Turnover chromatography device

Abstract

The utility model provides a turnover chromatography device which comprises an outer supporting frame, a chromatography column body is movably mounted in the outer supporting frame through two turnover side plates, a gear seat is arranged on one side of the middle of the outer supporting frame, a hand-cranking wheel is arranged on one side of the gear seat, and a driving motor is arranged in the hand-cranking wheel; the left side and the right side of the chromatographic column body are fixed through the two overturning side plates, and when the chromatographic column body is fixed, the upper lantern ring, the middle lantern ring and the lower lantern ring outside the chromatographic column body are fixed respectively, so that an upper site, a middle site and a lower site are fixed, and the chromatographic column body is good in fixing stability and good in stability. A gear seat and a hand-cranking wheel are further arranged on the side face of the outer supporting frame, a driving motor drives a driving gear to rotate, the driving gear is meshed with a transmission fluted disc when rotating, then a rotating shaft rod connected with the interior of the transmission fluted disc in a sleeved mode is driven, the rotating shaft rod rotates, then a chromatographic column is driven to rotate, and solid-liquid mixtures can be turned over and taken conveniently.

Description

Technical Field

[0001] The utility model belongs to the technical field of chromatography and relates to a turnable chromatography device. Background Technique

[0002] Liquid chromatography is one of the most commonly used separation and analysis methods in biochemical research, and the column chromatography system instrument is an indispensable device for liquid phase separation and analysis. This set of instruments generally should include the following instruments: a gradient mixer that can obtain an elution solvent and change its concentration according to certain requirements; a constant flow infusion pump that can drive the solvent to flow through the column body at a constant flow rate; various detectors that can detect and record the change of the concentration of the liquid flowing out of the column body, and a fraction collector that can collect each part by constant volume, fixed time or counting drops.

[0003] For the traditional chromatography device, the whole machine is fixed, and a feeding port is arranged under the column. Such a structural setting is feasible when the reactant is a liquid, but when the reactant is a solid-liquid mixture, there will be a problem of difficult material taking. By setting a turnable chromatography device and adding an open cover, the above problems can be solved. Summary of the Invention

[0004] The purpose of the utility model is to provide a turnable chromatography device to solve the problems put forward in the above background technique.

[0005] The turnable chromatography device includes an outer support frame and a chromatography column body. On both sides inside the outer support frame, there are turnable side plates. The chromatography column body is movably installed inside the outer support frame through the two turnable side plates. A middle collar is arranged at the middle position of the chromatography column body. An intermediate limit collar is installed outside the middle collar, and the side of the intermediate limit collar is fixed at the middle position of the turnable side plate through an intermediate connecting arm. On one side of the middle of the outer support frame, there is a gear seat. A driving gear is installed inside the gear seat through a gear shaft rod. On one side of the gear seat, there is a hand crank wheel. A driving motor is arranged inside the hand crank wheel, and the output end of the driving motor is connected to one end of the gear shaft rod.

[0006] In the above turnable chromatography device, a transmission gear disk is arranged on one side of the gear seat, and the transmission gear disk is meshed with the driving gear. On one side of the middle of the turnable side plate, there is a rotating shaft rod one, and the transmission gear disk is sleeved on one end of the rotating shaft rod one.

[0007] In the above turnable chromatography device, a shaft seat is arranged on one side of the middle of the outer support frame. A rotating shaft rod two is movably installed inside the shaft seat through a bearing, and one end of the rotating shaft rod two is connected to one end of the intermediate connecting arm.

[0008] In the above-mentioned reversible chromatography device, an upper collar is sleeved on the top of the chromatography column body, an upper limiting collar is sleeved outside the upper collar, a second connecting arm is arranged on the outer side of the upper limiting collar, and one end of the second connecting arm is fixed at the top position of the flipping side plate.

[0009] In the above-mentioned reversible chromatography device, a lower collar is sleeved at the bottom position of the chromatography column body, a supporting bottom plate is arranged at the bottom of the lower collar, a first connecting arm is arranged on the outer side of the supporting bottom plate, and one end of the first connecting arm is fixed at the bottom position of the flipping side plate.

[0010] In the above-mentioned reversible chromatography device, fixing seats are arranged at both ends of the middle limiting collar and the upper limiting collar, and two adjacent fixing seats are fixedly locked by a screw rod.

[0011] Compared with the prior art, the advantages of the reversible chromatography device of the present utility model are as follows: in the present application, two flipping side plates are arranged inside the outer support frame, and the left and right sides of the chromatography column body are fixed by the two flipping side plates. When the chromatography column body is fixed, the upper collar, the middle collar and the lower collar outside the chromatography column are fixed respectively, forming three fixing points at the upper, middle and lower positions, so that the fixing stability of the chromatography column body is good. A gear seat and a hand crank are also arranged at the side position of the outer support frame. When it is necessary to drive the chromatography column body to rotate, the driving motor can be used to drive the driving gear to rotate. When the driving gear rotates, it meshes with the transmission gear disc, and then drives the rotating shaft rod sleeved inside the transmission gear disc. The rotating shaft rod rotates, and then drives the chromatography column body to rotate, which is convenient for flipping and taking materials of the solid-liquid mixture. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 is a schematic structural diagram of the reversible chromatography device of the present utility model.

[0013] Figure 2 is a front structural diagram of the reversible chromatography device of the present utility model.

[0014] Figure 3 is a side structural diagram of the reversible chromatography device of the present utility model.

[0015] In the figure, 1. outer support frame; 2. chromatography column body; 3. flipping side plate; 4. shaft seat; 5. upper collar; 6. middle collar; 7. lower collar; 8. supporting bottom plate; 9. first connecting arm; 10. second connecting arm; 11. gear seat; 12. hand crank; 13. driving motor; 14. transmission gear disc; 15. upper limiting collar; 16. fixing seat; 17. rotating shaft rod 1. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0016] The following are specific embodiments of the present utility model, and in combination with the attached drawings, the technical solutions of the present utility model will be further described. However, the present utility model is not limited to these embodiments.

[0017] A reversible chromatography device includes an outer support frame 1 and a chromatography column body 2. On both sides inside the outer support frame 1, there are reversible side plates 3. The chromatography column body 2 is movably installed inside the outer support frame 1 through the two reversible side plates 3. A middle collar 6 is provided at the middle position of the chromatography column body 2. An intermediate limit collar is installed outside the middle collar 6. The side surface of the intermediate limit collar is fixed at the middle position of the reversible side plate 3 through an intermediate connecting arm. On one side of the middle of the outer support frame 1, there is a gear seat 11. A driving gear is installed inside the gear seat 11 through a gear shaft rod. On one side of the gear seat 11, there is a hand crank wheel 12. A driving motor 13 is provided inside the hand crank wheel 12, and the output end of the driving motor 13 is connected to one end of the gear shaft rod.

[0018] As Figure 1 、 Figure 2 、 Figure 3 shown, for the reversible chromatography device of the present utility model, specifically, a transmission gear disc 14 is provided on one side of the gear seat 11, and the transmission gear disc 14 is meshed and connected with the driving gear. On one side of the middle of the reversible side plate 3, there is a rotating shaft rod one 17, and one end of the transmission gear disc 14 is sleeved on the rotating shaft rod one 17. The transmission gear disc 14 and the driving gear in this application are both publicly available gear structures. The rotating shaft rod one 17 and the rotating shaft rod two are metal rod members, mainly for rotating and supporting the reversible side plate 3 and the chromatography column body 2.

[0019] As Figure 1 、 Figure 2 、 Figure 3 shown, for the reversible chromatography device of the present utility model, specifically, a shaft seat 4 is provided on one side of the middle of the outer support frame 1. A rotating shaft rod two is movably installed inside the shaft seat 4 through a bearing, and one end of the rotating shaft rod two is connected to one end of the intermediate connecting arm.

[0020] As Figure 1 、 Figure 2 、 Figure 3 shown, for the reversible chromatography device of the present utility model, specifically, an upper collar 5 is sleeved on the top of the chromatography column body 2. An upper limit collar 15 is sleeved outside the upper collar 5. A connecting arm two 10 is provided on the outer side of the upper limit collar 15, and one end of the connecting arm two 10 is fixed at the top position of the reversible side plate 3.

[0021] As Figure 1 、 Figure 2 、 Figure 3As shown in the figure, the present utility model is a flip chromatography device. Specifically, a lower collar 7 is sleeved at the bottom of the chromatography column body 2, a support bottom plate 8 is arranged at the bottom of the lower collar 7, a connecting arm one 9 is arranged on the outer side of the support bottom plate 8, and one end of the connecting arm one 9 is fixed at the bottom of the flip side plate 3.

[0022] As Figure 1 , Figure 2 , Figure 3 As shown in the figure, the present utility model is a flip chromatography device. Specifically, fixed seats 16 are arranged at both ends of the middle limit collar and the upper limit collar 15, and two adjacent fixed seats 16 are fixed and locked by a screw rod.

[0023] For the flip chromatography device of the present utility model, two flip side plates 3 are arranged inside the outer support frame 1 of the chromatography device. The flip side plates 3 are of a metal rod structure, and the two flip side plates 3 are symmetrically arranged. Installation sites are arranged at the top, middle and bottom of the flip side plates 3 to respectively fix three connecting arms. The left and right sides of the chromatography column body 2 are fixed by the two flip side plates 3. The chromatography column body 2 of this application is a publicly known column structure. When the chromatography column body 2 is fixed, the upper collar 5, the middle collar 6 and the lower collar 7 outside the chromatography column body 2 are respectively fixed, so as to form three upper, middle and lower sites for fixation. The upper, middle and bottom parts of the chromatography column body 2 are supported and limited, so that the installation stability of the chromatography column body 2 after fixation is good. A gear seat 11 and a hand crank 12 are also arranged at the side position of the outer support frame 1 of this application. When it is necessary to drive the chromatography column body 2 to rotate, the drive motor 13 is started. The drive motor 13 can drive the drive gear to rotate. When the drive gear rotates, it meshes with the transmission gear disk 14, and then drives the rotating shaft rod one 17 sleeved inside the transmission gear disk 14 to rotate. When the rotating shaft rod one 17 rotates, it further drives the chromatography column body 2 to rotate, which is convenient for the solid-liquid mixture to be flipped and taken. When the motor is not powered on, the hand crank 12 can also be directly rotated to drive the drive gear to rotate, and then the flip of the chromatography column body 2 is realized.

[0024] The content not described in detail in this specification belongs to the prior art well known to those skilled in the art. The specific embodiments described herein are only examples to illustrate the spirit of the present utility model. Those skilled in the technical field to which the present utility model belongs can make various modifications or supplements to the described specific embodiments or use similar ways to replace them, but will not deviate from the spirit of the present utility model or exceed the scope defined by the appended claims.

Claims

1. A reversible chromatography device, comprising an outer support frame (1) and a chromatography column body (2), characterized in that, On both sides inside the outer support frame (1), there are flip side plates (3) provided. Inside the outer support frame (1), a chromatography column body (2) is movably installed through two flip side plates (3). At the middle position of the chromatography column body (2), there is a middle collar (6). Outside the middle collar (6), a middle limiting collar is installed, and the side of the middle limiting collar is fixed at the middle position of the flip side plate (3) through a middle connecting arm. On one side of the middle of the outer support frame (1), there is a gear seat (11). Inside the gear seat (11), a driving gear is installed through a gear shaft rod. On one side of the gear seat (11), there is a hand crank wheel (12). Inside the hand crank wheel (12), there is a driving motor (13), and the output end of the driving motor (13) is connected to one end of the gear shaft rod.

2. The reversible chromatography device according to claim 1, characterized in that On one side of the gear seat (11), there is a transmission gear disk (14), and the transmission gear disk (14) is meshed and connected with the driving gear. On one side of the middle of the flip side plate (3), there is a first rotating shaft rod (17), and the transmission gear disk (14) is sleeved on one end of the first rotating shaft rod (17).

3. The reversible chromatography device according to claim 1, characterized in that, On one side of the middle of the outer support frame (1), there is a shaft seat (4). Inside the shaft seat (4), a second rotating shaft rod is movably installed through a bearing, and one end of the second rotating shaft rod is connected to one end of the middle connecting arm.

4. The reversible chromatography device according to claim 1, wherein At the top of the chromatography column body (2), there is an upper collar (5) sleeved. Outside the upper collar (5), there is an upper limiting collar (15) sleeved. On the outside of the upper limiting collar (15), there is a second connecting arm (10), and one end of the second connecting arm (10) is fixed at the top position of the flip side plate (3).

5. The reversible chromatography device according to claim 1, characterized in that, At the bottom position of the chromatography column body (2), there is a lower collar (7) sleeved. At the bottom of the lower collar (7), there is a support bottom plate (8). On the outside of the support bottom plate (8), there is a first connecting arm (9), and one end of the first connecting arm (9) is fixed at the bottom position of the flip side plate (3).

6. The flipable chromatography device according to claim 4, characterized in that, At both ends of the middle limiting collar and the upper limiting collar (15), there are fixing seats (16), and the two adjacent fixing seats (16) are fixed and locked through a screw.

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