Reagent diluting device, reagent barrel and sample analyzer

Abstract

The utility model discloses a reagent diluting device, a reagent barrel and a sample analyzer, the reagent diluting device comprises a bearing assembly and a suction tube mechanism, the bearing assembly is provided with a reagent placing position for placing the reagent barrel, the side wall of the reagent barrel is provided with a groove, and the reagent placing position is provided with a bulge. The suction tube mechanism comprises a suction tube, the suction tube is located above the reagent placement position and is slidably connected with the bearing assembly in the vertical direction, the suction tube can extend into the reagent barrel located at the reagent placement position when descending in the vertical direction, and the suction tube can be pulled out of the reagent barrel located at the reagent placement position when ascending in the vertical direction. The protrusion and the groove have a matched state and a non-matched state, in the matched state, the projection of the straw on the plane perpendicular to the vertical direction is located within the range of the projection of the barrel opening part on the plane perpendicular to the vertical direction, and in the non-matched state, the projection of the straw on the plane perpendicular to the vertical direction is located within the range of the projection of the barrel opening part. The projection of the suction pipe on the plane perpendicular to the vertical direction and the projection of the barrel opening part on the plane perpendicular to the vertical direction are staggered.

Description

Technical Field

[0001] The utility model relates to the field of medical equipment, in particular to a reagent dilution device, a reagent barrel and a sample analyzer. Background Art

[0002] The reagents required in the sample analysis process are generally stored in a reagent barrel in a concentrated form. When the reagents are needed, the reagent barrel containing the reagents is placed in a reagent dilution device for dilution.

[0003] The sizes and structures of reagent barrels from different manufacturers may be similar. Operators may mix similar reagent barrels. If they are mixed, it will lead to contamination of reagents and pipetting pipelines, and cause false analysis results in sample analysis. Utility Model Content

[0004] In view of this, the utility model proposes a reagent dilution device, a reagent barrel and a sample analyzer.

[0005] The reagent dilution device provided in the first aspect of the utility model comprises:

[0006] A carrying component having a reagent placement position, the reagent placement position is used to place a reagent barrel, the side wall of the reagent barrel is provided with a groove, and the carrying component is provided with a protrusion at the reagent placement position; and

[0007] A pipette mechanism, comprising a pipette, the pipette being located above the reagent placement position and being slidably connected to the bearing assembly in the vertical direction, the pipette being able to extend into the reagent barrel at the reagent placement position when descending in the vertical direction, and being able to be pulled out of the reagent barrel at the reagent placement position when ascending in the vertical direction;

[0008] The protrusion and the groove have a mating state and a non-mating state;

[0009] Wherein, in the matched state, the projection of the suction tube on the plane perpendicular to the vertical direction is located within the range of the projection of the barrel mouth of the reagent barrel on the plane perpendicular to the vertical direction, so that when the suction tube is lowered, the suction tube can extend from the barrel mouth into the reagent barrel;

[0010] In the non-matching state, the projection of the straw on a plane perpendicular to the vertical direction and the projection of the barrel mouth on a plane perpendicular to the vertical direction are offset.

[0011] The reagent barrel provided in the second aspect of the utility model comprises:

[0012] A barrel body, comprising a top wall, a bottom wall and a surrounding wall, the surrounding wall being connected to the top wall and the bottom wall, and the surrounding wall, the top wall and the bottom wall jointly enclosing a receiving cavity for receiving a reagent; and

[0013] A barrel opening part, provided with an opening connected to the top wall and communicating with the receiving cavity;

[0014] Wherein, a groove and an electronic tag are provided on the surrounding wall of the barrel body, and the electronic tag is at least used for storing information of the reagent in the reagent barrel.

[0015] The reagent barrel proposed in the third aspect of the present utility model comprises:

[0016] A barrel body, comprising a top wall, a bottom wall and a surrounding wall, the surrounding wall being connected to the top wall and the bottom wall, and the surrounding wall, the top wall and the bottom wall jointly enclosing a receiving cavity for receiving a reagent, the surrounding wall comprising opposite first side walls and second side walls, and third side walls and fourth side walls located between the first side walls and the second side walls; and

[0017] A barrel opening part, provided with an opening connected to the top wall and communicating with the receiving cavity, and the distance between the barrel opening part and the first side wall in the horizontal direction is less than the distance between the barrel opening part and the second side wall;

[0018] Wherein, a groove is provided on the first side wall.

[0019] The sample analyzer proposed in the fourth aspect of the present utility model comprises:

[0020] A sample dispensing device, comprising a sample needle and a sample needle driving mechanism, the sample needle driving mechanism being used to drive the sample needle to suck a sample from a sample container and dispense the sample into a reaction container;

[0021] A reagent dispensing device, comprising a reagent needle and a reagent needle driving mechanism, the reagent needle driving mechanism being used to drive the reagent needle to suck a reagent from a reagent container and dispense the reagent into a reaction container;

[0022] A sample detection device, the sample detection device being used to detect a reaction solution made of the sample and the reagent in the reaction container;

[0023] A cleaning device, the cleaning device being used to clean the sample needle and / or the reagent needle; and

[0024] The above-mentioned reagent dilution device;

[0025] Wherein, the reagent dilution device has at least one of the following uses:

[0026] Supply a reagent to the reagent dispensing device for injecting into the reaction vessel to react with the sample;

[0027] Supply a reagent for cleaning the sample needle and / or the reagent needle to the cleaning device.

[0028] The sample analyzer proposed in the fifth aspect of the present utility model includes:

[0029] A sample dispensing device for sucking a sample from a sample container and dispensing the sample into a reaction vessel;

[0030] A reagent dispensing device for sucking a reagent from a reagent container and dispensing the reagent into a reaction vessel, the reagent including a magnetic bead reagent;

[0031] A sample detection device for detecting a reaction solution made of the sample and the reagent in the reaction vessel;

[0032] A magnetic bead cleaning and separating device for cleaning out free substances in the reaction solution; and

[0033] The above-mentioned reagent dilution device;

[0034] Wherein, the reagent dilution device is used to supply the required reagent to the magnetic bead cleaning and separating device.

[0035] As can be seen from the above technical solutions, in the reagent dilution device proposed in the first aspect of the present utility model, a protrusion is provided at the reagent placement position, and the protrusion is used to cooperate with a groove provided on the side wall of the reagent barrel. When a reagent barrel without a groove is placed in the reagent placement position, due to the blocking effect of the protrusion, the reagent barrel cannot be placed in place, and the barrel mouth of the reagent barrel is offset from the pipette in the vertical direction. When the pipette slides downward in the vertical direction, it cannot extend into the interior of the reagent barrel, so reagent misaspiration will not occur, and the situation of reagent and liquid suction pipeline contamination will not occur. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the following will briefly introduce the drawings required for the description of the embodiments. Obviously, the following drawings are some embodiments of the present utility model. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained as these drawings.

[0037] Figure 1a It is a block diagram of a sample analyzer proposed in an embodiment of the present utility model;

[0038] Figure 1b It is a block diagram of a sample analyzer proposed in another embodiment of the present utility model;

[0039] Figure 2 FIG. Figure 2 is a schematic structural diagram of a reagent dilution device and a reagent barrel according to an embodiment of the present invention;

[0040] Figure 3 FIG. is a schematic structural diagram of a reagent barrel according to an embodiment of the present invention;

[0041] Figure 4a FIG. Figure 4a is a schematic connection diagram of a liquid quantitative delivery device, a first pipeline, a second pipeline, a third pipeline, a diluent providing device, and a pipette according to an embodiment of the present invention;

[0042] Figure 4b FIG. is a schematic connection diagram of a liquid quantitative delivery device, a first pipeline, a second pipeline, a third pipeline, a fourth pipeline, a diluent providing device, a mixing container, and a pipette according to an embodiment of the present invention;

[0043] Figure 5 FIG. Figure 5 is a schematic diagram of the cooperation between a protrusion and a groove according to an embodiment of the present invention. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0044] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are some, but not all, of the embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0045] As Figure 1a shown, an embodiment of the present invention provides a sample analyzer 100, and the provided sample analyzer 100 includes a sample dispensing device 10, a reagent dispensing device 20, a sample detection device 30, a cleaning device 40, and a reagent dilution device 50.

[0046] The sample dispensing device 10 is configured to aspirate a sample from a sample container and dispense the sample into a reaction container. In some embodiments, the sample dispensing device 10 includes a sample needle and a sample needle driving mechanism, and the sample needle driving mechanism is configured to drive the sample needle to aspirate a sample from the sample container and dispense the sample into the reaction container. In some embodiments, the sample needle driving mechanism includes a two-dimensional or three-dimensional driving mechanism, and the two-dimensional or three-dimensional driving mechanism drives the sample needle to perform two-dimensional or three-dimensional movement in space.

[0047] The reagent dispensing device 20 is used to aspirate reagents from reagent containers and dispense the reagents into reaction containers. In some embodiments, the reagent dispensing device 20 includes a reagent needle and a reagent needle driving mechanism. The reagent needle driving mechanism is used to drive the reagent needle to aspirate reagents from reagent containers and dispense the reagents into reaction containers. In some embodiments, the reagent needle driving mechanism includes a two-dimensional or three-dimensional driving mechanism, and the two-dimensional or three-dimensional driving mechanism drives the reagent needle to perform two-dimensional or three-dimensional movements in space.

[0048] The sample detection device 30 is used to detect the reaction solution made of samples and reagents in the reaction container. In some embodiments, the sample detection device 30 includes a photometric component. The photometric component is used to perform photometric measurement on the incubated reaction solution to obtain reaction data of the sample. For example, the photometric component detects the luminescence intensity of the reaction solution to be measured, and calculates the concentration of the component to be measured in the sample through a calibration curve, etc.

[0049] The cleaning device 40 is used to clean the sample needle and / or the reagent needle.

[0050] The reagent dilution device 50 is used to provide reagents for injecting into the reaction container to react with the sample to the reagent dispensing device 20. For example, in one embodiment, the reagent dilution device 50 is used to provide a diluent or a magnetic bead reagent for injecting into the reaction container to react with the sample to the reagent dispensing device 20.

[0051] It should be noted that the reagent dilution device 50 is not limited to being set to provide reagents for injecting into the reaction container to react with the sample to the reagent dispensing device 20. For example, in some other embodiments, the reagent dilution device 50 is used to provide reagents for cleaning the sample needle and / or the reagent needle to the cleaning device 40.

[0052] As Figure 1b shown, an embodiment of the present utility model further provides a sample analyzer 100. The sample analyzer 100 includes a sample dispensing device 10, a reagent dispensing device 20, a sample detection device 30, a magnetic bead cleaning and separation device 60, and a reagent dilution device 50. The sample dispensing device 10 is used to aspirate samples from sample containers and dispense the samples into reaction containers. The reagent dispensing device 20 is used to aspirate reagents from reagent containers and dispense the reagents into reaction containers, and the reagents include magnetic bead reagents. The sample detection device 30 is used to detect the reaction solution made of samples and reagents in the reaction container. The magnetic bead cleaning and separation device 60 is used to wash out the free substances in the reaction solution. The reagent dilution device 50 is used to provide the required reagents to the magnetic bead cleaning and separation device 60.

[0053] As Figures 1a to 3As shown, in some embodiments, the reagent diluting device 50 includes a carrying component 51 and a pipette mechanism 52, the carrying component 51 has a reagent placement position E, the reagent placement position E is used to place the reagent barrel 200, the side wall of the reagent barrel 200 is provided with a groove 210, and the carrying component 51 is provided with a protrusion 53 at the reagent placement position E. The pipette mechanism 52 includes a pipette 521, the pipette 521 is located above the reagent placement position E and is slidably connected to the carrying component 51 in the vertical direction, the pipette 521 can be extended into the reagent barrel 200 located at the reagent placement position E when it descends in the vertical direction, and can be pulled out from the reagent barrel 200 located at the reagent placement position E when it rises in the vertical direction. The protrusion 53 and the groove 210 have a mating state and a non-mating state, wherein, in the mating state, the projection of the straw 521 on the plane perpendicular to the vertical direction is located within the range of the projection of the barrel mouth 220 on the plane perpendicular to the vertical direction, so that when the lifting drive assembly drives the straw 521 to descend, the straw 521 can extend from the barrel mouth 220 into the reagent barrel 200, and in the non-mating state, the projection of the straw 521 on the plane perpendicular to the vertical direction and the projection of the barrel mouth 220 on the plane perpendicular to the vertical direction are staggered.

[0054] The “above”, “vertical direction”, “rising” and “falling” are for the state of the reagent diluting device 50 in normal use. The “matching state” means that when the reagent barrel 200 is placed in the reagent placement position E, the protrusion 53 of the reagent placement position E is embedded in the groove 210 of the reagent barrel 200. The “non-matching state” means that the protrusion 53 of the reagent placement position E cannot be embedded in the groove 210 of the reagent barrel 200. It is understandable that the existing reagent barrel 200 is not provided with the groove 210 of the reagent barrel 200 of the present embodiment. When it is placed in the supporting assembly 51 of the present embodiment, it cannot be put into place due to the blocking effect of the protrusion 53, which is equivalent to the above-mentioned non-matching state. At this time, the projection of the suction tube 521 on the plane perpendicular to the vertical direction and the projection of the barrel mouth 220 on the plane perpendicular to the vertical direction are staggered, that is, the suction tube 521 cannot be extended into the reagent barrel 200 from the barrel mouth 220 when it descends, so there will be no accidental aspiration of the reagent, resulting in contamination of the reagent and the liquid pipetting pipeline.

[0055] In the reagent dilution device 50 proposed in this embodiment, a protrusion 53 is provided at the reagent placement position E. The protrusion 53 is used to cooperate with the groove 210 provided on the side wall of the reagent barrel 200. When the reagent barrel 200 without the groove 210 is placed in the reagent placement position E, due to the blocking effect of the protrusion 53, the reagent barrel 200 cannot be placed in place, and the barrel mouth 220 of the reagent barrel 200 is offset from the pipette 521 in the vertical direction. When the pipette 521 slides downward in the vertical direction, it cannot extend into the interior of the reagent barrel 200, so reagent aspiration errors will not occur, and the reagent and the liquid suction pipeline will not be contaminated.

[0056] In some embodiments, the pipette mechanism 52 further includes a lifting drive assembly (not shown in the figure). The lifting drive assembly is installed on the carrier assembly 51 and is connected to the pipette 521. The lifting drive assembly is used to drive the pipette 521 to rise or fall in the vertical direction. Of course, it is not limited to the above implementation manner. For example, in some other embodiments, the pipette mechanism 52 may not include a lifting drive assembly, and the lifting of the pipette 521 can be achieved by manual driving.

[0057] As Figure 2 shown, in some embodiments, the carrier assembly 51 includes a bottom plate 511 and a side plate assembly 512. The side plate assembly 512 is connected to the bottom plate 511. The side plate assembly 512 and the bottom plate 511 jointly enclose the reagent placement position E, and the protrusion 53 is connected to at least the side plate assembly 512.

[0058] As Figure 2 shown, in some embodiments, the protrusion 53 is connected to the side plate assembly 512 and the bottom plate 511. Of course, it is also possible that the protrusion 53 is only connected to the side plate assembly 512.

[0059] As Figure 2 shown, in some embodiments, the side plate assembly 512 includes a first side plate 5121, a second side plate 5122, and a third side plate 5123. The first side plate 5121 is connected to the bottom plate 511. The second side plate 5122 is connected to the bottom plate 511. The second side plate 5122 includes a first end and a second end. The first end of the second side plate 5122 is connected to the first side plate 5121. The third side plate 5123 is connected to the bottom plate 511 and is spaced from the second side plate 5122. The third side plate 5123 includes a first end and a second end. The first end of the third side plate 5123 is connected to the first side plate 5121. Among them, the bottom plate 511, the first side plate 5121, the second side plate 5122, and the third side plate 5123 jointly enclose the reagent placement position E. The second end of the second side plate 5122 and the second end of the third side plate 5123 form an inlet F for the reagent barrel 200 to enter the reagent placement position E, and the protrusion 53 is connected to the first side plate 5121.

[0060] In this embodiment, the second side plate 5122 and the third side plate 5123 can play a limiting role. When the width of the reagent barrel 200 of other manufacturers is greater than the distance between the second side plate 5122 and the third side plate 5123, the reagent placement position E cannot be entered from the inlet F, so accidental aspiration of the reagent will not occur, resulting in contamination of the reagent and the pipetting pipeline.

[0061] It should be noted that the protrusion 53 is not limited to being connected to the first side plate 5121. For example, in some other embodiments, the protrusion 53 is connected to the second side plate 5122, or the protrusion 53 is connected to the third side plate 5123, which can be determined according to actual design requirements.

[0062] like Figure 2 As shown, in some embodiments, the bearing assembly 51 further includes a stopper 513, which is connected to the first side plate 5121 and spaced apart from the bottom plate 511. A slot G matching the shape of the barrel mouth 220 is provided on the side of the stopper 513 facing away from the first side plate 5121. In the mating state, the barrel mouth 220 is embedded in the slot G.

[0063] In this embodiment, the limiter 513 can play a limiting role. When the height of the barrel body of the reagent barrel 200 of other manufacturers is greater than the height of the limiter 513, the barrel mouth 220 of the reagent barrel 200 cannot be embedded in the slot G of the limiter 513. At this time, due to the blocking effect of the limiter 513, the barrel mouth 220 and the suction tube 521 are offset, and the suction tube 521 will not enter the reagent barrel 200 when it descends, so the reagent will not be accidentally aspirated, resulting in contamination of the reagent and the liquid aspiration pipeline.

[0064] It should be noted that, looking at all the above embodiments, the protrusion 53 limits the reagent barrel 200 in the first direction of the reagent barrel 200, the second side plate 5122 and the third side plate 5123 limit the reagent barrel 200 in the second direction of the reagent barrel 200, one of the first direction and the second direction is the length direction, and the other is the width direction, and the limiter 513 limits the reagent barrel 200 in the height direction of the reagent barrel 200. That is, the bearing assembly 51 proposed in the embodiment of the utility model can limit the reagent barrel 200 in the three directions of length, width and height, which can effectively prevent the operator from placing the wrong reagent barrel 200 into the reagent placement position E, thereby effectively preventing the reagent from being mistakenly aspirated, resulting in contamination of the reagent and the liquid pipette.

[0065] Although the carrier component 51 proposed in the above embodiments can effectively prevent operators from placing the wrong reagent barrel 200 in the reagent placement position E, it cannot avoid the occurrence of wrong reagent barrels 200 during the actual detection process. However, the dimensions of the reagent barrel 200 in the three directions of length, width, and height can match the carrier component 51 proposed in the above embodiments. To solve the above problems, in some embodiments, such as Figure 2 and Figure 3 shown, the reagent dilution device 50 further includes a reading device 54. The reading device 54 is connected to the first side plate 5121. The reading device 54 is used to read the electronic tag 230 provided on the reagent barrel 200. The electronic tag 230 is at least used to store information about the reagent in the reagent barrel 200. In this embodiment, when there is no electronic tag 230 on the reagent barrel 200 or the information of the reagent stored in the electronic tag 230 does not match, even if the reagent barrel 200 can be placed in the reagent placement position E, the operator can still determine whether the reagent barrel 200 is misloaded according to the information read by the reading device 54, further ensuring that the wrong reagent barrel 200 will not be placed in the reagent placement position E. The electronic tag 230 can be, but is not limited to, an RFID (Radio Frequency Identification) tag.

[0066] As Figure 4a shown, in some embodiments, the reagent dilution device 50 further includes a liquid quantitative delivery device 55, a first pipeline 56, a second pipeline 57, and a third pipeline 58. The liquid quantitative delivery device 55 has a first inlet 551, a second inlet 552, and an outlet 553. One end of the first pipeline 56 is connected to the first inlet 551 of the liquid quantitative delivery device 55, and the other end of the first pipeline 56 is used to connect to the diluent supply device 300. The second pipeline 57 connects the pipette 521 and the second inlet 552 of the liquid quantitative delivery device 55. The third pipeline 58 is connected to the outlet 553 of the liquid quantitative delivery device 55. The liquid quantitative delivery device 55 is used to input the diluent and the reagent into the third pipeline 58 for mixing according to a preset ratio. The liquid quantitative delivery device 55 can be, but is not limited to, a metering valve. In this embodiment, the diluent and the reagent are mixed in the third pipeline 58, and there is no need to additionally provide a mixing tank, which has the effects of simplifying the mechanism and reducing costs.

[0067] Of course, it is not limited to the above embodiments. For example, in some other embodiments, such as Figure 4bAs shown, the reagent dilution device 50 further includes a liquid metering and conveying device 55, a first pipeline 56, a second pipeline 57, a third pipeline 58, a fourth pipeline 59, and a mixing container R. The liquid metering and conveying device 55 has a first chamber 554, a second chamber 555, a first inlet 551, a second inlet 552, a first outlet 556, and a second outlet 557. The first inlet 551 and the first outlet 556 are communicated with the first chamber 554, and the second inlet 552 and the second outlet 557 are communicated with the second chamber 555. One end of the first pipeline 56 is connected to the first inlet 551 of the liquid metering and conveying device 55, and the other end of the first pipeline 56 is used to be connected to a diluent providing device. The second pipeline 57 connects the pipette 521 and the second inlet 552 of the liquid metering and conveying device 55. The third pipeline 58 connects the mixing container R and the first outlet 556 of the liquid metering and conveying device 55. The fourth pipeline 59 connects the mixing container R and the second outlet 557 of the liquid metering and conveying device 55. The liquid metering and conveying device 55 is used to input the diluent and the reagent into the mixing container R for mixing according to a preset ratio.

[0068] It should be noted that in the above embodiment, the reagent dilution device 50 is a part of the sample analyzer 100. In some other embodiments, the reagent dilution device 50 can also be a separately provided module and not a part of the sample analyzer 100, which can be determined according to actual design requirements.

[0069] As Figure 2 and Figure 3 shown, in some embodiments, the reagent barrel 200 includes a barrel body 240 and a barrel mouth part 220. The barrel body 240 includes a top wall 2401, a bottom wall 2402, and a surrounding wall 2403. The surrounding wall 2403 is connected to the top wall 2401 and the bottom wall 2402. The surrounding wall 2403, the top wall 2401, and the bottom wall 2402 jointly enclose an accommodation cavity for accommodating the reagent. The barrel mouth part 220 is provided with an opening 2201 connected to the top wall 2401 and communicated with the accommodation cavity. Among them, the surrounding wall 2403 of the barrel body 240 is provided with a groove 210 and an electronic tag 230. The electronic tag 230 is at least used to store information about the reagent in the reagent barrel 200. The groove 210 is used to cooperate with a protrusion 53 provided at the reagent placement position E of the reagent dilution device 50.

[0070] The reagent barrel 200 proposed in this embodiment forms an anti-misoperation function by providing a groove 210 on the peripheral wall 2403 of the barrel body 240. The groove 210 can cooperate with the protrusion 53 at the reagent placement position E of the reagent dilution device 50, preventing the reagent barrel 200 without the groove 210 from being placed in the reagent placement position E of the reagent dilution device 50. Therefore, it can avoid the situation where reagent misaspiration occurs due to the incorrect reagent barrel 200 being placed in the reagent placement position E, resulting in contamination of the reagent and the liquid suction pipeline, and also avoid false test results in the sample analyzer 100. Secondly, by providing an electronic tag 230 on the peripheral wall 2403 of the barrel body 240, when there is no electronic tag 230 on the reagent barrel 200 or the information of the reagent stored in the electronic tag 230 does not match, even if the reagent barrel 200 can be placed in the reagent placement position E, the operator can still determine whether the reagent barrel 200 is misloaded according to the information read by the reading device 54, further ensuring that the incorrect reagent barrel 200 will not be placed in the reagent placement position E.

[0071] As Figure 3 shown, in some embodiments, the groove 210 is provided at the connection between the peripheral wall 2403 and the bottom wall 2402. In this embodiment, the position of the groove 210 is not obvious, and it has less impact on the appearance consistency of the reagent barrel 200. Of course, it is also possible to only provide the groove 210 on the peripheral wall 2403, which can be determined according to actual design needs.

[0072] As Figure 5 shown, in some embodiments, the groove 210 includes a groove bottom wall 2101 and a first groove side wall 2102. The groove bottom wall 2101 includes a first end facing the top wall 2401, and the first groove side wall 2102 connects the peripheral wall 2403 of the barrel body 240 and the first end of the groove bottom wall 2101. Among them, a fillet H is provided at the transition between the groove bottom wall 2101 and the first groove side wall 2102. In this embodiment, on the one hand, it is convenient for the protrusion 53 to be embedded in the groove 210, and on the other hand, it is convenient for cleaning the groove 210, which can prevent stains from remaining at the groove 210 and affecting the detection process.

[0073] As Figure 2 and Figure 3 shown, in some embodiments, the reagent barrel 200 further includes a handle 250, and the handle 250 is connected to the top wall 2401. In this embodiment, by providing the handle 250, it is convenient for users to transport the reagent barrel 200.

[0074] As Figure 3As shown, in some embodiments, the surrounding wall 2403 includes opposite first and second side walls 2404 and 2405, and a third side wall 2406 and a fourth side wall 2407 located between the first side wall 2404 and the second side wall 2405. The groove 210 and the electronic tag 230 are disposed on the first side wall 2404. Of course, it is not limited to the above embodiments. For example, in some other embodiments, it is also possible that the groove 210 and the electronic tag 230 are respectively disposed on different side walls of the reagent barrel 200, which can be specifically determined according to actual design requirements.

[0075] As Figure 2 and Figure 3 As shown, in some embodiments, the reagent barrel 200 includes a barrel body 240 and a barrel mouth portion 220. The barrel body 240 includes a top wall 2401, a bottom wall 2402, and a surrounding wall 2403. The surrounding wall 2403 is connected to the top wall 2401 and the bottom wall 2402. The surrounding wall 2403, the top wall 2401, and the bottom wall 2402 together enclose a receiving cavity for receiving the reagent. The surrounding wall 2403 includes opposite first and second side walls 2404 and 2405, and a third side wall 2406 and a fourth side wall 2407 located between the first side wall 2404 and the second side wall 2405. The barrel mouth portion 220 is provided with an opening 2201 connected to the top wall 2401 and communicating with the receiving cavity. The distance between the barrel mouth portion 220 and the first side wall 2404 in the horizontal direction is less than the distance between the barrel mouth portion 220 and the second side wall 2405. Among them, the first side wall 2404 is provided with a groove 210.

[0076] In some embodiments, the top wall 2401 is convexly provided with a handle 250, and the handle 250 is located on the side of the barrel mouth portion 220 close to the second side wall 2405.

[0077] In some embodiments, the top wall 2401 includes a first top wall portion 2410a and a second top wall portion 2410b connected to the first top wall portion 2410a. The first top wall portion 2410a is connected to the first side wall 2404, and the second top wall portion 2410b is connected to the second side wall 2405. The barrel mouth portion 220 is disposed on the first top wall portion 2410a, and the handle 250 is disposed on the second top wall portion 2410b. The first top wall portion 2410a is higher than the second top wall portion 2410b. By reasonably arranging the positions of the barrel mouth portion 220 and the handle 250, it is beneficial to the compactness of the structure of the reagent barrel 200.

[0078] In some embodiments, the groove 210 is disposed at the connection between the bottom wall 2402 and the first side wall 2404.

[0079] For other structures, connection relationships, extended descriptions, and beneficial effects of the reagent barrel proposed in this embodiment, reference can be made to the above embodiments, which will not be elaborated here.

[0080] As described above, it is only the specific implementation manner of the present utility model, but the protection scope of the present utility model is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present utility model can easily think of various equivalent modifications or substitutions, and these modifications or substitutions should all be covered within the protection scope of the present utility model. Therefore, the protection scope of the present utility model shall be subject to the protection scope of the claims.

Claims

1. A reagent dilution device, characterized in that: include: The carrying component has a reagent placement position, the reagent placement position is used to place a reagent barrel, the side wall of the reagent barrel is provided with a groove, and the carrying component is provided with a protrusion at the reagent placement position; as well as A pipette mechanism, comprising a pipette, the pipette being located above the reagent placement position and being slidably connected to the bearing assembly in the vertical direction, the pipette being able to extend into the reagent barrel at the reagent placement position when descending in the vertical direction, and being able to be pulled out of the reagent barrel at the reagent placement position when ascending in the vertical direction; The protrusion and the groove have a mating state and a non-mating state; Wherein, in the matched state, the projection of the suction tube on the plane perpendicular to the vertical direction is located within the range of the projection of the barrel mouth of the reagent barrel on the plane perpendicular to the vertical direction, so that when the suction tube is lowered, the suction tube can extend from the barrel mouth into the reagent barrel; In the non-matching state, the projection of the straw on a plane perpendicular to the vertical direction and the projection of the barrel mouth on a plane perpendicular to the vertical direction are offset.

2. The reagent diluting device according to claim 1, characterized in that: The bearing assembly comprises: Base plate; and The side plate assembly is connected to the bottom plate, the side plate assembly and the bottom plate together enclose the reagent placement position, and the protrusion is at least connected to the side plate assembly.

3. The reagent diluting device according to claim 2, characterized in that: The protrusion is connected to the side plate assembly and the bottom plate.

4. The reagent diluting device according to claim 2, characterized in that: The side panel assembly comprises: A first side plate connected to the bottom plate; A second side plate connected to the bottom plate, the second side plate comprising a first end and a second end, the first end of the second side plate being connected to the first side plate; a third side plate connected to the bottom plate and spaced apart from the second side plate, the third side plate comprising a first end and a second end, the first end of the third side plate being connected to the first side plate; Among them, the bottom plate, the first side plate, the second side plate and the third side plate together enclose the reagent placement position, the second end of the second side plate and the second end of the third side plate form an opening for the reagent barrel to enter the reagent placement position, and the protrusion is connected to the first side plate.

5. The reagent diluting device according to claim 4, characterized in that: The bearing assembly further includes a limiter, the limiter is connected to the first side plate and spaced apart from the bottom plate, and a slot matching the shape of the barrel mouth is provided on a side of the limiter facing away from the first side plate; In the mating state, the barrel mouth is embedded in the card slot.

6. The reagent diluting device according to claim 4, characterized in that: The reagent diluting device further comprises a reading device, the reading device is connected to the first side plate, and the reading device is used to read the electronic label arranged on the reagent barrel.

7. The reagent diluting device according to claim 1, characterized in that: The reagent diluting device further comprises a liquid quantitative delivery device, a first pipeline, a second pipeline and a third pipeline, wherein the liquid quantitative delivery device has a first inlet, a second inlet and an outlet, one end of the first pipeline is connected to the first inlet of the liquid quantitative delivery device, the other end of the first pipeline is used to be connected to a diluent providing device, the second pipeline is connected to the pipette and the second inlet of the liquid quantitative delivery device, the third pipeline is connected to the outlet of the liquid quantitative delivery device, and the liquid quantitative delivery device is used to input the diluent and the reagent into the third pipeline for mixing according to a preset ratio; or The reagent dilution device also includes a liquid quantitative delivery device, a first pipeline, a second pipeline, a third pipeline, a fourth pipeline and a mixing container. The liquid quantitative delivery device has a first chamber, a second chamber, a first inlet, a second inlet, a first outlet and a second outlet. The first inlet and the first outlet are connected to the first chamber, and the second inlet and the second outlet are connected to the second chamber. One end of the first pipeline is connected to the first inlet of the liquid quantitative delivery device, and the other end of the first pipeline is used to connect to the diluent providing device. The second pipeline connects the pipette and the second inlet of the liquid quantitative delivery device, the third pipeline connects the mixing container and the first outlet of the liquid quantitative delivery device, and the fourth pipeline connects the mixing container and the second outlet of the liquid quantitative delivery device. The liquid quantitative delivery device is used to input the diluent and the reagent into the mixing container for mixing according to a preset ratio.

8. A reagent barrel, characterized in that: include: A barrel body, comprising a top wall, a bottom wall and a surrounding wall, wherein the surrounding wall is connected to the top wall and the bottom wall, and the surrounding wall, the top wall and the bottom wall together enclose a containing cavity for containing a reagent; and The barrel mouth is provided with an opening connected to the top wall and communicating with the accommodating cavity; Wherein, the surrounding wall of the barrel body is provided with a groove and an electronic tag, and the electronic tag is at least used to store information of the reagent in the reagent barrel.

9. The reagent barrel as claimed in claim 8, characterized in that: The groove is arranged at the connection between the surrounding wall and the bottom wall.

10. The reagent barrel according to claim 8 or 9, characterized in that: The groove comprises: a groove bottom wall including a first end facing the top wall; and A first groove side wall connecting the surrounding wall of the barrel body and the first end of the groove bottom wall; There is a rounded transition between the groove bottom wall and the first groove side wall.

11. The reagent barrel according to claim 8, characterized in that: The reagent barrel further comprises a handle, wherein the handle is connected to the top wall; and / or, The surrounding wall includes a first side wall and a second side wall that are opposite to each other, and a third side wall and a fourth side wall located between the first side wall and the second side wall. The groove and the electronic tag are arranged on the first side wall.

12. A reagent barrel, characterized in that: include: A barrel body, comprising a top wall, a bottom wall and a surrounding wall, wherein the surrounding wall is connected to the top wall and the bottom wall, the surrounding wall, the top wall and the bottom wall together enclose a containing cavity for containing a reagent, the surrounding wall comprising a first side wall and a second side wall opposite to each other, and a third side wall and a fourth side wall located between the first side wall and the second side wall; and The barrel mouth is provided with an opening connected to the top wall and communicating with the accommodating cavity, and the distance between the barrel mouth and the first side wall in the horizontal direction is smaller than the distance between the barrel mouth and the second side wall; Wherein, the first side wall is provided with a groove.

13. The reagent barrel according to claim 12, characterized in that: A handle is protruding from the top wall, and the handle is located on a side of the barrel mouth close to the second side wall.

14. The reagent barrel according to claim 13, characterized in that: The top wall includes a first top wall portion and a second top wall portion connected to the first top wall portion, the first top wall portion is connected to the first side wall, the second top wall portion is connected to the second side wall, the barrel mouth portion is arranged on the first top wall portion, the handle is arranged on the second top wall portion, and the first top wall portion is higher than the second top wall portion.

15. The reagent barrel according to any one of claims 12 to 14, characterized in that: The groove is arranged at the connection between the bottom wall and the first side wall.

16. A sample analyzer, characterized in that: include: A sample dispensing device, comprising a sample needle and a sample needle driving mechanism, wherein the sample needle driving mechanism is used to drive the sample needle to draw a sample from a sample container and dispense the sample into a reaction container; A reagent dispensing device, comprising a reagent needle and a reagent needle driving mechanism, wherein the reagent needle driving mechanism is used to drive the reagent needle to absorb the reagent from the reagent container and dispense the reagent into the reaction container; a sample detection device, the sample detection device being used to detect a reaction liquid made of the sample and the reagent in the reaction container; a cleaning device, the cleaning device being used to clean the sample needle and / or the reagent needle; and The reagent dilution device according to any one of claims 1 to 7; Wherein, the reagent dilution device has at least one of the following uses: providing the reagent dispensing device with a reagent to be injected into the reaction container to react with the sample; A reagent for cleaning the sample needle and / or the reagent needle is provided to the cleaning device.

17. A sample analyzer, characterized in that: include: A sample dispensing device, used for drawing a sample from a sample container and dispensing the sample into a reaction container; A reagent dispensing device, used for drawing a reagent from a reagent container and dispensing the reagent into a reaction container, wherein the reagent includes a magnetic bead reagent; a sample detection device, used to detect a reaction solution made of the sample and the reagent in the reaction container; A magnetic bead washing and separation device, used to wash out free substances in the reaction solution; as well as The reagent dilution device according to any one of claims 1 to 7; Wherein, the reagent diluting device is used to provide the required reagents to the magnetic bead cleaning and separation device.

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