Hydrogel microsphere preparation device

By combining up and down mixing and stirring mechanisms, uniform mixing of materials during hydrogel microsphere preparation is achieved, and the problem of uneven mixing of materials in the prior art is solved, thereby improving the uniformity of emulsion and the quality of hydrogel microspheres.

CN223144574UActive Publication Date: 2025-07-25WUHAN TEXTILE UNIV
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Patent Information

Application Number
CN202422314414.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-20
Publication Date
2025-07-25
Estimated Expiration
2034-09-20

AI Technical Summary

Technical Problem

The existing stirring mechanism can only perform lateral stirring, resulting in uneven mixing of materials during the preparation of hydrogel microspheres, affecting the uniformity of the emulsion.

Method used

The design of combining the up and down mixing mechanism and the stirring mechanism is adopted. The first motor drives the swing of the turntable and the swing rod to achieve up and down mixing of the material. At the same time, the second motor drives the stirring shaft for horizontal stirring to ensure uniform mixing of the material.

Benefits of technology

The uniform mixing of materials is achieved to form a uniform emulsion, which improves the preparation quality of hydrogel microspheres.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of hydrogel microsphere preparation, and discloses a hydrogel microsphere preparation device which comprises a preparation box, a discharge pipe, up-down mixing mechanisms and a stirring mechanism, the top of the preparation box is provided with three up-down mixing mechanisms extending into the preparation box, and the bottom of the preparation box is provided with the stirring mechanism extending into the preparation box. The up-down mixing mechanism comprises a first motor, a turntable, a swing rod, a guide rod, a box body, a first pin shaft and a second pin shaft, the first motor is fixed on the preparation box, the turntable is fixed on an output shaft of the first motor, the swing rod is mounted on the turntable, the upper end of the swing rod is rotatably connected with the turntable through the first pin shaft, and the lower end of the swing rod is rotatably connected with the guide rod through the second pin shaft; the guide rod extends into the preparation box and is in sliding connection with the preparation box, and a plurality of box bodies are fixed to the guide rod. According to the utility model, materials are mixed up and down while being transversely stirred, so that the materials are mixed more uniformly, and uniform emulsion is obtained.
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Description

Technical Field

[0001] The utility model relates to the technical field of hydrogel microsphere preparation, in particular to a hydrogel microsphere preparation device. Background Technique

[0002] Hydrogel microspheres are a kind of refined micro-structured substances, which are spherical in macroscopic shape and have excellent physical absorption ability. Hydrogel microspheres themselves are composed of a hydrogel composition, which has better absorption ability than ordinary microparticles and can absorb and solidify liquids more effectively. Its application fields are very wide and are suitable for the production and processing in departments such as food and medicine, and can be used as nutritional supplements and cell regulating substances of organisms.

[0003] There are methods such as the emulsification method, microfluidic technology, and template method for preparing hydrogel microspheres. Among them, the emulsification method is simple to operate and is widely used. When preparing hydrogel microspheres by the emulsification method, it is necessary to first disperse the precursor solution of the hydrogel in the oil phase to form an emulsion, and through an initiation polymerization reaction, the hydrogel forms microspheres in the emulsion droplets. At present, when making an emulsion, the precursor solution of the hydrogel and the oil phase are stirred by a stirring mechanism, and the existing stirring mechanisms all perform horizontal stirring alone and cannot mix the materials up and down, which easily leads to uneven up and down mixing of the materials, resulting in uneven formation of the emulsion and affecting the subsequent polymerization reaction. Therefore, in view of the above current situation, there is an urgent need to develop a hydrogel microsphere preparation device that can perform horizontal stirring on the materials while mixing the materials up and down, so that the mixing of the materials is more uniform, in order to obtain a uniform emulsion, to overcome the deficiencies in current practical applications and meet the current needs. Summary of the Utility Model

[0004] The purpose of the utility model is to provide a hydrogel microsphere preparation device to solve the problems raised in the above background technique.

[0005] In order to achieve the above purpose, the utility model adopts the following technical scheme:

[0006] A hydrogel microsphere preparation device, comprising a preparation tank, a discharge pipe, an upper and lower mixing mechanism, and a stirring mechanism. Three upper and lower mixing mechanisms extending into the interior are installed at the top of the preparation tank, and a stirring mechanism extending into the interior is installed at the bottom of the preparation tank. The upper and lower mixing mechanism includes: a first motor, a turntable, a swing rod, a guide rod, a box body, a first pin shaft, and a second pin shaft. The first motor is fixed on the preparation tank, a turntable is fixed on the output shaft of the first motor, a swing rod is installed on the turntable, the upper end of the swing rod is rotationally connected to the turntable through the first pin shaft, the lower end of the swing rod is rotationally connected to the guide rod through the second pin shaft, the guide rod extends into the preparation tank, the guide rod is slidably connected to the preparation tank, and a plurality of box bodies are fixed on the guide rod. The stirring mechanism includes: a second motor, a first gear, a second gear, and a stirring shaft. The second motor is fixed at the bottom of the preparation tank, a first gear is installed on the output shaft of the second motor, a second gear engaged with it is installed on one side of the first gear, the second gear is installed at the bottom of the stirring shaft, and the stirring shaft is rotationally connected to the preparation tank.

[0007] Preferably: The three upper and lower mixing mechanisms are evenly distributed in a circular shape with the central axis of the preparation tank as the reference.

[0008] Preferably: The preparation tank is made of a transparent material.

[0009] Preferably: A feeding port is provided at the top of the preparation tank, and a plug is detachably installed on the feeding port.

[0010] Preferably: A discharge pipe is provided at the lower end of the preparation tank, and a valve is installed on the discharge pipe.

[0011] The beneficial effects of the present invention are as follows: When using this hydrogel microsphere preparation device, the precursor solution and oil-phase material for preparing hydrogel microspheres are added into the preparation tank. The second motor drives the first gear, the second gear, and the stirring shaft to rotate, and the stirring shaft horizontally stirs the materials. At the same time, the first motor drives the turntable to rotate, the turntable drives the swing rod to swing, and the swing rod drives the guide rod and the box body to move up and down. When the box body moves down, the materials in the upper layer of the preparation tank are extruded downward, so that the upper and lower layer materials are mixed more evenly, in order to form a uniform emulsion. In summary, the present invention horizontally stirs the materials while mixing the materials up and down, making the mixing of the materials more uniform, so as to obtain a uniform emulsion. Description of the Drawings

[0012] Figure 1 It is a three-dimensional structural schematic diagram of the present invention.

[0013] Figure 2 It is an internal view of the present invention.

[0014] Figure 3 Partial structural schematic diagram of the present utility model Figure 1 .

[0015] Figure 4 Partial structural schematic diagram of the present utility model Figure 2 .

[0016] Figure 5 Partial structural schematic diagram of the present utility model Figure 3 .

[0017] Legend description:

[0018] 1. Preparation box; 101. Feeding port; 102. Plug; 2. Discharge pipe; 201. Valve; 3. Upper and lower mixing mechanism; 301. First motor; 302. Turntable; 303. Swing rod; 304. Guide rod; 305. Box body; 306. First pin shaft; 307. Second pin shaft; 4. Stirring mechanism; 401. Second motor; 402. First gear; 403. Second gear; 404. Stirring shaft. Specific implementation manners

[0019] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all of the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present utility model.

[0020] The following gives specific embodiments.

[0021] See Figures 1 to 5, in the embodiment of the present utility model, a hydrogel microsphere preparation device includes a preparation tank 1, a discharge pipe 2, an up-and-down mixing mechanism 3 and a stirring mechanism 4. The preparation tank 1 is made of a transparent material so as to clearly see the stirring situation inside the preparation tank 1. A feeding port 101 is provided at the top of the preparation tank 1, and a plug 102 is detachably installed on the feeding port 101. A discharge pipe 2 is provided at the lower end of the preparation tank 1, and a valve 201 is installed on the discharge pipe 2. Three up-and-down mixing mechanisms 3 extending into the interior thereof are installed at the top of the preparation tank 1. The three up-and-down mixing mechanisms 3 are evenly distributed in a circular shape with the central axis of the preparation tank 1 as the reference. A stirring mechanism 4 extending into the interior thereof is installed at the bottom of the preparation tank 1. The up-and-down mixing mechanism 3 includes: a first motor 301, a turntable 302, a swing rod 303, a guide rod 304, a box body 305, a first pin shaft 306 and a second pin shaft 307. The first motor 301 is fixed on the preparation tank 1, a turntable 302 is fixed on the output shaft of the first motor 301, a swing rod 303 is installed on the turntable 302. The upper end of the swing rod 303 is rotatably connected to the turntable 302 through the first pin shaft 306, and the lower end of the swing rod 303 is rotatably connected to the guide rod 304 through the second pin shaft 307. The guide rod 304 extends into the preparation tank 1, and the guide rod 304 is slidably connected to the preparation tank 1. A plurality of box bodies 305 are fixed on the guide rod 304. During use, the precursor solution and the oil-phase material for preparing the hydrogel microspheres are added into the preparation tank 1, and the materials are horizontally stirred by the stirring mechanism 4. At the same time, the first motor 301 drives the turntable 302 to rotate, the rotation of the turntable 302 drives the swing rod 303 to swing, and the swing of the swing rod 303 drives the guide rod 304 and the box body 305 to move up and down. When the box body 305 moves downward, the materials in the upper layer of the preparation tank 1 are extruded downward, so that the upper and lower layer materials are more evenly mixed to form a uniform emulsion, and then the emulsion is made into hydrogel microspheres through a polymerization reaction.

[0022] The stirring mechanism 4 includes: a second motor 401, a first gear 402, a second gear 403 and a stirring shaft 404. The second motor 401 is fixed at the bottom of the preparation tank 1, a first gear 402 is installed on the output shaft of the second motor 401, a second gear 403 meshing with the first gear 402 is installed on one side of the first gear 402, the second gear 403 is installed at the bottom of the stirring shaft 404, and the stirring shaft 404 is rotatably connected to the preparation tank 1. During use, the second motor 401 drives the first gear 402, the second gear 403 and the stirring shaft 404 to rotate, and the materials are stirred by the stirring shaft 404.

[0023] Working principle: When the hydrogel microsphere preparation device is in use, the precursor solution for preparing hydrogel microspheres and the oil-phase material are added into the preparation box 1. The second motor 401 drives the first gear 402, the second gear 403 and the stirring shaft 404 to rotate, and the stirring shaft 404 horizontally stirs the materials. At the same time, the first motor 301 drives the turntable 302 to rotate, the rotation of the turntable 302 drives the swing rod 303 to swing, and the swing of the swing rod 303 drives the guide rod 304 and the box body 305 to move up and down. When the box body 305 moves downward, the materials in the upper layer of the preparation box 1 are extruded downward, so that the upper and lower layer materials are more evenly mixed to form a uniform emulsion.

[0024] The above is only the preferred specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present invention, according to the technical solution of the present invention and its inventive concept, makes equivalent substitutions or changes, and should be covered by the protection scope of the present invention.

Claims

1. A hydrogel microsphere preparation device, characterized in that, It includes a preparation tank (1), a discharge pipe (2), an up-and-down mixing mechanism (3) and a stirring mechanism (4). Three up-and-down mixing mechanisms (3) extending into its interior are installed at the top of the preparation tank (1), and a stirring mechanism (4) extending into its interior is installed at the bottom of the preparation tank (1). The up-and-down mixing mechanism (3) includes: a first motor (301), a turntable (302), a swing rod (303), a guide rod (304), a box body (305), a first pin shaft (306) and a second pin shaft (307). The first motor (301) is fixed on the preparation tank (1), a turntable (302) is fixed on the output shaft of the first motor (301), a swing rod (303) is installed on the turntable (302), the upper end of the swing rod (303) is rotatably connected to the turntable (302) through the first pin shaft (306), the lower end of the swing rod (303) is rotatably connected to the guide rod (304) through the second pin shaft (307), the guide rod (304) extends into the preparation tank (1), the guide rod (304) is slidably connected to the preparation tank (1), and a plurality of box bodies (305) are fixed on the guide rod (304). The stirring mechanism (4) includes: a second motor (401), a first gear (402), a second gear (403) and a stirring shaft (404). The second motor (401) is fixed at the bottom of the preparation tank (1), a first gear (402) is installed on the output shaft of the second motor (401), a second gear (403) meshing with it is installed on one side of the first gear (402), the second gear (403) is installed at the bottom of the stirring shaft (404), and the stirring shaft (404) is rotatably connected to the preparation tank (1).

2. The hydrogel microsphere preparation device according to claim 1, wherein, The three up-and-down mixing mechanisms (3) are evenly distributed in a circular shape with the central axis of the preparation tank (1) as the reference.

3. The hydrogel microsphere preparation device according to claim 1, wherein The preparation tank (1) is made of a transparent material.

4. The hydrogel microsphere preparation device according to claim 1, characterized in that A feeding port (101) is provided at the top of the preparation tank (1), and a plug (102) is detachably installed on the feeding port (101).

5. The hydrogel microsphere preparation device according to claim 1, characterized in that, A discharge pipe (2) is provided at the lower end of the preparation tank (1), and a valve (201) is installed on the discharge pipe (2).