Industrial preparative chromatography distributor

Abstract

The utility model discloses an industrial preparative chromatography distributor, which belongs to the field of preparative chromatography equipment and comprises a solvent bottle arranged on a base and communicated with a liquid inlet end of a bottleneck distributor main body, and a bottle cap is sleeved at the top end of the solvent bottle; an air inlet assembly is arranged on the bottle cap; the air inlet assembly comprises an air inlet pipe fixedly inserted into the bottle cap, a fixing plate is fixedly connected into the air outlet end of the air inlet pipe, an air guide hole is formed in the fixing plate, a sliding rod is slidably inserted into the fixing plate through a through hole, the bottom end of the sliding rod is fixedly connected with a piston plate making contact with the bottom end of the fixing plate, and an elastic piece is arranged on the sliding rod. The elastic air inlet assembly can allow air to enter the bottle so as to compensate volume reduction caused by solvent extraction, maintain internal and external pressure balance and protect the container; solvent can flow smoothly by keeping the pressure in the bottle stable, and the situation that the liquid pumping speed is reduced or interrupted due to negative pressure is avoided, so that the overall efficiency and continuity of liquid pumping are improved.

Description

Technical Field

[0001] The utility model relates to the technical field of preparative chromatography equipment, in particular to an industrial preparative chromatography dispenser. Background Technique

[0002] Preparative chromatography refers to using chromatographic techniques to prepare pure substances, that is, separating and collecting one or more chromatographically pure substances; the concept of "preparation" in preparative chromatography means obtaining a sufficient amount of a single compound to meet research and other uses; the emergence of preparative chromatography has established a connection between chromatographic techniques and economic benefits; the size of the preparative amount and the cost are two important indicators of preparative chromatography; among them, gas-phase preparative chromatography is mainly used for the preparation of chromatographically pure samples of petrochemical products and volatile natural products.

[0003] After investigation, the Chinese utility model patent with the publication number CN211462171U discloses an industrial preparative chromatography dispenser, which includes a bottle mouth dispenser main body. An interface is arranged at the lower end of the bottle mouth dispenser main body, and a solvent bottle is connected to the lower end of the interface. An liquid outlet is arranged on the bottle mouth dispenser main body, and the bottle mouth dispenser main body, the liquid outlet and the interface are of an integrated structure. And the inner wall of the interface is provided with threads. A connecting plate is arranged at the front end of the bottle mouth dispenser main body, and a telescopic rod is connected to the lower end of the connecting plate. The telescopic rod is provided with a sleeve, and the lower end of the sleeve is connected to the base. And the telescopic rod and the sleeve are of a telescopic structure. The base is of an inwards concave structure, and a spring is arranged on the inner wall of the base. This industrial preparative chromatography dispenser is provided with a base with adjustable height on the bottle mouth dispenser main body. When installing the solvent bottle and the bottle mouth dispenser main body, by placing the solvent bottle into the base for fixation, the problems of easy inclination and collapse when using the solvent bottle and the bottle mouth dispenser main body are avoided. However, during the process of pumping liquid from the inside of the solvent bottle, negative pressure is easily generated inside the solvent, which may cause the bottle to deform or even be sucked flat, resulting in a slowdown or interruption of the pumping liquid speed, and the phenomenon of discontinuous pumping liquid occurs.

[0004] Therefore, the utility model provides an industrial preparative chromatography dispenser to solve the above problems. Content of the Utility Model

[0005] (1) Technical Problems to be Solved

[0006] The utility model provides an industrial preparative chromatography dispenser, aiming to solve the problems in the background technique that the existing solvent bottle connected to the dispenser lacks a ventilation structure, and negative pressure is easily generated inside the solvent during the process of pumping liquid from the inside of the solvent bottle, which may cause the bottle to deform or even be sucked flat, resulting in a slowdown or interruption of the pumping liquid speed, etc.

[0007] (2) Technical Solutions

[0008] To achieve the above object, the utility model provides the following technical solution: an industrial preparation chromatography distributor, comprising a solvent bottle arranged on a base and connected to a liquid inlet end of a bottle mouth distributor body, wherein a bottle cap is provided on the top end of the solvent bottle;

[0009] The difference from the existing dispenser is that: in order to prevent the solvent bottle from being emptied and deflated when the bottle mouth dispenser body extracts liquid from the inside of the solvent bottle, the bottle cap is provided with an air intake assembly for ventilating the solvent bottle; the air intake assembly includes an air intake pipe fixedly plugged on the bottle cap, a fixed plate fixedly connected to the air outlet end of the air intake pipe, an air guide hole is opened on the fixed plate, a sliding rod is slidably plugged on the fixed plate through the through hole, the bottom end of the sliding rod is fixedly connected to a piston plate in contact with the bottom end of the fixed plate, and the top end of the sliding rod is fixedly connected to a baffle An elastic member is arranged between the baffle and the fixed plate; the elastic air inlet assembly can allow air to enter the bottle to compensate for the volume reduction caused by the extraction of the solvent, maintain the balance of internal and external pressures, and protect the container; maintaining the stability of the pressure in the bottle can ensure smooth flow of the solvent, avoid slowing down or interrupting the extraction speed due to negative pressure, thereby improving the overall efficiency and continuity of the extraction; avoid sudden rupture or splashing caused by excessive pressure difference between the inside and outside of the bottle, reduce the risk of injury to the operator, and also protect the surrounding environment from pollution by chemical solvents.

[0010] Preferably, the elastic member is specifically a first spring, and the first spring is slidably sleeved on the outside of the sliding rod.

[0011] Preferably, a filter is fixedly embedded in the air inlet end of the air inlet pipe; compared with directly opening the bottle mouth, using an air inlet assembly with a filtering function can prevent dust, microorganisms or other contaminants from entering the solvent bottle, thereby maintaining the purity of the solvent, which is particularly important for high quality standards in laboratories and industrial production.

[0012] Preferably, a connecting hose extending into the solvent bottle is inserted into the bottle cap, and the end of the connecting hose is fixedly connected to the liquid inlet end of the bottle mouth dispenser body.

[0013] Preferably, a plurality of legs are fixedly connected to the bottom end of the base, and anti-slip pads are fixedly connected to the bottom ends of the legs.

[0014] Preferably, a clamping assembly for clamping the solvent bottle is provided on the base. The clamping assembly includes a fixed sleeve fixed on the base. A clamping plate in contact with the outer wall of the solvent bottle is slidably inserted into the fixed sleeve. A second spring is provided between the fixed sleeve and the clamping plate. A limiting groove is formed on the fixed sleeve, and a limiting rod fixedly connected to the top end of the clamping plate is slidably sleeved in the limiting groove; the top edge of the end of the clamping plate facing the solvent bottle is inclined, which facilitates the solvent bottle to squeeze the clamping plate and move towards the inside of the fixed sleeve. There are three clamping assemblies, which can then position and clamp the solvent bottle. The elastic force of the spring can ensure that the clamping plate stably positions the solvent bottle on the base.

[0015] Preferably, a wear-resistant pad is fixedly embedded at the end of the clamping plate facing the solvent bottle.

[0016] (III) Beneficial effects

[0017] This application uses an elastic air inlet assembly to allow air to enter the bottle to compensate for the volume reduction caused by the extraction of the solvent, maintain the internal and external pressure balance, and protect the container; maintaining the stability of the pressure inside the bottle can ensure smooth solvent flow, avoid the slowdown or interruption of the liquid extraction speed caused by negative pressure, thereby improving the overall efficiency and continuity of the liquid extraction; it avoids the sudden rupture or splashing that may be caused by the excessive pressure difference between the inside and outside of the bottle, reduces the risk of operator injury, and also protects the surrounding environment from chemical solvent pollution.

[0018] In this application, the top edge of the end of the clamping plate facing the solvent bottle is inclined, which facilitates the solvent bottle to squeeze the clamping plate and move towards the inside of the fixed sleeve. There are three clamping assemblies, which can then position and clamp the solvent bottle. The elastic force of the spring can ensure that the clamping plate stably positions the solvent bottle on the base. Description of the drawings

[0019] Figure 1 is a schematic diagram of the overall structure of an industrial preparation chromatographic distributor;

[0020] Figure 2 is Figure 1 the bottom view of the overall structure of an industrial preparation chromatographic distributor in

[0021] Figure 3 is a cross-sectional view of the air inlet assembly structure;

[0022] Figure 4 is a schematic diagram of a partial structure of the air inlet assembly;

[0023] Figure 5 is a schematic diagram of the clamping assembly structure.

[0024] In the figure:

[0025] 1. Base; 2. Bottle dispenser body; 3. Solvent bottle; 4. Air inlet assembly; 41. Air inlet pipe; 42. Filter; 43. Fixed plate; 44. Piston plate; 45. Slide rod; 46. Baffle; 47. First spring; 48. Air guide hole; 5. Clamping assembly; 51. Fixed sleeve; 52. Clamping plate; 53. Second spring; 54. Limit rod; 55. Limit groove; 56. Wear-resistant pad; 6. Connecting hose; 7. Support leg; 8. Anti-slip pad. DETAILED DESCRIPTION

[0026] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0027] The utility model provides an industrial preparation chromatographic distributor, such as Figures 1-5 As shown, the dispenser comprises a solvent bottle 3 which is arranged on a base 1 and is connected to a liquid inlet end of a bottle mouth dispenser body 2, and a bottle cap is provided on the top end of the solvent bottle 3;

[0028] In order to prevent the solvent bottle 3 from being emptied and deflated when the bottle mouth dispenser main body 2 draws liquid from the solvent bottle 3, an air intake component 4 for ventilating the solvent bottle 3 is provided on the bottle cap; the air intake component 4 includes an air intake pipe 41 fixedly plugged on the bottle cap, a fixed plate 43 is fixedly connected to the air outlet end of the air intake pipe 41, an air guide hole 48 is provided on the fixed plate 43, a slide rod 45 is slidably inserted on the fixed plate 43 through a through hole, a piston plate 44 in contact with the bottom end of the fixed plate 43 is fixedly connected to the bottom end of the slide rod 45, a baffle 46 is fixedly connected to the top end of the slide rod 45, and an elastic member is provided between the baffle 46 and the fixed plate 43; the air intake component 4 is used to guide air to the inside of the solvent bottle 3 when the bottle mouth dispenser main body 2 draws liquid from the solvent bottle 3, so as to prevent the solvent bottle 3 from being deflated. The occurrence of the bottle mouth dispenser body 2 is convenient for the bottle mouth dispenser body 2 to extract the liquid from the inside of the solvent bottle 3; the elastic air inlet component 4 can allow air to enter the bottle to compensate for the volume reduction caused by the extraction of the solvent, maintain the balance of internal and external pressures, and protect the container; maintaining the stability of the pressure in the bottle can ensure the smooth flow of the solvent, avoid slowing down or interrupting the extraction speed due to negative pressure, thereby improving the overall efficiency and continuity of the extraction; avoid sudden rupture or splashing caused by excessive pressure difference between the inside and outside of the bottle, reduce the risk of injury to the operator, and protect the surrounding environment from pollution by chemical solvents; the elastic air inlet component 4 is usually designed to be easy to use, and the operator can complete the extraction operation without frequently opening the cover, which is convenient and fast, and also reduces the chance of solvent volatilization and the operator being exposed to harmful solvent vapors;

[0029] When in use, when the bottle mouth dispenser body 2 sucks liquid inside the solvent bottle 3, an internal and external pressure difference will occur inside the solvent bottle 3 at this time. Then, the piston plate 44 drives the slide rod 45 and the baffle 46 to move up and down along the fixed plate 43. During the downward movement of the baffle 46, the first spring 47 is squeezed to contract and store energy. At this time, external air enters the inside of the solvent bottle 3 along the air inlet pipe 41 through the air guide hole 48 to supplement the missing pressure inside the solvent bottle 3.

[0030] Furthermore, the elastic member is specifically the first spring 47, and the first spring 47 is slidably sleeved outside the slide rod 45; the first spring 47 is initially in a squeezed and stressed state for storing energy.

[0031] Still further, a filter screen 42 is fixedly embedded in the air inlet end of the air inlet pipe 41; compared with directly opening the bottle mouth, using the air inlet assembly 4 with a filtering function can prevent dust, microorganisms or other pollutants from entering the solvent bottle 3 and maintain the purity of the solvent, which is particularly important for high-quality standards in laboratories and industrial production.

[0032] Specifically, a connecting hose 6 extending into the solvent bottle 3 is inserted into the bottle cap. The end of the connecting hose 6 is fixedly connected to the liquid inlet end of the bottle mouth dispenser body 2. The connection method between the end of the connecting hose 6 and the bottle mouth dispenser body 2 is by insertion, which is convenient for disassembling the connecting hose 6 and the bottle mouth dispenser body 2.

[0033] Specifically, a plurality of legs 7 are fixedly connected to the bottom end of the base 1, and anti-slip pads 8 are fixedly connected to the bottom ends of the legs 7. The anti-slip pads 8 are made of rubber materials with wear resistance, corrosion resistance and high hardness.

[0034] A clamping assembly 5 for clamping the solvent bottle 3 is provided on the base 1. The clamping assembly 5 includes a fixed sleeve 51 fixed on the base 1. A clamping plate 52 in contact with the outer wall of the solvent bottle 3 is slidably inserted into the fixed sleeve 51. A second spring 53 is provided between the fixed sleeve 51 and the clamping plate 52. A limiting groove 55 is formed on the fixed sleeve 51, and a limiting rod 54 fixedly connected to the top end of the clamping plate 52 is slidably sleeved in the limiting groove 55; the top edge of the end of the clamping plate 52 facing the solvent bottle 3 is inclined, which is convenient for the solvent bottle 3 to squeeze the clamping plate 52 to move inside the fixed sleeve 51. Three clamping assemblies 5 are provided, which can then position and clamp the solvent bottle 3. The elastic force of the spring can ensure that the clamping plate 52 stably positions the solvent bottle 3 on the base 1;

[0035] During use, hold the solvent bottle 3 by hand, and then squeeze the solvent bottle 3 downward between the three clamping plates 52. At this time, the clamping plates 52 move inward into the fixed sleeve 51. During the movement of the clamping plates 52, the second spring 53 is squeezed to contract and store energy. When the solvent bottle 3 moves to the opposite end of the three clamping plates 52, the clamping plates 52 are stably clamped outside the solvent bottle 3 under the action of the spring.

[0036] A wear-resistant pad 56 is fixedly embedded at one end of the clamping plate 52 facing the solvent bottle 3. The wear-resistant pad 56 can increase the friction between the clamping plate 52 and the solvent bottle 3. The wear-resistant pad 56 is made of epoxy resin paint, has good corrosion resistance, is especially alkali-resistant, has good wear resistance, forms a paint film that is both hard and elastic, and has a low shrinkage rate.

[0037] The above is only the preferred specific implementation mode of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present invention, according to the technical solution of the present invention and its inventive concept, makes equivalent substitutions or changes, and should be covered by the protection scope of the present invention.

Claims

1. An industrial preparation chromatographic distributor, comprising a solvent bottle (3) arranged on a base (1) and communicating with the liquid inlet end of a bottle mouth distributor body (2), and a bottle cap is sleeved on the top end of the solvent bottle (3); It is characterized in that: An air inlet assembly (4) for ventilating the inside of the solvent bottle (3) is arranged on the bottle cap; The air inlet assembly (4) includes an air inlet pipe (41) fixedly inserted into the bottle cap. A fixed plate (43) is fixedly connected inside the air outlet end of the air inlet pipe (41). A ventilation hole (48) is formed in the fixed plate (43). A sliding rod (45) is slidably inserted through a through hole in the fixed plate (43). A piston plate (44) in contact with the bottom end of the fixed plate (43) is fixedly connected to the bottom end of the sliding rod (45). A baffle (46) is fixedly connected to the top end of the sliding rod (45). An elastic member is arranged between the baffle (46) and the fixed plate (43).

2. The industrial preparation chromatographic dispenser according to claim 1, characterized in that: The elastic member is specifically a first spring (47), and the first spring (47) is slidably sleeved outside the sliding rod (45).

3. The industrial preparation chromatographic dispenser according to claim 1, wherein: A filter screen (42) is fixedly embedded inside the air inlet end of the air inlet pipe (41).

4. The industrial preparation chromatographic distributor according to claim 1, characterized in that: A connecting hose (6) extending into the solvent bottle (3) is inserted into the bottle cap, and the end of the connecting hose (6) is fixedly connected to the liquid inlet end of the bottle mouth distributor body (2).

5. The industrial preparation chromatographic dispenser according to claim 1, wherein: A plurality of legs (7) are fixedly connected to the bottom end of the base (1), and an anti-slip pad (8) is fixedly connected to the bottom end of the legs (7).

6. The industrial preparation chromatographic distributor according to claim 1, wherein: A clamping assembly (5) for clamping the solvent bottle (3) is arranged on the base (1). The clamping assembly (5) includes a fixed sleeve (51) fixed on the base (1). A clamping plate (52) in contact with the outer wall of the solvent bottle (3) is slidably inserted into the fixed sleeve (51). A second spring (53) is arranged between the fixed sleeve (51) and the clamping plate (52). A limiting groove (55) is formed in the fixed sleeve (51), and a limiting rod (54) fixedly connected to the top end of the clamping plate (52) is slidably sleeved in the limiting groove (55).

7. The industrial preparation chromatographic distributor according to claim 6, characterized in that: A wear-resistant pad (56) is fixedly embedded at one end of the clamping plate (52) facing the solvent bottle (3).

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