Temperature-controllable biological material 3D printing platform convenient to level

Abstract

The utility model relates to a temperature-controllable biological material 3D printing platform convenient to level. Comprising a printing substrate, fixing clamping pieces, a printing bed and a heat conducting plate. A square mounting hole is formed in the middle of the printing substrate, a base corresponding to the mounting hole in position is arranged at the bottom of the printing substrate, then a groove is formed in the middle of the printing substrate, and a printing bed, a heat conduction plate, a temperature measuring piece, a heating film, a refrigeration piece, a heat dissipation plate, a base and a heat dissipation module are sequentially arranged in the groove from top to bottom. A countersunk bolt hole is formed in the heat conduction plate, a leveling spring is arranged between the heat dissipation plate and the base, and a leveling screw sequentially penetrates through the countersunk bolt hole, the heat dissipation plate and the leveling spring from top to bottom and then is in threaded connection with the base. Through the heating film and the refrigeration sheet, the printing platform has two temperature control modes, the printing platform can be suitable for different biological materials, the applicability is wider, and the use requirement of workers is met.

Description

Technical Field

[0001] The present application relates to the technical field of 3D biomaterial printing equipment, and in particular to a temperature-controllable biomaterial 3D printing platform that is easy to level. Background Art

[0002] 3D biomaterial printing refers to the use of computers to precisely control the layer-by-layer deposition of "bio-ink" composed of biomaterials or cells, supported by modern medical precision scanning and computer rapid modeling technology, to prepare implants with biomimetic structures. Currently, many biomaterials are used to prepare living tissues through 3D bioprinting to replace dysfunctional or damaged organs, effectively saving patients' lives.

[0003] Currently, existing 3D biomaterial printing platforms generally only have one temperature control mode, namely heating mode or cooling mode. However, in actual use, different biomaterials require different temperatures, and existing bioprinting platforms cannot meet actual usage needs. Summary of the Invention

[0004] In order to solve or partially solve the problems existing in the related art, the present application provides a temperature-controllable biomaterial 3D printing platform that is easy to level, aiming to solve the technical problem of the single temperature control mode in the existing technology.

[0005] To this end, the present application provides a temperature-controllable biomaterial 3D printing platform that is conveniently leveled, including a printing substrate, a fixing clip, a printing bed, and a heat conducting plate;

[0006] A square mounting hole is provided in the middle of the printed base plate, a base corresponding to the position of the mounting hole is provided at the bottom of the printed base plate, and a groove is formed in the middle of the printed base plate. A printing bed, a heat conducting plate, a temperature measuring plate, a heating film, a cooling plate, and a heat dissipation plate are provided in the groove from top to bottom. A countersunk bolt hole is provided on the heat conducting plate, and a leveling spring is provided between the heat dissipation plate and the base. A leveling screw passes through the countersunk bolt hole, the heat dissipation plate, and the leveling spring in order from top to bottom, and is then screwed to the base. A heat dissipation module is provided at the bottom of the heat dissipation plate.

[0007] One end of the fixing clip is fixed to the surface of the printing base plate 1 by a pressure plate screw and a spring, and the other end extends above the printing bed.

[0008] In some embodiments, a control system is further included, and the temperature measuring plate, heating film, cooling plate and heat dissipation module are electrically connected to the control system respectively.

[0009] In some embodiments, a display screen is further included, and the display screen is electrically connected to the control system.

[0010] In some embodiments, the temperature measuring piece is a thin film type patch type thermocouple.

[0011] In some embodiments, the heating film has a thickness of less than 0.25 mm and is in close contact with the heat conducting plate via a heat transfer resin. The heating film and the heat conducting plate are of equal size.

[0012] In some embodiments, the cooling plate is a plate-like structure, one side of which is a cooling surface and the other side is a heating surface, and the cooling surface is in close contact with the heating film 7 through a heat transfer resin.

[0013] In some embodiments, the heat sink is made of a copper plate, and the heat sink is in close contact with the hot surface of the refrigeration fin via a heat transfer resin.

[0014] In some embodiments, the heat dissipation module includes a water cooling pipe, a water pump, a fan and a remote heat dissipation fan, and the water cooling pipe is connected to the water pump through a pipeline.

[0015] The technical solution provided by this application may have the following beneficial effects:

[0016] This application uses a heating film and a cooling sheet to enable the printing platform to have two temperature control modes, so that the printing platform can be used with different biological materials, with a wider applicability to meet the needs of staff.

[0017] It should be understood that the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The above and other objects, features and advantages of the present application will become more apparent through a more detailed description of exemplary embodiments of the present application in conjunction with the accompanying drawings, wherein the same reference numerals generally represent the same components in the exemplary embodiments of the present application.

[0019] Figure 1 Schematic diagram of the structure of the printing platform shown in the embodiment of the present application;

[0020] Figure 2 is a control block diagram of a printing platform shown in an embodiment of the present application;

[0021] Reference numerals:

[0022] 1. Print base plate; 2. Pressure plate screws and springs; 3. Fixing clips; 4. Print bed; 5. Temperature measuring plate; 6. Heat conducting plate; 7. Heating film; 8. Refrigeration plate; 9. Heat sink; 10. Leveling screws; 11. Leveling springs; 12. Heat sink module; 13. Base. DETAILED DESCRIPTION

[0023] The following describes embodiments of the present application in more detail with reference to the accompanying drawings. Although the accompanying drawings illustrate embodiments of the present application, it should be understood that the present application can be implemented in various forms and should not be limited by the embodiments described herein. Rather, these embodiments are provided to make the present application more thorough and complete, and to fully convey the scope of the present application to those skilled in the art.

[0024] It should be understood that although the terms "first", "second", "third", etc. may be used in this application to describe various information, this information should not be limited to these terms. These terms are only used to distinguish information of the same type from each other. For example, without departing from the scope of this application, the first information may also be referred to as the second information, and similarly, the second information may also be referred to as the first information. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the features. In the description of this application, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0025] In the description of this application, it should be understood that the terms "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the accompanying drawings, and are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on this application.

[0026] Unless otherwise expressly specified or limited, terms such as "mounted," "connected," "connect," and "fixed" should be interpreted broadly. For example, they may refer to fixed or detachable connections, or integration; mechanical or electrical connections; direct or indirect connections through an intermediary; and internal communication between two components or interaction between two components. Those skilled in the art will understand the specific meanings of these terms in this application based on the specific circumstances.

[0027] Example 1

[0028] like Figure 1 and 2 As shown, the present application provides a temperature-controllable biomaterial 3D printing platform that is convenient to level, including a printing base plate 1, a fixing clip 3, a printing bed 4 and a heat conducting plate 6;

[0029] A square mounting hole is provided in the center of the printed base plate 1. A base 13 is located at the bottom of the printed base plate 1, corresponding to the mounting hole. This recess forms a central recess within the printed base plate 1. Within this recess, from top to bottom, are located the print bed 4, heat conducting plate 6, temperature measuring plate 5, heating film 7, cooling plate 8, and heat sink 9. Countersunk bolt holes are provided in the heat conducting plate 6. A leveling spring 11 is positioned between the heat sink 9 and the base 13. Leveling screws 10 pass through the countersunk bolt holes, heat sink 9, and leveling spring 11, threading into the base 13. This clamps the temperature measuring plate 5, heating film 7, and cooling plate 8 between the heat conducting plate 6 and the heat sink 9. Four leveling screws 10 are located at the four corners of the heat conducting plate 6. A heat sink module 12 is located at the bottom of the heat sink 9.

[0030] During use, the compression of the leveling spring 11 can be adjusted by tightening or loosening the leveling screw 10, thereby adjusting the level of the heat conducting plate 6, that is, adjusting the level of the print bed 4 on the heat conducting plate 6, which is easy to adjust. At the same time, heating can be achieved through the heating film 7 and cooling can be achieved through the cooling plate 8, that is, it has both cooling and heating temperature control modes, effectively improving the applicability of the printing platform.

[0031] One end of the fixing clip 3 is fixed to the surface of the printing substrate 1 by a pressure plate screw and a spring 2, and the other end extends to the top of the printing bed 4. When the pressure plate screw is tightened, the fixing clip 3 presses the printing bed 4 to ensure that the printing bed 4 does not move during the printing process, thereby improving the printing accuracy. When the printing is completed, if the printed product needs to be moved, the printing bed 4 can be directly removed from the fixing clip for moving operation, which is convenient for movement.

[0032] It should be noted that the print bed 4 includes but is not limited to a print platform and a culture dish, the print substrate 1 is the supporting plate of the print bed 4, the heat conducting plate 6 is in direct contact with the print bed 4, and the heat conducting plate 6 is made of a metal material with good heat and cold conductivity.

[0033] Based on the above disclosure, the heat conducting plate 6 is arranged under the printing bed 4. Since the heat conducting plate 6 is in direct contact with the printing bed 4, it can better transfer heat or cold to the printing bed 4. In the case of two temperature control modes in this application, when printing, the control system can select the heating mode or the cooling mode according to the difference between the user-set temperature and the temperature measured by the temperature measuring piece 5, and adjust the temperature during the printing process in real time.

[0034] In a feasible embodiment, the temperature-controllable biomaterial 3D printing platform further includes a control system, and the temperature measuring plate 5, the heating film 7, the cooling plate 8 and the heat dissipation module 12 are electrically connected to the control system respectively.

[0035] Based on the above disclosed content, the control system is electrically connected to the temperature measuring film 5, the heating film 7, the cooling film 8, the heat sink 9 and the heat dissipation module 12. In the heating mode, the heating film 7 is controlled to work, and the cooling film 8 and the heat dissipation module 12 stop working; in the cooling mode, the cooling film 8 and the heat dissipation module 12 are controlled to work, and the heating film 7 stops working.

[0036] In a feasible embodiment, it further includes a display screen, which is electrically connected to the control system.

[0037] It should be noted that the user can set the temperature through the display screen, and the display screen transmits the temperature set by the user to the control system.

[0038] In a feasible embodiment, the temperature measuring piece 5 is a thin film type patch type thermocouple.

[0039] Based on the above disclosure, the heat conducting plate 6 is in direct contact with the temperature measuring piece 5, and the temperature measuring piece 5 accurately measures the real-time temperature and transmits the real-time temperature data to the control system. The control system compares the real-time temperature data with the temperature value set by the user, and determines whether to perform heating mode or cooling mode, thereby achieving precise temperature control.

[0040] In a feasible embodiment, the heating film 7 is less than 0.25 mm thick and is tightly attached to the heat conducting plate 6 via a heat transfer resin. The heating film 7 and the heat conducting plate 6 are equal in size.

[0041] Specifically, preferably, the heating film 7 adopts a high-power resistance heating film to control the heating power and heat up quickly. The size of the heating film 7 is approximately equal to the heat conducting plate 6, ensuring that the heat conducting plate 6 is heated evenly during the heating process. The heating film 7 can be used not only to transfer heat, but also to transfer cold.

[0042] Based on the above disclosure, the heating film 7 is in direct contact with the heat conducting plate 6. At the same time, the size of the heating film 7 is approximately equal to that of the heat conducting plate 6, which can better transfer heat to the print bed 4 through the heat conducting plate 6 to ensure its temperature requirements during the printing process. In the cooling mode, the heating film 7 stops heating and acts as a cold transfer. The conductor transfers the cold energy generated by the cooling plate 8 to the print bed 4 through the heat conducting plate 6. When the temperature measured by the temperature measuring plate 5 is equal to the temperature value set by the user, the heating film 7 stops working.

[0043] In a feasible embodiment, the cooling plate 8 is a plate-like structure, one side of which is a cooling surface and the other side is a heating surface. The cooling surface is tightly attached to the heating film 7 through a heat transfer resin.

[0044] Specifically, preferably, the cooling plate 8 adopts a semiconductor cooling plate to control the cooling power. In the cooling mode, the cooling surface generates low temperature and heat is generated on the hot surface. The heat is discharged through the heat dissipation plate 9 and the heat dissipation module 12. The cooling surface and the heating film 7 are directly connected through the heat transfer resin, wherein the heat transfer resin is a material with good heat and cold transfer properties.

[0045] Based on the above disclosure, in the cooling mode, the cooling surface generates cold energy, which is transferred to the print bed 4 through the heating film 7 and the heat conducting plate 6. The hot surface extracts the heat from the heating film 7 and the heat conducting plate 6 and transfers it to the heat dissipation plate 9 and the heat dissipation module 12 for cooling. When the temperature measured by the temperature measuring plate 5 is equal to the temperature value set by the user, the cooling plate 8 stops working.

[0046] In a feasible embodiment, the heat sink 9 is made of a copper plate, and the heat sink 9 is closely attached to the hot surface of the refrigeration fin via a heat transfer resin.

[0047] Based on the above disclosure, the hot surface of the cooling plate 8 conducts heat from the print bed 4, the heat conducting plate 6 and the heating film 7, and transfers the heat to the heat sink 9. Since the heat sink 9 is made of copper plate, the heat can be quickly transferred to the heat sink 9, and then transferred to the heat dissipation module 12.

[0048] In one feasible embodiment, the heat dissipation module 12 is disposed below the heat sink 9 and includes a water-cooling pipe, a water pump, a fan, and a distal heat dissipation fan. The water-cooling pipe and the water pump are connected by a pipe. The water-cooling pipe passes through the heat sink 9 to remove heat from the heat sink 9. The fan blows toward the heat sink 9, dissipating heat from the heat sink 9 through air cooling. Simultaneously, the water-cooling pipe extends in front of the distal heat dissipation fan, also cooling the water-cooling pipe through air cooling.

[0049] It should be noted that in the cooling mode, the heat dissipation module 12 works, and the heat generated by the hot surface of the refrigeration plate 8 is transferred to the heat sink. At this time, the water cooling pipe, water pump and fan work, and the heat is taken away by the water flow. At the same time, the heat is transferred to the air through the fan at the far end to achieve uninterrupted heat dissipation.

[0050] In a feasible embodiment, the heat conducting plate 6 and the heat dissipating plate 9 are fixed to the base 13 by leveling screws 10 and leveling springs 11 .

[0051] Example 2

[0052] like Figure 2As shown, the present application provides a temperature-controllable biomaterial 3D printing platform that is easy to level. In a feasible implementation scheme, the user sets the temperature during the printing process through the display screen, and transmits the set temperature to the control system. The temperature measuring piece 5 measures the temperature of the heat conducting plate 6 and transmits the measured temperature to the control system. The control system compares the temperature measured by the temperature measuring piece 5 with the temperature set by the user. If the measured temperature is lower than the set temperature, the heating mode is turned on, and the control system controls the heating film 7 to generate heat, and then transfers the heat to the heat conducting plate 6. Since the heat conducting plate 6 is in direct contact with the printing bed 4, the printing bed 4 can obtain better heat transfer and reduce heat loss. In this state, the refrigeration plate 8 and the heat dissipation module 12 stop working to avoid invalid loss of heat generated by the heating film 7.

[0053] When the measured temperature is higher than the set temperature, the cooling mode is turned on, the control system controls the cooling plate 8 to work, the cooling surface generates cold energy, and the cold energy is transferred to the heat conducting plate 6 through the heating film 7. Since the heating film 7 and the cooling plate 8 are bonded together by the heat transfer resin, the cold energy can be better transferred. At the same time, heat is generated from the hot surface of the cooling plate 8 and is exported through the heat dissipation plate 9 and the heat dissipation module 12. The heat dissipation module 12 is a closed water cooling system. The heat is transferred to the air through the water pump, water cooling pipe and fan in the heat dissipation module 12, as well as the fan at the far end, to lower the water temperature, thereby achieving uninterrupted heat dissipation. In this state, the heating film 7 stops working.

[0054] When the control system determines that the temperature measured by the temperature measuring plate 5 is equal to the temperature set by the user, the heating film 7, the cooling plate 8 and the heat dissipation module 12 all stop working. When the control system determines that the error between the measured temperature and the user set temperature exceeds 1°C, the corresponding cooling or heating mode is turned on based on the comparison between the two. This application can control the temperature within a smaller temperature difference range, reduce the number of starts and stops of the heating film 7 and the cooling plate 8, extend the life of the equipment, and reduce the power consumption of the equipment.

[0055] Beneficial effects of this application:

[0056] 1) The print bed is clamped by a fixed clip to ensure that the print bed does not move during printing, thereby improving printing accuracy. Since the finished biomaterial is printed directly on the print bed, it does not need to directly contact the table. At the same time, the entire printing process is performed in a sterile environment, reducing the possibility of biomaterial contamination. When the printed product needs to be moved after printing, the print bed can be directly removed from the fixed clip for moving, making it easy to move.

[0057] 2) This application is equipped with a temperature measuring piece, a heating film, a cooling piece, a heat sink and a heat dissipation module, which can be turned on for heating and cooling at the same time to obtain a wider temperature control range, provide the ambient temperature required by more biological materials, and expand the types of biological materials that can be used for printing. The user can also set the temperature by himself through the display screen. During the printing process, the control system can turn on the heating or cooling mode according to the temperature set by the user, and control the temperature within a certain range of the set temperature to ensure the temperature stability during the printing process. At the same time, the heat conduction plate is in direct contact with the print bed, which can better transfer heat and cold.

[0058] 3) The heat conduction plate is fixed to the print bed via four sets of leveling screws and leveling springs. During leveling, the print bed's horizontality can be controlled by adjusting some or all of the leveling screws, improving the leveling accuracy and achieving leveling of the print bed.

[0059] The embodiments of the present application have been described above. The above description is illustrative and not exhaustive, and is not limited to the disclosed embodiments. Many modifications and variations will be apparent to those skilled in the art without departing from the scope and spirit of the described embodiments. The terminology used herein is selected to best explain the principles of the embodiments, their practical applications, or improvements to the technology in the market, or to enable other persons skilled in the art to understand the embodiments disclosed herein.

Claims

1. A temperature-controlled biomaterial 3D printing platform with convenient leveling, characterized by: It comprises a printing base plate (1), a fixing clip (3), a printing bed (4) and a heat conducting plate (6); A square mounting hole is provided in the middle of the printing substrate (1), and a base (13) corresponding to the position of the mounting hole is provided at the bottom of the printing substrate (1), and a groove is formed in the middle of the printing substrate (1), and a printing bed (4), a heat conducting plate (6), a temperature measuring plate (5), a heating film (7), a cooling plate (8), and a heat dissipation plate (9) are provided in the groove from top to bottom. A countersunk bolt hole is provided on the heat conducting plate (6), and a leveling spring (11) is provided between the heat dissipation plate (9) and the base (13). A leveling screw (10) passes through the countersunk bolt hole, the heat dissipation plate (9), and the leveling spring (11) from top to bottom and is screwed to the base (13). A heat dissipation module (12) is provided at the bottom of the heat dissipation plate (9). One end of the fixing clip (3) is fixed to the surface of the printing base plate (1) via a pressure plate screw and a spring (2), and the other end extends above the printing bed (4).

2. The conveniently leveled temperature-controllable biomaterial 3D printing platform according to claim 1, characterized in that: It also includes a control system, and the temperature measuring plate (5), the heating film (7), the cooling plate (8) and the heat dissipation module (12) are respectively electrically connected to the control system.

3. The conveniently leveled temperature-controllable biomaterial 3D printing platform according to claim 2, characterized in that: It also includes a display screen, which is electrically connected to the control system.

4. The conveniently leveled temperature-controllable biomaterial 3D printing platform according to claim 1, characterized in that: The temperature measuring piece (5) is a thin film type patch type thermocouple.

5. The temperature-controllable biomaterial 3D printing platform with convenient leveling according to claim 1, characterized in that: The thickness of the heating film (7) is less than 0.25 mm, and it is in close contact with the heat conducting plate (6) through heat transfer resin. The heating film (7) and the heat conducting plate (6) are of equal size.

6. The conveniently leveled temperature-controllable biomaterial 3D printing platform according to claim 1, characterized in that: The cooling plate (8) is a plate-like structure, one side of which is a cooling surface and the other side is a heating surface, and the cooling surface is in close contact with the heating film (7) via a heat transfer resin.

7. The conveniently leveled temperature-controllable biomaterial 3D printing platform according to claim 6, characterized in that: The heat dissipation plate (9) is made of a copper plate, and the heat dissipation plate (9) is in close contact with the hot surface of the refrigeration plate through a heat transfer resin.

8. The temperature-controllable biomaterial 3D printing platform with convenient leveling according to claim 1, characterized in that: The heat dissipation module (12) comprises a water cooling pipe, a water pump, a fan and a remote heat dissipation fan, and the water cooling pipe is connected to the water pump via a pipeline.

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