Blending carrier for sequencing micropore array chip

By designing a mixing vehicle for sequencing micropore array chips, the problem of uneven mixing in the prior art is solved, more reliable sequencing results are achieved, and multi-chip operation is supported, which improves the flexibility of use.

CN223042635UActive Publication Date: 2025-07-01CHENGDU WANZHONG FUTURE BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202422011015.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-20
Publication Date
2025-07-01
Estimated Expiration
2034-08-20

AI Technical Summary

Technical Problem

The existing sequencing micropore array chips lack special mixing vehicles during mixing, resulting in uneven mixing and affecting the reliability of sequencing.

Method used

A mixing vehicle including bottom plate, hanging ears, positioning grooves and pressing blocks is designed. The chip is positioned through the positioning grooves of the bottom plate, and the pressing blocks are fixed to the chip, and the hanging ears are connected to the mixing instrument for swaying and mixing.

Benefits of technology

This design realizes uniform mixing of sequencing micropore array chips, improves sequencing reliability, and supports multi-chip mixing operations through the design of connecting grooves and bumps, and has high flexibility in use.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a mixing carrier for sequencing a micro-array chip, which belongs to the field of biochips and comprises a bottom plate, hangers symmetrically arranged on two sides of the bottom plate, positioning grooves arranged on the bottom plate and pressing blocks arranged between the hangers and the bottom plate, and the positioning of the micro-array chip for sequencing is realized through the positioning grooves of the bottom plate. Fixing is achieved through the pressing blocks, the device can be fixed to a mixing instrument through the hanging lugs to conduct swing mixing, the structure is simple, operation is convenient, the reliability of micropore mixing can be ensured, the connecting grooves and the connecting protruding blocks are arranged on the periphery of the bottom plate, mixing operation can be conducted on multiple chips in a splicing mode, and the use flexibility is high.
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Description

Technical Field

[0001] The utility model relates to the field of biochips, in particular to a mixing carrier for sequencing micropore array chips. Background Art

[0002] A microarray chip is a chip that uses photoconductive in situ synthesis or micro-spotting methods to orderly solidify a large number of biological macromolecules such as nucleic acid fragments, polypeptide molecules, and even biological samples such as tissue sections and cells on the surface of a support (such as a glass slide, nylon membrane and other carriers) to form a dense two-dimensional molecular arrangement, which is then reacted with labeled target molecules in the biological sample to be tested, and detected and analyzed by specific instruments to determine the number of target molecules in the sample. It is currently widely used in gene sequencing, in which it is necessary to ensure that the amount of reagent in each microwell of the microarray is uniform on the chip to ensure the reliability of sequencing. Currently, this type of sequencing microarray chip is mostly mixed by oscillation, and there is currently no mixing carrier specifically for this type of chip. Utility Model Content

[0003] In view of the above problems, the utility model provides a mixing carrier for sequencing microwell array chip, which has the advantages of simple structure, convenient operation and high safety in use.

[0004] The technical solution of the utility model is:

[0005] A mixing carrier for sequencing micropore array chip comprises a bottom plate, hanging ears symmetrically arranged on both sides of the bottom plate, a positioning groove arranged on the bottom plate, and a pressing block arranged between the hanging ears and the bottom plate.

[0006] The bottom plate is a rectangular bottom plate, and the symmetrically arranged hanging ears and the bottom plate are in a "U" shape.

[0007] The symmetrically arranged hanging ears are arranged at two ends of the bottom plate in the length direction, and each hanging ear is provided with a long strip through hole along its height direction.

[0008] A first connecting groove is arranged on one side of the bottom plate in the length direction, and a first connecting protrusion corresponding to the first connecting groove is arranged on the other side.

[0009] A second connecting groove is arranged at one end of the bottom plate in the length direction, and a second connecting protrusion corresponding to the second connecting groove is arranged at the other end.

[0010] The pressing block is parallel to the bottom plate, and the pressing block includes a first pressing block and a second pressing block that are symmetrically arranged, the first pressing block is connected to one of the hanging ears, the second pressing block is connected to another hanging ear, and the hanging ears connected to the first pressing block and the bottom plate are in the shape of a "匚".

[0011] The beneficial effects of the utility model are:

[0012] Since the micro-well alignment chips for sequencing are all square, positioning is achieved through the positioning grooves on the bottom plate, fixation is achieved through the pressing blocks, and they can be fixed on the mixing instrument through the hanging ears for rocking and mixing. The structure is simple and the operation is convenient, which can ensure the reliability of micro-well mixing. Moreover, connection grooves and connection bumps are provided around the bottom plate, and multiple chips can be mixed by splicing, with high flexibility in use. Description of the Drawings

[0013] Figure 1 is the front view of a mixing carrier for a sequencing micro-well array chip according to an embodiment of the present invention;

[0014] Figure 2 is the left view of a mixing carrier for a sequencing micro-well array chip according to an embodiment of the present invention;

[0015] Figure 3 is the right view of a mixing carrier for a sequencing micro-well array chip according to an embodiment of the present invention;

[0016] Figure 4 is the top view of a mixing carrier for a sequencing micro-well array chip according to an embodiment of the present invention.

[0017] Description of the Reference Numerals:

[0018] 1 is the bottom plate, 2 is the hanging ear, 3 is the positioning groove, 4 is the pressing block, 11 is the first connection groove, 12 is the first connection bump, 13 is the second connection groove, 14 is the second connection bump, 21 is the long strip-shaped through hole, 41 is the first pressing block, and 42 is the second pressing block. Detailed Embodiments

[0019] The following further describes the embodiments of the present invention with reference to the drawings. Embodiment

[0020] As Figures 1-4 shown, a mixing carrier for a sequencing micro-well array chip includes a bottom plate 1, hanging ears 2 symmetrically arranged on both sides of the bottom plate 1, a positioning groove 3 provided on the bottom plate 1, and a pressing block 4 provided between the hanging ear 2 and the bottom plate 1.

[0021] The bottom plate 1 is a rectangular bottom plate, and the symmetrically arranged hanging ears 2 and the bottom plate 1 are in a "U" shape.

[0022] The symmetrically arranged hanging ears 2 are arranged at both ends of the bottom plate 1 in the length direction, and each hanging ear 2 is provided with a long strip-shaped through hole 21 along its height direction.

[0023] A first connection groove 11 is provided on one side of the bottom plate 1 in the length direction, and a first connection bump 12 corresponding to the first connection groove 11 is provided on the other side.

[0024] One end of the bottom plate 1 in the length direction is provided with a second connecting groove 13, and the other end is provided with a second connecting convex block 14 corresponding to the second connecting groove 13.

[0025] The pressing block 4 is parallel to the bottom plate 1. The pressing block 4 includes a first pressing block 41 and a second pressing block 42 which are symmetrically arranged. The first pressing block 41 is connected to one hanger 2, and the second pressing block 42 is connected to the other hanger 2. The first pressing block 41, the hanger 2 connected to the first pressing block 41 and the bottom plate 1 form a "C" shape.

[0026] The above embodiments only represent the specific implementation manners of the present utility model, and the description thereof is relatively specific and detailed. However, it should not be construed as a limitation to the scope of the patent of the present utility model. It should be noted that for those of ordinary skill in the art, without departing from the concept of the present utility model, several deformations and improvements can still be made, and these all belong to the protection scope of the present utility model.

Claims

1. A mixing carrier for sequencing microwell array chip, characterized in that: It includes a bottom plate, lugs symmetrically arranged on both sides of the bottom plate, a positioning groove arranged on the bottom plate, and a pressing block arranged between the lugs and the bottom plate.

2. A mixing carrier for sequencing microwell array chip according to claim 1, characterized in that: The bottom plate is a rectangular bottom plate, and the symmetrically arranged lugs and the bottom plate form a "U" shape.

3. A mixing carrier for sequencing microwell array chip according to claim 2, characterized in that: The symmetrically arranged lugs are arranged at both ends in the length direction of the bottom plate, and each lug is provided with a long through hole along its height direction.

4. A mixing carrier for sequencing microwell array chip according to claim 2, characterized in that: A first connecting groove is arranged on one side in the length direction of the bottom plate, and a first connecting convex block corresponding to the first connecting groove is arranged on the other side.

5. A mixing carrier for sequencing microwell array chip according to claim 2, characterized in that: A second connecting groove is arranged at one end in the length direction of the bottom plate, and a second connecting convex block corresponding to the second connecting groove is arranged at the other end.

6. A mixing carrier for sequencing microwell array chip according to claim 1, characterized in that: The pressing block is parallel to the bottom plate. The pressing block includes a first pressing block and a second pressing block which are symmetrically arranged. The first pressing block is connected to one of the lugs, the second pressing block is connected to the other lug, and the lug to which the first pressing block is connected and the bottom plate form a "匚" shape.