Light-proof biological sample box

Abstract

The utility model discloses a light-proof biological sample box which comprises a shell which is made of light-proof materials, is used for shading a standard slide and a confocal special culture dish and comprises a movable door arranged on the shell and a bearing piece arranged in the shell, the bearing sheet is used for bearing a standard slide and a confocal special culture dish in the shell, the movable door is connected with the shell through a rotating shaft, the movable door is used for sealing and keeping out of light for the standard slide and the confocal special culture dish borne by the bearing sheet, and the movable door and the shell are made of the same material. According to the sample box, slide samples can be placed in batches, special confocal culture dishes can be placed in batches, the slide samples and the special confocal culture dishes can be placed at the same time, the sample carrying efficiency can be improved through the overall design, and the special confocal culture dishes are independently placed in the sample box and are convenient to take.

Description

Technical Field

[0001] The utility model relates to the field of cell biotechnology, in particular to a light-shielding biological sample box. Background Technique

[0002] Optical microscopy imaging technology is an important research tool in the research fields of biology, medicine, pharmacy, materials, etc. When carrying out work, glass slides and confocal special culture dishes are the main sample preparation methods. Glass slides can be used to prepare samples such as cells, microorganisms, and tissues. Confocal special culture dishes can be used to culture living cells and can be placed in the cell culture incubator and the living cell culture chamber of the microscope. Confocal special culture dishes can be used to prepare samples such as cells, materials, and other thicker samples.

[0003] Currently, there are glass slide boxes on the market that are specifically used to store glass slide samples. However, the existing glass slide boxes have a single function. If the cover glass is not fixed during use, there is a problem of sliding when placed vertically in the sample box.

[0004] When using a confocal special culture dish, the operator usually takes one culture dish at a time or takes multiple culture dishes stacked together. Such operations have the following problems: 1. When doing live cell experiments, taking one culture dish at a time requires opening the cell culture incubator multiple times during the experiment, which may increase the risk of cell culture contamination. 2. Stacking them together will cause the need to remove the upper ones every time the bottom culture dish is taken, which is inconvenient to operate and has low efficiency. 3. The confocal special culture dish used for immunofluorescence staining experiments needs to be stored in the dark, and the culture dish itself is not light-shielding. There is a problem of fluorescence quenching when directly taking the culture dish.

[0005] In addition, when observing two types of samples, glass slides and confocal special culture dishes, at the same time, there is no mature sample box for placing the two types of samples at the same time, and it is inconvenient to carry the samples. Content of the Utility Model

[0006] The purpose of the utility model is to provide a light-shielding biological sample box to solve the problems raised in the above background technique.

[0007] To achieve the above purpose, the utility model provides the following technical solution: A light-shielding biological sample box, comprising:

[0008] A housing, which is made of light-shielding material and is used to shield light from standard glass slides and confocal special culture dishes;

[0009] The housing includes a movable door provided on the housing and a bearing plate provided in the housing;

[0010] The bearing plate is used to carry standard glass slides and confocal special culture dishes in the housing;

[0011] The movable door is connected to the housing by a rotating shaft. The movable door is used to seal and shield light from the standard glass slides and confocal special culture dishes carried by the carrier sheet, and the movable door and the housing are made of the same material.

[0012] Preferably, a magnetic sticker is provided in the housing. The magnetic sticker is used to fix the movable door, and a magnetic sticker is also provided on the movable door.

[0013] Preferably, a bolt and a limiting rod for restricting the bolt from disengaging are provided on the housing. A circular ring for conveniently lifting the bolt is provided on the bolt, and the insertion end of the bolt is a bevel surface;

[0014] A plug hole is provided on the movable door.

[0015] Preferably, a handle is provided on the housing for transferring the light-shielded biological sample box.

[0016] Preferably, the carrier sheet is arranged in the housing through a placement groove. The placement grooves are arranged in a mirror image on both sides of the housing, and the two placement grooves are arranged longitudinally in an array.

[0017] Preferably, the placement groove is concave for stably carrying the carrier sheet.

[0018] Preferably, the carrier sheet includes a rectangular carrier sheet for carrying standard glass slides and a circular carrier sheet for carrying confocal special culture dishes;

[0019] Limiting blocks and handles are provided on both the rectangular carrier sheet and the circular carrier sheet.

[0020] Preferably, a storage box is provided on the housing. The storage box includes an outer shell and a box body, and the box body and the outer shell are connected by a rotating shaft.

[0021] Preferably, a lock catch is provided on the outer shell for limiting the box body.

[0022] Preferably, a sliding structure is further provided on the outer shell. The sliding structure includes a sliding groove provided on the outer shell and a sliding block provided on the box body and meshing with the sliding groove.

[0023] Compared with the prior art, the beneficial effects of the present utility model are as follows: The light-shielding biological sample box is small in volume, stable in structure, and convenient to carry. The sample box can place slide samples in batches, can place confocal special culture dishes in batches, can place slide samples and confocal special culture dishes at the same time, and the overall design can improve the sample carrying efficiency. The confocal special culture dishes are independently placed in the sample box, which is convenient to take and place. The box is light-shielding, which is beneficial to protecting fluorescent samples, has strong practicability, is convenient to use, the shell can place different types of samples at the same time, can improve the sample carrying efficiency, the shell is light-shielding, is beneficial to protecting fluorescent samples, and can improve the experimental efficiency and effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 is an overall schematic diagram of an embodiment of the present utility model;

[0025] Figure 2 is a schematic diagram of an open state of an embodiment of the present utility model;

[0026] Figure 3 is a schematic diagram of a rectangular carrier sheet of an embodiment of the present utility model;

[0027] Figure 4 is a schematic diagram of a circular carrier sheet of an embodiment of the present utility model;

[0028] Figure 5 is a schematic diagram of a bolt of an embodiment of the present utility model;

[0029] Figure 6 is a schematic diagram of a storage box of an embodiment of the present utility model;

[0030] Figure 7 is a schematic diagram of a sliding structure of an embodiment of the present utility model;

[0031] Figure 8 is an overall schematic diagram of another embodiment of the present utility model;

[0032] Figure 9 is a schematic diagram of an open state of another embodiment of the present utility model.

[0033] In the figure:

[0034] 1, housing; 2, movable door; 3, placement groove

[0035] 4, carrier sheet; 5, storage box; 11, handle

[0036] 13, magnetic sticker; 14, bolt; 141, ring

[0037] 142, limiting rod; 41, rectangular carrier sheet; 42, circular carrier sheet

[0038] 43, limiting block; 44, handle; 51, outer shell

[0039] 52. Box body, 53. Lock catch, 54. Sliding structure

[0040] 541. Slide groove, 542. Slide block Detailed implementation manner

[0041] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without creative efforts shall fall within the protection scope of the present utility model.

[0042] Such as Figures 1-5As shown in the figure, the present utility model provides a technical solution: a light-shielding biological sample box, including: a housing 1, the housing 1 is made of light-shielding material, effectively shielding light for standard glass slides and confocal special culture dishes to prevent the standard glass slides and confocal special culture dishes from being exposed to strong light, preventing fluorescence quenching, and being used for shielding light for standard glass slides and confocal special culture dishes. The housing 1 is 85 mm long, 50 mm wide, and 100 mm high, and can place standard glass slides with a specification of 25.4 mm X 72.6 mm and confocal special culture dishes with a diameter of 35 mm. The standard glass slides and confocal special culture dishes are immunofluorescent staining samples. Four rubber bases are provided at the bottom of the housing 1 to ensure that there is no deviation in the position when the entire device is placed. A handle 11 for conveniently lifting the housing 1 is provided on the housing 1, which is convenient for handling and lifting when the entire device is moved. Two magnetic stickers 13 are provided in the housing 1. The two magnetic stickers 13 are arranged at the inner top of the housing 1 and can be adsorbed and fixed when the movable door 2 is closed, preventing the movable door 2 from suddenly opening during handling, resulting in the loss of fluorescence quenching caused by the sudden exposure of the standard glass slides and confocal special culture dishes to strong light. The magnetic sticker 13 is used to fix the movable door 2. The length and width dimensions of the movable door 2 are the same as those of the housing 1 in length and width, ensuring that no light leaks when the movable door 2 is closed. Magnetic stickers 13 are also provided on the movable door 2, which cooperate with the magnetic stickers 13 on the housing 1 for adsorption and closing to ensure that no gaps are left. A recessed handle is provided on the movable door 2 for conveniently controlling the movable door 2. An installation groove 3 is provided in the housing 1. The installation groove 3 is used to support the carrier sheet 4 to ensure that the carrier sheet 4 can be connected inside the housing 1. There are at least four installation grooves 3. In this way, according to the actual use situation, the carrier sheet 4 can be placed on the installation grooves 3 at different positions, thereby adjusting the distance between the carrier sheets 4. They are oppositely arranged on both sides in the housing 1. The installation grooves 3 on both sides can stably support the carrier sheet 4, and the installation grooves 3 on both sides are longitudinally arranged in an array. Since the number of installation grooves 3 is several, the distance can be freely adjusted. In this way, the housing 1 can place at most five confocal special culture dish sample racks and can place at most ten culture dishes at the same time. The installation groove 3 is used to support the carrier sheet 4. The installation groove 3 is concave to stably carry the carrier sheet 4, ensuring that the carrier sheet 4 will not fall out due to the unstable position of the housing 1 when the movable door 2 is opened, resulting in material loss. A movable door 2 is provided on the housing 1. The carrier sheet 4 is used to carry the standard glass slides and confocal special culture dishes, perform a limiting process on the standard glass slides and confocal special culture dishes, and stably connect the standard glass slides and confocal special culture dishes to ensure that they will not become detached during the movement of this device, resulting in sample damage. The carrier sheet 4 includes a rectangular carrier sheet 41 for carrying standard glass slides and a circular carrier sheet 42 for carrying confocal special culture dishes. The rectangular carrier sheet 41 is 80 mm long and 40 mm wide, with a hollow in the middle and raised card slots at the four corners, which can fix the sample.On the outside, there are handles 44. The positions of the handles 44 are staggered for convenient taking. The circular carrier 42 is 80 mm long and 40 mm wide, with a hollow in the middle and raised card slots for fixing samples. Two confocal special culture dishes can be placed in parallel on one circular carrier 42. On the outside, there are handles 44. The positions of the handles 44 are staggered for convenient taking. Both the rectangular carrier 41 and the circular carrier 42 are provided with limit blocks 43 and handles 44. The limit blocks 43 are set according to the sizes of the cover glass slides and the confocal special culture dishes, and can fit onto the cover glass slides and the confocal special culture dishes to ensure that accidents are reduced during carrying and moving. The handles 44 are used for convenient taking and placing of the carrier 4 for carrying samples. Since the carriers 4 are stacked, the positions of the handles 44 provided on the same type of carriers 4 are different. The advantage of this design is that when taking, it will not be inconvenient to take due to the carriers 4 stacked too closely. On the housing 1, there are bolts 14 and a limit rod 142 for restricting the separation of the bolt 14. The bolt 14 is used to lock the movable door 2 to ensure that the movable door 2 does not accidentally open due to the magnetic attraction control of the magnetic sticker 13 being disengaged during carrying. The limit rod 142 is used to connect the bolt 14 to the inner top of the housing 1 to ensure that the bolt 14 is not lost. The bolt 14 is provided with a ring 141 for convenient lifting. The ring 141 is used to control the bolt 14, and as shown in Figure 5 ..., the bolt 14 is provided with a round hole for accommodating the ring 141 to ensure that the ring 141 can rotate freely on the bolt 14 for convenient operation. The insertion end of the bolt 14 is beveled. With this design, when the movable door 2 is closed and the bevel surfaces of the movable door 2 and the bolt 14 come into contact, the bolt 14 moves upward under the pressure exerted by the movable door 2. After the movable door 2 is adsorbed and fixed by the magnetic sticker 13, the bolt 14 automatically drops and is inserted into the insertion hole of the movable door 2 to complete self-locking. The movable door 2 is provided with an insertion hole, and the size of the insertion hole is the same as that of the bolt 14. The movable door 2 is connected to the housing 1 through a rotating shaft, which can ensure that the movable door 2 can be opened freely for convenient taking of the samples stored in the housing 1. The movable door 2 is used to seal the housing 1, and the movable door 2 and the housing 1 are made of the same material, a light-blocking material.

[0043] In some embodiments of the present invention, such as Figures 6-7As shown, a storage box 5 is provided on the shell 1, and the number of the storage boxes 5 is two. The two storage boxes 5 are arranged in a mirror image on both sides of the shell 1, and are used to store some small tools dedicated to cell biology, which increases the functionality of the device. The storage box 5 includes an outer shell 51 and a box body 52. The outer shell 51 is used to connect the box body 52 and is also used to close the box body 52. The box body 52 can rotate outwardly through a rotating shaft. When it rotates outward, the sealed box body 52 separated from the outer shell 51 automatically opens. The box body 52 and the outer shell 51 are connected by a rotating shaft, which allows the box body 52 to rotate. A connecting rotating shaft is provided at the top center of the outer shell 51. A lock buckle 53 is provided on the outer shell 51. The lock buckle 53 is arranged on the connecting rotating shaft. The lock buckle 53 can close and fix the outer shell 51. The lock buckle 53 is locked on the fixing rod of the box body 52 to achieve a fixing effect, which is used to limit the box body 52. A sliding structure 54 is also provided on the shell 51. The sliding structure 54 is used to limit the outward rotation of the box body 52 and pull the box body 52. The sliding structure 54 includes a slide groove 541 arranged on the shell 51, and the slide groove 541 is fixed on the inner side of the shell 51. The slide groove 541 is used to accommodate the sliding block 542 sliding on the inner side, and a slider 542 arranged on the box body 52 and engaged with the slide groove 541. The slider 542 can slide in the slide groove 541 without being separated from the slide groove 541, thereby effectively achieving a limiting effect. The slide groove 541 has an arc to match the rotation of the slider 542 following the box body 52.

[0044] like Figure 8As shown, according to the above, this embodiment is a light-shielding biological sample box, including: a housing 1, the housing 1 is made of light-shielding material, there are two magnetic stickers 13 in the housing 1, and the two magnetic stickers 13 are arranged at the inner top of the housing 1. When the movable door 2 is closed, they can be adsorbed and fixed to prevent the movable door 2 from suddenly opening during handling, causing the standard glass slide and the confocal special culture dish to suddenly contact strong light and resulting in the loss of fluorescence quenching. The magnetic sticker 13 is used to fix the movable door 2. The length and width dimensions of the movable door 2 are the same as those of the housing 1 to ensure that when the movable door 2 is closed, no light leakage occurs. There is also a magnetic sticker 13 on the movable door 2, which cooperates with the magnetic sticker 13 on the housing 1 for adsorption and closing to ensure that no gap is left. There is a recessed handle on the movable door 2 for convenient operation of the movable door 2. The placement groove 3 is used to support the carrier sheet 4. The placement groove 3 is concave to stably support the carrier sheet 4 and ensure that the carrier sheet 4 will not fall out due to the unstable placement position of the housing 1 after the movable door 2 is opened, causing loss of materials. There is a movable door 2 on the housing 1. The carrier sheet 4 is used to carry the standard glass slide and the confocal special culture dish, perform a limiting process on the standard glass slide and the confocal special culture dish, and stably connect the standard glass slide and the confocal special culture dish to ensure that they will not become detached when the device is moved. The carrier sheet 4 includes a rectangular carrier sheet 41 for carrying the standard glass slide and a circular carrier sheet 42 for carrying the confocal special culture dish. The middle of the rectangular carrier sheet 41 is hollowed out, and there are raised card slots at the four corners to fix the sample. There is a handle 44 on the outside, and the positions of the handles 44 are staggered for convenient taking. The circular carrier sheet 42 is provided with raised card slots to fix the sample. Two confocal special culture dishes can be placed in parallel on one circular carrier sheet 42. There is a handle 44 on the outside, and the positions of the handles 44 are staggered for convenient taking. Both the rectangular carrier sheet 41 and the circular carrier sheet 42 are provided with limit blocks 43 and handles 44. The positions of the handles 44 on the same type of carrier sheet 4 are different. The advantage of this design is that it is not inconvenient to take the stacked carrier sheets 4 that are too tightly stacked. There is a bolt 14 and a limiting rod 142 for restricting the bolt 14 from detaching on the housing 1. The bolt 14 is used to lock the movable door 2 to ensure that the movable door 2 will not accidentally open due to accidental circumstances and break away from the magnetic control of the magnetic sticker 13 during carrying. The limiting rod 142 is used to connect the bolt 14 to the inner top of the housing 1 to ensure that the bolt 14 will not be lost. There is a ring 141 for convenient lifting on the bolt 14. The ring 141 is used to control the bolt 14, and the bolt 14 is as Figure 5As shown, a circular hole is provided on the upper part for accommodating a circular ring 141, so as to ensure that the circular ring 141 can rotate freely on the latch 14 for easy operation. The insertion end of the latch 14 is an inclined surface. Such a design is that when the movable door 2 is closed, when the movable door 2 and the inclined surface of the latch 14 are in contact, the latch 14 is subjected to the pressure of the movable door 2 and moves upward. After the movable door 2 is adsorbed and fixed by the magnetic sticker 13, the latch 14 automatically falls down and is plugged into the plug-in hole of the movable door 2 to complete self-locking. A plug-in hole is provided on the movable door 2, and the size of the plug-in hole is consistent with the size of the latch 14.

[0045] The latch 14 is lifted up through the circular ring 141, and then the movable door 2 is opened using the recessed handle. The rectangular carrier sheet 41 and the circular carrier sheet 42 loaded with samples are placed on the placement groove 3 in the shell 1 through the handle 44, and then the movable door 2 is closed. When the movable door 2 approaches the shell 1, it is automatically adhered by the magnetic sticker 13, and the latch 14 automatically falls down to lock the movable door 2.

[0046] like Figure 9 As shown, according to the above, in this embodiment, a storage box 5 is provided on the shell 1, and the number of the storage boxes 5 is two. The two storage boxes 5 are arranged in a mirror image on both sides of the shell 1, and are used to store some small tools dedicated to cell biology, which increases the functionality of the device. The storage box 5 includes an outer shell 51 and a box body 52. The outer shell 51 is used to connect the box body 52 and is also used to close the box body 52. The box body 52 can be rotated outwardly through the shaft. When it rotates outward, the sealed box body 52 separated from the outer shell 51 automatically opens. The box body 52 and the outer shell 51 are connected by a shaft, which allows the box body 52 to rotate. A connecting shaft is provided at the top center of the outer shell 51, and a lock buckle 53 is provided on the outer shell 51. The lock buckle 53 is arranged on the connecting shaft, and the lock buckle 53 can be used to lock the outer shell 51 is closed and fixed, and the lock buckle 53 is locked on the fixing rod of the box body 52 to achieve a fixing effect, which is used to limit the box body 52. A sliding structure 54 is also provided on the shell 51. The sliding structure 54 is used to limit the outward rotation of the box body 52 and pull the box body 52. The sliding structure 54 includes a slide groove 541 arranged on the shell 51, the slide groove 541 is fixed on the inner side of the shell 51, the slide groove 541 is used to accommodate the sliding block 542 sliding on the inner side, and a slider 542 arranged on the box body 52 and engaged with the slide groove 541. The slider 542 can slide in the slide groove 541 without being separated from the slide groove 541, thereby effectively achieving a limiting effect. The slide groove 541 has an arc to match the rotation of the slider 542 following the box body 52.

[0047] The box body 52 is pulled outward, the box body 52 rotates outward through the shaft, and is limited by the sliding structure 54 . The box body 52 is opened, and tools are loaded in the box body 52 . Then, the box body 52 is buckled and fixed by the lock buckle 53 .

[0048] Although embodiments of the present utility model have been shown and described, those of ordinary skill in the art can understand that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principle and spirit of the present utility model. The scope of the present utility model is defined by the appended claims and their equivalents.

Claims

1. A light-shielding biological sample box, characterized in that, Comprising: A housing made of light-shielding material for shielding a standard glass slide and a confocal special culture dish; The housing includes a movable door provided on the housing and a carrier sheet provided in the housing; The carrier sheet is used to carry a standard glass slide and a confocal special culture dish in the housing; The movable door is connected to the housing by a rotating shaft. The movable door is used to seal and shield the standard glass slide and the confocal special culture dish carried by the carrier sheet, and the movable door and the housing are made of the same material.

2. The light-shielding biological sample box according to claim 1, wherein: A magnetic sticker is provided in the housing for fixing the movable door, and a magnetic sticker is also provided on the movable door.

3. A light-shielding biological sample box according to claim 1 or 2, characterized in that: A bolt and a limiting rod for preventing the bolt from detaching are provided on the housing. A ring is provided on the bolt for conveniently lifting the bolt, and the insertion end of the bolt is beveled; A plug hole is provided on the movable door.

4. A light-shielding biological sample box according to claim 1, characterized in that: A handle is provided on the housing for transferring the light-shielding biological sample box.

5. The light-shielding biological sample box according to claim 1, wherein: The carrier sheet is provided in the housing through a placement groove. The placement grooves are mirror-symmetrically arranged on both sides in the housing, and the two placement grooves are longitudinally arranged in an array.

6. The light-shielding biological sample box according to claim 5, wherein: The placement groove is concave for stably carrying the carrier sheet.

7. A light-shielding biological sample box according to any one of claims 1, 5, and 6, characterized in that: The carrier sheet includes a rectangular carrier sheet for carrying a standard glass slide and a circular carrier sheet for carrying a confocal special culture dish; Limit blocks and handles are provided on both the rectangular carrier sheet and the circular carrier sheet.

8. The light-shielding biological sample box according to claim 1, characterized in that: A storage box is provided on the housing. The storage box includes an outer shell and a box body, and the box body and the outer shell are connected by a rotating shaft.

9. The light-shielding biological sample box according to claim 8, characterized in that: A lock catch is provided on the outer shell for limiting the box body.

10. A light-shielding biological sample box according to claim 8 or 9, characterized in that: A sliding structure is further provided on the outer shell. The sliding structure includes a chute provided on the outer shell and a slider provided on the box body and engaged with the chute.

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