Multilayer embedding slow-release mechanism for probiotics

Abstract

The utility model discloses a probiotic multilayer embedding slow-release mechanism which comprises an anti-sticking layer, an acid-resistant gelatin layer arranged on the inner side wall of the anti-sticking layer and a bonding layer arranged in the acid-resistant gelatin layer, and further comprises a first probiotic structure arranged between the acid-resistant gelatin layer and the bonding layer, and a second probiotic structure arranged between the acid-resistant gelatin layer and the bonding layer, the first probiotic structure comprises a first slow-release outer layer arranged on the inner side wall of the acid-resistant gelatin layer and a first isolating membrane arranged on the inner side of the first slow-release outer layer. By arranging the first probiotic structure, the first slow-release outer layer is gradually consumed until the first nutrient supply cavity is exposed after the anti-sticking layer and the acid-resistant gelatin layer are completely consumed, and the first nutrient supply cavity can provide nutrients for probiotics in the first probiotic placement cavity under the action of the first isolating membrane; the activity of the first slow-release outer layer is ensured, and a layer of protection effect can be provided for the probiotics in the first probiotic placement cavity when the first slow-release outer layer is consumed up in advance.

Description

Technical Field

[0001] The utility model relates to the technical field of probiotics, in particular to a probiotic multi-layer embedding and sustained-release mechanism. Background Technique

[0002] With the progress of the times and the continuous development of technology, lactic acid bacteria can not only regulate the balance of intestinal flora, but also enhance immunity and improve other health problems of the body. The intake of appropriate lactic acid bacteria has become the need of some people. However, taking lactic acid bacteria directly not only fails to play its due role, but also is very inconvenient. Therefore, it is particularly important to propose a probiotic multi-layer embedding and sustained-release mechanism.

[0003] A probiotic bead with a multi-layer protection and sustained-release structure disclosed in the Chinese utility model patent with the application number CN215958192U is a composite layer structure composed of a third embedding agent layer located on the outermost layer, a bacterial core located inside the third embedding agent layer, and a second embedding agent filled between the bacterial core and the inner wall of the third embedding agent layer. Among them, the bacterial core is a composite layer structure composed of a core composed of probiotic bacterial sludge and a first embedding agent layer embedded outside the core; the first embedding agent is protein, saccharide substances, or a mixture of protein and saccharide substances. The utility model can reduce the influence of adverse factors such as gastric acid, choline, and bile salts on probiotics through three-layer embedding of probiotics, keep the probiotics highly active and reach the intestine smoothly, and reduce the waste of probiotics while protecting the intestinal health of consumers. The utility model is applicable to the embedding structure of various probiotics.

[0004] When the probiotic bead with the multi-layer protection and sustained-release structure is used, the probiotics are embedded in three layers to protect the probiotics, so that the probiotics remain highly active and reach the intestine smoothly. However, there are still the following defects in actual use: Since the concentration of gastric acid and bile in the human body and the taking time will affect the location where the probiotics act in the body, in the case where the sustained-release structure is consumed in advance, most of the probiotics cannot reach the predetermined location with high activity to act, resulting in the waste of probiotics. Content of the Utility Model

[0005] The purpose of the utility model is to solve the problem that due to individual reasons, when the sustained-release structure is consumed in advance, the probiotics cannot reach the predetermined location with high activity to act, resulting in waste.

[0006] To achieve the above object, the technical solution adopted by the utility model is:

[0007] A probiotic multi-layer embedding and sustained-release mechanism, including an anti-adhesion layer, an acid-resistant gelatin layer arranged on the inner side wall of the anti-adhesion layer, and an adhesive layer arranged inside the acid-resistant gelatin layer, further including:

[0008] The first probiotic structure is disposed between the acid-resistant gelatin layer and the adhesive layer. The first probiotic structure includes a first slow-release outer layer disposed on the inner sidewall of the acid-resistant gelatin layer, a first isolation membrane disposed inside the first slow-release outer layer, a first nutrient supply cavity disposed between the first slow-release outer layer and the first isolation membrane, a first slow-release inner layer disposed inside the first isolation membrane, and a first probiotic placement cavity disposed between the first isolation membrane and the first slow-release inner layer;

[0009] The nutrient supply structure is disposed on the inner sidewall of the adhesive layer and is used to provide nutrients for probiotics.

[0010] In a preferred embodiment of the present utility model, spherical through holes are uniformly formed on the first isolation membrane, and the first nutrient supply cavity and the first probiotic placement cavity communicate with each other.

[0011] In a preferred embodiment of the present utility model, the size of the through holes on the outer sidewall of the first isolation membrane is larger than the size of the through holes on the inner sidewall of the first isolation membrane.

[0012] In a preferred embodiment of the present utility model, the nutrient supply structure includes an outer isolation layer disposed on the inner sidewall of the adhesive layer, a nutrient mixture disposed on the inner sidewall of the outer isolation layer, and an inner isolation layer disposed on the inner sidewall of the nutrient mixture.

[0013] In a preferred embodiment of the present utility model, the thickness of the outer isolation layer is equal to the thickness of the inner isolation layer, and the outer isolation layer and the inner isolation layer are made of the same material.

[0014] In a preferred embodiment of the present utility model, a second probiotic structure is disposed on the inner sidewall of the inner isolation layer. The second probiotic structure includes a second slow-release layer disposed on the inner sidewall of the inner isolation layer, a second isolation membrane disposed inside the second slow-release layer, a second nutrient supply cavity disposed between the second slow-release layer and the second isolation membrane, and a second probiotic placement cavity disposed inside the second isolation membrane.

[0015] In a preferred embodiment of the present utility model, cylindrical through holes are uniformly formed on the second isolation membrane. The size of the through holes on the outer wall of the second isolation membrane is equal to the size of the through holes on the inner wall of the second isolation membrane, and the outer sidewall of the second slow-release layer abuts against the inner sidewall of the inner isolation layer.

[0016] The present utility model solves the problem in the background art that due to individual reasons, the slow-release structure is consumed in advance, and probiotics cannot maintain high activity to reach the predetermined location for action, resulting in waste. The present utility model has the following beneficial effects:

[0017] 1. In the present utility model, a probiotic multi-layer embedding and sustained-release mechanism is provided. By setting a first probiotic structure, after the anti-adhesion layer and the acid-resistant gelatin layer are consumed, the first sustained-release outer layer is gradually consumed until the first nutrient supply cavity is exposed. Under the action of the first isolation membrane, the first nutrient supply cavity can not only provide nutrients for the probiotics in the first probiotic placement cavity to ensure their activity, but also provide a protective effect for the probiotics in the first probiotic placement cavity when the first sustained-release outer layer is consumed in advance.

[0018] 2. In the present utility model, a probiotic multi-layer embedding and sustained-release mechanism is provided. By setting a nutrient supply structure, the outer isolation layer and the inner isolation layer isolate the nutrient mixture. After the adhesive layer is consumed, the components in the nutrient mixture can provide nutrients for the probiotics that have been released in the first probiotic placement cavity.

[0019] 3. In the present utility model, a probiotic multi-layer embedding and sustained-release mechanism is provided. By setting a second probiotic structure, the probiotics in the second probiotic placement cavity can effectively ensure that the probiotics can reach the intestine. Even if all the probiotics in the first probiotic placement cavity are consumed in advance, the probiotics in the second probiotic placement cavity can still reach the intestine to play a role. If the probiotics in the first probiotic placement cavity can reach the intestine, the probiotics in the second probiotic placement cavity can reach deeper into the intestine, effectively expanding the action range of the probiotics. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] The present utility model will be further described below in conjunction with the drawings and embodiments;

[0021] Figure 1 is a partial cross-sectional three-dimensional view of the preferred embodiment of the present utility model;

[0022] Figure 2 is a top cross-sectional view of the preferred embodiment of the present utility model;

[0023] Figure 3 is a side cross-sectional disassembled view of the preferred embodiment of the present utility model;

[0024] Figure 4 is the Figure 2 enlarged view of part A in the preferred embodiment of the present utility model;

[0025] Figure 5 is the Figure 3 enlarged view of part B in the preferred embodiment of the present utility model.

[0026] In the figure: 1. Anti-sticking layer; 2. Acid-resistant gelatin layer; 3. First probiotic structure; 301. First slow-release outer layer; 302. First nutrient supply cavity; 303. First isolation membrane; 304. First probiotic placement cavity; 305. First slow-release inner layer; 4. Adhesive layer; 5. Nutrient supply structure; 501. Outer isolation layer; 502. Nutrient mixture; 503. Inner isolation membrane; 6. Second probiotic structure; 601. Second slow-release layer; 602. Second nutrient supply cavity; 603. Second isolation membrane; 604. Second probiotic placement cavity. Detailed implementation mode

[0027] Now, the present utility model will be further described in detail with reference to the accompanying drawings and embodiments. These drawings are all simplified schematic diagrams, only showing the basic structure of the present utility model in a schematic manner, so they only show the components related to the present utility model.

[0028] As Figure 1 , Figure 2 , Figure 3 and Figure 4 shown, a multi-layer embedding and slow-release mechanism for probiotics includes an anti-sticking layer 1, an acid-resistant gelatin layer 2 provided on the inner side wall of the anti-sticking layer 1, and an adhesive layer 4 provided inside the acid-resistant gelatin layer 2. It further includes: a first probiotic structure 3, the first probiotic structure 3 is provided between the acid-resistant gelatin layer 2 and the adhesive layer 4. The first probiotic structure 3 includes a first slow-release outer layer 301 provided on the inner side wall of the acid-resistant gelatin layer 2, a first isolation membrane 303 provided inside the first slow-release outer layer 301, a first nutrient supply cavity 302 provided between the first slow-release outer layer 301 and the first isolation membrane 303, a first slow-release inner layer 305 provided inside the first isolation membrane 303, and a first probiotic placement cavity 304 provided between the first isolation membrane 303 and the first slow-release inner layer 305. Spherical through holes are evenly opened on the outer side wall of the first isolation membrane 303. The first nutrient supply cavity 302 and the first probiotic placement cavity 304 are interconnected. The size of the through holes on the outer side wall of the first isolation membrane 303 is larger than the size of the through holes on the inner side wall of the first isolation membrane 303.

[0029] It should be noted that after swallowing the probiotics, by providing the first probiotic structure 3, after the anti-sticking layer 1 and the acid-resistant gelatin layer 2 are consumed, the first slow-release outer layer 301 is gradually consumed until the first nutrient supply cavity 302 is exposed. Under the action of the first isolation membrane 303, the first nutrient supply cavity 302 can not only provide nutrients for the probiotics in the first probiotic placement cavity 304 to ensure their activity, but also provide a layer of protection for the probiotics in the first probiotic placement cavity 304 when the first slow-release outer layer 301 is consumed in advance.

[0030] As Figure 1 , Figure 2 , Figure 3 ,Figure 4 and Figure 5 As shown in Figure 5 , the nutrient supply structure 5 is arranged on the inner wall of the adhesive layer 4 and is used to provide nutrients for probiotics. The nutrient supply structure 5 includes an outer isolation layer 501 arranged on the inner wall of the adhesive layer 4, a nutrient mixture 502 arranged on the inner wall of the outer isolation layer 501, and an inner isolation layer 503 arranged on the inner wall of the nutrient mixture 502. The thickness of the outer isolation layer 501 is equal to the thickness of the inner isolation layer 503.

[0031] It should be noted that after the first slow-release inner layer 305 is consumed, the adhesive layer 4 begins to be consumed. By providing the nutrient supply structure 5, the outer isolation layer 501 and the inner isolation layer 503 isolate the nutrient mixture 502. After the adhesive layer 4 is consumed, the components in the nutrient mixture 502 can provide nutrients for the probiotics in the first probiotic placement cavity 304 that has been released.

[0032] As Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5 As shown in Figure 5 , the second probiotic structure 6 is arranged on the inner wall of the inner isolation layer 503. The second probiotic structure 6 includes a second slow-release layer 601 arranged on the inner wall of the inner isolation layer 503, a second isolation membrane 603 arranged inside the second slow-release layer 601, a second nutrient supply cavity 602 arranged between the second slow-release layer 601 and the second isolation membrane 603, and a second probiotic placement cavity 604 arranged inside the second isolation membrane 603. Cylindrical through holes are evenly formed on the second isolation membrane 603, and the size of the through holes on the outer wall of the second isolation membrane 603 is equal to the size of the through holes on the inner wall of the second isolation membrane 603.

[0033] It should be noted that in order to ensure that the probiotics can reach the intestine, by providing the second probiotic structure 6, the probiotics in the second probiotic placement cavity 604 effectively ensure that the probiotics can reach the intestine. Even if all the probiotics in the first probiotic placement cavity 304 are consumed in advance, the probiotics in the second probiotic placement cavity 604 can still reach the intestine to play a role. If the probiotics in the first probiotic placement cavity 304 can reach the intestine, the probiotics in the second probiotic placement cavity 604 can reach deeper into the intestine, effectively expanding the scope of action of the probiotics.

[0034] When the utility model is in use, gastric acid and bile will decompose from the outside to the inside. After the anti-adhesion layer 1 and the acid-resistant gelatin layer 2 are consumed, the first slow-release outer layer 301 is gradually consumed until the first nutrient supply cavity 302 is exposed. Under the action of the first isolation membrane 303, the first nutrient supply cavity 302 can not only provide nutrients for the probiotics in the first probiotic placement cavity 304 to ensure their activity, but also provide a protective effect for the probiotics in the first probiotic placement cavity 304 when the first slow-release outer layer 301 is consumed in advance. After the first slow-release inner layer 305 is consumed, the adhesive layer 4 begins to be consumed. The outer isolation layer 501 and the inner isolation layer 503 isolate the nutrient mixture 502. After the adhesive layer 4 is consumed, the components in the nutrient mixture 502 can provide nutrients for the probiotics in the first probiotic placement cavity 304 that have been released. The probiotics in the second probiotic placement cavity 604 effectively ensure that the probiotics can reach the intestine. Even if all the probiotics in the first probiotic placement cavity 304 are consumed in advance, the probiotics in the second probiotic placement cavity 604 can still reach the intestine to play a role. If the probiotics in the first probiotic placement cavity 304 can reach the intestine, the probiotics in the second probiotic placement cavity 604 can reach deeper into the intestine, effectively expanding the action range of the probiotics.

[0035] Based on the ideal embodiments of the present utility model as inspiration, through the above description, relevant personnel can completely make various changes and modifications without departing from the technical idea of this utility model. The technical scope of this utility model is not limited to the content in the specification, and the technical scope must be determined according to the scope of the claims.

Claims

1. A probiotic multi-layer embedding and sustained release mechanism, comprising an anti-adhesion layer (1), an acid-resistant gelatin layer (2) disposed on the inner wall of the anti-adhesion layer (1), and an adhesive layer (4) disposed inside the acid-resistant gelatin layer (2), characterized in that, It further includes: A first probiotic structure (3), the first probiotic structure (3) is disposed between the acid-resistant gelatin layer (2) and the adhesive layer (4). The first probiotic structure (3) includes a first slow-release outer layer (301) disposed on the inner sidewall of the acid-resistant gelatin layer (2), a first isolation membrane (303) disposed inside the first slow-release outer layer (301), a first nutrient supply cavity (302) disposed between the first slow-release outer layer (301) and the first isolation membrane (303), a first slow-release inner layer (305) disposed inside the first isolation membrane (303), and a first probiotic placement cavity (304) disposed between the first isolation membrane (303) and the first slow-release inner layer (305); A nutrient supply structure (5), the nutrient supply structure (5) is disposed on the inner sidewall of the adhesive layer (4) for providing nutrients for probiotics.

2. The probiotic multi-layer embedding and sustained release mechanism according to claim 1, wherein: The first isolation membrane (303) is uniformly provided with spherical through holes, and the first nutrient supply cavity (302) and the first probiotic placement cavity (304) communicate with each other.

3. The probiotic multi-layer embedding and sustained release mechanism according to claim 2, characterized in that: The size of the through holes on the outer sidewall of the first isolation membrane (303) is larger than the size of the through holes on the inner sidewall of the first isolation membrane (303).

4. A probiotic multi-layer embedding and sustained release mechanism according to claim 1, characterized in that: The nutrient supply structure (5) includes an outer isolation layer (501) disposed on the inner sidewall of the adhesive layer (4), a nutrient mixture (502) disposed on the inner sidewall of the outer isolation layer (501), and an inner isolation layer (503) disposed on the inner sidewall of the nutrient mixture (502).

5. A probiotic multi-layer embedding sustained-release mechanism according to claim 4, characterized in that: The thickness of the outer isolation layer (501) is equal to the thickness of the inner isolation layer (503).

6. The probiotic multi-layer embedding and sustained release mechanism according to claim 4, characterized in that: The inner sidewall of the inner isolation layer (503) is provided with a second probiotic structure (6). The second probiotic structure (6) includes a second slow-release layer (601) disposed on the inner sidewall of the inner isolation layer (503), a second isolation membrane (603) disposed inside the second slow-release layer (601), a second nutrient supply cavity (602) disposed between the second slow-release layer (601) and the second isolation membrane (603), and a second probiotic placement cavity (604) disposed inside the second isolation membrane (603).

7. A probiotic multi-layer embedding sustained-release mechanism according to claim 6, characterized in that: The second isolation membrane (603) is uniformly provided with cylindrical through holes, and the size of the through holes on the outer wall of the second isolation membrane (603) is equal to the size of the through holes on the inner wall of the second isolation membrane (603).

Images