Drug intermediate filtering and mixing device

By designing a drug intermediate filtration and mixing device with rotatable filter cartridge and mixing cartridge, combined with a screw conveyor and drive assembly, the problem of incoordinated operation of the existing device is solved, and efficient filtration and mixing of drug intermediates is achieved, and production efficiency is improved.

CN223158957UActive Publication Date: 2025-07-29GUANGZHOU JIANFENG BIOLOGY PROD CO LTD
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Patent Information

Application Number
CN202422386754.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-29
Publication Date
2025-07-29
Estimated Expiration
2034-09-29

AI Technical Summary

Technical Problem

The operating procedures of existing drug intermediate filtration and mixing devices are not coordinated enough, resulting in inefficient drug production.

Method used

A drug intermediate filtration and mixing device is designed, adopting a rotatable filter cartridge and mixing cartridge structure, combining a screw conveyor and drive assembly to achieve rapid filtration and efficient mixing of drug intermediates.

Benefits of technology

It realizes efficient filtration and mixing of drug intermediates, improves production efficiency, and ensures coordination of filtration and mixing processes.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a medicine intermediate filtering and mixing device which comprises a bottom plate, a first fixing plate and a second fixing plate are oppositely and fixedly connected to the top of the bottom plate, a mixing barrel is arranged between the first fixing plate and the second fixing plate, and a through hole is formed in the middle of the side, close to the second fixing plate, of the mixing barrel. A first rotating shaft fixedly connected with the mixing cylinder is rotationally connected into the first fixing plate, a second rotating shaft penetrating through the through hole and extending into the mixing cylinder is rotationally connected into the second fixing plate, a filter cylinder is further movably connected to the inner side of the through hole, and the side, close to the through hole, of the filter cylinder is of an opening structure; the inner wall of one side of the filter cartridge away from the through hole is fixedly connected with the second rotating shaft. By means of the structure, the whole structure is simple, coordination of the medicine intermediate filtering and mixing process is ensured, efficient mixing and filtering of the medicine intermediate are achieved, and the production efficiency can be improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of medicines, in particular to a filtering and mixing device for pharmaceutical intermediates. Background Technique

[0002] The filtering and mixing device for pharmaceutical intermediates plays an important role in the pharmaceutical industry. With the development of pharmaceutical technology, the requirements for the purity and quality of pharmaceutical intermediates are increasing day by day, which makes efficient filtering and mixing technologies particularly crucial.

[0003] In the prior art, through retrieval, it is found that the Chinese patent discloses a "filtering and mixing device for pharmaceutical intermediates", and its application number is "202321836404.5". The above patent mainly includes a first bottom plate and a second bottom plate. A toothed ring is arranged outside the mixing barrel. An opening groove is arranged outside the mixing barrel. A first groove and a second groove are respectively arranged on both sides of the opening groove. A filter layer is inserted into the first groove. A number of small filter holes are arranged inside the filter layer. A sealing layer is inserted into the second groove. One end of a spring is fixedly connected to a sieve. A partition is arranged inside the sieve. A number of large filter holes are arranged inside the partition. Although the above utility model solves the drawback of uneven mixing caused by simultaneous filtering and discharging through the combined setting of the sealing layer and the filter layer, where the sealing layer plays a sealing role during mixing and the filter layer does not function, and the filter layer plays a role when the sealing layer is removed during filtering. However, after the raw materials are screened by the sieve, they need to be reloaded into the mixing cylinder through the feeding port. After the screened raw materials are loaded into the mixing cylinder, the filter layer and the sealing layer need to be operated to seal the mixing cylinder before the mixing work can be carried out. The overall operation process is not coordinated and efficient enough, which is not conducive to improving the production efficiency of medicines. Therefore, the utility model provides a filtering and mixing device for pharmaceutical intermediates to solve the problems raised in the above background technique. Summary of the Utility Model

[0004] The purpose of the utility model is to provide a filtering and mixing device for pharmaceutical intermediates, with a simple overall structure, ensuring the coordination of the filtering and mixing processes of pharmaceutical intermediates, realizing the efficient mixing and filtering of pharmaceutical intermediates, and being conducive to improving production efficiency.

[0005] To achieve the above purpose, a filtering and mixing device for pharmaceutical intermediates is provided, including a bottom plate. A first fixing plate and a second fixing plate are relatively fixedly connected to the top of the bottom plate. A mixing cylinder is arranged between the first fixing plate and the second fixing plate. A through hole is arranged in the middle of the side of the mixing cylinder close to the second fixing plate. A first rotating shaft fixedly connected to the mixing cylinder is rotatably connected inside the first fixing plate. A second rotating shaft passing through the through hole and extending into the mixing cylinder is rotatably connected inside the second fixing plate. A filter cylinder is also movably connected to the inner side of the through hole. The side of the filter cylinder close to the through hole is of an open structure. The inner wall of the side of the filter cylinder far from the through hole is fixedly connected to the second rotating shaft.

[0006] According to the described drug intermediate filtering and mixing device, a screw conveyor is fixedly connected to the top of the second fixing plate. The screw conveyor is located above the second rotating shaft and extends to the side close to the inside of the filter cylinder.

[0007] According to the described drug intermediate filtering and mixing device, drive components are provided on the sides of the first fixing plate and the second fixing plate away from the mixing cylinder. The drive components include motors, a first pulley and a second pulley fixedly connected to the output shafts of the motors. The motors are fixedly connected to one side of the corresponding first fixing plate or second fixing plate. The second pulley is fixedly connected to the end of the corresponding first rotating shaft or second rotating shaft. The first pulley is connected to the adjacent second pulley by a belt drive.

[0008] According to the described drug intermediate filtering and mixing device, a feeding chute is fixedly connected to one side of the mixing cylinder. A sealing plate is installed on the side of the feeding chute away from the mixing cylinder through four equally spaced and symmetrically arranged connecting components. The connecting components include two adjacent connecting plates and a screw rod threadedly connected inside the two connecting plates. The two connecting plates are respectively fixedly connected to the outer sides of the feeding chute and the sealing plate.

[0009] According to the described drug intermediate filtering and mixing device, a receiving box is provided on the top of the bottom plate and below the side of the filter cylinder opening.

[0010] According to the described drug intermediate filtering and mixing device, the outer diameter of the filter cylinder is slightly smaller than the inner diameter of the through hole.

[0011] The present utility model has the following beneficial effects:

[0012] Compared with the prior art, in this drug intermediate filtering and mixing device, the drug intermediate to be filtered is fed into the filter cylinder through the opening of the filter cylinder. The filter cylinder is set as a rotatable structure so as to realize the rapid filtration of the drug intermediate. The filtered drug intermediate directly falls into the mixing cylinder, and the efficient mixing of the drug intermediate can be realized under the action of the rotatable mixing cylinder. The overall structure is simple, ensuring the coordination of the drug intermediate filtering and mixing processes, realizing the efficient mixing and filtration of the drug intermediate, and being beneficial to improving production efficiency.

[0013] The additional aspects and advantages of the present utility model will be partially given in the following description, partially become obvious from the following description, or be understood through the practice of the present utility model. Description of the Drawings

[0014] The following further illustrates the present utility model in conjunction with the drawings and embodiments;

[0015] Figure 1It is a schematic diagram of the first overall structure of a filter mixing device for a drug intermediate of the present utility model;

[0016] Figure 2 It is a schematic diagram of the second overall structure of a filter mixing device for a drug intermediate of the present utility model;

[0017] Figure 3 It is a schematic diagram of the internal sectional structure of the mixing tank and the filter cartridge of a filter mixing device for a drug intermediate of the present utility model;

[0018] Figure 4 It is a filter mixing device for a drug intermediate of the present utility model Figure 1 The enlarged structure schematic diagram at A.

[0019] Legend:

[0020] 1. Bottom plate; 2. Mixing cylinder; 3. First fixing plate; 4. First rotating shaft; 5. Second fixing plate; 6. Second rotating shaft; 7. Filter cartridge; 8. Screw conveyor; 9. Motor; 10. First pulley; 11. Second pulley; 12. Material receiving box; 13. Feeding chute; 14. Sealing plate; 15. Connecting plate; 16. Screw. Specific implementation mode

[0021] This part will describe in detail the specific embodiments of the present utility model. The preferred embodiments of the present utility model are shown in the drawings. The function of the drawings is to supplement the description of the text part of the specification, enabling people to intuitively and vividly understand each technical feature and the overall technical solution of the present utility model, but it cannot be understood as a limitation on the protection scope of the present utility model.

[0022] Refer to Figures 1-4 As shown in the figure, a filter mixing device for a drug intermediate according to an embodiment of the present utility model includes a bottom plate 1. The first fixing plate 3 and the second fixing plate 5 are fixedly connected to the top of the bottom plate 1 relatively. A mixing cylinder 2 is arranged between the first fixing plate 3 and the second fixing plate 5. A through hole is opened in the middle of the side of the mixing cylinder 2 close to the second fixing plate 5. The first rotating shaft 4 fixedly connected to the mixing cylinder 2 is rotatably connected inside the first fixing plate 3. The second rotating shaft 6 passing through the through hole and extending into the mixing cylinder 2 is rotatably connected inside the second fixing plate 5. The inner side of the through hole is also movably connected with a filter cartridge 7. The outer diameter of the filter cartridge 7 is slightly smaller than the inner diameter of the through hole, so that the filter cartridge 7 can rotate freely in the through hole. One side of the filter cartridge 7 close to the through hole is provided with an open structure, and the inner wall of the side of the filter cartridge 7 far from the through hole is fixedly connected to the second rotating shaft 6.

[0023] The pharmaceutical intermediate to be filtered is fed into the interior of the filter cartridge 7 through the opening of the filter cartridge 7. The filter cartridge 7 is configured to be rotatable, enabling rapid filtration of the pharmaceutical intermediate. The filtered pharmaceutical intermediate directly falls into the interior of the mixing cylinder 2. Under the action of the rotatable mixing cylinder 2, efficient mixing of the pharmaceutical intermediate can be achieved. The overall structure is simple, ensuring the coordination of the filtration and mixing processes of the pharmaceutical intermediate, achieving efficient mixing and filtration of the pharmaceutical intermediate, and facilitating the improvement of production efficiency.

[0024] A screw conveyor 8 is fixedly connected to the top of the second fixing plate 5, which is used to convey the pharmaceutical intermediate into the filter cartridge 7 for filtration. The screw conveyor 8 is located above the second rotating shaft 6 and extends to one side of the filter cartridge 7 close to the interior.

[0025] Drive assemblies are provided on the sides of the first fixing plate 3 and the second fixing plate 5 away from the mixing cylinder 2. The drive assemblies include motors 9, first belt pulleys 10 fixedly connected to the output shafts of the motors 9, and second belt pulleys 11. The motors 9 are fixedly connected to the corresponding sides of the first fixing plate 3 or the second fixing plate 5. The second belt pulleys 11 are fixedly connected to the ends of the corresponding first rotating shaft 4 or the second rotating shaft 6. The first belt pulleys 10 are connected to the adjacent second belt pulleys 11 by belt drives.

[0026] When the motor 9 operates, it drives the first belt pulley 10 to rotate. The rotating first belt pulley 10 synchronously drives the second belt pulley 11 to rotate, thereby enabling the rotation operations of the first rotating shaft 4 and the second rotating shaft 6. The rotation of the first rotating shaft 4 can better drive the rotation of the mixing cylinder 2, enabling the pharmaceutical intermediate inside the mixing cylinder 2 to be fully stirred and mixed. The rotation of the second rotating shaft 6 can better drive the rotation of the filter cartridge 7, and the rotating filter cartridge 7 facilitates the filtration of the pharmaceutical intermediate.

[0027] A discharge chute 13 is fixedly connected to one side of the mixing cylinder 2. A sealing plate 14 is installed on the side of the discharge chute 13 away from the mixing cylinder 2 through four equally spaced and symmetrically arranged connecting components. The connecting components include two adjacent connecting plates 15 and a screw rod 16 threadedly connected inside the two connecting plates 15. The two connecting plates 15 are respectively fixedly connected to the outer sides of the discharge chute 13 and the sealing plate 14.

[0028] Both ends of the discharge chute 13 are open structures. The sealing plate 14 is used to seal the mixing cylinder 2 during the mixing operation. When discharging is required after mixing, the screw rod 16 is operated to separate the sealing plate 14 from the discharge chute 13, and the mixed pharmaceutical intermediate inside the mixing cylinder 2 can be discharged to the outside of the mixing cylinder 2 for collection.

[0029] A receiving box 12 is provided below the top of the bottom plate 1 and on the side of the opening of the filter cartridge 7. The receiving box 12 is used to collect the residual pharmaceutical intermediate in the filter cartridge 7.

[0030] Working principle: The drug intermediate to be filtered is fed into the interior of the filter cartridge 7 through the opening of the filter cartridge 7. The filter cartridge 7 is designed as a rotatable structure, so as to achieve rapid filtration of the drug intermediate. The filtered drug intermediate directly falls into the interior of the mixing cylinder 2. Under the action of the rotatable mixing cylinder 2, efficient mixing of the drug intermediate can be achieved. The overall structure is simple, ensuring the coordination of the filtration and mixing processes of the drug intermediate, realizing the efficient mixing and filtration of the drug intermediate, and being conducive to improving production efficiency.

[0031] The embodiments of the present utility model have been described in detail above in conjunction with the accompanying drawings. However, the present utility model is not limited to the above embodiments. Within the scope of knowledge possessed by those of ordinary skill in the art in the technical field, various changes can also be made without departing from the gist of the present utility model.

Claims

1. A drug intermediate filtration and mixing device, characterized in that, It includes a bottom plate (1), on the top of which are fixedly connected with a first fixing plate (3) and a second fixing plate (5) relatively. A mixing cylinder (2) is arranged between the first fixing plate (3) and the second fixing plate (5). A through hole is opened in the middle of the side of the mixing cylinder (2) close to the second fixing plate (5). A first rotating shaft (4) fixedly connected with the mixing cylinder (2) is rotatably connected inside the first fixing plate (3). A second rotating shaft (6) passing through the through hole and extending into the mixing cylinder (2) is rotatably connected inside the second fixing plate (5). A filter cylinder (7) is also movably connected to the inner side of the through hole. The side of the filter cylinder (7) close to the through hole is of an open structure. The inner wall of the side of the filter cylinder (7) far from the through hole is fixedly connected with the second rotating shaft (6).

2. The filtering and mixing device for a pharmaceutical intermediate according to claim 1, characterized in that, A screw conveyor (8) is fixedly connected to the top of the second fixing plate (5). The screw conveyor (8) is located above the second rotating shaft (6) and extends to the side close to the inside of the filter cylinder (7).

3. The filtering and mixing device for a pharmaceutical intermediate according to claim 2, characterized in that, Driving components are arranged on the sides of the first fixing plate (3) and the second fixing plate (5) far from the mixing cylinder (2). The driving components include a motor (9), a first belt pulley (10) and a second belt pulley (11) fixedly connected to the output shaft of the motor (9). The motor (9) is fixedly connected to the side of the corresponding first fixing plate (3) or second fixing plate (5). The second belt pulley (11) is fixedly connected to the end of the corresponding first rotating shaft (4) or second rotating shaft (6). The first belt pulley (10) is connected to the adjacent second belt pulley (11) by a belt for transmission connection.

4. A drug intermediate filtration and mixing device according to claim 3, characterized in that, A feeding chute (13) is fixedly connected to one side of the mixing cylinder (2). A sealing plate (14) is installed on the side of the feeding chute (13) far from the mixing cylinder (2) through four equally spaced and symmetrically arranged connecting components. The connecting components include two adjacent connecting plates (15) and a screw rod (16) threadedly connected inside the two connecting plates (15). The two connecting plates (15) are respectively fixedly connected to the outer sides of the feeding chute (13) and the sealing plate (14).

5. A filtering and mixing device for a pharmaceutical intermediate according to claim 4, characterized in that, A receiving box (12) is arranged on the top of the bottom plate (1) and below the open side of the filter cylinder (7).

6. A drug intermediate filtration and mixing device according to claim 5, characterized in that, The outer diameter of the filter cylinder (7) is slightly smaller than the inner diameter of the through hole.

Citation Information

Patent Citations

  • Drug intermediate filtering and mixing device

    CN220294595U