Falling film absorption device for flucytosine
By setting grooves and spoiler rods in the flucytosine falling film absorption device, the solution flow rate is controlled and the liquid film downflow and vortex flow is formed, the problem of low absorption efficiency in the existing device is solved, and more efficient flucytosine absorption is achieved.
Patent Information
- Application Number
- CN202422273927.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-18
- Publication Date
- 2025-08-01
- Estimated Expiration
- 2034-09-18
AI Technical Summary
During the chlorination of flucytosine, the existing falling film absorption device is prone to pass through the tube when the solution flows are large, resulting in a decrease in absorption efficiency and the rapid gas penetration rate affecting the absorption efficiency.
A falling film absorption device for flucytosine is designed, including a main mechanism and a spoiler mechanism. The solution flow is controlled by setting grooves and through holes on the top plate, and a gas supply member and a spoiler rod are provided in the tube body to form a liquid film downflow and vortex to improve absorption efficiency.
By controlling the solution flow rate and spoiler, the absorption efficiency of flucytosine is improved, ensuring that the solution forms a stable liquid film on the tube wall, enhancing the contact effect between gas and liquid, and improving the absorption efficiency.
Smart Images

Figure CN223170668U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of flucytosine production, in particular to a falling film absorption device for flucytosine. Background Technique
[0002] Flucytosine is an antifungal drug, and its mechanism of action is that the drug enters the cell through the permease system of the fungal cell and is converted into fluorouracil. It replaces uracil and enters the deoxyribonucleic acid of the fungus, thereby blocking the synthesis of nucleic acids. Due to the good clinical effect of flucytosine in treating fungi, it has attracted much attention from major pharmaceutical companies at present.
[0003] Currently, the hydrogen chloride gas absorption in the chlorination process of flucytosine generally adopts a falling film absorption tower. However, the existing falling film absorption device mainly has the following disadvantages in the process of use: when the solution flow rate is large, it will pass through the pipe, resulting in no chance to form a liquid film flowing down on the pipe wall, which will greatly reduce the absorption efficiency. At the same time, the gas passing speed through the pipe is too fast, further affecting the absorption efficiency. Therefore, there is room for improvement. Content of the Utility Model
[0004] The utility model aims to solve one of the technical problems existing in the prior art or related technologies.
[0005] For this reason, the technical solution adopted by the utility model is as follows: a falling film absorption device for flucytosine, comprising: a main body mechanism and a flow disturbing mechanism. The main body mechanism includes a shell, a top plate fixed on the inner wall of the shell, a bottom plate fixed on the inner wall of the shell, a plurality of pipe bodies annularly and arrayedly installed between the top plate and the bottom plate, a box body fixed on the inner wall of the shell, a plurality of air supply members annularly and arrayedly installed at the bottom end of the box body and extending into the pipe bodies, a liquid inlet member fixed on the outer side of the box body and extending out of the shell, an air inlet pipe installed at the top end of the box body and extending out of the shell, and a discharge member installed at the bottom end of the shell.
[0006] The air supply member includes a conical shell fixed at the bottom end of the box body and communicating with the inner cavity of the box body, a transmission pipe fixed at the bottom end of the conical shell and passing through the top plate and extending into the inner cavity of the pipe body, and an arc-shaped shell fixedly sleeved on the outer side of the transmission pipe. The bottom diameter of the arc-shaped shell is slightly smaller than the diameter of the pipe body.
[0007] The flow disturbing mechanism includes a plurality of brackets fixed on the inner wall of the shell and a plurality of flow disturbing rods annularly and arrayedly installed on the brackets and extending into the inner cavity of the pipe body.
[0008] The utility model can be further configured in a preferred example as follows: the flow disturbing rod includes a round rod with the bottom end fixed on the bracket and the top end extending into the inner cavity of the pipe body, and spheres arrayedly fixed on the round rod.
[0009] In a preferred embodiment of the present utility model, it can be further configured that: the top end of the top plate is provided with grooves in an annular array, and the inner bottom wall of the grooves is provided with first through holes in an annular array, and the first through holes communicate the grooves with the inner cavity of the pipe body.
[0010] In a preferred embodiment of the present utility model, it can be further configured that: the liquid inlet member includes an annular empty pipe fixed on the outer side of the box body and a liquid inlet pipe with one end communicating with the annular empty pipe and the other end extending out of the shell, and the bottom end of the annular empty pipe is provided with a plurality of second through holes in an annular array.
[0011] In a preferred embodiment of the present utility model, it can be further configured that: the discharge member includes a liquid discharge pipe installed at the bottom end of the shell and communicating with the inner cavity of the shell and an exhaust pipe installed on one side of the shell and communicating with the inner cavity of the shell.
[0012] By adopting the above technical solutions, the beneficial effects obtained by the present utility model are as follows:
[0013] 1. In the present utility model, a top plate and a bottom plate are fixed on the inner wall of the shell, and a plurality of pipe bodies are arranged in an annular array between the top plate and the bottom plate. The top end of the top plate is provided with grooves in an annular array, and the inner bottom wall of the grooves is provided with first through holes in an annular array. The first through holes communicate the grooves with the inner cavity of the pipe body. Through the setting of the first through holes, the flow rate of the solution entering the pipe body is controlled. An air inlet pipe extending out of the shell is fixed at the top end of the shell. The bottom end of the air inlet pipe is provided with a box body. A plurality of air supply members are arranged in an annular array at the bottom end of the box body. Each air supply member extends into the inner cavity of the corresponding pipe body. At the same time, a liquid inlet member is arranged outside the box body. In addition, the air supply member is composed of a conical shell, a transmission pipe and an arc-shaped shell. Through the above settings, when the solution falls above the top plate through the liquid inlet member, it passes through the top plate and enters the pipe body. At this time, the solution can flow along the surface of the arc-shaped shell and flow to the inner wall of the pipe body to continue flowing after flowing through the bottom edge of the arc-shaped shell, forming a liquid film flowing down on the inner wall of the pipe body, thereby improving the absorption efficiency and increasing the practicability.
[0014] 2. In the present utility model, a plurality of brackets are fixed on the inner wall of the shell, and spoiler rods are arranged in an annular array on the brackets. Each spoiler rod extends into the inner cavity of the corresponding pipe body. Through the action of the spoiler rods, when the gas enters the pipe body, the air flow can be disturbed to continuously generate eddy currents. The inertial force of the eddy currents is used to gradually reduce the gas flow rate, so that the gas can be fully absorbed by the liquid film, further increasing the absorption efficiency and improving the practical performance. BRIEF DESCRIPTION OF THE DRAWINGS
[0015] Figure 1 is a schematic structural diagram of the present utility model;
[0016] Figure 2 is of the present utility model Figure 1Enlarged schematic view of part A
[0017] Figure 3 Schematic diagram of the flow disturbing mechanism of the present utility model
[0018] Figure 4 Schematic diagram of the top plate structure of the present utility model
[0019] Figure 5 Schematic sectional structure diagram of the top plate of the present utility model
[0020] Reference numerals:
[0021] 100, main body mechanism; 110, housing; 120, top plate; 121, groove; 122, first through hole; 130, bottom plate; 140, tube body; 150, box body; 160, air supply member; 161, conical shell; 162, transmission pipe; 163, arc-shaped shell; 170, liquid inlet member; 171, annular empty pipe; 1711, second through hole; 172, liquid inlet pipe; 180, air inlet pipe; 190, discharge member; 191, liquid discharge pipe; 192, exhaust pipe;
[0022] 200, flow disturbing mechanism; 210, bracket; 220, flow disturbing rod; 221, round rod; 222, sphere. Detailed implementation manners
[0023] To make the purpose, technical solutions and advantages of the present utility model clearer and more obvious, the present utility model will be further described in detail below in conjunction with the specific implementation manners and with reference to the accompanying drawings. It should be noted that, without conflict, the embodiments of the present utility model and the features in the embodiments can be combined with each other.
[0024] Some embodiments of the present utility model will be described below in conjunction with the accompanying drawings,
[0025] Embodiment 1:
[0026] Combined with Figures 1-5 As shown, this embodiment provides a falling film absorption device for flucytosine, including: a main body mechanism 100 and a flow disturbing mechanism 200.
[0027] Among them, the main body mechanism 100 includes a housing 110, a top plate 120 fixed on the inner wall of the housing 110, a bottom plate 130 fixed on the inner wall of the housing 110, a plurality of tube bodies 140 installed in a circular array between the top plate 120 and the bottom plate 130, a box body 150 fixed on the inner wall of the housing 110, a plurality of air supply members 160 installed in a circular array at the bottom end of the box body 150 and extending into the tube bodies 140, a liquid inlet member 170 fixed on the outside of the box body 150 and extending out of the housing 110, an air inlet pipe 180 installed at the top end of the box body 150 and extending out of the housing 110, and a discharge member 190 installed at the bottom end of the housing 110.
[0028] The housing 110 is used to form a closed environment. The top plate 120 and the bottom plate 130 are used to install the tube body 140 to ensure the stability of the tube body 140. The tube body 140 facilitates the formation of a liquid film along the tube wall by the solution, thereby facilitating the absorption of gas by the solution. Grooves 121 are formed in an annular array at the top end of the top plate 120, and first through holes 122 are formed in an annular array on the inner bottom wall of the grooves 121. The first through holes 122 communicate the grooves 121 with the inner cavity of the tube body 140. Through this setting, the flow rate of the solution entering the tube body 140 can be controlled, avoiding the situation where the solution passes through the tube during large flow rates, and ensuring the absorption efficiency of the solution.
[0029] The box body 150 is used to store the gas for solution absorption. The liquid inlet part 170 is used to send the solution into the inner cavity of the housing 110, including an annular empty tube 171 fixed on the outer side of the box body 150 and a liquid inlet pipe 172 with one end communicating with the annular empty tube 171 and the other end extending out of the housing 110. A plurality of second through holes 1711 are formed in an annular array at the bottom end of the annular empty tube 171. After the solution is sent into the annular empty tube 171 through the liquid inlet pipe 172, it can be discharged through the second through holes 1711, fall above the top plate 120, flow along the surface of the top plate 120 and finally flow into the grooves 121, and then enter the inner cavity of the tube body 140 through the first through holes 122.
[0030] The gas supply part 160 is used to send gas into the inner cavity of the tube body 140, including a conical shell 161 fixed at the bottom end of the box body 150 and communicating with the inner cavity of the box body 150, a transmission pipe 162 fixed at the bottom end of the conical shell 161 and extending through the top plate 120 into the inner cavity of the tube body 140, and an arc-shaped shell 163 fixedly sleeved on the outer side of the transmission pipe 162. The conical shell 161 is used to guide the gas into the transmission pipe 162, the transmission pipe 162 is used to send the gas into the inner cavity of the tube body 140, and the bottom diameter of the arc-shaped shell 163 is slightly smaller than the diameter of the tube body 140, which is used to guide the solution. When the solution enters the tube body 140 through the first through holes 122, the solution can flow along the surface of the arc-shaped shell 163 at this time, and after flowing through the bottom edge of the arc-shaped shell 163, it transitions to the inner wall of the tube body 140 and continues to flow, stably forming a liquid film flowing down on the inner wall of the tube body 140, ensuring the absorption efficiency of the solution.
[0031] The air inlet pipe 180 is used to send gas into the inner cavity of the box body 150. The discharge part 190 includes a liquid discharge pipe 191 installed at the bottom end of the housing 110 and communicating with the inner cavity of the housing 110, and an exhaust pipe 192 installed on one side of the housing 110 and communicating with the inner cavity of the housing 110. The liquid discharge pipe 191 is used to discharge the solution after absorbing the gas, and the exhaust pipe 192 is used to discharge the waste gas.
[0032] The spoiler mechanism 200 includes a plurality of brackets 210 fixed on the inner wall of the housing 110 and spoiler rods 220 mounted on the brackets 210 in an annular array and extending into the inner cavity of the pipe body 140. The brackets 210 are used to mount the spoiler rods 220 to ensure the stability of the spoiler rods 220. The spoiler rods 220 include round rods 221 with the bottom ends fixed on the brackets 210 and the top ends extending into the inner cavity of the pipe body 140, and spheres 222 fixedly arranged on the round rods 221 in an array. The round rods 221 are used to fix the spheres 222 to ensure the stability of the spheres 222. When the gas passes through the spheres 222, the air pressure in front of the spheres 222 is higher than the air pressure behind the spheres 222. Therefore, a low-pressure area behind the spheres 222 can continuously form eddy currents when the air flow passes through. The gas flow rate is reduced through the action of the eddy currents, so that the gas can fully absorb with the liquid film, and further increases the absorption efficiency.
[0033] The working principle and usage process of the present utility model: During use, the solution is sent into the annular empty pipe 171 through the liquid inlet pipe 172 and discharged through the second through holes 1711 in the annular empty pipe 171, falling onto the top end of the top plate 120. Then the solution gathers inside the groove 121 on the top plate 120 and then enters the pipe body 140 through the first through hole 122. After the solution enters the pipe body 140, it flows along the surface of the arc-shaped shell 163 and transitions to the inner wall of the pipe body 140 to continue flowing after flowing through the bottom edge of the arc-shaped shell 163, forming a downward flowing liquid film on the inner wall of the pipe body 140. At the same time, the gas is sent into the box body 150 through the air inlet pipe 180 and then sent into the inner cavity of the pipe body 140 through the conical shell 161 and the transmission pipe 162. When the air flow is sent into the inner cavity of the pipe body 140, due to the action of the spoiler rods 220, eddy currents can be continuously generated when the gas enters the pipe body 140. The inertia of the eddy currents can gradually reduce the gas flow rate, so that the gas can fully absorb with the liquid film.
[0034] Although the embodiments of the present utility model have been shown and described, those of ordinary skill in the art can understand that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principle and spirit of the present utility model. The scope of the present utility model is defined by the claims and their equivalents.
Claims
1. A falling film absorption device for flucytosine, comprising: The main body mechanism (100) and the flow disturbing mechanism (200), characterized in that the main body mechanism (100) includes a housing (110), a top plate (120) fixed on the inner wall of the housing (110), a bottom plate (130) fixed on the inner wall of the housing (110), a plurality of pipe bodies (140) installed in an annular array between the top plate (120) and the bottom plate (130), a box body (150) fixed on the inner wall of the housing (110), a plurality of air supply members (160) installed in an annular array at the bottom end of the box body (150) and extending into the pipe bodies (140), a liquid inlet member (170) fixed on the outer side of the box body (150) and extending out of the housing (110), an air inlet pipe (180) installed at the top end of the box body (150) and extending out of the housing (110), and a discharge member (190) installed at the bottom end of the housing (110); The air supply member (160) includes a conical shell (161) fixed at the bottom end of the box body (150) and communicating with the inner cavity of the box body (150), a transmission pipe (162) fixed at the bottom end of the conical shell (161) and passing through the top plate (120) and extending into the inner cavity of the pipe body (140), and an arc-shaped shell (163) fixedly sleeved on the outer side of the transmission pipe (162), and the bottom diameter of the arc-shaped shell (163) is slightly smaller than the diameter of the pipe body (140); The flow disturbing mechanism (200) includes a plurality of brackets (210) fixed on the inner wall of the housing (110) and flow disturbing rods (220) installed in an annular array on the brackets (210) and extending into the inner cavity of the pipe bodies (140).
2. A falling film absorption device for flucytosine according to claim 1, characterized in that, The flow disturbing rod (220) includes a round rod (221) with the bottom end fixed on the bracket (210) and the top end extending into the inner cavity of the pipe body (140), and spheres (222) fixedly arranged in an array on the round rod (221).
3. A falling film absorption device for flucytosine according to claim 1, characterized in that, The top end of the top plate (120) is provided with grooves (121) in an annular array, and first through holes (122) are provided in an annular array on the inner bottom wall of the grooves (121), and the first through holes (122) communicate the grooves (121) with the inner cavity of the pipe body (140).
4. A falling film absorption device for flucytosine according to claim 1, characterized in that, The liquid inlet member (170) includes an annular empty pipe (171) fixed on the outer side of the box body (150) and a liquid inlet pipe (172) with one end communicating with the annular empty pipe (171) and the other end extending out of the housing (110), and a plurality of second through holes (1711) are provided in an annular array at the bottom end of the annular empty pipe (171).
5. A falling film absorption device for flucytosine according to claim 1, characterized in that, The discharge member (190) includes a liquid discharge pipe (191) installed at the bottom end of the housing (110) and communicating with the inner cavity of the housing (110), and an exhaust pipe (192) installed on one side of the housing (110) and communicating with the inner cavity of the housing (110).