Equipment for separating and purifying imidacloprid raw medicine by high-efficiency chromatography

Abstract

The utility model discloses efficient chromatographic separation and purification equipment for imidacloprid raw medicine, which comprises a storage box, a chromatographic column, a conveying component, a material level sensor and an electronic scale, the conveying component is used for conveying the medicine in the storage box into the chromatographic column, the material level sensor is used for monitoring the position of the medicine in the storage box, and the electronic scale is used for measuring the position of the medicine in the storage box. The electronic scale is used for monitoring the weight of the medicament in the storage box, the controller is used for controlling operation of the conveying assembly, and the screen is used for screening and filtering the medicament; by means of the design of the screen, the material level sensor, the controller, the electronic scale and the conveying assembly, conveyed materials are filtered in a multi-stage mode through the screen, impurities in the materials are screened out step by step, the purity of products is improved, meanwhile, the peristaltic pump and the electronic scale are arranged in a matched mode, the material conveying speed can be controlled and adjusted, and the conveying efficiency is improved. Feeding is accurately controlled, the separation effect is improved, and meanwhile unnecessary solvent consumption and waste liquid generation are reduced.

Description

Technical Field

[0001] The utility model relates to the technical field of pesticide production equipment, in particular to high-efficiency chromatographic separation and purification equipment for imidacloprid technical medicine. Background Art

[0002] Imidacloprid, as a highly effective, low-toxic, broad-spectrum nitromethylene systemic insecticide, occupies an important position in agricultural production. However, during the production process of imidacloprid, various impurities are generated due to unfiltered impurities in the raw materials themselves and improper reaction conditions leading to incomplete reactions. These impurities will exist in the final product, which not only affects the purity of the imidacloprid technical, but also directly affects the efficacy of the product. Utility Model Content

[0003] The purpose of the utility model is to provide a high-efficiency chromatographic separation and purification device for imidacloprid technical drug, so as to solve the problems raised in the above background technology.

[0004] To achieve the above-mentioned object, the present invention provides the following technical solution: a high-efficiency chromatographic separation and purification device for imidacloprid technical drug, comprising a storage box and a chromatography column, wherein the storage box is used for storing the drug, and the chromatography column is used for purifying the drug, and the storage box is arranged on one side of the chromatography column, and further comprising:

[0005] A conveying assembly, which is used to convey the medicine in the storage box to the inside of the chromatography column;

[0006] A material level sensor, which is used to monitor the position of the medicine inside the storage box;

[0007] An electronic scale for monitoring the weight of the medicine inside the storage box;

[0008] A controller, the controller being used to control the operation of the conveying assembly;

[0009] The sieve is used for screening and filtering medicines, and the sieve is arranged inside the chromatography column.

[0010] Preferably, the delivery assembly includes a peristaltic pump and a delivery tube, one end of the delivery tube extends into the interior of the storage box, the other end of the delivery tube is connected to the top of the chromatography column, and the delivery tube is sleeved on the output end of the peristaltic pump.

[0011] Preferably, the peristaltic pump is used to transport the material inside the delivery tube, and the input end of the peristaltic pump is electrically connected to the output end of the controller.

[0012] Preferably, a flow sensor is provided on the outer wall of one end of the conveying pipe, and the flow sensor is used to monitor the flow rate of the material inside the conveying pipe. The output end of the flow sensor is electrically connected to the input end of the controller.

[0013] Preferably, the back side of the material level sensor is fixedly connected to the front side of the material storage box, and the output end of the material level sensor is electrically connected to the input end of the controller.

[0014] Preferably, the electronic scale is arranged at the bottom end of the storage box, and the output end of the electronic scale is electrically connected to the input end of the controller.

[0015] Preferably, a control system is provided inside the controller, and the control system includes an input module, a judgment module, a comprehensive calculation module and an output module. The input end of the input module is electrically connected to the output ends of the flow sensor, the material level sensor and the electronic scale respectively, and the output end of the input module is electrically connected to the input ends of the judgment module and the comprehensive calculation module respectively. The output ends of the judgment module and the comprehensive calculation module are both electrically connected to the input end of the output module, and the output end of the output module is electrically connected to the input end of the peristaltic pump.

[0016] Preferably, the outer wall of the discharge pipe at the bottom of the chromatography column is provided with a control valve, the inner wall of the chromatography column is provided with a lining assembly, the lining assembly includes lining coatings arranged at intervals, a filling layer is provided on the opposite side of the lining coating, and the bottom end of the screen is provided with a placement block for supporting the screen, and one end of the placement block is fixedly connected to the inner wall of the chromatography column.

[0017] Technical effects and advantages of this utility model:

[0018] The utility model utilizes the design of a screen, a material level sensor, a controller, an electronic scale and a conveying component. The screen can be used to perform multi-stage filtration on the conveyed material, thereby gradually screening out impurities in the material and improving the purity of the product. At the same time, in conjunction with the setting of a peristaltic pump and an electronic scale, the material transmission speed can be controlled and adjusted, thereby achieving precise control of the feed, improving the separation effect, and reducing unnecessary solvent consumption and waste liquid generation. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic diagram of the overall three-dimensional structure of the utility model.

[0020] Figure 2 This is a schematic diagram of the cross-sectional structure of the chromatography column of the present utility model.

[0021] Figure 3 For this utility model Figure 2 A is a schematic diagram of the enlarged structure.

[0022] Figure 4 This is the framework of the control system of this utility model.

[0023] In the figure: 1. Storage box; 2. Chromatography column; 3. Conveying assembly; 31. Peristaltic pump; 32. Conveying pipe; 33. Flow sensor; 4. Level sensor; 5. Electronic scale; 6. Controller; 7. Screen; 8. Control valve; 9. Lining assembly; 91. Lining coating; 92. Filling layer; 10. Placement block. DETAILED DESCRIPTION

[0024] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0025] The utility model provides Figure 1-4 The high-efficiency chromatographic separation and purification equipment for imidacloprid technical drug shown includes a storage box 1 and a chromatography column 2. The storage box 1 is used to store the drug, and the chromatography column 2 is used to purify the drug. The storage box 1 is arranged on one side of the chromatography column 2, and also includes:

[0026] The conveying component 3 is used to convey the medicine inside the storage box 1 to the inside of the chromatography column 2;

[0027] The material level sensor 4 is used to monitor the position of the medicine inside the storage box 1;

[0028] An electronic scale 5, which is used to monitor the weight of the medicine inside the storage box 1;

[0029] The controller 6 is used to control the operation of the conveying component 3;

[0030] The sieve 7 is used for screening and filtering the medicine, and the sieve 7 is arranged inside the chromatography column 2.

[0031] Specifically, the conveying component 3 includes a peristaltic pump 31 and a conveying pipe 32. One end of the conveying pipe 32 extends into the interior of the material storage box 1, and the other end of the conveying pipe 32 is connected to the top of the chromatography column 2. The conveying pipe 32 is sleeved on the output end of the peristaltic pump 31. The peristaltic pump 31 is used to transport the material inside the conveying pipe 32. The input end of the peristaltic pump 31 is electrically connected to the output end of the controller 6. The outer wall of one end of the conveying pipe 32 is sleeved with a flow sensor 33. The flow sensor 33 is used to monitor the size of the material transmission flow inside the conveying pipe 32. The output end of the flow sensor 33 is electrically connected to the input end of the controller 6.

[0032] Furthermore, the peristaltic pump 31 is an existing model BT100L flow intelligent peristaltic pump. The peristaltic pump 31 controls the feeding speed between 0.1-5 ml / min. The delivery tube 32 is inserted into the output end of the peristaltic pump 31. The material inside the delivery tube 32 is transmitted through the extrusion movement of the output end of the peristaltic pump 31. The flow sensor 33 is an existing HYLL-013 intelligent electromagnetic flow sensor, which monitors the flow rate of the material in the delivery tube 32 in real time.

[0033] Specifically, the back of the material level sensor 4 is fixedly connected to the front of the storage box 1, the output end of the material level sensor 4 is electrically connected to the input end of the controller 6, the electronic scale 5 is arranged at the bottom end of the storage box 1, and the output end of the electronic scale 5 is electrically connected to the input end of the controller 6. A control system is arranged inside the controller 6, and the control system includes an input module, a judgment module, a comprehensive calculation module and an output module. The input end of the input module is electrically connected to the flow sensor 33, the material level sensor 4 and the output end of the electronic scale 5 respectively, and the output end of the input module is electrically connected to the input end of the judgment module and the comprehensive calculation module respectively. The output ends of the judgment module and the comprehensive calculation module are both electrically connected to the input end of the output module, and the output end of the output module is electrically connected to the input end of the peristaltic pump 31.

[0034] Furthermore, the material level sensor 4 is an existing XKC-Y28 non-contact liquid level sensor. The material level sensor 4 is bonded and fixed to the contact portion of the storage box 1 by gluing. The storage box 1 adopts a transparent plastic box body. The electronic scale 5 is an existing electronic weighing scale. The storage box 1 is placed on the scale plate of the electronic scale 5. When the output end of the peristaltic pump 31 is in operation, the material is transmitted in the conveying pipe 32. The data of the electronic scale 5 and the flow sensor 33 will be transmitted to the input module of the controller 6 control system through the wire. The input module then transmits the signal to the comprehensive calculation module, and the flow rate can be measured through the flow sensor 33. Control, the numerical value of the feed amount can be obtained through the electronic scale 5, and then after comprehensive calculation, the feed speed and amount can be regulated respectively, and the rotation of the peristaltic pump 31 can be adjusted, so as to achieve the effect of accurately controlling the feed speed and amount. When the material liquid level inside the storage box 1 is lower than the monitoring position of the material level sensor 4, the material level sensor 4 continuously sends a signal to the input module of the control system, and the input module sends a signal to the judgment module. The judgment module judges that the signal source is the material level sensor 4, and after the signal continues to output for 1-2s, the judgment module outputs a signal to the output module, and the output module outputs a signal to the peristaltic pump 31 to stop the peristaltic pump 31.

[0035] Specifically, the outer wall of the discharge pipe at the bottom of the chromatography column 2 is provided with a control valve 8, the interior of the chromatography column 2 is provided with a screen 7 for screening materials, the inner wall of the chromatography column 2 is provided with a lining assembly 9, the lining assembly 9 includes an inner lining coating 91 arranged at intervals, and a filling layer 92 is provided on the opposite side of the inner lining coating 91. The bottom end of the screen 7 is provided with a placement block 10 for supporting the screen 7, and one end of the placement block 10 is fixedly connected to the inner wall of the chromatography column 2.

[0036] Furthermore, the chromatography column 2 is made of stainless steel, the inner lining coating 91 is made of a high molecular polymer coating, and the filling layer 92 is made of a silica gel matrix chromatography medium with high selectivity and large adsorption capacity. There are multiple screens 7, and the screen apertures of the screens 7 decrease in equal amounts from top to bottom. The aperture variation range is from 0.45 microns to 0.22 microns. Through the gradual screening of multiple screens 7, impurities in the material can be efficiently removed. At least three placement blocks 10 are set at the bottom of a screen 7, and the three placement blocks 10 are set in a ring with equal intervals, thereby providing a good support for the screen 7.

[0037] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent replacements for some of the technical features therein. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A high-efficiency chromatographic separation and purification device for imidacloprid original medicine, comprising a storage box (1) and a chromatography column (2), wherein the storage box (1) is used for storing the medicine, and the chromatography column (2) is used for purifying the medicine, and the storage box (1) is arranged on one side of the chromatography column (2), characterized in that: Also includes: A conveying assembly (3), wherein the conveying assembly (3) is used to convey the medicine inside the storage box (1) to the inside of the chromatography column (2); A material level sensor (4), the material level sensor (4) is used to monitor the position of the medicine inside the storage box (1); An electronic scale (5), the electronic scale (5) being used to monitor the weight of the medicine inside the storage box (1); A controller (6), the controller (6) being used to control the operation of the conveying assembly (3); A sieve (7) is used for screening and filtering medicines, and the sieve (7) is arranged inside the chromatography column (2).

2. The high-efficiency chromatography separation and purification of imidacloprid original medicine equipment according to claim 1, characterized in that The conveying assembly (3) includes a peristaltic pump (31) and a conveying pipe (32), one end of the conveying pipe (32) extends into the interior of the storage box (1), the other end of the conveying pipe (32) is connected to the top end of the chromatography column (2), and the conveying pipe (32) is sleeved on the output end of the peristaltic pump (31).

3. The high efficiency chromatography separation and purification of imidacloprid original medicine equipment according to claim 2, characterized in that, The peristaltic pump (31) is used to transport the material inside the delivery pipe (32), and the input end of the peristaltic pump (31) is electrically connected to the output end of the controller (6).

4. The high-efficiency chromatography separation and purification of imidacloprid original medicine equipment according to claim 3, characterized in that A flow sensor (33) is provided on the outer wall of one end of the delivery pipe (32). The flow sensor (33) is used to monitor the flow rate of the material transported inside the delivery pipe (32). The output end of the flow sensor (33) is electrically connected to the input end of the controller (6).

5. The high-efficiency chromatography separation and purification of imidacloprid original medicine equipment according to claim 1, characterized in that The back of the material level sensor (4) is fixedly connected to the front of the material storage box (1), and the output end of the material level sensor (4) is electrically connected to the input end of the controller (6).

6. The high-efficiency chromatography separation and purification of imidacloprid original medicine equipment according to claim 1, characterized in that The electronic scale (5) is arranged at the bottom end of the storage box (1), and the output end of the electronic scale (5) is electrically connected to the input end of the controller (6).

7. The high-efficiency chromatography separation and purification of imidacloprid original medicine equipment according to claim 2, characterized in that The controller (6) is internally provided with a control system, which includes an input module, a judgment module, a comprehensive calculation module and an output module. The input end of the input module is electrically connected to the output ends of the flow sensor (33), the material level sensor (4) and the electronic scale (5), respectively. The output end of the input module is electrically connected to the input ends of the judgment module and the comprehensive calculation module, respectively. The output ends of the judgment module and the comprehensive calculation module are both electrically connected to the input end of the output module. The output end of the output module is electrically connected to the input end of the peristaltic pump (31).

8. The high-efficiency chromatography separation and purification of imidacloprid original medicine equipment according to claim 1, characterized in that The outer wall of the discharge pipe at the bottom of the chromatography column (2) is provided with a control valve (8), the inner wall of the chromatography column (2) is provided with a lining assembly (9), the lining assembly (9) includes lining coatings (91) arranged at intervals, and a filling layer (92) is provided on the opposite side of the lining coating (91), and the bottom end of the screen (7) is provided with a placement block (10) for supporting the screen (7), and one end of the placement block (10) is fixedly connected to the inner wall of the chromatography column (2).

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