Percolation device for biological medicine manufacturing

Abstract

The utility model relates to the field of biological medicine manufacturing, in particular to a percolation device for biological medicine manufacturing. The technical problems that raw material residues are inconvenient to fish, the dissolving speed of effective components is low, and the percolation efficiency is low in a traditional method are solved. A percolation device for biological medicine manufacturing comprises a bottom frame, a mounting frame is fixedly connected to the upper portion of the bottom frame, a barrel is fixedly connected to the mounting frame, two magnets are fixedly connected to the bottom of the barrel, and a rotating shaft is rotationally connected to the bottom frame. The connecting rod continues to move downwards to be in contact with the filter screen, the filter screen is pushed downwards, the filter screen moves downwards to be separated from the magnet, the magnet does not attract the filter screen any more, under the action of gravity, the filter screen can fall onto the limiting plate, and the filter screen continues to move downwards to bring motherwort raw material residues out of the barrel, so that the raw material residues are conveniently discharged.

Description

Technical Field

[0001] The utility model relates to the field of biopharmaceutical manufacturing, in particular to a percolation device for biopharmaceutical manufacturing. Background Art

[0002] Motherwort is a herbaceous plant widely distributed throughout my country and used as medicine, making it a common traditional Chinese medicine. The active ingredient in motherwort is leonurine (also known as leonurine), which has the effects of promoting blood circulation, removing blood stasis, promoting diuresis, and reducing swelling. It is a good remedy for gynecological diseases in ancient medicine.

[0003] Currently, percolation is an effective method for extracting motherwort. This method requires crushing the motherwort plant, then continuously spraying the crushed motherwort material with an extracting solution (such as ethanol or acetic acid). The extracting solution passes through the crushed motherwort material from top to bottom, extracting the motherwort. Traditional methods require salvaging the crushed motherwort material from the reactor after percolation. Due to the small size of the crushed motherwort material, salvaging is not convenient, and the effective ingredient dissolves slowly during percolation, resulting in low percolation efficiency. Utility Model Content

[0004] In order to overcome the shortcomings of traditional methods such as the inconvenience of salvaging raw material residues, slow dissolution of active ingredients and low percolation efficiency, the utility model provides a percolation device for biopharmaceutical manufacturing that can easily discharge raw material residues, accelerate the dissolution rate of active ingredients and improve percolation efficiency.

[0005] A percolation device for biopharmaceutical manufacturing comprises a base frame, a mounting frame fixedly connected to the upper portion of the base frame, a barrel fixedly connected to the mounting frame, two magnets fixedly connected to the bottom of the barrel, the two magnets being symmetrically arranged, a rotating shaft rotatably connected to the base frame, the upper end of the rotating shaft being located within the barrel, a filter screen slidably connected to the shaft, the top of the filter screen in contact with the bottom of the barrel, and the filter screen being made of an iron material. The magnets attract the filter screen, a spray frame fixedly connected to the upper portion of the barrel, and a discharge assembly provided on the base frame, which can carry the residual raw material after percolation out of the barrel, thereby facilitating the discharge of the residual raw material after percolation.

[0006] Further explanation: the discharge assembly includes a guide rail, the guide rail is fixedly connected to the side wall of the base frame, an electric slider is slidably connected to the guide rail, two connecting rods are fixedly connected to the electric slider, the two connecting rods are symmetrically arranged, both of the connecting rods pass through the filter, both of the connecting rods are fixedly connected to a limiting plate, the tops of the two limiting plates are in contact with the bottom of the filter, a pressure plate is fixedly connected between the two connecting rods, and the pressure plate is sleeved on the rotating shaft.

[0007] Further description, it also includes a motor, the motor is provided on the upper part of the base frame, a transmission assembly is connected between the motor and the rotating shaft, the upper end of the rotating shaft is fixedly connected to a rotating frame, a plurality of protrusions are provided on the rotating frame, and the plurality of protrusions on the rotating frame are evenly spaced, four sliding blocks are slidably connected to the cylinder, the four sliding blocks are evenly spaced, two return springs are provided between each sliding block and the cylinder, and the two return springs on the same sliding block are symmetrically arranged, and each sliding block is fixed with a contact shaft, and each contact shaft will contact the protrusions on the rotating frame.

[0008] To further illustrate, the transmission assembly includes a driving wheel, a driven wheel and a transmission belt. The driving wheel is fixedly connected to the output shaft of the motor, the driven wheel is fixedly connected to the upper end of the rotating shaft, and a transmission belt is wound between the driving wheel and the driven wheel.

[0009] Further description is made, and there are also protrusions. A plurality of the protrusions are fixedly connected to the upper part of the rotating shaft, and the plurality of the protrusions are evenly spaced.

[0010] The beneficial effects of the utility model are as follows: 1. The staff starts the electric slider to move downward, driving the connecting rod to move downward, the connecting rod pressure plate and the limit plate move downward, the limit plate is out of contact with the filter screen, the pressure plate will enter the cylinder and squeeze the motherwort raw material residue, squeeze out the extractant with effective ingredients extracted from the motherwort raw material residue, and reduce the waste of effective ingredients.

[0011] 2. Continue to move downward through the connecting rod to contact the filter and push the filter downward. The filter moves downward and disengages from the magnet. The magnet no longer adsorbs the filter. Under the action of gravity, the filter will fall down to the limit plate. The filter continues to move downward and will bring the motherwort raw material residue out of the cylinder, making it easier to discharge the raw material residue.

[0012] 3. The staff starts the motor to drive the rotating shaft to rotate, and the rotating shaft drives the rotating frame to rotate. Several protrusions on the rotating frame will contact the contact shaft in turn and squeeze the contact shaft toward the rotating shaft. The movement of the contact shaft toward the rotating shaft drives the sliding block to move toward the rotating shaft. The sliding block will squeeze the motherwort raw material in the cylinder, accelerate the dissolution rate of the effective ingredients, and improve the percolation efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 This is a schematic diagram of the first three-dimensional structure of the utility model.

[0014] Figure 2 This is a schematic diagram of the second three-dimensional structure of the present invention.

[0015] Figure 3It is a partial three-dimensional structural diagram of the utility model.

[0016] Figure 4 This is a schematic diagram of a partially cutaway three-dimensional structure of the first type of the present invention.

[0017] Figure 5 This is a schematic diagram of a second partially cutaway three-dimensional structure of the present invention.

[0018] Figure 6 It is a schematic diagram of the three-dimensional structure of the connecting rod, pressure plate and rotating frame of the utility model.

[0019] Markings in the accompanying drawings: 1: base frame, 2: mounting frame, 3: cylinder, 4: magnet, 41: rotating shaft, 5: filter, 9: spray frame, 10: guide rail, 11: electric slider, 12: connecting rod, 121: limit plate, 13: pressure plate, 131: motor, 132: transmission assembly, 14: rotating frame, 15: sliding block, 16: return spring, 17: contact shaft, 18: bump. DETAILED DESCRIPTION

[0020] The present invention will be further described below in conjunction with specific embodiments. The illustrative embodiments and descriptions of the present invention are used to explain the present invention, but are not intended to limit the present invention.

[0021] Example 1: A percolation device for manufacturing biopharmaceuticals, such as Figures 1-6 As shown, it includes a base frame 1, a mounting frame 2 is fixedly connected to the upper portion of the base frame 1, a cylinder 3 is fixedly connected to the mounting frame 2, the mounting frame 2 is used to mount the cylinder 3, the bottom of the cylinder 3 is fixedly connected to two magnets 4, the two magnets 4 are symmetrically arranged, the base frame 1 is rotatably connected to a rotating shaft 41, the upper end of the rotating shaft 41 is located in the cylinder 3, the rotating shaft 41 is slidably connected to a filter 5, the filter 5 is used to separate the raw material and the extractant, the top of the filter 5 contacts the bottom of the cylinder 3, and the filter 5 is made of iron. The magnet 4 adsorbs the filter 5, and a spray frame 9 is fixedly connected to the upper portion of the cylinder 3. The base frame 1 is provided with a discharge assembly, which can carry the raw material residue after percolation out of the cylinder 3, making it convenient to discharge the raw material residue after percolation.

[0022] The discharging assembly includes a guide rail 10, the guide rail 10 is fixedly connected to the side wall of the base frame 1, and an electric slider 11 is slidably connected to the guide rail 10. Two connecting rods 12 are fixedly connected to the electric slider 11. The electric slider 11 is used to drive the connecting rod 12 to move up and down. The two connecting rods 12 are symmetrically arranged. Both of the connecting rods 12 pass through the filter 5. Both of the connecting rods 12 are fixedly connected to a limiting plate 121. The tops of the two limiting plates 121 are in contact with the bottom of the filter 5. A pressing plate 13 is fixedly connected between the two connecting rods 12. The pressing plate 13 is used to bring the raw material residue out of the cylinder 3. The pressing plate 13 is sleeved on the rotating shaft 41.

[0023] At the beginning, the staff pours the processed motherwort raw material into the cylinder 3, and the motherwort raw material will fall on the filter 5. Then the staff starts the spray rack 9, and the spray rack 9 will continue to spray the extractant into the cylinder 3. The extractant contacts the motherwort raw material, and the active ingredients in the motherwort raw material will dissolve in the extractant. Under the action of gravity, the extractant will move downward and flow down from the mesh of the filter 5. The staff collects the extractant with the active ingredients extracted under the filter 5. After the percolation is completed, the staff closes the spray rack 9, and the spray rack 9 no longer sprays the extractant into the cylinder 3. Then the staff starts the electric slider 11, and the electric slider 11 will move downward along the guide rail 10. The electric slider 11 moves downward to drive the connecting rod 12 to move downward. The connecting rod 12 moves downward to drive the pressure plate 13 and the limit plate 121 to move downward. The limit plate 121 is out of contact with the filter 5, and the pressure plate 13 moves downward to enter the cylinder 3 and After the filter screen 5 is fully opened, the filter screen 5 is pulled out of the reach of the filter screen 5, and the filter screen 5 is pushed downwards, and the filter screen 5 is disengaged from the magnet 4. The magnet 4 no longer attracts the filter screen 5, and the filter screen 5 falls downwards onto the limiting plate 121 under the action of gravity. The filter screen 5 continues to move downwards and will bring the motherwort raw material residue out of the cylinder 3 for the discharge of the raw material residue. Subsequently, the staff cleans the raw material residue on the filter screen 5 and adjusts the electric slider 11 to move upward and reset. The electric slider 11 moves upward and resets to drive the connecting rod 12 to move upward and reset. The connecting rod 12 moves upward and resets to drive the pressing plate 13 and the limiting plate 121 to move upward and reset. The limiting plate 121 moves upward and resets to drive the filter screen 5 to move upward and reset. The filter screen 5 moves upward and resets to contact the magnet 4, and the magnet 4 re-adsorbs the filter screen 5, making it convenient for the next work.

[0024] Example 2: Based on Example 1, Figures 1-6As shown, it also includes a motor 131, and the upper part of the base frame 1 is provided with the motor 131, and a transmission assembly 132 is connected between the motor 131 and the rotating shaft 41, and the upper end of the rotating shaft 41 is fixedly connected to the rotating frame 14, and the motor 131 drives the rotating shaft 41 to rotate through the transmission assembly 132, thereby driving the rotating frame 14 to rotate, and the rotating frame 14 is provided with a plurality of protrusions, and the plurality of protrusions on the rotating frame 14 are evenly spaced. Four sliding blocks 15 are slidably connected to the cylinder 3, and the four sliding blocks 15 are evenly spaced. Two return springs 16 are provided between each sliding block 15 and the cylinder 3, and the two return springs 16 on the same sliding block 15 are symmetrically arranged, and each sliding block 15 is fixed with a contact shaft 17, and each contact shaft 17 will contact the protrusion on the rotating frame 14, and the protrusion on the rotating frame 14 is used to squeeze the contact shaft 17.

[0025] The transmission assembly 132 includes a driving wheel, a driven wheel and a transmission belt. The driving wheel is fixedly connected to the output shaft of the motor 131, and the driven wheel is fixedly connected to the upper end of the rotating shaft 41. A transmission belt is wound between the driving wheel and the driven wheel.

[0026] It also includes a protrusion 18 . A plurality of the protrusions 18 are fixedly connected to the upper portion of the rotating shaft 41 . The plurality of the protrusions 18 are evenly spaced apart. The protrusions 18 are used to squeeze the motherwort raw material in the cylinder 3 .

[0027] When the spray rack 9 starts to spray, the staff starts the motor 131, and the output shaft of the motor 131 rotates through the transmission assembly 132 to drive the rotating shaft 41 to rotate. The rotating shaft 41 rotates and drives the rotating rack 14 to rotate. When the rotating rack 14 rotates, several protrusions on the rotating rack 14 will contact the contact shaft 17 in turn and squeeze the contact shaft 17 towards the direction close to the rotating shaft 41. The return spring 16 is compressed, and the contact shaft 17 moves in the direction close to the rotating shaft 41, driving the sliding block 15 to move in the direction close to the rotating shaft 41. The sliding block 15 will squeeze the motherwort raw material in the cylinder 3, accelerate the dissolution rate of the effective ingredient, and improve the percolation efficiency. The rotating rack 14 continues to rotate and disengages from the contact shaft 17. The return spring 16 will rebound and drive the sliding block 15 to move in the direction away from the rotating shaft 41 to reset. The sliding block 15 moves in the direction away from the rotating shaft 41 to reset, and the contact shaft 17 moves in the direction away from the rotating shaft 41 to reset. After the percolation is completed, the staff turns off the motor 131, and the rotating shaft 41 no longer drives the rotating rack 14 to rotate.

[0028] The rotation of the rotating shaft 41 drives the protrusion 18 to rotate, and the rotation of the protrusion 18 squeezes the motherwort raw material in the cylinder 3, thereby reducing the percolation time and further improving the percolation efficiency.

[0029] It should be understood that the above description is only for illustrative purposes and is not intended to limit the present invention. Those skilled in the art will understand that variations of the present invention will be within the scope of the claims herein.

Claims

1. A percolation device for biopharmaceutical production, characterized by: The invention comprises a base frame (1), a mounting frame (2) is fixedly connected to the upper part of the base frame (1), a cylinder (3) is fixedly connected to the mounting frame (2), two magnets (4) are fixedly connected to the bottom of the cylinder (3), and the two magnets (4) are symmetrically arranged. A rotating shaft (41) is rotatably connected to the base frame (1), the upper end of the rotating shaft (41) is located in the cylinder (3), a filter screen (5) is slidably connected to the rotating shaft (41), the top of the filter screen (5) contacts the bottom of the cylinder (3), the filter screen (5) is made of iron material, and the magnet (4) adsorbs the filter screen (5). A spray frame (9) is fixedly connected to the upper part of the cylinder (3), and a discharge assembly is provided on the base frame (1). The discharge assembly can bring the raw material residue after percolation out of the cylinder (3), so as to facilitate the discharge of the raw material residue after percolation.

2. The percolation device for biopharmaceutical production according to claim 1, characterized in that: The discharge assembly includes a guide rail (10), the guide rail (10) is fixedly connected to the side wall of the base frame (1), an electric slider (11) is slidably connected to the guide rail (10), two connecting rods (12) are fixedly connected to the electric slider (11), the two connecting rods (12) are symmetrically arranged, both of the two connecting rods (12) pass through the filter (5), both of the connecting rods (12) are fixedly connected to a limiting plate (121), the tops of the two limiting plates (121) are in contact with the bottom of the filter (5), a pressing plate (13) is fixedly connected between the two connecting rods (12), and the pressing plate (13) is sleeved with the rotating shaft (41).

3. The percolation device for biopharmaceutical production according to claim 1, characterized in that: The invention also includes a motor (131), the motor (131) is provided on the upper part of the base frame (1), a transmission assembly (132) is connected between the motor (131) and the rotating shaft (41), the upper end of the rotating shaft (41) is fixedly connected to a rotating frame (14), a plurality of protrusions are provided on the rotating frame (14), and the plurality of protrusions on the rotating frame (14) are evenly spaced. Four sliding blocks (15) are slidably connected to the cylinder (3), and the four sliding blocks (15) are evenly spaced. Two return springs (16) are provided between each sliding block (15) and the cylinder (3), and the two return springs (16) on the same sliding block (15) are symmetrically arranged. A contact shaft (17) is fixedly connected to each sliding block (15), and each contact shaft (17) contacts the protrusion on the rotating frame (14).

4. The percolation device for biopharmaceutical production according to claim 3, characterized in that: The transmission assembly (132) includes a driving wheel, a driven wheel and a transmission belt. The driving wheel is fixedly connected to the output shaft of the motor (131), the driven wheel is fixedly connected to the upper end of the rotating shaft (41), and a transmission belt is wound between the driving wheel and the driven wheel.

5. The percolation device for biopharmaceutical production according to claim 1, characterized in that: It also includes convex blocks (18), and a plurality of the convex blocks (18) are fixedly connected to the upper part of the rotating shaft (41), and the plurality of the convex blocks (18) are evenly spaced.

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