Straw storage cannula and biological sample cryopreservation device

Abstract

The utility model discloses a straw storage sleeve and a biological sample cryopreservation device. The straw storage cannula comprises a cannula body, the cannula body defines a containing cavity with a top opening, the containing cavity is used for containing liquid nitrogen and a straw so that the straw can be stored through the liquid nitrogen, and a visual mark is arranged at the bottom of the cannula body; the cover body defines a cover cavity with a bottom opening and at least one cover opening, the cover opening is located on the side portion or the top of the cover cavity, the cover body is detachably arranged on the pipe body through the bottom opening, and the cover opening is used for providing a volatilization channel of the liquid nitrogen. According to the straw storage sleeve and the biological sample cryopreservation device, by arranging the containing cavity capable of containing the liquid nitrogen and the cover opening capable of enabling the liquid nitrogen to volatilize, the straw can be located in the liquid-phase liquid nitrogen environment in the containing cavity, and the preservation effect on the straw is improved. And the visual identifier is arranged, so that manual or automatic identification of straw storage sleeves can be realized conveniently.

Description

Technical Field

[0001] The present application relates to the technical field of cryopreservation of biological samples, and particularly to a straw storage sleeve and a biological sample cryopreservation device. Background Art

[0002] A straw is a storage tube for storing biological cells such as sperm, eggs, and embryos. The straw needs to be placed in a straw storage sleeve for storage. However, the straw storage sleeve in the related art has a poor storage effect on the straw. Utility Model Content

[0003] In view of the above problems, the present application is proposed to provide a straw storage sleeve and a biological sample cryopreservation device that overcome the above problems or at least partially solve the above problems.

[0004] The present application provides a straw storage sleeve, including: a tube body, the tube body defining a receiving cavity with a top opening, the receiving cavity being used for placing liquid nitrogen and straws to store the straws through the liquid nitrogen, and a visual mark being provided at the bottom of the tube body; a cover body, the cover body defining a cover cavity with a bottom opening and at least one cover opening, the cover opening being located at the side or top of the cover cavity, and the cover body being detachably disposed on the tube body through the bottom opening, the cover opening being used for providing a volatilization channel for the liquid nitrogen.

[0005] Optionally, the at least one cover opening includes a plurality of cover openings arranged at equal intervals.

[0006] Optionally, a protrusion is formed on the outer wall surface of the tube body, and / or the tube body is a single-layer structure.

[0007] Optionally, an external thread is formed at the upper end of the outer wall surface of the tube body, and an internal thread is formed at the lower end of the inner wall surface of the cover body, and the tube body and the cover body are detachably connected through the external thread and the internal thread.

[0008] Optionally, the protrusion is disposed below the external thread.

[0009] Optionally, a first chamfer is provided at the lower end of the outer wall surface of the tube body, and / or a second chamfer is provided at the upper end of the outer wall surface of the cover body.

[0010] Optionally, the tube body and the cover body are connected by a thread.

[0011] Optionally, the tube body and / or the cover body is made of a metal material.

[0012] Optionally, the diameter of the receiving cavity is between 11 mm and 12 mm, and / or the thickness of the tube body is between 0.4 mm and 0.6 mm.

[0013] The present application also provides a biological sample freezing device, including: a cavity that defines a receiving cavity, and a gaseous nitrogen storage environment is formed in the receiving cavity; any one of the above-mentioned straw storage sleeves is disposed in the receiving cavity so that the straw storage sleeve is in the gaseous nitrogen storage environment.

[0014] By providing a receiving cavity that can accommodate liquid nitrogen and a lid opening that can cause liquid nitrogen to volatilize, the straw storage sleeve and the biological sample freezing device provided by the present application can make the straw in the liquid nitrogen environment in the receiving cavity, improving the preservation effect of the straw. The setting of the visual identifier facilitates the manual or automated identification of the straw storage sleeve. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Other objects and advantages of the present application will become apparent and help to have a comprehensive understanding of the present application through the description of the present application with reference to the accompanying drawings hereinafter.

[0016] Figure 1 is a schematic structural diagram of a straw storage sleeve according to some embodiments of the present application;

[0017] Figure 2 is a schematic structural diagram of the tube body of the straw storage sleeve according to some embodiments of the present application;

[0018] Figure 3 is a schematic structural diagram of the lid of the straw storage sleeve according to some embodiments of the present application.

[0019] In the figure, 10 is the straw storage sleeve, 100 is the tube body, 110 is the protrusion, 130 is the first chamfer, 200 is the lid, 210 is the lid cavity, 220 is the lid opening, and 230 is the second chamfer. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0020] To make the purpose, technical solutions and advantages of the present application clearer, the technical solutions of the present application will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present application. Obviously, the described embodiments are one embodiment of the present application, rather than all embodiments. All other embodiments obtained by those of ordinary skill in the art based on the described embodiments of the present application without creative efforts fall within the scope of protection of the present application.

[0021] Unless otherwise defined, the technical terms or scientific terms used in the present application should have the ordinary meaning understood by those of ordinary skill in the art in the field to which the present application belongs.

[0022] This embodiment first provides a straw storage sleeve 10, Figure 1 is a schematic structural diagram of the straw storage sleeve 10 according to some embodiments of the present application;Figure 2 Schematic structural view of the tube body 100 of the straw storage sleeve 10 according to some embodiments of the present application; Figure 3 Schematic structural view of the cover body 200 of the straw storage sleeve 10 according to some embodiments of the present application.

[0023] The straw storage sleeve 10 includes a tube body 100 and a cover body 200. The tube body 100 defines a receiving cavity with a top opening, and the receiving cavity is used for placing liquid nitrogen and straws to store the straws through the liquid nitrogen. A visual identifier (specifically, it can be a number, a two-dimensional code, etc.) is provided at the bottom of the tube body 100. The cover body 200 defines a cover cavity 210 with a bottom opening and at least one cover opening 220. The cover opening 220 is located at the side or top of the cover cavity 210. The cover body 200 is detachably disposed on the tube body 100 through the bottom opening, and the cover opening 220 is used to provide a volatilization channel for the liquid nitrogen.

[0024] Straws are mainly used for cryopreservation of biological samples, such as germ cells such as semen, eggs, embryos, and tissue samples, etc. These samples can be stored for a long time after cryopreservation for subsequent research or treatment. In the field of assisted reproductive medicine, straws are widely used in processes such as semen cryopreservation. Through cryopreservation, the storage time of semen can be extended, and the success rate of assisted reproductive technology can be improved. Since the straw itself is easy to implement for those skilled in the art, it will not be elaborated here.

[0025] The straws need to be placed in the straw storage sleeve 10 for storage. The straw storage sleeve 10 can be placed in a cryobox, and the cryobox is then placed in a biological sample storage device for storage. The biological sample storage device can provide a low-temperature environment or not, for example, a low-temperature environment can be provided through liquid nitrogen (which can provide a gaseous nitrogen environment or a liquid nitrogen environment), a compression refrigeration system, etc. Correspondingly, the biological sample storage device can be a liquid nitrogen tank, a refrigerator, a cold storage, etc.

[0026] This kind of straw storage sleeve 10 can make the straws in a liquid nitrogen environment in the receiving cavity by setting a receiving cavity that can hold liquid nitrogen and a cover opening 220 that can make the liquid nitrogen volatilize, improving the preservation effect of the straws. The setting of the visual identifier facilitates the manual or automated identification of the straw storage sleeve 10.

[0027] In some embodiments, the at least one cover opening 220 includes a plurality of cover openings 220 arranged at uniform intervals. Thereby, the volatilization effect of the liquid nitrogen is ensured.

[0028] In some embodiments, a protrusion is formed on the outer wall surface of the tube body, and / or the tube body is a single-layer structure. In the related art, the tube body 100 is set as a double-layer structure, while in this embodiment, the tube body 100 is set as a single-layer structure, so as to increase the size of the accommodation cavity, thereby increasing the storage capacity. The accommodation cavity can store one or more straws. The protrusion 110 formed on the outer wall surface of the tube body 100 is convenient to be grasped. Understandably, a picking and placing device can be arranged in the biological sample storage device, and the picking and placing device can grasp the straw storage sleeve 10 by grasping the protrusion 110. Liquid nitrogen and the straw can enter the accommodation cavity through the top opening, so that the straw is stored in the accommodation cavity under the liquid nitrogen environment, improving the storage effect of the biological sample in the straw.

[0029] This straw storage sleeve 10 and the biological sample freezing device provided in this embodiment can make the straw be in the liquid nitrogen environment in the accommodation cavity by providing an accommodation cavity that can hold liquid nitrogen and a lid opening 220 that can volatilize liquid nitrogen, improving the preservation effect of the straw. The single-layer design of the tube body 100 can increase the storage capacity of the accommodation cavity, and the setting of the protrusion 110 can make the straw storage sleeve 10 easy to be grasped, which is suitable for the scenario of automated operation.

[0030] In some embodiments, the protrusion 110 includes an annular protrusion 110. The setting of the annular protrusion 110 ensures the convenience of grasping the straw storage sleeve 10.

[0031] The straw storage sleeve 10 includes a tube body 100 and a lid body 200. The tube body 100 is a single-layer structure, a protrusion 110 is formed on the outer wall surface of the tube body 100, the tube body 100 defines an accommodation cavity with a top opening, and the accommodation cavity is used for placing liquid nitrogen and straws to store the straws through the liquid nitrogen. The lid body 200 defines a lid cavity 210 with a bottom opening and at least one lid opening 220, and the lid body 200 is detachably arranged on the tube body 100 through the bottom opening, and the lid opening 220 is used for providing a volatilization channel for the liquid nitrogen.

[0032] In some embodiments, the tube body 100 and the lid body 200 are connected by threads. Specifically, an external thread is formed at the upper end of the outer wall surface of the tube body 100, an internal thread is formed at the lower end of the inner wall surface of the lid body 200, and the tube body 100 and the lid body 200 are detachably connected through the external thread and the internal thread. The connection method by threads ensures the firmness of the connection.

[0033] In some embodiments, the protrusion 110 is arranged below the external thread. Thus, it is ensured that the straw storage sleeve 10 can be well grasped when the lid body 200 is arranged on the tube body 100.

[0034] In some embodiments, the lower end of the outer wall surface of the tube body 100 has a first chamfer 130. The provision of the first chamfer 130 can play a guiding role when storing the wheat straw tube in the sleeve 10, facilitating the realization of automated operation.

[0035] In some embodiments, the upper end of the outer wall surface of the cover body 200 has a second chamfer 230. Thus, it further facilitates the realization of automated operation. For example, when there are multiple wheat straw tube storage sleeves 10 and empty spaces in the cryopreservation box, when inserting a wheat straw tube storage sleeve 10 into the empty space, the provision of the second chamfer 230 can play a guiding role to prevent the wheat straw tube storage sleeve 10 from hitting the cover body 200 of other wheat straw tube storage sleeves 10.

[0036] In some embodiments, the tube body 100 and / or the cover body 200 are made of metal materials. Thus, damage to the tube body 100 and / or the cover body 200 caused by low temperature can be avoided.

[0037] In some embodiments, the diameter of the accommodation cavity is between 11 mm and 12 mm, and / or the thickness of the tube body 100 is between 0.4 mm and 0.6 mm. Thus, while ensuring the storage capacity, the strength of the structure is guaranteed.

[0038] The present application also provides a biological sample cryopreservation device. The biological sample cryopreservation device includes a cavity and any one of the above-mentioned wheat straw tube storage sleeves 10. The cavity defines an accommodation cavity, and a gaseous nitrogen storage environment is formed in the accommodation cavity. The wheat straw tube storage sleeve 10 is disposed in the accommodation cavity so that the wheat straw tube storage sleeve 10 is in the gaseous nitrogen storage environment.

[0039] It can be understood that the biological sample cryopreservation device may include a liquid nitrogen tank, a refrigerator, a cold storage, etc. in the above embodiments.

[0040] Regarding the embodiments of the present application, it should also be noted that, without conflict, the embodiments of the present application and the features in the embodiments can be combined with each other to obtain new embodiments.

[0041] The above is only the specific implementation manner of the present application, but the protection scope of the present application is not limited thereto. The protection scope of the present application should be subject to the protection scope of the claims.

Claims

1. A straw storage sleeve, characterized in that, Comprising: A tube body, the tube body defining a receiving cavity with a top opening, the receiving cavity being used for placing liquid nitrogen and straws, so as to store the straws through the liquid nitrogen, and a visual mark being provided at the bottom of the tube body; A cover body, the cover body defining a cover cavity with a bottom opening and at least one cover opening, the cover opening being located at the side or top of the cover cavity, the cover body being detachably disposed on the tube body through the bottom opening, and the cover opening being used for providing a volatilization channel for the liquid nitrogen.

2. The straw storage sleeve according to claim 1, wherein The at least one cover opening includes a plurality of cover openings arranged at uniform intervals.

3. The straw storage sleeve according to claim 1, wherein A protrusion is formed on the outer wall surface of the tube body, and / or, the tube body is a single-layer structure.

4. The straw storage sleeve according to claim 3, wherein External threads are formed at the upper end of the outer wall surface of the tube body, and internal threads are formed at the lower end of the inner wall surface of the cover body, and the tube body and the cover body are detachably connected through the external threads and the internal threads.

5. The straw storage sleeve according to claim 4, wherein The protrusion is provided below the external threads.

6. The straw storage sleeve according to claim 1, wherein A first chamfer is provided at the lower end of the outer wall surface of the tube body, and / or, a second chamfer is provided at the upper end of the outer wall surface of the cover body.

7. The straw storage sleeve according to claim 1, wherein The tube body and the cover body are connected by threads.

8. The straw storage sleeve according to claim 1, wherein The tube body and / or the cover body are made of a metal material.

9. The straw storage sleeve according to claim 1, wherein The diameter of the receiving cavity is between 11 mm and 12 mm, and / or, the thickness of the tube body is between 0.4 mm and 0.6 mm.

10. A biological sample freezing device, characterized in that, Comprising: A cavity, the cavity defining a receiving cavity, and a gas-phase liquid nitrogen storage environment being formed in the receiving cavity; The straw storage sleeve according to any one of claims 1 to 9, the straw storage sleeve being disposed in the receiving cavity so that the straw storage sleeve is in the gas-phase liquid nitrogen storage environment.

Images