Filtering and collecting device

By designing an integrated filtration and collection device, the problem of independent filters requiring separate sterilization is solved, efficient use of biopharmaceutical equipment and consumables is achieved, and the convenience and efficiency of single-use are maintained.

CN223233467UActive Publication Date: 2025-08-19BIO-LINK PHARM APPL SYST (JIANGSU) CO LTD
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Patent Information

Application Number
CN202422485300.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-14
Publication Date
2025-08-19
Estimated Expiration
2034-10-14

AI Technical Summary

Technical Problem

In the prior art, the filters independently installed in the art need to be sterilized separately when used, resulting in cumbersome use of biopharmaceutical equipment and consumables, and the rapid and efficient advantages of disposable and discardable types are lost.

Method used

A filter collection device is designed, including a sealed collection bag, a sealed pipeline bag and a sealed filter bag that is connected in sequence. It has a built-in filter, which connects the filter with the collection bag through the connecting pipe to realize integrated sterilization treatment and avoids separate sterilization steps.

Benefits of technology

The use process is simplified, the speed and efficiency of biopharmaceutical equipment and consumables are maintained, the advantages of one-time use are continued, and the tedious steps of individual sterilization are avoided.

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Abstract

The utility model provides a filtering and collecting device which comprises a sealed collecting bag, a sealed pipeline bag and a sealed filtering bag which are connected in sequence, a filter is arranged in the sealed filtering bag, a connecting pipeline is arranged in the sealed pipeline bag, one end of the connecting pipeline penetrates through the sealed pipeline bag and the sealed filtering bag in sequence and is connected with the filter, and the other end of the connecting pipeline is connected with the filter. The other end of the connecting pipeline sequentially penetrates through the sealed pipeline bag and the sealed collecting bag and is communicated with the interior of the sealed collecting bag, and the filter is used for being communicated with an external reaction device so as to filter the liquid medicine and guide a target product into the sealed collecting bag through the connecting pipeline. Before the filter is used, the connecting pipeline and the filter can be sterilized, and the connecting pipeline and the filter are respectively arranged in the sealed pipeline bag and the sealed filter bag, so that the integrated design simplifies the use process, and the filter does not need to be sterilized independently when being used; and the advantages of rapidness and efficiency of disposable / disposable biopharmaceutical equipment and consumables are continued.
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Description

Technical Field

[0001] The utility model relates to the technical field of medical equipment, in particular to a filtering and collecting device. Background Art

[0002] Disposable / disposable biopharmaceutical equipment and consumables have been irradiated and sterilized before delivery to customers and are always in a sealed state. Customers can use them directly after receiving them without the need for further irradiation and sterilization. During the process of cell culture or microbial reaction using disposable / disposable biopharmaceutical equipment and consumables, the target product will continue to accumulate in the reaction vessel. In order to continue production, a filter can be used to filter out the target product to reduce the concentration of the drug solution and achieve the purpose of continuous production.

[0003] Currently, filters are usually independent devices. When in use, they need to be connected to the reaction device, and then connected to the collection device through a pipeline. The drug solution is drawn from the reaction device into the filter, filtered by the filter, and then the target product is transported to the collection device.

[0004] However, the independently installed filter needs to be sterilized separately before being connected to the sterilized reaction device and collection device. The whole process is relatively cumbersome and loses the advantages of speed and efficiency of disposable / disposable biopharmaceutical equipment and consumables. Utility Model Content

[0005] In response to the shortcomings of the existing technology, the purpose of the present invention is to provide a filtering and collecting device, which aims to solve the technical problem that the independent filters in the existing technology need to be sterilized separately before being connected to the sterilized reaction device and collection device during use. The whole process is relatively cumbersome and loses the advantages of speed and efficiency of disposable / disposable biopharmaceutical equipment and consumables.

[0006] In order to achieve the above purpose, the present invention is implemented through the following technical solutions:

[0007] A filtration and collection device comprises a sealed collection bag, a sealed pipeline bag and a sealed filter bag connected in sequence, a filter is arranged in the sealed filter bag, a connecting pipeline is arranged in the sealed pipeline bag, one end of the connecting pipeline passes through the sealed pipeline bag and the sealed filter bag in sequence and is connected to the filter, the other end of the connecting pipeline passes through the sealed pipeline bag and the sealed collection bag in sequence and is connected to the interior of the sealed collection bag, the filter is used to connect to an external reaction device to filter the drug solution, and the target product is introduced into the sealed collection bag through the connecting pipeline.

[0008] Compared with the prior art, the beneficial effect of the present invention is that: by providing the sealed collection bag, the sealed pipeline bag and the sealed filter bag connected in sequence, the connecting pipeline and the filter can be sterilized before the filter is used, and the connecting pipeline and the filter are placed in the sealed pipeline bag and the sealed filter bag respectively, and the filter and the sealed collection bag are connected through the connecting pipeline to form the sterilized filter collection device. When in use, the filter is directly connected to the external reaction device to introduce the target product into the sealed collection bag. The integrated design simplifies the use process, avoids the need to sterilize the filter separately when in use, and continues the advantages of speed and efficiency of disposable / disposable biopharmaceutical equipment and consumables.

[0009] Furthermore, a plurality of connecting branches are provided at one end of the connecting pipeline facing the filter, a plurality of filter outlets are provided on the filter, and the plurality of filter outlets correspond one to one with the plurality of connecting branches.

[0010] Furthermore, the opposite ends of the filter are respectively connected to an inlet pipe and an outlet pipe, the end of the inlet pipe facing away from the filter passes through the sealed filter bag and is connected to the inlet docking chuck, and the end of the outlet pipe facing away from the filter passes through the sealed filter bag and is connected to the outlet docking chuck, and the inlet docking chuck and the outlet docking chuck are respectively used to connect to the liquid outlet and liquid inlet of an external reaction device.

[0011] Furthermore, an opening and closing mechanism is provided on the connecting pipeline, and the opening and closing mechanism is used to open or close the connecting pipeline.

[0012] Furthermore, the opening and closing mechanism is a pipeline clamp, and the pipeline clamp is arranged on the connecting pipeline.

[0013] Furthermore, the sealed collection bag and the sealed filter bag are welded to opposite ends of the sealed pipeline bag respectively.

[0014] Furthermore, quick cutting lines are provided at opposite ends of the sealed tubing bag.

[0015] Furthermore, the top of the sealed filter bag is connected to the first extension portion, and the first extension portion is provided with a first lifting port.

[0016] Furthermore, the top of the sealed collection bag is connected to the second extension portion, and the second extension portion is provided with a second opening.

[0017] Furthermore, a breathable film package is provided on the second extension portion. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1This is a schematic structural diagram of a filtering and collecting device in an embodiment of the present utility model;

[0019] Description of main component symbols:

[0020] 10. Sealed collection bag; 110. Second extension; 120. Second lifting port; 130. Breathable membrane bag; 20. Sealed pipeline bag; 30. Sealed filter bag; 310. First extension; 320. First lifting port; 40. Filter; 410. Inlet pipe; 420. Outlet pipe; 430. Inlet docking chuck; 440. Outlet docking chuck; 50. Connecting pipeline; 510. Connecting branch pipe; 60. Opening and closing mechanism.

[0021] The following specific embodiments will further illustrate the present invention in conjunction with the above-mentioned drawings. DETAILED DESCRIPTION

[0022] To facilitate understanding of the present invention, a more comprehensive description of the present invention will be provided below with reference to the accompanying drawings. The drawings illustrate several embodiments of the present invention. However, the present invention can be implemented in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided to provide a more thorough and comprehensive understanding of the present invention.

[0023] It should be noted that when an element is referred to as being "fixed to" another element, it may be directly on the other element or there may be an intermediate element. When an element is referred to as being "connected to" another element, it may be directly connected to the other element or there may be an intermediate element. The terms "vertical," "horizontal," "left," "right," and similar expressions used herein are for illustrative purposes only.

[0024] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the art to which this invention pertains. The terms used herein in the specification of this invention are intended only to describe specific embodiments and are not intended to limit the invention. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0025] See also Figure 1The filter collection device in the embodiment of the present invention includes a sealed collection bag 10, a sealed pipeline bag 20, and a sealed filter bag 30 connected in sequence. It should be noted that the sealed collection bag 10, the sealed pipeline bag 20, and the sealed filter bag 30 are not connected to each other. The sealed collection bag 10 and the sealed filter bag 30 are welded to the opposite ends of the sealed pipeline bag 20, respectively. Quick cutting lines are set at the opposite ends of the sealed pipeline bag 20. The quick cutting lines are set at the welding points between the sealed pipeline bag 20 and the sealed collection bag 10 and the welding points between the sealed pipeline bag 20 and the sealed filter bag 30. By setting the quick cutting lines, the sealed collection bag 10, the sealed pipeline bag 20, and the sealed filter bag 30 can be quickly detached.

[0026] A filter 40 is provided in the sealed filter bag 30, and the filter 40 is used to connect to an external reaction device to filter the medicinal liquid. Specifically, the opposite ends of the filter 40 are connected to an inlet pipe 410 and an outlet pipe 420, respectively. The end of the inlet pipe 410 facing away from the filter 40 passes through the sealed filter bag 30 and is connected to an inlet docking chuck 430. The end of the outlet pipe 420 facing away from the filter 40 passes through the sealed filter bag 30 and is connected to an outlet docking chuck 440. The inlet docking chuck 430 and the outlet docking chuck 440 are respectively used to connect to the liquid outlet and liquid inlet of an external reaction device. The external reaction device introduces the medicinal liquid into the inlet docking chuck 430 through the liquid outlet. The medicinal liquid produces a target product after being filtered in the filter 40, and the remaining medicinal liquid flows back to the liquid inlet of the external reaction device through the outlet docking chuck 440, and then flows back into the external reaction device.

[0027] A connecting pipe 50 is provided in the sealed pipe bag 20, one end of the connecting pipe 50 passes through the sealed pipe bag 20 and the sealed filter bag 30 in sequence and is connected to the filter 40, and the other end of the connecting pipe 50 passes through the sealed pipe bag 20 and the sealed collection bag 10 in sequence and is connected to the interior of the sealed collection bag 10, and the target product in the filter 40 is introduced from the filter 40 into the sealed collection bag 10 through the connecting pipe 50.

[0028] By setting the sealed collection bag 10, the sealed pipeline bag 20 and the sealed filter bag 30 connected in sequence, the connecting pipeline 50 and the filter 40 can be sterilized before the filter 40 is used, and the connecting pipeline 50 and the filter 40 are placed in the sealed pipeline bag 20 and the sealed filter bag 30 respectively. The filter 40 and the sealed collection bag 10 are connected through the connecting pipeline 50 to form the sterilized filtration and collection device. When in use, the filter 40 is directly connected to the external reaction device to introduce the target product into the sealed collection bag 10. The integrated design simplifies the use process, avoids the need to sterilize the filter 40 separately when in use, and continues the advantages of speed and efficiency of disposable / disposable biopharmaceutical equipment and consumables. It should be noted that the sealed collection bag 10 and the connecting pipe 50, the sealed filter bag 30 and the connecting pipe 50, the sealed filter bag 30 and the inlet pipe 410 and the outlet pipe 420 are all welded to ensure the sealing of the sealed collection bag 10, the sealed filter bag 30 and the sealed pipeline bag 20, and to prevent external air from entering the sealed collection bag 10, the sealed filter bag 30 or the sealed pipeline bag 20 during transportation, causing pollution.

[0029] The connecting pipe 50 is provided with a plurality of connecting branches 510 at one end thereof facing the filter 40. The filter 40 is provided with a plurality of filter outlets. The plurality of filter outlets 40 correspond one-to-one with the plurality of connecting branches 510. In this embodiment, two connecting branches 510 are provided at the end thereof facing the filter 40, and the filter 40 is provided with two filter outlets 40. By adjusting the number of connecting branches 510 and the filter outlets 40, the filtration efficiency of the filter 40 can be adjusted to ensure efficient diversion of the target product.

[0030] An opening and closing mechanism 60 is provided on the connecting pipeline 50, and the opening and closing mechanism 60 is used to make the connecting pipeline 50 conductive or closed. When the filter 40 is not in use or after the sealed collection bag 10 completes the collection of the target product, the opening and closing mechanism 60 controls the connecting pipeline 50 to be closed. When the filter 40 is in use, the opening and closing mechanism 60 controls the connecting pipeline 50 to be conductive. In this embodiment, the opening and closing mechanism 60 is a pipeline clamp, and the pipeline clamp is provided on the connecting pipeline 50.

[0031] The top of the sealed filter bag 30 is connected to the first extension portion 310, which has a first lifting opening 320. The provision of the first lifting opening 320 facilitates lifting the filter collection device, improving its portability. The top of the sealed collection bag 10 is connected to the second extension portion 110, which has a second lifting opening 120. It is understood that after the target product is collected, the sealed tube bag 20 is separated from the sealed collection bag 10, and the connecting tube 50 is disconnected using a tube sealing machine, the provision of the second lifting opening 120 facilitates carrying and transporting the sealed collection bag 10. It should be noted that welds are provided around both the first lifting opening 320 and the second lifting opening 120 to reinforce them. It can be understood that a third extension portion is provided on the sealed tube bag 20, and the connection method between the first extension portion 310, the third extension portion and the second extension portion 110 is consistent with the connection method between the sealed filter bag 30, the sealed tube bag 20 and the sealed collection bag 10, and will not be repeated here.

[0032] A breathable membrane package 130 is provided on the second extension portion 110 , and the breathable membrane package 130 is connected to the interior of the sealed collection bag 10 to discharge the continuously expanding air in the sealed collection bag 10 and prevent external air from entering the sealed collection bag 10 .

[0033] Throughout this specification, reference to terms such as "one embodiment," "some embodiments," "examples," "specific examples," or "some examples" means that the specific features, structures, materials, or characteristics described in conjunction with that embodiment or example are included in at least one embodiment or example of the present invention. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

[0034] The above-described embodiments merely represent several implementation methods of the present invention. While the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the present invention. It should be noted that a person skilled in the art would be able to make various modifications and improvements without departing from the concept of the present invention, and these modifications and improvements fall within the scope of protection of the present invention. Therefore, the scope of protection of the present invention shall be determined by the appended claims.

Claims

1. A filtering and collecting device, characterized in that: It includes a sealed collection bag, a sealed pipeline bag and a sealed filter bag connected in sequence, a filter is arranged in the sealed filter bag, a connecting pipeline is arranged in the sealed pipeline bag, one end of the connecting pipeline passes through the sealed pipeline bag and the sealed filter bag in sequence and is connected to the filter, the other end of the connecting pipeline passes through the sealed pipeline bag and the sealed collection bag in sequence and is connected to the interior of the sealed collection bag, the filter is used to connect to an external reaction device to filter the drug solution, and the target product is introduced into the sealed collection bag through the connecting pipeline.

2. The filtering and collecting device according to claim 1, characterized in that: A plurality of connecting branches are arranged at one end of the connecting pipeline facing the filter. A plurality of filter outlets are provided on the filter, and the plurality of filter outlets correspond to the plurality of connecting branches in a one-to-one manner.

3. The filtering and collecting device according to claim 1, characterized in that: The opposite ends of the filter are connected to an inlet pipe and an outlet pipe respectively. The end of the inlet pipe facing away from the filter passes through the sealed filter bag and is connected to the inlet docking chuck. The end of the outlet pipe facing away from the filter passes through the sealed filter bag and is connected to the outlet docking chuck. The inlet docking chuck and the outlet docking chuck are used to connect to the liquid outlet and liquid inlet of an external reaction device respectively.

4. The filtering and collecting device according to claim 1, characterized in that: An opening and closing mechanism is provided on the connecting pipeline, and the opening and closing mechanism is used to open or close the connecting pipeline.

5. The filtering and collecting device according to claim 4, characterized in that: The opening and closing mechanism is a pipeline clamp, and the pipeline clamp is arranged on the connecting pipeline.

6. The filtering and collecting device according to claim 1, characterized in that: The sealed collection bag and the sealed filter bag are welded to opposite ends of the sealed pipeline bag respectively.

7. The filtering and collecting device according to claim 6, characterized in that: The two opposite ends of the sealed tubing bag are both provided with quick cutting lines.

8. The filtering and collecting device according to claim 1, characterized in that: The top of the sealed filter bag is connected to the first extension portion, and the first extension portion is provided with a first lifting port.

9. The filtering and collecting device according to claim 1, characterized in that: The top of the sealed collection bag is connected to the second extension part, and the second extension part is provided with a second lifting opening.

10. The filtering and collecting device according to claim 9, characterized in that: A breathable membrane package is provided on the second extension portion.