Tumor electric field treatment device and electrode patch thereof

Abstract

The utility model provides a tumor electric field treatment device and an electrode patch thereof, the electrode patch comprises an electrode array and one or more pasting pieces, and the electrode array is provided with a plurality of electrode units, a plurality of connecting parts for connecting two adjacent electrode units and a wiring part. The pasting piece is provided with a first layer covering the electrode array and a second layer used for being pasted to the body surface of a patient, and the viscosity of the first layer is larger than that of the second layer. According to the tumor electric field treatment device and the electrode patch thereof, the stickiness of the first layer covering the electrode array is higher than that of the second layer attached to the body surface of the patient, the electrode array can be tightly attached to the body surface of the patient without a backing, and the heat dissipation effect of the electrode patch attached to the body surface of the patient can be improved; and the sticking piece can be prevented from being separated from the electrode array when the electrode patch is removed from the body surface of the patient.

Description

Technical Field

[0001] The present application relates to a tumor electric field treatment device and an electrode patch thereof, belonging to the technical field of medical devices. Background Art

[0002] Medium-frequency alternating electric field therapy has been shown to be an effective method for tumor treatment. It can interfere with the mitotic process of cancer cells and induce apoptosis, making it suitable for treating tumors. Tumor electric field therapy devices typically include an electric field generator, an adapter, and multiple pairs of electrode patches. The electric field generator generates an alternating electrical signal, which is transmitted to the electrode patches via the adapter. The electrode patches are applied in pairs to the skin surfaces of opposite sides of the subject, applying an alternating current signal between each pair of electrode patches, thereby applying a tumor-treating electric field to the target area.

[0003] The electrode patch usually includes a backing, an electrode array, several adhesive parts and release paper. The backing is usually made of non-woven fabric. The electrode array is adhered to the backing and is provided with several electrode units and a temperature sensor. The adhesive part is usually a conductive gel and covers the electrode array. The release paper is wrapped around the outside of the adhesive part and the backing to prevent the adhesive part and the backing from being contaminated. When in use, tear off the release paper, apply the exposed surface of the adhesive part to the patient's body surface, and the patient can receive electric field therapy. During the electric field therapy process, the electrode unit will heat up. Although the backing covering the electrode unit from the outside is made of breathable material, it will still affect the heat dissipation of the electrode unit. In order to avoid low-temperature burns to the patient, the application of the electric field will be suspended or reduced in efficiency after the temperature of the electrode unit exceeds the safety threshold, affecting the effect of the electric field therapy.

[0004] Therefore, it is indeed necessary to provide an improved tumor electric field treatment device and electrode patch thereof to overcome the problems currently existing in existing tumor electric field treatment devices and electrode patches. Utility Model Content

[0005] The present application provides a tumor electric field therapy device and an electrode patch thereof, which can improve heat dissipation and can be easily removed from the patient's body surface.

[0006] The present application can be implemented through the following technical solution: an electrode patch, comprising an electrode array and one or more adhesive parts, wherein the electrode array is provided with a plurality of electrode units, a plurality of connecting parts and wiring parts connecting two adjacent electrode units, and the adhesive part is provided with a first layer covering the electrode array and a second layer for being applied to the patient's body surface, wherein the viscosity of the first layer is greater than the viscosity of the second layer.

[0007] Furthermore, the electrode array has a side surface away from the adhesive member and exposed to the outside during use.

[0008] Furthermore, the first layer and the second layer are composed of the same components, which include at least one component that affects viscosity, and the content ratio of the at least one component that affects viscosity in the first layer is greater than the content ratio in the second layer.

[0009] Furthermore, the first layer and the second layer have different components.

[0010] Furthermore, the adhesive member includes polyacrylic acid.

[0011] Furthermore, the adhesive includes magnesium hydroxide.

[0012] Furthermore, the electrode unit includes a substrate, a conductive sheet, an insulating layer and a dielectric layer. The insulating layer presses the conductive sheet onto the substrate, and the dielectric layer is laid on the insulating layer and the area where the conductive sheet is exposed from the insulating layer.

[0013] Furthermore, the electrode unit further includes an alloy layer, the alloy layer covers the dielectric layer, and the adhesive member covers the alloy layer.

[0014] Furthermore, the adhesive members cover the electrode units in a one-to-one correspondence.

[0015] The present application can be implemented through the following technical solution: A tumor electric field treatment device includes an electric field generator, an adapter and a plurality of the aforementioned electrode patches arranged in pairs.

[0016] The adhesive of the tumor electric field therapy device and its electrode patch of the present application covering the first layer of the electrode array has stronger viscosity than the second layer applied to the patient's body surface. This design can firmly apply the electrode array to the patient's body surface without a backing, and can improve the heat dissipation effect of the electrode patch applied to the patient's body surface. In addition, it can also prevent the adhesive from detaching from the electrode array when the electrode patch is removed from the patient's body surface.

[0017] It should be understood that the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a structural block diagram of the tumor electric field treatment device of this application;

[0019] Figure 2 is a three-dimensional assembly diagram of an electrode patch according to the first embodiment of the present application;

[0020] Figure 3 for Figure 2 Exploded three-dimensional diagram of the electrode patch;

[0021] Figure 4 for Figure 3A three-dimensional exploded view of the electrode array of the electrode patch;

[0022] Figure 5 For the Figure 2 A cross-sectional view of a single electrode unit taken along line AA in FIG.

[0023] Figure 6 is a perspective exploded view of an electrode patch according to a second embodiment of the present application;

[0024] Figure 7 is a perspective exploded view of an electrode patch according to a third embodiment of the present application;

[0025] Figure 8 is a perspective exploded view of an electrode patch according to a fourth embodiment of the present application;

[0026] Figure 9 for Figure 8 A plan view of the electrode patch in FIG;

[0027] Figure 10 for Figure 8 Another plan view of the electrode patch in which the dielectric layer and the alloy layer have not yet been provided;

[0028] Figure 11 For the Figure 9 A cross-sectional view of a single electrode unit obtained along line BB in FIG;

[0029] Figure 12 is a plan view of an electrode patch according to a fifth embodiment of the present application;

[0030] Figure 13 4 is a plan view of an electrode patch according to a sixth embodiment of the present application. DETAILED DESCRIPTION

[0031] Exemplary embodiments will be described in detail herein, examples of which are shown in the accompanying drawings. When the following description refers to the drawings, identical numbers in different drawings represent identical or similar elements unless otherwise indicated. The embodiments described in the following exemplary embodiments are not intended to represent all embodiments consistent with the present application. Instead, they are merely examples of electrode patches consistent with certain aspects of the present application, as detailed in the appended claims.

[0032] refer to Figure 1As shown, the tumor electric field treatment device 100 includes an electric field generator 10, an adapter 20, and several paired electrode patches. The adapter 20 electrically connects the electric field generator 10 to each electrode patch. The electric field generator 10 generates the alternating current (AC) signal required for treatment. The adapter 20 receives the AC signal output from the electric field generator 10 and transmits it to the electrode patches, generating a therapeutic electric field for treating the tumor between the same pair of electrode patches. During use, the electrode patches are applied to the patient's body surface corresponding to the tumor site to apply the therapeutic electric field to the tumor site. This application provides multiple embodiments of the electrode patches, which are described below.

[0033] refer to Figures 2 to 4 As shown, the electrode patch 30 in the first embodiment of the present application includes an electrode array 31, a plurality of support members 32, a plurality of adhesive members 33, and a conductive wire 34. The electrode array 31 includes a plurality of electrode units 311, a plurality of connecting portions 312 connecting two adjacent electrode units 311, and a connecting portion 313 extending laterally from a connecting portion 312. The connecting portion 313 is welded to the conductive wire 34.

[0034] The electrode array 31 is provided with 9 electrode units 311, which are arranged in a matrix of three rows and three columns. The adjacent two electrode units 311 in each row are connected by a corresponding connecting portion 312, and the adjacent two electrode units 311 in the middle column are connected by a corresponding connecting portion 312, forming a roughly "W"-shaped arrangement.

[0035] refer to Figure 4 , and combined with Figure 5As shown, the electrode unit 311 includes a main body 3111, an insulating plate 3112 provided on the side of the main body 3111 away from the patient's body surface, a dielectric element 3113 provided on the side of the main body 3111 facing the patient's body surface, and a temperature detection unit 3114 optionally provided on the main body 3111 and on the same side as the dielectric element 3113. The main body 3111, the insulating plate 3112, and the dielectric element 3113 are all circular sheet-like structures, and the centers of the three are located on the same straight line. A conductive disk 3115 is provided on the side of the main body 3111 facing the dielectric element 3113, which includes four conductive cores (not numbered) spaced apart and arranged in a centrally symmetrical shape. The dielectric element 3113 is made of a high dielectric constant material, which has the conductive property of blocking the conduction of direct current and allowing alternating current to pass through, thereby ensuring human safety. The conductive plate 3115 can be completely covered by the dielectric element 3113, facilitating soldering and electrical connection between the conductive plate 3115 and the dielectric element 3113. Sealant (unnumbered) is filled between the edge of the dielectric element 3113 and the conductive plate 3115 to protect the solder joints. The main bodies 3111, the connecting portions 312, and the wiring portions 313 collectively constitute the flexible circuit board 310 of the electrode array 31. The connecting portions 312 directly connect two adjacent main bodies 3111. The wiring portion 313 extends laterally from one of the connecting portions 312. The wiring portion 313 is provided with a plurality of gold fingers 3131. The wires 34 are soldered to the gold fingers 3131 of the wiring portion 313 to achieve electrical connection between the electrode array 31 and the wires 34.

[0036] The insulating plate 3112 is made of an insulating material, preferably an epoxy glass cloth laminate, and is adhered to the side of the main body 3111 away from the patient's body surface to provide support. The dielectric element 3113 is made of a high dielectric constant material, which has the conductive property of hindering the conduction of direct current and allowing alternating current to pass through, which can ensure the safety of the human body. It is preferably a ceramic sheet. The dielectric element 3113 is annular in structure, and a through-hole 3116 is provided at the center. The temperature detection unit 3114 is accommodated in the through-hole 3116 of the dielectric element 3113, and is used to monitor the temperature of the corresponding adhesive member 33, and further detect the skin temperature of the patient attached to the adhesive member 33 to avoid low-temperature burns. The specific number of temperature detection units 3114 can be set as needed. In this embodiment, there are 8 temperature detection units 3114, and only the middle electrode unit 311 is not set.

[0037] Back to Figure 3As shown, the support member 32 is made of foam material and is arranged in a ring shape around the outer periphery of the electrode units 311 in the same row. The support member 32 is flush with the top surface of the electrode unit 311. The adhesive member 33 covers the multiple electrode units 311 in the same row on the electrode array 31. The adhesive member 33 has double-sided adhesiveness. One side of the adhesive member 33 is adhered to the support member 32 and the upper surface of the electrode unit 311. The other side of the adhesive member 33 serves as a patch layer, which is applied to the patient's body surface to keep the skin surface moist and relieve local pressure. The adhesive member 33 is preferably a conductive gel. With the support of the support member 32, the adhesive member 33 has better adhesion to the patient's body surface. The electrode patch 30 is attached to the body surface corresponding to the patient's tumor site through the adhesive member 33, and an alternating electric field is applied to the patient's tumor site through the electrode array 31 to interfere with or prevent the mitosis of the patient's tumor cells, thereby achieving the purpose of treating the tumor.

[0038] Compared to traditional electrode patches, the electrode patch 30 of the present application eliminates the backing. That is, the side of the electrode array 31 not covered by the adhesive 33 is exposed during treatment. This improves the heat dissipation of the electrode patch 30 and extends the duration of continuous treatment. After treatment, the electrode patch 30 is removed from the patient's body. Without the constraints of the backing, the adhesive 33 can easily separate from the electrode array 31 during the removal of the electrode patch 30. To avoid this, the adhesive 33 of the electrode patch of the present application has a stronger adhesive property on the side attached to the electrode array 31 than on the other side attached to the patient's body. This ensures that the adhesive 33 and the electrode array 31 remain adhered together, allowing the adhesive 33 to be easily removed from the patient's body.

[0039] As previously mentioned, the adhesive member 33 is preferably a conductive gel. To achieve different adhesion on both sides, the adhesive member 33 can be divided into two layers. The layer used to adhere to the electrode array 31 is defined as the first layer 331, and the layer used to be applied to the patient's body surface is defined as the second layer 332. The first layer 331 has a stronger adhesion than the second layer 332. The two layers can have the same composition, and the stronger adhesion can be achieved by increasing the content of the component that increases adhesion in the first layer 331. The adhesive member 33 can also be composed of two layers with different components, as long as the first layer 331 has a stronger adhesion than the second layer 332. There are many types of conductive gels on the market, and they can all be used as adhesive members 33 for this application with slight adjustments. The following only describes one type of composition used to prepare the conductive gel and the method for preparing the conductive gel.

[0040] A composition for preparing a conductive gel comprises, by weight, 10.53% to 12.53% of a water-based polymer, 0.37% to 0.57% of a strong acid and strong base salt, 18.22% to 20.22% of a water-retaining agent, 10.53% to 12.53% of a gelling agent, and 0.03% to 0.05% of a modifier. The water-based polymer comprises one or more of polyvinyl alcohol, hydroxymethyl cellulose, and polyethylene glycol. The water-based polymer can improve the stability of the prepared conductive gel. The strong acid and strong base salt comprises one or more of NaCl, KCl, LiCl, K2SO4, and Na2SO4. The strong acid and strong base salt can impart improved ionic conductivity, stretchability, and tissue softness to the prepared conductive gel. The water-retaining agent comprises one or more of propylene glycol and glycerol. The gelling agent comprises one or more of polyacrylic acid, pectin, gelatin, carrageenan, agar, and gellan gum. The gelling agent includes polyacrylic acid, which can enhance the viscosity and water retention of the prepared conductive gel. The modifier includes one or more of magnesium hydroxide, aluminum hydroxide, sodium hydroxide, calcium hydroxide, calcium carbonate, and sodium carbonate. The modifier is primarily used to increase the mechanical strength and viscosity of the prepared conductive gel. The composition used to prepare the conductive gel also includes a dispersant.

[0041] A method for preparing a conductive gel comprises dissolving a composition for preparing the conductive gel in water and mixing the mixture at a preset temperature to obtain a mixture; and curing the mixture to obtain the conductive gel. The mixing step comprises: first dissolving a water-based polymer, a strong acid and strong base salt, and a water-retaining agent in water and mixing them to obtain a mixture intermediate; then adding a gelling agent and a modifier to the mixture intermediate and mixing them to obtain a mixture. This step-by-step mixing method reduces the amount of coated reaction raw materials, thereby improving the utilization rate of the various reaction raw materials. The preset temperature is 60-100°C, which facilitates the dissolution of the various reaction raw materials and facilitates the preparation of a uniformly mixed mixture. The mixing time during the preparation of the mixture intermediate is 3-9 hours; and the mixing time during the preparation of the mixture is 30-60 minutes. During the curing step, the treatment temperature is -30-0°C, which allows the curing process to proceed under suitable conditions, thereby obtaining a conductive gel with better curing performance.

[0042] The present application also provides a specific embodiment of the preparation method of the above-mentioned conductive gel: 11% of polyvinyl alcohol with a weight average molecular weight of 150,000, 0.45% of NaCl, and 19% of glycerol are dissolved in 45% of water, and stirred and mixed at 90°C for 6 hours to obtain a mixture intermediate; then, polyacrylic acid with a weight average molecular weight of 3,000, polyacrylic acid with a weight average molecular weight of 400,000, and 0.04% of magnesium hydroxide are added to the mixture intermediate, and stirred and mixed at 95°C for 45 minutes to obtain a mixture, wherein the mass ratio of the two weight average molecular weight polyacrylic acids is 1.5:0.7, and the total mass of the two is 11%; then, the mixture is placed at -20°C for 1 hour to obtain a conductive gel.

[0043] The components that affect the viscosity of the above-mentioned conductive gel mainly include the gelling agent polyacrylic acid and the modifier magnesium hydroxide. By changing the specific gravity of polyacrylic acid and magnesium hydroxide, conductive gels with different viscosities can be formed. Therefore, the above method can be used to prepare two conductive gels with different viscosities, which can then be stacked together to form the adhesive member 33 required by this application.

[0044] In other embodiments, the adhesive member 33 may also be a non-conductive gel. As long as the viscosity of the first layer attached to the electrode array is greater than the viscosity of the second layer attached to the patient's body surface, the electrode array 31 can be firmly attached to the patient's body surface during tumor electric field therapy, and when the electrode patch 30 needs to be replaced, the adhesive member 33 can be easily removed from the patient's body surface along with the electrode array 31, thereby preventing the adhesive member 33 from detaching from the electrode array 31.

[0045] It is understandable that the shape of the electrode patch 30 of the present application can be adjusted. Specifically, the shape, number, matrix arrangement, etc. of the electrode units 311 of the electrode array 31 can be changed and adjusted; the number and shape of the connecting portions 312 can also be changed and adjusted. The connecting portion 312 can be a straight strip or an arcuate strip. The number of connecting portions 312 can be appropriately adjusted, as long as the AC signal connected by the wiring portion 313 can be transmitted to each electrode unit 311. A relatively simple method is that the electrode units 311 in each row are connected to each other through the connecting portion 312 and the rows are also connected through the connecting portion 312. The number of electrode units 311 covered by each adhesive member 33 is also adjustable. There can be only one adhesive member 33 covering all electrode units 311, or a separate adhesive member 33 can be provided for each electrode unit 311. These structures of the electrode array 31 and the adhesive member 33 do not constitute a limitation to the present application.

[0046] refer to Figure 6As shown, the difference between the electrode patch 30' in the second embodiment of the present application and the electrode patch 30 in the first embodiment is the number and arrangement of the electrode units provided therein. The electrode array 31' of the electrode patch 30' is provided with thirteen electrode units 311', and the electrode units 311' are also surrounded by support members 32'. The electrode units 311' are arranged in five rows and five columns, with two electrode units 311' in each of the first and last rows, and three electrode units 311' in each of the three middle rows. The electrode units 311' in the first and last rows are staggered with the electrode units 311' in the three middle rows, and each electrode unit 311' is connected to at least two electrode units 311' around it via a corresponding connecting portion 312'. The electrode array 31' is provided with five adhesive members 33', and each adhesive member 33' covers a row of electrode units 311'. In other embodiments, each electrode unit 311' may also be connected to at least one adjacent electrode unit 311' via a corresponding connecting portion 312', and adjacent electrode units 311' in each electrode unit 311' located on the periphery of the electrode array 31' are disconnected from each other. The hierarchical structure of the electrode units 311' is the same as that of the electrode units 311 in the first embodiment.

[0047] refer to Figure 7 As shown, the difference between the electrode patch 30" in the third embodiment of the present application and the electrode patch 30 in the first embodiment is the number and arrangement of the electrode units provided therein. The electrode array 31" of the electrode patch 30" is provided with twenty electrode units 311", arranged in six rows and four columns, and each electrode unit 311" is also surrounded by a support member 32". The first and last rows are each provided with two electrode units 311", and the middle four rows are each provided with four electrode units 311". The two electrode units 311" in the first and last rows are respectively located on the two middle columns, and each electrode unit 311" is connected to at least three electrode units 311" around it through a corresponding connecting portion 312". The electrode array 31" is provided with ten adhesive members 33", and each adhesive member 33" covers two adjacent electrode units 311" in the same row. In other embodiments, each electrode unit 311" may also be connected to at least one adjacent electrode unit 311" via a corresponding connecting portion 312", and adjacent electrode units 311" in each electrode unit 311" located at the periphery of the electrode array 31" are disconnected. There may be multiple adhesive members 34" and they are respectively arranged in a one-to-one correspondence with the electrode units 311". The hierarchical structure of the electrode units 311" is the same as that of the electrode units 311 in the first embodiment.

[0048] refer to Figure 8As shown, the electrode patch 40 in the fourth embodiment of the present application includes a plurality of electrode arrays 41 and a paste member 42. The electrode array 41 is in the shape of a "king character", including nine electrode units 411 arranged in a matrix, a plurality of connecting portions 412 connecting two adjacent electrode units 411, and a wiring portion 413. The overall shape of the electrode array 41 is the same as that of the electrode array 31 of the electrode patch 30 in the first embodiment. The main difference between it and the electrode array 31 is the hierarchical structure of its electrode unit 411.

[0049] Refer to Figures 9 and 10 As shown, the electrode unit 411 includes a main body portion (not labeled). The main body portion (not labeled) includes a substrate 4111 made of polyimide or polyester film and a conductive sheet 4112 provided on the upper surface of the substrate 4111. The electrode unit 411 further includes an insulating layer 4113 covering the substrate 4111 and partially covering the conductive sheet 4112, a dielectric layer 4114 covering the insulating layer 4113 and the part of the conductive sheet 4112 exposed from the insulating layer 4113, and an alloy layer 4115 covering the dielectric layer 4114. The connecting portion 412, the wiring portion 413, and the main body portion (not labeled) of the electrode unit 411 together constitute a flexible printed circuit board (not labeled) of the electrode array 41. A through hole 4116 is provided at the center position of the conductive sheet 4112. Some electrode units 411 further include a pair of pads 4117 provided on the substrate 4111 and located in the through hole 4116 for electrically connecting the temperature detection unit 4118.

[0050] Figure 10 The shaded part in shows the insulating layer 4113. The insulating layer 4113 presses the conductive sheet 4112 on the substrate 4111 and exposes part of the conductive sheet 4112. The insulating layer 4113 is generally arranged in a hub shape. Four fan-shaped regions 4119 of the conductive sheet 4112 are exposed from the insulating layer 4113, and the pads 4117 are also exposed from the insulating layer 4113. The insulating layer 4113 covers part of the conductive sheet 4112 to block the transmission of electrical signals from the part of the conductive sheet 4112 covered by the insulating layer 4113 to the dielectric layer 4114, thereby reducing the heating area of the electrode unit 411 and improving the heat dissipation effect of the electrode unit 411. The insulating layer 4113 can extend to each connecting portion 412 and wiring portion 413.

[0051] The dielectric layer 4114 is applied to each electrode unit 411. It completely covers the top surface of the conductive sheet 4112 to prevent direct contact between the conductive sheet 4112 and the patient, thereby preventing non-capacitive coupling between the electrode units 411 and the patient, which could compromise patient safety. The dielectric layer 4114 is a polymer dielectric layer with a high dielectric constant and low dielectric loss. It is made from a thin film material with a non-fixed crystal orientation, high flexibility, and high toughness. The dielectric layer 4114 is made of a polymer with a dielectric constant of at least 20 and a dielectric strength of at least 40 V / μm to prevent breakdown under normal applied voltage. The polymer exhibits relaxor ferroelectric behavior and can be a vinylidene fluoride-based polymer, such as P(VDF-TrFE-CTFE), P(VDF-TrFE-CFE), or P(VDF-TrFE-CFE-CTFE); or a polyamide composite, such as piperazine-biuret copolymer. The dielectric layer 4114 can be formed on the surface of the conductive sheet 4112 by evaporation, sputtering, or ion plating vapor deposition, or by printing, spraying, or casting. The thickness of the dielectric layer 4114 is 3 μm-10 μm.

[0052] Alloy layer 4115, disposed on dielectric layer 4114, serves as an auxiliary layer to enhance electrical conductivity between dielectric layer 4114 and adhesive member 33. Alloy layer 4115 is slightly smaller than dielectric layer 4114, meaning its edge is positioned inward of the edge of dielectric layer 4114. Alloy layer 4115 can be made of one or more of a zinc-aluminum alloy, a zinc-copper alloy, silver-titanium, or graphite. Alloy layer 4115 can be deposited on the surface of dielectric layer 4114 using vapor deposition.

[0053] refer to Figure 11 As shown, temperature detection unit 4118 includes temperature sensor 4118A. Temperature sensor 4118A has a signal terminal (not shown) and a ground terminal (not shown), each of which is soldered to a corresponding pad 4117 or electrically connected to the corresponding pad 4117 via a lead 4118B. Temperature detection unit 4118 also includes sealant 4118C, which is filled into through-hole 4116 after temperature sensor 4118A is soldered to substrate 4111 to seal temperature sensor 4118A. This prevents moisture from corroding temperature sensor 4118A and causing failure of temperature sensor 4118A. Dielectric layer 4114 and alloy layer 4115 cover sealant 4118C.

[0054] refer to Figure 12As shown, the electrode units 411' of the electrode array 41' of the electrode patch in the fifth embodiment of the present application have the same hierarchical structure as the electrode units 411 of the electrode array 41 of the electrode patch 40, and the only difference between the two is the number and arrangement of the electrode units. The electrode array 41' is provided with twenty electrode units 411', which are roughly arranged in four rows and six columns, wherein the first and second rows are arranged in an arc segment that is concave in the middle and upturned at both ends, and the third and fourth rows are arranged in an arc segment that is convex in the middle and depressed at both ends.

[0055] Figure 13 An electrode patch 50 in a sixth embodiment of the present application is provided. The electrode array 51 of the electrode patch 50 in this embodiment has the same hierarchical structure as the electrode array 41 of the electrode patch 40. The difference between the two is that the shape of the electrode array is different and the shape, number and arrangement of the electrode unit 511 are also different. However, the hierarchical structure of a single electrode unit 511 is the same as the layered structure of the electrode unit 411 of the electrode patch 40. The following mainly explains the differences.

[0056] The outer contour of the electrode array 51 is roughly teardrop-shaped, with the portion of its outer contour covered by the adhesive 52 shown in dashed lines. The electrode array 51 includes six electrode units 511 spaced apart, a plurality of connecting portions 512 connecting two adjacent electrode units 511, and a wiring portion 513 extending outward from one of the connecting portions 512. The six electrode units 511 are divided into a left portion and a right portion spaced apart and symmetrically arranged in the shape of half a teardrop. The left portion includes a first electrode unit 511A, a second electrode unit 511B, and a third electrode unit 511C spaced apart from each other from top to bottom, and the right portion includes a fourth electrode unit 511D, a fifth electrode unit 511E, and a sixth electrode unit 511F spaced apart from each other from top to bottom.

[0057] Each electrode unit 511 is arranged in a sheet-like shape. The first electrode unit 511A and the fourth electrode unit 511D are arranged roughly in a triangular shape, the second electrode unit 511B and the fifth electrode unit 511E are arranged roughly in a trapezoidal shape, and the third electrode unit 511C and the sixth electrode unit 511F are arranged roughly in a fan shape. The electrode array 51 uses electrode units 511 of different areas to better adapt to the attachment requirements of different locations on the patient's body surface, especially for tumor electric field therapy in areas such as the head with small attachment areas and few flat areas. Specifically, the first electrode unit 511A, the third electrode unit 511C, the fourth electrode unit 511D, and the sixth electrode unit 511F are each equipped with a temperature detection unit (not shown).

[0058] The plurality of connecting portions 512 include a first connecting portion 5121 and a plurality of second connecting portions 5122. The first connecting portion 5121 connects the second electrode unit 511B and the fifth electrode unit 511E to achieve electrical connection between the left and right parts of the electrode array 51. The first connecting portion 5121 is located in the gap (unnumbered) formed between the left and right parts of the electrode array 51. The plurality of second connecting portions 5122 respectively connect between two adjacent electrode units 511 in the left part and between two adjacent electrode units 511 in the right part. The second connecting portion 5122 is arranged in an S-shape, and the relative position of the two electrode units 511 it connects can be appropriately adjusted to facilitate application. The wiring portion 513 extends downward from the first connecting portion 5121 along the gap between the left and right parts.

[0059] The adhesive members 52 are provided corresponding to the electrode units 511, and there are a total of 6 pieces. Their shapes are consistent with the outer contours of the corresponding electrode units 511. The adhesive members 52 cover the electrode units 511 in the same manner as the adhesive members 33 cover the electrode units 311 in the first embodiment of the present application described above. The adhesive members 52 cover the corresponding electrode units 511 in a one-to-one correspondence. In other embodiments, each electrode unit 511 is provided with a temperature detection unit (not shown), and the adhesive member 52 is provided with a groove (not shown) corresponding to the temperature detection unit (not shown), which can improve the comfort of the patient when applying the electrode patch 50 and ensure that the electrode units 511 and the electrode patch 50 have stable electrical performance. The adhesive member 52 can also be a whole piece, covering the electrode array 51 as a whole.

[0060] The above is only a preferred embodiment of the present application and is not intended to limit the present application. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present application should be included in the scope of protection of the present application.

Claims

1. An electrode patch comprising an electrode array and one or more adhesive members, wherein the electrode array comprises a plurality of electrode units, a plurality of connecting portions connecting two adjacent electrode units, and a wiring portion, characterized in that: The adhesive member includes a first layer covering the electrode array and a second layer for being applied to the patient's body surface, and the viscosity of the first layer is greater than that of the second layer.

2. The electrode patch according to claim 1, characterized in that: The electrode array has a side surface away from the adhesive member and exposed to the outside during use.

3. The electrode patch according to claim 1, characterized in that: The first layer and the second layer are composed of the same components, which include at least one component that affects viscosity. The content ratio of the at least one component that affects viscosity in the first layer is greater than that in the second layer.

4. The electrode patch according to claim 1, characterized in that: The first layer and the second layer have different compositions.

5. The electrode patch according to claim 1, characterized in that: The adhesive member includes polyacrylic acid.

6. The electrode patch according to claim 1, characterized in that: The adhesive includes magnesium hydroxide.

7. The electrode patch according to claim 1, characterized in that: The electrode unit includes a substrate, a conductive sheet, an insulating layer and a dielectric layer. The insulating layer presses the conductive sheet onto the substrate. The dielectric layer is laid on the insulating layer and the area where the conductive sheet is exposed from the insulating layer.

8. The electrode patch according to claim 7, characterized in that: The electrode unit further includes an alloy layer, the alloy layer covers the dielectric layer, and the adhesive member covers the alloy layer.

9. The electrode patch according to claim 1, characterized in that: The plurality of adhesive members cover the electrode units in a one-to-one correspondence.

10. A tumor electric field treatment device, characterized in that: The device comprises an electric field generator, an adapter and a plurality of electrode patches arranged in pairs as claimed in any one of claims 1 to 9.

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