Water absorbent paper capable of developing color when encountering water, and timing device, early pregnancy detection reagent plate, immunochromatography reaction timing detection plate and saliva collection device for immunochromatography diagnosis detection

Abstract

The utility model discloses absorbent paper capable of developing color when encountering water, and a timing device, an early pregnancy detection reagent plate, an immunochromatography reaction timing detection plate and a saliva collection device for immunochromatography diagnosis detection, which relate to the field of absorbent paper for in vitro diagnosis and comprise an absorbent filter paper layer and a covering layer, a color layer is arranged between the water-absorbing filter paper layer and the covering layer, the color layer is printed with a color different from white, and the covering layer is provided with a water-absorbing transparent white coating; by arranging the color layer and the covering layer and utilizing the property that the covering layer becomes transparent when meeting water, whether liquid is fully collected or not is judged according to whether the color layer can be seen or not, and / or a timing function is achieved, so that the detection efficiency and accuracy are improved.

Description

Technical Field

[0001] The utility model relates to the technical field of absorbent paper for in vitro diagnosis, and in particular to absorbent paper that develops color when in contact with water, a timing device for immunochromatographic diagnostic testing, an early pregnancy test reagent plate, an immunochromatographic reaction timing test plate, and a saliva collection device. Background Art

[0002] Lateral flow chromatography rapid diagnostic tests are a common method in medical procedures. However, testing with test strips requires time for the strips to absorb the test fluid, a time that can typically only be determined using a timer. This process requires a separate timing tool; otherwise, it is difficult to intuitively determine the time. This can lead to invalid test results in the reaction zone due to insufficient sample collection time, insufficient sample volume, or excessive reaction time.

[0003] For example, Chinese patent CN217846082U, published on November 18, 2022, relates to a test strip box, comprising a base, a cover body and a snap-fit assembly; the base has a accommodating cavity with an opening on one side, and the bottom wall of the accommodating cavity is provided with an installation area for placing the test strip; the cover body is movable and arranged at a position corresponding to the opening of the base, so as to have a closed box position close to the opening, and an open box position away from the opening, the cover body is provided with a sample addition port and a color development port corresponding to the installation area, and the side of the cover body facing the accommodating cavity is provided with a pressing portion, when the cover body is in the closed box position, the pressing portion is used to press the test strip against the installation area to limit the movement of the test strip, and when the cover body is in the open box position, the pressing portion is used to separate from the test strip; the snap-fit assembly includes a snap-fit portion provided on the outer wall of the cover, and a buckle provided on the base and corresponding to the buckle portion, the buckle is movably arranged to have a locked position engaged with the buckle portion, and an unlocked position disengaged from the buckle portion. The test strip box is identified and judged by the human eye, and cannot accurately judge the length of the reaction time of the reaction area and whether the collection area has absorbed enough liquid to be tested. Utility Model Content

[0004] In response to the problem in the existing technology that it is impossible to accurately judge the reaction time of the reaction zone and whether the collection area has absorbed sufficient test liquid, the utility model proposes a water-colorizing absorbent paper and a timing device for immunochromatographic diagnostic testing, an early pregnancy test reagent plate, an immunochromatographic reaction timing test plate, and a saliva collection device. By judging whether the filter paper changes color, it is possible to judge whether the collection area has absorbed sufficient test liquid and / or the reaction time of the reaction zone.

[0005] In order to solve the above technical problems, the technical solution adopted by the utility model is: a water-coloring absorbent paper, comprising a water-absorbing filter paper layer and a covering layer, a color layer is provided between the water-absorbing filter paper layer and the covering layer, the color layer is printed with a color different from white, and the covering layer is provided with a coating that is transparent when in contact with water.

[0006] A water-chromogenic absorbent paper comprises, from bottom to top, a water-absorbing filter paper layer, a color layer, and a concealing layer. The color layer is printed with color bands, patterns, or fonts in colors such as yellow, red, blue, and green. The concealing layer is preferably provided with a water-transparent white coating. Specifically, the concealing layer is printed with a coating that appears white when dry and transparent when wet. When the water-absorbing filter paper layer is fully absorbed by water, the water will penetrate upwards to the concealing layer. The concealing layer becomes transparent upon contact with water, and the colored bands or patterns on the color layer can be seen, thereby determining the specific situation of the collection or reaction.

[0007] Preferably, the thickness of the water-absorbing filter paper layer is 0.1-3 mm.

[0008] Preferably, a transparent protective layer is provided on the surface of the covering layer. The protective layer is made of transparent waterproof material, which can prevent water from flowing in from the top and make the covering layer transparent, so that the final test result is more accurate.

[0009] A timing device for immunochromatographic diagnostic testing comprises a timing area provided with color-developing blotting paper.

[0010] An early pregnancy test reagent plate includes a first shell and a water collection and absorption rod. A test paper is provided in the first shell. One end of the water collection and absorption rod is overlapped in the first shell. Two sides of one end of the water collection and absorption rod are respectively in contact with the water absorption filter paper layer and the test paper.

[0011] An early pregnancy test reagent plate can observe whether the collection absorbent stick has absorbed enough test sample through the changes in the color of the absorbent paper. When the test sample is sufficiently absorbed, the color of the absorbent paper will change, and the test paper will start the immunochromatographic reaction at the same time.

[0012] Preferably, the first housing is provided with a first reaction zone observation window and a color-developing absorbent paper observation window. The portion of the collection absorbent stick extending from the first housing forms the first collection zone. The first collection zone is used to collect urine samples and facilitate the detection of test strip run-off. The color-developing absorbent paper observation window is used to determine sample sufficiency by observing the color change of the color-developing absorbent paper. The first reaction zone observation window is used to observe reaction results.

[0013] An immunochromatographic reaction timing detection plate comprises a second shell, wherein a test paper is arranged in the second shell, the second shell is provided with a plurality of timing areas, and the timing areas are provided with color developing absorbent paper which is in contact with the absorbent pad of the test paper.

[0014] An immunochromatographic reaction timing test plate has one or more timing zones set on the second shell according to actual conditions. Each timing zone is provided with color-developing absorbent paper that fits the test paper. The reaction time of the test paper is judged according to the color change time of the color-developing absorbent paper in different timing zones, thereby judging whether the test result is valid.

[0015] Preferably, the second housing is provided with a second collection area and a second reaction area observation window. The second collection area collects the liquid to be tested, and the second reaction area observation window observes the test results.

[0016] A saliva collecting device comprises a transparent rod body, wherein absorbent paper is arranged in the transparent rod body, and the absorbent paper is laminated to the absorbent filter paper layer.

[0017] A saliva collection device. When absorbent paper collects a sufficient amount of saliva, a color-developing absorbent paper attached to the absorbent paper will develop color, thereby indicating that a sufficient amount of saliva has been collected.

[0018] Preferably, one end of the transparent rod is connected to the third collection area, and the other end of the transparent rod is connected to a round cover handle. During collection, the round cover handle is held by the hand, and saliva is collected through the suction head of the third collection area.

[0019] The utility model discloses a water-coloring absorbent paper and a timing device for immunochromatographic diagnostic testing, an early pregnancy test reagent plate, an immunochromatographic reaction timing test plate, and a saliva collection device, which have the following substantial effects: any desired different colors / patterns / texts can be designed for color development as needed; different positions of the same color block can display different colors / patterns / texts; the desired color / pattern / text can be displayed at a fixed position; compared with physical color development, the color development effect is stable and will not produce color development deviation due to the environment and sample characteristics; whether the liquid to be collected in the collection area has been fully collected can be judged based on whether the color layer can be seen, thereby improving detection efficiency and accuracy; one or more timing areas are set, and the reaction time can be judged by the color change of the color-developing absorbent paper; and by providing a protective layer, the covering layer is prevented from contacting the liquid from above, thereby further improving the accuracy of the color-developing absorbent paper. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 The color absorbent paper drawing of Example 1.

[0021] Figure 2 This is an unused schematic diagram of embodiments 2, 3, and 4.

[0022] Figure 3 Schematic diagram of the use of embodiments 2, 3 and 4.

[0023] Figure 4 This is an unused schematic diagram of embodiments five, six, and seven.

[0024] Figure 5 Schematic diagrams of the use of embodiments five, six and seven.

[0025] Figure 6 This is an unused schematic diagram of embodiments eight, nine, and ten.

[0026] Figure 7 Schematic diagrams of the use of embodiments eight, nine and ten.

[0027] Figure 8 This is an unused schematic diagram of Example 11.

[0028] Figure 9 This is a schematic diagram of the use of Example 11.

[0029] Wherein: 1. Absorbent filter paper layer, 2. Color layer, 3. Covering layer, 4. Protective layer, 5. First collection area, 6. Observation window for color-developing absorbent paper, 7. Observation window for first reaction area, 8. First housing, 9. Second housing, 10. First timing area, 11. Second timing area, 12. Observation window for second reaction area, 13. Second collection area, 14. Round cover handle, 15. Transparent rod, 16. Absorbent paper, 17. Third collection area, 18. Third timing area, 19. Fourth timing area, 20. Second reaction area, 21. Fourth collection area DETAILED DESCRIPTION

[0030] The specific implementation of the present invention will be further described below with reference to specific embodiments and accompanying drawings.

[0031] Embodiment one:

[0032] A water-dispersing paper, such as Figure 1 As shown, the color-developing absorbent paper mainly consists of four parts: a water-absorbing filter paper layer 1, a color layer 2, a covering layer 3, and a protective layer 4. The color layer 2 can be printed with more conspicuous colors such as yellow, red, blue, and green, or printed with patterns, fonts, or color bands of different colors. The covering layer 3 is printed with a white paint that turns from white to transparent when exposed to water. Because the protective layer 4 is transparent, the pattern, fonts, or color bands on the color layer 2 can be seen when the covering layer 3 becomes transparent when exposed to water. During use, the water-absorbing filter paper layer 1 of the color-developing absorbent paper is usually attached to a test paper. The liquid sample is absorbed from the test paper by the water-absorbing filter paper layer 1. The sample then penetrates from the water-absorbing filter paper layer 1 to the covering layer 3 from bottom to top, and the color of the color-developing absorbent paper is then visible.

[0033] In this embodiment, the absorbent filter paper layer 1 in the color-developing absorbent paper has a thickness of 2.5 mm. The color-developing absorbent paper can also include one or more color layers 2 to enhance the color development effect. Based on the color development characteristics, water absorption capacity, and water absorption rate of the color-developing absorbent paper, the color-developing absorbent paper can be attached to different locations in different application scenarios (such as one end of the collection absorbent stick described in Example 2, one end of the absorbent pad of the test paper described in Example 3, etc.), indicating whether the corresponding collection area has absorbed sufficient test liquid (Examples 2 and 4) and / or the length of time it takes for the reaction area to fully react and produce an observable result (Example 3).

[0034] Example 2:

[0035] An early pregnancy test kit, such as Figure 2 or Figure 3 As shown, the pregnancy test stick includes a first shell 8, which is divided into an upper shell and a lower shell from top to bottom. The detection reagent strip is fixed in the lower shell. The detection test paper strip is composed of a sample pad, a marker binding pad, a nitrocellulose membrane and a water-absorbing pad overlapped in sequence on a PVC bottom plate, and a water-absorbing rod for collecting water fixed between the shells. Symmetrical staples are respectively provided on the upper edge of the lower shell of the pregnancy test stick and on the inner side of the edge of the lower shell. The upper shell is provided with a groove at the corresponding staple installation position, and the groove and the staple are used in conjunction to achieve a fixed connection between the upper shell, the lower shell and the water-absorbing rod for collecting water. The upper shell is provided with a first reaction zone observation window 7 and a color developing water-absorbing paper observation window 6. The upper shell and the lower shell are provided with anti-slip grooves on one end away from the water-absorbing rod for collecting water, which increases the friction between the thumb and the shell.

[0036] The first collection area 5 is the extended portion of the collection absorbing rod. One side of the collection absorbing rod contacts the absorbent filter paper layer 1 of the color developing filter paper on one side and the sample pad of the test paper on the other side. The color developing absorbing paper consists of the absorbent filter paper layer 1, the color layer 2, and the concealing layer 3. In this embodiment, the color layer 2 is printed with a blue color band. The concealing layer 3 is printed with a white coating that turns from white to transparent when exposed to water. When the concealing layer 3 becomes transparent when exposed to water, the blue color band on the color layer 2 becomes visible. During use, the absorbent filter paper layer 1 of the color developing absorbing paper is attached to the collection absorbing rod. The absorbent filter paper layer 1 absorbs water from the collection absorbing rod. The water then permeates upward from the absorbent filter paper layer 1 to the concealing layer 3, causing a visible color change on the color developing absorbing paper. The color change of the color developing absorbing paper is used to determine whether sufficient test liquid has been absorbed for testing.

[0037] The extended collection absorbent stick contacts the urine and begins to collect the sample. When enough sample is collected, the color developing absorbent paper is completed and the test paper begins the immunochromatographic reaction to test the HCG concentration in the urine to determine whether a sufficient amount of the sample to be tested has been absorbed.

[0038] Example 3:

[0039] A pregnancy test kit is provided. This embodiment, based on the second embodiment, sets the thickness of the absorbent filter paper layer 1 to 0.54 mm. In actual production applications, the thickness of the absorbent filter paper layer 1 can be varied according to the specifications and requirements of the pregnancy test kit to meet different collection requirements.

[0040] Example 4:

[0041] A pregnancy test kit is provided. This embodiment, based on the second embodiment, adds a protective layer 4 made of a transparent, waterproof material above the cover layer 3 of the absorbent paper. The protective layer prevents liquid from the collection rod or from accidentally contacting the sample during collection from seeping through the cover layer 3. This could cause the color layer 2 to display prematurely, resulting in insufficient sample volume and affecting the test results.

[0042] Embodiment 5:

[0043] This embodiment provides an immunochromatographic reaction timing test plate. When testing specimens using immunochromatographic methods, both the sample absorption by the test strip and the antigen-antibody reaction require time. Therefore, immunochromatographic tests require timing, with readings taken within a specific timeframe. However, existing products lack a built-in timing function and require a separate timer. Reading the results too early or too late can affect the accuracy of the test results.

[0044] By setting different timing zones and using the changes in the color of the absorbent paper, the reaction time can be judged. Figure 4 and Figure 5 As shown, in this embodiment, the test paper is located in the second shell 9, and the second shell 9 is composed of an upper shell and a lower shell, and a test paper is fixed between the upper shell and the lower shell. A number of openings are provided on the upper shell, namely the second collection area 13, the second reaction area and the timing area. The second reaction area is provided with a second reaction area observation window 12 for observation. The second collection area 13 and the timing area are located at both ends of the upper shell, and the second reaction area is located in the middle of the upper shell. The second collection area 13 is elliptical as a whole, and an opening is provided in the middle for dripping liquid. Through this opening, the liquid can be dripped directly onto the sample collection pad of the test paper. The second reaction area is elongated, and a long strip opening is provided in the middle for observing specific experimental phenomena.

[0045] One or more timing zones can be provided. In this embodiment, two timing zones are provided: a first timing zone 10 and a second timing zone 11. Both the first and second timing zones 10, 11 are provided with color-developing absorbent paper. One side of the absorbent filter paper layer 1 of the color-developing absorbent paper is attached to the absorbent pad end of the test paper (away from the sample collection pad end). The color-developing absorbent paper consists of the absorbent filter paper layer 1, the color layer 2, and the concealing layer 3. In this embodiment, the color layer 2 is printed with a yellow ribbon. The concealing layer 3 is printed with a white coating that turns from white to transparent upon contact with water. When the concealing layer 3 becomes transparent upon contact with water, the yellow ribbon on the color layer 2 becomes visible. During use, the absorbent filter paper layer 1 of the color-developing absorbent paper is attached to the water collection stick. The absorbent filter paper layer 1 absorbs water from the water collection stick. The water then permeates upward from the absorbent filter paper layer 1 to the concealing layer 3, causing a visible color change on the color-developing absorbent paper. The color change of the color-developing absorbent paper is used to determine whether sufficient test liquid has been absorbed for detection.

[0046] After the liquid drips into the second collection area 13, it is chromatographed through the test paper to the two timing zones. Since the two timing zones are at different distances from the second collection area 13, the time it takes for the color-developing absorbent paper in the two timing zones to change color is also different. Therefore, one timing zone can be set to indicate the time during which the experimental phenomenon can be observed, and the other can be set to indicate when the immunochromatographic reaction of the test paper times out and the test result is invalid, thereby accurately controlling the effective observation time of the experiment. In this embodiment, when the second timing zone 11 changes color, the reaction result in the second reaction zone can be read; when the first timing zone 10 changes color, reading the reaction result in the second reaction zone may be invalid due to the long reaction time.

[0047] Example 6:

[0048] An immunochromatographic reaction timing detection plate. Based on Example 5, this embodiment sets the thickness of the absorbent filter paper layer 1 to 0.60 mm. In actual production applications, the color-developing absorbent paper with absorbent filter paper layers 1 of varying thicknesses can be replaced according to the specific effective time period of the immunochromatographic reaction, thereby achieving timing for different detection times.

[0049] Embodiment seven:

[0050] An immunochromatographic reaction timing test plate, based on Example 5, includes a protective layer 4 made of a transparent, waterproof material, above the cover layer 3 of absorbent paper. The protective layer prevents liquid from accidentally seeping downward from above the cover layer 3, which could cause the color layer 2 to appear prematurely, leading to inaccurate timing in the first timing zone 10 and prematurely checking the reaction results, resulting in inaccurate readings.

[0051] Embodiment 8:

[0052] This embodiment provides a saliva collection device. When collecting saliva, it is generally difficult to control the amount of saliva collected to meet the accuracy of the test results. Figure 6 or Figure 7 As shown, this embodiment discloses the use of color-developing absorbent paper in a saliva collection device. The saliva collection device includes a transparent rod 15, one end of which is connected to a sponge suction nozzle, which serves as a third collection area 17. The end of the transparent rod 15, away from the suction nozzle, is connected to a round handle 14. Inside the transparent rod 15 is a rod-shaped absorbent paper 16, onto which color-developing absorbent paper is fixed. The absorbent filter paper layer 1 of the color-developing absorbent paper is bonded to the absorbent paper 16. The color-developing absorbent paper comprises the absorbent filter paper layer 1, a color layer 2, and a concealing layer 3. In this embodiment, a red ribbon is printed on the color layer 2. The concealing layer 3 is printed with a white coating that turns transparent when exposed to water. When the concealing layer 3 becomes transparent when exposed to water, the red ribbon on the color layer 2 becomes visible. During use, the absorbent filter paper layer 1 of the color-developing absorbent paper is attached to a water collection stick. The absorbent filter paper layer 1 absorbs water from the water collection stick. The water then permeates upward from the absorbent filter paper layer 1 toward the cover layer 3, causing a visible color change on the color-developing absorbent paper. This color change indicates whether sufficient test liquid has been absorbed for testing.

[0053] When collecting saliva, the collector holds the round cover handle 14 and puts the suction head into the mouth. After the suction head collects enough saliva, it will be transferred to the absorbent paper 16 in the transparent rod 15. When the color-developing absorbent paper changes color, it prompts the person that enough saliva has been collected, which serves as a saliva collection information prompt and improves the convenience of saliva collection.

[0054] Embodiment 9:

[0055] A saliva collection device, based on Example 8, in this embodiment, the absorbent filter paper layer 1 has a thickness of 0.61 mm. In actual production applications, depending on the desired saliva volume and the placement of the color-developing absorbent paper, color-developing absorbent paper with different absorbent filter paper layer thicknesses can be selected to detect whether a sufficient amount of saliva has been collected.

[0056] Embodiment 10:

[0057] A saliva collection device, based on Example 8, adds a protective layer 4 made of a transparent, waterproof material above the cover layer 3 of the absorbent paper. The protective layer prevents accidental liquid infiltration from above the cover layer 3 during production and installation. When a sufficient sample volume is collected, the color-developing absorbent paper changes.

[0058] Example 11:

[0059] This embodiment provides an immunochromatographic test strip with a timing function. During immunochromatographic testing, the test strip absorbs the sample and the antigen-antibody reaction takes time. Therefore, immunochromatographic testing requires timing, with readings taken within a specific time. However, existing products lack a timing function and require a separate timer. Reading the result too early or too late can affect the accuracy of the test result.

[0060] By setting different timing zones and using the changes in the color of the absorbent paper, the reaction time can be judged. Figure 8 and Figure 9 As shown, in the test paper of this embodiment, the liquid is dropped on the sample collection pad of the test paper, and reacts through chromatography to the timing area, and the reading time is determined according to the color change of the color-developing absorbent paper.

[0061] One or more timing zones can be provided. In this embodiment, two timing zones are provided: a third timing zone 18 and a fourth timing zone 19. Both the third timing zone 18 and the fourth timing zone 19 are provided with color-developing absorbent paper. One side of the absorbent filter paper layer 1 of the color-developing absorbent paper is attached to the absorbent pad end of the test paper (away from the sample collection pad end). The color-developing absorbent paper comprises the absorbent filter paper layer 1, a color layer 2, and a covering layer 3. In this embodiment, the word "Invalid" is printed on the color layer 2 of the third timing zone 18, and the word "Read Time" is printed on the color layer 2 of the fourth timing zone 19. The covering layer 3 is printed with a white coating that turns transparent when exposed to water. When the covering layer 3 becomes transparent when exposed to water, the text on the color layer 2 of the third timing zone 18 and the fourth timing zone 19, respectively, can be seen. During use, the absorbent filter paper layer 1 of the color-developing absorbent paper is attached to the water-collecting absorbent stick. The absorbent filter paper layer 1 absorbs water from the water-collecting absorbent stick. Then, the water penetrates from the absorbent filter paper layer 1 from bottom to top to the covering layer 3, and the color of the color-developing absorbent paper can be seen to change.

[0062] When the liquid drips into the fourth collection area 21, it will be chromatographed to the two timing areas through the test paper. Since the two timing areas are at different distances from the fourth collection area 21, the time it takes for the color-developing absorbent paper in the two timing areas to change color is also different. Another setting is that the immunochromatographic reaction of the test paper times out and the test result is invalid, thereby accurately controlling the effective observation time of the experiment. In this embodiment, when the text "Read Time" appears in the fourth timing area 19, the reaction result in the third reaction area 20 can be read; when the text "Invalid" appears in the third timing area 18, reading the reaction result in the second reaction area may result in an invalid test result due to the long reaction time. This embodiment uses the text "Read Time" and "Invalid", and texts such as "OK", "NO", and product name" can also be used.

[0063] The above embodiments merely illustrate several implementations of the present invention. While the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent. It should be noted that a person skilled in the art would be able to make numerous variations and improvements without departing from the scope of the present invention, all of which fall within the scope of protection of the present invention.

Claims

1. A water-discoloring absorbent paper, characterized in that: It comprises a water-absorbing filter paper layer and a covering layer. A color layer is provided between the water-absorbing filter paper layer and the covering layer. The color layer is printed with a color different from white. The covering layer is provided with a coating that is transparent when in contact with water.

2. The water-discoloring absorbent paper according to claim 1, characterized in that: The thickness of the water-absorbing filter paper layer is 0.1-3 mm.

3. The water-discoloring absorbent paper according to claim 1, characterized in that: A transparent protective layer is provided on the surface of the covering layer.

4. A timing device for immunochromatographic diagnostic testing, using the water-chromogenic absorbent paper according to claim 1, characterized in that: The utility model comprises a timing area, wherein the timing area is provided with color-developing absorbent paper.

5. An early pregnancy test reagent plate, using the water-chromogenic absorbent paper according to any one of claims 1 to 3, comprising a first shell and a water collection absorbent rod, wherein the test paper is provided in the first shell, characterized in that: One end of the water collecting and absorbing rod is overlapped in the first shell, and two surfaces of the one end of the water collecting and absorbing rod are respectively attached to the water absorbing filter paper layer and the detection test paper.

6. An early pregnancy test reagent plate according to claim 5, characterized in that: The first shell is provided with a first reaction area observation window and a color developing water absorbing paper observation window, and the water collecting absorbing rod part extending out of the first shell part is the first collecting area.

7. An immunochromatographic reaction timing test plate, using the water-chromogenic absorbent paper according to any one of claims 1 to 3, comprising a second shell, wherein the test paper is disposed in the second shell, characterized in that: The second shell is provided with a plurality of timing areas, and the timing areas are provided with color-developing absorbent paper that fits the absorbent pad of the test paper.

8. The immunochromatographic reaction timing detection plate according to claim 7, characterized in that: The second shell is provided with a second collection area and a second reaction area observation window.

9. A saliva collection device, using the water-chromogenic absorbent paper according to any one of claims 1 to 3, characterized in that: The utility model comprises a transparent rod body, wherein absorbent paper is arranged in the transparent rod body, and the absorbent paper is bonded to the absorbent filter paper layer.

10. The saliva collection device according to claim 9, characterized in that: One end of the transparent rod is connected to the third collection area, and the other end of the transparent rod is connected to the round cover handle.

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