Temperature control device for cell centrifugal device and cell centrifugal device
Through the combination of thermal conductivity and heat dissipation components, rapid uniformity and efficient cooling of the temperature in the centrifuge cavity are achieved, and the problems of uneven temperature and low cooling rate in the prior art are solved, thereby protecting the cell culture environment.
Patent Information
- Application Number
- CN202422383094.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-29
- Publication Date
- 2025-08-19
- Estimated Expiration
- 2034-09-29
AI Technical Summary
The temperature in the cavity of existing centrifuges is uneven and the cooling rate is low, so automatic monitoring and heating cannot be achieved, which affects cell culture.
Thermal conduction and heat dissipation components are adopted, including heating parts, refrigeration parts, blower parts and temperature probes, and automatic temperature control is achieved through the controller to ensure temperature uniformity and rapid cooling.
It achieves rapid uniformity and efficient cooling of the temperature in the centrifuge cavity, protects the cell culture environment and avoids adverse effects.
Smart Images

Figure CN223234054U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to a temperature control device for a cell centrifuge device and the cell centrifuge device. Background Art
[0002] To ensure normal cell culture, existing centrifuges require a suitable temperature environment. However, the heating components installed in the cavity of existing centrifuges are heating pads, heating nets or heating plates. The problems are: the temperature in the entire cavity of the centrifuge is uneven, and the uniformity of heating and the efficiency of heat dissipation are not taken into account; when the temperature is too high, it can only cool naturally, and the cooling rate is low; automatic monitoring and automatic heating cannot be achieved, which has a great impact on cell culture. Utility Model Content
[0003] The purpose of the utility model is to provide a temperature control device for a cell centrifuge device and a cell centrifuge device.
[0004] In order to achieve the above purpose, a technical solution adopted by the utility model is:
[0005] A temperature control device for a cell centrifuge device, comprising:
[0006] A housing having a receiving space;
[0007] A heat-conducting component is disposed in the housing space of the housing, and includes a heating element, a cooling element, and an air blowing element. The heating element is used to provide heat, the cooling element is used to cool, and the air blowing element is used to blow air toward the heating element, and to blow air cooled by the cooling element into the housing space of the housing.
[0008] A heat dissipation assembly, comprising a heat dissipation cavity and an air induction member, wherein the heat dissipation cavity is connected to the housing and has a heat dissipation air duct. An opening that is in communication with the heat dissipation air duct is formed on a side of the heat dissipation cavity away from the housing, the opening being in communication with the atmosphere, and the air induction member being located within the heat dissipation air duct.
[0009] A temperature probe is located in the accommodating space of the shell and is used to detect the temperature inside the shell.
[0010] According to some implementation aspects of the present invention, the heat dissipation cavity includes a first cavity, a second cavity and a third cavity which are connected in sequence, the first cavity and the third cavity are respectively arranged at the upper end and the lower end of the second cavity, the end of the first cavity away from the second cavity is provided with an opening connected to the atmosphere, the second cavity is connected to the shell, the end of the third cavity away from the second cavity is provided with an opening connected to the atmosphere, and the air inducing member is located in the third cavity.
[0011] According to some implementation aspects of the present invention, a heat sink is provided in the second cavity, and the heat sink is made of metal.
[0012] According to some implementation aspects of the present invention, the second cavity includes a substrate and a cover, the substrate is connected to the shell, the cover is arranged on the substrate, and the cover is in a straight U shape.
[0013] According to some implementation aspects of the present invention, a receiving groove is provided on the side of the substrate facing the shell, a heat conducting strip is provided in the receiving groove, and the heat conducting strip is made of metal.
[0014] According to some implementation aspects of the present invention, the heat-conducting component also includes a heat-conducting cavity, which has an accommodating space. The accommodating space is a space with both the upper and lower sides open and the other sides closed. The heating element is located in the heat-conducting cavity, the blowing element is located on the upper side of the heat-conducting cavity, and the refrigeration element is located outside the heat-conducting cavity.
[0015] The heat conduction cavity comprises a support plate and a support seat, the support seat is in a straight U shape, and the support plate and the support seat are connected.
[0016] According to some implementation aspects of the present invention, a heat conducting sheet is further provided in the heat conducting cavity, and the heat conducting sheet is made of metal material; a temperature protector is also provided in the heat conducting cavity.
[0017] According to some implementation aspects of the present invention, a plurality of the heat-conducting sheets are provided, and the plurality of the heat-conducting sheets are arranged in parallel, with a gap maintained between two adjacent heat-conducting sheets; a mounting portion is provided on a side of the outermost heat-conducting sheet away from the adjacent heat-conducting sheets, and a through hole is provided on the mounting portion along its extension direction, and the heating element is arranged in the through hole.
[0018] According to some implementation aspects of the present invention, the heat-conducting assembly further includes a fixing platform and a connecting plate, the connecting plate being arranged on the upper side of the heat-conducting cavity, the fixing seat being arranged on the side of the connecting plate away from the heat-conducting cavity, and the fixing platform being used to fix the blowing member.
[0019] According to some implementation aspects of the present invention, a fixing seat is provided in the shell, and the temperature probe is provided on the fixing seat. The fixing seat includes a seat body and a boss protruding from one side of the seat body. The seat body is square ring-shaped, and a through hole is provided on the boss for the temperature probe to pass through.
[0020] According to some implementation aspects of the present invention, the device further includes a controller, and the controller is connected to the heat conduction component, the heat dissipation component, and the temperature probe.
[0021] Another technical solution adopted in this utility model is:
[0022] A cell centrifugal device comprises the temperature control device for the cell centrifugal device and a centrifuge, wherein the centrifuge is located in the accommodating space of the shell.
[0023] Due to the application of the above technical solution, the utility model has the following advantages compared with the prior art:
[0024] The cell centrifuge device provided by the utility model is advantageous in that the heat conducting component is provided, so that the heat or cooling air is diffused over a large area in the accommodation space of the shell, so that the temperature in the shell can be increased or decreased relatively quickly, the temperature in the shell is relatively uniform, and the heat dissipation efficiency is high; and the heat dissipation component is provided, so that the temperature in the shell can be decreased relatively quickly, and the cooling efficiency is high. BRIEF DESCRIPTION OF THE DRAWINGS
[0025] Attachment Figure 1 This is a structural diagram from a first perspective of the temperature control device for a cell centrifuge device provided by the present invention;
[0026] Attachment Figure 2 A structural diagram of the temperature control device for a cell centrifuge provided by the present invention from a second perspective;
[0027] Attachment Figure 3 A structural diagram of the temperature control device for a cell centrifuge device provided by the present invention from a third perspective;
[0028] Attachment Figure 4 A structural diagram of the temperature control device for a cell centrifuge device provided by the present invention from a fourth perspective;
[0029] Attachment Figure 5 A structural diagram of the cell centrifuge device provided by the utility model;
[0030] Attachment Figure 6 A structural diagram of a heat-conducting component and a heat sink of a temperature control device for a cell centrifuge provided by the present invention;
[0031] Attachment Figure 7A structural diagram from a first perspective of a heat-conducting component of a temperature control device for a cell centrifuge device provided by the present invention;
[0032] Attachment Figure 8 A structural diagram from a second perspective of a heat-conducting component of a temperature control device for a cell centrifuge device provided by the present invention;
[0033] Attachment Figure 9 This is a structural diagram from a first perspective of the heat conduction cavity of the temperature control device for a cell centrifuge provided by the present invention;
[0034] Attachment Figure 10 A structural diagram from a second perspective of the heat transfer cavity of the temperature control device for a cell centrifuge provided by the present invention;
[0035] Attachment Figure 11 A structural diagram from a third perspective of the heat transfer cavity of the temperature control device for a cell centrifuge provided by the present invention;
[0036] Attachment Figure 12 A structural diagram of a heat sink for a temperature control device of a cell centrifuge provided by the present invention;
[0037] Attachment Figure 13 A structural diagram of the heat sink and refrigeration components of the temperature control device for a cell centrifuge provided by the present invention;
[0038] Attachment Figure 14 A structural diagram of an air induction component of a temperature control device for a cell centrifuge provided by the present invention;
[0039] Attachment Figure 15 A structural diagram of a fixing seat of a temperature control device for a cell centrifuge provided by the present invention;
[0040] Attachment Figure 16 This is a structural diagram of the heating element of the temperature control device for the cell centrifuge device provided by the present invention.
[0041] In the above attached figures:
[0042] 1-heat conducting assembly, 11-heating element, 12-cooling element, 13-blowing element, 14-support plate, 15-first plate, 16-second plate, 17-heat conducting sheet, 18-fixing platform, 19-connecting plate, 20-mounting part;
[0043] 2-heat dissipation cavity, 21-first part, 22-second part, 23-base plate, 24-cover, 25-first section, 26-second section;
[0044] 3-air induction member; 4-heat sink; 5-heat conducting strip; 6-fixing seat, 61-seat body, 62-boss;
[0045] 7-temperature probe; 8-temperature protector; 9-housing; 10-centrifuge, 20-infrared temperature sensor. DETAILED DESCRIPTION
[0046] The following is a clear and complete description of the technical solution of the present invention in conjunction with the accompanying drawings. Obviously, the embodiments described are only some of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making any creative efforts are within the scope of protection of the present invention.
[0047] In the description of this utility model, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating positions or relationships, are based on the positions or relationships shown in the accompanying drawings and are intended solely to facilitate the description of this utility model and simplify the description. They do not indicate or imply that the devices or components referred to must have a specific orientation, be constructed, or operate in a specific orientation. Therefore, they should not be construed as limitations on this utility model. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.
[0048] See also Figures 1 to 4 、 Figures 6 to 16 The temperature control device for a cell centrifuge device shown includes a housing 9, a heat conducting component 1, a heat dissipating component, and a temperature probe 7, wherein:
[0049] The housing 9 has a receiving space, and includes a housing body and a cover body provided on the open side of the housing body. The temperature probe 7 is located in the receiving space of the housing 9 and is used to detect the temperature in the receiving space of the housing 9.
[0050] The heat conduction component 1 is arranged in the storage space of the shell 9. The heat conduction component 1 includes a heating element 11, a cooling element 12, and a blowing element 13. The heating element 11 is used to provide heat, the cooling element 12 is used for cooling, and the blowing element 13 is used to blow air toward the heating element 11 to conduct heat into the storage space of the shell 9 and to blow the air cooled by the cooling element 12 into the storage space of the shell 9. This is conducive to the large-area diffusion of heat or cooled air in the storage space of the shell 9, so that the temperature in the shell 9 can be increased or decreased more quickly, and the temperature in the shell 9 is more uniform. The air outlet side of the blowing element 13 is preferably facing the heating element 11 to form convection, blowing hot air to the entire shell 9, making the temperature in the shell 9 more uniform.
[0051] The heat-conducting assembly 1 also includes a heat-conducting cavity, which is connected from top to bottom and surrounded on all sides, that is, the heat-conducting cavity has an accommodating space, which is a space with both the upper and lower sides open and the other sides closed. The heating element 11 is located in the heat-conducting cavity, the blowing element 13 is located on the upper side of the heat-conducting cavity, and the cooling element 12 is located outside the heat-conducting cavity.
[0052] In some embodiments, the heat conduction chamber includes a support plate 14 and a support. The support plate 14 is rectangular in shape. The support includes a first plate 15 and two second plates 16. The two second plates 16 are respectively arranged at opposite ends of the same side of the first plate 15, and the first plate 15 is perpendicular to the second plate 16. The two second plates 16 are connected to the first plate 15 in a straight U-shape. The support plate 14 is arranged on the open side of the support. The support plate 14 is connected to the first plate 15. The support plate 14 and the support are connected to form a space with both the upper and lower sides open and the other sides closed. In this example, the support plate 14 is detachably connected to the first plate 15, such as by fasteners (bolt and nut assemblies), which facilitates the removal of the support plate 14 to install the heat conducting plate 17, the heater 11, and the temperature protector 8.
[0053] See also Figure 9-10 A heat conducting sheet 17 is also provided in the heat conducting cavity. The heat conducting sheet 17 is made of metal and is connected to the first plate 15. The heat conducting sheet 17 extends in the vertical direction. There are multiple heat conducting sheets 17, which are arranged in parallel with each other, and a gap is maintained between adjacent heat conducting sheets 17. A mounting portion 20 is provided on the side of the outermost heat conducting sheet 17 away from the adjacent heat conducting sheet 17. The mounting portion 20 has a through hole along its extension direction. The heating element 11 is provided in the through hole. The heating element 11 is a heating rod that can be electrically heated and is cylindrical. The heat conducting sheet 17 is in the shape of an elongated strip, and the mounting portion 20 is in the shape of a rectangular parallelepiped. It is preferred to provide two mounting portions 20 and two heating elements 11.
[0054] A temperature protector 8 is also provided in the heat conduction cavity to prevent the temperature from being too high.
[0055] The refrigeration element 12 in this example is preferably a semiconductor refrigeration chip, model HT064062, and its operating temperature range is -20 to 55°C.
[0056] See also Figure 7-8The heat-conducting component 1 also includes a fixing platform 18 and a connecting plate 19. The connecting plate 19 is arranged on the upper side of the heat-conducting cavity, and the fixing seat 6 is arranged on the side of the connecting plate 19 away from the heat-conducting cavity. The fixing platform 18 is used to fix the blowing member 13. The connecting plate 19 is in a straight U-shape, and the opposite ends of the connecting plate 19 are respectively connected to the two second plates 16. There are multiple fixing platforms 18, and there are multiple blowing members 13. The blowing members 13 correspond to the fixing platforms 18 one by one. There are openings on the fixing platform 18 and the connecting plate 19. The openings are connected with the accommodating space of the heat-conducting cavity. The heat generated by the heating element 11 is blown out to the accommodating space of the shell 9 through the blowing member 13, thereby achieving a large-area temperature increase in the shell 9.
[0057] In this example, the heat dissipation assembly includes a heat dissipation cavity 2 and an air induction member 3. The heat dissipation cavity 2 is connected to the shell 9. The heat dissipation cavity 2 has a heat dissipation air duct. The heat dissipation cavity 2 is provided with an opening that is connected to the heat dissipation air duct on the side away from the shell 9. The opening is connected to the atmosphere, and the air induction member 3 is located in the heat dissipation air duct. When the temperature inside the shell 9 is higher than the target temperature, the air induction member 3 is turned on, and the controller outputs a cooling command to control the relay system to drive the refrigeration member 12 to work for cooling, and opens the air induction member 3 of the external heat dissipation air duct to dissipate heat to the outside. At the same time, the blowing member 13 inside the shell 9 works to blow cold air to the entire shell 9 until the temperature inside the shell 9 reaches the target temperature and stops. When the temperature inside the shell 9 is lower than the target temperature, the air induction member 3 does not work.
[0058] See also Figure 1-5 In some embodiments, the heat dissipation cavity 2 includes a first cavity, a second cavity, and a third cavity that are connected to each other. The first cavity and the third cavity are respectively arranged at the upper end and the lower end of the second cavity. An opening communicating with the atmosphere is opened at one end of the first cavity away from the second cavity. The second cavity is connected to the shell 9. An opening communicating with the atmosphere is opened at one end of the third cavity away from the second cavity. The air inducing member 3 is located in the third cavity, and the opening of the third cavity faces the supporting ground.
[0059] The second cavity is surrounded on all sides and penetrated in the vertical direction. The third cavity includes a first section 25 and a second section 26 that are connected in sequence. The first section 25 is located above the second section 26. The first section 25 is connected to the second cavity. The first section 25 is narrow at the top and wide at the bottom, that is, the width of the first section 25 gradually increases from its upper end to the lower end. The second section 26 is surrounded on all sides and penetrated in the vertical direction. The air inducing member 3 is preferably located in the second section 26.
[0060] See also Figure 3 The first cavity includes a first part 21 and a second part 22 that are connected. The first part 21 and the second part 22 are horizontally arranged (such as left and right arrangements). The first part 21 is connected to the second cavity. The side cross-section of the first part 21 is trapezoidal, and the second part 22 is surrounded on all four sides and penetrates in the left and right directions.
[0061] See also Figure 3-4The second cavity includes a substrate 23 and a cover 24. The substrate 23 is connected to the shell 9. The substrate 23 serves as a side wall of the shell 9, and one side of the substrate 23 faces the inside of the shell 9; the cover 24 is connected to the substrate 23. The cover 24 is a straight U-shape. The substrate 23 and the cover 24 are connected to form a cavity that is enclosed on all sides and penetrates in the up and down directions. The other side of the substrate 23 faces the cavity.
[0062] In a preferred embodiment, a heat sink 4 is provided in the second cavity and is visible from the opening of the first cavity. The heat sink 4 is made of metal and has the advantage of dissipating heat within the housing 9. Preferably, multiple heat sinks 4 are provided, and the multiple heat sinks 4 are arranged in parallel with gaps between adjacent heat sinks 4.
[0063] In a preferred embodiment, a receiving groove is provided on the side of the base plate 23 facing the housing 9. A heat conducting strip 5 is disposed within the receiving groove. The heat conducting strip 5 is made of a metal material (preferably copper) and is disposed opposite (or in contact with) the refrigeration element 12. The provision of the heat conducting strip 5 facilitates the transfer of heat from the housing 9 to the outside when the temperature inside the housing 9 is high. Preferably, multiple receiving grooves are provided, and multiple heat sinks 4 are provided, with each receiving groove corresponding to each heat sink 4. The heat conducting strip 5 is disposed vertically and may be oval in shape.
[0064] The device also includes a controller, which is connected to the heat conduction component 1, the heat dissipation component, and the temperature probe 7.
[0065] See also Figure 15 A fixing base 6 is disposed within the housing 9, and a temperature probe 7 is mounted on the fixing base 6. The fixing base 6 comprises a base body 61 and a boss 62 protruding from one side of the base body 61. The base body 61 is square and annular, with a central hole defined in the middle thereof, and a through-hole for the temperature probe 7 to pass through defined on the boss 62. Two bosses 62 are provided, one at the upper end and the other at the lower end of the same side of the base body 61. Opposite ends of the temperature probe 7 are mounted on the two bosses 62.
[0066] The device also includes an infrared temperature sensor 20 and an alarm. Both the infrared temperature sensor 20 and the alarm are connected to the controller. The infrared temperature sensor is responsible for monitoring the temperature inside the shell 9 and transmitting the temperature result to the controller in real time. When the temperature is too high or too low, the alarm will work and the power supply can be cut off.
[0067] The temperature control principle of the cell centrifuge device in this example is as follows: the shell 9 is sealed, and the blowing member 13 inside the shell 9 is always powered on (on when powered on, off when powered off) to ensure that the air in the shell 9 flows so that the temperature is uniform. The target temperature is set on the controller, and then the controller controls the relay system to drive cooling or heating; the temperature probe 7 collects the temperature in the shell 9 in real time and transmits it to the controller. When the temperature in the current shell 9 is higher than the target temperature, the controller outputs a cooling command to control the relay system to drive the cooling member 12 to work for cooling, and opens the air induction member 3 in the heat dissipation chamber 2 to dissipate heat to the outside. At the same time, the blowing member 13 inside the shell 9 blows cold air to the entire shell 9 until the temperature in the shell 9 reaches the target temperature and stops; when the temperature in the current shell 9 is lower than the target temperature, the controller outputs a heating command to control the relay system to drive the heating member 11 to work, and the blowing member 13 inside the shell 9 blows hot air to the entire shell 9 until the temperature in the shell 9 reaches the target temperature and stops (the air induction member 3 does not work during this process). In addition, in the case of abnormal heating, the temperature switch disconnects the heating element 11 to prevent further heating when the temperature reaches its own limit temperature; in addition, the temperature probe 7 monitors the temperature inside the shell 9 and transmits the temperature detection results to the controller in real time, and controls the heat conduction component and the heat dissipation component according to the detection results.
[0068] The advantages of the temperature control device for the cell centrifuge device in this example are: by providing a heat conducting component and a heat dissipating component, temperature acquisition is more accurate, temperature control is more precise, protective measures are more complete, and there is no adverse effect on cell culture.
[0069] In another embodiment, a cell centrifuge device is provided, which includes a temperature control device for the cell centrifuge device and a centrifuge 10. The centrifuge 10 is located in the accommodating space of the shell 9. The centrifuge 10 is used for centrifugal processing of cells. The centrifuge 10 is a technical device well known to those skilled in the art.
[0070] The above embodiments are intended only to illustrate the technical concepts and features of the present invention. Their purpose is to enable those familiar with the art to understand the contents of the present invention and implement them accordingly. They are not intended to limit the scope of protection of the present invention. Any equivalent changes or modifications based on the spirit of the present invention are intended to be included in the scope of protection of the present invention.
Claims
1. A temperature control device for a cell centrifuge, characterized in that: include: A housing having a receiving space; A heat-conducting component is disposed in the housing space of the housing, and includes a heating element, a cooling element, and an air blowing element. The heating element is used to provide heat, the cooling element is used to cool, and the air blowing element is used to blow air toward the heating element, and to blow air cooled by the cooling element into the housing space of the housing. A heat dissipation assembly, comprising a heat dissipation cavity and an air induction member, wherein the heat dissipation cavity is connected to the housing and has a heat dissipation air duct. An opening that is in communication with the heat dissipation air duct is formed on a side of the heat dissipation cavity away from the housing, the opening being in communication with the atmosphere, and the air induction member being located within the heat dissipation air duct. A temperature probe is located in the accommodating space of the shell and is used to detect the temperature inside the shell.
2. The temperature control device for a cell centrifuge according to claim 1, characterized in that: The heat dissipation cavity includes a first cavity, a second cavity and a third cavity which are connected in sequence. The first cavity and the third cavity are respectively arranged at the upper end and the lower end of the second cavity. The end of the first cavity away from the second cavity is provided with an opening connected to the atmosphere. The second cavity is connected to the shell. The end of the third cavity away from the second cavity is provided with an opening connected to the atmosphere. The air inducing member is located in the third cavity.
3. The temperature control device for a cell centrifuge according to claim 2, characterized in that: The second cavity is provided with a heat sink, and the heat sink is made of metal.
4. The temperature control device for a cell centrifuge according to claim 3, characterized in that: The second cavity comprises a base plate and a cover. The base plate is connected to the shell. The cover is arranged on the base plate and is in a straight U shape.
5. The temperature control device for a cell centrifuge according to claim 4, characterized in that: The substrate is provided with a receiving groove on a side facing the shell, a heat conducting strip is provided in the receiving groove, and the heat conducting strip is made of metal material.
6. The temperature control device for a cell centrifuge according to claim 1, characterized in that: The heat-conducting component also includes a heat-conducting cavity, which has an accommodating space. The accommodating space is a space with both the upper and lower sides open and the other sides closed. The heating element is located in the heat-conducting cavity, the blowing element is located on the upper side of the heat-conducting cavity, and the cooling element is located outside the heat-conducting cavity.
7. The temperature control device for a cell centrifuge according to claim 6, characterized in that: A heat conducting sheet is also provided in the heat conducting cavity, and the heat conducting sheet is made of metal material; a temperature protector is also provided in the heat conducting cavity.
8. The temperature control device for a cell centrifuge according to claim 7, characterized in that: There are multiple heat-conducting sheets, which are arranged in parallel with each other, and a gap is maintained between two adjacent heat-conducting sheets; a mounting portion is provided on the side of the outermost heat-conducting sheet away from the adjacent heat-conducting sheet, and a through hole is provided on the mounting portion along its extension direction, and the heating element is arranged in the through hole.
9. The temperature control device for a cell centrifuge according to claim 1, characterized in that: A fixing seat is provided in the shell, and the temperature probe is provided on the fixing seat. The fixing seat includes a seat body and a boss protruding from one side of the seat body. The seat body is square ring-shaped, and a through hole for the temperature probe to pass through is opened on the boss.
10. A cell centrifuge device, characterized in that: The device comprises the temperature control device for a cell centrifuge according to any one of claims 1 to 9 and a centrifuge, wherein the centrifuge is located in the accommodation space of the shell.