Polymerization type double-drug synthesis equipment
By designing a dual-drug synthesis device with rotating disk and scraper, the problem of manual weighing and disposal in drug synthesis is solved, synchronous quantitative delivery and mixing of drugs is achieved, and the efficiency of drug synthesis is improved.
Patent Information
- Application Number
- CN202422310670.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-23
- Publication Date
- 2025-07-22
- Estimated Expiration
- 2034-09-23
AI Technical Summary
In the prior art, the two drugs need to be manually weighed and distributed separately when synthesized, resulting in low efficiency in drug synthesis.
A polymerized dual-drug synthesis device is designed, using two rotating disks and rotating rods to achieve quantitative delivery of drugs by synchronously reprinting the drug transfer tank, and mixing with arc-shaped scrapers to reduce manual weighing steps.
The synchronous quantitative delivery and mixing of drugs is achieved, the efficiency of drug synthesis and processing is improved, manual operation time is reduced, and work efficiency is improved.
Smart Images
Figure CN223127992U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of pharmaceutical machinery, and particularly relates to a polymerization-type dual-drug synthesis device. Background Art
[0002] Polymerization-type dual-drugs refer to two drugs combined together through a certain polymerization method to form a composite drug with specific functions or characteristics. The two drugs are polymerized and combined to produce a synergistic effect and enhance the therapeutic effect. For example, one drug can increase the cellular uptake of another drug or enhance its pharmacological activity. Usually, a reaction kettle is used to synthesize the two drugs. When synthesizing the drugs, it is usually necessary to weigh the added drugs in advance so that the two drugs can be put in and mixed in proportion. Generally, the two drugs are separately weighed by manual and then put in. However, in this way, the weighing process will occur twice, consuming more time and energy, resulting in low efficiency of drug synthesis and processing. Content of the Utility Model
[0003] The utility model provides a polymerization-type dual-drug synthesis device, which has the characteristic of improving the working efficiency of drug feeding and weighing.
[0004] The utility model provides the following technical solutions: including a medicine feeding box, two medicine storage grooves are opened in the medicine feeding box, two rotating carriers are rotatably connected to the inner wall of the medicine feeding box, a plurality of medicine transfer grooves are opened on the side walls of the two rotating carriers, and the plurality of medicine transfer grooves are alternately connected to the spaces of the corresponding medicine storage grooves. Two connecting grooves, a neutralization groove and a discharge hole are opened in the medicine feeding box. When the opening of the medicine transfer groove faces downwards, it is connected to the space of the corresponding medicine transfer groove. Both of the two connecting grooves are communicated with the inner space of the neutralization groove, and the neutralization groove is communicated with the inner space of the discharge hole. A rotating rod is rotatably connected to the inner wall of the medicine feeding box, and a plurality of arc-shaped scraping plates are fixedly connected to the side wall of the rotating rod. The plurality of arc-shaped scraping plates are all slidably connected to the inner wall of the neutralization groove.
[0005] Among them, a space partition plate is slidably connected to the inner wall of each of the plurality of medicine transfer grooves, one end of the space partition plate is fixedly connected with a guiding push rod, and the guiding push rod is slidably connected to the inner wall of the rotating carrier.
[0006] Among them, inner relief grooves are opened in both of the two rotating carriers, rotating rings are rotatably connected to the inner walls of the two inner relief grooves, a plurality of regulating wedges are fixedly connected to the side walls of the rotating rings, one end of the guiding push rod is fixedly connected with a sphere, the sphere is slidably connected to the side wall of the corresponding regulating wedge, and a return spring is arranged between the sphere and the inner relief groove.
[0007] Among them, motors are installed on the inner walls of both of the inner relief grooves, and a driving gear for driving the rotating ring is installed at the output end of the motor. The driving gear is meshed and connected to the inner wall of the corresponding rotating ring.
[0008] Among them, a linkage rod is fixedly connected between the two rotating carriers, and the two rotating carriers rotate synchronously through the linkage rod. A first bevel gear is fixedly connected to the side wall of the linkage rod, and a second bevel gear is fixedly connected to the top end of the rotating rod. The second bevel gear is meshed and connected to the side wall of the first bevel gear.
[0009] The beneficial effects of the present utility model are as follows: A number of drug transfer grooves on the two rotating carriers synchronously transfer the corresponding drugs. By controlling the number of times the drug transfer grooves transfer the drugs, the dosage of the drugs can be controlled. The two drugs can be synchronously and quantitatively dispensed, eliminating the need for staff to separately weigh and dispense the two drugs, reducing the time and energy consumed for weighing the drugs, improving the drug dispensing efficiency, and thus improving the efficiency of drug synthesis and processing;
[0010] The drugs in the neutralization tank are stirred and mixed by the arc-shaped scraper, facilitating the prior mixing of the drugs when they are put into the reaction kettle, reducing the subsequent stirring and mixing time of the drugs in the reaction kettle, and improving the work efficiency.
[0011] Parts not involved in this device are the same as or can be implemented using existing technologies. Description of the Drawings
[0012] Figure 1 is a three-dimensional structural schematic diagram of the present utility model;
[0013] Figure 2 is a side-sectional structural schematic diagram of the present utility model;
[0014] Figure 3 is Figure 2 an enlarged schematic diagram of part A in
[0015] Figure 4 is a front-sectional structural schematic diagram of the present utility model.
[0016] In the figure: 1, medicine feeding box; 11, medicine storage tank; 12, connecting groove; 13, neutralization tank; 14, discharge hole; 2, rotating carrier; 21, drug transfer groove; 22, space partition board; 221, guiding push rod; 222, sphere; 223, return spring; 23, inner relief groove; 24, linkage rod; 241, first bevel gear; 3, rotating ring; 31, regulating wedge block; 32, driving gear; 4, rotating rod; 41, arc-shaped scraper; 42, second bevel gear. Detailed Embodiment
[0017] Please refer to Figures 1-4, the present utility model provides the following technical solutions: It includes a medicine feeding box 1. Two medicine storage grooves 11 are opened in the medicine feeding box 1. Two rotating carrier disks 2 are rotatably connected to the inner wall of the medicine feeding box 1. A number of medicine transfer grooves 21 are opened on the side walls of the two rotating carrier disks 2. The number of medicine transfer grooves 21 is alternately in spatial connection with the corresponding medicine storage grooves 11. Two connection grooves 12, a neutralization groove 13 and a discharge hole 14 are opened in the medicine feeding box 1. When the opening of the medicine transfer groove 21 faces downward, it is in spatial connection with the corresponding medicine transfer groove 21. The two connection grooves 12 are both in communication with the internal space of the neutralization groove 13. The neutralization groove 13 is in communication with the internal space of the discharge hole 14. A rotating rod 4 is rotatably connected to the inner wall of the medicine feeding box 1. A number of arc-shaped scraping plates 41 are fixedly connected to the side wall of the rotating rod 4. The number of arc-shaped scraping plates 41 are all slidably connected to the inner wall of the neutralization groove 13.
[0018] In this implementation scheme: The medicine feeding box 1 is installed at the top position of the reaction kettle. The medicine feeding box 1 is responsible for feeding the medicines that need to be polymerized into the reaction kettle. The medicine feeding box 1 stores two different medicines separately through the two medicine storage grooves 11. The two rotating carrier disks 2 correspond to the two medicine storage grooves 11 in position. The rotating carrier disk 2 stores and transfers the medicines through a number of medicine transfer grooves 21. When the opening of the medicine transfer groove 21 faces upward, the medicine in the medicine storage groove 11 fills the medicine transfer groove 21. The two rotating carrier disks 2 rotate synchronously, so that the two medicine transfer grooves 21 can receive the medicines in the corresponding medicine storage grooves 11 at the same time. The volumes of the number of medicine transfer grooves 21 on the same rotating carrier disk 2 are the same, so that the amount of medicine received by the number of medicine transfer grooves 21 is the same. Thus, by controlling the number of times the medicine transfer grooves 21 transfer the medicines, the amount of medicine delivered can be controlled. And the two rotating carrier disks 2 rotate synchronously, so that the two groups of medicine transfer grooves 21 can carry out the medicine transfer work at the same time. Furthermore, the two medicines can be synchronously and quantitatively delivered. There is no need for staff to separately weigh and deliver the two medicines, reducing the time and energy consumed for weighing the medicines, improving the medicine delivery efficiency, and further improving the efficiency of medicine synthesis and processing. When the medicine transfer groove 21 rotates to the opening facing downward, the medicine in the medicine transfer groove 21 slides downward into the space of the corresponding connection groove 12. The two connection grooves 12 guide the two medicines into the neutralization groove 13, and the neutralization groove 13 mixes the two medicines first. Anti-sticking coatings are provided on the contact surfaces between each component in the device and the medicine, avoiding the adhesion of the medicine and affecting the actual delivery amount, reducing the medicine residue, and facilitating the sliding and discharging of the medicine in the neutralization groove 13. The rotating rod 4 supports and drives the rotation of the number of arc-shaped scraping plates 41. The rotating rod 4 drives the number of arc-shaped scraping plates 41 to rotate. The arc-shaped scraping plates 41 stir and mix the medicine in the neutralization groove 13, facilitating the prior mixing of the medicine before it is delivered into the reaction kettle, reducing the subsequent stirring and mixing time of the medicine in the reaction kettle, and improving the work efficiency.
[0019] A space partition plate 22 is slidably connected to the inner wall of each of a number of drug transfer grooves 21. One end of the space partition plate 22 is fixedly connected to a guiding push rod 221, and the guiding push rod 221 is slidably connected to the inner wall of the rotating carrier plate 2. The space partition plate 22 corresponds to the inner diameter of the drug transfer groove 21. When the space partition plate 22 slides inside the drug transfer groove 21, it can regulate the accommodation space inside the drug transfer groove 21, so that the volume ratio of the two drug transfer grooves 21 can be regulated according to the dosing ratio of the drug, improving the accuracy of drug dosing. The rotating carrier plate 2 guides and limits the sliding of the guiding push rod 221, so that the guiding push rod 221 can drive the space partition plate 22 to move along a stable path when sliding.
[0020] Inner relief grooves 23 are formed in both of the two rotating carrier plates 2. A rotating ring 3 is rotatably connected to the inner walls of the two inner relief grooves 23. A number of regulating wedges 31 are fixedly connected to the side wall of the rotating ring 3. One end of the guiding push rod 221 is fixedly connected to a sphere 222, and the sphere 222 is slidably connected to the side wall of the corresponding regulating wedge 31. A return spring 223 is arranged between the sphere 222 and the inner relief groove 23. The inner relief groove 23 makes the middle part of the rotating carrier plate 2 in a hollow state, and the inner relief groove 23 provides space for components such as the rotating ring 3 and the guiding push rod 221. The rotating ring 3 supports a number of regulating wedges 31. The regulating wedges 31 regulate the position of the corresponding guiding push rod 221 by using the inclined plane. By controlling the rotation of the rotating ring 3 to drive a number of regulating wedges 31 to rotate, the inclined plane of the regulating wedge 31 can squeeze the sphere 222, so that the sphere 222 can drive the guiding push rod 221 and the space partition plate 22 to slide away from the rotating ring 3, and further enable the space partition plate 22 to regulate the reduction of the drug volume in the drug transfer groove 21. The return spring 223 pushes the sphere 222 in the opposite direction, so that the sphere 222 can always be in close contact with the regulating wedge 31, ensuring the stability of the position of the space partition plate 22.
[0021] Motors are installed on the inner walls of the two inner relief grooves 23. A driving gear 32 for driving the rotating ring 3 is installed at the output end of the motor. The driving gear 32 is meshed with the inner wall of the corresponding rotating ring 3. The rotating carrier plate 2 supports the motor in the inner relief groove 23. The motor drives the driving gear 32 to rotate, and the driving gear 32 drives the rotating ring 3 to rotate, so that the rotating ring 3 can drive a number of regulating wedges 31 to rotate, thereby regulating the position of the space partition plate 22, and the rotation of the rotating carrier plate 2 and the rotation of the rotating ring 3 do not interfere with each other.
[0022] A linkage rod 24 is fixedly connected between two rotating carriers 2. The two rotating carriers 2 rotate synchronously through the linkage rod 24. A first bevel gear 241 is fixedly connected to the side wall of the linkage rod 24. A second bevel gear 42 is fixedly connected to the top end of the rotating rod 4. The second bevel gear 42 is meshed and connected to the side wall of the first bevel gear 241. The two rotating carriers 2 achieve synchronous and co-directional rotation through the linkage rod 24. The motor drives the rotation of the rotating carrier 2. The rotating carrier 2 drives another rotating carrier 2 to rotate synchronously through the linkage rod 24. The linkage rod 24 drives the rotation of the first bevel gear 241. The rotating rod 4 is connected to the first bevel gear 241 through the second bevel gear 42, so that the first bevel gear 241 can drive the second bevel gear 42 to rotate, and the second bevel gear 42 drives the rotating rod 4 to rotate. Furthermore, the rotating rod 4 can complete the preliminary mixing and stirring work on the medicine inside the neutralizing groove 13 through the arc-shaped scraping plate 41.
[0023] The working principle and usage process of the present utility model: Corresponding medicines are respectively added to the two medicine storage grooves 11. Subsequently, the motors in the two inner relief grooves 23 are controlled to drive the corresponding drive gears 32 to rotate. The drive gears 32 drive the rotation rings 3 to rotate. The rotation rings 3 drive a plurality of regulating wedges 31 to rotate. The regulating wedges 31 squeeze the spheres 222, so that the spheres 222 can drive the guiding push rods 221 and the space partition plates 22 to slide away from the rotation rings 3. Furthermore, the space partition plates 22 can regulate the reduction of the medicine volume in the medicine transfer grooves 21, so that the two groups of medicine transfer grooves 21 can regulate the volume ratio of the two groups of medicine transfer grooves 21 according to the medicine feeding ratio, improving the accuracy of medicine feeding. Subsequently, the motor outside the medicine feeding box 1 is controlled to drive the rotating carrier 2 to rotate. The rotating carrier 2 drives another rotating carrier 2 to rotate synchronously through the linkage rod 24. When the opening of the medicine transfer groove 21 faces upwards, the medicine inside the medicine storage groove 11 fills the medicine transfer groove 21. When the medicine transfer groove 21 rotates to the opening facing downwards, the medicine inside the medicine transfer groove 21 slides downwards into the space of the corresponding connection groove 12. The two connection grooves 12 guide the two kinds of medicines into the neutralizing groove 13, and the neutralizing groove 13 mixes the two kinds of medicines preliminarily. At the same time, the linkage rod 24 drives the rotation of the first bevel gear 241, the first bevel gear 241 drives the rotation of the second bevel gear 42, and the second bevel gear 42 drives the rotation of the rotating rod 4. Furthermore, the rotating rod 4 can complete the preliminary mixing and stirring work on the medicine inside the neutralizing groove 13 through the arc-shaped scraping plate 41.
Claims
1. A polymeric dual-drug synthesis device, characterized in that: It includes a medicine dispensing box (1). Two medicine storage grooves (11) are provided inside the medicine dispensing box (1). Two rotary carriers (2) are rotatably connected to the inner wall of the medicine dispensing box (1). A number of medicine transfer grooves (21) are provided on the side walls of the two rotary carriers (2). The number of the medicine transfer grooves (21) is alternately in spatial connection with the corresponding medicine storage groove (11). Two connection grooves (12), a neutralization groove (13) and a discharge hole (14) are provided inside the medicine dispensing box (1). When the opening of the medicine transfer groove (21) faces downward, it is in spatial connection with the corresponding medicine transfer groove (21). The two connection grooves (12) are both in communication with the internal space of the neutralization groove (13). The neutralization groove (13) is in communication with the internal space of the discharge hole (14). A rotary rod (4) is rotatably connected to the inner wall of the medicine dispensing box (1). A number of arc-shaped scraping plates (41) are fixedly connected to the side wall of the rotary rod (4). The number of the arc-shaped scraping plates (41) are all slidably connected to the inner wall of the neutralization groove (13).
2. The polymeric dual-drug synthesis device according to claim 1, characterized in that: A number of space partition plates (22) are slidably connected to the inner walls of the medicine transfer grooves (21). One end of the space partition plate (22) is fixedly connected to a guiding push rod (221). The guiding push rod (221) is slidably connected to the inner wall of the rotary carrier (2).
3. The polymer double-drug synthesis equipment according to claim 2, characterized in that: Inner relief grooves (23) are provided inside the two rotary carriers (2). Rotary rings (3) are rotatably connected to the inner walls of the two inner relief grooves (23). A number of regulating wedge blocks (31) are fixedly connected to the side walls of the rotary rings (3). One end of the guiding push rod (221) is fixedly connected to a sphere (222). The sphere (222) is slidably connected to the side wall of the corresponding regulating wedge block (31). A return spring (223) is provided between the sphere (222) and the inner relief groove (23).
4. The polymeric dual-drug synthesis device according to claim 3, characterized in that: Motors are installed on the inner walls of the two inner relief grooves (23). The output ends of the motors are provided with driving gears (32) for driving the rotary rings (3). The driving gears (32) are meshed and connected to the inner walls of the corresponding rotary rings (3).
5. A polymeric dual-drug synthesis device according to claim 1, characterized in that: A linkage rod (24) is fixedly connected between the two rotary carriers (2). The two rotary carriers (2) rotate synchronously through the linkage rod (24). A first bevel gear (241) is fixedly connected to the side wall of the linkage rod (24). A second bevel gear (42) is fixedly connected to the top end of the rotary rod (4). The second bevel gear (42) is meshed and connected to the side wall of the first bevel gear (241).