Powder removing device for reagent bottle opening

Abstract

The utility model discloses a reagent bottle opening powder removing device which comprises a static electricity eliminating mechanism and a powder removing mechanism, and the static electricity eliminating mechanism is arranged at a powder outlet of a racking machine and used for generating electric ions to eliminate static electricity; and the powder removing mechanism is arranged at the downstream of the static electricity eliminating mechanism and is used for blowing airflow to the reagent bottle opening. According to the powder removing device for the reagent bottle opening, static electricity can be eliminated, adhesion of medicine powder can be reduced, and meanwhile the medicine powder on the bottle opening can be removed more easily; and the powder removing mechanism is arranged, airflow is blown out of the reagent bottle opening after static electricity is eliminated, so that residual powder of the bottle opening is fully removed, the plugging sealing performance after medicine subpackaging is effectively guaranteed, and the production quality of medicine is improved.

Description

Technical Field

[0001] This application relates to the technical field of filling equipment, and particularly to a powder removing device for reagent bottle mouths. Background Art

[0002] Powder injection agents are classified into sterile powder dispensing preparations and freeze-dried powder injection preparations according to the preparation principle. For sterile powder dispensing drugs (such as ceftriaxone sodium for injection, ceftazidime for injection, etc.), the commonly used screw filling machines in the industry are used to fill them into injection bottles. Injection bottles are made of borosilicate glass or soda-lime glass by tube-making (molding), and are sealed with rubber stoppers and aluminum-plastic combination caps. Because penicillin was mostly used to hold it in the early days, it is also called a vial.

[0003] However, during the filling production process, a small amount of drug powder may be scattered on the bottle mouth, which will cause the subsequent rubber stopper to be not tightly sealed with the bottle mouth. Oxygen, moisture, etc. in the air come into contact with the sterile powder, which is likely to cause changes in the physical and chemical properties of the drug, quality problems in sterile drugs, and serious adverse reactions after use, posing a hazard to life, health and safety.

[0004] Therefore, how to reduce the residue of drug powder at the bottle mouth is a technical problem that needs to be solved urgently by those skilled in the art. Content of the Utility Model

[0005] To solve the above technical problems, the purpose of the present utility model is to provide a powder removing device for reagent bottle mouths; the powder removing device for reagent bottle mouths provided by this application can eliminate static electricity to reduce the adhesion of drug powder, and at the same time make the drug powder on the bottle mouth easier to be removed; and a powder removing mechanism is provided to blow out air flow to the reagent bottle mouth after eliminating static electricity, so as to fully remove the residual powder at the bottle mouth, effectively ensure the plugging tightness after drug filling, and improve the production quality of drugs.

[0006] The technical solution provided by the present utility model is as follows:

[0007] A powder removing device for reagent bottle mouths includes a static electricity eliminating mechanism and a powder removing mechanism.

[0008] The static electricity eliminating mechanism is arranged at the powder outlet of the filling machine and is used to emit ions to eliminate static electricity.

[0009] The powder removing mechanism is arranged downstream of the static electricity eliminating mechanism and is used to blow out air flow to the reagent bottle mouth.

[0010] Preferably, the static electricity eliminating mechanism includes an ion bar and a first base.

[0011] The ion bar is installed on the first base, and the electrode of the ion bar faces the powder outlet of the filling machine.

[0012] Preferably, the static electricity eliminating mechanism further includes a first adjusting mechanism, and the first adjusting mechanism includes a first adjusting rod and a first locking member.

[0013] The first base is provided with a vertical first slot, and a first threaded hole is also opened on the side of the first slot;

[0014] The first adjusting rod is slidably inserted into the first slot, and the first locking member is in threaded cooperation with the first threaded hole to lock or loosen the first adjusting rod;

[0015] The ion rod is fixedly connected to one end of the first adjusting rod away from the first base.

[0016] Preferably, the ion rod is provided with a plurality of electrodes.

[0017] Preferably, the dust removing mechanism includes a high-pressure air source, a blowing component and a valve,

[0018] The blowing component is provided with an air inlet and an air outlet, and an air flow channel is formed between the air inlet and the air outlet;

[0019] The air inlet is communicated with the high-pressure air source through a pipeline, and a valve is arranged on the pipeline;

[0020] The air outlet is annular, located at the bottom of the blowing component, and the connection between the air flow channel and the air outlet forms an angle with the vertical direction.

[0021] Preferably, the blowing component includes an air cap and an air core,

[0022] The air cap is formed by a top plate and a cylindrical side wall to enclose a cavity with a hollow interior and an open bottom;

[0023] The air core includes a vertical section and an expansion section. The vertical section is erected in the air cap, and the top end is connected to the top plate of the air cap, and the bottom end is connected to the expansion section; the diameter of the expansion section gradually increases from top to bottom, and the bottom of the expansion section and the bottom opening of the air cap together form the air outlet;

[0024] The bottom opening of the air cap is provided with an inclined edge, and the slope of the inclined edge is smaller than the slope of the outer wall of the expansion section;

[0025] The air inlet is arranged on the top plate or the side wall of the air cap.

[0026] Preferably, a flange is formed inwardly on a part of the side wall of the air cap to narrow the corresponding air flow channel.

[0027] Preferably, the dust removing mechanism further includes a sensor and a controller. The sensor is arranged below the blowing component; the controller receives the signal of the sensor and controls the opening of the valve.

[0028] Preferably, the dust removing mechanism further includes a second adjusting mechanism. The second adjusting mechanism includes a second adjusting rod, a second locking member and a second fixing seat,

[0029] The second fixing seat is provided with a vertical second slot, and a second threaded hole is also opened on the side of the second slot;

[0030] The second adjusting rod is slidably inserted into the second slotted opening, and the second locking member is in threaded fit with the second threaded hole to lock or loosen the second adjusting rod;

[0031] The air blowing component is fixedly connected to one end of the second adjusting rod away from the second fixing seat.

[0032] Preferably, a protective gas is stored in the high-pressure gas source; and / or,

[0033] A sterilizing filter is further provided on the pipeline.

[0034] The applicant has found in practice that blowing air at the reagent bottle mouth cannot effectively remove the residual powder, and there is still a risk that the rubber stopper is not tightly sealed with the bottle mouth, thus affecting the product quality. After analysis, it is found that during the aseptic powder drug dispensing process, static electricity is generated by the flowing friction of the powder, causing the powder to be adsorbed on the edge of the powder outlet of the filling machine or on the reagent bottle mouth due to static electricity. Moreover, when the reagent bottle is moved under the powder outlet of the filling machine for powder dispensing, the powder accumulated at the powder outlet of the filling machine is affected by the vibration of the equipment operation, resulting in the accumulated powder being scattered on the bottle mouth.

[0035] In view of the above problems, the present application provides a powder removing device for a reagent bottle mouth, including an electrostatic elimination mechanism and a powder removing mechanism. The electrostatic elimination mechanism is arranged at the powder outlet of the filling machine and is used to emit ions to eliminate the static electricity generated during the flowing friction of the powder, so that the powder cannot or is minimized to accumulate at the powder outlet of the filling machine, thereby reducing the problem of powder scattering at the bottle mouth during the powder dispensing process; meanwhile, the static electricity of the powder adhered to the bottle mouth is eliminated, making the powder on the bottle mouth easier to be removed. At this time, there may still be a small amount of dust falling on the reagent bottle mouth. In order to minimize the powder residue at the bottle mouth to the greatest extent, the present application also blows air at the reagent bottle mouth after static electricity elimination through the powder removing mechanism arranged downstream of the electrostatic elimination mechanism, so as to fully remove the residual powder at the bottle mouth, effectively ensure the plugging tightness after drug dispensing, and improve the production quality of the drug. Description of the Drawings

[0036] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the drawings in the following description are only some embodiments recorded in the present application. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0037] Figure 1 It is a schematic structural diagram of the powder removing device for a reagent bottle mouth in an embodiment of the present utility model;

[0038] Figure 2This is a partially enlarged schematic view of the powder removal device for the reagent bottle mouth in the embodiment of the present utility model;

[0039] Reference numerals: 1 - ion rod; 11 - electrode; 2 - first base; 21 - first slot; 3 - first adjustment mechanism; 31 - first adjustment rod; 32 - first locking member; 4 - high-pressure gas source; 5 - blowing component; 51 - air inlet; 52 - air outlet; 53 - air cap; 531 - flange; 532 - bevel edge; 54 - air core; 541 - vertical section; 542 - expansion section; 6 - valve; 7 - sensor; 8 - second adjustment mechanism; 81 - second adjustment rod; 82 - second locking member; 83 - second fixing base; 831 - second slot; 9 - sterilizing filter; a - powder outlet of the powder filling machine; b - reagent bottle. Detailed implementation manners

[0040] In order to enable those skilled in the art to better understand the technical solutions in this application, the technical solutions in the embodiments of this application will be clearly and completely described below. Obviously, the described embodiments are only a part of the embodiments of this application, rather than all the embodiments. Based on the embodiments in this application, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of this application.

[0041] It should be noted that when an element is referred to as being "fixed to" or "disposed on" another element, it can be directly on the other element or indirectly disposed on the other element; when an element is referred to as being "connected to" another element, it can be directly connected to the other element or indirectly connected to the other element.

[0042] It should be understood that the orientation or positional relationship indicated by the terms "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing this application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as a limitation to this application.

[0043] In addition, the terms "first" and "second" are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include one or more of such features. In the description of this application, the meanings of "a plurality" and "several" are two or more, unless otherwise specifically defined.

[0044] It should be noted that the structures, ratios, sizes, etc. shown in the attached drawings of this specification are only used to cooperate with the content disclosed in the specification for those familiar with this technology to understand and read, and are not used to limit the implementation conditions of this application. Therefore, they do not have substantial technical significance. Any modification of the structure, change in the proportional relationship, or adjustment of the size, without affecting the efficacy that this application can produce and the purpose that can be achieved, should still fall within the scope covered by the technical content disclosed in this application.

[0045] As shown in the figure, an embodiment of the present utility model provides a powder removing device for the reagent bottle mouth, including an electrostatic elimination mechanism and a powder removing mechanism.

[0046] The electrostatic elimination mechanism is arranged at the powder outlet of the powder filling machine and is used to emit ions to eliminate static electricity.

[0047] The powder removing mechanism is arranged downstream of the electrostatic elimination mechanism and is used to blow air flow towards the reagent bottle mouth.

[0048] The applicant found in practice that blowing air at the reagent bottle mouth cannot effectively remove the residual powder, and there is still a risk that the rubber stopper is not tightly sealed with the bottle mouth, thus affecting the product quality. After analysis, it is found that during the process of aseptic powder drug filling, static electricity is generated due to the flow friction of the drug powder, resulting in the drug powder being adsorbed on the edge of the powder outlet of the powder filling machine or adsorbed on the reagent bottle mouth by static electricity. Moreover, when the reagent bottle moves to the lower part of the powder outlet of the powder filling machine for powder filling, the accumulated powder at the powder outlet of the powder filling machine is affected by the vibration of the equipment operation, which will cause the accumulated powder to fall on the bottle mouth.

[0049] To address the above problems, this application provides a powder removing device for the reagent bottle mouth, including an electrostatic elimination mechanism and a powder removing mechanism. The electrostatic elimination mechanism is arranged at the powder outlet of the powder filling machine and is used to emit ions to eliminate the static electricity generated during the flow friction of the drug powder, so that the drug powder cannot or accumulates as little as possible at the powder outlet of the powder filling machine, thereby reducing the problem of powder scattering at the bottle mouth during the powder filling process. At the same time, the static electricity of the drug powder adhering to the bottle mouth is eliminated, making the drug powder on the bottle mouth easier to be removed. At this time, there may still be a small amount of dust falling on the reagent bottle mouth. In order to minimize the residual powder at the bottle mouth to the greatest extent, this application also uses a powder removing mechanism arranged downstream of the electrostatic elimination mechanism to blow air flow towards the reagent bottle mouth after eliminating static electricity, so as to fully remove the residual powder at the bottle mouth, effectively ensure the plugging tightness after drug filling, and improve the production quality of drugs.

[0050] The powder removing device for the reagent bottle mouth provided by this application is installed on the powder filling machine and uses the conveying devices such as the reagent bottle conveyor belt of the powder filling machine itself, so that the reagent bottle after filling powder and eliminating static electricity at the filling port is conveyed to the downstream for capping or other processing after being removed of powder by the powder removing mechanism.

[0051] Preferably, the electrostatic elimination mechanism includes an ion bar 1 and a first base 2.

[0052] The ion bar 1 is installed on the first base 2, and the electrode 11 of the ion bar 1 faces the powder outlet of the powder filling machine.

[0053] Preferably, the static electricity eliminating mechanism includes an ion bar 1 and a first base 2. The ion bar 1 is installed on the first base 2, and the electrode 11 of the ion bar 1 faces the powder outlet of the powder filling machine. After the ion bar 1 is powered on, the ion bar electrode 11 will emit charged ions towards the powder outlet of the powder filling machine and the reagent bottle below it. The emitted ions will contact the powder outlet of the powder filling machine and the reagent bottle, and neutralize the charges carried here, reducing the firmness of the powder adsorption here, thereby avoiding or reducing the problem of powder aggregation and powder scattering at the powder outlet of the powder filling machine, and also reducing the aggregation of powder at the reagent bottle mouth.

[0054] Preferably, the static electricity eliminating mechanism further includes a first adjusting mechanism 3. The first adjusting mechanism 3 includes a first adjusting rod 31 and a first locking member 32.

[0055] The first base 2 is provided with a vertical first slot 21, and a first threaded hole is also opened on the side of the first slot 21.

[0056] The first adjusting rod 31 is slidably inserted into the first slot 21, and the first locking member 32 is in threaded cooperation with the first threaded hole to lock or loosen the first adjusting rod 31.

[0057] The ion bar 1 is fixedly connected to one end of the first adjusting rod 31 away from the first base 2.

[0058] Preferably, the static electricity eliminating mechanism further includes a first adjusting mechanism 3 for adjusting the height of the ion bar 1 relative to the first base 2, so that the ion bar 1 can be adjusted according to the height of reagent bottles of different specifications to meet the anti-static requirements of reagent bottles of different specifications.

[0059] Specifically, the first adjusting mechanism 3 includes a first adjusting rod 31 and a first locking member 32. The first base 2 is provided with a vertical first slot 21, and a first threaded hole is also opened on the side of the first slot 21. The first adjusting rod 31 is slidably inserted into the first slot 21, and the first locking member 32 is in threaded cooperation with the first threaded hole to lock or loosen the first adjusting rod 31. When adjustment is needed, loosen the first locking member 32 to make the first adjusting rod 31 slide up and down along the first slot 21 until the ion bar 1 fixedly connected to one end of the first adjusting rod 31 away from the first base 2 reaches the required height, and then lock the first locking member 32 to fix the position of the first adjusting rod 31. The adjustment is convenient and has good durability.

[0060] The first locking member 32 preferably uses a bolt.

[0061] Preferably, the ion bar 1 is provided with a plurality of electrodes 11.

[0062] Preferably, the ion bar 1 is provided with a plurality of electrodes 11, and more charged ions are generated within a certain period of time, resulting in higher efficiency in eliminating static electricity.

[0063] The ion bar is a mature and purchasable component known in the art, and the number of electrodes on the ion bar can also be obtained by selecting different models of ion bars according to needs.

[0064] Preferably, the powder removal mechanism includes a high-pressure gas source 4, a blowing component 5, and a valve 6.

[0065] The blowing component 5 is provided with an air inlet 51 and an air outlet 52, and an air flow channel is formed between the air inlet 51 and the air outlet 52.

[0066] The air inlet 51 is connected to the high-pressure gas source 4 through a pipeline, and a valve 6 is provided on the pipeline.

[0067] The air outlet 52 is annular and is located at the bottom of the blowing component 5, and the connection between the air flow channel and the air outlet 52 forms an angle with the vertical direction.

[0068] Preferably, the powder removal mechanism includes a high-pressure gas source 4, a blowing component 5, and a valve 6. The blowing component 5 is provided with an air inlet 51 and an air outlet 52, and an air flow channel is formed between the air inlet 51 and the air outlet 52. The air inlet 51 is connected to the high-pressure gas source 4 through a pipeline, and a valve 6 is provided on the pipeline. The air outlet 52 is annular and is located at the bottom of the blowing component 5. After the valve 6 is opened, the high-pressure gas provided by the high-pressure gas source 4 can quickly enter the air inlet 51 through the pipeline, flow through the air flow channel and be ejected from the air outlet 52 at the bottom to blow the powder on the reagent bottle mouth.

[0069] Since the air outlet 52 is annular and corresponds to the annular bottle mouth, it can remove the trace powder on the bottle mouth and ensure the sealing performance after encapsulation. Moreover, compared with the air flow blowing directly downward at the bottle mouth, the connection between the air flow channel and the air outlet 52 also forms an angle with the vertical direction, so the ejected air flow is also inclined and not vertically downward, which can avoid blowing the powder in the bottle out during purging and affecting the accuracy of the product filling volume.

[0070] Preferably, the blowing component 5 includes an air cap 53 and an air core 54.

[0071] The air cap 53 is formed by a top plate and a cylindrical side wall to enclose a cavity with a hollow interior and an open bottom.

[0072] The air core 54 includes a vertical section 541 and an expansion section 542. The vertical section 541 is erected in the air cap 53, and the top end is connected to the top plate of the air cap 53, and the bottom end is connected to the expansion section 542. The diameter of the expansion section 542 gradually increases from top to bottom, and the bottom of the expansion section 542 and the open bottom of the air cap 53 together form the air outlet 52.

[0073] The bottom opening of the air cap 53 is provided with an inclined edge 532, and the slope of the inclined edge 532 is smaller than the slope of the outer wall of the expansion section 542;

[0074] The air inlet 51 is arranged on the top plate or the side wall of the air cap 53.

[0075] Preferably, the blowing component 5 includes an air cap 53 and an air core 54. The air cap 53 is formed by a top plate and a cylindrical side wall to enclose a shape with a hollow inner cavity and an open bottom; the air core 54 is fixed in the inner cavity of the air cap 53, and the air core 54 includes a vertical section 541 and an expansion section 542. The vertical section 541 is erected in the air cap 53, with the top end connected to the top plate of the air cap 53 and the bottom end connected to the expansion section 542; the diameter of the expansion section 542 gradually increases from top to bottom, and the bottom of the expansion section 542 and the bottom opening of the air cap 53 jointly form an air outlet 52; then the air flow channel is jointly enclosed by the inner cavity of the air cap 53 and the outer wall of the air core 54. High-pressure gas enters from the air inlet 51 on the top plate or the side wall of the air cap 53 and flows along the air flow channel, and finally is ejected from the part of the bottom opening of the air cap 53 that is not blocked by the air core 54, and this part is the annular air outlet 52.

[0076] This application defines that the bottom opening of the air cap 53 is provided with an inclined edge 532, and the slope of the inclined edge 532 is smaller than the slope of the outer wall of the expansion section 542. Due to the different degrees of inclination of the two, the air flow channel between the inclined edge 532 and the outer wall of the expansion section 542 is not only inclined, but also gradually becomes larger from top to bottom, which has a better guiding effect on the air flow. It can not only prevent the air flow from blowing into the bottle, avoiding the air flow from blowing out the medicinal powder in the bottle during purging and affecting the product filling amount; but also ensure that the blowing area covers the entire annular end face of the bottle mouth, avoiding the situation that a part of the bottle mouth is not purged.

[0077] Preferably, a flange 531 is formed inwardly on a part of the side wall of the air cap 53 to narrow the corresponding air flow channel.

[0078] More preferably, a flange 531 is formed inwardly on a part of the side wall of the air cap 53 to narrow the corresponding air flow channel, thereby forming a pressurized air flow channel section. When the gas flows through, the air flow speed and pressure can be increased, and the air powder removal ability can be improved.

[0079] Preferably, the powder removal mechanism further includes a sensor 7 and a controller. The sensor 7 is arranged below the blowing component 5; the controller receives the signal of the sensor 7 and controls the opening of the valve 6.

[0080] Preferably, the powder removing mechanism further includes a sensor 7 and a controller. The sensor 7 is arranged below the air blowing component 5. The controller receives the signal from the sensor 7 and controls the valve 6 to open for a predetermined time. Then, when a reagent bottle reaches below the powder removing mechanism, high-pressure gas blowing is performed for powder removal once. After the operation is completed, the reagent bottle is moved away. When the next reagent bottle moves to this position, the next high-pressure gas blowing for powder removal is performed. The degree of automation is high, and the high-pressure air flow can accurately blow the bottle mouth.

[0081] The controller is a PLC (Programmable Logic Controller) used to control the operation of the filling machine, which is a mature component that can be purchased in the market. For example, a controller with model S71200 1214C can be used.

[0082] The valve 6 is preferably a solenoid valve. The sensor 7 is preferably a photoelectric sensor. The position where the sensor 7 is arranged can be the bottle mouth of the reagent bottle or the bottle body of the reagent bottle. Through debugging, it can be ensured that when the sensor 7 senses the reagent bottle, the bottle mouth of the reagent bottle is exactly below the powder removing mechanism.

[0083] Preferably, the powder removing mechanism further includes a second adjusting mechanism 8. The second adjusting mechanism 8 includes a second adjusting rod 81, a second locking member 82 and a second fixing seat 83.

[0084] The second fixing seat 83 is provided with a vertical second slot 831, and a second threaded hole is also opened on the side of the second slot 831.

[0085] The second adjusting rod 81 is slidably inserted into the second slot 831. The second locking member 82 is in threaded cooperation with the second threaded hole to lock or loosen the second adjusting rod 81.

[0086] The air blowing component 5 is fixedly connected to one end of the second adjusting rod 81 away from the second fixing seat 83.

[0087] Preferably, the powder removing mechanism further includes a second adjusting mechanism 8, so that the air blowing component 5 can adjust its own height according to the height of reagent bottles of different specifications to meet the powder removing requirements of reagent bottles of different specifications.

[0088] Specifically, the second adjusting mechanism 8 includes a second adjusting rod 81, a second locking member 82 and a second fixing member 83. The second base 2 is provided with a vertical second slot 831, and a second threaded hole is also opened on the side of the second slot 831. The second adjusting rod 81 is slidably inserted into the second slot 831. The second locking member 82 is in threaded cooperation with the second threaded hole to lock or loosen the second adjusting rod 81. When adjustment is needed, loosen the second locking member 82 to make the second adjusting rod 81 slide up and down along the second slot 831 until the air blowing component 5 fixedly connected to one end of the second adjusting rod 81 away from the second fixing seat 83 reaches the required height, and then lock the second locking member 82 to fix the position of the second adjusting rod 81. The adjustment is convenient and the durability is good.

[0089] The second locking member 82 preferably uses a bolt, and the second threaded hole is provided with a matching thread.

[0090] Preferably, a protective gas is stored in the high-pressure gas source 4; and / or,

[0091] A sterilizing filter 9 is also provided on the pipeline.

[0092] Preferably, a protective gas (such as nitrogen, helium, etc.) is stored in the high-pressure gas source 4 to avoid the influence of oxygen on the quality of the medicinal powder.

[0093] Preferably, a sterilizing filter 9 is also provided on the pipeline to sterilize the high-pressure gas and avoid affecting the quality of the medicinal powder.

[0094] The above description of the disclosed embodiments enables those skilled in the art to implement or use the present invention. Various modifications to these embodiments will be obvious to those skilled in the art, and the general principles defined herein can be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention will not be limited to these embodiments shown herein, but rather to the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A reagent bottle mouth powder removal device, characterized in that, It includes an electrostatic elimination mechanism and a powder removal mechanism. The electrostatic elimination mechanism is arranged at the powder outlet of the filling machine and is used to emit ions to eliminate static electricity. The powder removal mechanism is arranged downstream of the electrostatic elimination mechanism and is used to blow air flow towards the reagent bottle mouth.

2. The reagent bottle mouth powder removal device according to claim 1, characterized in that The electrostatic elimination mechanism includes an ion bar (1) and a first base (2). The ion bar (1) is installed on the first base (2), and the electrode (11) of the ion bar (1) faces the powder outlet of the filling machine.

3. The reagent bottle mouth powder removal device according to claim 2, wherein, The electrostatic elimination mechanism further includes a first adjustment mechanism (3), and the first adjustment mechanism (3) includes a first adjustment rod (31) and a first locking member (32). The first base (2) is provided with a vertical first slot (21), and a first threaded hole is also opened on the side of the first slot (21). The first adjustment rod (31) is slidably inserted into the first slot (21), and the first locking member (32) is in threaded cooperation with the first threaded hole to lock or loosen the first adjustment rod (31). The ion bar (1) is fixedly connected to the end of the first adjustment rod (31) away from the first base (2).

4. The reagent bottle mouth powder removal device according to claim 2, wherein The ion bar (1) is provided with a plurality of electrodes (11).

5. The reagent bottle mouth powder removal device according to any one of claims 1-4, characterized in that, The powder removal mechanism includes a high-pressure air source (4), a blowing component (5) and a valve (6). The blowing component (5) is provided with an air inlet (51) and an air outlet (52), and an air flow channel is formed between the air inlet (51) and the air outlet (52). The air inlet (51) is connected to the high-pressure air source (4) through a pipeline, and a valve (6) is arranged on the pipeline. The air outlet (52) is annular and is located at the bottom of the blowing component (5), and the connection between the air flow channel and the air outlet (52) forms an angle with the vertical direction.

6. The reagent bottle mouth powder removal device according to claim 5, wherein, The blowing component (5) includes an air cap (53) and an air core (54). The air cap (53) is formed by a top plate and a cylindrical side wall to enclose a cavity with a hollow interior and an open bottom. The air core (54) includes a vertical section (541) and an expansion section (542). The vertical section (541) is erected in the air cap (53), and the top end is connected to the top plate of the air cap (53), and the bottom end is connected to the expansion section (542). The diameter of the expansion section (542) gradually increases from top to bottom, and the bottom of the expansion section (542) and the bottom opening of the air cap (53) together form the air outlet (52). The bottom opening of the air cap (53) is provided with an inclined edge (532), and the slope of the inclined edge (532) is smaller than the slope of the outer wall of the expansion section (542). The air inlet (51) is arranged on the top plate or the side wall of the air cap (53).

7. The reagent bottle mouth powder removal device according to claim 6, characterized in that, A flange (531) is formed inwardly on a part of the side wall of the air cap (53) to narrow the corresponding air flow channel.

8. The reagent bottle mouth powder removal device according to claim 5, characterized in that, The powder removal mechanism further includes a sensor (7) and a controller. The sensor (7) is arranged below the blowing component (5). The controller receives the signal of the sensor (7) and controls the opening of the valve (6).

9. The reagent bottle mouth powder removal device according to claim 5, wherein, The powder removal mechanism further includes a second adjustment mechanism (8), and the second adjustment mechanism (8) includes a second adjustment rod (81), a second locking member (82) and a second fixing seat (83). The second fixing seat (83) is provided with a vertical second slot (831), and a second threaded hole is also opened on the side of the second slot (831). The second adjusting rod (81) is slidably inserted into the second slot (831), and the second locking member (82) is in threaded fit with the second threaded hole to lock or loosen the second adjusting rod (81); The air blowing component (5) is fixedly connected to one end of the second adjusting rod (81) away from the second fixing seat (83).

10. The reagent bottle mouth powder removal device according to claim 5, characterized in that, The high-pressure gas source (4) stores a protective gas; and / or, A sterilizing filter (9) is further provided on the pipeline.

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