, the limiting frame 13 encloses a limiting cavity 131 in the corresponding demolding area 11, and the limiting cavity 131 is adapted to the embedding bottom mold 2. In other words, within the demolding area 11, the embedding bottom mold 2 can be just placed in the limiting cavity 131 through the restriction of the limiting frame 13, so as to ensure that the embedding bottom mold 2 is not prone to movement after being placed in the limiting cavity 131.

[0090] In some embodiments of the present application, as Figure 9 and Figure 11 shown, to improve the efficiency of the embedding process and the demolding operation, the mold base 1 is provided with a plurality of limiting cavities 131, among which the limiting cavities 131 are arranged in a line. In this way, a plurality of embedding bottom molds 2 and the corresponding embedding assemblies 300 (see Figure 10 ) can also be arranged in a line at intervals, which is conducive to the sequential demolding operation.

[0091] And / or, in some embodiments of the application, after the demolding is completed, to facilitate the removal of the embedding assembly 300 from the embedding bottom mold 2, as Figures 2 to 4 、 Figure 11 shown, the mold base 1 is provided with avoidance holes 14 on opposite sides (specifically, the left and right sides) of the limiting frame 13, among which the avoidance holes 14 communicate with the limiting cavities 131. In this way, the clamping jaws or hands can be inserted into the avoidance holes 14 to the limiting cavities 131 to clamp or pick up the embedding assembly 300.

[0092] In some embodiments of the application, as Figure 1 、 Figure 12 or Figure 13 shown, the demolding device 100 further includes a manipulator 4, among which the manipulator 4 can be used to automatically grasp the pressing piece 3 and move the pressing piece 3 to press the embedding bottom mold 2. And / or, after separating from the embedding bottom mold 2, the manipulator 4 can grasp and transport the embedding cassette 310 together with the wax block 320 (abbreviated as the embedding assembly 300) to the next process (such as the wax trimming process).

[0093] Exemplarily, the pressing piece 3 can be selected as a pressing block, and the manipulator 4 can grasp both the pressing piece 3 and the demolded embedding assembly 300. For example, as Figure 12 and Figure 13As shown, the briquetting block can be automatically grasped by the manipulator 4, transported and placed on the carrier 23 of the embedding bottom mold 2, and a downward pressure is applied to the briquetting block to achieve automatic pressing. When the top surface of the carrier 23 is flush with the top surface of the embedding box 310, the briquetting block can be first removed by the manipulator 4, and then the clamping jaw of the manipulator 4 passes through the avoidance hole 14 and extends into the limiting cavity 131 to clamp the demolded embedding assembly 300, and the clamped embedding assembly 300 is transferred to a predetermined position.

[0094] Based on the above-mentioned demolding device 100, as Figure 12 and Figure 13 shown, an embodiment of the present application further provides an embedding machine 1000, which includes a machine body 200 and the above-mentioned demolding device 100, wherein the demolding device 100 is arranged on the machine body 200.

[0095] Exemplarily, the demolding area 11 of the mold base 1 can be located in the water-cooling area (not shown in the figure) of the cold table treatment, and a refrigeration structure (not shown in the figure) is provided in the demolding area 11. Specifically, the refrigeration structure can be a refrigeration compressor, and the refrigeration compressor can be communicated with the demolding area 11 through a pipeline; and / or, the demolding area 11 is filled with water for water cooling. Of course, in other embodiments, the refrigeration structure can also adopt other existing or newly created structures, which will not be elaborated here.

[0096] In summary, compared with the prior art, the embedding machine 1000 has at least the following beneficial effects: By adopting the above-mentioned demolding device 100, the demolding efficiency of the embedding machine 1000 is greatly improved, and the hands of the operator are not easily injured, which is beneficial to improving the efficiency and safety of the embedding operation, and facilitating the automation and standardization of the embedding process.

[0097] The above are only the preferred embodiments of the present application and are not intended to limit the present application. For those skilled in the art, various changes and modifications can be made to the present application. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included within the scope of the claims of the present application.

Claims

1. A demoulding device, characterized in that: The demoulding device comprises: The mold base is provided with a demoulding area; at least one ejector is convexly provided in the demoulding area; An embedding bottom mold is provided with an embedding cavity and an avoidance hole, wherein the embedding cavity is used for embedding tissue samples, and the avoidance hole is located at the periphery of the embedding cavity; A pressing piece, used for pressing the embedding bottom mold to move the embedding bottom mold along the depth direction of the embedding cavity; When the embedding bottom mold is accommodated in the demolding area, the top piece is butted against the avoidance hole; when the embedding bottom mold moves along the depth direction of the embedding cavity, the top end of the top piece extends out of the avoidance hole and abuts against the bottom of the embedding box placed on the embedding bottom mold, so that the embedding box together with the wax block is separated from the embedding bottom mold.

2. The demoulding device according to claim 1, characterized in that: Two opposite sides of the embedding bottom mold are provided with support platforms protruding in a direction away from the embedding cavity for the pressing piece to be pressed; When a wax block is connected between the embedding bottom mold and the embedding box, in the depth direction of the embedding cavity, the top surface of the support is higher than the top surface of the embedding box placed on the embedding bottom mold to form an avoidance cavity between the pressing piece and the embedding box.

3. The demoulding device according to claim 2, characterized in that: When the embedding box together with the wax block is separated from the embedding bottom mold, the top surface of the support table moving along the depth direction of the embedding cavity is flush with the top surface of the embedding box; And / or, in the depth direction of the embedding cavity, the top surface of the support is higher than the top surface of the embedding box.

4. The demoulding device according to claim 1, characterized in that: The embedding bottom mold is provided with a receiving cavity for placing the embedding box at the opening side of the embedding cavity and at a position corresponding to the embedding cavity; The accommodating cavity is communicated with the embedding cavity and has a size larger than that of the embedding cavity.

5. The demoulding device according to claim 4, characterized in that: The avoidance hole is located at the bottom of the accommodating cavity.

6. The demoulding device according to claim 5, characterized in that: The avoidance holes correspond to the top pieces one by one; The avoidance holes and the top member are each provided with four, and the center line connecting the four avoidance holes is a quadrilateral; And / or, the inner diameter of the avoidance hole is 1 mm to 3 mm larger than that of the top piece; And / or, the cross-sectional size of the top member is larger than the size of the grid holes at the bottom of the embedding cassette.

7. The demoulding device according to claim 1, characterized in that: The mold base is convexly provided with a limiting frame, and the limiting frame encloses a limiting cavity in the corresponding demoulding area; the limiting cavity is adapted to the embedded bottom mold.

8. The demoulding device according to claim 7, characterized in that: The mold base is provided with a plurality of the limiting cavities, and the limiting cavities are arranged in a line; And / or, the mold base is provided with avoidance holes on two opposite sides of the limiting frame, and the avoidance holes are communicated with the limiting cavity.

9. The demoulding device according to any one of claims 1 to 8, characterized in that: The demoulding device also includes a manipulator, which is used to automatically grab the pressing piece and make the pressing piece press the embedded bottom mold to move; And / or, the manipulator is used to grab the embedding cassette together with the wax block after being separated from the embedding bottom mold.

10. An embedding machine, characterized in that: The embedding machine comprises: Machine body; The demoulding device according to any one of claims 1 to 9, wherein the demoulding device is arranged on the machine body.

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